Dr Sathish Kumar Konidala

Scopus Publications

Development and validation of an LC–MS/MS method for Lazertinib in rat plasma using SFOD microextraction with pharmacokinetic application
Rajesh Guntupalli, Panchumarthy Ravisankar, Sathish Kumar Konidala
Microchemical Journal, 2026
A Robust and Sustainable HPLC Refractive Index Method Using Box–Behnken Design for Simultaneous Determination of Glycerin and Propylene Glycol
Prasanth Katakam, Bharat Kumar Tripuramallu, Satish Kumar Konidala, Ravi Kumar Pedapati, Kishore Rapolu, Srinivas Torati
Separation Science Plus, 2026
Glycerin (Gly) and propylene glycol (PG) are widely used excipients in pharmaceutical formulations, and their accurate and reliable quantification is essential for quality control (QC). The present study describes the development, optimization, and validation of a robust, sustainable, and environmentally conscious high‐performance liquid chromatography (HPLC) refractive index method for the simultaneous determination of glycerin and PG using a quality‐by‐design (QbD) approach. The optimized chromatographic conditions employed an Inertsil ODS‐3, 5 µm, 4.6 mm × 250 mm column with a mobile phase of water and methanol (90:10, v/v), flow rate of 0.5 mL/min, and column temperature of 40°C. The method was validated in accordance with International Council for Harmonization (ICH) guidelines. Accuracy results were found to be 99.1%–99.9% for Gly and 99.7%–99.9% for PG. Precision results were found Gly 0.3% and PG 0.4% relative standard deviation. Correlation coefficient ( r 2 ) was obtained >0.998 for two components. Analytical solutions are stable for 67 h at ambient conditions. The environmental sustainability of the method was assessed using AGREE, AGREEprep, Green Analytical Procedure Index (GAPI), ComplexGAPI, and Blue Applicability Grade Index (BAGI) tools, indicating a favorable greenness profile due to low organic solvent usage and simple sample preparation. The proposed method is reliable, cost‐effective, and suitable for routine QC applications while aligning with green analytical chemistry principles.
MULTITARGET NEUROPROTECTIVE POTENTIAL OF MYRISTICA MALABARICA AND SESBANIA GRANDIFLORA: AN INTEGRATED HR-LCMS, IN VITRO AND MOLECULAR DOCKING APPROACH IN DIABETES-ASSOCIATED COGNITIVE DYSFUNCTION
Jagadeeshwar Kolguri, Risy Namratha Jamullamudi, Nallapaty Srilakshmi, Sathish Kumar Konidala
Genetics and Molecular Research, 2026
Diabetes-associated cognitive decline (DACD) is a progressive neurodegenerative condition characterized by impairments in learning, memory, and executive function, primarily driven by chronic hyperglycemia-induced oxidative stress and neuroinflammatory pathways. Despite the availability of therapies, effective multitarget interventions remain limited. The present study was employed for an integrated experimental and computational approach to evaluate the hypothesis that methanolic bark extracts of Myristica malabarica and Sesbania grandiflora possess multifunctional neuroprotective properties capable of modulating multiple molecular targets involved in DACD. Phytochemical characterization was performed by quantification of total phenolic and flavonoid contents, followed by HR-LCMS for metabolite profiling. Identified phytoconstituents were subjected to in silico pharmacokinetic evaluation (SwissADME) to determine drug-likeness, gastrointestinal absorption, and blood–brain barrier permeability. Of all, twelve compounds satisfying ADME criteria were selected for molecular docking studies using AutoDock Vina against key DACD-related targets, including acetylcholinesterase (AChE), monoamine oxidase-B (MAO-B), cyclooxygenase-2 (COX-2), glycogen synthase kinase-3β (GSK-3β), and the Keap1–Nrf2 complex. Additionally, in vitro antioxidant and enzyme inhibition assays were conducted. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test, with significance set at p < 0.05. HR-LCMS analysis identified multiple bioactive phytoconstituents, of which twelve demonstrated favorable pharmacokinetic properties, including high gastrointestinal absorption and blood–brain barrier permeability. Docking studies revealed that compounds M4(Androsta-4,9(11)-diene-3,17-dione), M8(Pirenperone), and M9(Drotaverine) exhibited strong binding affinities across multiple targets, with docking scores comparable to or exceeding standard drugs, donepezil and selegiline. In vitro assays demonstrated significant antioxidant and enzyme inhibitory activities (p < 0.01), including oxidative stress marker reduction and modulation of key enzymes associated with neurodegeneration and inflammation. The findings confirm that M. malabarica and S. grandiflora exhibit multifunctional and multitarget neuroprotective effects, supporting their potential as promising phytotherapeutic candidates for the management of DACD. Further in vivo validation, mechanistic studies, and formulation development are warranted to facilitate clinical translation.
A Robust LC-MS/MS Bioanalytical Strategy for Simultaneous Quantification of Tramadol HCl and Dexketoprofen Trometamol and Its Use in Pharmacokinetic Studies
Adusumalli Srinivasa Rao, P. Bangaraiah, Sathish Kumar Konidala
Biomedical Chromatography, 2026
This study reports the first bioanalytical method for simultaneous estimation of Tramadol HCl and dexketoprofen trometamol in rat plasma using Tapentadol as an internal standard. A validated LC‐MS/MS method was developed following USFDA guidelines. Analytes were extracted from plasma by protein precipitation technique using acetonitrile. Chromatographic separation was achieved on a Waters Symmetry Shield RP‐18 column (250 × 4.6 mm, 5 μm) with an isocratic mobile phase of acetonitrile and 0.1% formic acid in HPLC grade water (30:70 v/v) at a flow rate of 1.0 mL/min, yielding a 7‐min runtime. Detection was performed using electrospray ionization with ion transitions of m/z 222.3398 → 70.0307 for Tapentadol, m/z 264.4351 → 96.4527 for Tramadol HCl, and m/z 376.4239 → 100.4520 for dexketoprofen trometamol. The method showed good accuracy, with mean recoveries of 92.79%–98.15% for Tramadol HCl and 91.78%–98.37% for dexketoprofen trometamol. Excellent linearity was obtained, with r 2 values of 0.99983 (22.5–900 ng/mL) and 0.99963 (7.5–300 ng/mL), respectively. All validation parameters met acceptable criteria. The method is suitable for evaluating pharmacokinetic parameters that indicate drug efficacy and safety.
Network Pharmacology and Molecular Docking-Based in Silico Investigation of Anti-Atherosclerotic Phytoactives From Annona Reticulata and Ocimum Basilicum
Premi Gelam, Ramayyappa Muddala, Siva Satya Narayana Kaipu, Sravani Boyapati, Rama Rao Vadapalli, Sathish Kumar Konidala, Kamma Harsha Sri
Chemistryselect, 2026
Atherosclerosis (AS) remains a leading cause of cardiovascular morbidity and mortality, demanding the identification of novel and safer therapeutic strategies. While Ocimum basilicum (basil) and Annona reticulata (custard apple) have been traditionally reported to possess cardio protective effects, the underlying molecular mechanisms are not fully understood. In this study, we employed an integrative computational framework combining network pharmacology (NP), ADMET screening, molecular docking (MD), and pathway enrichment analysis to explore the multi‐target anti‐atherosclerotic potential of their phytoconstituents. Seven bioactive compounds with favorable drug‐likeness and pharmacokinetic properties were identified, of which four displayed strong binding affinities toward key targets such as HSP90AA1, STAT3, NF‐κB, and IL‐6. Gene Ontology (GO) and KEGG enrichment revealed their involvement in inflammatory signaling, oxidative stress regulation, and immune modulation pathways, central to AS progression. Toxicity predictions further supported their drug‐likeness and safety profile. Collectively, this systems‐level analysis provides mechanistic insights into the therapeutic potential of O. basilicum and A. reticulate bioactives and highlights their promise as leads for anti‐atherosclerotic drug development.
Validated LC-MS/MS Method for Quantification and Pharmacokinetic Analysis of Talazoparib and Enzalutamide in Rats
Rajesh Guntupalli, Panchumarthy Ravisankar, Sathish Kumar Konidala
Biomedical Chromatography, 2026
The FDA has approved Talazoparib and Enzalutamide for metastatic castration‐resistant prostate cancer (mCRPC) with homologous recombination repair (HRR) gene mutations, based on the TALAPRO‐2 Phase 3 trial. This study developed and validated an LC‐MS/MS method for simultaneous quantification of Talazoparib and Enzalutamide in rat plasma using Apalutamide as the internal standard. Chromatographic separation was achieved with a 70:30 (v/v) acetonitrile–0.1% formic acid system, 10 min runtime, and 1.0 mL/min flow rate. Retention times were 4.13 min (Talazoparib), 5.31 min (Enzalutamide), and 7.89 min (Apalutamide). Detection was performed in positive ionization mode using MRM transitions: m / z 381.35 → 240.56, 465.44 → 305.24, and 478.44 → 285.10, respectively. The method was linear over 0.05–2 ng/mL for Talazoparib and 4–160 ng/mL for Enzalutamide ( r 2 > 0.999). Accuracy and precision were within ±15%–20%, and recovery exceeded 98%. In pharmacokinetic studies on male Wistar rats, Talazoparib showed a C max of 0.88 ng/mL at 3 h and an AUC 0− t of 20 ng·h/mL, while Enzalutamide exhibited a C max of 76.18 ng/mL at 1 h and an AUC 0− t of 1702 ng·h/mL; both had 24 h half‐lives. The validated method enables sensitive, rapid, and reliable bioanalysis for preclinical pharmacokinetic evaluation.
Novel quinoline-4-thiazolidinone derivatives as anticancer agents targeting the biological macromolecular protein-EGFR tyrosine kinase with dual anticancer and antioxidant activities
Sathish Kumar Konidala, Govinda Rao Kamala, Richie R Bhandare, Afzal Basha Shaik
Journal of Molecular Structure, 2026
Simultaneous quantification of linezolid and pretomanid in BALB/c mice plasma using a validated LC-MS/MS method: Application to pharmacokinetic and lung distribution studies
S. Siva Shanmugam, Sathish Kumar Konidala, S. Narayanan, R.K. Shandil
Acta Chromatographica, 2026
A sensitive and selective LC–MS/MS method was developed and validated for the simultaneous quantification of pretomanid and linezolid in BALB/c mouse plasma and lung tissue in accordance with ICH M10 bioanalytical guidelines. Chromatographic separation was achieved on a C18 column with gradient elution using methanol and 0.1% formic acid in water. The method demonstrated linearity ( r 2 > 0.995), accuracy, precision, and recovery within the validated range of 10–20,000 ng mL −1 , without significant matrix effect. Stability under various storage and handling conditions was also confirmed. The validated assay was successfully applied to a pharmacokinetic study using a sparse sampling design, demonstrating reliable quantification of both analytes in plasma and lung tissue and confirming the applicability of the method to preclinical bioanalysis. The developed method provides a robust and validated analytical platform for the simultaneous determination of co-administered anti-tuberculosis agents and is suitable for future pharmacokinetic and tissue distribution studies in preclinical models.
Development of a New Validated RP-HPLC Method for Simultaneous Estimation and Stability Study of Tegafur, Gimeracil and Oteracil in Combined Dosage Form
Panchumarthy Ravisankar, Sathish Kumar Konidala, Kamma Harsha Sri, Chaitanya Sucharitha Kolakaluri, Munnangi Mukkanti Eswarudu, Venkata Prasad Rao Chinni, Srinivasa Babu Puttagunta
Indian Journal of Pharmaceutical Education and Research, 2026
Quantification of Belzutifan in Biological Samples: LC–MS/MS Method Validation and Pharmacokinetic Study in Rats
Kamma Harsha Sri, Panchumarthy Ravisankar, Sathish Kumar Konidala, Srinivasa Babu Puttagunta
Biomedical Chromatography, 2025
Belzutifan, an inhibitor of hypoxia inducible factor‐2α, is used to treat cancer associated with von Hippel Lindau disease. The quality control and pharmacokinetic study of this drug is crucial for effective chemotherapy. Since no bio‐analytical method has been reported, this work aimed to develop an LC–MS/MS technique for the determination of belzutifan and its application for pharmacokinetic profiling in rat plasma. Belzutifan and apalutamide (IS) were quantified on a symmetry shield (150 × 4.6 mm, 3.5 μm) column using acetonitrile and buffer (30:70% v/v) as the mobile phase, with a run time of 7 min. The spiked samples and quality controls were extracted with an optimized protein precipitation technique. Belzutifan and IS were quantified in MRM mode. The validation of the method in compliance with the US FDA's guidelines was performed. The analyte and IS were quantified at m/z 384.3422 → 311.4205 and 478.4154 → 341.1629, respectively. The results indicate linearity between 5 and 100 ng/mL concentration with r2 = 0.9997, which proved to be accurate with % recovery between 95.0% and 97.98%, along with other essential metrics within the accepted limits. The pharmacokinetic study demonstrates that the established LC–MS/MS method accurately quantifies the drugs in rat plasma and might be useful for routine quantification of belzutifan in biological matrices.
IN VIVO AND IN SILICO ANTI-ATHEROSCLEROTIC ACTIVITY OF ETHANOLIC LEAVES EXTRACT OF OCIMUM BASILICUM AND ANNONA RETICULATE
, Premi Gelam, Rama R Vadapalli, , Sathish K. Konidala, , Ramayyappa Muddala, , Brahmaiah Bonthagarala, , Geethika V. R. Samineni, , Mohammed Shakir, , Mounica R. Meka, , Eswari Singampalli, , Raveendra B. Gudimetla, and
Indian Drugs, 2025
Simultaneous Quantification of Multi-Class Antimicrobials in Chicken Kidney and Liver by New Validated UPLC-MS/MS Method
Siva Shanmugam S, Sathish Kumar Konidala, Shridhar Narayanan, Shandil Rk
Hacettepe University Journal of the Faculty of Pharmacy, 2025
Quantification of Vactosertib an Inhibitor of TGFBR1 by LC–MS/MS in Rat Plasma and Its Pharmacokinetic Profiling
Rajesh Kumar Boggavarapu, Jithendra Chimakurthy, Sathish Kumar Konidala
Biomedical Chromatography, 2025
Metallic Biomaterials for Pharmaceutical and Biomedical Applications
Metals in Medicine Volume 1 Metals for Tissue Engineering and Pharmaceutical Applications, 2025
Utilization of Palladium in Photothermal Therapy of Cancer
Metals in Medicine Volume 2 Metallic Nanoparticles for Biomedical Applications, 2025
Rational Design of Antibacterial Agents for Multidrug-Resistant Infections
Sathish Kumar Konidala, Podila Naresh, Risy Namratha Jamullamudi, Kamma Harsha Sri, Richie Rashmin Bhandare, Afzal Basha Shaik
Computational Methods for Rational Drug Design, 2025
HR-LCMS Metabolite Profiling and in silico Evaluation of the Antidiabetic Activity of Methanolic Leaf Extract of Chrozophora rottleri (Geiseler) A. Juss. Ex Spreng.
Srilakshmi Nallapaty, Narender Malothu, Sathish Kumar Konidala, Anka Rao Areti, Chakravarthi Guntupalli
Indian Journal of Pharmaceutical Education and Research, 2024
Acid Hydrolytic Degradation Profiling of Ezetimibe: Identification, Isolation, and Structural Elucidation of Its Degradants
Arun Kumar Modini, Mahesh Ranga, Sathish Kumar Konidala, Panchumarthy Ravisankar, Kamma Harsha Sri
Separation Science Plus, 2024
Synergistic Amelioration of Letrozole-induced Polycystic Ovary Syndrome in Rats: A Therapeutic Approach with Apple Cider Vinegar and Metformin Combination
Ravi Chandra Sekhara Reddy Danduga, Aarathi Shalom Kurapati, Roohi Anju Shaik, Phani Kumar Kola, Sathish Kumar Konidala, Hema Bharathi Varada
Reproductive Sciences, 2024
Development of Orally Active Anti-Inflammatory Agents: In Vivo and In Silico Analysis of Naphthalene-Chalcone Derivatives Based on 2-Acetyl-6-Methoxy Naphthalene
D Vasudha, A Jagadeesh, Sathish Kumar Konidala, Haya Yasin, Suraj N. Mali, Richie R. Bhandare, Afzal B. Shaik
Chemical Physics Impact, 2024
IN SILICO MOLECULAR DOCKING STUDIES OF COUMARIN-CHALCONE HYBRIDS AGAINST SARS-COV-2 MAIN PROTEASE (6LU7)
, Sathish K. Konidala, Vijay Kotra, Ramu Samineni, Abdul R. Shaik, Lakshmi S. Nissankara Rao, Risy N. Jamullamudi, Phani K. Kola
Indian Drugs, 2024
Design, synthesis, biological and computational screening of novel pyridine-based thiadiazole derivatives as prospective anti-inflammatory agents
Naresh Podila, Naveen Kumar Penddinti, Mithun Rudrapal, Gourav Rakshit, Sathish Kumar Konidala, Veera Shakar Pulusu, Richie R. Bhandare, Afzal B. Shaik
Heliyon, 2024
Simultaneous Quantification of Gemcitabine and Oxaliplatin by RP-HPLC in Bulk and Synthetic Mixture
Letters in Applied Nanobioscience, 2024
Evaluation of in vitro antidiabetic and antioxidant activity of leaf extracts of Ecbolium linneanum kurz.: GC-MS and HR-LCMS-based metabolite profiling and an in silico approach
Srilakshmi Nallapaty, Narender Malothu, Sathish Kumar Konidala, Anka Rao Areti
Journal of Applied Pharmaceutical Science, 2024
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF NOVEL BIS-HETERO CYCLIC DERIVATIVES
, Sathish K. Konidala, Govindarao Kamala, Srinivasan Nagarajan, Durga R. Gunna
Indian Drugs, 2023
Pharmacognostic and Phytochemical Evaluation with Isolation and Anthelmintic Activity of Dypsis lutescens Leaf extracts
Latin American Journal of Pharmacy, 2023
Identification, Isolation, and Structural Characterization of Novel Forced Degradation Products of Darunavir Using Advanced Analytical Techniques Like UPLC–MS, Prep-HPLC, HRMS, NMR, and FT-IR Spectroscopy
Arun Kumar Modini, Mahesh Ranga, Umamaheshwar Puppala, Muralidharan Kaliyapermal, Mahesh Kumar Reddy Geereddy, Ramu Samineni, Parul Grover, Sathish Kumar Konidala
Chromatographia, 2023
Development and Validation of UPLC-MS/MS Method for Simultaneous Determination of Multi-Class Antibiotics, Antivirals and Antifungals in Water
SATHISH KUMAR KONIDALA, SIVA SHANMUGAM S, S. NARAYANAN, R.K. SHANDIL, PAVAN KUMAR PURAM, RAMU SAMINENI, VEERA SHAKAR PULUSU, KAMMA HARSHA SRI
Asian Journal of Chemistry, 2023
Development and Validation of Analytical Method for Estimation of Balofloxacin in Bulk and Pharmaceutical Dosage Form by RP-HPLC
Ramu Samineni, Jithendra Chimakurthy, Sathish Kumar Konidala, Venkateswarao Yamarthy
Research Journal of Pharmacy and Technology, 2022
Novel RP-UPLC Method Development and Validation for Simultaneous Quantification of Emtricitabine, Tenofovir and Efavirenz in Bulk and Tablet Dosage Forms
Sathish Kumar Konidala, Ramu Samineni, Yamarthi Venkateswara Rao, Jithendra Chimakurthy, Chaitanya Sucharitha Kolakaluri, Vishali Korrapati
Research Journal of Pharmacy and Technology, 2022
Multistep synthesis and screening of heterocyclic tetrads containing furan, pyrazoline, thiazole and triazole (or oxadiazole) as antimicrobial and anticancer agents
Richie R Bhandare, Chandrashekar S.Munikrishnappa, G.V. Suresh Kumar, Sathish Kumar Konidala, Dilep Kumar Sigalapalli, Yogesh Vaishnav, Sampath Chinnam, Haya Yasin, Ahmed A. Al-karmalawy, Afzal B. Shaik
Journal of Saudi Chemical Society, 2022
Emerging Role of Biopharmaceutical Classification and Biopharmaceutical Drug Disposition System in Dosage form Development: A Systematic Review
Ramu SAMINENI, Jithendra CHIMAKURTHY, Sathish KONIDALA
Turkish Journal of Pharmaceutical Sciences, 2022
Anti-inflammatory and antioxidant activities of 4-allylpyrocatechol and its derivatives with molecular docking and ADMET investigations
T. Annavarapu, , S. Kamepalli, S.K. Kondala, V. Kotra, S.R. Challa, M. Rudrapal, A.R. Bendale, , , , , , and
Bulletin of the Karaganda University Chemistry Series, 2022
Design, multistep synthesis and in-vitro antimicrobial and antioxidant screening of coumarin clubbed chalcone hybrids through molecular hybridization approach
Sathish Kumar Konidala, Vijay Kotra, Ravi Chandra Sekhara Reddy Danduga, Phani Kumar Kola, Richie R. Bhandare, Afzal B. Shaik
Arabian Journal of Chemistry, 2021
ZnCl2 catalyzed new coumarinyl-chalcones as cytotoxic agents
Konidala Sathish Kumar, Vijay Kotra, Phani Kumar Kola, CH.B. Praveena Devi, Nutakki Anusha, Bollikolla Hari Babu, Syed Farooq Adil, Mohammed Rafi Shaik, Mujeeb Khan, Abdulrahman Al-Warthan, Osamah Alduhaish, M. Mujahid Alam
Saudi Journal of Biological Sciences, 2021
Coumarin-chalcone hybrids targeting insulin receptor: Design, synthesis, anti-diabetic activity, and molecular docking
Sathish Kumar Konidala, Vijay Kotra, Ravi Chandra Sekhara Reddy Danduga, Phani Kumar Kola
Bioorganic Chemistry, 2020
Development and validation of uv spectroscopic method for the determination of ranolazine in bulk and formulation
DVS Roopa Sirisha Doppa, Sathish Kumar Konidala, Sheik Khanabhi
Research Journal of Pharmacy and Technology, 2019
A review on role of telemedicine in disaster management: A pharmacist perspective
Anusha Nutakki, Vijay Kotra, Sathish Kumar Konidala, Nagarjuna Babu Etukuri
Springer Series in Geomechanics and Geoengineering, 2019
Spectrophotometric Determination of Eprosartan Based on Oxidation by Acidic KMnO4 in Bulk and Dosage Form
Sathish Kumar Konidala
Analytical Chemistry Letters, 2017
Recent advances and applications of turbulent flow chromatography
Vijay Kotra, Sathish Kumar Konidala, N. Anusha, R. Nageswara Rao, B. Hari Babu
Asian Journal of Chemistry, 2017
Laser induced breakdown spectroscopy
Sathish Kumar Konidala, Govindarao Kamala, Sravani Koralla
Research Journal of Pharmacy and Technology, 2016
Stability-indicating RP-HPLC method development & validation for simultaneous determination of doxylamine succinate and dextromethorphan hydrobromide in pharmaceutical dosage forms
Der Pharmacia Lettre, 2015
New validated visible spectrophotometric method for the determination of salbutamol sulphate in bulk and dosage form
International Journal of Pharmacy and Technology, 2015
New validated RP-HPLC method for the determination of rizatriptan benzoate in bulk and pharmaceutical dosage form
Indian Drugs, 2014
New validated RP-HPLC method for the determination of Ritonavir in bulk and pharmaceutical dosage form
International Journal of Pharmacy and Pharmaceutical Sciences, 2013
Development and validation of UV spectroscopic method for determination of atazanavir sulphate in bulk and formulation
International Journal of Pharmacy and Pharmaceutical Sciences, 2012
New Validated RP-HPLC method for the Determination of Atazanavir Sulphate in Bulk and Dosage form
Der Pharma Chemica, 2012
Electrochemical sensors and biosensors for the pharmaceutical and environmental analysis
International Journal of Pharmacy and Technology, 2011
Two dimensional gas chromatography
International Journal of Pharmacy and Technology, 2011

RECENT SCHOLAR PUBLICATIONS

Development and validation of an LC–MS/MS method for Lazertinib in rat plasma using SFOD microextraction with pharmacokinetic application
R Guntupalli, P Ravisankar, SK Konidala
Microchemical Journal, 118412 , 2026
2026
A Robust LC‐MS/MS Bioanalytical Strategy for Simultaneous Quantification of Tramadol HCl and Dexketoprofen Trometamol and Its Use in Pharmacokinetic Studies
AS Rao, P Bangaraiah, SK Konidala
Biomedical Chromatography 40 (4), e70398 , 2026
2026
Network Pharmacology and Molecular Docking‐Based in Silico Investigation of Anti‐Atherosclerotic Phytoactives From Annona Reticulata and Ocimum Basilicum
P Gelam, R Muddala, SSN Kaipu, S Boyapati, RR Vadapalli, SK Konidala, ...
ChemistrySelect 11 (11), e06652 , 2026
2026
Validated LC‐MS/MS Method for Quantification and Pharmacokinetic Analysis of Talazoparib and Enzalutamide in Rats
R Guntupalli, P Ravisankar, SK Konidala
Biomedical Chromatography 40 (3), e70381 , 2026
2026
Simultaneous quantification of linezolid and pretomanid in BALB/c mice plasma using a validated LC-MS/MS method: Application to pharmacokinetic and lung distribution studies
S Siva Shanmugam, SK Konidala, S Narayanan, RK Shandil
Acta Chromatographica, 1326.2026. 01448 , 2026
2026
Development of a New Validated RP-HPLC Method for Simultaneous Estimation and Stability Study of Tegafur, Gimeracil and Oteracil in Combined Dosage Form.
R Panchumarthy, SK Konidala, KH Sri, CS Kolakaluri, ...
Indian Journal of Pharmaceutical Education & Research 60 , 2026
2026
Quantification of Belzutifan in Biological Samples: LC–MS/MS Method Validation and Pharmacokinetic Study in Rats
KH Sri, P Ravisankar, SK Konidala, SB Puttagunta
Biomedical Chromatography 39 (9), e70168 , 2025
2025
Citations: 1
Rhizophora apiculata extracts improved memory function through inhibition of acetylcholinesterase and oxidative stress in scopolamine-induced memory deficits in rats
A Mande, M Narender, C Guntupalli, K Ramakrishna, SK Konidala
Avicenna Journal of Phytomedicine , 2025
2025
Novel quinoline-4-thiazolidinone derivatives as anticancer agents targeting the biological macromolecular protein-EGFR tyrosine kinase with dual anticancer and antioxidant …
SK Konidala, GR Kamala, RR Bhandare, AB Shaik
Journal of Molecular Structure, 143607 , 2025
2025
Citations: 3
Metals in Medicine: Volume 1: Metals for Tissue Engineering and Pharmaceutical Applications
S Sundram, R Malviya, GSNK Rao
CRC Press , 2025
2025
Utilization of Palladium in Photothermal Therapy of Cancer
SK Konidala, BS Padya, GSNK Rao, RR Budha
Metals in Medicine, 371-392 , 2025
2025
Metallic Biomaterials for Pharmaceutical and Biomedical Applications
S Chaudhary, RR Budha, GSNK Rao, SK Konidala
Metals in Medicine, 41-57 , 2025
2025
Citations: 1
IN VIVO AND IN SILICO ANTI-ATHEROSCLEROTIC ACTIVITY OF ETHANOLIC LEAVES EXTRACT OF OCIMUM BASILICUM AND ANNONA RETICULATE.
P Gelam, RR Vadapalli, SK Konidala, R Muddala, B Bonthagarala, ...
Indian Drugs 62 (2) , 2025
2025
Citations: 1
Rational Design of Antibacterial Agents for Multidrug‐Resistant Infections
SK Konidala, P Naresh, RN Jamullamudi, KH Sri, RR Bhandare, AB Shaik
Computational Methods for Rational Drug Design, 403-421 , 2025
2025
Citations: 1
Simultaneous Quantification of Multi-Class Antimicrobials in Chicken Kidney and Liver by New Validated UPLC-MS/MS Method
SK Konidala, S Narayanan, S Rk
Hacettepe University Journal of the Faculty of Pharmacy 45 (1), 30-42 , 2025
2025
Quantification of Vactosertib an Inhibitor of TGFBR1 by LC–MS/MS in Rat Plasma and Its Pharmacokinetic Profiling
RK Boggavarapu, J Chimakurthy, SK Konidala
Biomedical Chromatography 39 (1), e6057 , 2025
2025
Citations: 1
Computational methods for rational drug design
M Rudrapal
John Wiley & Sons , 2024
2024
Citations: 13
HR-LCMS Metabolite Profiling and in silico Evaluation of the Antidiabetic Activity of Methanolic Leaf Extract of Chrozophora rottleri (Geiseler) A. Juss. Ex Spreng
S Nallapaty, N Malothu, SK Konidala, AR Areti, C Guntupalli
Indian Journal of Pharmaceutical Education and Research 58 (4), 1277-1286 , 2024
2024
Citations: 6
Acid Hydrolytic Degradation Profiling of Ezetimibe: Identification, Isolation, and Structural Elucidation of Its Degradants
AK Modini, M Ranga, SK Konidala, P Ravisankar, KH Sri
Separation Science Plus 7 (10), e202400135 , 2024
2024
Citations: 1
Synergistic amelioration of letrozole-induced polycystic ovary syndrome in rats: a therapeutic approach with apple cider vinegar and metformin combination
RCSR Danduga, AS Kurapati, RA Shaik, PK Kola, SK Konidala, ...
Reproductive Sciences 31 (9), 2861-2876 , 2024
2024
Citations: 1

MOST CITED SCHOLAR PUBLICATIONS

Emerging role of biopharmaceutical classification and biopharmaceutical drug disposition system in dosage form development: A systematic review
R Samineni, J Chimakurthy, S Konidala
Turkish journal of pharmaceutical sciences 19 (6), 706 , 2022
2022
Citations: 146
Multistep synthesis and screening of heterocyclic tetrads containing furan, pyrazoline, thiazole and triazole (or oxadiazole) as antimicrobial and anticancer agents
RR Bhandare, CS Munikrishnappa, GVS Kumar, SK Konidala, ...
Journal of Saudi Chemical Society 26 (3), 101447 , 2022
2022
Citations: 60
Design, multistep synthesis and in-vitro antimicrobial and antioxidant screening of coumarin clubbed chalcone hybrids through molecular hybridization approach
SK Konidala, V Kotra, RCSR Danduga, PK Kola, RR Bhandare, AB Shaik
Arabian Journal of Chemistry 14 (6), 103154 , 2021
2021
Citations: 53
Coumarin-chalcone hybrids targeting insulin receptor: Design, synthesis, anti-diabetic activity, and molecular docking
SK Konidala, V Kotra, RCSR Danduga, PK Kola
Bioorganic chemistry 104, 104207 , 2020
2020
Citations: 51
Design, synthesis, biological and computational screening of novel pyridine-based thiadiazole derivatives as prospective anti-inflammatory agents
N Podila, NK Penddinti, M Rudrapal, G Rakshit, SK Konidala, VS Pulusu, ...
Heliyon 10 (8) , 2024
2024
Citations: 32
New Validated RP-HPLC method for the Determination of Atazanavir Sulphate in Bulk and Dosage form
SK Konidala, K Sujana, AP Rani
Der Pharma Chemica 4 (3), 1305-1310 , 2012
2012
Citations: 23
Identification, isolation, and structural characterization of novel forced degradation products of Darunavir using advanced analytical techniques like UPLC–MS, prep-HPLC, HRMS …
AK Modini, M Ranga, U Puppala, M Kaliyapermal, MKR Geereddy, ...
Chromatographia 86 (1), 63-78 , 2023
2023
Citations: 20
Novel RP-UPLC method development and validation for simultaneous quantification of emtricitabine, tenofovir and efavirenz in bulk and tablet dosage forms
SK Konidala, R Samineni, YV Rao, J Chimakurthy, CS Kolakaluri, ...
Research Journal of Pharmacy and Technology 15 (7), 3141-3146 , 2022
2022
Citations: 17
Development of orally active anti-inflammatory agents: In vivo and in silico analysis of naphthalene-chalcone derivatives based on 2-acetyl-6-methoxy naphthalene
D Vasudha, A Jagadeesh, SK Konidala, H Yasin, SN Mali, RR Bhandare, ...
Chemical Physics Impact 8, 100472 , 2024
2024
Citations: 16
ZnCl2 catalyzed new coumarinyl-chalcones as cytotoxic agents
KS Kumar, V Kotra, PK Kola, CHBP Devi, N Anusha, BH Babu, SF Adil, ...
Saudi Journal of Biological Sciences 28 (1), 386-394 , 2021
2021
Citations: 16
Development and validation of UV spectroscopic method for the determination of ranolazine in bulk and formulation
DVSRS Doppa, SK Konidala, S Khanabhi
Research Journal of pharmacy and Technology 12 (10), 5007-5010 , 2019
2019
Citations: 14
Computational methods for rational drug design
M Rudrapal
John Wiley & Sons , 2024
2024
Citations: 13
Laser Induced Breakdown Spectroscopy
SK Sathish Kumar Konidala, Govindarao Kamala
Research Journal of Pharmacy and Technology 9 (1), 91-100 , 2016
2016
Citations: 13
Development and validation of UV spectroscopic method for determination of atazanavir sulphate in bulk and formulation
SK Konidala, K Sujana
Int. J. Pharm. Pharm. Sci 4 (3) , 2012
2012
Citations: 13
Development and validation of RP-HPLC method for simultaneous estimation of Paracetamol and Flupirtine Maleate
SK Konidala, A Penumala, VK Mugada, GR Kamala
Asian Journal of Pharmaceutical Analysis 5 (2), 105-11 , 2015
2015
Citations: 12
Stability indicating RP-HPLC method for simultaneous estimation of ramipril and amlodipine besylate in pharmaceutical dosage form
S Koralla, SK Konidala, KG Rao, SM Begum
Asian Journal of Pharmaceutical Research 6 (4), 242-249 , 2016
2016
Citations: 10
DEVELOPMENT AND VALIDATION OF NEW SPECTROSCOPIC METHOD FOR THE ESTIMATION OF VALGANCYCLOVIR HCL IN BULK AND PHARMACEUTIC DOSAGE FORM
OTDDDRS Sathish Kumar Konidala , N Yamini Sai Silpa, K Samrajyam
World Journal of Pharmaceutical Research 3 (3), 4773-4782 , 2014
2014
Citations: 10
A simple and validated RP-HPLC method for the simultaneous determination of vildagliptin and metformin in bulk and pharmaceutical dosage forms
SK Konidala, P Hemanth
Int J Curr Pharm Res 6 (2), 31-35 , 2014
2014
Citations: 10
Evaluation of in vitro antidiabetic and antioxidant activity of leaf extracts of Ecbolium linneanum kurz.: GC-MS and HR-LCMS based metabolite profiling and an in silico approach
S Nallapaty, N Malothu, SK Konidala, AR Areti
Journal of Applied Pharmaceutical Science 14 (1), 247-260 , 2024
2024
Citations: 8
Development and validation of analytical method for estimation of balofloxacin in bulk and pharmaceutical dosage form by RP-HPLC
R Samineni, J Chimakurthy, SK Konidala, V Yamarthy
Research Journal of Pharmacy and Technology 15 (7), 2992-2996 , 2022
2022
Citations: 8

Dr Sathish Kumar Konidala

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