Ph.D. in Chemistry
Catalysis Division, CSIR-National Chemical Laboratory, Pune, INDIA
Duration: July 2006 - July 2011
Thesis: Three Way Catalytic Converter Reactions on Palladium Surfaces
Supervisor: Dr. C. S. Gopinath
Master of Science (M.Sc.) in Chemistry with 7.7/10 CGPA
The American College, Madurai, INDIA
Duration: June 2004 - April 2006
Project: Extraction and Chemical Modification of Gymnemic Acid from Gymnema Sylvestre and Complexation with Cr(III)
Supervisor: Dr. S. Prem Singh
Bachelor of Science (B.Sc.) in Chemistry with 68%
The American College, Madurai, INDIA
Duration: July 2001 - May 2004
1. Renewable Energy for Waste Management
Project: Feasibility and Implementation of Solar-Powered Garbage Trucks in Urban Tamil Nadu
Funding: INR 30 Lakhs, ICSSR-RMM-2024-3553
Role: Project Director
Applications Invited Research Associate
2. Biodegradable Packaging Materials
Project: Development of Ramie Fiber-Based Biodegradable Composites for Secondary Packaging Applications
Funding: INR 1,49,94 000
Role: Princciple investigator
Applications Invited Research Associate
43
Scopus Publications
618
Scholar Citations
15
Scholar h-index
21
Scholar i10-index
Scopus Publications
Salannin: A Versatile Triterpene from Neem with Therapeutic Potential Phytoconstituents of the Neem Plant Pharmacological Activities and Applications, 2025
Impact of fluoride on thyroid function and histopathology in cyprinus carpio: Implications for aquatic ecosystems Jai Sankar, Yesudass Thangam, Sivaprakasham Umamaheswari, Shanmugam Kowsalya, K.M. Syed Ali Fathima, Raman Sathyavathi, Lenin Suvetha, Ekambaram Gayathiri, Palanisamy Prakash, Sankaranarayanan Nagarajan Toxicology Reports, 2025 Fluoride pollution in freshwater bodies is becoming alarming because it interferes with the endocrine system of water-dwelling organisms. In this study, we evaluated the effects of sublethal fluoride levels on thyroid hormone levels and histological alterations in Cyprinus carpio, a popular model fish species used in ecotoxicity experiments. The low, medium, and high fluoride groups received 1, 5, and 10 mg/L fluoride, respectively, and thyroxine plasma levels (T4) and triiodothyronine plasma levels (T3) were assessed at 7, 14, 21, and 35 days. The findings revealed that both T4 and T3 levels significantly decreased with increasing dose and ranged from to 10-41 % lower than controls in the 10 mg/L fluoride group. On day 35, T4 levels were reduced by 42 % and T3 levels were reduced by 50 % in the high fluoride exposure group compared to those in the control group. Changes in the thyroid gland were observed under a light microscope that included, but were not limited to, small follicle size, epithelial hypertrophy, and epithelial hyperplasia, especially in the high-fluoride group. These results suggest that elevated fluoride exposure causes a hormonal imbalance in Cyprinus carpio by affecting thyroid hormone biosynthesis and functionality, which may result in growth and reproductive failure. The eminent dose-response data on fluoride concentration and the degree of thyroid disruption clearly emphasise the severe endocrine-disruptive effects of fluoride at increased concentrations. The results of the present study agree with those of other studies that have described the inhibitory effect of fluoride on thyroid function in different fish species. Therefore, we conclude that fluoride may be a potent endocrine disruptor in the environment. As thyroid hormones play significant roles in metabolic and physiological functions in fish, these findings underscore the importance of improving fluoride standards in freshwater habitats. Research on the molecular pathways that lead to thyroid dysfunction when exposed to fluoride and other effects of this chemical substance on the environment.
Integrative nutrition strategies and cardiovascular therapy from macronutrients to micronutrients Gayathiri Ekambaram, Nagarajan Sankaranarayanan, Prithiviraj Nagarajan, Prakash Palanisamy, Thenmozhi Mani, Vinoth Raman, Ramachandran Kaliaperumal, Leena Rajathy Port Louis, Sharangouda J. Patil Impact of Yoga and Proper Diet on Cardiopulmonary Function, 2024 Cardiovascular health remains a concern for individuals' health, and nutrition has a major influence on how this issue can be addressed and solved. This chapter provides a thorough interlocution of nutritional interventions that are supposed to improve cardiovascular health and their theoretical application in the cardiovascular management of patients. Therefore, assessing the effects of consuming different dietary components will help to form a coherent picture of how nutrition affects heart disease and contributes to the therapeutic process. To commence with the analysis of the different macronutrients, carbohydrates, proteins, and fats were defined together with their places in cardiovascular functionality. We explored the advantages of proper macronutrient distribution, which requires prioritizing excellent protein, carbohydrate, and fat sources including whole grains, lean meats, and omega-3 fatty acids. In addition, we focused on the negative effects of refined sugars and trans fats, drawing a relationship with cardiovascular diseases.
RECENT PROGRESS IN THE SYNTHESIS AND PHOTOCATALYTIC DEGRADATION OF ORGANIC POLLUTANTS BY GRAPHENE-BASED TiO2 NANOCOMPOSITE: A REVIEW LEIVON CHUNGKHOLEN KOM, HENAM PREMANANDA SINGH, SANKARANARAYANAN NAGARAJAN Surface Review and Letters, 2024 Numerous sustainable water processing techniques have been widely investigated and are capable of boosting the quality of water. Among these techniques, photonanocatalysis has stood tall with great promises in the last few decades. Nonetheless, a major challenge in the environmental remediation of photocatalyst technology is to develop an ideal photocatalyst that must have excellent photocatalytic efficiency, large specific surface area, maximum harvesting of solar energy, high durability and recyclability. Due to their stability, low toxicity, low cost and superhydrophilicity TiO2 has been used by researchers as an efficient photocatalyst for the degradation of organic pollutants. Unfortunately, it suffers greatly due to its high band gap with 3.2[Formula: see text]eV, insufficient visible light response, fast photogenerated electrons and holes recombination rate and serious agglomeration. Keeping these views, the present review highlights the principal results of studies on current practical synthesis and photocatalytic activity of graphene-based TiO2 nanocomposite materials for the treatment of water. The amalgamation of graphene oxide (GO) and reduced graphene oxide (rGO) with nanoscale TiO2 particles results in synergistic properties thereby tuning and increasing the functionality of the composite. In this regard, the review also addressed the progress and insight into graphene-based TiO2 nanocomposite in photocatalytic removal of organic pollutants including basis mechanism, possible key strategies of the composite, and an overview of how to elevate efficacy. Finally, brief challenges and future perspectives in this field are also presented. Indeed, this work illustrated that graphene-based TiO2 composite nanomaterials can be a green signal in the future of photocatalysis targeting water pollution remediation.
Facile Greener Synthesis of CoTiO3/TiO2 Composite Nanocatalysts: Understanding the Origin of Synergistic Effect Leivon Chungkholen Kom, Henam Sylvia Devi, Henam Premananda Singh, Sankaranarayanan Nagarajan Kinetics and Catalysis, 2024 Abstract Understanding the composition-activity relationship is essential for exploiting the synergistic properties of composite nanomaterials in catalytic processes. This article provides insights into the origin of the synergistic effect in composite nanocatalysts by constructing different compositions of well-defined CoTiO3/TiO2 nanoparticles (NPs) with various Ti : Co weight ratios of 2 : 1 (C1) and 1 : 1 (C2). An environmentally benign method utilizing aqueous cinnamon extract was employed for the catalyst preparations. Catalytic tests for the reductive degradation of Congo Red and rhodamine B dyes reveal an activity order of C1 > C2 > TiO2 NPs, suggesting possible surface reconstruction in the composite nanocatalytic system. Detailed structural and compositional analyses indicate that the exceptional catalytic performance of C1 NPs is closely related to synergistic electronic and strain effects. This synergistic effect in composite NPs can be optimized by adjusting the ratio of constituents, which is anticipated to play a more crucial role in catalysis than particle size. Furthermore, the composite C1 NPs exhibit remarkable robustness, maintaining recyclability up to the fifth cycle with only an 8.51% loss in performance.
Silver nanoparticles biosynthesis from Ficus pomifera, Strobilanthes flaccidifoliuss, and Crassocephalum crepidioides plant extracts Wangkheirakpam Sujata, Warjeet Singh Laitonjam, Purnima Laishram, Nagarajan Sankaranarayanan, Anish Khan, Mohamed Hashem, Hassan Fouad Results in Chemistry, 2024 This research can potentially impact the silver nanoparticle synthesis field significantly. The study describes the synthesis and tentative mechanism involved in silver nanoparticles with bioactives compounds 1, 2, 3, and 4 (cyclopentane derivative, polyol, Indigo, and polymer), characterized isolates from Ficus pomifera Wall, Strobilanthes flaccidifolius Nees and Crassocephalum crepidioides (Benth.) Moore. The findings of this research, particularly the characterization of silver nanoparticles formed with three compounds using energy-dispersive X-ray analysis, X-ray diffraction, transmission electron microscopy, FTIR, and UV–Vis spectroscopy, could pave the way for future advancements in the field. The average size was reported to be 50 nm, 16 nm, and 61 nm, respectively, for compounds 1, 3, and 4. Tentative mechanisms were developed for the formation of the nanoparticles by each compound 1, 3, and 4. Compound 1 reduced silver after dehydration, evident from a new ester carbonyl peak at 1743 nm from the IR spectrum. Compound 2 failed to reduce silver ions.
Antioxidant, Diabetic and Inflammatory Activities of Alpinia calcarata Roscoe Extract Naorem Manglembi Devi, Sankaranarayanan Nagarajan, Chingakham Brajakishor Singh, Mohammad Mujahid Ali Khan, Anish Khan, Nisha Khan, Mohamed H. Mahmoud, Hassan Fouad, AbuZar Ansari Chemistry and Biodiversity, 2024 Background: Alpinia calcarata (AC) Roscoe of Zingiberaceae popularly known as lesser galangal has a widespread occurrence in China, India, Sri‐Lanka, Bangladesh, Malaysia, Indonesia and Thailand. Essential oil (Eoil) was obtained from leaves/rhizomes of AC via hydro‐distillation process. Methods: To identify chemical ingredients in oil from leaves/rhizomes of AC through GC/MS technique for volatile components and their anti‐oxidant, inflammatory/diabetic activities. Results: The 38 and 65 components were found to make up 99.9 and 99.6 %, respectively in total of Eoil composition of AC leaves/rhizomes. Key chemical constituents were eucalyptol (28.7 % in leaves; 25.4 % in rhizomes), camphor (12.8 % in leaves; 4.2 % in rhizomes), and carotol (9.8 % in leaves; 5.6 % in rhizomes) found in oil of AC leaves/rhizomes. Colorimetric assay showed anti‐oxidant activities in leaves and rhizomes are IC50=71.01±0.71 μg/mL and IC50=73.83±0.49 μg/mL, respectively in the Eoils. Eoils had high anti‐oxidant capabilities in IC50‐values of AC‐L‐Eoil=43.09±0.82&AC‐Rh‐Eoil=68.11±0.87 in reducing power in μg/mL was found. Albumin test of rhizome oil had IC50‐values of 15.19±0.25 μg/mL. Concentrations range of 7.81 μg/mL and 250 μg/mL in the Eoils of AC leaves and rhizome, respectively by α‐glucosidase inhibition assay. Conclusion: Our findings demonstrated that leaf oil was slightly more promising results than rhizome oil of AC extract, which was ultimately showed medicinal potential of secondary metabolites with anti‐oxidant, diabetic/inflammatory activities. Further, Eoils of AC have a wide range of pharmacological potential and promising anti‐diabetic effects.
Diffusion of chemisorbed oxygen into Pd sub-surfaces and its influence in oxidation catalysis Journal of the Indian Institute of Science, 2010
Carbon dissolution and segregation in Pd(110) Michael Bowker, Jonathan Counsell, Kareem El-Abiary, Lee Gilbert, Chris Morgan, Sankaranarayanan Nagarajan, Chinnakonda S. Gopinath Journal of Physical Chemistry C, 2010
Phytoconstituents: A Promising Avenue for Diabetic Foot Ulcer Management KR Prithiviraj Nagarajan, Deepa Shanmugam, Gayathiri Ekambaram, Suganya ... Harnessing Phytoconstituents for Wound Healing, 309-366 , 2026 2026
Exploring the Identification of PKB/Akt and Its Interaction with Docking, Molecular Dynamics Simulations, and Physiochemical Properties in the Echinocystic Acid Complex SD Priyadharshini, E Gayathiri, T Pratheep, K Selvam, S Nagarajan, ... In Silico Research in Biomedicine, 100237 , 2026 2026
Exploring the therapeutic potential of Annona reticulata extract: molecular docking, dynamics, and ADMET properties for cancer treatment and anti-inflammatory … P Thangaraj, E Gayathiri, P Prakash, D Viswanathan, M Rahaman, ... Journal of Asian Natural Products Research 27 (5), 709-731 , 2025 2025 Citations: 8
Ethical Issues and Safety Features of Nanomaterials in Food Packaging PP Nagarajan S, E. Gayathiri, P. Nagarajan , S.J. Patil Nanotechnology in Food Packaging, 115-166 , 2025 2025 Citations: 1
Impact of fluoride on thyroid function and histopathology in cyprinus carpio: Implications for aquatic ecosystems SN Jai Sankar, Yesudass Thangam, Sivaprakasham Umamaheswari, Shanmugam ... Toxicology Reports 14, 101964 , 2025 2025 Citations: 6
Lanthanum oxide nanoparticles synthesis using plant extracts: a greener approach AA M. V. Perumal, S. Nagarajan, G. Kanthimathi, T. Usharani Journal of Molecular and Engineering Materials , 2025 2025
Integrative Nutrition Strategies and Cardiovascular Therapy From Macronutrients to Micronutrients SJP Gayathiri Ekambaram, Nagarajan Sankaranarayanan, Prithiviraj Nagarajan ... Impact of Yoga and Proper Diet on Cardiopulmonary Function, DOI: 10.4018/979 … , 2025 2025
In-vitro study to evaluate anti-oxidant, diabetic and inflammatory potentials of rhizomes of Zingiberaceae N Devi, S Nagarajan, C Singh, L Khongsai, W Chanu, A Somya, ... Authorea 7, 1 , 2024 2024
Facile Greener Synthesis of CoTiO 3 /TiO 2 Composite Nanocatalysts: Understanding the Origin of Synergistic Effect LC Kom, HS Devi, HP Singh, S Nagarajan Kinetics and Catalysis 65 (6), 818-831 , 2024 2024
Bio-fiber recovery from industrially discarded shoot waste ( Cymbopogon nardus ): a comprehensive study for reinforcement in sustainable composites D Malathi, AK Pulikkal, MT Ramesan, S Nagarajan Biomass Conversion and Biorefinery 14 (16), 19081-19092 , 2024 2024 Citations: 10
Silver nanoparticle biosynthesis from Ficus pomifera, Strobilanthes flaccidifoliuss, and Crassocephalum crepidioides plant extracts HF W. Sujata, W. S. Laitonjam, P. Laishram, S. Nagarajan, A. Khan, M. Hashem Results in Chemistry , 2024 2024 Citations: 1
Green Synthesis of Copper Nanoparticles Using Flower Extracts: A Promising Route for Enhanced Microelectronics Packaging TU M. Venkatesh Perumal, S. Nagarajan, R. Srinivasan, K. Jayamoorthy Journal of Molecular and Engineering Materials , 2024 2024 Citations: 1
Recent progress in synthesis and photocatalytic degradation of organic pollutants by graphene based TiO2 nanocomposite: A review SN L.C. Kom, H. P. Singh Surface Review and Letters , 2024 2024 Citations: 1
Mercerized Cymbopogon nardus shoot fiber as reinforcing filler P Durgamalathi, AK Pulikkal, MT Ramesan, S Nagarajan Materials Chemistry and Physics 313, 128739 , 2024 2024 Citations: 9
Effective design and implementation of hybrid renewable system using convex programming J De Britto C, S Nagarajan, RS Kumar International Journal of Green Energy 20 (13), 1473-1487 , 2023 2023 Citations: 6
Anti-oxidant, Diabetic Inflammatory Activities of Alpinia Calcarata Roscoe Extract AA N. M. Devi, S. Nagarajan, C. B. Singh, M. M.A. Khan, A. Khan, N. Khan, M ... Chemistry and Biodiversity , 2023 2023 Citations: 7
Nickel-Manganese bimetallic Selenide as an electrode for supercapcitor applications AM S. Saranya, S. Dhanapandian, S. Suthakaran, S. Nagarajan, N. Krishnakumar ... Sustainable Energy Technologies and Assessments 59 (Oct 2023), 103376 , 2023 2023 Citations: 15
Evaluation of potential antioxidant and effect of biomimetic nanoscale silver particles on opportunistic fungi SN N.M.Devi, N. Bhogenjit, H. P. Singh, C. B. Singh Journal of Indian Chemical Society 100 (2), 1008 , 2023 2023
Fabrication of Vacuum Evaporated (Cu1-xAgx)2ZnSnSe4 Thin-film Photovoltaic Devices and its Photoconversion Efficiency GSKM J. Henry, S. Nagarajan Arabian Journal for Science and Engineering 48, 291-309 , 2022 2022 Citations: 2
In-situ formation of 2H phase MoS2/cerium-zirconium oxide nanohybrid for potential electrochemical detection of an anticancer drug flutamide CCH S.V.Selvi, N.Nataraj, T.-W.Chen, S.M.Chen, S.Nagarajan, C.S.Ko T.-W.Tseng Materials Today Chemistry 23, 100749 , 2022 2022 Citations: 25
MOST CITED SCHOLAR PUBLICATIONS
Investigation on the mechanical properties of ramie/kenaf fibers under various parameters using GRA and TOPSIS methods SPG Saikrishnan Ganesh, Sumesh Keerthiveettil Ramakrishnan, Vijayanand ... Polymer Composites 43, 130-143 , 2021 2021 Citations: 51
Suitability Evaluation of Sida Mysorensis Plant Fiber as Reinforcement in Polymer Composite SS M Maran, R Kumar, P Senthamaraikannan, SS Saravanakumar, S Nagarajan, MR ... Journal of Natural Fibers 19 (5), 1-11 , 2020 2020 Citations: 51
A revisit to carbon monoxide oxidation on Pd (111) surfaces S Nagarajan, K Thirunavukkarasu, CS Gopinath The Journal of Physical Chemistry C 113 (17), 7385-7397 , 2009 2009 Citations: 48
Mechanical and Thermal Properties of Chloris barbata flower fiber /Epoxy Composites: Effect of Alkali treatment and Fiber weight fraction SN B. Muthu chozha rajan ,S. Indran,D. Divya,P. Narayanasamy, Anish Khan ... Journal of Natural Fibers, 10.1080/15440478.2020.1848703 , 2020 2020 Citations: 44
Ion-solvation-induced molecular reorganization in liquid water probed by resonant inelastic soft X-ray scattering YL Jeyachandran, F Meyer, S Nagarajan, A Benkert, M Bär, M Blum, ... The journal of physical chemistry letters 5 (23), 4143-4148 , 2014 2014 Citations: 42
Can we shift and/or broaden the catalysis regime towards ambient temperature? CS Gopinath, K Roy, S Nagarajan ChemCatChem 7 (4), 588-594 , 2015 2015 Citations: 34
“Building block picture” of the electronic structure of aqueous cysteine derived from resonant inelastic soft X-ray scattering F Meyer, M Blum, A Benkert, D Hauschild, S Nagarajan, RG Wilks, ... The Journal of Physical Chemistry B 118 (46), 13142-13150 , 2014 2014 Citations: 30
Corrosion inhibitive evaluation and DFT studies of 2-(Furan-2-yl)-4,5-diphenyl-1H-imidazole on mild steel at 1.0 M HCl NR Loganathan K. T, Venkatesan S., Thimmakondu, Nagarajan. S Journal of the Indian Chemical Society 98 (9), 100121 , 2021 2021 Citations: 28
Kinetic evidence for the influence of subsurface oxygen on palladium surfaces towards CO oxidation at high temperatures CS Gopinath, K Thirunavukkarasu, S Nagarajan Chemistry–An Asian Journal 4 (1), 74-80 , 2009 2009 Citations: 26
In-situ formation of 2H phase MoS2/cerium-zirconium oxide nanohybrid for potential electrochemical detection of an anticancer drug flutamide CCH S.V.Selvi, N.Nataraj, T.-W.Chen, S.M.Chen, S.Nagarajan, C.S.Ko T.-W.Tseng Materials Today Chemistry 23, 100749 , 2022 2022 Citations: 25
Carbon dissolution and segregation in Pd (110) M Bowker, J Counsell, K El-Abiary, L Gilbert, C Morgan, S Nagarajan, ... The Journal of Physical Chemistry C 114 (11), 5060-5067 , 2010 2010 Citations: 24
Influence of premixed dual metal sulfides on the tribological performance of copper-free brake friction materials LSD Vijay R., Manoharan S., Nagarajan S. Industrial Lubrication and Tribology 73 (2), 266-274 , 2020 2020 Citations: 21
Hydrothermal Synthesis and Characterization of Nanostructured Nickel Diselenide (NiSe2) from the Decomposition of Nickel Acetate Tetrahydrate (Ni(CH3COO)2).4H2O NK S. Saranya, S. Dhanapandian, S. Nagarajan, S. Suthakaran Materials letters 277, 128398 , 2020 2020 Citations: 21
An insight into the effect of composition for enhance catalytic performance of biogenic Au/Ag bimetallic nanoparticles SN Dhaneshor Leishangthem, Md. Amar Khan Yumkhaibam, Premananda Singh Henam Journal of Physical Organic Chemistry , 2018 2018 Citations: 17
Nickel-Manganese bimetallic Selenide as an electrode for supercapcitor applications AM S. Saranya, S. Dhanapandian, S. Suthakaran, S. Nagarajan, N. Krishnakumar ... Sustainable Energy Technologies and Assessments 59 (Oct 2023), 103376 , 2023 2023 Citations: 15
Nitric Oxide Reduction with Ethanol on Palladium Surfaces: A Molecular Beam Study S Nagarajan, K Thirunavukkarasu, CS Gopinath, J Counsell, L Gilbert, ... The Journal of Physical Chemistry C 113 (22), 9814-9819 , 2009 2009 Citations: 15
Anticancer activity of Mahonia leschenaultii methanolic root extract and berberine on Dalton’s ascitic lymphoma in mice R Latha, TMC Rajanathan, A Khusro, N Chidambaranathan, P Agastian, ... Asian Pacific Journal of Tropical Medicine 12 (6), 264-271 , 2019 2019 Citations: 14
Diffusion of chemisorbed oxygen into Pd sub-surfaces and its influence in oxidation catalysis S Nagarajan, CS Gopinath Journal of the Indian Institute of Science 90 (2), 245-260 , 2010 2010 Citations: 11
Bio-fiber recovery from industrially discarded shoot waste ( Cymbopogon nardus ): a comprehensive study for reinforcement in sustainable composites D Malathi, AK Pulikkal, MT Ramesan, S Nagarajan Biomass Conversion and Biorefinery 14 (16), 19081-19092 , 2024 2024 Citations: 10
Structural, optical and electrical properties of undoped and doped ZnO thin films LB Chandrasekar, S Nagarajan, M Karunakaran, TD Thangadurai 2D Materials , 2019 2019 Citations: 10
GRANT DETAILS
Subsurface Oxygen and its Effect on Catalytic Processes for Environmental Pollution Applications
Funding: Approximately INR 30 Lakhs under the Early Career Researcher (ECR) scheme by DST-SERB
Duration: 3 years
