Agricultural and Biological Sciences, Materials Science, Biotechnology, Applied Microbiology and Biotechnology
FUTURE PROJECTS
Production and Storage of Nanomaterial-Mediated Biohydrogen
Applications Invited Collaborators
56
Scopus Publications
1322
Scholar Citations
18
Scholar h-index
23
Scholar i10-index
Scopus Publications
In-Silico Screening and Molecular Docking of Cinnamomum verum Phytochemicals Targeting the RyR2 N-Terminal Region in Ventricular Heart Arrhythmia Annals of Biology, 2026
Cinnamon as a phyto-therapeutic agent in ventricular heart Arrhythmia: Clinical and molecular perspectives Seema Puri, Gulab Singh, Yadvindra Singh, Chander Prakash, Anil Kumar, Shiv Kumar Giri, Gobind Ram Ram Environment Conservation Journal, 2026 Spice cinnamon (Cinnamomum spp.) is eaten worldwide and well documented scientifically because of its wide variety of bioactive compounds, such as eugenol, cinnamontannin B1, cinnamonaldehyde, cinnamozeynel, and others. These phytoconstituents show many pharmacological actions such as lipid-lowering, neuroprotectant, anti-inflammatory, antibacterial, antidiabetic, antioxidant, and anticancer. However, despite many benefits, the role of cinnamon in ventricular heart arrhythmia remains unstudied. This review addresses this major gap by incorporating clinical evidence (2020-2025) on the molecular mechanisms connecting bioactive compounds of cinnamon to calcium-mediated cardiac regulation and RyR2. The present review specializes in ventricular heart arrhythmia and calcium-dependent arrhythmogenic mechanisms, rather than previous reviews that largely cover general benefits in cardiac protection and metabolism of cinnamon. Using the disease-based synthesis from contemporary clinical and molecular information spanning the years 2020–2025, we report a new connection between cinnamon phytochemicals and RyR2 impairment and a link in RyR2-mediated intracellular Ca2+ mismanagement to ventricular electrical instability. It is this narrow focus that makes a difference in this review when compared to other research on cinnamon and heart health. In this review, we further discuss how cinnamaldehyde and its related compounds regulate ion-channel stability, inflammation, and oxidative stress by modifying several key cellular pathways such as NF-kB, Nrf2, MAPKs, and PI3K/Akt. We also try to point out the key hurdles that limit clinical use of cinnamon, such as long-term safety, differences among species (C. verum vs. C. cassia), and variation in active compounds. By analyzing these findings, we have tried to provide a clear understanding of how cinnamon acts as a natural approach to heart rhythm regulation. In this review, we have also pointed out the next steps, such as large-scale human trials that may turn this traditional herbal spice into a scientifically validated natural medicine for cardiac care.
Revealing the Insights of Molecular Nutrition in the Resilience of Muscle Strength Manpreet Kaur, Pramod Kumar, Gulab Singh Therapeutics and Molecular Nutrition, 2026 Muscle resilience is the capability to bounce back from an awful occurrence, including surmounting an array of constraints that have hindered an individual from carrying out their everyday tasks. To overcome these challenges, an understanding of molecular nutrition is vital to estimating the advantageous benefits of muscle training. Lifting a lighter weight, restricting blood flow, and failing to lift a heavy weight are responsible for muscle protein synthesis, which contributes to enhancing muscle endurance and strength. The aforementioned training workouts work in conjunction with the ingestion of high-quality proteins to sustain muscle endurance and strength. Over the years, there has been a lot of progress in revealing and understanding the facts that how strengthening workouts and nutrition collaborate together to build muscle mass and increase efficiency. Thus, the chapter will provide an overview of the insights from molecular nutrition about the adaptability of muscle mass and how to use it to improve training adaptation.
Stress Among Research Scholars: Causes, Coping Strategies and Implications for Policy Reform Saurabh Kumar, Gulab Singh, Anil Kumar, Shiv Kumar Giri Annals of Neurosciences, 2026 Background Stress is a major concern among research scholars as it has a detrimental effect on mental health, productivity and overall well-being. Several stressors, including academic pressure, financial issues, lack of resources and guide–student relationships, significantly contribute to the increased risk of lower physical and mental well-being in the long term. It is important to understand how stressors contribute to increased stress levels. Summary This study aimed to investigate the causes and consequences of stress, coping strategies in research scholars and policy implications of stress management. A literature search was performed using Google Scholar and PUBMED. This study included original research and review articles that were published in English. This study highlights academic pressure, lack of resources, guide–student relationships, future uncertainty, financial issues and work–life imbalance as major stressors for research scholars. Chronic stress decreases physical, mental, academic and professional outcomes. Key Message We propose adapting the ‘AAA strategy (approach, assessment and administration)’ by universities and institutes for stress management in research scholars. Policy changes in academic research are needed to improve research scholars’ overall productivity and quality of life.
Functional Foods: Emerging Aids Against Noncommunicable Disorders Anju Rani, Gulab Singh, Amita Suneja Dang, Shiv Kumar Giri, Neha Verma, Anil Kumar Therapeutics and Molecular Nutrition, 2026 In the last few decades, there has been an enormous surge in communicable as well as noncommunicable diseases (NCDs) that have globally affected the fatality rate. The primary reason for such a surge is changes in lifestyle especially in consumption habits. In this regard, to curb the increasing incidence of NCDs, consumers have shifted their interest to foods with balanced nutrition and as well as some therapeutic values. Nowadays, functional foods are gaining all the attention regarding prevention and reduction of NCDs as they possess various bioactivities. Functional foods have been classified into multiple categories depending on their source, such as plant-based (prebiotics), animal-based (bioactive compounds), marine-based (omega-3-fatty acid sources), and microbe-based (probiotics, prebiotics). These foods offer better therapeutic values than dietary supplements against various diseases and disorders. This chapter primarily focuses on the health benefits and the role of functional foods in the prevention and cure of noncommunicable disorders, such as cancer, diabetes, and neuropsychological and cardiovascular disorders. Recent findings and studies concerning health that are widely recognized as key to the impacts of functional foods have also been discussed.
Synergistic Role of Oxidative Stress and MIF Polymorphisms in Vitiligo Risk Annals of Biology, 2026
Synergistic Approaches for Navigating and Mitigating Agricultural Pollutants Swati Srivastava, Dheeraj Raya, Rajni Sharma, Shiv Kumar Giri, Kanu Priya, Anil Kumar, Gulab Singh, Saurabh Sudha Dhiman Pollutants, 2025 The alarming increase in the use of chemically driven pesticides for enhanced crop productivity has severely affected soil fertility, ecosystem balance, and consumer health. Inadequate handling protocols and ineffective remediation strategies have led to elevated pesticide concentrations, contributing to human respiratory and metabolic disorders in humans. In the current context, where agricultural activities and pesticide applications are intertwined, strong and sustainable remediation strategies are essential for environmental protection without sacrificing crop productivity. Various bio-inspired methods have been reported, such as phytoremediation, bioremediation, and in situ remediation; however, limited success has been observed with either single or combined approaches. Consequently, biopolymer biomanufacturing, nanoparticle-based bioengineering, and computational biology for improved understanding of mechanisms have been revisited to incorporate updated methodologies that detail the fate and action of harmful chemical pesticides in agriculture. An in silico mechanistic approach has been emphasized to understand the molecular mechanisms involved in agricultural pesticides’ degradation using nanomaterials. A roadmap has been created by integrating cutting-edge machine learning techniques to develop nature-inspired sustainable agricultural practices and contaminant disposal methods. This review represents a pioneering effort to explore the roles of wet-lab chemistry and in silico methods in mitigating the effects of agricultural pesticides, providing a comprehensive strategy for balancing environmental sustainability and agricultural practices.
Soil-microbe-plant continuum under ZnO and TiO₂ nanoparticle stress: An insight into toxicological implications, risk evaluation and management strategies Usha Kandhil, Gulab Singh, Anju Rani, Amita Suneja Dang, Shiv Kumar Giri, Saurabh Sudha Dhiman, Neha Verma, Anil Kumar Plant Nano Biology, 2025 Zinc oxide (ZnO) and titanium dioxide (TiO₂) are the most synthesized and widely used engineered nanoparticles. These can largely enter the plant and soil systems through anthropogenic sources related to their widespread industrial production and application. These nanoparticles influence the soil system by altering the physicochemical parameters and microbial functions, often leading to detrimental effects on the activity of key enzymes that ultimately impact plant health. Compared to information in a similar domain, our review aims to synthesize and analyse the recent developments across the soil-microbe-plant continuum under the stress of ZnO and TiO 2 NPs. Further, it integrates toxicological findings, mechanistic insights, risk assessment, and management strategies in one unified framework. The comprehensive reviews like this one may broaden the scientific understanding beyond fragmented findings, equipping the scientific community and stakeholders with the conceptual and practical tools needed to evaluate and manage nanoparticle-associated risks. Furthermore, by synthesizing evidence on long-term persistence, bioavailability, and ecological disruption across soil, microbes, and plants, this review offers guidelines for monitoring, remediation strategies, and safer usage of nanomaterials.
Plant Long Non-Coding RNAs (lncRNAs): An Updated Overview with Emphasis on the Regulation of Abiotic Stress Responses Heena Gulia, Neha Verma, Shiv Kumar Giri, Gulab Singh, Anil Kumar Epigenetics for Climate Smart and Sustainable Agriculture, 2025 Long non-coding RNAs (lncRNAs) in plants play a crucial role in mitigating various abiotic stresses, contributing to the better adaptation and survival of plants in challenging environments. These lncRNAs are involved in diverse mechanisms, including stress perception, epigenetic modifications, and gene regulation, that allow them to regulate various physiological processes, including stress signaling, osmotic regulation, ion homeostasis, and antioxidant defense mechanisms. Research indicates that lncRNAs can regulate stress-responsive genes, acting as molecular switches to modulate stress tolerance. Additionally, they participate in intricate regulatory networks, such as natural antisense transcripts (NATs), to fine-tune stress responses. Therefore, the characterization of stress-responsive lncRNAs and elucidation of their regulatory pathways hold immense potential for developing novel strategies to enhance plant resilience to environmental stresses. Furthermore, understanding the functions and regulatory mechanisms of plant lncRNAs provides insights into enhancing stress tolerance and crop productivity in the face of changing environmental conditions.
Cross talk between renal transporters and polycystin-1 as a potential molecular target involved in autosomal dominant polycystic kidney disease Iranian Journal of Kidney Diseases, 2021
Synthesis and characterization of magnetic imprinted polymer for selective extraction of cephalexin from food matrices Indian Journal of Chemical Technology, 2019
Aptamer: The science of synthetic DNA Abhishek Parashar, Munna Lal Yadav, Gulab Singh Yadav, Ram Krishan Saini Aptamers Biotechnological Applications of A Next Generation Tool, 2019
Environmental management by microbes through poly β-hydroxybutyrate production Microbiology and Biotechnology for A Sustainable Environment, 2017
Microbiology and biotechnology for a sustainable environment Microbiology and Biotechnology for A Sustainable Environment, 2017
The role of biotechnology in environmental sustainability Microbiology and Biotechnology for A Sustainable Environment, 2017
Isolation and cultural conditions optimization for poly CT-Hydroxybutyrate producing bacillus species Annals of Biology, 2012
Comparative nitrogen fixation by mesophilic (HTS) vis-à-vis thermotolerant mutants (HTR) of Azotobacter chroococcum at high temperature and their effect on cotton biomass Jundishapur Journal of Microbiology, 2011
Isolation and biochemical characterization of acido-thermophilic extracellular phytase producing bacterial strain for potential application in poultry feed Jundishapur Journal of Microbiology, 2011
RECENT SCHOLAR PUBLICATIONS
Stress among research scholars: causes, coping strategies and implications for policy reform S Kumar, G Singh, A Kumar, SK Giri Annals of Neurosciences 33 (1), 123-130 , 2026 2026 Citations: 7
Synergistic Approaches for Navigating and Mitigating Agricultural Pollutants S Srivastava, D Raya, R Sharma, SK Giri, K Priya, A Kumar, G Singh, ... Pollutants 5 (4), 37 , 2025 2025
Synergistic hydrolysis of lignocellulosic biomass using co-immobilization of tri-enzymes on chitosan-magnetite nanoparticle beads S Nagar, M Sindhu, K Kumari, V Kumar, G Singh, N Kharor, V Chugh, ... Preparative Biochemistry & Biotechnology 55 (9), 1208-1220 , 2025 2025
Soil-microbe-plant continuum under ZnO and TiO₂ nanoparticle stress: An insight into toxicological implications, risk evaluation and management strategies U Kandhil, G Singh, A Rani, AS Dang, SK Giri, SS Dhiman, N Verma, ... Plant Nano Biology, 100201 , 2025 2025 Citations: 3
Enhancing soybean growth under drought stress through bio-priming with desert endophyte Priestua endophytica strain RAE-11 M Choudhary, B Patel, M Patel, N Choudhary, S Bagatharia, RK Verma, ... Symbiosis 95 (3), 329-341 , 2025 2025 Citations: 3
Next-generation nanomaterials-based biosensors: Real-time biosensing devices for detecting emerging environmental pollutants M Sharma, P Mahajan, AS Alsubaie, V Khanna, S Chahal, A Thakur, ... Materials Today Sustainability 29, 101068 , 2025 2025 Citations: 113
Challenges and Sustainable Solutions for the Detection and Bioremediation of Microplastic Pollution: Challenges and Scope of Their Remediation From the Environment R Sharma, L Singla, G Singh Challenges and Sustainable Solutions in Bioremediation, 125-142 , 2025 2025 Citations: 3
Genetic polymorphism in Angiotensin-Converting Enzyme (ACE) and Asthma risk: A comparative meta-analysis based on Four gene model strategy K Priya, G Sharma, AS Dang, SK Giri, G Singh, SS Dhiman, A Kumar, ... Journal of Integrated Science and Technology 13 (2), 1033-1033 , 2025 2025
Nanomaterials mediated valorization of agriculture waste residue for biohydrogen production M Sindhu, R Sharma, A Saini, V Khanna, G Singh International Journal of Hydrogen Energy 52, 1241-1253 , 2024 2024 Citations: 23
Panorama of physico-mechanical engineering of graphene-reinforced copper composites for sustainable applications K Singh, V Khanna, A Rosenkranz, V Chaudhary, G Singh, S Rustagi Materials Today Sustainability 24, 100560 , 2023 2023 Citations: 31
Serendipitous discovery of a regioselective synthesis of novel benzoyloxy substituted phenyl/benzyl-sulfanyl/selenylbisesters, 3-benzoyloxy-3-(phenylsulfanyl)-β-lactams and … D Narula, SS Bari, G Singh, R Sharma, A Garg, A Bhalla Journal of Sulfur Chemistry 44 (6), 712-732 , 2023 2023 Citations: 6
The role of plant growth promoting rhizobacteria in strengthening plant resistance to fluoride toxicity: a review A Singh, VK Yadav, H Gautam, L Rathod, RS Chundawat, G Singh, ... Frontiers in Microbiology 14, 1271034 , 2023 2023 Citations: 18
Effect of various bio-deposition treatment techniques on recycled aggregate and recycled aggregate concrete H Sharma, SK Sharma, DK Ashish, SK Adhikary, G Singh Journal of Building Engineering 66, 105868 , 2023 2023 Citations: 61
Comparative study of ethanol production from sodium hydroxide pretreated rice straw residue using Saccharomyces cerevisiae and Zymomonas mobilis N Kumar, A Yadav, G Singh, A Singh, P Kumar, NK Aggarwal Archives of Microbiology 205 (4), 146 , 2023 2023 Citations: 28
Green synthesis of copper nanoparticles and their evaluation for antimicrobial activity and bio-compatibility S Choudhary, R Sharma, A Devi, A Thakur, SK Giri, S Nagar, G Singh Materials Today: Proceedings , 2023 2023 Citations: 11
Clove leaf-based magnesium nanoparticles synthesis for antimicrobial applications R Sharma, SK Giri, A Saini, S Nagar, G Singh Materials Today: Proceedings , 2023 2023 Citations: 5
Unraveling the importance of melatonin in the alleviation of metal-induced toxicity N Verma, SK Giri, G Singh, K Priya, A Kumar Biostimulants in Alleviation of Metal Toxicity in Plants, 295-319 , 2023 2023 Citations: 1
Antibiotics stress response of bacteria as mechanism of development of drug resistance R Sharma, A Thakur, A Saini, SK Giri, A Kumar, K Priya, G Singh Microbial stress response: Mechanisms and data science, 23-42 , 2023 2023 Citations: 5
Survival strategies and stress adaptations in halophilic Archaebacteria A Saini, A Kumar, G Singh, SK Giri Microbial stress response: mechanisms and data science, 1-21 , 2023 2023 Citations: 34
Impact of agrochemicals on soil microbiota SK Giri, N Verma, G Singh, R Gill, A Kumar Agrochemicals in Soil and Environment: Impacts and Remediation, 61-76 , 2022 2022 Citations: 2
MOST CITED SCHOLAR PUBLICATIONS
Isolation and screening of polyhydroxyalkanoates producing bacteria from pulp, paper, and cardboard industry wastes AK Bhuwal, G Singh, NK Aggarwal, V Goyal, A Yadav International journal of biomaterials 2013 (1), 752821 , 2013 2013 Citations: 264
Next-generation nanomaterials-based biosensors: Real-time biosensing devices for detecting emerging environmental pollutants M Sharma, P Mahajan, AS Alsubaie, V Khanna, S Chahal, A Thakur, ... Materials Today Sustainability 29, 101068 , 2025 2025 Citations: 113
Poly β ‐Hydroxybutyrate Production by Bacillus subtilis NG220 Using Sugar Industry Waste Water G Singh, A Kumari, A Mittal, A Yadav, NK Aggarwal BioMed research international 2013 (1), 952641 , 2013 2013 Citations: 113
Poly-β-hydroxybutyrate production and management of cardboard industry effluent by new Bacillus sp. NA10 AK Bhuwal, G Singh, NK Aggarwal, V Goyal, A Yadav Bioresources and Bioprocessing 1 (1), 9 , 2014 2014 Citations: 76
Isolation and biochemical characterization of acido-thermophilic extracellular phytase producing bacterial strain for potential application in poultry feed A Mittal, G Singh, V Goyal, A Yadav, K Aneja, S Gautam, N Aggarwal Jundishapur Journal of Microbiology 4 (4) , 2011 2011 Citations: 67
Optimization of poly-B-hydroxybutyrate production from Bacillus species G Singh, A Mittal, A Kumari, V Goel, NK Aggarwal, A Yadav European Journal of Biological Sciences 3 (4), 112-116 , 2011 2011 Citations: 66
Effect of various bio-deposition treatment techniques on recycled aggregate and recycled aggregate concrete H Sharma, SK Sharma, DK Ashish, SK Adhikary, G Singh Journal of Building Engineering 66, 105868 , 2023 2023 Citations: 61
Production of phytase by acido-thermophilic strain of Klebsiella sp. DB-3FJ711774. 1 using orange peel flour under submerged fermentation M Arpana, S Gulab, G Varsha, Y Anita, AN Kumar Innovative Romanian Food Biotechnology, 18-27 , 2012 2012 Citations: 55
Parametric Optimization of Cultural Conditions for Carboxymethyl Cellulase Production Using Pretreated Rice Straw by Bacillus sp. 313SI under Stationary and … V Goyal, A Mittal, AK Bhuwal, G Singh, A Yadav, NK Aggarwal Biotechnology research international 2014 (1), 651839 , 2014 2014 Citations: 52
Epigenetic regulation of heat and cold stress responses in crop plants N Verma, SK Giri, G Singh, R Gill, A Kumar Plant gene 29, 100351 , 2022 2022 Citations: 48
Cost Effective Production of Poly-β-Hydroxybutyrate by Bacillus subtilis NG05 Using Sugar Industry Waste Water G Singh, A Kumari, A Mittal, V Goel, A Yadav, NK Aggarwal Journal of Polymers and the Environment 21 (2), 441-449 , 2013 2013 Citations: 44
Spectroscopic, thermal, and antimicrobial studies of Co (II), Ni (II), Cu (II), and Zn (II) complexes derived from bidentate ligands containing N and S donor atoms K Singh, Y Kumar, P Puri, G Singh Bioinorganic Chemistry and Applications 2012 (1), 729708 , 2012 2012 Citations: 40
Survival strategies and stress adaptations in halophilic Archaebacteria A Saini, A Kumar, G Singh, SK Giri Microbial stress response: mechanisms and data science, 1-21 , 2023 2023 Citations: 34
Panorama of physico-mechanical engineering of graphene-reinforced copper composites for sustainable applications K Singh, V Khanna, A Rosenkranz, V Chaudhary, G Singh, S Rustagi Materials Today Sustainability 24, 100560 , 2023 2023 Citations: 31
Comparative study of ethanol production from sodium hydroxide pretreated rice straw residue using Saccharomyces cerevisiae and Zymomonas mobilis N Kumar, A Yadav, G Singh, A Singh, P Kumar, NK Aggarwal Archives of Microbiology 205 (4), 146 , 2023 2023 Citations: 28
Phytase: a boom in food industry A Mittal, V Gupta, G Singh, A Yadav, NK Aggarwal Octa Journal of Biosciences 1 (2) , 2013 2013 Citations: 26
Nanomaterials mediated valorization of agriculture waste residue for biohydrogen production M Sindhu, R Sharma, A Saini, V Khanna, G Singh International Journal of Hydrogen Energy 52, 1241-1253 , 2024 2024 Citations: 23
The role of plant growth promoting rhizobacteria in strengthening plant resistance to fluoride toxicity: a review A Singh, VK Yadav, H Gautam, L Rathod, RS Chundawat, G Singh, ... Frontiers in Microbiology 14, 1271034 , 2023 2023 Citations: 18
Synthesis and characterization of oxytetracycline imprinted magnetic polymer for application in food S Aggarwal, YS Rajput, G Singh, R Sharma Applied Nanoscience, 1-6 , 2015 2015 Citations: 18
Occupational health hazards and wide spectrum of genetic damage by the organic solvent fumes at the workplace: A critical appraisal N Verma, S Pandit, PK Gupta, S Kumar, A Kumar, SK Giri, G Yadav, ... Environmental Science and Pollution Research 29 (21), 30954-30966 , 2022 2022 Citations: 16