Dr Shanmuga Sundar Saravanabhavan

Scopus Publications

Demethoxycurcumin exhibits amoebicidal activity against Acanthamoeba triangularis trophozoites and cysts and inhibits encystation
Rachasak Boonhok, Wilaiwan Senghoi, Aman Tedasen, Suthinee Sangkanu, Chooi Ling Lim, Maria de Lourdes Pereira, Mohammed Rahmatullah, Polrat Wilairatana, Christophe Wiart, Karma G. Dolma, Alok K. Paul, Madhu Gupta, Md Atiar Rahman, Kingkan Bunluepuech, Shanmuga Sundara, Tooba Mahboob, Veeranoot Nissapatorn
Current Research in Parasitology and Vector Borne Diseases, 2026
Acanthamoeba is a ubiquitous free-living protist commonly found in soil and water, with the T4 genotype responsible for most human infections. Treatment remains challenging due to the limited efficacy of current therapeutics and the parasite’s ability to form a highly resistant double-walled cyst. In this study, we investigated the anti- Acanthamoeba potential of demethoxycurcumin, a bioactive curcumin derivative, using A . triangularis , a clinically relevant T4 genotype species. Among the curcumin derivatives tested, demethoxycurcumin exhibited the strongest amoebicidal activity, effectively targeting both trophozoite and cyst forms. Scanning electron microscopy revealed pronounced ultrastructural damage, including loss of acanthopodia, membrane disruption, and pore formation, indicating compromised cellular integrity. Notably, demethoxycurcumin significantly inhibited encystation under starvation conditions, maintaining the parasite in the trophozoite stage. Consistently, transcriptional analysis showed that key autophagy-related genes ( Ac ATG3, Ac ATG8b, Ac ATG12, and Ac ATG16) remained close to basal levels following sublethal treatment, supporting suppression of autophagy-associated encystation. Molecular docking and dynamics simulations showed that demethoxycurcumin binds stably to Vps34 and Cdc2b of Acanthamoeba spp., forming key hydrogen bonds with LYS40, GLU90, LEU92, ALA153, and PHE155, along with π interactions that support enzymatic regulation. Compared to curcumin, demethoxycurcumin formed fewer but significant contacts, maintaining persistent binding and moderate flexibility over 100 ns, highlighting its potential as a selective modulator of autophagy and cell cycle pathways. Complementary network pharmacology analyses identified overlapping targets between demethoxycurcumin and A. triangularis infection-related proteins, highlighting hub genes such as AKT1, TNF, MMP9, CDK1, and PIK3C3, and enriched pathways in autophagy, immune regulation, oxidative stress responses, and kinase-mediated signaling. Collectively, these findings suggest that demethoxycurcumin exerts anti- Acanthamoeba activity through coordinated disruption of autophagy and cell-cycle regulatory networks, leading to arrest and impaired encystation of Acanthamoeba trophozoites. • Demethoxycurcumin exerted potent amoebicidal activity against Acanthamoeba triangularis trophozoites and cysts. • Treatment induced acanthopodia loss, membrane disruption, and pore formation, compromising cellular integrity. • Encystation was inhibited under starvation, maintaining amoebas in the trophozoite stage. • Sublethal exposure suppressed autophagy-related pathways, with ATG gene expression remaining near basal levels. • Acanthamoeba Vps34-mediated autophagy and Cdc2b-dependent cell-cycle regulation were implicated in trophozoite arrest.
A synergistic nanoformulation of propolis and chlorhexidine against Acanthamoeba: encapsulation efficiency, release kinetics, and safety evaluation
Nivetha Marimuthu, Siriphorn Chimplee, Shanmuga Sundar Saravanabhavan, Ryan V. Labana, Victor Varun Raju Sowri, Tajudeen O. Jimoh, Wenn-Chyau Lee, Tadesse Hailu, Guo-Jie Brandon-Mong, Patcharaporn Boonroumkaew, Thiranut Jaroonwitchawan, Watcharapong Mitsuwan, Chooi Ling Lim, Rhun Yian Koh, Samudi Chandramathi, Muhammad Nawaz, Maria de Lourdes Pereira, Christophe Wiart, Sonia M.R. Oliveira, Veeranoot Nissapatorn
Peerj, 2025
Background Acanthamoeba spp. are opportunistic protozoa that produce highly resistant cysts, complicating the treatment of ocular infections. Methods We assessed the anti- Acanthamoeba activity and cytotoxicity of chitosan nanoparticles loaded with propolis extracts from three stingless bee species, individually or combined with chlorhexidine (CHX). Encapsulation efficiency (EE), drug release kinetics, pH sensitivity, and anti- Acanthamoeba activity against trophozoite and cyst stages of four Acanthamoeba strains were evaluated. Additionally, cytotoxicity against Vero cells was examined. Results The formulations demonstrated excellent EE (81–92%), with the combinations of Propolis 2, Propolis 3, and chlorhexidine achieving maximum drug entrapment and sustained release (>80%). It also exhibited the most effective cysticidal activity (minimal inhibitory cystic concentration (MICC) 1.25%) against A. polyphaga and the lowest toxicity (Minimal Cytotoxicity Concentration 2.5%) toward normal mammalian cells. Drug release conformed to non-Fickian (Case II) diffusion behavior and was enhanced in acidic pH conditions, which are relevant to disease. Scanning electron microscopy revealed morphological damage to the cyst walls. Conclusion These results highlight that propolis–CHX-loaded chitosan nanoparticles (CS-NPs) show promise as a targeted, biocompatible therapy against drug-resistant Acanthamoeba cysts.
A Review on Phytochemistry, Ethnopharmacology, and Antiparasitic Potential of Mangifera indica L.
Diana Mendonça, Yen-Zhi Tan, Yi-Xin Lor, Yi-Jing Ng, Abolghasem Siyadatpadah, Chooi-Ling Lim, Roghayeh Norouzi, Roma Pandey, Wenn-Chyau Lee, Ragini Bodade, Guo-Jie Brandon-Mong, Ryan V. Labana, Tajudeen O. Jimoh, Ajoy Kumar Verma, Tadesse Hailu, Shanmuga S. Sundar, Anjum Sherasiya, Sónia M. R. Oliveira, Ana Paula Girol, Veeranoot Nissapatorn, Maria de Lourdes Pereira
Pharmaceuticals, 2025
Parasitic infections remain a major global health challenge, particularly in resource-limited settings where they are closely tied to poverty and inadequate sanitation. The increasing emergence of drug resistance and the limited accessibility of current therapies highlight the urgent need for novel, safe, and affordable alternatives. Mangifera indica L. (mango), a widely cultivated fruit tree deeply rooted in traditional medicine, has long been used to treat conditions symptomatic of parasitic diseases, including fever, diarrhea, and dysentery. Phytochemical investigations have revealed a rich spectrum of bioactive compounds, notably mangiferin, phenolic compounds and terpenoids, which exhibit antimicrobial, antioxidant, and immunomodulatory activities. This review critically synthesizes evidence on the antiparasitic potential of M. indica against protozoa, such as Plasmodium, Leishmania, Trypanosoma, Toxoplasma gondii, Entamoeba histolytica, and free-living amoebae, as well as helminths. Strongest evidence exists for malaria and helminth infections, where both crude extracts and isolated compounds demonstrated significant activity in vitro and in vivo. Encouraging but limited findings are available for leishmaniasis and trypanosomiasis, while data on toxoplasmosis and amoebiasis remain largely speculative. Variations in efficacy across studies are influenced by plant parts and extraction methods, with ethanolic extracts and mangiferin often showing superior results. Despite promising findings, mechanistic studies, standardized methodologies, toxicological evaluations, and clinical trials are scarce. Future research should focus on elucidating molecular mechanisms, exploring synergistic interactions with existing drugs, and leveraging advanced delivery systems to enhance bioavailability.
A method to remove heavy metals from wastewater by modifying the surface of a PVDF membrane using chitosan and PANi and assessing it using the Hermia model
Shanmuga Sundar Saravanabhavan, Vasantha Palaniappan Kamalakannan, Amudha Thanarasu, Nivetha Marimuthu, Parthiban Devarajan, Vijayan Dhanasingh Sivalinga, Kannan Natarajan, Balasubramanian Natesan
International Journal of Biological Macromolecules, 2025
In vitro and in silico investigations of Propolis-derived phytochemicals as potential inhibitors of Plasmodium falciparum
Dhrubo Ahmed Khan, Md. Nazmul Hasan, Rachasak Boonhok, Suthinee Sungkanu, Yutatirat Singhaboot, Afsana Amin Shorna, Anamul Hasan, Kesinee Chotivanich, Polrat Wilairatana, Abolghasem Siyadatpanah, Roghayeh Norouzi, Imran Sama-ae, Watcharapong Mitsuwan, Alok K. Paul, Maria de Lourdes Pereira, Shanmuga S. Sundar, Tooba Mahboob, Christophe Wiart, Ryan V. Labana, Siriphorn Chimplee, Veeranoot Nissapatorn
Veterinary World, 2025
Background and Aim: Malaria continues to pose a global health challenge, exacerbated by the emergence of drug-resistant strains of Plasmodium falciparum. This study aimed to evaluate the anti-Plasmodium potential of Propolis extracts collected from various Iranian regions and to characterize the molecular interactions of their bioactive phytochemicals with P. falciparum lactate dehydrogenase (PfLDH), a key enzyme in parasite glycolysis. Materials and Methods: The anti-Plasmodium activity of ethanol-extracted Propolis was assessed against P. falciparum NF54 using the SYBR Green I fluorescence assay. Gas chromatography-mass spectrometry (GC-MS) analysis identified major phytochemicals in the most active extract. Molecular docking and 100-ns molecular dynamic (MD) simulations were performed to evaluate the binding affinity and stability of selected compounds (tectochrysin and galangin) against PfLDH in both holo (Protein Data Bank [PDB] ID: 1LDG) and apo (PDB ID: 2X8L) forms. Results: Propolis collected from Kermanshah city exhibited the highest anti-Plasmodium activity (IC50 = 6.69 ± 1.44 μg/mL). GC-MS analysis identified tectochrysin and galangin as major constituents. Molecular docking revealed strong binding affinities of tectochrysin (−7.8 kcal/mol) and galangin (−7.5 kcal/mol) to PfLDH, surpassing the binding energies of standard antimalarial drugs (chloroquine and quinine). MD simulations confirmed the stability of tectochrysin and galangin within the PfLDH active sites, with favorable root mean square deviation, root mean square fluctuation, gyration, solvent-accessible surface area, molecular surface area, and polar surface area profiles, indicating persistent and stable protein-ligand interactions throughout the simulation. Conclusion: The findings support the promising anti-Plasmodium potential of Propolis-derived compounds, particularly tectochrysin and galangin, as novel PfLDH inhibitors. Their potential applicability in transdisciplinary anti-parasitic therapy across human and veterinary medicine warrants further in vivo validation and clinical investigations. Keywords: anti-malarial candidates, galangin, lactate dehydrogenase, molecular docking, molecular dynamics, Plasmodium falciparum, Propolis extract, tectochrysin
Engineering Behavior Assessment of Weak Soil Stabilized Using Amalgamated Geopolymer with Industrial Waste—An Experimental Study
D. Parthiban, D. S. Vijayan, S. Shanmuga Sundar, Arvindan Sivasuriyan
Lecture Notes in Civil Engineering, 2025
Amebicidal and Antiadhesion Activities of Knema retusa Extract Against Acanthamoeba triangularis T4 Genotype on Contact Lenses and Modeling Simulation of Its Main Compound, E2N, Against Acanthamoeba Beta-Tubulin
Watcharapong Mitsuwan, Imran Sama-ae, Suthinee Sangkanu, Dhrubo Ahmed Khan, Partha Biswas, Md. Nazmul Hasan, Julalak Chuprom, Tajudeen O. Jimoh, Christophe Wiart, Masyitah Binti Zulkipli, Nor Hayati Abdullah, Maria de Lourdes Pereira, Sonia M. Rodrigues Oliveira, Shanmuga Sundar Saravanabhavan, Polrat Wilairatana, Tooba Mahboob, Veeranoot Nissapatorn
Scientifica, 2025
Medicinal plants have been used as alternative agents for the treatment of infections. This study aimed to investigate bioactivities of medicinal plant extracts including Knema retusa extract (Kre) against Acanthamoeba triangularis T4 in vitro and in silico. Anti‐Acanthamoeba activities of 44 extracts from 5 plant species were determined. From 44 tested extracts, a chloroform extract of Kre bark showed the strongest anti‐Acanthamoeba activities against both trophozoites and cysts, with MIC values of 32.25 and 62.50 μg/mL, respectively. Then, amebicidal and antiadhesion activities of Kre against A. triangularis were investigated. Kre reduced the growth by 3 logs within 8 h at 4 × MIC. Disruption of the cells with abnormal shapes was observed when trophozoites were treated with Kre. Trophozoites had lost their robust acanthopodia and began to shrink after treatment with Kre. Treated cysts exhibited wall disruption and dramatically showed forms of marked retraction. Treatment of Kre at 1/2 × MIC showed about 87% reduction in the trophozoite adhesion, while treatment at 2 × MIC exhibited a 59% reduction in the trophozoite adhesion to the plastic surface, compared with the control. Furthermore, 1 log cells/mL (90%) of the contact lens adhesive trophozoites were reduced and removed after treatment with Kre. Molecular docking indicated that E2N, the main compound in Kre, exhibited strong binding to the ligand binding sites at β‐tubulin, with a binding energy of −7.01 kcal/mol and an inhibitory constant of 2.43–7.32 μM. E2N generated multiple connections via hydrogen, hydrophobic, ionic, and water bridge bonding and maintained these connections until the simulation finished, facilitating the creation of stable bindings with the β‐tubulin protein as measured by molecular dynamics simulation. These findings suggest that Kre exhibits amebicidal and antiadhesion activities which could be used for the prevention of A. triangularis adhesion to contact lenses.
Effect of Alkaline Activated Cashew Nut Shell Ash in the Stabilization of Weak Clayey Soil—An Experimental Study
Parthiban Devarajan, Dhanasingh Sivalinga Vijayan, Shanmuga Sundar Saravanabhavan, Arvindan Sivasuriyan, Naveen Sankaran, Theodoros Chrysanidis, Zineb Moujoud
Ceramics, 2024
Weak clayey soils in construction are considered problematic due to their high compressibility and low bearing capacity. This study proposes an environmentally friendly replacement for conventional soil stabilizers through the use of geopolymer (GP) containing Cashew Nut Shell Ash (CNSA) to improve soil characteristics. In this study, the CNSAGP was compared with lime-stabilized soil for unconfined compressive strength (UCS), durability, and improved microstructure. The experimental outcomes showed that 9 M + CNSAGP with 4% CNSA provided a UCS of 1900 kPa, which was higher than the lime-stabilized soil (6% lime with 4% CNSA) at 1400 kPa. Durability test results revealed that the CNSAGP-treated sample had better protection against water damage with a strength loss of about 18%, while the lime-treated sample had a strength loss of about 25%. Thermal stability analysis showed that CNSAGP had lower LOI values compared to lime-stabilized samples (0.17% at 900 °C), which indicates CNSAGP’s heat resistance. Microstructure analysis revealed that CNSAGP-stabilized soil was less porous, the microstructure being denser because of reactions of aluminosilicate and pozzolanic activity. Moreover, it affected the soil’s alkalinity, making it better, and improved Atterberg limits, which affected the plasticity and workability. These findings show that CNSAGP is a long-lasting and eco-friendly means of soil stabilization with higher strength, thermal stability, and durability than traditional methods and can be used in engineering.
Anti-adherent effects of Rhizophora apiculata bark and leaf extracts and computational prediction of the effects of its compound on β-tubulin interaction in Acanthamoeba triangularis genotype 4
Siriphorn Chimplee, Imran Sama-ae, Suthinee Sangkanu, Watcharapong Mitsuwan, Julalak Chuprom, Rachasak Boonhok, Dhrubo Ahmed Khan, Partha Biswas, Md Nazmul Hasan, Hazel Anne Tabo, Cristina C. Salibay, Polrat Wilairatana, Maria L. Pereira, Muhammad Nawaz, Ragini Bodade, Shanmuga S. Sundar, Alok K. Paul, Veeranoot Nissapatorn
Veterinary World, 2024
Background and Aim: Acanthamoeba, an opportunistic protozoan, exists widely in natural sources and can cause infections in humans and animals. The absence of effective monotherapy after the initial infection leads to chronic disease and recurrence. Tubulin protein is a vital target for design-targeted drug discovery. Anti-tubulin drugs are also used to treat Acanthamoeba infection, although resistance to these drugs has been observed. Therefore, it is necessary to identify a new targeted drug for Acanthamoeba infection. Therefore, this study aimed to assess the in vitro activity of ethanol extracts of Rhizophora apiculata extracts (RAE) against Acanthamoeba spp. and to predict its chemical compound on β-tubulin interaction. Materials and Methods: Acanthamoeba, an opportunistic protozoan, exists widely in natural sources and can cause infections in humans and animals. The absence of effective monotherapy after the initial infection leads to chronic disease and recurrence. Tubulin protein is a vital target for design-targeted drug discovery. Anti-tubulin drugs are also used to treat Acanthamoeba infection, although resistance to these drugs has been observed. Therefore, it is necessary to identify a new targeted drug for Acanthamoeba infection. Therefore, this study aimed to assess the in vitro activity of ethanol extracts of Rhizophora apiculata extracts (RAE) against Acanthamoeba spp. and to predict its chemical compound on β-tubulin interaction. Results: The results revealed that A. triangularis and A. polyphaga trophozoites had the highest inhibition at 90% at a MIC of 8 mg/mL after treatment with RALE and RABE, respectively, at 24 h. Those MPC values were exhibited at 16 mg/mL against A. triangularis trophozoites. In addition, both extracts inhibited the adhesive properties of all Acanthamoeba approximately 80%–90% at 4 mg/ mL, as well as adherent structural acanthopodia loss. MCC was 0.25 mg/mL, provided to be harmless to mammalian cells. GC-MS analysis supported that 8 and 11 major phytochemicals were from RABE and RALE, respectively. Molecular docking and molecular dynamics demonstrated that Acanthamoeba-β-tubulin exhibited potent root-mean-square deviation, root mean square fluctuation, and binding free energy values with clionasterol (from RABE and RALE) and stigmasterol (from RALE). Based on our results, ethanolic RABE and RALE exhibited anti-Acanthamoeba activity in reducing adhesion. In silico showed that promising clionasterol and stigmasterol interacted with a targeting β-tubulin. Conclusion: The RABE and RALE exhibited a potential adherent effect on A. triangularis, low toxicity, and the clionasterol and stigmasterol in RABE and RALE predicted to interact the targeted β-tubulin. These agents may be used as alternative therapeutic agents in the management of disease using a sustainable one-heath approach. Keywords: Acanthamoeba triangularis, anti-adherent activity, molecular docking, molecular dynamic simulation, Rhizophora, tubulin.
Nano-materials in Drug Delivery Systems for Oral Cancer Treatment: A Review
Texila International Journal of Public Health, 2024
Oral cancer is a serious health concern requiring target-specific treatment strategies due to its high rates of morbidity and mortality.Early detection of cancer cells considerably improves prognosis and treatment outcomes.Recently, nanomaterials have opened a world of intriguing new possibilities for cancer diagnosis and therapy by providing creative ways to enhance patients' quality of life.Furthermore, modified nanoparticles use specially designed moieties to target cancer cells more precisely.Drug delivery methods could reduce side effects and significantly improve oral cancer treatment efficacy.In addition, polymer-based drug delivery methods are designed to release drugs gradually and in a controlled way.In addition, the combination therapy with a drug delivery system leads to a synergetic effect are also discussed.
Examination of hybrid electrode material for energy storage device supercapacitor under various electrolytes
Joselene Suzan Jennifer Patrick, Niranjana Subrayapillai Ramakrishna, Muthupandi Sankar, Madhavan Joseph, Victor Antony Raj Moses, Shanmuga Sundar Saravanabhavan, Muthukrishnaraj Appusamy, Manikandan Ayyar
Carbon Letters, 2024
In vitro study on the inflammatory response of chitosan nanoparticles as a potential siRNA carrier targeting towards osteosarcoma cells
Sundar S. Shanmuga, Kannan Natarajan, Sarang Zsolt, Lakshminarayanan Srimathi Priya, Manikandan Ayyar, Sasikala Anboo, Veeranoot Nissapatorn, Narendranath Jonna, Kamalakannan Vasanthapalaniappan, Rajavelu Packirisamy, Karma Gyurmey Dolma
Zeitschrift Fur Physikalische Chemie, 2024
Bioactivity, hemocompatibility, and inflammatory response of calcium incorporated sulfonated polyether ether ketone on mouse-derived bone marrow cells
Shanmuga Sundar Saravanabhavan, Prabhu Narayanaswamy Venkatesan, Narendranath Jonna, Kamalakannan Vasantha Palaniappan, Zsolt Sarang, Balasubramanian Natesan, Consolato M. Sergi
Bioscience Reports, 2024
Inhibitory and anti-adherent effects of Piper betle L. leaf extract against Acanthamoeba triangularis in co-infection with Staphylococcus aureus and Pseudomonas aeruginosa: A sustainable one-health approach
Pattamaporn Kwankaew, Suthinee Sangkanu, Watcharapong Mitsuwan, Rachasak Boonhok, Udom Lao-On, Hazel L. Tabo, Tooba Mahboob, Maria de Lourdes Pereira, Jitbanjong Tangpong, Shanmuga S. Sundar, Christophe Wiart, Veeranoot Nissapatorn
Veterinary World, 2024
Preparation and evaluation of physicochemical studies of novel natural cellulose microfibril (CMF) reinforced poly (sodium acrylate) hydrogel
Nithya Ramasamy, Anbudayanidhi Sivalingam, Shanmuga Sundar Saravanabhavan, Kavitha Nagarasampatti Palani, Balasubramanian Natesan
Carbon Letters, 2024
Preparation and evaluation of a niosomal delivery system containing G. mangostana extract and study of its anti-Acanthamoeba activity
Suthinee Sangkana, Komgrit Eawsakul, Tassanee Ongtanasup, Rachasak Boonhok, Watcharapong Mitsuwan, Siriphorn Chimplee, Alok K. Paul, Shanmuga Sundar Saravanabhavan, Tooba Mahboob, Muhammad Nawaz, Maria L. Pereira, Polrat Wilairatana, Christophe Wiart, Veeranoot Nissapatorn
Nanoscale Advances, 2024
The Effect of Microbiome Exchange on Humans and Animals
Karma G. Dolma, Sundar S. Shanmuga, Chamma Gupta, Veeranoot Nissapatorn
Microbial Ecology Microbiomes Viromes and Biofilms, 2024
Microbiomes and Viromes in Infection
Sundar S. Shanmuga, N. Kannan, R. Devika, Karma Gyurmey Dolma, Veeranoot Nissapatorn
Microbial Ecology Microbiomes Viromes and Biofilms, 2024
Comparative efficacy of Knema retusa extract delivery via PEG-b-PCL, niosome, and their combination against Acanthamoeba triangularis genotype T4: characterization, inhibition, anti-adhesion, and cytotoxic activity
Siriphorn Chimplee, Watcharapong Mitsuwan, Masyitah Zulkifli, Komgrit Eawsakul, Tassanee Ongtanasup, Suthinee Sangkanu, Tooba Mahboob, Sonia M.R. Oliveira, Christophe Wiart, Siva Ramamoorthy, Maria de Lourdes Pereira, Shanmuga Sundar Saravanabhavan, Polrat Wilairatana, Veeranoot Nissapatorn
Peerj, 2024
Electrochemical recovery of hydrogen and elemental sulfur from hydrogen sulfide gas by two-cell system
J. Narendranath, J. Manokaran, S. Shanmuga Sundar, R. Muruganantham, Ahmed Al Shoaibi, C. Srinivasakannan, N. Balasubramanian
Energy Sources Part A Recovery Utilization and Environmental Effects, 2023
Green synthesis of silver nanoparticles using Ocimum sanctum Linn. and its antibacterial activity against multidrug resistant Acinetobacter baumannii
Deepan Gautam, Karma Gurmey Dolma, Bidita Khandelwal, Madhu Gupta, Meghna Singh, Tooba Mahboob, Anil Teotia, Prasad Thota, Jaydeep Bhattacharya, Ramesh Goyal, Sonia M.R. Oliveira, Maria de Lourdes Pereira, Christophe Wiart, Polrat Wilairatana, Komgrit Eawsakul, Mohammed Rahmatullah, Shanmuga Sundar Saravanabhavan, Veeranoot Nissapatorn
Peerj, 2023
A study on novel coupled membrane bioreactor with electro oxidation for biofouling reduction
Kamalakannan Vasanthapalaniappan, Kavitha Palani, Shanmuga Sundar Saravanabhavan, Narendranath Jonna, Maharaja Pounsamy, Kannan Natarajan, Yun Suk Huh, Balasubramanian Natesan
Environmental Engineering Research, 2021
Physiochemical characterization and toxicity assessment of colloidal mercuric formulation–‘Sivanar amirtham’
Kannan N, Shanmuga Sundar S, Balaji S, Anil Kumar NV, Balasubramanian N
Colloids and Surfaces B Biointerfaces, 2021
Immuno-MALDI MS dataset for improved detection of HCVcoreAg in sera
Anna L. Kaysheva, Tatyana O. Pleshakova, Alexander A. Stepanov, Vadim S. Ziborov, Shanmuga S. Saravanabhavan, Balasubramanian Natesan, Alexander I. Archakov, Yurii D. Ivanov
Data in Brief, 2019
Graphene oxide functionalized with chitosan based nanoparticles as a carrier of siRNA in regulating Bcl-2 expression on Saos-2 & MG-63 cancer cells and its inflammatory response on bone marrow derived cells from mice
Shanmuga Sundar Saravanabhavan, Muruganantham Rethinasabapathy, Sarang Zsolt, Aravind Bhat Kalambettu, Sundaravadivel Elumalai, Manokaran Janakiraman, Yun Suk Huh, Balasubramanian Natesan
Materials Science and Engineering C, 2019
Correction: Study on the inflammatory response of PMMA/polystyrene/silica nanocomposite membranes for drug delivery and dental applications(PLoS ONE (2019) 14:3 (e0209948) DOI: 10.1371/journal.pone.0209948)
S. Shanmuga Sundar, N. Kannan, E. Sundaravadivel, Sarang Zsolt, K. S. Mukunthan, J. Manokaran, J. Narendranath, V. P. Kamalakannan, N. P. Kavitha, N. V. Prabhu, N. Balasubramanian
Plos One, 2019
Study on the inflammatory response of PMMA/polystyrene/silica nanocomposite membranes for drug delivery and dental applications
S. Shanmugasundar, N. Kannan, E. Sundaravadivel, Sarang Zsolt, K. S. Mukunthan, J. Manokaran, J. Narendranath, V. P. Kamalakannan, P. Kavitha, V. Prabhu, N. Balasubramanian
Plos One, 2019
Development of sequential batch ozonated adsorptive membrane bioreactor to mitigate fouling with reduced energy consumption
Kavitha Nagarasampatti Palani, Darshini Saravanan, Kamalakannan Vasantha Palaniappan, Shanmuga Sundar, N. Balasubramanian
Korean Journal of Chemical Engineering, 2019
Correction: Physiochemical characterization and cytotoxicity evaluation of mercury-based formulation for the development of anticancer therapeuticals (PLoS ONE (2018) 13:4 (e0195800) DOI: 10.1371/journal.pone.0195800)
N Kannan, S Shanmuga Sundar, S Balaji, Arul Amuthan, NV Anil Kumar, N Balasubramanian
Plos One, 2018
Physiochemical characterization and cytotoxicity evaluation of mercury-based formulation for the development of anticancer therapeuticals
Kannan N, Shanmuga Sundar S, Balaji S, Arul Amuthan, Anil Kumar NV, Balasubramanian N
Plos One, 2018
In vivo studies of Sulphonated polyether ether Ketone based composite bone graft materials
Trends in Biomaterials and Artificial Organs, 2014
Evaluating triboelectric properties of polymer films: An incipient appliance and case studies
Saravanabhavan Sundar, Kalambettu Aravind, Rethinasababathy Muruganantham, Dharmalingam Sangeetha
Recent Patents on Materials Science, 2014
Fabrication of polysulphone/hydroxyapatite nanofiber composite implant and evaluation of their in vitro bioactivity and biocompatibility towards the post-surgical therapy of gastric cancer
Shanmuga Sundar Saravanabhavan, Sangeetha Dharmalingam
Chemical Engineering Journal, 2013
Fabrication of chitosan/TPP nanoparticles as a carrier towards the treatment of cancer
International Journal of Drug Delivery, 2013
Prolonged amoxicillin release kinetics and biocompatibility using Chitosan/PVA blend membranes in-vitro
Trends in Biomaterials and Artificial Organs, 2012
Fabrication and evaluation of electrospun collagen/poly(N-isopropyl acrylamide)/chitosan mat as blood-contacting biomaterials for drug delivery
Saravanabhavan Shanmuga Sundar, Dharmalingam Sangeetha
Journal of Materials Science Materials in Medicine, 2012
Investigation on sulphonated PEEK beads for drug delivery, bioactivity and tissue engineering applications
Saravanabhavan Shanmuga Sundar, Dharmalingam Sangeetha
Journal of Materials Science, 2012

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