Screening of herbal drugs for their potential pharmacological and therapeutical applications
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Scopus Publications
Scopus Publications
Statistical screening and optimization of the medium components for production of novel flavolipid biosurfactant by Flavobacterium sp. MTCC 2495 Research Journal of Pharmaceutical Biological and Chemical Sciences, 2013
Screening of selected herbal plants for anti acne properties International Journal of Drug Development and Research, 2012
Anti-inflammatory and anti-arthritic potential of aqueous and alcoholic extracts of Euphorbia antiquorum Linn Pharmacologyonline, 2011
Protease from an Actinomycetes species: Production, optimization and characterization Indian Drugs, 2009
Effect of Bauhinia variegata bark extract on blood glucose level in normal and alloxanised Diabetic rats Journal of Natural Remedies, 2009
Antiurolithiatic property of moringa oleifera root bark R.V. Karadi, M.B. Palkar, E.N. Gaviraj, N.B. Gadge, V.S. Mannur, K.R. Alagawadi Pharmaceutical Biology, 2008 In spite of tremendous advances in the field of medicine, there is no truly satisfactory drug for the treatment of renal calculi. In the present study, the efficacy of the root bark of Moringa oleifera Lam. (Moringaceae) as an antiurolithiatic agent was investigated using an experimentally induced urolithiatic rat model. Hyperoxaluria was induced in rats using 0.75% ethylene glycol in water. Aqueous (AqE) (200 mg kg− 1 body weight) and alcoholic extracts (AlcE) (200 mg kg− 1 body weight) of the root bark of M. oleifera were given orally in curative and preventive regimens over a period of 28 days. Both the extracts significantly (P < 0.001) lowered the urinary excretion and kidney retention levels of oxalate, calcium and phosphate. Moreover, elevated serum levels of urea nitrogen, creatinine and uric acid were significantly (P < 0.001) reduced by the extracts. The results were comparable with the standard drug, cystone (750 mg kg− 1 body weight). The reduction of stone forming constituents in urine and their decreased kidney retention reduces the solubility product of crystallizing salts such as calcium oxalate and calcium phosphate, which could contribute to the antiurolithiatic property of root bark of M. oleifera.
Antipyretic and wound healing activities of Moringa oleifera Lam. in rats VI Hukkeri, CV Nagathan, RV Karadi, BS Patil Indian Journal of Pharmaceutical Sciences, 2006 Qualitative chemical tests confirmed the presence of phytosterols, glycosides, tannins, and amino acids in the various leaf extracts of Moringa oleifera Lam., whereas its seed extracts showed the presence of phytosterols, glycosides, phenolic compounds, carbohydrates and amino acids. The ethanolic and ethyl acetate extracts of seeds showed significant antipyretic activity in rats, whereas ethyl acetate extract of dried leaves showed significant wound healing activity (10% extracts in the form of ointment) on excision, incision and dead space (granuloma) wound models in rats.
Wound healing activity of Euphorbia hirta Linn. Indian Drugs, 2006
Antiarthritic activity of extracts of Moringa oleifera Lam. roots Indian Drugs, 2006
Hepatoprotective activity of fruit pulp of Annona reticulata Linn. in carbon tetrachloride induced toxicity Indian Drugs, 2004
Heptoprotective activity of bark of Balanites aegyptiaca Linn Journal of Natural Remedies, 2003
Comparative study of leaves and bark of Ailanthus excelsa Roxb. for hepatoprotective activity Indian Drugs, 2003
Anti-inflammatory activity of leaves of Acacia farnesiana willd Indian Drugs, 2002
Wound healing property of Eucalyptus globulus L. leaf extract' Indian Drugs, 2002
