2D Nanomaterials for Drug Delivery System Syed Muzammil Munawar, Dhandayuthabani Rajendiran, Kaleel Basha Sabjan 2d Nanomaterials Synthesis Properties and Applications, 2024 Activation of drug structure at the nanometer level can prolong drug loading time, increase drug biotransport, and increase drug uniformity, thereby reducing drug toxicity and improving efficacy. Consequently, nanostep structures for drug delivery in the clinical discipline have attracted increasing interest, which has generated tremendous momentum just like ordinary pharmaceutical companies, biomedical and pharmaceutical companies have invested a great deal of money, energy and time in researching effective nanocarriers structure, 2D substances are of great interest because of their unique residence times in physical and chemical environments and their broad potential for applications in devices, biosensing, medicine, energy, and catalysis. The two multidimensional substances also have excellent drug delivery abilities compared to the conventional drug delivery structures. The main function of the 2D substance is the ultrafine nanogrid structure intentionally attached to the specific massive area of the ground thick structure for various external stimuli, 2D substances can exist as extremely green photodynamic and photothermal remedies for ailments. In addition, two-dimensional nanomaterial layer systems offer immense space for highly ecological medicines. Meanwhile, 2D substances with 2D terrain-changing material can have vivid orientation. Drugs can be properly stacked, and the effects of drugs can be reduced. However, NIR reaction, pH reaction with two-dimensional substances, two-dimensional SDDS can properly dispense tablets and effectively control blood consciousness to achieve great healing potential. These residences offer the possibility of multimodal healing of the disease. These special blessings are making 2D substance research more popular in the SDDS. However, it needs to be done much faster than can be accomplished in scientific exercises, but there are pressing issues that need to be addressed, including the transient long-term degradability and long-term toxicity of 2D materials. In addition, they study 2D substances in vitro , which are reserved for terrestrial animals, and in vitro experiments are also an important step towards their scientific implementation. Further intensive research and further in vivo experiments are expected to eventually implement SDDS-derived 2D coated compound packages as part of a scientific exercise. In this chapter we highlight the recent SDDS improvements, which are huge a wide range of 2D sensitive substance companies consisting of micelles, polymers, liposomes, hydrogels, nanofilms, nanoparticles, etc . Large organic packaging of 2D substances in 2D substances modified to be pharmaceutical companies function. 2D Stuff because pharmaceutical companies can improve disease drug treatment outcomes through managed launch, sustained launch, and stepped forward drug targeting. Therefore, 2D substances are perfectly suited to enhance the following SDDS technology.
Artificial intelligence and IoT: Challenges and future directions for data-driven system Syed Muzammil Munawar, Dhandayuthabani Rajendiran, Khaleel Basha Sabjan Artificial Intelligence and Internet of Things Based Augmented Trends for Data Driven Systems, 2024 Researchers and developers from all around the world are interested in recent developments in Internet of Things (IoT). IoT researchers and developers are collaborating to advance technology on a big scale and benefit society as much as possible. However, advancements are only feasible if we take into account the various problems and shortfalls in the current technical approaches. In this chapter, we discuss a number of problems and difficulties that IoT developers must consider while creating a better model. Important IoT application areas are also covered, including those where IoT researchers and developers are working. The IoT produces not only services but also a tonne of data. Consequently, the significance of big data analytics is also discussed because it can deliver precise decisions that could.
Kinetics and adsorption performance of biosorbent starch/poly(vinyl alcohol)/graphene oxide nanocomposite for the removal of dyes V. Shanmuga Priya, S. Khaleel Basha, V. Sugantha Kumari Journal of Umm Al Qura University for Applied Sciences, 2023 The present work reports an efficient removal of a cationic dye, methylene blue (MB), and an anionic dye, methyl orange (MO) dye from an aqueous solution using graphene oxide (GO)–based nanocomposite as an adsorbent. GO was investigated as a potential nano-reinforcing filler in starch/poly(vinyl alcohol) (PVA) biopolymer matrix. Bio-nanocomposite based on starch/PVA matrix and GO were prepared by an aqueous casting method. The fabricated nanocomposites were characterized using FT-IR, XRD, Raman, TEM, FE-SEM, tensile study, Brunauer–Emmett–Teller (BET) method, Barrett–Joyner–Halenda (BJH) method, zeta potential, and swelling study. The effect of the various compositions of GO nanofiller in the starch/PVA matrix was highlighted and the impact of GO nanosheets on the properties of the nanocomposites was revealed. The results demonstrated that the starch/PVA matrix with 3 g of GO was found to be the optimal concentration of GO. Batch adsorption experiments were conducted to optimize the operational factors, including adsorbent dosage, pH, and contact time, which were systematically investigated. The kinetics of adsorption followed a pseudo-second-order model, while the Langmuir isotherm model described the equilibrium adsorption capacity. The prepared nanocomposite exhibited a maximum monolayer adsorption capacity of 382 mg g−1 for MB dye and 293.3 mg g−1 for MO dye. Based on the calculated thermodynamic parameters for the adsorption of MB (∆H° = − 16.37 kJ mol−1, ∆S° = − 37.99 J K−1 mol−1 and ∆G° from − 4.39 to − 5.13 kJ mol−1) and MO (∆H° = − 13.72 kJ mol−1, ∆S° = − 31.78 J K−1 mol−1 and ∆G° from − 3.72 to − 4.39 kJ mol−1) dyes onto the nanocomposite material was feasible, exothermic, and spontaneous. A plausible adsorption mechanism was proposed, involving electrostatic attraction, H-bonding, and π-π interactions, which collectively governed the adsorption process. The nanocomposite showed good stability and reusability up to five cycles for the uptake of MB and MO dyes. These findings confirmed the effectiveness of the proposed approach to produce bionanocomposite with enhanced properties, which may be used in water purification technology.
In vitro cytocompatibility evaluation of nanostarch reinforced polyaniline-polyvinyl alcohol conductive bionanocomposites for skin tissue engineering application D. Switha, S. Khaleel Basha, V. Sugantha Kumari Journal of Umm Al Qura University for Applied Sciences, 2023 In this study, we aimed to fabricate nanostarch (NS) reinforced polyaniline/polyvinyl alcohol (PANI-PVA) bionanocomposite of polyaniline-polyvinyl alcohol-nanostarch for skin tissue engineering application. The microstructure of the bionanocomposite was analyzed using TEM and the particle size ranged from 35 to 37 nm. The swelling degree was increased with the increase in the concentration of nanostarch and displayed a greater hydrophilic surface leading to the increase in the absorption. The degradation index analysis was recorded with an increase in the weight loss of the scaffold which attributed to a strong hydrogen bond network. The bionanocomposites exhibited 70% to 82% of cytocompatibility towards L929 cells during the incubation period of day 1, day 4 and day 7. Hence, the novel bionanocomposite with the features of enhanced water-holding capacity, weight loss percentage and cytocompatibility made it suitable for the prospective use in skin tissue engineering applications. Graphical abstract
Camel Ghee: Nutritional Value and Health Aspects Syed Muzammil Munawar, Khaleel Basha Sabjan, Aafrin Waziri, Meena Bhandari, Renu Kadian, Md Sabir Alam Ghee Chemistry Technology and Health Aspects, 2023
Trends in Theranostic Applications of Metallic Nanoparticles Md Sabir Alam, Mansi Garg, Vijay Bhalla, Puja Kumari, Renu Kadyan, Md Meraj Anjum, Tejpal Yadav, Madhu Yadav, Mukesh Kumar, Aafrin Waziri, Syed Muzammil Munawar, Dhandayuthabani Rajendiran, Khaleel Basha Sabjan, Jamilur R. Ansari Metallic Nanoparticles for Health and the Environment, 2023
Nanoemulsion as oral drug delivery-a review Khaleel Basha Sabjan, Syed Muzammil Munawar, Dhandayuthabani Rajendiran, Sugantha Kumari Vinoji, Kaviyarasu Kasinathan Current Drug Research Reviews, 2020
Multiple herbal therapy - antimicrobial activity of wound healing paste(Pasuru) used by Sugali tribes of Yerramalais of Kurnool District.,Andhra Pradesh,India International Journal of Pharmtech Research, 2011
Bio-inspired Chitosan/poly (vinyl Alcohol)/nanobioactive Glass/functionalized Carbon Nanotube Scaffold for Bone Tissue Engineering PN Christy, SK Basha, VS Kumari Silicon, 1-19 , 2026 2026
Sustainable removal of hexavalent chromium using graphene oxide-Iron oxide reinforced pectin/polyvinyl alcohol magnetic gel beads VS Priya, SK Basha, VS Kumari International journal of biological macromolecules 257, 128542 , 2024 2024 Citations: 17
Kinetics and adsorption performance of biosorbent starch/poly (vinyl alcohol)/graphene oxide nanocomposite for the removal of dyes VS Priya, SK Basha, VS Kumari Journal of Umm Al-Qura University for Applied Sciences 9 (4), 529-547 , 2023 2023 Citations: 31
Fabrication of conductive hybrid scaffold based on polyaniline/polyvinyl alcohol–chitosan nanoparticles for skin tissue engineering application D Switha, SK Basha, VS Kumari Polymer Bulletin 80 (10), 11439-11467 , 2023 2023 Citations: 13
Assessment of acute oral toxicity of quercetin loaded alginate/chitosan nanoparticles: in vivo study T Nalini, S Khaleel Basha, A Mohamed Sadiq, V Sugantha Kumari Polymer Bulletin 80 (10), 10921-10937 , 2023 2023 Citations: 6
In vitro cytocompatibility evaluation of nanostarch reinforced polyaniline-polyvinyl alcohol conductive bionanocomposites for skin tissue engineering application D Switha, SK Basha, VS Kumari Journal of Umm Al-Qura University for Applied Sciences 9 (3), 252-259 , 2023 2023 Citations: 7
Fabrication and evaluation of nanoencapsulated quercetin for wound healing application T Nalini, S Khaleel Basha, A Mohamed Sadiq, V Sugantha Kumari Polymer bulletin 80 (1), 515-540 , 2023 2023 Citations: 45
Pectin/chitosan nanoparticle beads as potential carriers for quercetin release T Nalini, SK Basha, AM Sadiq, VS Kumari Materials Today Communications 33, 104172 , 2022 2022 Citations: 56
In Vitro Studies of Chitosan/PVA/Methylcellulose—Silver Nanocomposites Scaffolds Using L929 Fibroblast Cells K Kanimozhi, VS Kumari, SK Basha, K Kaviyarasu Nanomaterials for Energy Conversion, Biomedical and Environmental … , 2022 2022 Citations: 2
In Vitro Degradation Behaviour of Chitosan-Based Blends by ATR-FTIR for Tissue Engineering Scaffolds: An Indirect Bioactivity Assay K Kanimozhi, VS Kumari, SK Basha, K Kaviyarasu Nanomaterials for Energy Conversion, Biomedical and Environmental … , 2022 2022
In vitro cytocompatibility assessment and antibacterial effects of quercetin encapsulated alginate/chitosan nanoparticle T Nalini, SK Basha, AM Sadiq, VS Kumari International Journal of Biological Macromolecules 219, 304-311 , 2022 2022 Citations: 64
A novel, biocompatible nanostarch incorporated Polyaniline-Polyvinyl alcohol-Nanostarch hybrid scaffold for tissue engineering applications D Switha, SK Basha, VS Kumari European Polymer Journal 178, 111448 , 2022 2022 Citations: 13
BIOPOLYMERIC NANOCOMPOSITE SCAFFOLDS FOR NERVE TISSUE ENGINEERING APPLICATIONS: A REVIEW D Switha, SK Basha, VS Kumari Journal of Applied Chemical Science International 13 (4), 25-50 , 2022 2022
Nano zinc oxide and nano bioactive glass reinforced chitosan/poly (vinyl alcohol) scaffolds for bone tissue engineering application PN Christy, SK Basha, VS Kumari Materials Today Communications 31, 103429 , 2022 2022 Citations: 58
Enhancement of performance and reduction in emissions of hydrogen supplemented Aleurites fordii biodiesel blend operated diesel engine PS Ranjit, SK Basha, SS Bhurat, A Thakur, AV Babu, GS Mahesh, ... International Journal of Vehicle Structures and Systems 14 (2), 174-178 , 2022 2022 Citations: 38
Development of nanoemulsion of Alginate/Aloe vera for oral delivery of insulin SK Basha, MS Muzammil, R Dhandayuthabani, VS Kumari Materials Today: Proceedings 36, 357-363 , 2021 2021 Citations: 31
Solid lipid nanoparticles for oral drug delivery SK Basha, R Dhandayuthabani, MS Muzammil, VS Kumari Materials today: proceedings 36, 313-324 , 2021 2021 Citations: 107
Polysaccharides as excipient in drug delivery system SK Basha, MS Muzammil, R Dhandayuthabani, VS Kumari Materials today: proceedings 36, 280-289 , 2021 2021 Citations: 20
Nanoemulsion as oral drug delivery-a review KB Sabjan, SM Munawar, D Rajendiran, SK Vinoji, K Kasinathan Current Drug Research Reviews Formerly: Current Drug Abuse Reviews 12 (1), 4-15 , 2020 2020 Citations: 70
Biopolymeric nanocomposite scaffolds for bone tissue engineering applications–A review PN Christy, SK Basha, VS Kumari, AKH Bashir, M Maaza, K Kaviyarasu, ... Journal of drug delivery science and technology 55, 101452 , 2020 2020 Citations: 208
MOST CITED SCHOLAR PUBLICATIONS
Silver, gold and bimetallic nanoparticles production using single-cell protein ( Spirulina platensis ) Geitler K Govindaraju, SK Basha, VG Kumar, G Singaravelu Journal of Materials Science 43 (15), 5115-5122 , 2008 2008 Citations: 523
Synthesis and characterization of chitosan-PVP-nanocellulose composites for in-vitro wound dressing application R Poonguzhali, SK Basha, VS Kumari International journal of biological macromolecules 105, 111-120 , 2017 2017 Citations: 217
Biopolymeric nanocomposite scaffolds for bone tissue engineering applications–A review PN Christy, SK Basha, VS Kumari, AKH Bashir, M Maaza, K Kaviyarasu, ... Journal of drug delivery science and technology 55, 101452 , 2020 2020 Citations: 208
Processing and characterization of chitosan/PVA and methylcellulose porous scaffolds for tissue engineering K Kanimozhi, SK Basha, VS Kumari Materials Science and Engineering: C 61, 484-491 , 2016 2016 Citations: 206
Development and characterization of alginate/chitosan nanoparticulate system for hydrophobic drug encapsulation T Nalini, SK Basha, AMM Sadiq, VS Kumari, K Kaviyarasu Journal of Drug Delivery Science and Technology 52, 65-72 , 2019 2019 Citations: 166
Novel asymmetric chitosan/PVP/nanocellulose wound dressing: In vitro and in vivo evaluation R Poonguzhali, SK Basha, VS Kumari International journal of biological macromolecules 112, 1300-1309 , 2018 2018 Citations: 115
Solid lipid nanoparticles for oral drug delivery SK Basha, R Dhandayuthabani, MS Muzammil, VS Kumari Materials today: proceedings 36, 313-324 , 2021 2021 Citations: 107
Phytochemical mediated gold nanoparticles and their PTP 1B inhibitory activity SK Basha, K Govindaraju, R Manikandan, JS Ahn, EY Bae, G Singaravelu Colloids and Surfaces B: Biointerfaces 75 (2), 405-409 , 2010 2010 Citations: 94
In vitro cytocompatibility of chitosan/PVA/methylcellulose–Nanocellulose nanocomposites scaffolds using L929 fibroblast cells K Kanimozhi, SK Basha, VS Kumari, K Kaviyarasu, M Maaza Applied Surface Science 449, 574-583 , 2018 2018 Citations: 88
Fabrication of asymmetric nanostarch reinforced Chitosan/PVP membrane and its evaluation as an antibacterial patch for in vivo wound healing application R Poonguzhali, SK Basha, VS Kumari International journal of biological macromolecules 114, 204-213 , 2018 2018 Citations: 77
Development of biomimetic hybrid porous scaffold of chitosan/polyvinyl alcohol/carboxymethyl cellulose by freeze-dried and salt leached technique K Kanimozhi, SK Basha, VS Kumari, K Kaviyarasu Journal of nanoscience and nanotechnology 18 (7), 4916-4922 , 2018 2018 Citations: 76
Nanoemulsion as oral drug delivery-a review KB Sabjan, SM Munawar, D Rajendiran, SK Vinoji, K Kasinathan Current Drug Research Reviews Formerly: Current Drug Abuse Reviews 12 (1), 4-15 , 2020 2020 Citations: 70
In vitro antidiabetic activity of Psidium guajava leaves extracts SK Basha, VS Kumari Asian Pacific Journal of Tropical Disease 2, S98-S100 , 2012 2012 Citations: 67
In vitro cytocompatibility assessment and antibacterial effects of quercetin encapsulated alginate/chitosan nanoparticle T Nalini, SK Basha, AM Sadiq, VS Kumari International Journal of Biological Macromolecules 219, 304-311 , 2022 2022 Citations: 64
Nano zinc oxide and nano bioactive glass reinforced chitosan/poly (vinyl alcohol) scaffolds for bone tissue engineering application PN Christy, SK Basha, VS Kumari Materials Today Communications 31, 103429 , 2022 2022 Citations: 58
Ammonia sensor and antibacterial activities of green zinc oxide nanoparticles SK Basha, KV Lakshmi, VS Kumari Sensing and Bio-Sensing Research 10, 34-40 , 2016 2016 Citations: 57
Pectin/chitosan nanoparticle beads as potential carriers for quercetin release T Nalini, SK Basha, AM Sadiq, VS Kumari Materials Today Communications 33, 104172 , 2022 2022 Citations: 56
Synthesis of alginate/nanocellulose bionanocomposite for in vitro delivery of ampicillin R Poonguzhali, S Khaleel Basha, V Sugantha Kumari Polymer Bulletin 75 (9), 4165-4173 , 2018 2018 Citations: 47
Fabrication and evaluation of nanoencapsulated quercetin for wound healing application T Nalini, S Khaleel Basha, A Mohamed Sadiq, V Sugantha Kumari Polymer bulletin 80 (1), 515-540 , 2023 2023 Citations: 45
Nanostarch reinforced with chitosan/poly (vinyl pyrrolidone) blend for in vitro wound healing application R Poonguzhali, SK Basha, VS Kumari Polymer-Plastics Technology and Engineering 57 (14), 1400-1410 , 2018 2018 Citations: 40
