Flexible Laser-Induced Graphene Microelectrochemical Sensor on Sustainable Cellulosic Paper Substrate for Sensitive Detection of Uric Acid and Tyrosine in Sweat Ali Ghavipanjeh, Sadegh Sadeghzadeh, Seyed Morteza Naghib, Kheibar Dashtian Langmuir, 2026 Graphene-based flexible electrochemical sweat sensors have garnered significant attention in both medical and athletic application fields due to their ability to provide critical insights into the body’s physiological condition. Herein, we employed a green laser-induced graphene (LIG) technique using a CO2 laser on a cellulose-based paper substrate to fabricate a microelectrochemical sensor capable of detecting tyrosine and uric acid in sweat samples. Electrochemical analysis determined the heterogeneous electron transfer (HET) rate constant (k0) to be 4 × 10–3 cm/s and confirmed that the LIG sensor maintained stability across various pH levels. For tyrosine detection, the sensor exhibited a broad linear detection range from 30 to 1000 μM, with a limit of detection (LOD) of 12.4 μM and a sensitivity of approximately 9 mAM–1. For uric acid, the working range extended from 5 to 100 μM, with an LOD of 2.9 μM and a sensitivity of around 1 mAM–1. These results demonstrate performance comparable to or surpassing existing flexible graphene-based sensors. Selectivity tests confirmed the sensor’s ability to distinguish tyrosine and uric acid in the presence of common sweat interferents such as glucose, lactic acid, and ascorbic acid. Additionally, the mechanism of LIG formation on the cellulosic substrate was validated using molecular dynamics simulations with the ReaxFF force field, showing strong agreement with experimental data. The developed microelectrochemical sensor exhibited reliable and effective performance, underscoring its potential for sustainable, noninvasive health monitoring, and clinical diagnostics.
Thermal shock resistance of different configurations of C₃N/BN hybrid nanostructures Tala Jalalian, Sadegh Sadeghzadeh, Hosein Banna Motejadded Emrooz Molecular Simulation, 2026 This study investigates the thermal response of BN, C₃N, and their hybrid structures (BN/C₃N/BN and C₃N/BN/C₃N) under thermal shock conditions using molecular dynamics simulations with the Tersoff potential. The simulations employ periodic boundary conditions along all axes, with a thermal shock of 4000 K applied to one side, while the opposite side is maintained at a steady state. Using Fourier's law, the thermal conductivity of C₃N and BN is determined to be 846 and 527 W/(mK), respectively. The thermal shock propagation time within the system differs across materials: 6.35 ps for BN, 6.3 ps for C₃N, 6.5 ps for BN/C₃N/BN, and 6.8 ps for C₃N/BN/C₃N. The hybrid structures exhibit a reduction in temperature intensity but show increased temperature fluctuations and stress, particularly at the interfaces. Notable differences in interfacial thermal resistance (ITR) between the left and right interfaces arise due to higher energy dissipation at the left interface. These results underscore the crucial role of atomic arrangements and bonding in thermal performance, providing valuable insights for designing materials with enhanced thermal efficiency. Such materials hold promise for applications in thermal transistors, logic circuits, and diodes, advancing thermal management and energy-efficient technologies.
Thermal shock resistance of various two-dimensional materials: a comparative analysis Ali Ghavipanjeh, Sadegh Sadeghzadeh, Nader Malih Rsc Advances, 2026 Understanding the ultrafast thermomechanical response of two-dimensional (2D) materials is crucial for their integration into next-generation nanoelectronic and thermal management technologies.
Alkyd coated laser induced graphene patches for corrosion resistance of metal substrates Mir Mehdi Hashemi, Farzane Hahseminia, Sadegh Sadeghzadeh Scientific Reports, 2025 Corrosion can severely degrade surfaces and materials, impacting both functionality and safety. Laser-induced graphene (LIG) offers substantial corrosion resistance, making it an ideal material for protecting metals, such as carbon steel. This study developed adhesive, corrosion-resistant LIG patches on polyimide (PI) layers, enhanced with an alkyd resin coating, and applied to pretreated aluminum surfaces. LIG was synthesized using laser powers of 6, 8, 10, and 12 W, followed by alkyd coating for improved performance. Results of EDS, SEM, TGA, XRD, Raman spectroscopy, and surface-wetting properties are studied. SEM and XRD analyses revealed that a lower laser power (6 W) produced uniform, crystalline LIG, whereas a higher power (12 W) caused defects and porosity. Corrosion tests in an alkaline environment showed that the A-LIG6@PI patch had the best structural integrity, with minimal pitting after 96 h, outperforming other samples. The electrochemical analysis demonstrated a corrosion inhibition efficiency of 98.36% for A-LIG6@PI, with a corrosion current density of 0.11 µA/cm² and polarization resistance (Rp) of 8.51 × 10⁶ Ω·cm². Contact angle measurements confirmed enhanced hydrophobicity, with A-LIG6@PI showing an 88° angle compared to 58° for bare LIG. The electrochemical analysis demonstrated a corrosion inhibition efficiency of 98.36% for A-LIG6@PI in 3.5 wt% NaCl solution, outperforming higher-power LIG samples (e.g., 66.81% for uncoated LIG12@PI), while maintaining structural integrity on aluminum substrates after 96 h. These results highlight the potential of using lower laser power to create durable, corrosion-resistant graphene-based coatings suitable for flexible electronics, automotive components, marine structures, oil and gas pipelines, and protective applications.
Geometric effects on nanopore creation in graphene and on the impact-withstanding efficiency of graphene nanosheets Mechanics of Advanced Composite Structures, 2018
Sensitivity analysis of fiber-reinforced lamina micro-electro-mechanical switches with nonlinear vibration using a higher order hamiltonian approach Mechanics of Advanced Composite Structures, 2018
TiO2@ Ag-Nanowires Bent onto LIG Electrodes: Fabrication and Characterization of Wearable UV Photodetectors MM Hashemi, A Heydariyan, S Sadeghzadeh, S Hussain, RK Manavalan Sensors and Actuators A: Physical, 117641 , 2026 2026
Thermal shock resistance of different configurations of C₃N/BN hybrid nanostructures T Jalalian, S Sadeghzadeh, HB Motejadded Emrooz Molecular Simulation, 1-16 , 2026 2026
Wearable Multifunctional Microfluidic Pressure Sensor based on Activated Laser-induced Biochar Nanofluid for Human Health Monitoring Applications MM Hashemi, F Hasheminia, A Heydariyan, S Sadeghzadeh Biosensors and Bioelectronics, 118462 , 2026 2026
Cellulose-Based Laser-Induced Graphene: Progress and Prospects A Ghavipanjeh, S Sadeghzadeh Polymer Reviews, 1-64 , 2026 2026 Citations: 4
Synergistic Role of Silica Nanoparticles and SDS Surfactants in Oil-Water Interfacial Detachment: A Molecular Dynamics Study S Sadeghzadeh Journal of Nano Simulation 2 (1), 21-35 , 2026 2026
Thermal shock resistance of various two-dimensional materials: a comparative analysis A Ghavipanjeh, S Sadeghzadeh, N Malih RSC advances 16 (18), 16088-16104 , 2026 2026
laser-induced graphene for high-performance pressure sensors F Sistani, S Sadeghzadeh Journal of Materials Science, 1-92 , 2025 2025 Citations: 1
Flexible Laser-Induced Graphene Microelectrochemical Sensor on Sustainable Cellulosic Paper Substrate for Sensitive Detection of Uric Acid and Tyrosine in Sweat A Ghavipanjeh, S Sadeghzadeh, SM Naghib, K Dashtian Langmuir , 2025 2025 Citations: 8
Efficient hybrid machine learning model for inverse design of porous boron nitride with high thermal conductivity S Khajeh, A Mayelifartash, A Ranjbar, MA Abdol, S Sadeghzadeh, ... Solid State Communications 404, 116051 , 2025 2025 Citations: 2
Alkyd coated laser induced graphene patches for corrosion resistance of metal substrates MM Hashemi, F Hahseminia, S Sadeghzadeh Scientific Reports 15 (1), 31453 , 2025 2025 Citations: 2
Tailoring the nanoporous graphene for energy-efficient ethylene separation from ethane M Attari, J Mahmoudi, S Sadeghzadeh, MA Abdol Molecular Simulation 51 (11), 780-790 , 2025 2025 Citations: 1
Influence of water on CO2/H2S geo-sequestration in shale nanopores: A GCMC-MD simulation study M Moradi, J Mahmoudi, D Ajloo, S Sadeghzadeh Computational Materials Science 255, 113871 , 2025 2025 Citations: 3
Highly sensitive strain sensors with minimal hysteresis using laser-induced graphene S Sadeghzadeh Applied Physics A 131 (4), 293 , 2025 2025 Citations: 6
Exceptional potential of laser-induced graphene for self-healing applications F Hasheminia, M Rasoulzadeh, A Ghavipanjeh, S Sadeghzadeh Computational Materials Science 251, 113742 , 2025 2025 Citations: 1
Investigating the impact of two-dimensional BC 3 membrane geometry on ethane/ethylene separation using molecular dynamics M Attari, J Mahmoudi, S Sadeghzadeh Applied Physics A 130 (12), 913 , 2024 2024 Citations: 3
Laser-induced graphene in energy storage-batteries F Hasheminia, S Sadeghzadeh Nano-Structures & Nano-Objects 40, 101347 , 2024 2024 Citations: 15
Silver-decorated laser-induced graphene for a linear, sensitive, and almost hysteresis-free piezoresistive strain sensor F Abedheydari, S Sadeghzadeh, M Saadatbakhsh, A Heydariyan, ... Scientific Reports 14 (1), 28715 , 2024 2024 Citations: 16
Tailoring the thermal transport properties of cellulose and lignin laser-induced graphene A Ghavipanjeh, S Sadeghzadeh Computational Materials Science 244, 113240 , 2024 2024 Citations: 10
Mechanical properties of C3N-BN hybrid nanosheets: Insights from molecular dynamics simulations S Sadeghzadeh, L Badrinezhad, KE Eshkalak Diamond and Related Materials 147, 111323 , 2024 2024 Citations: 8
Improving the thermal shock response of aluminum by graphene composition S Sadeghzadeh, M Hamzavi, F Hasheminia, H Khashei Materials Today Communications 40, 110093 , 2024 2024 Citations: 2
MOST CITED SCHOLAR PUBLICATIONS
Numerical investigation on PCM encapsulation shape used in the passive-active battery thermal management M Safdari, R Ahmadi, S Sadeghzadeh Energy 193, 116840 , 2020 2020 Citations: 268
The role of surface chemistry on CO 2 adsorption in biomass-derived porous carbons by experimental results and molecular dynamics simulations MS Khosrowshahi, MA Abdol, H Mashhadimoslem, E Khakpour, ... Scientific Reports 12 (1), 8917 , 2022 2022 Citations: 147
An overview of atmospheric water harvesting methods, the inevitable path of the future in water supply Z Ahrestani, S Sadeghzadeh, HBM Emrooz RSC advances 13 (15), 10273-10307 , 2023 2023 Citations: 104
Mechanical properties of defective hybrid graphene-boron nitride nanosheets: A molecular dynamics study KE Eshkalak, S Sadeghzadeh, M Jalaly Computational Materials Science 149, 170-181 , 2018 2018 Citations: 96
Molecular dynamics simulations of phase change materials for thermal energy storage: a review H Tafrishi, S Sadeghzadeh, R Ahmadi RSC advances 12 (23), 14776-14807 , 2022 2022 Citations: 83
Enhanced atmospheric water harvesting efficiency through green-synthesized MOF-801: a comparative study with solvothermal synthesis M Aghajani Hashjin, S Zarshad, HB Motejadded Emrooz, S Sadeghzadeh Scientific Reports 13 (1), 16983 , 2023 2023 Citations: 73
Numerical and experimental investigation on electric vehicles battery thermal management under New European Driving Cycle M Safdari, R Ahmadi, S Sadeghzadeh Applied Energy 315, 119026 , 2022 2022 Citations: 69
Investigation of tetracosane thermal transport in presence of graphene and carbon nanotube fillers––A molecular dynamics study H Tafrishi, S Sadeghzadeh, R Ahmadi, F Molaei, F Yousefi, H Hassanloo Journal of Energy Storage 29, 101321 , 2020 2020 Citations: 63
A comparative study on the mechanical, physical and morphological properties of cement-micro/nanoFe 3 O 4 composite SI Ghazanlou, M Jalaly, S Sadeghzadeh, AH Korayem Scientific Reports 10 (1), 2859 , 2020 2020 Citations: 56
Simulation and experimental evaluation of laser-induced graphene on the cellulose and lignin substrates A Ghavipanjeh, S Sadeghzadeh Scientific Reports 14 (1), 4475 , 2024 2024 Citations: 52
Computational finite element methods in nanotechnology SM Musa CRC Press , 2012 2012 Citations: 48
A new multiscale methodology for modeling of single and multi-body solid structures MH Korayem, S Sadeghzadeh, V Rahneshin Computational Materials Science 63, 1-11 , 2012 2012 Citations: 46
Effect of Nb on the structural, optical and photocatalytic properties of Al-doped ZnO thin films fabricated by the sol-gel method H Jafari, S Sadeghzadeh, M Rabbani, R Rahimi Ceramics International 44 (16), 20170-20177 , 2018 2018 Citations: 44
The mechanical design of hybrid graphene/boron nitride nanotransistors: geometry and interface effects KE Eshkalak, S Sadeghzadeh, M Jalaly Solid State Communications 270, 82-86 , 2018 2018 Citations: 44
Effects of vacancies and divacancies on the failure of C3N nanosheets S Sadeghzadeh Diamond and Related Materials 89, 257-265 , 2018 2018 Citations: 41
Interfacial Thermal Resistance Mechanism for the Polyaniline (C 3 N)–Graphene Heterostructure K Einalipour Eshkalak, S Sadeghzadeh, F Molaei The Journal of Physical Chemistry C 124 (26), 14316-14326 , 2020 2020 Citations: 40
Application of higher order Hamiltonian approach to the nonlinear vibration of micro electro mechanical systems S Sadeghzadeh, A Kabiri Latin American Journal of Solids and Structures 13, 478-497 , 2016 2016 Citations: 36
Thermal resistance analysis of hybrid graphene-boron nitride nanosheets: the effect of geometry, temperature, size, strain and structural defects KE Eshkalak, S Sadeghzadeh, M Jalaly Computational Materials Science 174, 109484 , 2020 2020 Citations: 35
Studying the effects of longitudinal and transverse defects on the failure of hybrid graphene-boron nitride sheets: A molecular dynamics simulation KE Eshkalak, S Sadeghzadeh, M Jalaly Physica E: Low-dimensional Systems and Nanostructures 104, 71-81 , 2018 2018 Citations: 35
Molecular dynamics simulations of methane adsorption and displacement from graphenylene shale reservoir nanochannels M Hajianzadeh, J Mahmoudi, S Sadeghzadeh Scientific Reports 13 (1), 15765 , 2023 2023 Citations: 34
