SANAMBATLA VANITHA

@sietk.org

ASSOCIATE PROFESSOR
SIDDARTH INSTITUTE OF ENGINEERING AND TECHNOLOGY (AUTONOMOUS), PUTTUR

SANAMBATLA VANITHA


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https://researchid.co/vanithasanambatla

RESEARCH, TEACHING, or OTHER INTERESTS

Analytical Chemistry, Spectroscopy
5

Scopus Publications

47

Scholar Citations

3

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • Synthesis, spectral characterization, and biological studies of Schiff bases and their mixed ligand Zn(II) complexes with heterocyclic bases
    S. Vanitha, N. Sathish Kumar, K. Reddi Mohan Naidu, M. Balaji, A. Varada Reddy, N. Saritha
    Inorganic and Nano Metal Chemistry, 2023
    In the present study, six mononuclear Zinc(II) complexes, [Zn(L1)(6-Methyl-2,2′-bpy)] (1), [Zn(L1)(1,10-Phen)] (2), [Zn(L1)(5-Amino-1,10-Phen)] (3), [Zn(L2)(6-Methyl-2,2′-bpy)] (4), [Zn(L2)(4,4′-Di-tert-butyl-2,2′-bpy)] (5), and [Zn(L2)(1,10-Phen)] (6) formed from Schiff bases, 2-methyl-1-phenyl-1-(pyridin-2-ylmethylimino)propan-2-ol (L1) and 4-chloro-5-methyl-2-(1-(pyridin-2-ylmethylimino)ethyl)phenol (L2) were synthesized. The synthesized Schiff base ligands and metal complexes were characterized by different spectroscopic techniques such as FTIR, UV–Visible, 1H & 13C NMR spectroscopy, in addition to Powder X-ray diffraction and cyclic voltammetry. Further, the synthesized metal complexes (1–6) and their parental Schiff bases (L1, L2) were evaluated for antibacterial, antifungal, and antioxidant activities. Of those, Complex 1 was shown to have significant antibacterial activity against all of the evaluated microorganisms. Schiff base ligands, L1 and L2, complexes 1, 4, and 5 were shown to have superior antifungal activity against Aspergillus niger than the standard drug, fluconazole. In addition, the synthesized compounds achieved good antioxidant activities when compared to the standard Ascorbic acid.
  • Biological studies of Schiff base, 2-(1-hydroxycyclohexyl) phenyl methylene hydrazine carbothioamide and its Cu(II) and Zn(II) metal complexes
    Prasuna M Kamatam, Vanitha Sanambatla, Seshaiah Kalluru
    Journal of Medical Pharmaceutical and Allied Sciences, 2022
    Condensation of 1-hydroxycyclohexyl phenyl ketone with hydrazine carbothioamide produced a new Schiff base, 2-(1-hydroxycyclohexyl) phenyl methylene hydrazine carbothioamide. The Cu(II) and Zn(II) metal complexes of the Schiff base were prepared. The different spectroscopic methods such as FT-IR, UV-Visible, 1H NMR, and 13C NMR spectroscopy were used to elucidate the structural characteristics of the synthesized compounds. Further, the biological applications of the prepared Schiff bases and its metal complexes were studied for the antibacterial activity. The antimicrobial investigation was carried out against different Gram positive and Gram negative bacteria like Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa. According to the findings, the prepared Cu(II) and Zn(II) metal complexes are more biologically active than Schiff base ligand, and among all tested bacterial species, Staphylococcus aureus growth was most inhibited by prepared compounds. Keywords: 1-hydroxycyclohexyl phenyl ketone, Hydrazine carbothioamide, Schiff base, Cu (II), Zn (II)
  • Antimicrobial and antioxidant studies of Schiff base, 2-(2-hydroxy-2-methyl-1-phenylpropylidene) hydrazine carbothioamide and its mixed ligand cd (II) complexes
    Journal of Medical Pharmaceutical and Allied Sciences, 2022
  • Synthesis, spectral characterization, molecular docking studies, biological activity of (E)-2-((E)-3-(3,4,5-trimethoxyphenyl)allylidene) and (E)-N-phenyl 2-((E)-3-(3,4,5-trimethoxyphenyl)allylidene)hydrazinecarbothioamides and their Cu(II) complexes
    A. Sreenath Reddy, Jincheng Mao, S. Vanitha, Vishnu Nayak Badavath, L. Sivarama Krishna, M. Lavanya, M.V. Jyothi kumar
    Journal of Saudi Chemical Society, 2019
    Two slightly distorted octahedral complexes of copper(II) with (E)-2-((E)-3-(3,4,5-trimethoxyphenyl)allylidene)hydrazinecarbothioamide (L1) common name 3,4,5-trimethoxy-cinnamaldehydethiosemicarbazone and (E)-N-phenyl-2-((E)-3-(3,4,5-trimethoxyphenyl)-allylidene)hydrazinecarbothioamide (L2) common name 3,4,5-trimethoxycinnamaldehyde-4-phenylthiosemicarbazone have been synthesized. The two free ligands and their copper(II) complexes were characterized by spectroscopic techniques like FT-IR, FT-Raman, UV, EPR, Powder X-ray diffraction and cyclic voltammetry. The EPR spectra evidenced a rhombically distorted octahedron geometry for both the copper(II) complexes. The band gap calculations for the ligands L1, L2 and their complexes Cu(L1)2Cl2 and Cu(L2)2Cl2 were found to be 2.98, 2.61, 2.66 and 2.50 eV respectively. Cu(L1)2Cl2 and Cu(L2)2Cl2 have shown 50% of viability at 80 μg/ml and 60 μg/ml. The anti-oxidant activity study revealed that the compounds are good reductants of DPPH radical. Moderate to good anti-bacterial activity is shown by the compounds against the Gram-positive and Gram-negative bacteria. Molecular docking studies have been carried out to predict the orientation and binding mode of analysis in the active site. The synthesized ligand and complex well occupy (catalytic triad and adenine-binding site) in the active site of β-ketoacyl-acyl carrier protein synthase III enzyme, and also well occupy in helix 11 (in the DCS complex) of human estrogen receptor. Moreover they form water mediated hydrogen bond and hydrogen bond with Cys530 residue.
  • Synthesis, characterization antimicrobial and antioxidant activities of 2,4-dihydroxybenzaldehyde-4-phenyl-3-thiosemicarbazone (DHBPTSC) and its Pd(II), Ni(II)dppm mixed ligand and cu(II) complex having heterocyclic bases
    V. Kumar, Y. Sarala, Asha Siddikha, S. Vanitha, S. Babu, A. V. Reddy
    Journal of Applied Pharmaceutical Science, 2018
    © 2018 V. Asha Kumar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License -NonCommercialShareAlikeUnported License (http://creativecommons.org/licenses/by-nc-sa/3.0/). *Corresponding Author A. Varada Reddy, Analytical Division, Department of Chemistry, Sri Venkateswara University, Tirupati 517502, India. E-mail: ammireddyv @ yahoo.co.in Synthesis, Characterization Antimicrobial and Antioxidant Activities of 2,4-dihydroxybenzaldehyde-4-phenyl-3-thiosemicarbazone (DHBPTSC) and its Pd(II), Ni(II)dppm Mixed Ligand and Cu(II) Complex having Heterocyclic Bases

RECENT SCHOLAR PUBLICATIONS

  • Immediate Effect of Cold Water Enema On Fever Among Adults: A Single Arm Study
    MK Shradha, DR Lakshmeesha, SS Vanitha, NK Saritha
    AIJFR-Advanced International Journal for Research 7 (1) , 2026
    2026.0
  • Synthesis, spectral characterization, and biological studies of Schiff bases and their mixed ligand Zn (II) complexes with heterocyclic bases
    S Vanitha, N Sathish Kumar, K Reddi Mohan Naidu, M Balaji, ...
    Inorganic and Nano-Metal Chemistry 53 (8), 803-814 , 2023
    2023.0
    Citations: 2
  • Antimicrobial and antioxidant studies of Schiff base, 2-(2-hydroxy-2-methyl-1-phenylpropylidene) hydrazine carbothioamide and its mixed ligand cd (II) complexes
    V Sanambatla, SK Nara, B Hari, VR Ammireddy, S Nimmakayala
    Journal of medical pharmaceutical and allied sciences, 4470-4476 , 2022
    2022.0
    Citations: 3
  • Synthesis, spectral characterization, molecular docking studies, biological activity of (E)-2-((E)-3-(3, 4, 5-trimethoxyphenyl) allylidene) and (E)-N-phenyl 2-((E)-3-(3, 4, 5 …
    AS Reddy, J Mao, S Vanitha, VN Badavath, LS Krishna, M Lavanya
    Journal of Saudi Chemical Society 23 (7), 947-957 , 2019
    2019.0
    Citations: 10
  • Synthesis and Spectral Characterization of Cu (II) Complexes with 2-Hydroxy-2-Methyl Propiophenone Picolylamine and Diimine Co-Ligands
    S Vanitha, KM Prasuna, N Saritha, A Varada Reddy
    Int J Research and Analytical Reviews 6 (2), 7-14 , 2019
    2019.0
    Citations: 2
  • Synthesis, characterization antimicrobial and antioxidant activities of 2, 4-dihydroxybenzaldehyde-4-phenyl-3-thiosemicarbazone (DHBPTSC) and its Pd (II), Ni (II) dppm mixed …
    VA Kumar, Y Sarala, A Siddikha, S Vanitha, S Babu, AV Reddy
    Journal of Applied Pharmaceutical Science 8 (4), 071-078 , 2018
    2018.0
    Citations: 30
  • Biological studies of Schiff base, 2-(1-hydroxycyclohexyl) phenyl methylene hydrazine carbothioamide and its Cu (II) and Zn (II) metal complexes
    PM Kamatam, V Sanambatla, S Kalluru

MOST CITED SCHOLAR PUBLICATIONS

  • Synthesis, characterization antimicrobial and antioxidant activities of 2, 4-dihydroxybenzaldehyde-4-phenyl-3-thiosemicarbazone (DHBPTSC) and its Pd (II), Ni (II) dppm mixed …
    VA Kumar, Y Sarala, A Siddikha, S Vanitha, S Babu, AV Reddy
    Journal of Applied Pharmaceutical Science 8 (4), 071-078 , 2018
    2018.0
    Citations: 30
  • Synthesis, spectral characterization, molecular docking studies, biological activity of (E)-2-((E)-3-(3, 4, 5-trimethoxyphenyl) allylidene) and (E)-N-phenyl 2-((E)-3-(3, 4, 5 …
    AS Reddy, J Mao, S Vanitha, VN Badavath, LS Krishna, M Lavanya
    Journal of Saudi Chemical Society 23 (7), 947-957 , 2019
    2019.0
    Citations: 10
  • Antimicrobial and antioxidant studies of Schiff base, 2-(2-hydroxy-2-methyl-1-phenylpropylidene) hydrazine carbothioamide and its mixed ligand cd (II) complexes
    V Sanambatla, SK Nara, B Hari, VR Ammireddy, S Nimmakayala
    Journal of medical pharmaceutical and allied sciences, 4470-4476 , 2022
    2022.0
    Citations: 3
  • Synthesis, spectral characterization, and biological studies of Schiff bases and their mixed ligand Zn (II) complexes with heterocyclic bases
    S Vanitha, N Sathish Kumar, K Reddi Mohan Naidu, M Balaji, ...
    Inorganic and Nano-Metal Chemistry 53 (8), 803-814 , 2023
    2023.0
    Citations: 2
  • Synthesis and Spectral Characterization of Cu (II) Complexes with 2-Hydroxy-2-Methyl Propiophenone Picolylamine and Diimine Co-Ligands
    S Vanitha, KM Prasuna, N Saritha, A Varada Reddy
    Int J Research and Analytical Reviews 6 (2), 7-14 , 2019
    2019.0
    Citations: 2
  • Immediate Effect of Cold Water Enema On Fever Among Adults: A Single Arm Study
    MK Shradha, DR Lakshmeesha, SS Vanitha, NK Saritha
    AIJFR-Advanced International Journal for Research 7 (1) , 2026
    2026.0
  • Biological studies of Schiff base, 2-(1-hydroxycyclohexyl) phenyl methylene hydrazine carbothioamide and its Cu (II) and Zn (II) metal complexes
    PM Kamatam, V Sanambatla, S Kalluru