Health-related quality of life in asthma measured by the World Health Organization brief questionnaire (WHO-BREF) and the effect of concomitant allergic rhinitis—A population-based study Obianuju B. Ozoh, Sunday A. Aderibigbe, Adaeze C. Ayuk, Sandra K. Dede, Eruke Egbagbe, et al. Clinical Respiratory Journal, 2025 BACKGROUND AND OBJECTIVE The impact of allergic rhinitis (AR), a common comorbidity in asthma, on global quality of life (QoL) using generic QoL questionnaires has not been extensively evaluated. METHODS This was a cross-sectional population-based study among adults ≥18 years old. Generic QoL was measured using the World Health Organization (WHO) questionnaire (WHOQOL-BREF), and asthma control was assessed using the Asthma Control Test. Participants were categorized into four groups: Group 1 (No asthma, no AR), Group 2 (Asthma only), Group 3 (AR only) and Group 4 (Concomitant asthma and AR). The student t-test or the ANOVA was used for comparison between groups and based on the level of asthma control. Linear regression was used to assess the association between the level of asthma control and QoL scores, adjusted for age and sex. A p-value of less than 0.05 was considered significant for all associations. RESULTS There were 9115 participants; 906 (9.9%) had asthma, and 1998 (21.9%) had AR. The lowest QoL scores were in the environment domain. Mean QoL scores were significantly lower in asthma compared to 'no asthma' and in AR compared to 'no AR'. Either asthma or rhinitis (Group 2 or 3) had significantly lower scores compared to no disease (Group 1) only in the environment domain, but the concomitant disease (Group 4) had lower scores across all categories and domains. Scores were significantly lower for uncontrolled asthma compared to controlled asthma and for 'concomitant asthma and AR' compared to 'asthma only'. Increasing age and uncontrolled asthma predicted worse health-related quality of life (HRQoL) consistently. CONCLUSION Although asthma and AR negatively impact HRQoL independently, concomitant asthma and AR are worse. Uncontrolled asthma underpins poor QoL in asthma because QoL is not impaired in controlled disease. This underscores the need for recognition and treatment of AR in asthma and reinforces the benefits of achieving asthma control as a priority in asthma treatment.
A mixed method assessment of the fertility preferences of clients using antiretroviral therapy in Ilorin, Nigeria-A descriptive cross-sectional survey Adedayo Ayodele Aderibigbe, Sunday Adedeji Aderibigbe, Tanimola Makanjuola Akande, Dooshima Belabo, Joy Abiodun, et al. Nigerian Postgraduate Medical Journal, 2024 Introduction: The burden of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome in Nigeria remains one of the highest in the world, with the country having the highest number of people living with the infection in the West African subregion. Recent estimates put the HIV prevalence rate in Nigeria at 1.9%. In the early years of the HIV epidemic, attention on the reproductive preferences of people living with HIV was not really considered because of the high risk of mortality and few options to reduce mother-to-child transmission. Methodology: A descriptive cross-sectional study was carried out in November 2018 using quantitative and qualitative methods. A total of 400 participants were recruited for the quantitative part of the study and 10 respondents for each of the focus group discussion (FGD) sessions. Data were collected using an interviewer-administered questionnaire and a FGD guide. Frequencies and percentages were determined using descriptive analysis. Univariate analysis was used to explore the association between the outcome variables and the independent variables. The independent variables which showed a significant association in the univariate analysis were further subjected to multivariate analysis. Results: The desire to have children since their HIV diagnosis had been mooted by 255 (63.8%) respondents in the past and 64.5% of the respondents admitted to wanting to have children at some point in the future. More than half of the respondents (61%) currently wanted more children while a significant proportion of the respondents who wanted children (68.4%) wanted more than one child. Conclusion: The study observed that the desire to have children had largely not been affected by the HIV infection as respondents still had a fairly strong desire to continue to have more children in spite of the risks of transmission involved. The study recommended that government and HIV policymakers need to ensure that HIV prevention messages and programmes adopt cultural and socio-economic considerations when designing and planning HIV prevention programmes.
Predictors of Male Involvement in Post-Natal Care Services of their Partners in a Metropolitan City in North-Central Nigeria Aderibigbe Sa Texila International Journal of Public Health, 2020 Background: Men’s behaviour influences the reproductive health of both men and women as well as the health of their children. Yet, men are often unable to make informed decision because they have not been involved in Maternal health services and education. Objective: This study assessed male involvement in Post-Natal healthcare services of their partners and its predictors in Ilorin metropolis, Nigeria. Methods: Multistage sampling technique was used to recruit 350 married adult males whose wives had given birth at least once in the last three years. Descriptive cross-sectional study design was employed. Pretested interview administered semi-structured questionnaires were used for the study. Data was analyzed using SPSS version 21.0 software. A p-value of less than 0.05 was considered as statistically significant. Results: Two-thirds of the respondents (66.6%) had good knowledge of Post-Natal healthcare while a little more than half of the respondents (56.3%) were graded as having high overall involvement in the Post-Natal healthcare of their wives. The predictors of male involvement in postnatal care include the employment status (p=0.01) and educational status (p=0.028) of respondents. Conclusion: Male involvement in postnatal care in Ilorin is fair though it could be better. Being unemployed and not being educated are predictors of male involvement in post-natal care services in Ilorin. There should be increased public enlightenment on the vital roles of men in Post-Natal healthcare services to encourage male involvement, effective service utilization and continuation.
Knowledge of rotavirus gastroenteritis and its current preventive strategies in children, among healthcare providers in Ilorin, North-Central Nigeria MohammedB Abdulkadir, SundayAdedeji Aderibigbe, RasheedahM Ibraheem, Abayomi Fadeyi Nigerian Journal of Basic and Clinical Sciences, 2020 Context: Rotavirus is a leading cause of severe gastroenteritis in children aged less than 5 years. Healthcare providers are responsible for implementing strategies for control of rotavirus gastroenteritis. Aims: To determine knowledge of healthcare providers regarding rotavirus gastroenteritis, its burden, management, and prevention. Materials and Methods: The study was a crosssectional descriptive survey of healthcare providers working in facilities caring for children. A selfadministered questionnaire was given to subjects containing questions on demographics and knowledge covering burden of rotavirus gastroenteritis, modes of transmission, age of occurrence, prevention, and rotavirus vaccines. Statistical analysis used: Data analysis was carried out with SPSS version 20. Results: Questionnaires were issued to 75 participants of which 65 (response rate = 86.7%) returned filled questionnaires. Majority (70.8%) of the subjects were females. Subjects included medical doctors (33.8%), nurses (32.3%), community health extension workers (27.7%), and laboratory scientists (4.6%). Most [39, 60.0%] subjects identified rotavirus as the commonest cause of diarrhea and only 21 (32.3%) indicated rotavirus contributed over 30% to the burden of diarrhea in these children. Fecooral route was recognized as a route of transmission by most subjects (95.4%) and 67.7% identified vaccination as a modality for prevention. Only six (9.2%) respondents could name any rotavirus vaccine. None of the demographic or occupational characteristics of the subjects was significantly related to awareness of effective rotavirus vaccines (all P > 0.05). Conclusions: Healthcare providers were aware of rotavirus as a cause of gastroenteritis in underfive children but most had poor understanding regarding its burden, prevention, and existing vaccines.
Micro-nutrient related malnutrition and obesity in a university undergraduate population and implications for non-communicable diseases Foluke A Olatona, Sunday A Aderibigbe, Eyitope O Amu, Oluseye O Onabanjo, Kelechi E Nnoaham Journal of Global Health Reports, 2020 Background Micronutrient deficiency and obesity are increasing globally. This study determined the prevalence of micronutrient-related malnutrition, patterns of obesity using different methods of assessment, and the predictors of obesity among the university undergraduate population in Lagos State, Nigeria. Methods A multistage sampling technique was adopted to select 506 students from the three universities in Lagos State. A pre-tested, semi-structured interviewer-administered questionnaire was used to obtain data on socio-demographic and economic characteristics. Nutrient intakes were estimated from 24-hour dietary recalls, obesity was assessed through anthropometric measurements and Bio-electrical Impedance Analysis, following standard procedures. Associations between variables were tested using Chi-square, Fischer’s exact tests, and logistic regression analyses. Twenty-four-hour diet recall was analyzed using the Total Diet Assessment soft-ware. Anthropometric indices were compared with World Health Organization (WHO) standards and classified. Results Mean daily intake of almost all micronutrients was low except sodium which was in excess compared to the recommended dietary allowances. The prevalence of underweight was 6.6%, overweight (16.4%), and obesity (3.2%) based on body mass index (BMI). Abdominal obesity was higher than general obesity. Obesity assessed using the percentage body fat had the highest yield of 54.4% in males and 37.1% in females. Conclusions Micronutrient-related malnutrition and central obesity were higher than reported in previous studies. Male gender, inconsistent income, and increased amount of folate were significant predictors of obesity. The students will benefit from nutrition education that emphasize the consumption of micronutrient dense foods and different methods of weight management.
Pediatric Bacterial Meningitis Surveillance in Nigeria from 2010 to 2016, Prior to and during the Phased Introduction of the 10-Valent Pneumococcal Conjugate Vaccine Beckie N Tagbo, Rowan E Bancroft, Iretiola Fajolu, Mohammed B Abdulkadir, Muhammad F Bashir, et al. Clinical Infectious Diseases, 2019 Background Historically, Nigeria has experienced large bacterial meningitis outbreaks with high mortality in children. Streptococcus pneumoniae (pneumococcus), Neisseria meningitidis (meningococcus), and Haemophilus influenzae are major causes of this invasive disease. In collaboration with the World Health Organization, we conducted longitudinal surveillance in sentinel hospitals within Nigeria to establish the burden of pediatric bacterial meningitis (PBM). Methods From 2010 to 2016, cerebrospinal fluid was collected from children <5 years of age, admitted to 5 sentinel hospitals in 5 Nigerian states. Microbiological and latex agglutination techniques were performed to detect the presence of pneumococcus, meningococcus, and H. influenzae. Species-specific polymerase chain reaction and serotyping/grouping were conducted to determine specific causative agents of PBM. Results A total of 5134 children with suspected meningitis were enrolled at the participating hospitals; of these 153 (2.9%) were confirmed PBM cases. The mortality rate for those infected was 15.0% (23/153). The dominant pathogen was pneumococcus (46.4%: 71/153) followed by meningococcus (34.6%: 53/153) and H. influenzae (19.0%: 29/153). Nearly half the pneumococcal meningitis cases successfully serotyped (46.4%: 13/28) were caused by serotypes that are included in the 10-valent pneumococcal conjugate vaccine. The most prevalent meningococcal and H. influenzae strains were serogroup W and serotype b, respectively. Conclusions Vaccine-type bacterial meningitis continues to be common among children <5 years in Nigeria. Challenges with vaccine introduction and coverage may explain some of these finding. Continued surveillance is needed to determine the distribution of serotypes/groups of meningeal pathogens across Nigeria and help inform and sustain vaccination policies in the country.
Asthma management and control in Nigeria: the asthma insight and reality Nigeria (AIRNIG) study Obianuju B. Ozoh, Adaeze C. Ayuk, Kingsley N. Ukwaja, Olufemi O. Desalu, Olajumoke Olufemi, et al. Expert Review of Respiratory Medicine, 2019 Background: The state of asthma management and asthma control at the population level in Nigeria is unknown. We aimed to determine the level of asthma control and asthma management practices in Nigeria. Methods: A cross-sectional population-based study of 405 participants with current asthma (physician-diagnosed with use of asthma medication or asthma symptoms in the preceding 12 months). We determined the level of asthma control, self-perception of asthma control, health-care use, missed work/school, and medication use. Results: Asthma was controlled in 6.2% of the participants. Night-time awakening and limitation in activity in the preceding 4 weeks were reported by 77.5% and 78.3%, respectively, 56.3% and 14.1% missed work/school and had emergency room visits, respectively, and 11.6% and 38.8% used inhaled corticosteroid and short-acting beta-2 agonist, respectively, in the preceding year. About a third (34.3%) had spirometry ever performed and 46.7% had training on inhaler technique. Nearly 90% with uncontrolled asthma had self-perception of asthma control between somewhat and completely controlled. Conclusion: The level of asthma control in Nigeria is poor with a high burden of asthma symptoms and limitation in activities. This calls for a broad-based approach for the improvement in asthma care that encompasses education and access to medications.
The prevalence of asthma and allergic rhinitis in Nigeria: A nationwide survey among children, adolescents and adults Obianuju B. Ozoh, Sunday A. Aderibigbe, Adaeze C. Ayuk, Olufemi O. Desalu, Olufela E. Oridota, et al. Plos One, 2019 Purpose Asthma is an important cause of morbidity and mortality worldwide and information on the prevalence of asthma in Nigeria is inconsistent. Nationally representative data, important for health planning is unavailable. We aimed to determine the current prevalence of asthma and allergic rhinitis in Nigeria. Materials and methods A cross-sectional population survey conducted between June 2017 and March 2018 across five cities representing five geo-political zones in Nigeria. Validated screening questionnaires were used to identify persons with asthma and allergic rhinitis respectively. Asthma was defined as physician diagnosed asthma, clinical asthma and by presence of wheeze in the last 12 months respectively. Socio-demographic information, tobacco smoking, sources of household cooking fuel were also obtained. Results A total of 20063 participants from 6024 households were screened. The prevalence (95% confidence interval) of physician diagnosed asthma, clinical asthma and wheeze was 2.5% (2.3–2.7%), 6.4% (6.0–6.64%) and 9.0% (8.6–9.4%) respectively. The prevalence of allergic rhinitis was 22.8% (22.2–23.4%). The prevalence of asthma and rhinitis increased with age (prevalence of clinical asthma: 3.1% (2.8–3.4%), 9.8% (9.1–10.5) and 10.7% (9.4%-12.0) among 6–17 years, 18–45 years and >45 years respectively). Prevalence also varied across different cities with the highest prevalence of clinical asthma occurring in Lagos (8.0%) and the lowest in Ilorin (1.1%). The frequency of allergic rhinitis among persons with clinical asthma was 74.7%. Presence of allergic rhinitis, family history of asthma, current smoking and being overweight were independent determinants of current asthma among adults. Conclusion The prevalence of asthma and allergic rhinitis in Nigeria is high with variabilities across regions and age groups. The number of persons with clinical asthma in Nigeria (approximately 13 million) is likely to rank among the highest in Africa. This warrants prioritization by stakeholders and policy makers to actively implement risk reduction measures and increase investment in capacity building for the diagnosis and treatment of asthma and allergic rhinitis.
Risk exposure to hepatitis B infection among senior secondary school students in a Metropolitan city of North-central Nigeria Ethiopian Journal of Health Development, 2016
Prevalence of heamoglobin genotype screening and awareness of SCD among undergraduate students of unilorin Journal of Medicine and Biomedical Research, 2016
Reference values of haematological parameters of healthy adults in the North Central zone of Nigeria East African Medical Journal, 2015
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Willingness to accept vaginal microbicides amongst students of university of ilorin Health Science Journal, 2011
Community awareness of bird flu and the practice of backyard poultry in a North-Central State of Nigeria Journal of Preventive Medicine and Hygiene, 2010
Awareness, attitude and practice towards indoor air pollution (IAP) amongst residents of Oke - Oyi in Ilorin Internet Journal of Epidemiology, 2010
Determinants of referral practices of clients by traditional birth attendants in Ilorin, Nigeria. African Journal of Reproductive Health, 2010
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A review of twin gestation in a tertiary health institution in North Central Nigeria Research Journal of Medical Sciences, 2009
Viral hepatitides in voluntary blood donors in Yola, Nigeria European Journal of Scientific Research, 2009
Syphilis in voluntary blood donors in North-eastern, Nigeria European Journal of Scientific Research, 2009
Hepatitis C virus and human immunodeficiency virus co-infection in North-Eastern Nigeria Research Journal of Medical Sciences, 2008
Effect of health education on sexual behaviour of students of public secondary schools in Ilorin, Nigeria European Journal of Scientific Research, 2008
Availability, adequacy and quality of water supply in ilorin metropolis, Nigeria European Journal of Scientific Research, 2008
Influence of drug promotion on prescribing habits of doctors in a teaching hospital. African Journal of Medicine and Medical Sciences, 2007
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