Clinical Biochemistry, Biochemistry, Microbiology (medical), Immunology and Allergy
57
Scopus Publications
1101
Scholar Citations
18
Scholar h-index
32
Scholar i10-index
Scopus Publications
Is creatine kinase a valid aid in early cardiac muscle damage detection during treatment for childhood acute lymphoblastic leukemia? A case report Grazia Fazio, Jari Intra, Orsola Montini, Laura Rachele Bettini, Giacomo Gotti, Alessandra Sala, Silvia Bungaro, Giovanni Cazzaniga, Carmelo Rizzari, Adriana Balduzzi, Marco Casati Frontiers in Oncology, 2026 Creatine kinase (CK) is an enzyme that plays a pivotal role in various physiological processes, including metabolism and muscle function. This enzyme is found in high concentrations in skeletal muscle and the myocardium, with lower levels present in the brain. Increases in CK values have been observed in muscle damage and neuromuscular disorders. The potential for cardiotoxicity resulting from the administration of chemotherapeutic agents has been identified in subjects affected by hematological or solid tumors. In the present work, we describe the case story of a child diagnosed with acute lymphoblastic leukemia who exhibited two episodes of asymptomatic, markedly elevated CK values, identified during chemotherapy treatment. Our aim was to investigate the potential of CK as a biomarker for the early detection of cardiac muscle damage during therapy.
Cefepime and New Cefepime/Beta-Lactamase Inhibitor Combination for the Treatment of Gram-Negative Bacteria: Chemical Structure and Mechanism of Action, Microbiological Target, Clinical Use and PK/PD Characteristics Davide Carcione, Gioconda Brigante, Antonella Carducci, Jari Intra, Simone Ambretti, Floriana Campanile, Gabriele Arcari, Nicasio Mancini, Dario Cattaneo, Floriana Gona, Mariagrazia Perilli, Alessandra Piccirilli, Nicholas Geremia, Verena Zerbato, Stefano Di Bella, Giovanna Maria Nicolò, Luigi Principe Pharmaceuticals, 2026 The global spread of multidrug-resistant (MDR) Gram-negative bacteria, particularly extended-spectrum β-lactamase (ESBL)- and carbapenemase-producing Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter baumannii, presents a significant public health challenge by limiting effective antimicrobial treatment options. Cefepime, a fourth-generation cephalosporin with broad-spectrum activity, is increasingly compromised by β-lactamase production, efflux pumps, and porin loss. In response, novel cefepime-based β-lactam/β-lactamase inhibitor (BL/BLI) combinations have been developed to overcome these resistance mechanisms. This review examines preclinical and clinical studies on cefepime-based BL/BLI combinations, specifically cefepime/enmetazobactam, cefepime/taniborbactam, cefepime/zidebactam, and cefepime/nacubactam, as found in the PubMed database. Key findings include the restoration of activity against class A ESBLs with cefepime/enmetazobactam, while cefepime/taniborbactam and cefepime/zidebactam show broader inhibition of serine β-lactamases and selected metallo-β-lactamases. Additionally, zidebactam and nacubactam target penicillin-binding protein 2, enhancing bactericidal potency. Preclinical and early-phase clinical trial data indicate potent in vitro activity and favorable pharmacokinetic/pharmacodynamic (PK/PD) profiles. Specifically, the combination of cefepime with enmetazobactam has demonstrated an optimal Cmax/MIC ratio of 8–10, supporting its efficacy in treating MDR Gram-negative infections. Phase III studies are ongoing to confirm efficacy in complicated infections. Cefepime-based BL/BLI combinations are emerging as promising carbapenem-sparing agents, offering broad-spectrum activity, dual mechanisms of action, and encouraging clinical outcomes. These findings support their inclusion in antimicrobial stewardship strategies aimed at mitigating resistance.
Pain distribution in primary care patients affected by femoroacetabular impingement Roberto Centemeri, Michele Augusto Riva, Michael Belingheri, Maria Emilia Paladino, Marco Italo D'Orso, Jari Intra Journal of Orthopaedic Reports, 2025 Femoroacetabular impingement (FAI) is a well-known cause of hip pain deter-mined by morphological abnormalities between the femoral neck and the acetabular rim. In this work, we studied the pain location and distribution in subjects affected by FAI, in order to evaluate and identify the most common anatomical areas associated to this pathology. Fifty-two subjects, 29 females and 23 males, with an average age of 42 ± 13 years with clinical and radio-graphic confirmed FAI, were enrolled. Twenty-eight patients without signs of hip impingements were used as control group. The most frequent body areas where the pain was felt were lumbar-pelvic (41 %), knee (16 %), groin (14 %), and cervical shoulder region (12 %). Analyzing the data obtained among the two genders, the prevalence of pain in lumbar-pelvic region was observed both in males and females. Moreover, the males aged older than 40 years predominantly reported pain in lumbar-pelvic region, while females presented a higher variability in pain distribution, although pain in cervical-shoulder region was the most common. Collectively, a heterogeneous pain location and distribution was observed, and no specific was reported as distinctive of this pathology. However, the correlation between the pain location and the radiological findings could be useful to clinicians to implement early optimal conservative treatments and work/sport restrictions in order to monitor the evolution of pathology and improve patient's outcomes before a possible surgical treatment.
Lean approach applied to the blood gas system in point-of-care testing (POCT): The IRCCS San Gerardo dei Tintori experience Violetta Romano, Jari Intra, Nicoletta Novati, Francesca Basta, Marco Casati International Journal of Healthcare Management, 2025 Costs of medical care have increased worldwide, which may be due to unnecessary operational inefficiency. Different approaches exist to enhance procedural processes, and the Lean concept is used to improve quality and performance by systematically eliminating waste. In this study, Lean methodology with the four-stage Deming cycle (Plan, Do, Check, and Act) was applied to the point-of-care testing (POCT) system of the IRCCS San Gerardo dei Tintori. Starting from the evaluation of the current strategies used in the clinical laboratory, our goal was to facilitate workflow standardization, increase the efficiency, appropriateness, and quality standards in the execution of blood gas analysis in POCT, and to plan improvements, staff satisfaction, and safety. Six qualitative key process indicators, such as workflow, work area management, visual checks, reagents and supplies inventory, sample traceability, and work standardization, were used to investigate problems and identify solutions. The adoption of cutting-edge technologies, the training of personnel on the best pre-analytical practices, the standardization of cleaning procedures, the distribution of easy check workflow charts, and standardized material request documents reduced manual operations from 70 to 40% and patient identification errors of 10x. This approach created a diffuse collaborative culture and improved standardization of processes and safety.
A subanalysis of Clostridium perfringens bloodstream infections from a 5-year retrospective nationwide survey (ITANAEROBY) Nicholas Geremia, Gianfranco Sanson, Luigi Principe, Roberta Maria Antonello, Verena Zerbato, Roberto Luzzati, Alberto Enrico Maraolo, Daniele Roberto Giacobbe, Chiara Sepulcri, Simone Ambretti, Richard Aschbacher, Laura Bartolini, Mariano Bernardo, Alessandra Bielli, Marina Busetti, Davide Carcione, Giulio Camarlinghi, Edoardo Carretto, Tiziana Cassetti, Chiara Chilleri, Francesco Giuseppe De Rosa, Saveria Dodaro, Raffaele Gargiulo, Francesca Greco, Anna Knezevich, Jari Intra, Tommaso Lupia, Erika Concialdi, Gabriele Bianco, Francesco Luzzaro, Carola Mauri, Gianluca Morroni, Adriana Mosca, Elisabetta Pagani, Eva Maria Parisio, Claudio Ucciferri, Chiara Vismara, Stefano Di Bella Anaerobe, 2024
The Clinical Challenge of Identifying Postural Changes Associated with Musculoskeletal Disorders in a Population of Adolescents: The Evaluation of a Diagnostic Approach Roberto Centemeri, Michele Augusto Riva, Michael Belingheri, Maria Emilia Paladino, Marco Italo D’Orso, Jari Intra Biomedicines, 2024 Background/Objectives: Inappropriate posture, overweight, and physical inactivity are common causes of pathologies on muscles, ligaments, joints, and bone structures, which could negatively impact the quality of present and future life. The challenge of this work was to develop a diagnostic approach to identify the causes of musculoskeletal disorders in an adolescent population in order to implement preventive procedures. Methods: A total of 147 subjects aged between 14 and 18 years who were affected by musculoskeletal disorders and who accessed the Clinical Posturology unit of the IRCCS San Gerardo hospital, Monza, Italy, from 2015 to 2023, were enrolled. The clinical evaluation of each subject included a posturology visit, a physical examination, instrumental devices, such as stabilometric platform, gait analysis, MuscleLab, and imaging tests, such as Radiographic and Magnetic resonance, and a final diagnosis. Results: Ninety-eight (66.6%) subjects reported pain at the lumbar spine (33.3%), followed by knee/lower limb (22.4%), cervical spine (13%), and dorsal spine (12.3%). Imaging diagnostics underlined alterations in the musculoskeletal components, bone dimorphism, and asymmetry of the skeleton in 68% of cases. Thirty-one (21%) subjects received a diagnosis of postural dysfunction, seventy-two (49%) received a diagnosis of somatic dysfunction, and ten (7%) received a diagnosis of both postural and somatic dysfunctions. Conclusions: Our work highlighted that the three instrumental devices used allowed us to detect somatic and postural functional changes that cause musculoskeletal pathologies in adolescents.
Characteristics of 15 Subjects Affected by IgD Multiple Myeloma and the Key Role of the Laboratory in Diagnosis: A Retrospective Study Report and Literature Review Jari Intra, Sara Pezzatti, Rinaldo Brivio, Monica Carpenedo, Rita Romano, Nadia Spinoni, Marco Casati International Journal of Translational Medicine, 2024 Immunoglobulin D (IgD) myeloma represents an uncommon subtype of multiple myeloma (MM), accounting for 1–2% of cases. Subjects affected by IgD MM have been demonstrated to have an inferior outcome and survival compared to those with other MM subtypes. A retrospective study was conducted on 15 patients (9 males and 6 females) diagnosed from 2008 to 2022 with IgD MM, in order to investigate the clinical and biochemical features at the moment of diagnosis, cytogenetic alterations, and survival times. The median age was 69 years, and higher frequencies of bone lesions, renal impairments, Bence–Jones proteinuria, and increased serum LDH were observed. Serum calcium levels were in the reference ranges. In the assessment of protein electrophoresis patterns, nine patients had a serum monoclonal protein that was not detectable. A cytogenetic analysis via fluorescence in situ demonstrated that the most common abnormalities were the deletion of 13q and IGH rearrangements. Patients treated with new chemotherapeutic drugs (immunomodulators, proteasome inhibitors), with or without autologous stem cell transplantation presented a higher median survival. The fundamental role of the laboratory in monoclonal IgD detection and the monitoring and studying of IgD MM cases enhances the knowledge of this disease, thus improving patient outcomes.
The Role of Serum IgG Precipitins against Six Typical Organic Antigens Involved in Hypersensitivity Pneumonitis: A 10-Year Retrospective Study of a Referral Interstitial Lung Disease Centre Jari Intra, Alice Biffi, Francesca Basta, Cristina Delfini, Nicoletta Novati, Elisa Zucchetti, Fabrizio Luppi, Marco Casati International Journal of Translational Medicine, 2024 Hypersensitivity pneumonitis (HP) represents the third common interstitial lung disease caused by an exaggerated immune response following the inhalation of organic and/or chemical environmental antigens. The aim of this study was to determine the cut-off values of specific IgG antibodies (named precipitins) and their association with clinical data in the diagnosis of HP. In this 10-year retrospective study, the IgG concentrations against six antigens, Penicillium chrysogenum/notatum, Aspergillus fumigatus, Alternaria alternata, Aspergillus niger, Micropolyspora faeni, and pigeon droppings, were retrieved. The controlled group was made of 1516 healthy subjects without diagnosis of lung pathologies, while the case group consisted of 54 individuals affected by HP. Considering all six IgG antibodies together and the 97.5% percentiles determined in the control group, 30 of 54 subjects (56%) had one or more positive precipitins. In these patients, the major frequencies found were IgG antibodies against pigeon droppings, followed by Penicillium chrysogenum/notatum and Aspergillus niger. Although the sensitivity of serum precipitins depends on the population enrolled and the method used, the cut-off values determined in this study can be a valuable tool for clinicians in the diagnosis of HP, in eliminating the antigens responsible from the environment, and in establishing more specific IgG panels.
Surveillance of Bacterial Meningitis in the Italian Hospital of Desio: A Twenty-Year Retrospective Study Jari Intra, Davide Carcione, Roberta Maria Sala, Claudia Siracusa, Paolo Brambilla, Valerio Leoni Applied Microbiology, 2024 Bacterial meningitis is a severe infection with a high fatality rate, and affects children in particular. Three vaccines against the most common bacterial causatives of meningitis, Haemophilus influenzae type b, Streptococcus pneumoniae, and Neisseria meningitides, exist. Monitoring the type and incidence of bacterial meningitis is important for making future prevention and control plans. In this study, we retrospectively analyzed data regarding bacterial meningitis recovered in the Italian Hospital of Desio from 2000 to 2019. Samples from a total of 128 patients were included. Streptococcus pneumoniae was the most common microorganism, isolated in 45 cases, followed by Neisseria meningitidis (14), Listeria monocytogenes (8), Streptococcus agalactiae (group B) (4), and Haemophilus influenzae type b (2). The implementation of vaccination schedules decreased the number of bacterial meningitis cases caused by H. influenzae type b, S. pneumoniae, and N. meningitidis. Considering the bacterial meningitis cases in subjects aged 0–12 years, no H. influenzae type b strain was isolated, five cases of N. meningitidis were identified before the introduction of vaccination, and seven S. pneumoniae strains were isolated before the introduction of the PCV13 vaccination. Surveillance studies allowed us to monitor changes in bacteria distribution and to guide vaccination strategies.
Is creatine kinase a valid aid in early cardiac muscle damage detection during treatment for childhood acute lymphoblastic leukemia? A case report G Fazio, J Intra, O Montini, LR Bettini, G Gotti, A Sala, S Bungaro, ... Frontiers in Oncology 16, 1668068 , 2026 2026
Familial pseudohyperkalemia: a suspected case and its diagnostic implications in clinical laboratory medicine B JANCE, S IPPOLITO, A CAPPELLANI, C FANIA, J INTRA, ... Biochimica Clinica 17 , 2026 2026
Cefepime and New Cefepime/Beta-Lactamase Inhibitor Combination for the Treatment of Gram-Negative Bacteria: Chemical Structure and Mechanism of Action, Microbiological Target … D Carcione, G Brigante, A Carducci, J Intra, S Ambretti, F Campanile, ... Pharmaceuticals 19 (2), 283 , 2026 2026 Citations: 1
Pilot study on Exoskeleton Biomechanics in a Young Population: Variations in Frequency, Speed, Force, and Power during a Physical movement R Centemeri, M Riva, J Mennucci, S Pollastri, M Belingheri, M Paladino, ... European Journal of Biology and Biotechnology 7 (1), 9-13 , 2026 2026
The Stability of Urine chemistry strip parameters Stored in BD Vacutainer® UAP Preservative Tubes I Jari, I Pietro, B Francesca, F Lidia, M Davide, Z Elisa, Z Laura, C Marco WebLog Journal of Analytical and Pharmaceutical Chemistry , 2025 2025
Pain distribution in primary care patients affected by femoroacetabular impingement R Centemeri, MA Riva, M Belingheri, ME Paladino, MI D'Orso, J Intra Journal of Orthopaedic Reports 4 (4), 100479 , 2025 2025
Lean approach applied to the blood gas system in point-of-care testing (POCT): The IRCCS San Gerardo dei Tintori experience V Romano, J Intra, N Novati, F Basta, M Casati International Journal of Healthcare Management 18 (4), 708-714 , 2025 2025 Citations: 1
Treatment of Gonalgia Predominantly of Degenerative Origin with Manual Therapy and Myofibrolysis: a case series report S Orzes, R Tendi, R Centemeri, J Intra International Journal of Recent Advances in Multidisciplinary Research , 2025 2025
Susceptibility patterns of Streptococcus pyogenes isolated in the Italian Hospital of Desio: a 20-year (2000-2019) retrospective study. J Intra, D Carcione, RM Sala, C Siracusa, P Brambilla, V Leoni Microbiologia Medica 40 (2), 1 , 2025 2025
A subanalysis of Clostridium perfringens bloodstream infections from a 5-year retrospective nationwide survey (ITANAEROBY) N Geremia, G Sanson, L Principe, RM Antonello, V Zerbato, R Luzzati, ... Anaerobe 90, 102901 , 2024 2024 Citations: 9
The clinical challenge of identifying postural changes associated with musculoskeletal disorders in a population of adolescents: the evaluation of a diagnostic approach R Centemeri, MA Riva, M Belingheri, ME Paladino, MI D’Orso, J Intra Biomedicines 12 (10), 2168 , 2024 2024 Citations: 4
Characteristics of 15 subjects affected by IGD multiple myeloma and the key role of the laboratory in diagnosis: a retrospective study report and literature review J Intra, S Pezzatti, R Brivio, M Carpenedo, R Romano, N Spinoni, ... International Journal of Translational Medicine 4 (3), 498-504 , 2024 2024 Citations: 3
The role of serum IgG precipitins against six typical organic antigens involved in hypersensitivity pneumonitis: a 10-year retrospective study of a referral interstitial lung … J Intra, A Biffi, F Basta, C Delfini, N Novati, E Zucchetti, F Luppi, M Casati International Journal of Translational Medicine 4 (2), 381-386 , 2024 2024 Citations: 6
Surveillance of Bacterial Meningitis in the Italian Hospital of Desio: A Twenty-Year Retrospective Study J Intra, D Carcione, RM Sala, C Siracusa, P Brambilla, V Leoni Applied Microbiology 4 (1), 481-485 , 2024 2024
Elevated urine norepinephrine levels and alcohol use: A relationship that should be not neglected J Intra, S Ippolito, F Lorenzini, A Mauro, MC Mazzitello, S Melzi, ... Clinical biochemistry 123, 110704 , 2024 2024
The Evaluation of the Balance Test and MuscleLab Test for the Early Detection of Femoroacetabular Impingement R Centemeri, MA Riva, M Belingheri, ME Paladino, MI D’Orso, J Intra Journal of Functional Morphology and Kinesiology 8 (4), 159 , 2023 2023 Citations: 2
New antimicrobials for gram-positive sustained infections: a comprehensive guide for clinicians D Carcione, J Intra, L Andriani, F Campanile, F Gona, S Carletti, ... Pharmaceuticals 16 (9), 1304 , 2023 2023 Citations: 19
The diagnostic performances of the Atellica® 1500 automated urinalysis system for ruling out bacterial urinary tract infection P Iezzi, F Cappellini, J Intra, S Carnicelli, L Fossati, F Basta, E Zucchetti, ... Clinica Chimica Acta 548, 117494 , 2023 2023 Citations: 6
Antimicrobial Resistance Patterns of Enterobacter cloacae and Klebsiella aerogenes Strains Isolated from Clinical Specimens: A Twenty-Year Surveillance Study J Intra, D Carcione, RM Sala, C Siracusa, P Brambilla, V Leoni Antibiotics 12 (4), 775 , 2023 2023 Citations: 55
Lombalgia e patologie emergenti: esperienza in operatori sanitari con conflitto femoro acetabolare FAI R Centemeri, M D’Orso, M Belingheri, M Paladino, J Intra, M Riva GIORNALE ITALIANO DI MEDICINA DEL LAVORO ED ERGONOMIA 45, 169-169 , 2023 2023
MOST CITED SCHOLAR PUBLICATIONS
Old and new beta-lactamase inhibitors: molecular structure, mechanism of action, and clinical use D Carcione, C Siracusa, A Sulejmani, V Leoni, J Intra Antibiotics 10 (8), 995 , 2021 2021 Citations: 150
Phylogenetic analyses suggest multiple changes of substrate specificity within the glycosyl hydrolase 20 family J Intra, G Pavesi, DS Horner BMC Evolutionary Biology 8 (1), 214 , 2008 2008 Citations: 74
Identification and expression analysis of Drosophila melanogaster genes encoding β-hexosaminidases of the sperm plasma membrane F Cattaneo, ME Pasini, J Intra, M Matsumoto, F Briani, M Hoshi, ME Perotti Glycobiology 16 (9), 786-800 , 2006 2006 Citations: 70
Comparative and phylogenetic analysis of α-l-fucosidase genes J Intra, ME Perotti, G Pavesi, D Horner Gene 392 (1-2), 34-46 , 2007 2007 Citations: 69
An α‐ L ‐fucosidase potentially involved in fertilization is present on Drosophila spermatozoa surface J Intra, F Cenni, ME Perotti Molecular reproduction and development 73 (9), 1149-1158 , 2006 2006 Citations: 67
Antimicrobial Resistance Patterns of Enterobacter cloacae and Klebsiella aerogenes Strains Isolated from Clinical Specimens: A Twenty-Year Surveillance Study J Intra, D Carcione, RM Sala, C Siracusa, P Brambilla, V Leoni Antibiotics 12 (4), 775 , 2023 2023 Citations: 55
Bacterial and fungal colonization of the respiratory tract in COVID-19 patients should not be neglected J Intra, C Sarto, E Beck, N Tiberti, V Leoni, P Brambilla American journal of infection control 48 (9), 1130 , 2020 2020 Citations: 46
Anaerobic bloodstream infections in Italy (ITANAEROBY): A 5-year retrospective nationwide survey S Di Bella, RM Antonello, G Sanson, AE Maraolo, DR Giacobbe, ... Anaerobe 75, 102583 , 2022 2022 Citations: 38
Prevalence and species distribution of microorganisms isolated among non-pregnant women affected by vulvovaginal candidiasis: A retrospective study over a 20 year-period J Intra, MR Sala, P Brambilla, D Carcione, V Leoni Journal of Medical Mycology 32 (3), 101278 , 2022 2022 Citations: 33
Antimicrobial Resistance Trends of Escherichia coli Isolates from Outpatient and Inpatient Urinary Infections over a 20-Year Period A Milano, A Sulejmani, J Intra, MR Sala, V Leoni, D Carcione Microbial Drug Resistance 28 (1), 63-72 , 2022 2022 Citations: 28
Glycosylated hemoglobin in subjects affected by iron-deficiency anemia J Kim, HS Chung, MK Choi, YK Roh, HJ Yoo, JH Park, DS Kim, JM Yu, ... Diabetes & Metabolism Journal 43 (4), 539-544 , 2019 2019 Citations: 28
Interspecific analysis of the glycosidases of the sperm plasma membrane in Drosophila J Intra, F Cenni, G Pavesi, M Pasini, ME Perotti Molecular Reproduction and Development: Incorporating Gamete Research 76 (1 … , 2009 2009 Citations: 27
Detection of intestinal parasites by use of the cuvette-based automated microscopy analyser sediMAX® J Intra, E Taverna, MR Sala, R Falbo, F Cappellini, P Brambilla Clinical Microbiology and Infection 22 (3), 279-284 , 2016 2016 Citations: 25
In Vitro Activity of Antifungal Drugs Against Trichophyton rubrum and Trichophyton mentagrophytes spp. by E-Test Method and Non-supplemented Mueller–Hinton … J Intra, C Sarto, S Mazzola, C Fania, N Tiberti, P Brambilla Mycopathologia 184 (4), 517-523 , 2019 2019 Citations: 24
Hemolysis and blood gas analysis: it’s time for a change! M Casati, J Intra, W Rossi, C Giacobone, R Brivio Scandinavian Journal of Clinical and Laboratory Investigation 82 (2), 138-142 , 2022 2022 Citations: 23
Drosophila sperm surface alpha-L-fucosidase interacts with the egg coats through its core fucose residues J Intra, V Concetta, ME Perotti, ME Pasini Insect biochemistry and molecular biology 63, 133-143 , 2015 2015 Citations: 20
New antimicrobials for gram-positive sustained infections: a comprehensive guide for clinicians D Carcione, J Intra, L Andriani, F Campanile, F Gona, S Carletti, ... Pharmaceuticals 16 (9), 1304 , 2023 2023 Citations: 19
Genus‐level identification of dermatophytes by MALDI‐TOF MS after 2 days of colony growth J Intra, C Sarto, N Tiberti, S Besana, C Savarino, P Brambilla Letters in applied microbiology 67 (2), 136-143 , 2018 2018 Citations: 19
The importance of considering the neglected intestinal protozoan parasite Dientamoeba fragilis J Intra, C Sarto, S Besana, N Tiberti, P Brambilla Journal of Medical Microbiology 68 (6), 890-892 , 2019 2019 Citations: 18
Baseline characteristics of COVID-19 Italian patients admitted to Desio Hospital, Lombardy: a retrospective study A Sulejmani, E Galimberti, C Giacobone, A Milano, E Scopetta, J Intra, ... Scandinavian journal of clinical and laboratory investigation 81 (1), 18-23 , 2021 2021 Citations: 17
