Dr. Sachin Kamlakar Jagdale

Scopus Publications

A review exploring the translational perspective of artificial intelligence in drug discovery and formulation development
Babita Agarwal, Saurabh Gaware, Namdev More, Rushikesh Shinde, Hagalavadi Nanjappa Shivakumar, Sachin Jagdale
Annales Pharmaceutiques Francaises, 2026
Brinzolamide microsponge-loaded in situ gel for sustained ocular delivery: design, characterization and in vivo evaluation
Babita Agarwal, Shivshankar Chandapure, Aditya Kakad, Namdev More, Prabhakar Panzade, Pavan Rathi, Pravin Patil, Sachin Jagdale
Naunyn Schmiedeberg S Archives of Pharmacology, 2026
Measurement, correlation and prediction of etoricoxib solubility in aqueous mixtures of 1-propanol, 2-propanol, formamide, N-methyl-2-pyrrolidone and ethylene glycol using computational models
Pavan Rathi, Mayura Kale, Sachin Jagdale, Abolghasem Jouyban
Journal of Molecular Liquids, 2025
Thermodynamic modeling and solubility behavior of etoricoxib in different mono-solvents at different temperatures
Pavan Rathi, Mayura Kale, Sachin Jagdale, Abolghasem Jouyban
Journal of Molecular Liquids, 2025
Solubility, thermodynamic properties and predictive modeling of glimepiride in various solvents
Sachin Jagdale, Babita Agarwal, Simran Karekar, Pavan Rathi, Vahid Jouyban-Gharamaleki, Dmitriy M. Makarov, Abolghasem Jouyban
Journal of Molecular Liquids, 2025
WHITE ANALYTICAL CHEMISTRY (WAC) - A SUSTAINABLE AND EFFECTIVE APPROACH TO MODERN ANALYTICAL SCIENCE
Pharma Times, 2025
Nepafenac Loaded Emulgel for Controlled Ocular Delivery: in vitro and ex vivo Characterization
Babita Agarwal, Sachin Jagdale, Tejaswini Kanakdande, Rushikesh Shinde
Indian Journal of Pharmaceutical Education and Research, 2025
Development and Validation of Stability Indicating RP-HPLC Method for the Estimation of Glycopyrrolate and Neostigmine in Bulk and Injection
Babita Agarwal, Sachin Jagdale, Prasad Kadam, Pramod Sakpal, Santaji Nalawade, Shivraj Maske, Pooja Dale
Journal of Chromatographic Science, 2024
A stability indicating RP-HPLC method is suggested for determination of Glycopyrrolate-Neostigmine (GLY/NEO) in bulk drugs and injection formulation. GLY/NEO were eluted from a Chromolith High Resolution RP-18e (100 mm×4.6 mm) with buffer solution (pH 3.0) as mobile phase A and a mixture of HPLC grade acetonitrile and water mixture (90:10) as mobile phase B. The gradient was optimized with a flowrate of 0.5 mL/min and wavelength of 222 nm. A complete analytical method validation was effectively carried out as per ICH Q2 (R1) guidelines. Recovery studies were performed at 50–150% level of working concentrations, and results were in the range of 99–101%. The linearity was detected in the range of LOQ to 200% of the specification limits i.e., 0.5% each for NEO and GLY, 0.01% for NEO Impurity B and 1.0% for rest of the impurities with respect to the test concentration of the respective components. For stability study, various stress conditions such as acid, base, oxidation and thermal as per ICH guidelines were studied. The high recovery and low relative standard deviation confirm the suitability of proposed method that can be employed for the routine analysis in bulk and pharmaceutical formulation.
Chitosan as excellent bio-macromolecule with myriad of anti-activities in biomedical applications – A review
Sachin Jagdale, Babita Agarwal, Abhishek Dixit, Saurabh Gaware
International Journal of Biological Macromolecules, 2024
The aim of the study is to explore the myriad of anti-activities of chitosan - deacylated derivative of chitin in biomedical applications. Chitosan consists of reactive residual amino groups, which can be modified chemically to obtain wide range of derivatives. These derivatives exhibit the controlled physicochemical characteristics, which in turn improve its functional properties. Such derivatives find numerous applications in the field of biomedical science, agriculture, tissue engineering, bone regeneration and environmental science. This study presents a comprehensive overview of the multifarious anti-activities of chitosan and its derivatives in the field of biomedical science including anti-microbial, antioxidant, anti-tumor, anti-HIV, anti-fungal, anti- inflammatory, anti-Alzheimer's, anti-hypertensive and anti-diabetic activity. It briefly details these anti-activities with respect to its mode of action, pharmacological effects and potential applications. It also presents the overview of current research exploring novel derivatives of chitosan and its anti- activities in the recent past. Finally, the review projects the prospective potential of chitosan and its derivatives and expects to encourage the readers to develop new drug delivery systems based on such chitosan derivatives and explore its applications in biomedical science for benefit of mankind.
Solid–Liquid Equilibrium Study of Itraconazole in Diethylene Glycol: Water Mixtures at 298.15 K Using Extended Hildebrand Solubility Approach
Sachin K. Jagdale, Rajesh B. Nawale
Chemistry Africa, 2024
Exploring Potential of Nano-formulations in the Treatment of Alzheimer’s Disease through Nasal Route
Avinash Tekade, Prasad Kadam, Sachin Jagdale, Samiksha Surwade, Anil Gaikwad, Parth Pawar, Rushikesh Shinde
Current Alzheimer Research, 2024
Forced Degradation Study of Sofosbuvir: Identification of Degradation Products by LC-ESI-MS
Babita Agarwal, Sachin Jagdale, Santosh Gandhi
Indian Journal of Pharmaceutical Education and Research, 2022
Experimental measurement–correlation of solubility and dissolution thermodynamics study of itraconazole in pure monosolvents at various temperatures
Sachin K. Jagdale, Rajesh B. Nawale
Drug Development and Industrial Pharmacy, 2021
Estimation and Correlation of Solubility of Practically Insoluble Drug Itraconazole in 1,4-Butanediol + Water Mixtures Using Extended Hildebrand Solubility Approach
Sachin K. Jagdale, Rajesh B. Nawale
Journal of Pharmaceutical Innovation, 2020
Bird's eye view on aquasome: Formulation and application
Sachin Jagdale, Simran Karekar
Journal of Drug Delivery Science and Technology, 2020
Extended hildebrand solubility approach: Prediction and correlation of the solubility of itraconazole in triacetin: Water mixtures at 298.15°k
Sachin JAGDALE, Rajesh B NAWALE
Turkish Journal of Pharmaceutical Sciences, 2020
Solubilization and determination of solution thermodynamic properties of itraconazole in different solvents at different temperatures
Sachin K. Jagdale, Rajesh B. Nawale
Drug Development and Industrial Pharmacy, 2019
Enhancement of dissolution of fenofibrate using complexation with hydroxy propyl β-cyclodextrin
Sachin K. JAGDALE, Mohammad H. DEHGHAN, Nilesh S. PAUL
Turkish Journal of Pharmaceutical Sciences, 2019
Development, characterization and optimization of mucoadhesive tablet for buccal delivery of domperidone
Jagdale Sachin, Panbude Aishwarya, Navasare Priya
Drug Delivery Letters, 2019

Dr. Sachin Kamlakar Jagdale

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Scopus Publications