Quality of Life and Predictive Factors among Patients with an Abdominal Stoma: A Cross-Sectional Study in a Teaching Tertiary Hospital Patimah Abdul Wahab, Nurhazelin Mohamed, Norsuzana Ismail, Siti Zuhaidah Shahadan, Intan Idiana Hassan, Haryanto Haryanto Malaysian Journal of Medical Sciences, 2026 Background: An abdominal stoma is instrumental in preserving life; however, its impact on a patient’s quality of life (QoL) is multifaceted and influenced by a complex interplay of various factors, including sociodemographic and clinical factors. This study aimed to assess patients’ QoL and examine its relationship with these factors.Methods: A cross-sectional telephone survey was conducted among patients with abdominal stoma at a teaching tertiary hospital from December 2020 to February 2021. Participants were identified from the medical records of postoperative patients with a stoma and underwent eligibility assessment via medical record reviews. Data on sociodemographic characteristics and clinical conditions were obtained from medical records. A telephone survey employing the City of Hope-Quality of Life-Ostomy Questionnaire (CoH-QoL-OQ) facilitated QoL data collection. Predictor factors of QoL were examined using multiple linear regression.Results: The mean QoL score was 6.86 (standard deviation [SD] = 0.84), indicating a moderate to high QoL. Physical well-being was the most affected (6.29; SD = 0.76), and spiritual well-being was the least affected (8.07; SD = 1.17). Employment status (b = –0.94 [95% CI: –1.67, –0.22]; P = 0.014) and colorectal cancer (CRC) (b = 0.92 [95% CI: 0.13, 1.71]; P = 0.025] were significant predictors of QoL (R² = 0.389).Conclusion: The study found that patients with stomas generally experience a moderate QoL, with poorer QoL associated with unemployment and non-CRC diagnoses. These findings provide valuable insight into the need to strengthen patient-centred care to ensure appropriate and equitable supportive interventions for all patients.
Protective Effects of Curculigo latifolia Root Extract on Testicular Function in Mice Exposed to 7,12-Dimethylbenz(A)Anthracene Haryanto Haryanto, Luthfia Hastiani Muharram, Agus Sutandi, Cusiyani Aprillia, Saepul Muhyi Amirullah, Faisal Anggi Pradita Biosaintifika, 2026 The testis, a vital reproductive organ in males, is highly susceptible to damage from chemotherapy. The root of Curculigo latifolia contains secondary metabolites that have potential as anticancer agents and protective agents for reproductive health. This study aims to evaluate the protective potential of crude extract from C. latifolia in suppressing testicular carcinogenesis induced by DMBA in vivo. This study employed a completely randomized design with five treatment groups, including negative and positive controls, as well as three treatment groups receiving doses of C. latifolia root extract at 300, 600, and 900 mg/Kg body weight. Testicular carcinogenesis was induced by oral administration of DMBA at a dose of 20 mg/Kg body weight twice a week for six weeks. The data of sperm quality, including motility, viability, sperm concentration, and testicular microanatomical structures, analysed by ANOVA one-way test, revealed significant effects from oral administration of C. latifolia root extract (p < 0.05). Overall, C. latifolia root extract improves sperm quality and protects the testicular microanatomical structure against DMBA exposure. Novelty in this study explores the local herbal agent potential (C. latifolia root extract), decreasing reproductive damage and alopecia from DMBA carcinogenic effects. Thus, these findings directly contribute to reaching Sustainable Development Goal 3 (SDG3) by ensuring healthy lives and promoting well-being in all aspects for all ages.
Translation and Validation of the Indonesian Version of the Diabetic Foot Ulcer Scale–Short Form (DFS-SF): A Psychometric Evaluation Haryanto, Patimah Abdul Wahab, Mei Fong Ong, Lilis Lestari, Lidia Hastuti, Kharisma Pratama Malaysian Journal of Nursing, 2026 Background: Diabetic Foot Ulcer (DFU) is a common chronic complication of diabetes that significantly impairs patients’ quality of life. However, a culturally adapted and validated Indonesian DFU specific quality of life instrument to support comprehensive nursing assessment is not yet available. Objective: This study aimed to adapt the DFS-SF (Diabetic Foot Ulcer Scale) into Indonesian using a standardized translation process and to evaluate its psychometric properties, specifically validity and reliability. Methods: This study used a cross-sectional quantitative design and recruited 118 patients from three urban wound care clinics. The original DFS-SF underwent forward-backward translation and cultural adaptation. Internal consistency and construct validity were examined using PLS-SEM (Partial Least Squares Structural Equation Modeling) analysis. Results: The Indonesian DFS-SF demonstrated robust psychometric properties, including high reliability and validity across all domains. Strong internal consistency was observed across all domains, with both Cronbach’s alpha and composite reliability > 0.80. The construct demonstrated adequate convergent validity, evidenced by Average Variance Extracted (AVE) values of 0.60 or higher, and by employing the Fornell-Larcker criterion, discriminant validity was verified. Outer loadings for most indicators were above 0.70, with particularly high loadings for Leisure (≥0.95) and daily activity (≥0.91) domains, indicating robust construct measurement. Conclusion: The Indonesian version demonstrated validity and reliability for assessing quality of life in patients with DFU. To enhance generalizability, future studies should include more diverse populations. This research suggests that the Indonesian version of the DFS-SF can be effectively applied in clinical settings to assess the quality of life among patients with diabetic foot ulcers.
Optimal Wound pH and Related Factors in the Healing Process of Diabetes-Related Foot Ulcer: A Prospective Observational Study Sukarni Sukarni, Suriadi Jais, Haryanto Haryanto, Muhammad Aminuddin, Kanae Mukai, Mayumi Okuwa, Makoto Oe Health Science Reports, 2026 Background and Aims Delayed healing in diabetes‐related foot ulcer (DFU) remains a clinical challenge, and regulating wound pH may offer a promising solution due to its significant role in healing. This study aimed to investigate the relationship between wound pH and healing, and identify factors influencing wound pH at each healing phase. Methods This prospective observational study included 187 people with diabetes‐related ulcer for up to 8 weeks or until healed. Wound pH was measured at the wound bed, wound edge, and peri‐wound. Healing status and phase transition from inflammation to proliferation were assessed using DMIST. Receiver operating characteristic and multivariate regression were used to determine optimal pH cut‐off and influencing factors. Results Healing within 3 days was significantly associated with wound bed pH < 6.7 and wound edge pH < 6.8, while wound edge pH > 7.7 indicated transition to the proliferative phase. In the inflammatory phase, higher wound edge pH was associated with inflammation, absence of systemic infection, and necrotic tissue color. In the proliferative phase, lower pH was associated with higher albumin, absence of maceration, use of hydrofiber dressing at both the wound bed and edge, no stingless bee honey on the wound bed, and use of dialkyl carbamoyl chloride and calcium alginate on the wound edge. Conclusions This study provides novel evidence on specific wound pH thresholds associated with healing outcomes and phase transition in DFU highlighting the importance of controlling pH‐related factors to prevent delayed healing and promote healing.
Relationship between microbiota and healing status in diabetes-related foot ulcers treated with Trigona honey Sukarni Sukarni, Mao Kunimitsu, Kazuhiro Ogai, Delima Fajar Liana, Mahyarudin Mahyarudin, Muhammad Aminuddin, Kanae Mukai, Haryanto Haryanto, Suriadi Jais, Makoto Oe Journal of Tissue Viability, 2026 AIMS: Diabetes-related foot ulcers (DFUs) are a major complication of diabetes, and treatment with honey, which has antimicrobial properties, has been utilized in patients. However, the effects have been shown to vary, with the causes of these differences remaining unclear. Recently, microbiota has been reported to be associated with wound healing. Therefore, we hypothesized that differences in microbiota might explain the variations observed in response to honey. The present study aimed to investigate the relationship between the microbiota and the healing status in DFUs treated with Trigona honey. METHODS: A cohort study involving 12 DFUs categorized into healing and deteriorating groups was conducted. Wound and peri-wound microbiota observed at baseline and at 1 week later (after starting honey application) were investigated and then compared in the healing status. RESULTS: Enterococcus was higher in the deteriorating group at baseline in the wound (p = 0.02), while Corynebacterium was higher in the healing group at 1 week later in the peri-wound skin (p = 0.02). Changes in the relative abundance of Prevotella and Brevundimonas in the peri-wound skin significantly differed based on the healing status. CONCLUSION: The findings suggest that the honey's effects might differ based on the composition of the wound microbiota, and they highlight the bacterial interactions with the changes in the wound and peri-wound skin environment induced by the honey. These results also imply that honey therapy on its own may not be enough for treating DFUs. This study is limited by the small sample size and short follow-up period; further research will need to explore combined treatment strategies and long-term microbiota dynamics to improve DFU management.
A Randomized Clinical Trial Study on the Prevention Strategy and Early Detection of Ulcer Recurrence in Patients with Type 2 Diabetes Mellitus Using the Risk of Recurrence Ulcer Tool Haryanto Haryanto, Yunita Sari, Elveria Panjaitan, Juminar Juminar, David Armstrong International Journal of Lower Extremity Wounds, 2025 This study aimed to evaluate the effectiveness of prevention strategies and detect the risk level of recurrence. A randomized controlled trial (RCT) was conducted. Sixty participants were split into two groups: an intervention group consisting of 30 individuals and a control group also with 30 participants. For the intervention group, education and guidance on foot examination, foot care, dietary habits, exercise, and stress management were provided for 1 to 1.5 h each month. However, the control group only received standard care and education through a pamphlet at baseline. The both groups, the baseline risk level of ulcer recurrence score was assessed using INDIFURUTO (Indonesian Diabetic Foot Ulcer Recurrence Assessment Tool). The follow-up period was three months. A General Linear Model (GLM) repeated measures (ANCOVA) analysis was employed to compare the quality of life and risk level between the two groups at baseline and third follow-up. Risk factors for recurrence score in the intervention group significantly decreased after 3 months. These included improvements in mobility ( P = .04), anxiety/depression ( P < .001), EuroQol Visual Analogue Scale score ( P = .004), and INDIFURUTO score ( P = .004). The combination of preventive strategies could reduce the risk of recurrence ulcer and improve the quality of life. Trial registration number ClinicalTrials.gov Identifies: NCT06434922.
Correlation Between Bacteria Count Using a Rapid Bacterium Counting System and Changes in Wound Area on Diabetic Foot Ulcers in Indonesia: A Prospective Study Haryanto Haryanto, Suriadi Jais, Supriadi Supriadi, Imran Imran, Kazuhiro Ogai, Makoto Oe, Mayumi Okuwa, Junko Sugama International Journal of Lower Extremity Wounds, 2025 This study aimed to clarify the correlation between changes in bacterial number and wound area in diabetic foot ulcers (DFUs). This study used a prospective longitudinal cohort design. A total of 30 participants met the inclusion criteria. Changes in bacterial number and wound area were evaluated weekly until week 4. The chi-square test indicated no significant correlation between biofilm formation and wound area (p = 0.32) but a significant correlation between bacterial count and wound area (p = 0.05). Logistic regression analysis showed a significant correlation between bacterial count and changes in wound area (odds ratio, 0.60; 95% confidence interval [CI], 0.372-0.997; p = 0.04). The receiver operating characteristic analysis showed an area under the curve of 0.660 (95% CI, 0.52-0.79; p = 0.03) with a sensitivity of 97% and specificity of 88%. The present prospective longitudinal cohort study demonstrated the correlation between bacterial count changes and wound area in DFUs. Our results suggest that changes in bacterial count could help wound healing evaluations.
Pilot Implementation of a Thermography-Driven Preventive Foot Care Protocol for Diabetes-Related Foot Ulcers in Community Health Centers: Non-Randomized Controlled Trial Makoto Oe, Haryanto Haryanto, Kanae Mukai, Mao Kunimitsu, Suriadi Jais International Journal of Lower Extremity Wounds, 2025 Aim The purpose of this study was to clarify the effectiveness and implementation issues of a thermography-driven preventive foot care protocol for diabetes-related foot ulcers in Indonesian community health centers. Methods In the two trial centers examined between May 2023 and May 2024, one provided protocol-based care (Intervention group; n = 71), while the other provided standard education (Control group; n = 71). Participants were monitored for ulceration over a 1-year period. Results There was no significant difference in the number of participants with ulceration between the intervention and control group (6 vs 8 cases, p = 0.573). However, there was a shorter time to ulceration (203.8 ± 8.7 vs 350.0 ± 13.9 days, p = 0.048) in the intervention group. Over the 1-year follow-up, protocol compliance was 100% for examinations, but 0% for callus and nail care. Participants without risk factors, such as neuropathy or angiopathy, also developed ulcers. Conclusions Results suggested this protocol was ineffective in the community health center. It will be necessary to clarify the risk factors for foot ulcers in the target population, establish an appropriate protocol, prepare an environment for its implementation, and then conduct a randomized controlled trial in the future.
The relationship between infection severity, wound categorization, and foot care in type 2 diabetes mellitus patients with recurring diabetic foot ulcers Medical Journal of Malaysia, 2024
Quality of life in patients with recurrent diabetic foot ulcers Haryanto Haryanto, Lestari Makmuriana, Hartono Hartono, Desti Dwi Arini, Sri Ariyanti, Yunita Sari, Mahin Ridlo Ronas, Junaidi Junaidi, Ledy Ervita Central European Journal of Nursing and Midwifery, 2023
Effectiveness of indonesian honey on the acceleration of cutaneous wound healing: An experimental study in Mice Wounds, 2012
RECENT SCHOLAR PUBLICATIONS
Faktor-Faktor Yang Mempengaruhi Underreporting Dan Blaming Culture Pada Insiden Keselamatan Pasien: Scoping Review R Raudha, WK Bhakti, H Haryanto Borneo Nursing Journal (BNJ) 8 (2), 1489-1494 , 2026 2026
Implementasi Komunikasi Terapeutik Perawat Dalam Peningkatan Mutu Pelayanan Kesehatan: Scoping Review YRA Wijoyo, WK Bhakti, H Haryanto Borneo Nursing Journal (BNJ) 8 (2), 1477-1488 , 2026 2026
Quality of Life and Predictive Factors among Patients with an Abdominal Stoma: A Cross-Sectional Study in a Teaching Tertiary Hospital PA Wahab, N Mohamed, N Ismail, SZ Shahadan, II Hassan, H Haryanto Malaysian Journal Medical Science, 135–145 , 2026 2026
The Effects of Moderate and Low-Intensity Resistance Exercise on HbA1c Reduction in Patients with Type 2 Diabetes Mellitus DR Larasati, Haryanto, L Hastuti, S Jais, I Imran Jurnal Kesehatan Manarang 12 (1), 77-84 , 2026 2026
Work environment and nurses' perspectives on missed nursing care: A scoping review SS Nurhidayati Nurhidayati, Haryanto Haryanto Journal of Mental Health Concerns 5 (1) , 2026 2026
RISK FACTORS FOR DIABETES MELLITUS AND THEIR ASSOCIATION WITH BLOOD GLUCOSE LEVELS IN ADOLESCENTS FM Sister, R Mardiyani, W Wuriani, H Haryanto, L Hastuti, K Pratama, ... Jurnal Persatuan Perawat Nasional Indonesia (JPPNI) 10 (3), 325-332 , 2026 2026
Analysis of Risk Factors For Adolescent Pregnancy And Innovations In Community-Based Prevention Interventions In Rural Areas BM Iswari, L Hastuti, L Lestari, S Jais, Haryanto International Journal of Humanities Education and Social Sciences 5 (5) , 2026 2026
Work environment and nurses' perspectives on missed nursing care: A scoping review Nurhidayati, Haryanto, Suriadi Journal of Mental Health Concerns 5 (1) , 2026 2026
Model Komunikasi Efektif Tenaga Kesehatan Keluarga Pasien di ICU: Scoping Review DK Welly, H Haryanto, S Suriadi, I Imran JUKEJ: Jurnal Kesehatan Jompa 5 (1), 455-467 , 2026 2026
EDUCATION INTERVENTIONS FOR REDUCING INTERDIALYTIC WEIGHT GAIN IN HEMODIALYSIS PATIENTS: A SCOPING REVIEW MM Ratri, Suriadi, Supriadi, Haryanto Jurnal Kesehatan Tambusai 7 (1) , 2026 2026
Organizational, individual, and psychosocial determinants of burnout syndrome among hospital nurses: A scoping review SS Rahayu Rahayu, Haryanto Haryanto Journal of Mental Health Concerns 4 (7) , 2026 2026
Translation and Validation of the Indonesian Version of the Diabetic Foot Ulcer Scale–Short Form (DFS-SF): A Psychometric Evaluation Haryanto, PA Wahab, MF Ong, L Lestari, L Hastuti, K Pratama The Malaysian Journal of Nursing (MJN) 17 (4), 1-10 , 2026 2026
Peningkatan Kompetensi Perawat melalui Program Pelatihan Perawatan Luka: Kolaboratif Internasional Haryanto, K Pratama, PBA Wahab, AB Yusoff, Dahlia DedikasiMU: Journal of Community Service, 172-178 , 2026 2026
Faktor-Faktor Yang Memengaruhi Tugas Kader Posyandu Dalam Mendukung Integrasi Pelayanan Keehatan Primer di Puskesmas: Scoping Review I Zamzami, CK Jiu, L Hastuti, Haryanto Jurnal Ners 10 (2) , 2026 2026
Audio-visual learning for the prevention of bloodstream infections in hemodialysis patients with double-lumen catheters: A literature review F Widyanti, Haryanto, Suriadi Journal of Mental Health Concerns 4 (6) , 2026 2026
Psychological and behavioural determinants in type 2 diabetes self-management: A scoping review SS Nurul Ratna Sari, Haryanto Haryanto Journal of Mental Health Concerns 4 (6) , 2026 2026
Forensic nurses’ mental well-being in handling cases insights from jean watson’s caring theory: A scoping review SS Sudarwati Sudarwati, Haryanto Haryanto Journal of Mental Health Concerns 4 (6) , 2026 2026
Pengaruh Terapi Murotal Al-Qur’an Irama Nahawand Terhadap Penurunan Skor Kecemasan Pasien Dispepsia: Scooping Review D Radhamudi, Suriadi, Haryanto, J Pradika Jurnal Ners 10 (2) , 2026 2026
Comparison of shid and wagner wound classifications for assessing quality of life in patients with diabetic foot ulcers Suriadi, HPDA Anggreni Journal of Mental Health Concerns 4 (6) , 2026 2026
Implementation of patient-centered care in transforming mental health services: A scoping review P Ariyani, CK Jiu, L Lestari, S Jais, H Haryanto Journal of Mental Health Concerns 4 (6), 436-443 , 2026 2026
MOST CITED SCHOLAR PUBLICATIONS
Relationship between maceration and wound healing on diabetic foot ulcers in Indonesia: a prospective study H Haryanto, D Arisandi, S Suriadi, I Imran, K Ogai, H Sanada, M Okuwa, ... International wound journal 14 (3), 516-522 , 2017 2017 Citations: 64
Effectiveness of Indonesian honey on the acceleration of cutaneous wound healing: an experimental study in mice Haryanto, T Urai, K Mukai, S Jais, J Sugama, T Nakatani Wounds: a compendium of clinical research and practice , 2012 2012 Citations: 64
The differences in health-related quality of life between younger and older adults and its associated factors in patients with type 2 diabetes mellitus in Indonesia S Yunita, I Atyanti, U Arif, Setyo, T Agis, S Rahmi, S Keksi, Girindra, ... Health and Quality of Life Outcome, 1-10 , 2021 2021 Citations: 48
The barriers and facilitators of foot care practices in diabetic patients in Indonesia: A qualitative study Y Sari, S Yusuf, H Haryanto, A Sumeru, S Saryono Nursing Open 9 (6), 2867-2877 , 2022 2022 Citations: 43
The cultural beliefs and practices of diabetes self-management in Javanese diabetic patients: An ethnographic study Y Sari, S Yusuf, Haryanto, LH Kusumawardani, A Sumeru, E Sutrisna, ... Heliyon, 1-9 , 2022 2022 Citations: 43
Nursing student's knowledge and attitude toward diabetic ulcer care and their contributing factors in Indonesia Y Sari, AS Upoyo, A Sumeru, S Yusuf, Haryanto, Nuriya, A Taufik International Journal of Nursing Sciences , 2022 2022 Citations: 26
Herbal bioactives for wound healing application IS Bakshi, H Chopra, M Sharma, D Kaushik, R Pahwa, Haryanto Herbal Bioactive Based Drug Delivery System Challenges and Opportinities … , 2022 2022 Citations: 18
A prospective observational study using sea cucumber and honey as topical therapy for diabetic foot ulcers in Indonesia Haryanto, K Ogai, Suriadi, G Nakagami, M Oe, T Nakatani, M Okuwa, ... Journal of Wellness and Health Care 41 (2), 41-56 , 2017 2017 Citations: 18
Students with Intellectual Disability in Special Needs School: A Qualitative Study CK Jiu, N Zulfia, ID Rahayu, GJ Putra, Wuriani, Haryanto nternational Journal of Multidisciplinary Research and Publications (IJMRAP … , 2020 2020 Citations: 16
Pressure ulcers related to medical device in intensive care in Indonesia: A prospective study K Masyitha, Haryanto, D Puspita Enfermeria clinica 30, 87-91 , 2020 2020 Citations: 16
The Relationship between Cutaneous Wounds Made on Obese Mice or Those with Decreased Body Weight and Serum Leptin Level T Urai, Haryanto, K Mukai, T Matsushita, K Asano, Y Nakajima, M Okuwa, ... Health 8 (11), 1015 , 2016 2016 Citations: 12
Evaluating the cost‐effectiveness of diabetic foot ulcer management by wound care specialists in Indonesia S Jais, M Oe, H Sanada, A Sasongko, H Haryanto Wound Repair and Regeneration 32 (1), 80-89 , 2024 2024 Citations: 11
Quality of life in patients with recurrent diabetic foot ulcers Haryanto, L Makmuriana, Hartono, DD Arini, S Ariyanti, Y Sari, MR Ronas, ... Central European Journal of Nursing and Midwifery , 2023 2023 Citations: 10
Berpikir Kritis dalam Proses Keperawatan : Scoping Review E Nilaprapti, H Haryanto, WK Bhakti Jurnal Keperawatan dan Kesehatan 15 (1), 20-26 , 2024 2024 Citations: 8
Effects of understanding wellbeing on psychological aspects and wound healing in patients with diabetic foot ulcer recurrence: a pilot randomised controlled trial Imran, Defa Arisandi,Haryanto, Suriadi Jais, Makoto Oe, Okuwa Mayumi ... The diabetic foot journal, 119-126 , 2018 2018 Citations: 8
Effectiveness of online education on thermography-based diabetic foot ulcer prevention for wound care specialists: a single-group quasi-experimental study M Aminuddin, Sukarni, Haryanto, S Jais, A Yamada, K Mukai, M Oe Diabetology international 16 (2), 356-364 , 2025 2025 Citations: 7
Prevention Strategy for Ulcer Recurrence in Patients with Type II Diabetes Mellitus: A Quasi-Experimental Study J Suriadi, K Pratama, J Fahrain, J Pradika, T Kardiatun, WK Bhakti, ... Iranian Journal of Nursing and Midwifery Research 28 (2), 139-143 , 2023 2023 Citations: 7
A descriptive analysis of patients with stoma attending a tertiary hospital on the East Coast of peninsular Malaysia PA Wahab, N Mohamed, N Ismail, II Hassan, H Haryanto INTERNATIONAL JOURNAL OF CARE SCHOLARS 7 (3), 4-10 , 2024 2024 Citations: 6
Efektivitas Madu dalam Perawatan Luka pada Pasien Diabetes Mellitus : A Literature Review EA Kaeng, H Haryanto Jurnal Keperawatan dan Kesehatan 13 (2), 97-103 , 2022 2022 Citations: 6
Pengaruh Pendidikan Kesehatan Terhadap Tingkat Pengetahuan siswa Kelas 5 (Lima) SD Negeri 21 Sungai Raya tentang Jajanan Sehat Hadian Pat Usmayanti, Haryanto, Kharisma Pratama Jurnal Keperawatan dan Kesehatan , 2020 2020 Citations: 6