Enhancing antimicrobial properties of a resin-based material via incorporation of a powdered phytotherapeutic extract: an in vitro experimental study Rodolfo Xavier de Sousa-Lima, Maria Eduarda Lima do Nascimento Marinho, Janielly Cristina Costa da Silva, Moan Jéfter Fernandes Costa, Pedro Henrique Sette-de-Souza, et al. Restorative Dentistry and Endodontics, 2026 Objectives: This study aimed to evaluate the degree of conversion (DC), immediate enamel bond strength (IEBS), antimicrobial activity, and release of the active principle of a resin-based material (RBM) enriched with the powdered Schinopsis brasiliensis (Braúna) stem antibacterial extract.Methods: The RBM was enriched with 0, 1.25, 2.5, 5, 10, and 20 wt% powdered Braúna extract. The DC (<i>n</i> = 7) was assessed using micro-Raman spectroscopy. The IEBS (<i>n</i> = 7) was determined through the microshear test until failure, and failure modes were examined under a stereomicroscope. The antimicrobial activity (<i>n</i> = 15) was assessed by quantifying colony-forming units, and the release of the active principle was determined using ultra-high-performance liquid chromatography. One-way analysis of variance/Tukey and Kruskal-Wallis/Dunn tests were utilized to analyze the data (<i>p</i> < 0.05).Results: Materials with 10 wt% and 20 wt% extract showed the lowest DC statistically. However, for IEBS, there were no statistically significant differences among the different groups. All materials released the active principle, but only those with 20 wt% and 10 wt% extract could inhibit biofilm formation similarly to 0.12% chlorhexidine.Conclusions: Adding powdered Braúna extract between 10 wt% and 20 wt% is a promising alternative to provide an antimicrobial function to RBMs.
Nanostructured Clays Used as Carriers for Controlled Delivery of Antibacterial Compounds From Direct Restorative Dental Materials: A Scoping Review Bárbara Faria Sa de Barbosa, José Leôncio Ferreira Neto, Francisca Jennifer Duarte de Oliveira, Juliana Sales Osterno Leitão, Moan Jéfter Fernandes Costa, et al. Clinical and Experimental Dental Research, 2025 ObjectiveThrough a scoping review, this study meticulously mapped and characterized these nanostructured clays used to release antibacterial active compounds from direct restorative dental materials.Material and MethodsThe systematic approach involved searches in the PubMed/MEDLINE, Lilacs, Web of Science, Scopus, ScienceDirect, and Embase databases. Two independent and calibrated researchers (kappa: 0.94) performed all systematic steps according to the PRISMA guideline and the Joanna Briggs Institute Scoping Review Methodology Group (JBI) protocol. The reviewers developed a data extraction table to gather key information.ResultsA total of 782 articles were retrieved in the initial search using the specified strategies. After thoroughly reviewing the manuscripts, five were selected following the exclusion of duplicates and application of eligibility criteria. Montmorillonite and halloysite nanotubes emerged as the predominant nanostructured clay. Cetylpyridinium chloride was the most common active agent, notable for its antibacterial properties. Resin‐based composites were the most frequently studied direct restorative material for the prevention of recurrent caries.ConclusionAlthough the number of primary studies published in the literature was limited, montmorillonite and halloysite nanotubes appear to be promising nanocarriers for antibacterial active compounds in direct restorative dental materials.
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Efficacy of ibuprofen and codeine + paracetamol to reduce immediate bleaching sensitivity caused by in-office tooth bleaching: A randomized, controlled, double-blind clinical trial American Journal of Dentistry, 2018
Preheating of resin-based flowable materials in a microwave device: a promising approach to increasing hardness and softening resistance under cariogenic challenge. European Journal of Esthetic Dentistry Official Journal of the European Academy of Esthetic Dentistry, 2013
Can extended photoactivation time of resin-based fissure sealer materials improve ultimate tensile strength and decrease water sorption/solubility? European Journal of Dentistry, 2012
Progression of non-cavitated lesions in dentin through a nonsurgical approach: A preliminary 12-month clinical observation European Journal of Dentistry, 2012
Preliminary clinical reports of a novel night-guard tooth bleaching technique modified by casein phosphopeptide-amorphous calcium phosphate (CCP-ACP). European Journal of Esthetic Dentistry Official Journal of the European Academy of Esthetic Dentistry, 2011
Influence of the light curing tip distance and material opacity on selected physical properties of a pit and fissure sealant Pediatric Dentistry, 2011
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Efficacy of a pit and fissure sealant in arresting dentin non-cavitated caries: A 1-year follow-up, randomized, single-blind, controlled clinical trial American Journal of Dentistry, 2010
Hyposalivation and xerostomia: Prevalence and factors associated with cardiovascular diseases in the elderly Revista Multidisciplinar De Gerontologia, 2009
Clinical and microbiological characteristics in predicting dentine caries progression. Acta Odontologica Latinoamericana AOL, 2009
