Animal Science and Zoology, Endocrinology, General Biochemistry, Genetics and Molecular Biology, Health, Toxicology and Mutagenesis
1
Scopus Publications
211
Scholar Citations
6
Scholar h-index
6
Scholar i10-index
Scopus Publications
Oxidative stress biomarkers in the freshwater fish, Heteropneustes fossilis (bloch) exposed to sodium fluoride: Antioxidant Defense and role of ascorbic acid ShivShankar Yadav, Rajesh Kumar, Puneet Khare, Madhu Tripathi Toxicology International, 2015 The present study highlights fluoride -induced toxicity and the protective role of ascorbic acid in the liver and ovary of freshwater fish, Heteropneustis fossilis. The fish specimens were exposed to different concentrations (35 mg F/L and 70 mg F/L) of fluoride. Parameters related to oxidative stress were studied at the end of the experiment. The biomarkers selected for the study were thiobarbituric acid reactive substances for assessing the extent of lipid peroxidation (LPO) and antioxidant defense system such as reduced glutathione (GSH), superoxide dismutase (SOD) catalase (CAT) glutathione peroxidase (GPx), and glutathione S-transferase (GST) activities. The fluoride exposure significantly elevated the level of LPO, CAT, SOD, and GST in the tissues of treated group as well as modulated the activities of GSH and level of GPx after exposure as compared to the control. A significant decrease in GPx activity was found in these tissues suggesting that fluoride exposure increases the level of free radical, as well as CAT activity. Pre- and post treatment with ascorbic acid decreased the LPO, SOD, CAT, GST level, and increased GSH, GPx levels in the liver and ovary.
RECENT SCHOLAR PUBLICATIONS
Cadmium Toxicity Induced Changes on Antioxidative Enzymes Level in Fresh Water Catfish Channa Punctatus (Bloch) MT Rajesh Kumar, Shiv Shankar Yadav Qeios, 1-18 , 2024 2024 Citations: 2
Role of vitamin C on hormonal and pathological changes in Heteropneustes fossilis (Bloch) due to exposure to sodium fluoride SSYM Tripathi Indian Journal of Experimental Biology 58 (10), 706-713 , 2020 2020 Citations: 4
GC-MS ANALYSIS OF BIO-ACTIVE COMPOUNDS IN METHANOLIC EXTRACT OF ZIZIPHUS MAURITIANA FRUIT VSLKD Pankaj Kushwaha, Shiv Shankar Yadav International Journal of Pharmaceutical Sciences and Research 10 (6), 2911-2916 , 2019 2019 Citations: 28
PHYTOCHEMICAL SCREENING AND GC-MS STUDIES OF THE METHANOLIC EXTRACT OF TRIDAX PROCUMBENS P Kushwaha, SS Yadav, V Singh, LK Dwivedi International Journal of Pharmaceutical Sciences and Research 10 (5), 2492-2496 , 2019 2019 Citations: 28
Oxidative stress biomarkers and histological study in kidney of Heteropneustes fossilis (Bloch) treated with sodium fluoride exposure. SSYRKM Tripathi International Journal of Recent Scientific Research 8 (7), 18594-18601 , 2017 2017
CARBON SEQUESTRATION: ASSESSMENT AND APPLICATION-A REVIEW NGAA Jaspal Singh*, Puneet Khare, Shivshanker Yadav European Journal of Pharmaceutical and Medical Research 4 (5), 220-222 , 2017 2017 Citations: 4
Biochemical changes of antioxidants enzymes in cat fish (Heteropneustis fossilis) bloch after fluoride exposure YS Shankar, V Pankaj, T Madhu Int J of Recent Scientific Res. 6 (2): 2859 2862 , 2015 2015 Citations: 3
Oxidative Stress Biomarkers in the Freshwater Fish, Heteropneustes fossilis (Bloch) Exposed to Sodium Fluoride: Antioxidant Defense and Role of Ascorbic Acid MT Shiv Shankar Yadav, Rajesh Kumar, Puneet Khare Toxicology International 22 (1), 71-76 , 2015 2015 Citations: 79
Effects of fluoride exposure on some enzymatic and histopathological changes in the liver of Heteropneustes fossilis (Bloch). MT Shiv Shankar Yadav, Rajesh Kumar International Journal of Fauna and Biological Studies 1 (5), 80-84 , 2014 2014 Citations: 16
Studies on length–weight relationship of seven commercially important freshwater fish species of Gomti River Lucknow (UP) India R Kumar, SS Yadav, M Tripathi 2014 Citations: 22
Generation of cDNA clones from Tricomes specific cDNA library of Mentha arvensis PKSSD Rajesh Kumar, Shiv S Yadav Pharma Science Monitor An International Journal of Pharmaceutical Sciences … , 2013 2013
Molecular Markers of Aromatic and Medicinal Plants: A Review MT Rajesh Kumar, Shiv S Yadav, Shiv K Mishra, Anjani Pharma Science Monitor An International Journal of Pharmaceutical Sciences … , 2013 2013
To determine the quality of potable water in Kanpur city with special reference to fluoride concentration SSMT Pankaj Verma, Sarad Chand Srivastava, Shiv Shankar Yadav Poll Res. 32 ((4)), 117-121 , 2013 2013
Assessment of antiarthritic and immunomdulatory properties of lactobacillus casei in collagen induced arthritis(CIA) experimental model SSYA Sarika Amdekar, Vinod Singh, Rambir Sehrawat International journal of Integrative Biology. 9 ((3)), 141-147 , 2010 2010 Citations: 4
Variation in serum lipids & liver function markers in lindane exposed female wistar rats: attenuating effect of curcumin, vitamin C &vitamin E. SSAR Poonam Sharma ASIAN J.EXP.BIOL.SCI 1 ((2)), 440-444 , 2010 2010 Citations: 21
MOST CITED SCHOLAR PUBLICATIONS
Oxidative Stress Biomarkers in the Freshwater Fish, Heteropneustes fossilis (Bloch) Exposed to Sodium Fluoride: Antioxidant Defense and Role of Ascorbic Acid MT Shiv Shankar Yadav, Rajesh Kumar, Puneet Khare Toxicology International 22 (1), 71-76 , 2015 2015 Citations: 79
GC-MS ANALYSIS OF BIO-ACTIVE COMPOUNDS IN METHANOLIC EXTRACT OF ZIZIPHUS MAURITIANA FRUIT VSLKD Pankaj Kushwaha, Shiv Shankar Yadav International Journal of Pharmaceutical Sciences and Research 10 (6), 2911-2916 , 2019 2019 Citations: 28
PHYTOCHEMICAL SCREENING AND GC-MS STUDIES OF THE METHANOLIC EXTRACT OF TRIDAX PROCUMBENS P Kushwaha, SS Yadav, V Singh, LK Dwivedi International Journal of Pharmaceutical Sciences and Research 10 (5), 2492-2496 , 2019 2019 Citations: 28
Studies on length–weight relationship of seven commercially important freshwater fish species of Gomti River Lucknow (UP) India R Kumar, SS Yadav, M Tripathi 2014 Citations: 22
Variation in serum lipids & liver function markers in lindane exposed female wistar rats: attenuating effect of curcumin, vitamin C &vitamin E. SSAR Poonam Sharma ASIAN J.EXP.BIOL.SCI 1 ((2)), 440-444 , 2010 2010 Citations: 21
Effects of fluoride exposure on some enzymatic and histopathological changes in the liver of Heteropneustes fossilis (Bloch). MT Shiv Shankar Yadav, Rajesh Kumar International Journal of Fauna and Biological Studies 1 (5), 80-84 , 2014 2014 Citations: 16
Role of vitamin C on hormonal and pathological changes in Heteropneustes fossilis (Bloch) due to exposure to sodium fluoride SSYM Tripathi Indian Journal of Experimental Biology 58 (10), 706-713 , 2020 2020 Citations: 4
CARBON SEQUESTRATION: ASSESSMENT AND APPLICATION-A REVIEW NGAA Jaspal Singh*, Puneet Khare, Shivshanker Yadav European Journal of Pharmaceutical and Medical Research 4 (5), 220-222 , 2017 2017 Citations: 4
Assessment of antiarthritic and immunomdulatory properties of lactobacillus casei in collagen induced arthritis(CIA) experimental model SSYA Sarika Amdekar, Vinod Singh, Rambir Sehrawat International journal of Integrative Biology. 9 ((3)), 141-147 , 2010 2010 Citations: 4
Biochemical changes of antioxidants enzymes in cat fish (Heteropneustis fossilis) bloch after fluoride exposure YS Shankar, V Pankaj, T Madhu Int J of Recent Scientific Res. 6 (2): 2859 2862 , 2015 2015 Citations: 3
Cadmium Toxicity Induced Changes on Antioxidative Enzymes Level in Fresh Water Catfish Channa Punctatus (Bloch) MT Rajesh Kumar, Shiv Shankar Yadav Qeios, 1-18 , 2024 2024 Citations: 2
Oxidative stress biomarkers and histological study in kidney of Heteropneustes fossilis (Bloch) treated with sodium fluoride exposure. SSYRKM Tripathi International Journal of Recent Scientific Research 8 (7), 18594-18601 , 2017 2017
Generation of cDNA clones from Tricomes specific cDNA library of Mentha arvensis PKSSD Rajesh Kumar, Shiv S Yadav Pharma Science Monitor An International Journal of Pharmaceutical Sciences … , 2013 2013
Molecular Markers of Aromatic and Medicinal Plants: A Review MT Rajesh Kumar, Shiv S Yadav, Shiv K Mishra, Anjani Pharma Science Monitor An International Journal of Pharmaceutical Sciences … , 2013 2013
To determine the quality of potable water in Kanpur city with special reference to fluoride concentration SSMT Pankaj Verma, Sarad Chand Srivastava, Shiv Shankar Yadav Poll Res. 32 ((4)), 117-121 , 2013 2013