Paola Cipriani
@univaq.it
University of L'Aquila
Scopus Publications
- Paraproteinemias in Sjögren disease: cryoglobulinemia and serum monoclonal gammopathy identify distinct clinical phenotypes and differential lymphoma susceptibility
Simone Longhino, Maria Teresa Rizzo, Valeria Manfrè, Giacomo Cafaro, Maria De Martino, Francesco Carubbi, Alessia Alunno, Nicoletta Del Papa, Paola Cipriani, Fabiola Atzeni, Onorina Berardicurti, Roberto Giacomelli, Serena Colafrancesco, Roberta Priori, Ludovica Manisera, Angelica Gattamelata, Serena Guiducci, Chiara Baldini, Elena Bartoloni, Luca Quartuccio
Seminars in Arthritis and Rheumatism, 2026
• Isolated detectable serum monoclonal gammopathy, cryoglobulinemia, and their coexistence delineate distinct phenotypic subsets in Sjögren disease (SjD). • Cryoglobulinemia is linked with a predominant vasculitic phenotype. • The combination of cryoglobulinemia and monoclonal gammopathy is linked with high lymphoproliferative activity and lymphoma susceptibility. • SjD patients with both serum detectable monoclonal gammopathy and cryoglobulinemia require careful monitoring due to increased lymphoma risk. Sjögren disease (SjD) is a systemic autoimmune disease characterized by increased risk of B-cell non-Hodgkin lymphoma. Although cryoglobulinemia and serum monoclonal component (MC) are well-recognized paraproteinemias in SjD, no large-scale study has directly compared their isolated and combined impact on phenotype and lymphoproliferative risk. A retrospective, multicenter, cross-sectional study was conducted within the Italian GRISS registry. Patients with SjD were stratified into four groups: isolated monoclonal gammopathy (MC-alone), isolated cryoglobulinemia (CRYO-alone), both (MC+CRYO), or neither (controls). Demographics, lymphoma history, ever-documented ClinESSDAI domains, and laboratory lymphoproliferative risk-related markers were analyzed. Primary and secondary outcomes assessed lymphoma diagnosis and the distribution of laboratory lymphoproliferative risk-related markers and ClinESSDAI domains across groups, with associations tested using logistic regression adjusted for confounders. 1202 SjD patients were enrolled: 58 (4.83%) in the MC-alone, 32 (2.66%) in the CRYO-alone, 35 (2.91%) in the MC+CRYO, and 1077 (89.60%) controls. Compared with controls, only the MC+CRYO group showed significant association with lymphoma (OR 6.30, 95%CI 2.66–14.92; p<0.001), while MC-alone and CRYO-alone were not associated. Cryoglobulinemia, alone or combined with MC, correlated with laboratory lymphoproliferative risk-related markers such as rheumatoid factor (p<0.001) and low C4 (p<0.001), and with ClinESSDAI vasculitic features (cutaneous [p<0.001], renal [p<0.05], PNS [p<0.001]). The MC+CRYO group additionally displayed a lymphoproliferative phenotype correlating with constitutional (p<0.05), glandular (p<0.05), hematological (p<0.001), and lymphadenopathy (p<0.001) domains. Cryoglobulinemia in SjD associates with vasculitic disease activity, whereas the coexistence of serum MC and cryoglobulins identifies a distinct, high-risk subset characterized by advanced B-cell expansion and increased lymphoma susceptibility. - Development and validation of clinical criteria for the definition of disease activity in adult-onset Still's disease: a cohort study
Piero Ruscitti, Tanja Stamm, Valentin Ritschl, Stéphane Mitrovic, Charlotte Girard-Guyonvarc'h, Fabiola Atzeni, Carina Bostrøm, Luca Cantarini, Francesco Caso, Paola Cipriani, Francesco Ciccia, Marco Gattorno, Giuliana Guggino, Francis Guillemin, Martin Krusche, Javier Llorca, Carlomaurizio Montecucco, Federico Perosa, Pierre Quartier, Angelo Ravelli, Nicolas Rosine, Maud Wieczorek, Tanita-Christina Wilhelmer, Miguel Ángel Gonzalez-Gay, Cem Gabay, Bruno Fautrel, Eugen Feist, Roberto Giacomelli, Claudia Kedor, Joachim Listing, Jan Zernicke, Anja Weiß, Frank Behrens, Norbert Blank, Joerg Christoph Henes, Joern Kekow, Andrea Rubbert-Roth, Hendrik Schulze-Koops, Eva Seipelt, Christof Specker
Lancet Rheumatology, 2026 - Real-world damage accrual in Sjögren's disease: a 5-year multicentre GIRRCS cohort analysis
Onorina Berardicurti, Annalisa Marino, Luca Navarini, Andrea Pilato, Marta Vomero, Letizia Pia Di Corcia, Irene Genovali, Damiano Currado, Lidia La Barbera, Rosaria Irace, Paola Conigliaro, Victoriya Pavlych, Valeria Guardo, Giorgio Carlino, Sara Ferrigno, Rosa Daniela Grembiale, Annamaria Iagnocco, Piero Ruscitti, Paola Cipriani, Maria Sole Chimenti, Francesco Ciccia, Giuliana Guggino, Roberto Giacomelli
Rmd Open, 2026
Introduction Primary Sjögren’s disease (SD) is a systemic autoimmune disorder causing glandular dysfunction, sicca symptoms and extraglandular manifestations, which impair quality of life. Data on early irreversible damage and its predictors remain limited. Methods We conducted a multicentre retrospective cohort study of 429 adult patients with SD from the Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale network with ≥1 year of follow-up. Baseline assessments included disease activity (European League Against Rheumatism (EULAR), Sjögren’s Syndrome Disease Activity Index (ESSDAI)), patient-reported symptoms (EULAR Sjögren’s Syndrome Patient Reported Index (ESSPRI)), C reactive protein (CRP), Schirmer’s test (ST) and autoantibody status. Irreversible damage was evaluated using the Sjögren’s Syndrome Damage Index (SSDI) across ocular, oral and systemic domains. Predictors of damage accrual were analysed using Cox proportional hazards models and Kaplan-Meier curves. Exploratory Least Absolute Shrinkage and Selection Operator (LASSO) and principal component analysis (PCA) analyses assessed domain-specific contributions and relationships between subjective and objective measures. Results At baseline, 48% of patients had SSDI≥1: ocular 25.4%, systemic 22.5% and oral 14.3%. After 5 years, 65% had cumulative damage: ocular 34.2%, oral 21.7% and systemic 40.8%. Higher baseline ESSDAI predicted damage across all domains. Elevated ESSPRI was associated with oral damage, while abnormal ST strongly predicted ocular damage. Anti-Ro/La antibodies, elevated CRP and recurrent oral infections were linked to higher domain-specific damage. LASSO analyses showed glandular, peripheral nervous system and pulmonary ESSDAI domains independently contributed to systemic damage. PCA confirmed that patient-reported symptoms and systemic activity represent complementary, independent dimensions. Conclusion Irreversible damage in SD occurs early, often present at diagnosis and affects multiple organ domains. Early identification of high-risk patients, based on clinical, serological and patient-reported measures, may enable timely interventions to prevent further damage, guide treatment and improve long-term outcomes. - Application of machine learning techniques to explore the occurrence of macrophage activation syndrome in Still’s disease: results from the GIRRCS AOSD Study Group and the AIDA Network Still’s Disease Registry
Piero Ruscitti, Francesco Masedu, Antonio Vitale, Valeria Caggiano, Ilenia Di Cola, Fabiola Atzeni, Jessica Sbalchiero, Giuseppe Lopalco, Florenzo Iannone, Maria Morrone, Daniela Iacono, Flavia Riccio, Mariachiara Visconti, Carla Gaggiano, Francesco Caso, Giacomo Emmi, Andrea Hinojosa-Azaola, Jiram Torres-Ruiz, Eduardo Martín-Nares, Giuliana Guggino, Lidia La Barbera, Ezgi D. Batu, Seza Ozen, Petros P. Sfikakis, Luca Navarini, Luisa Costa, Abdurrahman Tufan, Ibrahim Yahya Cakir, Federico Perosa, José Hernández-Rodríguez, Marcella Prete, Lorenzo Dagna, Corrado Campochiaro, Francesco Ursini, Paolo Sfriso, Sara Bindoli, Henrique A. Mayrink Giardini, Lampros Fotis, Katerina Kourtesi, Gaafar Ragab, Mahmoud Ghanema, Moustafa Ali Saad, Haner Direskeneli, Anastasios Karamanakos, Alessandro Conforti, Francesco La Torre, Micol Frassi, Marcello Govoni, Paola Parronchi, Piercarlo Sarzi-Puttini, Maria Cristina Maggio, Serena Bugatti, Ludovico De Stefano, Jacopo Pelizza, Elena Bartoloni, Donato Rigante, Annamaria Iagnocco, Ombretta Viapiana, Ewa Wiesik-Szewczyk, Joanna Makowska, Özgül Soysal Gündüz, Şükran Erten, Benson Ogunjimi, Gian Domenico Sebastiani, Emanuela Del Giudice, Edoardo Biancalana, Giovanni Conti, Ibrahim A. AlMaghlouth, Luciana Breda, Antonio Gidaro, Patrizia Barone, Alma Nunzia Olivieri, Francesco Carubbi, Amato De Paulis, Maria Sole Chimenti, Alberto Lo Gullo, Samar Tharwat, Maissa Thabet, Abdelhfeez Moshrif, Maria Alessio, Angela Mauro, Benoit Suzon, Valentina Pucino, Oksana Boyarchuk, Tetiana Kovalchuk, Cemal Bes, Rabia Deniz, Sulaiman M. Al-Mayouf, Paola Cipriani, Marco Valenti, Alberto Balistreri, Claudia Fabiani, Francesco Ciccia, Carlomaurizio Montecucco, Roberto Giacomelli, Bruno Frediani, Luca Cantarini
Frontiers in Immunology, 2026
Objectives This study aims to explore the application of machine learning techniques in assessing macrophage activation syndrome (MAS) in Still’s disease. Methods A multicenter, observational, prospective study was conducted, including patients with Still’s disease enrolled in the Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) AOSD Study Group and the AutoInflammatory Disease Alliance (AIDA) Network Still’s Disease Registry. Results A total of 737 patients (age: 35.5 ± 17.8, male sex: 44.7%) with Still’s disease were assessed; 11.4% were affected by MAS, and 3% had a poor prognosis. First, random forest imputation was applied to the original dataset. Subsequently, a machine-learning-driven assessment was developed to explore MAS occurrence. Collectively, regression models, an exploration decision tree, and a random forest were applied, suggesting the importance of ferritin, age, C-reactive protein (CRP), and systemic score. A logistic regression model accounting for data leakage concerns was then generated using these variables, and missing values were imputed using random forest imputation. This analysis supported the role of the selected variables, which were further combined across different clinical scenarios to estimate the probability of MAS. The highest risk of MAS was estimated for patients simultaneously characterized by age ≥ 45 years, ferritin ≥ 4,178.10 ng/mL, CRP ≥ 27.15 mg/L, and a systemic score ≥ 7, corresponding to a 34.7% probability of MAS, as well as for those characterized by ferritin ≥ 4,178.10 ng/mL, CRP ≥ 27.15 mg/L, and systemic score ≥ 7, corresponding to a 33.5% probability of MAS. Conclusions A machine-learning-driven prediction of MAS was explored in Still’s disease, highlighting the importance of age of onset, hyperferritinaemia, increased CRP, and multiorgan involvement. A combination of these features may suggest a clinician-friendly algorithm for stratifying the probability of MAS during Still’s disease. - Jurkat T-Cell Antigen-Independent Elimination of PMA-Activated Neuroblastoma Cells Is Triggered by CCL2/CCR2, Depends Upon Lipid Raft LFA1/ICAM1 Immune Synapses, Is Mediated by m-TRAIL and Is Augmented by the TrkAIII Oncoprotein
Maddalena Sbaffone, Ilaria Martelli, Paola Cipriani, Antonietta Rosella Farina, Lucia Annamaria Cappabianca, Andrew Reay Mackay
International Journal of Molecular Sciences, 2026
Advances in multimodal therapy for high-risk neuroblastomas (NBs) have plateaued, prompting therapeutic initiatives to harness the immune system. NBs, however, are immunologically “cold” and a significant challenge to immunotherapy. Here, in a Jurkat lymphocyte cytotoxicity model, we describe an antigen-independent, cell-mediated mechanism for eliminating NB cells, first detected in PMA-activated low pcDNA-SH-SY5Y and high TrkAIII-SH-SY5Y TrkAIII-expressing cells, which are resistant to Jurkat elimination under normal conditions. Characterization of this mechanism through live cell imaging, adhesion assays, RT-PCR, Western blotting and indirect IF, employing a variety of inhibitors, indicates that it initiates with PMA-induced NB cell CCL2 expression. This results in CCL2 promotion of Jurkat CCR2b expression, CCL2/CCR2b-mediated Jurkat LFA-1 activation and the formation of cytotoxic lipid-raft LFA1/ICAM-1 immune synapses, through which Jurkat m-TRAIL combines with PMA-enhanced NB cell DR5/TRAIL-R2 expression to induce NB cell apoptosis. This mechanism is enhanced by the NB-associated oncoprotein TrkAIII through Shp/Src-regulated c-FLIP sequester and is PD-L1/PD-1-independent and resistant to osteoprotegerin. It eliminates both non-MYCN-amplified (SH-SY5Y and SK-N-SH) and MYCN-amplified (SMS-KCNR) NB cells that exhibit PMA-inducible CCL2 expression but not MYCN-amplified NB cells (IMR-32 and NB-1) that exhibit CCL2 repression, and is offset by reciprocal NB cell-induced Fas-mediated Jurkat cell apoptosis. These findings form a solid foundation for further pre-clinical development aimed at identifying clinically relevant physiological immune cell equivalents and alternative PKC activators, with the ultimate goal of translating this mechanism into an effective immune-therapeutic approach for the treatment of high-risk non-immunogenic NBs, especially NBs that exhibit CCL2 and TrkAIII expression. - The evaluation of effectiveness of IL-17 and IL-23 inhibitors on nail and enthesis involvement in early psoriatic arthritis patients by high-frequency ultrasonography: a single-centre prospective proof-of-concept study
Piero Ruscitti, Camilla Gianneramo, Pierpaolo Palumbo, Manfredo Bruni, Martina Gentile, Sabrina Lanzi, Emanuele Vagnozzi, Alessia Loda, Lina Maria Magnanimi, Maria Concetta Fargnoli, Antonio Barile, Paola Cipriani, Maria Esposito
Radiologia Medica, 2025
Purpose To evaluate the effectiveness of IL-17 and IL-23 inhibitors in psoriatic nail and enthesis involvement by ultrasonography with the use of high-frequency probes (HFUS). To correlate the obtained HFUS findings with disease activity of patients with psoriatic arthritis (PsA). Material and Methods Consecutive early naïve patients with PsA underwent HFUS on nails and entheses before and after 24 weeks of treatment with IL-17 or IL-23 inhibitor. The Brown University Nail Enthesis Scale (BUNES), considering morphometry and Power Doppler (PD), and the Madrid Sonography Enthesitis Index (MASEI) score were used to evaluate these features. HFUS findings were correlated with the extension of the disease on skin by Psoriasis Area and Severity Index (PASI) and joints by Disease Activity Index for Psoriatic Arthritis (DAPSA). Results Twenty early naïve patients with PsA were treated for 24 weeks with an IL-17 or IL-23 inhibitor. A significant reduction of BUNES PD was observed considering the whole cohort of patients receiving these drugs (p = 0.044), whereas, despite a trend, no significant difference was reported comparing BUNES morphometry. The BUNES PD correlated with PASI (r = 0.466, p = 0.030) and with DAPSA (r = 0.444, p = 0.032), whereas BUNES morphometry did not. A significant reduction of MASEI was observed considering the whole assessed cohort of patients treated with these drugs (p = 0.045). The MASEI correlated with both PASI (r = 0.429, p = 0.037) and DAPSA (r = 0.499, p = 0.017). Conclusions This proof-of-concept study demonstrated that the assessment by HFUS may provide additional accurate information about the effectiveness of IL-17 and IL-23 inhibitors in psoriatic nail and enthesis involvement. - Clinical and serological differences of an Italian Sjögren’s disease cohort according to three geographic macro-area localisations
Fabiola Atzeni, Maria Letizia Currò, Roberto Dal Pozzolo, Giacomo Cafaro, Valeria Manfrè, Luca Quartuccio, Francesco Carubbi, Alessia Alunno, Nicoletta Del Papa, Paola Cipriani, Onorina Berardicurti, Roberta Priori, Angelica Gattamelata, Serena Guiducci, Elena Bartoloni
Clinical and Experimental Rheumatology, 2025
OBJECTIVES: The phenotype of Sjögren's disease (SjD) may be influenced by several variables. Among these, the role of patient geolocation has been poorly explored. The study compared epidemiologic, serologic, clinical features and comorbidities according to geographical origin in a large Italian multicentre SjD cohort. METHODS: This is a retrospective analysis of a multicentre SjD cohort (2016 ACR/EULAR criteria) consecutively included in the Italian SjD Study Group registry and grouped into three macrogeographic areas: North, Centre and South. Disease-specific epidemiologic, serologic, histologic and clinical variables were collected. Comorbidities, traditional cardiovascular (CV) risk factors and history of CV events were also recorded. All data were stratified by geographic area to assess regional differences. RESULTS: 1231 SjD patients, median 53 (42-63) years at diagnosis and 95% females, were included. No differences were observed in sex distribution or ethnicity among the three areas. Patients from the South had older age at diagnosis compared to the North (55 vs. 51 years, p=0.001) and Centre (55 vs. 51 years, p=0.002) and higher frequency of activity in the constitutional and articular but lower in biological domains (p<0.001 for all). Hypertension and hypercholesterolaemia were more prevalent in the Centre and obesity was more common in the South compared to the North (p<0.001). No significant differences were observed in other CV risk factors and CV events. CONCLUSIONS: This study provides the first evidence of geo-epidemiological differences among Italian SjD patients, highlighting how geographic origin is associated with disease phenotype and comorbidities. These regional disparities likely reflect environmental, socio-cultural and healthcare system-related factors, underscoring the need for personalised disease management strategies. - Type II diabetes in systemic sclerosis patients: insights from an observational, multicenter study of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale)
Vasiliki Liakouli, Giulio Forte, Piero Ruscitti, Luca Navarini, Francesca Bellisai, et al.
Arthritis Research and Therapy, 2025
OBJECTIVE: To assess the contribution of Systemic sclerosis (SSc)-specific features on type II diabetes mellitus (T2D) in a large cohort of Italian SSc patients. METHODS: A total of 613 SSc patients from 11 tertiary Rheumatology Units across Italy were included. All patients underwent full history taking, clinical examination, and relevant laboratory and radiological evaluations. Demographic, socioeconomic, and disease-specific factors were compared between SSc patients with and without T2D. RESULTS: The prevalence of T2D in the study cohort was 7.6%. SSc patients with T2D were significantly older (P < 0.007) and exhibited: higher prevalence of late-stage capillaroscopic pattern (P < 0.001), severe reduction in forced vital capacity (FVC < 50%; P < 0.000), moderate reduction in total lung capacity (TLC 50-69%; P < 0.011), electrocardiographic signs of right ventricular hypertrophy (P < 0.018), higher prevalence of pulmonary arterial hypertension (PAH) confirmed by right heart catheterization (RHC) (P < 0.037) and higher prevalence scleroderma renal crisis (SRC) (P < 0.001); elevated erythrocyte sedimentation rate (ESR) (P < 0.022), and ANA positivity. These patients more frequently assumed angiotensin-converting enzyme inhibitors (ACEi) (P < 0.005) when compared to their non-T2D counterparts, while the use of immunosuppressive therapies was similar between groups. Multivariate analysis identified older age, SRC, and reductions in both TLC and FVC as independent SSc-specific associated factors of T2D. CONCLUSION: Although the prevalence of T2D in SSc patients is lower than the global estimates reported by the International Federation of Diabetes (IFD), a distinct subgroup of SSc patients with T2D is characterized by unique disease manifestations and complications, including SRC and impaired lung function. These findings underscore the importance of tailored screening and management approaches to address the intersecting metabolic and vascular risks in this population. - Pain catastrophizing and its domains significantly impact rheumatoid arthritis disease activity
Damiano Currado, Lyubomyra Kun, Francesca Saracino, Leonardo Frascà, Francesca Trunfio, Onorina Berardicurti, Erika Corberi, Annalisa Marino, Andrea Pilato, Ludovica Lamberti, Marta Vadacca, Amelia Rigon, Luisa Arcarese, Piero Ruscitti, Ilenia Pantano, Marta Vomero, Viktoriya Pavlych, Claudio Di Vico, Federica Camarda, Francesca Misceo, Francesco De Vincenzo, Addolorata Corrado, Francesco Paolo Cantatore, Federico Perosa, Giuliana Guggino, Paola Cipriani, Francesco Ciccia, Roberto Giacomelli, Luca Navarini
Scientific Reports, 2025
This study aims to evaluate the impact of pain catastrophizing (PC) on disease activity in patients with rheumatoid arthritis (RA) and to explore, in the same participants, if this association is related or not with anxiety and depression, which have been related to catastrophization in patients with chronic pain. A multi-center, observational study has been conducted on 158 RA patients from six Rheumatology Clinics. Participants were assessed using the Clinical Disease Activity Index (CDAI) and Simple Disease Activity Index (SDAI) and Disease Activity Score on 28 joints- C reactive protein (DAS28-CRP). Pain Catastrophizing, with its domains of Helplessness, Rumination and Magnification, was analyzed through Pain Catastrophizing Scale (PCS). Statistical analyses included univariable and multivariable regressions, to identify associations between disease activity and PC. Results revealed that higher PCS scores were significantly associated with increased CDAI, SDAI and DAS28-CRP values, indicating higher disease activity. Specifically, the domains of Rumination and Helplessness showed a strong correlation with disease activity, while Magnification did not. These associations persisted independently of anxiety and depression mood, as shown by multivariable regression analysis. Pain catastrophizing, particularly the domains of Rumination and Helplessness, significantly influences disease activity in RA patients, independent of mood disorders. These findings underscore the importance of addressing maladaptive cognitive perceptions of pain in the management of RA, to improve patient outcomes and facilitate disease remission. - Definition of relapse criteria in patients with rapidly progressive systemic sclerosis treated with autologous haemopoietic stem cell transplantation
Nicoletta Del Papa, Myriam Labopin, Manuela Badoglio, Dominique Farge, Jorg Henes, John A. Snowden, Julia Spierings, Claudia Iannone, Tobias Alexander, , Paolo Airò, Norbert Blank, Richard Burt, Corrado Campochiaro, Patricia Carreira, Paola Cipriani, Veronica Codullo, Francesco Del Galdo, Oliver Distler, Armando Gabrielli, Roberto Giacomelli, Serena Guiducci, Anna-Maria Hoffman-Vold, Zora Marjanovic, Ulf Müller Ladner, Maria Carolina Oliveira, Ross Penglase, Gregory Pugnet, Mathieu Puyade, Doron Rimar, Marc Schmalzing, Jan Storek, Marie-Elise Truchetet, Gabriele Valentini, Serena Vettori, Madelon Vonk, Alexandre Voskuyl, Raffaella Greco
Bone Marrow Transplantation, 2025
Systemic sclerosis (SSc) is a rare systemic autoimmune disease characterized by the accumulation of extracellular collagen matrix in tissues and target organs, such as skin, lung, gut, and heart [ 1 ]. The clinical spectrum of SSc is largely heterogeneous, but usually two distinct forms are recognized., i.e., the limited cutaneous (lc) and the diffuse cutaneous (dc) SSc. The two variants strongly differ in the terms of skin extension, type and severity of internal organ involvement, and expected survival. Among patients with dcSSc, a subset may be characterized by a rapidly progressive course with early appearance and quick worsening of skin and internal organ involvement, and consequently a high mortality rate within the first five years after first non-Raynaud phenomenom symptoms [ 2 ]. In these cases of rapidly progressive dcSSc, autologous haematopoietic stem cell transplantation (AHSCT) has been recognized as a standard-of-care therapy option since 2017 [ 3 , 4 , 5 , 6 ]. This statement was the direct consequence of the consistent results obtained in three randomized controlled trials where this procedure had been shown to be superior to traditional immunosuppressive therapy in improving skin involvement, preserving lung function, and reducing mortality rates [ 6 ]. These results have been further confirmed in a recent retrospective study where AHSCT was shown to be superior to rituximab in improving all the above-mentioned outcomes [ 7 ]. Nevertheless, several aspects of AHSCT warrant further consideration. First, transplantation related mortality still exists, although it has been significantly reduced thanks to the important progress made, with better pretransplant evaluation of cardiac and pulmonary involvement and improved selection of patients at lower risk of complications [ 8 ]. Another question to be answered is how long the effects of AHSCT will last. Preliminary data indicate that the incidence of disease progression could happen between 4 and 6 years after transplantation and that disease response varied according to patients [ 9 ]. However, although the observed clinical response after AHSCT has been defined since the early pivotal trials (ASSIT, ASTIS, SCOT) and the absence of response or disease progression after AHSCT is easy to define as its counterpart, no dedicated and validated tools are currently available to precisely define the disease relapse after AHSCT. Acquiring the moment of relapse after prior response to AHSCT may make it easier to adopt therapeutic interventions that may allow to maintain the disease remission induced by AHSCT. - Clinical and Ultrasonographic Assessment of Nail Psoriasis: A Comprehensive Study
Maria Esposito, Lina Maria Magnanimi, Paolo Antonetti, Andrea De Berardinis, Cristina Pellegrini, Emanuele Vagnozzi, Manfredo Bruni, Camilla Gianneramo, Paola Cipriani, Maria Concetta Fargnoli, Antonio Barile, Piero Ruscitti
Dermatology Practical and Conceptual, 2025 - Joint Manifestations in Inflammatory Bowel Diseases, “Red Flags” for the Early Recognition and Management of Related Arthropathies: A Narrative Review
Ilenia Di Cola, Luca Vallocchia, Paola Cipriani, Piero Ruscitti
Journal of Clinical Medicine, 2025 - Short-term effectiveness of guselkumab in psoriatic arthritis patients and axial involvement: results from a real-life multicentre cohort
Piero Ruscitti, Ilenia Pantano, Giulia Cataldi, Martina Gentile, Francesco Arrigoni, Luca Riccio, Sabrina Marrone, Daniele Mauro, Francesco Ursini, Maria Esposito, Antonio Barile, Maria Concetta Fargnoli, Roberto Giacomelli, Francesco Ciccia, Paola Cipriani
Rheumatology, 2025 - Assessment of gene signatures following the inhibition of IL-23: a study to evaluate the mechanistic effects behind the clinical efficacy of guselkumab in patients with psoriatic arthritis
Mirco Mastrangelo, Piero Ruscitti, Manfredo Bruni, Eleonora Lucantonio, Andrea De Berardinis, Antonio Barile, Maria Concetta Fargnoli, Paola Cipriani, Maria Esposito, Cristina Pellegrini
Frontiers in Immunology, 2025 - Imaging findings in patients with axial spondyloarthritis presenting with recurrent fever attacks: data from the international AIDA network spondyloarthritis registry
Nunzia Di Meglio, Cristian Sica, Antonio Vitale, Valeria Caggiano, Armando Perrella, Vito Di Martino, Margherita Di Stefano, Mauro Fratarcangeli, Giulio Bagnacci, Piero Ruscitti, Paola Cipriani, Azadeh Shariat Panahi, Samar Tharwat, Hanan M. Elberashi, Esraa E. Othman, Alessandro Conforti, Linda Lucchetti, Fabrizio Varini, Jurgen Sota, Guillermo Arturo Guaracha-Basañez, Perla Ayumi Kawakami-Campos, Eduardo Martín-Nares, Maissa Thabet, Ben Yahia Wissal, Sukran Erten, Mehmet Akif Eksin, Bahar Özdemir Ulusoy, Patrizia Barone, Santi Papa, Andrea Giugno, Stefano Gentileschi, Carla Gaggiano, Simona Buonanno, Soad Hashad, Halah Etayari, Abdurrahman Tufan, Gaafar Ragab, Ewa Wiesik-Szewczyk, José Hernández-Rodríguez, Alberto Balistreri, Andrea Hinojosa-Azaola, Claudia Fabiani, Bruno Frediani, Luca Cantarini, Maria Antonietta Mazzei
Frontiers in Medicine, 2025 - Development and implementation of the international AIDA network spondylarthritis registry
Valeria Caggiano, Antonio Vitale, Andrea Hinojosa-Azaola, Guillermo Arturo Guaracha-Basañez, Piero Ruscitti, Paola Cipriani, Samar Tharwat, Hanan M. Elberashi, Esraa E. Othman, Alessandro Conforti, Giancarlo Gimignani, Sukran Erten, Patrizia Barone, Maissa Thabet, Jurgen Sota, José Hernández-Rodríguez, Verónica Gómez-Caverzaschi, Gaafar Ragab, Amina Maher, Ezgi Deniz Batu, Perla Ayumi Kawakami-Campos, Jiram Torres-Ruiz, Carla Gaggiano, Abdurrahman Tufan, Hamit Kucuk, Henrique A. Mayrink Giardini, Guiga Ahmed, Mehmet Akif Eksin, Lampros Fotis, Azadeh Shariat Panahi, Stefano Gentileschi, Ibrahim A. Almaghlouth, Petros P. Sfikakis, George E. Fragoulis, Costanza Monterosso, Daniela Opris-Belinski, Soad Hashad, Nunzia Di Meglio, Cristian Sica, Bahar Özdemir Ulusoy, Alejandra de-la-Torre, Ewa Wiesik-Szewczyk, Katarzyna Rybak, Alberto Balistreri, Claudia Fabiani, Maria Antonietta Mazzei, Bruno Frediani, Luca Cantarini
Frontiers in Medicine, 2025 - The effects of suppressing inflammation by tofacitinib may simultaneously improve glycaemic parameters and inflammatory markers in rheumatoid arthritis patients with comorbid type 2 diabetes: a proof-of-concept, open, prospective, clinical study
Claudia Di Muzio, Ilenia Di Cola, Azadeh Shariat Panahi, Francesco Ursini, Annamaria Iagnocco, Roberto Giacomelli, Paola Cipriani, Piero Ruscitti
Arthritis Research and Therapy, 2024 - Diminished expression of the ubiquitin-proteasome system in early treatment-naïve patients with rheumatoid arthritis and concomitant type 2 diabetes may be linked to IL-1 pathway hyper-activity; results from PEAC cohort
Piero Ruscitti, Damiano Currado, Felice Rivellese, Marta Vomero, Luca Navarini, Paola Cipriani, Costantino Pitzalis, Roberto Giacomelli
Arthritis Research and Therapy, 2024 - Pain catastrophizing negatively impacts drug retention rate in patients with Psoriatic Arthritis and axial Spondyloarthritis: results from a 2-years perspective multicenter GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica) study
Damiano Currado, Francesca Saracino, Piero Ruscitti, Annalisa Marino, Ilenia Pantano, Marta Vomero, Onorina Berardicurti, Viktoriya Pavlych, Claudio Di Vico, Francesco Caso, Luisa Costa, Marco Tasso, Federica Camarda, Francesca Misceo, Francesco De Vincenzo, Addolorata Corrado, Luisa Arcarese, Amelia Rigon, Marta Vadacca, Erika Corberi, Lyubomyra Kun, Francesca Trunfio, Andrea Pilato, Ludovica Lamberti, Francesco Paolo Cantatore, Federico Perosa, Giuliana Guggino, Raffaele Scarpa, Paola Cipriani, Francesco Ciccia, Roberto Giacomelli, Luca Navarini
Arthritis Research and Therapy, 2024 - Clinical and subclinical atherosclerosis in patients with systemic sclerosis: an observational, multicentre study of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale)
Vasiliki Liakouli, Ignazio Verde, Piero Ruscitti, Claudio Di Vico, Annarita Ruggiero, Daniele Mauro, Giulio Forte, Luca Navarini, Stefano Di Donato, Pietro Bearzi, Marco Minerba, Nicoletta Bertolini, Elvira Favoino, Giulia Maria Destro Castaniti, Roberto D'Alessandro, Virginia Berlengiero, Noemi Italiano, Francesca Bellisai, Francesco Caso, Giuliana Guggino, Ada Corrado, Paola Triggianese, Alberto Lo Gullo, Giuseppe Mandraffino, Luca Cantarini, Paola Cipriani, Francesco Paolo Cantatore, Maria Sole Chimenti, Federico Perosa, Annamaria Iagnocco, Ludovico Docimo, Roberto Giacomelli, Francesco Ciccia
Clinical and Experimental Rheumatology, 2024 - Tailoring the treatment of inflammatory rheumatic diseases by a better stratification and characterization of the clinical patient heterogeneity. Findings from a systematic literature review and experts' consensus
Piero Ruscitti, Yannick Allanore, Chiara Baldini, Giuseppe Barilaro, Elena Bartoloni Bocci, Pietro Bearzi, Elisa Bellis, Onorina Berardicurti, Alice Biaggi, Michele Bombardieri, Luca Cantarini, Francesco Paolo Cantatore, Roberto Caporali, Francesco Caso, Ricard Cervera, Francesco Ciccia, Paola Cipriani, Loukas Chatzis, Serena Colafrancesco, Fabrizio Conti, Erika Corberi, Luisa Costa, Damiano Currado, Maurizio Cutolo, Salvatore D'Angelo, Francesco Del Galdo, Ilenia Di Cola, Stefano Di Donato, Oliver Distler, Bernardo D'Onofrio, Andrea Doria, Bruno Fautrel, Serena Fasano, Eugen Feist, Benjamin A. Fisher, Marco Gabini, Saviana Gandolfo, Mariele Gatto, Irene Genovali, Roberto Gerli, Rosa Daniela Grembiale, Giuliana Guggino, Anna Maria Hoffmann-Vold, Annamaria Iagnocco, Francesco Salvatore Iaquinta, Vasiliki Liakouli, Menelaos N. Manoussakis, Annalisa Marino, Daniele Mauro, Carlomaurizio Montecucco, Marta Mosca, Saverio Naty, Luca Navarini, Daniele Occhialini, Valeria Orefice, Federico Perosa, Carlo Perricone, Andrea Pilato, Costantino Pitzalis, Elena Pontarini, Marcella Prete, Roberta Priori, Felice Rivellese, Piercarlo Sarzi-Puttini, Raffaele Scarpa, Giandomenico Sebastiani, Carlo Selmi, Yehuda Shoenfeld, Giovanni Triolo, Francesca Trunfio, Qingran Yan, Athanasios G. Tzioufas, Roberto Giacomelli
Autoimmunity Reviews, 2024 - The Systemic Score May Identify Life-Threatening Evolution in Still Disease: Data from the GIRRCS AOSD-Study Group and the AIDA Network Still Disease Registry
Piero Ruscitti, Francesco Masedu, Antonio Vitale, Valeria Caggiano, Ilenia Di Cola, Paola Cipriani, Marco Valenti, Henrique A Mayrink Giardini, Isabele Parente de Brito Antonelli, Marilia Ambiel Dagostin, Giuseppe Lopalco, Florenzo Iannone, Morrone Maria, Ibrahim A Almaghlouth, Kazi Nur Asfina, Hebatallah Hamed Ali, Francesco Ciccia, Daniela Iacono, Ilenia Pantano, Daniele Mauro, Petros P Sfikakis, Maria Tektonidou, Katerina Laskari, Onorina Berardicurti, Lorenzo Dagna, Alessandro Tomelleri, Abdurrahman Tufan, Rıza Can Kardas, Andrea Hinojosa‐Azaola, Eduardo Martín‐Nares, Perla Ayumi Kawakami‐Campos, Gaafar Ragab, Mohamed Tharwat Hegazy, Haner Direskeneli, Fatma Alibaz‐Oner, Lampros Fotis, Paolo Sfriso, Marcello Govoni, Francesco La Torre, Maria Cristina Maggio, Carlomaurizio Montecucco, Ludovico De Stefano, Serena Bugatti, Silvia Rossi, Joanna Makowska, Emanuela Del Giudice, Giacomo Emmi, Elena Bartoloni, José Hernández‐Rodríguez, Giovanni Conti, Alma Nunzia Olivieri, Alberto Lo Gullo, Gabriele Simonini, Ombretta Viapiana, Ewa Wiesik‐Szewczyk, Sukran Erten, Francesco Carubbi, Amato De Paulis, Armin Maier, Samar Tharwat, Stefania Costi, Annamaria Iagnocco, Gian Domenico Sebastiani, Antonio Gidaro, Antonio Luca Brucato, Anastasios Karamanakos, Nurullah Akkoç, Francesco Caso, Luisa Costa, Marcella Prete, Federico Perosa, Fabiola Atzeni, Giuliana Guggino, Claudia Fabiani, Bruno Frediani, Roberto Giacomelli, Luca Cantarini
Arthritis and Rheumatology, 2024 - Association between Patient Acceptable Symptom State and disease activity in psoriatic arthritis is disrupted by confounders, including comorbid fibromyalgia
Luca Navarini, Damiano Currado, Andrea Pilato, Annalisa Marino, Alice Biaggi, Stefano Di Donato, Onorina Berardicurti, Marta Vomero, Lyubomyra Kun, Luisa Arcarese, Amelia Rigon, Marta Vadacca, Pietro Bearzi, Piero Ruscitti, Paola Cipriani, Annamaria Iagnocco, Roberto Giacomelli
Clinical and Experimental Rheumatology, 2024 - The Evaluation of Effectiveness and Safety of Guselkumab in Patients with Psoriatic Arthritis in a Prospective Multicentre “Real-Life” Cohort Study
Piero Ruscitti, Giulia Cataldi, Martina Gentile, Alice Dionisi, Paola Volpe, Annacarla Finucci, Lucrezia Verardi, Claudia Di Muzio, Noemi Italiano, Eleonora Celletti, Myriam Di Penta, Ilenia Di Cola, Alessandra Marrelli, Alessia Alfonsi, Francesco Delle Monache, Francesco Cipollone, Marco Gabini, Paola Cipriani
Rheumatology and Therapy, 2024 - The assessment of the drug retention rate of secukinumab in patients with psoriatic arthritis in a real-life multicentre cohort
Piero Ruscitti, Ilenia Pantano, Fabio Massimo Perrotta, Eleonora Celletti, Paola Volpe, Maria Sofia Ciliento, Valentina Marino, Maura Raimondi, Emanuela Gaggiano, Daniele Mauro, Giulia Cataldi, Noemi Italiano, Claudia Di Muzio, Luca Navarini, Raffaele Zicolella, Marco Gabini, Francesco Cipollone, Ennio Lubrano, Roberto Giacomelli, Francesco Ciccia, Paola Cipriani
Clinical and Experimental Rheumatology, 2024 - Correction: Clinical and laboratory features associated with macrophage activation syndrome in Still’s disease: data from the international AIDA Network Still’s Disease Registry (Internal and Emergency Medicine, (2023), 18, 8, (2231-2243), 10.1007/s11739-023-03408-3)
Paola Triggianese, Antonio Vitale, Giuseppe Lopalco, Henrique Ayres Mayrink Giardini, Francesco Ciccia, Ibrahim Al-Maghlouth, Piero Ruscitti, Petros Paul Sfikakis, Florenzo Iannone, Isabele Parente de Brito Antonelli, Martina Patrone, Kazi Nur Asfina, Ilenia Di Cola, Katerina Laskari, Carla Gaggiano, Abdurrahman Tufan, Paolo Sfriso, Lorenzo Dagna, Roberto Giacomelli, Andrea Hinojosa-Azaola, Gaafar Ragab, Lampros Fotis, Haner Direskeneli, Veronica Spedicato, Marilia Ambiel Dagostin, Daniela Iacono, Hebatallah Hamed Ali, Paola Cipriani, Jurgen Sota, Riza Can Kardas, Sara Bindoli, Corrado Campochiaro, Luca Navarini, Stefano Gentileschi, Eduardo Martín-Nares, Jiram Torres-Ruiz, Moustafa Ali Saad, Katerina Kourtesi, Fatma Alibaz-Oner, Gizem Sevik, Annamaria Iagnocco, Joanna Makowska, Marcello Govoni, Sara Monti, Maria Cristina Maggio, Francesco La Torre, Emanuela Del Giudice, José Hernández-Rodríguez, Elena Bartoloni, Giacomo Emmi, Maria Sole Chimenti, Armin Maier, Gabriele Simonini, Giovanni Conti, Alma Nunzia Olivieri, Maria Tarsia, Amato De Paulis, Alberto Lo Gullo, Ewa Więsik-Szewczyk, Ombretta Viapiana, Benson Ogunjimi, Samar Tharwat, Sukran Erten, Rossana Nuzzolese, Anastasios Karamanakos, Micol Frassi, Alessandro Conforti, Valeria Caggiano, Achille Marino, Gian Domenico Sebastiani, Antonio Gidaro, Enrico Tombetti, Francesco Carubbi, Giovanni Rubegni, Alessandra Cartocci, Alberto Balistreri, Claudia Fabiani, Bruno Frediani, Luca Cantarini
Internal and Emergency Medicine, 2024 - The assessment of atlantoaxial joint involvement in patients with rheumatoid arthritis, results from an observational “real-life” study
Claudia Di Muzio, Alessandro Conforti, Federico Bruno, Damiano Currado, Onorina Berardicurti, Luca Navarini, Viktoriya Pavlych, Ilenia Di Cola, Alice Biaggi, Stefano Di Donato, Annalisa Marino, Sebastiano Lorusso, Francesco Ursini, Antonio Barile, Carlo Masciocchi, Paola Cipriani, Roberto Giacomelli, Piero Ruscitti
Scientific Reports, 2023 - Derivation and validation of four patient clusters in Still's disease, results from GIRRCS AOSD-study group and AIDA Network Still Disease Registry
Piero Ruscitti, Francesco Masedu, Antonio Vitale, Ilenia Di Cola, Valeria Caggiano, Claudia Di Muzio, Paola Cipriani, Marco Valenti, Onorina Berardicurti, Luca Navarini, Daniela Iacono, Ilenia Pantano, Daniele Mauro, Francesco Ciccia, Silvia Rossi, Ludovico De Stefano, Sara Monti, Serena Bugatti, Carlomaurizio Montecucco, Francesco Caso, Luisa Costa, Marcella Prete, Federico Perosa, Annamaria Iagnocco, Fabiola Atzeni, Giuliana Guggino, Henrique Giardini, Isabele Parente de Brito Antonelli, Ibrahim A Almaghlouth, Kazi Asfina, Haner Direskeneli, Fatma Alibaz-Oner, Gizem Sevik, Abdurrahman Tufan, Petros P Sfikakis, Francesco La Torre, Andrea Hinojosa-Azaola, Eduardo Martín-Nares, Jiram Torres-Ruiz, Gafaar Ragab, Maria Cristina Maggio, Joanna Makowska, Emanuela Del Giudice, Elena Bartoloni, Giacomo Emmi, Marcello Govoni, Alberto Lo Gullo, Giuseppe Lopalco, Gabriele Simonini, Lampros Fotis, Benson Ogunjimi, Samar Tharwat, Bruno Frediani, Armin Maier, Francesco Carubbi, Lorenzo Dagna, Sukran Erten, Antonio Gidaro, José Hernández-Rodríguez, Paolo Sfriso, Claudia Fabiani, Roberto Giacomelli, Luca Cantarini
Rmd Open, 2023 - Clinical and laboratory features associated with macrophage activation syndrome in Still’s disease: data from the international AIDA Network Still’s Disease Registry
Paola Triggianese, Antonio Vitale, Giuseppe Lopalco, Henrique Ayres Mayrink Giardini, Francesco Ciccia, Ibrahim Al-Maghlouth, Piero Ruscitti, Petros Paul Sfikakis, Florenzo Iannone, Isabele Parente de Brito Antonelli, Martina Patrone, Kazi Nur Asfina, Ilenia Di Cola, Katerina Laskari, Carla Gaggiano, Abdurrahman Tufan, Paolo Sfriso, Lorenzo Dagna, Roberto Giacomelli, Andrea Hinojosa-Azaola, Gaafar Ragab, Lampros Fotis, Haner Direskeneli, Veronica Spedicato, Marilia Ambiel Dagostin, Daniela Iacono, Hebatallah Hamed Ali, Paola Cipriani, Jurgen Sota, Riza Can Kardas, Sara Bindoli, Corrado Campochiaro, Luca Navarini, Stefano Gentileschi, Eduardo Martín-Nares, Jiram Torres-Ruiz, Moustafa Ali Saad, Katerina Kourtesi, Fatma Alibaz-Oner, Gizem Sevik, Annamaria Iagnocco, Joanna Makowska, Marcello Govoni, Sara Monti, Maria Cristina Maggio, Francesco La Torre, Emanuela Del Giudice, José Hernández-Rodríguez, Elena Bartoloni, Giacomo Emmi, Maria Sole Chimenti, Armin Maier, Gabriele Simonini, Giovanni Conti, Alma Nunzia Olivieri, Maria Tarsia, Amato De Paulis, Alberto Lo Gullo, Ewa Więsik-Szewczyk, Ombretta Viapiana, Benson Ogunjimi, Samar Tharwat, Sukran Erten, Rossana Nuzzolese, Anastasios Karamanakos, Micol Frassi, Alessandro Conforti, Valeria Caggiano, Achille Marino, Gian Domenico Sebastiani, Antonio Gidaro, Enrico Tombetti, Francesco Carubbi, Giovanni Rubegni, Alessandra Cartocci, Alberto Balistreri, Claudia Fabiani, Bruno Frediani, Luca Cantarini
Internal and Emergency Medicine, 2023 - Clinical correlates of a subset of anti-fibroblast antibodies in systemic sclerosis
Elvira Favoino, Paola Cipriani, Vasiliki Liakouli, Addolorata Corrado, Luca Navarini, Marta Vomero, Adriana Sisto, Rosa Daniela Grembiale, Francesco Ciccia, Francesco P. Cantatore, Piero Ruscitti, Roberto Giacomelli, Federico Perosa
Clinical Immunology, 2023 - The administration of methotrexate in patients with Still's disease, “real-life” findings from AIDA Network Still Disease Registry
Piero Ruscitti, Jurgen Sota, Antonio Vitale, Giuseppe Lopalco, Florenzo Iannone, Maria Morrone, Henrique Ayres Mayrink Giardini, Marília Ambuel D'Agostin, Isabelle Parente de Brito Antonelli, Ibrahim Almaghlouth, Kazi Nur Asfina, Najma Khalil, Petros P. Sfikakis, Katerina Laskari, Maria Tektonidou, Francesco Ciccia, Daniela Iacono, Flavia Riccio, Gaafar Ragab, Mohamed A. Hussein, Marcello Govoni, Francesca Ruffilli, Haner Direskeneli, Fatma Alibaz-Oner, Roberto Giacomelli, Luca Navarini, Elena Bartoloni, Ilenia Riccucci, Eduardo Martín-Nares, Jiram Torres-Ruiz, Paola Cipriani, Ilenia Di Cola, José Hernández-Rodríguez, Verónica Gómez-Caverzaschi, Lorenzo Dagna, Alessandro Tomelleri, Joanna Makowska, Olga Brzezinska, Annamaria Iagnocco, Elisa Bellis, Valeria Caggiano, Carla Gaggiano, Maria Tarsia, Ilaria Mormile, Giacomo Emmi, Paolo Sfriso, Sara Monti, Şükran Erten, Emanuela Del Giudice, Riccardo Lubrano, Giovanni Conti, Alma Nunzia Olivieri, Alberto Lo Gullo, Samar Tharwat, Anastasios Karamanakos, Antonio Gidaro, Maria Cristina Maggio, Francesco La Torre, Fabio Cardinale, Benson Ogunjimi, Armin Maier, Gian Domenico Sebastiani, Daniela Opris-Belinski, Micol Frassi, Ombretta Viapiana, Emanuele Bizzi, Francesco Carubbi, Lampros Fotis, Abdurrahman Tufan, Riza Can Kardas, Ewa Więsik-Szewczyk, Karina Jahnz-Różyk, Claudia Fabiani, Bruno Frediani, Alberto Balistreri, Donato Rigante, Luca Cantarini
Seminars in Arthritis and Rheumatism, 2023 - Clinical characteristics of obese patients with adult-onset Still's disease. Data from a large multicentre cohort
Ilenia Di Cola, Daniela Iacono, Ilenia Pantano, Daniele Mauro, Antonio Vitale, Francesco Caso, Ludovico De Stefano, Marcella Prete, Luca Navarini, Jacopo Ciaffi, Francesco Ursini, Luisa Costa, Federico Perosa, Carlomaurizio Montecucco, Luca Cantarini, Bruno Frediani, Francesco Ciccia, Roberto Giacomelli, Paola Cipriani, Piero Ruscitti
Joint Bone Spine, 2023 - The negative impact of pain catastrophising on disease activity: analyses of data derived from patient-reported outcomes in psoriatic arthritis and axial spondyloarthritis
Damiano Currado, Alice Biaggi, Andrea Pilato, Annalisa Marino, Piero Ruscitti, Ilenia Pantano, Stefano Di Donato, Marta Vomero, Onorina Berardicurti, Viktoriya Pavlych, Claudio Di Vico, Francesco Caso, Luisa Costa, Marco Tasso, Federica Camarda, Francesca Misceo, Francesco De Vincenzo, Addolorata Corrado, Francesco Paolo Cantatore, Federico Perosa, Giuliana Guggino, Raffaele Scarpa, Paola Cipriani, Francesco Ciccia, Roberto Giacomelli, Luca Navarini
Clinical and Experimental Rheumatology, 2023 - Tofacitinib may improve insulin resistance in patients with rheumatoid arthritis and diabetes, implications for disease management and precision medicine approach
Claudia Di Muzio, Francesco Ursini, Annamaria Iagnocco, Paola Cipriani, Roberto Giacomelli, Piero Ruscitti
Autoimmunity Reviews, 2023 - Correspondence on 'Disease activity, cytokines, chemokines and the risk of incident diabetes in rheumatoid arthritis'
Piero Ruscitti, Giorgio Sesti, Paola Cipriani, Roberto Gerli, Roberto Giacomelli
Annals of the Rheumatic Diseases, 2023 - The similar expression of both ferritin and scavenger receptors activation genes in patients with COVID19 and AOSD support their role in the pathogenesis of these diseases and identify a common mechanism at the basis of the “hyperferritinemic syndromes”
Onorina Berardicurti, Luca Navarini, Marta Vomero, Damiano Currado, Alice Biaggi, Annalisa Marino, Pietro Bearzi, Erika Corberi, Amelia Rigon, Luisa Arcarese, Marta Vadacca, Alessia Mattei, Felice Eugenio Agrò, Raffaele Antonelli Incalzi, Federica Sambuco, Francesco Travaglino, Piero Ruscitti, Paola Cipriani, Roberto Giacomelli
Autoimmunity Reviews, 2023 - Cardiometabolic multimorbidity may identify a more severe subset of rheumatoid arthritis, results from a "real-life" study
Piero Ruscitti, Claudia Di Muzio, Alessandro Conforti, Ilenia Di Cola, Viktoriya Pavlych, Luca Navarini, Damiano Currado, Alice Biaggi, Stefano Di Donato, Annalisa Marino, Sebastiano Lorusso, Francesco Ursini, Roberto Giacomelli, Paola Cipriani
Medicine United States, 2023 - Fibroblast expression of CD248 may contribute to exacerbation of microvascular damage during systemic sclerosis
Paola Cipriani, Piero Ruscitti, Ilenia Di Cola, Marta Vomero, Franca Abbruzzese, Elena Di Nino, Rebecca Ross, Francesco Del Galdo, Roberto Giacomelli
Rheumatology United Kingdom, 2023 - Whole body insulin sensitivity is increased in systemic sclerosis
Jacopo Ciaffi, Piero Ruscitti, Ilenia Di Cola, Viktoriya Pavlych, Noemi Italiano, Martina Gentile, Tom Huizinga, Jeska K. de Vries-Bouwstra, Francesco Ursini, Paola Cipriani
Plos One, 2023 - Cytokine profile characterization of naïve patients with psoriasis and psoriatic arthritis: implications for a pathogenic disease continuum
Piero Ruscitti, Maria Esposito, Ilenia Di Cola, Cristina Pellegrini, Andrea De Berardinis, Mirco Mastrangelo, Camilla Gianneramo, Antonio Barile, Maria Concetta Fargnoli, Paola Cipriani
Frontiers in Immunology, 2023 - Cytokine profile, ferritin and multi-visceral involvement characterize macrophage activation syndrome during adult-onset Still's disease
Piero Ruscitti, Francesco Ursini, Onorina Berardicurti, Francesco Masedu, Emanuele Bozzalla Cassione, Susanna Naldi, Ilenia Di Cola, Claudia Di Muzio, Ludovico De Stefano, Elena Di Nino, Luca Navarini, Marta Vomero, Serena Bugatti, Marco Valenti, Erminia Mariani, Annamaria Iagnocco, Carlomaurizio Montecucco, Roberto Giacomelli, Paola Cipriani
Rheumatology United Kingdom, 2023 - The specialized pro-resolving lipid mediator Protectin D1 affects macrophages differentiation and activity in Adult-onset Still’s disease and COVID-19, two hyperinflammatory diseases sharing similar transcriptomic profiles
Luca Navarini, Marta Vomero, Damiano Currado, Onorina Berardicurti, Alice Biaggi, Annalisa Marino, Pietro Bearzi, Erika Corberi, Amelia Rigon, Luisa Arcarese, Alessandro Leuti, Marina Fava, Marta Fogolari, Alessia Mattei, Piero Ruscitti, Ilenia Di Cola, Federica Sambuco, Francesco Travaglino, Silvia Angeletti, Francesco Ursini, Erminia Mariani, Paola Cipriani, Felice Eugenio Agrò, Annamaria Iagnocco, Raffaele Antonelli Incalzi, Mauro Maccarrone, Roberto Giacomelli
Frontiers in Immunology, 2023 - Nail and enthesis assessment in patients with psoriatic disease by high frequency ultrasonography: findings from a single-centre cross-sectional study
Piero Ruscitti, Maria Esposito, Camilla Gianneramo, Ilenia Di Cola, Andrea De Berardinis, Andrea Martinese, Gerard Nkamtse Tochap, Alessandro Conforti, Carlo Masciocchi, Paola Cipriani, Antonio Barile, Maria Concetta Fargnoli
Radiologia Medica, 2022 - Unenhanced Cardiac Magnetic Resonance may improve detection and prognostication of an occult heart involvement in asymptomatic patients with systemic sclerosis
Pierpaolo Palumbo, Piero Ruscitti, Ester Cannizzaro, Onorina Berardicurti, Alessandro Conforti, Annamaria Di Cesare, Ilenia Di Cola, Roberto Giacomelli, Alessandra Splendiani, Antonio Barile, Carlo Masciocchi, Paola Cipriani, Ernesto Di Cesare
Scientific Reports, 2022 - Persistence of C-reactive protein increased levels and high disease activity are predictors of cardiovascular disease in patients with axial spondyloarthritis
Luca Navarini, Damiano Currado, Annalisa Marino, Stefano Di Donato, Alice Biaggi, Francesco Caso, Luisa Costa, Marco Tasso, Piero Ruscitti, Viktoriya Pavlych, Onorina Berardicurti, Antonio Ciancio, Ilenia Pantano, Federica Camarda, Maria Sole Chimenti, Arianna D’Antonio, Francesco Ursini, Addolorata Corrado, Francesco Paolo Cantatore, Roberto Perricone, Giuliana Guggino, Francesco Ciccia, Paola Cipriani, Raffaele Scarpa, Antonella Afeltra, Roberto Giacomelli
Scientific Reports, 2022 - Efficacy and safety of tocilizumab in adult-onset Still's disease: Real-life experience from the international AIDA registry
Jurgen Sota, Antonio Vitale, Giuseppe Lopalco, Rosa Maria R. Pereira, Heitor F. Giordano, Isabele P.B. Antonelli, Joanna Makowska, Olga Brzezińska, Anna Lewandowska-Polak, Piero Ruscitti, Paola Cipriani, Ilenia Di Cola, Marcello Govoni, Francesca Ruffili, Petros P. Sfikakis, Katerina Laskari, Gaafar Ragab, Mohamed A. Hussein, Stefano Gentileschi, Carla Gaggiano, Francesco La Torre, Armin Maier, Giacomo Emmi, Achille Marino, Francesco Ciccia, Paolo Sfriso, Maria Cristina Maggio, Elena Bartoloni, Claudia Lomater, Mohamed Tharwat Hegazy, Maria Tektonidou, Marília A. Dagostin, Aleksandra Opinc, Gian Domenico Sebastiani, Roberto Giacomelli, Emanuela Del Giudice, Alma Nunzia Olivieri, Abdurrahman Tufan, Riza Kan Kardas, Rossana Nuzzolese, Fabio Cardinale, Ewa Więsik-Szewczyk, Parretti Veronica, Maria Tarsia, Florenzo Iannone, Francesca Della Casa, Claudia Fabiani, Bruno Frediani, Alberto Balistreri, Donato Rigante, Luca Cantarini
Seminars in Arthritis and Rheumatism, 2022 - Rheumatoid Arthritis Treatment Options and Type 2 Diabetes: Unravelling the Association
Claudia Di Muzio, Paola Cipriani, Piero Ruscitti
Biodrugs, 2022 - Correction to: Impact of smoking habit on adult-onset Still’s disease prognosis, findings from a multicentre observational study (Clinical Rheumatology, (2022), 41, 3, (641-647), 10.1007/s10067-021-05929-8)
Piero Ruscitti, Ilenia Di Cola, Onorina Berardicurti, Alessandro Conforti, Daniela Iacono, Ilenia Pantano, Gelsomina Rozza, Silvia Rossi, Ludovico De Stefano, Silvia Balduzzi, Antonio Vitale, Francesco Caso, Luisa Costa, Marcella Prete, Luca Navarini, Fabiola Atzeni, Giuliana Guggino, Federico Perosa, Luca Cantarini, Bruno Frediani, Carlomaurizio Montecucco, Francesco Ciccia, Roberto Giacomelli, Paola Cipriani
Clinical Rheumatology, 2022 - The economic burden of fibromyalgia: A systematic literature review
Martina D'Onghia, Jacopo Ciaffi, Piero Ruscitti, Paola Cipriani, Roberto Giacomelli, Jacob N. Ablin, Francesco Ursini
Seminars in Arthritis and Rheumatism, 2022 - Prevalence and characteristics of diffuse idiopathic skeletal hyperostosis (DISH) in Italy
Jacopo Ciaffi, Elena Borlandelli, Gaia Visani, Giancarlo Facchini, Marco Miceli, Piero Ruscitti, Paola Cipriani, Roberto Giacomelli, Francesco Ursini
Radiologia Medica, 2022 - Disparities in the prevalence of clinical features between systemic juvenile idiopathic arthritis and adult-onset Still's disease
Piero Ruscitti, Valentina Natoli, Alessandro Consolaro, Roberta Caorsi, Silvia Rosina, Gabriella Giancane, Roberta Naddei, Ilenia Di Cola, Claudia Di Muzio, Onorina Berardicurti, Daniela Iacono, Ilenia Pantano, Gelsomina Rozza, Silvia Rossi, Ludovico De Stefano, Silvia Balduzzi, Antonio Vitale, Francesco Caso, Luisa Costa, Marcella Prete, Luca Navarini, Annamaria Iagnocco, Fabiola Atzeni, Giuliana Guggino, Federico Perosa, Luca Cantarini, Bruno Frediani, Carlomaurizio Montecucco, Francesco Ciccia, Paola Cipriani, Marco Gattorno, Roberto Giacomelli, Angelo Ravelli
Rheumatology United Kingdom, 2022 - Development and implementation of the AIDA International Registry for patients with Behçet’s disease
Antonio Vitale, Francesca Della Casa, Gaafar Ragab, Ibrahim A. Almaghlouth, Giuseppe Lopalco, Rosa Maria Pereira, Silvana Guerriero, Marcello Govoni, Petros P. Sfikakis, Roberto Giacomelli, Francesco Ciccia, Sara Monti, Piero Ruscitti, Matteo Piga, Claudia Lomater, Abdurrahman Tufan, Daniela Opris-Belinski, Giacomo Emmi, José Hernández-Rodríguez, Ali Şahin, Gian Domenico Sebastiani, Elena Bartoloni, Nurullah Akkoç, Özgül Soysal Gündüz, Marco Cattalini, Giovanni Conti, Gulen Hatemi, Armin Maier, Paola Parronchi, Emanuela Del Giudice, Sukran Erten, Antonella Insalaco, Francesca Li Gobbi, Maria Cristina Maggio, Farhad Shahram, Valeria Caggiano, Mohamed Tharwat Hegazy, Kazi Nur Asfina, Maria Morrone, Leandro L. Prado, Rosanna Dammacco, Francesca Ruffilli, Aikaterini Arida, Luca Navarini, Ilenia Pantano, Lorenzo Cavagna, Alessandro Conforti, Alberto Cauli, Elena Maria Marucco, Hamit Kucuk, Ruxandra Ionescu, Irene Mattioli, Gerard Espinosa, Olga Araújo, Burak Karkaş, Claudia Canofari, Jurgen Sota, Ahmed Hatem Laymouna, Asma. A. Bedaiwi, Sergio Colella, Henrique Ayres M. Giardini, Valeria Albano, Andrea Lo Monaco, George E. Fragoulis, Riza Can Kardas, Virginia Berlengiero, Mohamed A. Hussein, Francesca Ricci, Francesco La Torre, Donato Rigante, Ewa Więsik-Szewczyk, Micol Frassi, Stefano Gentileschi, Gian Marco Tosi, Marilia Ambiel Dagostin, Ayman Abdel-Monem Ahmed Mahmoud, Maria Tarsia, Giovanni Alessio, Rolando Cimaz, Teresa Giani, Carla Gaggiano, Florenzo Iannone, Paola Cipriani, Mariam Mourabi, Veronica Spedicato, Sara Barneschi, Emma Aragona, Alberto Balistreri, Bruno Frediani, Claudia Fabiani, Luca Cantarini, Autoinflammatory Diseases Alliance (AIDA) Network
Internal and Emergency Medicine, 2022 - Adult-onset Still’s disease with elderly onset: results from a multicentre study
Ilenia Di Cola, Claudia Di Muzio, Alessandro Conforti, Daniela Iacono, Ilenia Pantano, Gelsomina Rozza, Silvia Rossi, Ludovico De Stefano, Antonio Vitale, Francesco Caso, Luisa Costa, Marcella Prete, Luca Navarini, Annamaria Iagnocco, Fabiola Atzeni, Giuliana Guggino, Federico Perosa, Luca Cantarini, Bruno Frediani, Serena Bugatti, Carlomaurizio Montecucco, Francesco Ciccia, Roberto Giacomelli, Paola Cipriani, Piero Ruscitti
Clinical and Experimental Rheumatology, 2022 - Assessment of health-related quality of life in patients with adult onset Still disease: Results from a multicentre cross-sectional study
Piero Ruscitti, Gelsomina Rozza, Claudia Di Muzio, Alice Biaggi, Daniela Iacono, Ilenia Pantano, Annamaria Iagnocco, Roberto Giacomelli, Paola Cipriani, Francesco Ciccia
Medicine United States, 2022 - Expanding the spectrum of the hyperferritinemic syndrome, from pathogenic mechanisms to clinical observations, and therapeutic implications
Piero Ruscitti, Ilenia Di Cola, Claudia Di Muzio, Noemi Italiano, Francesco Ursini, Roberto Giacomelli, Paola Cipriani
Autoimmunity Reviews, 2022 - 2-Arachidonoylglycerol Reduces the Production of Interferon-Gamma in T Lymphocytes from Patients with Systemic Lupus Erythematosus
Luca Navarini, Marta Vomero, Stefano Di Donato, Damiano Currado, Onorina Berardicurti, Annalisa Marino, Pietro Bearzi, Alice Biaggi, Matteo Ferrito, Piero Ruscitti, Marina Fava, Alessandro Leuti, Paola Cipriani, Mauro Maccarrone, Roberto Giacomelli
Biomedicines, 2022 - Duration of clinical remission and low disease activity impacts on quality of life and its domains in psoriatic arthritis patients: results from an Italian multicentre study
Luca Navarini, Damiano Currado, Francesco Caso, Luisa Costa, Maria Sole Chimenti, Arianna D'Antonio, Marco Tasso, Mariangela Salvato, Alice Laudisio, Stefano Di Donato, Alice Biaggi, Annalisa Marino, Andrea Picchianti Diamanti, Elena Palmisano, Piero Ruscitti, Onorina Berardicurti, Sabino Germinario, Paola Cipriani, Roberto Perricone, Bruno Laganà, Raffaele Scarpa, Antonella Afeltra, Roberto Giacomelli
Clinical and Experimental Rheumatology, 2022 - Systemic syndromes of rheumatological interest with onset after COVID-19 vaccine administration: a report of 30 cases
Francesco Ursini, Piero Ruscitti, Vincenzo Raimondo, Rossella De Angelis, Fabio Cacciapaglia, Erika Pigatto, Domenico Olivo, Ilenia Di Cola, Felice Galluccio, Francesca Francioso, Rosario Foti, Antonio Gaetano Tavoni, Salvatore D’Angelo, Corrado Campochiaro, Francesca Motta, Maria De Santis, Silvia Bilia, Caterina Bruno, Giacomo De Luca, Marcella Visentini, Jacopo Ciaffi, Luana Mancarella, Veronica Brusi, Martina D’Onghia, Giovanna Cuomo, Enrico Fusaro, Paola Cipriani, Lorenzo Dagna, Serena Guiducci, Riccardo Meliconi, Florenzo Iannone, Annamaria Iagnocco, Roberto Giacomelli, Clodoveo Ferri
Clinical Rheumatology, 2022 - Development and Implementation of the AIDA International Registry for Patients With Undifferentiated Systemic AutoInflammatory Diseases
Francesca Della Casa, Antonio Vitale, Giuseppe Lopalco, Piero Ruscitti, Francesco Ciccia, Giacomo Emmi, Marco Cattalini, Ewa Wiesik-Szewczyk, Maria Cristina Maggio, Benson Ogunjimi, Petros P. Sfikakis, Abdurrahman Tufan, Sulaiman M. Al-Mayouf, Emanuela Del Giudice, Emma Aragona, Francesco La Torre, Jurgen Sota, Sergio Colella, Ilenia Di Cola, Daniela Iacono, Irene Mattioli, Karina Jahnz-Rózyk, Rik Joos, Katerina Laskari, Carla Gaggiano, Anna Abbruzzese, Paola Cipriani, Gelsomina Rozza, Alhanouf AlSaleem, Derya Yildirim, Maria Tarsia, Gaafar Ragab, Francesca Ricci, Fabio Cardinale, Marcelina Korzeniowska, Micol Frassi, Valeria Caggiano, Moustafa Ali Saad, Rosa Maria Pereira, Virginia Berlengiero, Stefano Gentileschi, Silvana Guerriero, Teresa Giani, Viviana Gelardi, Florenzo Iannone, Henrique Ayres Mayrink Giardini, Ibrahim A. Almaghlouth, Riza Can Kardas, Djouher Ait-Idir, Bruno Frediani, Alberto Balistreri, Claudia Fabiani, Donato Rigante, Luca Cantarini
Frontiers in Medicine, 2022 - Tofacitinib May Inhibit Myofibroblast Differentiation from Rheumatoid-Fibroblast-like Synoviocytes Induced by TGF-β and IL-6
Piero Ruscitti, Vasiliki Liakouli, Noemi Panzera, Adriano Angelucci, Onorina Berardicurti, Elena Di Nino, Luca Navarini, Marta Vomero, Francesco Ursini, Daniele Mauro, Vincenza Dolo, Francesco Ciccia, Roberto Giacomelli, Paola Cipriani
Pharmaceuticals, 2022 - Development and Implementation of the AIDA International Registry for Patients With Still's Disease
Antonio Vitale, Francesca Della Casa, Giuseppe Lopalco, Rosa Maria Pereira, Piero Ruscitti, Roberto Giacomelli, Gaafar Ragab, Francesco La Torre, Elena Bartoloni, Emanuela Del Giudice, Claudia Lomater, Giacomo Emmi, Marcello Govoni, Maria Cristina Maggio, Armin Maier, Joanna Makowska, Benson Ogunjimi, Petros P. Sfikakis, Paolo Sfriso, Carla Gaggiano, Florenzo Iannone, Marília A. Dagostin, Ilenia Di Cola, Luca Navarini, Ayman Abdelmonem Ahmed Mahmoud, Fabio Cardinale, Ilenia Riccucci, Maria Pia Paroli, Elena Maria Marucco, Irene Mattioli, Jurgen Sota, Anna Abbruzzese, Isabele P. B. Antonelli, Paola Cipriani, Abdurrahman Tufan, Claudia Fabiani, Mustafa Mahmoud Ramadan, Marco Cattalini, Riza Can Kardas, Gian Domenico Sebastiani, Henrique A. Mayrink Giardini, José Hernández-Rodríguez, Violetta Mastrorilli, Ewa Więsik-Szewczyk, Micol Frassi, Valeria Caggiano, Salvatore Telesca, Heitor F. Giordano, Emmanuele Guadalupi, Teresa Giani, Alessandra Renieri, Sergio Colella, Giulia Cataldi, Martina Gentile, Alessandra Fabbiani, Ibrahim A. Al-Maghlouth, Bruno Frediani, Alberto Balistreri, Donato Rigante, Luca Cantarini
Frontiers in Medicine, 2022 - The hyper-expression of NLRP4 characterizes the occurrence of macrophage activation syndrome assessing STING pathway in adult-onset Still's disease
Piero Ruscitti, Onorina Berardicurti, Ilenia Di Cola, Claudia Di Muzio, Elena Di Nino, Roberto Giacomelli, Paola Cipriani
Clinical and Experimental Immunology, 2022 - Development and Implementation of the AIDA International Registry for Patients with Non-Infectious Uveitis
Francesca Della Casa, Antonio Vitale, Silvana Guerriero, Jurgen Sota, Rolando Cimaz, Gaafar Ragab, Piero Ruscitti, Rosa Maria R. Pereira, Francesca Minoia, Emanuela Del Giudice, Giacomo Emmi, Claudia Lomater, Sara Monti, Claudia Canofari, Carla Gaggiano, Giovanni Alessio, Elisabetta Miserocchi, Alessandro Conforti, Marilia A. Dagostin, Chiara Mapelli, Maria Pia Paroli, Veronica Parretti, Valeria Albano, Rosa Favale, Luca Marelli, Mohamed Tharwat Hegazy, Paola Cipriani, Isabele P. B. Antonelli, Valeria Caggiano, Emma Aragona, Ahmed Hatem Laymouna, Gian Marco Tosi, Maria Tarsia, Marco Cattalini, Francesco La Torre, Giuseppe Lopalco, Ewa Więsik-Szewczyk, Micol Frassi, Stefano Gentileschi, Heitor F. Giordano, Bruno Frediani, Samuel K. Shinjo, Donato Rigante, Petros P. Sfikakis, Alberto Balistreri, Mohamed A. Hussein, Rana Hussein Amin, Luca Cantarini, Claudia Fabiani, and
Ophthalmology and Therapy, 2022 - Impact of smoking habit on adult-onset Still’s disease prognosis, findings from a multicentre observational study
Piero Ruscitti, Ilenia Di Cola, Onorina Berardicurti, Alessandro Conforti, Daniela Iacono, Ilenia Pantano, Gelsomina Rozza, Silvia Rossi, Ludovico De Stefano, Silvia Balduzzi, Antonio Vitale, Francesco Caso, Luisa Costa, Marcella Prete, Luca Navarini, Fabiola Atzeni, Giuliana Guggino, Federico Perosa, Luca Cantarini, Bruno Frediani, Carlomaurizio Montecucco, Francesco Ciccia, Roberto Giacomelli, Paola Cipriani
Clinical Rheumatology, 2022 - Long-term Safety of Rituximab in Primary Sjögren Syndrome: The Experience of a Single Center
Onorina Berardicurti, Viktoriya Pavlych, Ilenia Di Cola, Piero Ruscitti, Paola Di Benedetto, Luca Navarini, Annalisa Marino, Paola Cipriani, Roberto Giacomelli
Journal of Rheumatology, 2022 - Perspectives on the use of non-biological pharmacotherapy for adult-onset Still’s disease
Ilenia Di Cola, Paola Cipriani, Piero Ruscitti
Expert Opinion on Pharmacotherapy, 2022 - Novel biomarker for pulmonary vascular disease in systemic sclerosis patients
Elvira Favoino, Giacomo Catacchio, Alessandra Mininni, Piero Ruscitti, Valeria Riccieri, Vasiliki Liakouli, Addolorata Corrado, Luca Navarini, Francesco Ciccia, Paola Cipriani, Francesco Paolo Cantatore, Guido Valesini, Roberto Giacomelli, Federico Perosa
Clinical and Experimental Rheumatology, 2022 - The Effect of Ketogenic Diet on Inflammatory Arthritis and Cardiovascular Health in Rheumatic Conditions: A Mini Review
Jacopo Ciaffi, Dmitri Mitselman, Luana Mancarella, Veronica Brusi, Lucia Lisi, Piero Ruscitti, Paola Cipriani, Riccardo Meliconi, Roberto Giacomelli, Claudio Borghi, Francesco Ursini
Frontiers in Medicine, 2021 - The clinical heterogeneity of adult onset Still's disease may underlie different pathogenic mechanisms. Implications for a personalised therapeutic management of these patients
Piero Ruscitti, Onorina Berardicurti, Roberto Giacomelli, Paola Cipriani
Seminars in Immunology, 2021 - Pathogenic implications, incidence, and outcomes of COVID-19 in autoimmune inflammatory joint diseases and autoinflammatory disorders
Piero Ruscitti, Alessandro Conforti, Paola Cipriani, Roberto Giacomelli, Marco Tasso, Luisa Costa, Francesco Caso
Advances in Rheumatology, 2021 - The joint involvement in adult onset Still's disease is characterised by a peculiar magnetic resonance imaging and a specific transcriptomic profile
Piero Ruscitti, Antonio Barile, Onorina Berardicurti, Sonia Iafrate, Paola Di Benedetto, Antonio Vitale, Francesco Caso, Luisa Costa, Federico Bruno, Francesco Ursini, Luca Navarini, Federica Sensini, Raffaele Scarpa, Bruno Frediani, Luca Cantarini, Carlo Masciocchi, Roberto Giacomelli, Paola Cipriani
Scientific Reports, 2021 - Blocking Jak/STAT signalling using tofacitinib inhibits angiogenesis in experimental arthritis
Paola Di Benedetto, Piero Ruscitti, Onorina Berardicurti, Noemi Panzera, Nicolò Grazia, Mauro Di Vito Nolfi, Barbara Di Francesco, Luca Navarini, Antonio Maurizi, Nadia Rucci, Anna Maria Teti, Francesca Zazzeroni, Giuliana Guggino, Francesco Ciccia, Vincenza Dolo, Edoardo Alesse, Paola Cipriani, Roberto Giacomelli
Arthritis Research and Therapy, 2021 - Evaluating the multivisceral involvement on adult-onset Still’s disease to retrieve imaging-based differences in patients with and without macrophage activation syndrome: results from a single-centre observational study
Ilenia Di Cola, Federico Bruno, Onorina Berardicurti, Riccardo Monti, Alessandro Conforti, Alessandra Di Sibio, Viktoriya Pavlych, Carlo Masciocchi, Antonio Barile, Paola Cipriani, Piero Ruscitti
Clinical Rheumatology, 2021 - Dissecting the clinical heterogeneity of adult-onset Still's disease: Results from a multi-dimensional characterization and stratification
Onorina Berardicurti, Alessandro Conforti, Daniela Iacono, Ilenia Pantano, Francesco Caso, Giacomo Emmi, Rosa Daniela Grembiale, Francesco Paolo Cantatore, Fabiola Atzeni, Federico Perosa, Raffaele Scarpa, Giuliana Guggino, Francesco Ciccia, Roberto Giacomelli, Paola Cipriani, Piero Ruscitti
Rheumatology United Kingdom, 2021 - Occurrence and predictive factors of high blood pressure, type 2 diabetes, and metabolic syndrome in rheumatoid arthritis: Findings from a 3-year, multicentre, prospective, observational study
Clinical and Experimental Rheumatology, 2021 - Incidence of venous thromboembolism in rheumatoid arthritis, results from a “real-life” cohort and an appraisal of available literature
Alessandro Conforti, Onorina Berardicurti, Viktoriya Pavlych, Ilenia Di Cola, Paola Cipriani, Piero Ruscitti
Medicine United States, 2021 - Endothelial-to-mesenchymal transition in systemic sclerosis
P Di Benedetto, P Ruscitti, O Berardicurti, M Vomero, L Navarini, V Dolo, P Cipriani, R Giacomelli
Clinical and Experimental Immunology, 2021 - Association Between Minor Salivary Gland Biopsy During Sjӧgren’s Syndrome and Serologic Biomarkers: A Systematic Review and Meta-Analysis
Onorina Berardicurti, Piero Ruscitti, Paola Di Benedetto, Settimio D’Andrea, Luca Navarini, Annalisa Marino, Paola Cipriani, Roberto Giacomelli
Frontiers in Immunology, 2021 - The pathogenic role of interferons in the hyperinflammatory response on adult-onset still’s disease and macrophage activation syndrome: Paving the way towards new therapeutic targets
Ilenia Di Cola, Piero Ruscitti, Roberto Giacomelli, Paola Cipriani
Journal of Clinical Medicine, 2021 - Benefits of anakinra versus TNF inhibitors in rheumatoid arthritis and type 2 diabetes: Long-term findings from participants furtherly followed-up in the TRACK study, a multicentre, open-label, randomised, controlled trial
Clinical and Experimental Rheumatology, 2021 - Beyond the joints, the extra-articular manifestations in rheumatoid arthritis
Alessandro Conforti, Ilenia Di Cola, Viktoriya Pavlych, Piero Ruscitti, Onorina Berardicurti, Francesco Ursini, Roberto Giacomelli, Paola Cipriani
Autoimmunity Reviews, 2021 - The growing role of precision medicine for the treatment of autoimmune diseases; results of a systematic review of literature and Experts’ Consensus
Roberto Giacomelli, Antonella Afeltra, Elena Bartoloni, Onorina Berardicurti, Michele Bombardieri, Alessandra Bortoluzzi, Francesco Carubbi, Francesco Caso, Ricard Cervera, Francesco Ciccia, Paola Cipriani, Emmanuel Coloma-Bazán, Fabrizio Conti, Luisa Costa, Salvatore D’Angelo, Oliver Distler, Eugen Feist, Nathan Foulquier, Marco Gabini, Vanessa Gerber, Roberto Gerli, Rosa Daniela Grembiale, Giuliana Guggino, Ariela Hoxha, Annamaria Iagnocco, Suzana Jordan, Bashar Kahaleh, Kim Lauper, Vasiliki Liakouli, Ennio Lubrano, Domenico Margiotta, Saverio Naty, Luca Navarini, Federico Perosa, Carlo Perricone, Roberto Perricone, Marcella Prete, Jacques-Olivier Pers, Costantino Pitzalis, Roberta Priori, Felice Rivellese, Amelia Ruffatti, Piero Ruscitti, Raffaele Scarpa, Yehuda Shoenfeld, Giovanni Triolo, Athanasios Tzioufas
Autoimmunity Reviews, 2021 - Erratum: Vitamin D increases the production of IL-10 by regulatory T cells in patients with systemic sclerosis (Clinical and experimental rheumatology (2019) 37 Suppl 119 4 (76-81))
Clinical and Experimental Rheumatology, 2020 - Pro-inflammatory properties of H-ferritin on human macrophages, ex vivo and in vitro observations
Piero Ruscitti, Paola Di Benedetto, Onorina Berardicurti, Noemi Panzera, Nicolò Grazia, Anna Rita Lizzi, Paola Cipriani, Yehuda Shoenfeld, Roberto Giacomelli
Scientific Reports, 2020 - Haematopoietic stem cell transplantation in systemic sclerosis: Challenges and perspectives
Paola Di Benedetto, Piero Ruscitti, Paola Cipriani, Roberto Giacomelli
Autoimmunity Reviews, 2020 - Severe COVID-19 and related hyperferritinaemia: more than an innocent bystander?
Piero Ruscitti, Onorina Berardicurti, Antonio Barile, Paola Cipriani, Yehuda Shoenfeld, Annamaria Iagnocco, Roberto Giacomelli
Annals of the Rheumatic Diseases, 2020 - Mortality in tocilizumab-treated patients with COVID-19: a systematic review and meta-analysis
Clinical and Experimental Rheumatology, 2020 - Safety and efficacy of certolizumab pegol in a real-life cohort of patients with psoriasis and psoriatic arthritis
Francesco Carubbi, Rosaria Fidanza, Maria Palmieri, Alessandra Ventura, Sara Tambone, Paola Cipriani, Roberto Giacomelli, Maria Concetta Fargnoli
Journal of Dermatological Treatment, 2020 - Hepatitis e Virus and rheumatic diseases: What do rheumatologists need to know?
Salvatore Di Bartolomeo, Francesco Carubbi, Paola Cipriani
BMC Rheumatology, 2020 - Response to: Correspondence on Lung involvement in macrophage activation syndrome and severe COVID-19: Results from a cross-sectional study to assess clinical, laboratory and artificial intelligence-radiological differences' by Ruscitti et al ' by Chen et al
Piero Ruscitti, Federico Bruno, Onorina Berardicurti, Chiara Acanfora, Viktoriya Pavlych, Pierpaolo Palumbo, Alessandro Conforti, Francesco Carubbi, Ilenia Di Cola, Paola Di Benedetto, Paola Cipriani, Davide Grassi, Carlo Masciocchi, Annamaria Iagnocco, Antonio Barile, Roberto Giacomelli
Annals of the Rheumatic Diseases, 2020 - Lung involvement in macrophage activation syndrome and severe COVID-19: Results from a cross-sectional study to assess clinical, laboratory and artificial intelligence-radiological differences
Piero Ruscitti, Federico Bruno, Onorina Berardicurti, Chiara Acanfora, Viktoriya Pavlych, Pierpaolo Palumbo, Alessandro Conforti, Francesco Carubbi, Ilenia Di Cola, Paola Di Benedetto, Paola Cipriani, Davide Grassi, Carlo Masciocchi, Annamaria Iagnocco, Antonio Barile, Roberto Giacomelli
Annals of the Rheumatic Diseases, 2020 - Ferritin and C-reactive protein are predictive biomarkers of mortality and macrophage activation syndrome in adult onset Still's disease. Analysis of the multicentre Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort
Paola Di Benedetto, Paola Cipriani, Daniela Iacono, Ilenia Pantano, Francesco Caso, Giacomo Emmi, Rosa Daniela Grembiale, Francesco Paolo Cantatore, Fabiola Atzeni, Federico Perosa, Raffaele Scarpa, Giuliana Guggino, Francesco Ciccia, Roberto Giacomelli, Piero Ruscitti
Plos One, 2020 - Parenchymal lung disease in adult onset Still's disease: An emergent marker of disease severity - Characterisation and predictive factors from Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort of patients
Piero Ruscitti, Onorina Berardicurti, Daniela Iacono, Ilenia Pantano, Vasiliki Liakouli, Francesco Caso, Giacomo Emmi, Rosa Daniela Grembiale, Francesco Paolo Cantatore, Fabiola Atzeni, Federico Perosa, Raffaele Scarpa, Giuliana Guggino, Francesco Ciccia, Antonio Barile, Paola Cipriani, Roberto Giacomelli
Arthritis Research and Therapy, 2020 - Glucocorticoids in rheumatoid arthritis: the silent companion in the therapeutic strategy
Onorina Berardicurti, Piero Ruscitti, Viktoriya Pavlych, Alessandro Conforti, Roberto Giacomelli, Paola Cipriani
Expert Review of Clinical Pharmacology, 2020 - Interleukin-32 in systemic sclerosis, a potential new biomarker for pulmonary arterial hypertension
Paola Di Benedetto, Giuliana Guggino, Giovanna Manzi, Piero Ruscitti, Onorina Berardicurti, Noemi Panzera, Nicolò Grazia, Roberto Badagliacca, Valeria Riccieri, Carmine Dario Vizza, Ganna Radchenko, Vasiliki Liakouli, Francesco Ciccia, Paola Cipriani, Roberto Giacomelli
Arthritis Research and Therapy, 2020 - Severe COVID-19, Another Piece in the Puzzle of the Hyperferritinemic Syndrome. An Immunomodulatory Perspective to Alleviate the Storm
Piero Ruscitti, Onorina Berardicurti, Paola Di Benedetto, Paola Cipriani, Annamaria Iagnocco, Yehuda Shoenfeld, Roberto Giacomelli
Frontiers in Immunology, 2020 - Adipose stromal vascular fraction and regenerative therapy in SSc: Response to the article by Magalon et al
Paola Di Benedetto, Paola Cipriani, Piero Ruscitti, Vasiliki Liakouli, Roberto Giacomelli
Annals of the Rheumatic Diseases, 2020 - Comparison of Early vs. Delayed Anakinra Treatment in Patients With Adult Onset Still's Disease and Effect on Clinical and Laboratory Outcomes
Antonio Vitale, Giulio Cavalli, Piero Ruscitti, Jurgen Sota, Serena Colafrancesco, Roberta Priori, Guido Valesini, Lorenza Maria Argolini, Elena Baldissera, Elena Bartoloni, Daniele Cammelli, Giovanni Canestrari, Elena Cavallaro, Maria Grazia Massaro, Paola Cipriani, Ginevra De Marchi, Salvatore De Vita, Giacomo Emmi, Micol Frassi, Roberto Gerli, Elisa Gremese, Florenzo Iannone, Marco Fornaro, Anna Paladini, Giuseppe Lopalco, Raffaele Manna, Alessandro Mathieu, Carlomaurizio Montecucco, Marta Mosca, Ilaria Piazza, Matteo Piga, Irene Pontikaki, Micol Romano, Silvia Rossi, Maurizio Rossini, Elena Silvestri, Chiara Stagnaro, Rosaria Talarico, Bruno Frediani, Angela Tincani, Ombretta Viapiana, Gianfranco Vitiello, Paola Galozzi, Paolo Sfriso, Carla Gaggiano, Salvatore Grosso, Donato Rigante, Lorenzo Dagna, Roberto Giacomelli, Luca Cantarini
Frontiers in Medicine, 2020 - The wide spectrum of Kawasaki-like disease associated with SARS-CoV-2 infection
Onorina Berardicurti, Alessandro Conforti, Piero Ruscitti, Paola Cipriani, Roberto Giacomelli
Expert Review of Clinical Immunology, 2020 - Efficacy and safety of imatinib mesylate in systemic sclerosis. A systematic review and meta-analysis
Vasiliki Liakouli, Jacopo Ciaffi, Francesco Ursini, Piero Ruscitti, Riccardo Meliconi, Francesco Ciccia, Paola Cipriani, Roberto Giacomelli
Expert Review of Clinical Immunology, 2020 - Prescribing motivations and patients’ characteristics related to the use of biologic drugs in adult-onset Still’s disease: analysis of a multicentre “real-life” cohort
Piero Ruscitti, Paola Cipriani, Vasiliki Liakouli, Daniela Iacono, Ilenia Pantano, Francesco Caso, Federico Perosa, Fabiola Atzeni, Francesco Paolo Cantatore, Raffaele Scarpa, Francesco Ciccia, Roberto Giacomelli
Rheumatology International, 2020 - Advanced diagnostic imaging and intervention in tendon diseases
Federico Bruno, Pierpaolo Palumbo, Francesco Arrigoni, Silvia Mariani, Giacomo Aringhieri, et al.
Acta Biomedica, 2020 - Epidermal Growth Factor Like-domain 7 and miR-126 are abnormally expressed in diffuse Systemic Sclerosis fibroblasts
Vasiliki Liakouli, Paola Cipriani, Paola Di Benedetto, Noemi Panzera, Piero Ruscitti, Ilenia Pantano, Onorina Berardicurti, Francesco Carubbi, Filomena Esteves, Georgia Mavria, Francesco Del Galdo, Roberto Giacomelli
Scientific Reports, 2019 - Mesenchymal stem cells of Systemic Sclerosis patients, derived from different sources, show a profibrotic microRNA profiling
Paola Di Benedetto, Noemi Panzera, Paola Cipriani, Valentina Mastroiaco, Alessandra Tessitore, Vasiliki Liakouli, Piero Ruscitti, Onorina Berardicurti, Francesco Carubbi, Giuliana Guggino, Andrea Bianchi, Antinisca Di Marco, Francesco Ciccia, Edoardo Alesse, Roberto Giacomelli
Scientific Reports, 2019 - Subclinical and clinical atherosclerosis in rheumatoid arthritis: Results from the 3-year, multicentre, prospective, observational GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) study
Piero Ruscitti, Paola Cipriani, Vasiliki Liakouli, Daniela Iacono, Ilenia Pantano, Domenico Paolo Emanuele Margiotta, Luca Navarini, Giulia Maria Destro Castaniti, Nicola Maruotti, Gerardo Di Scala, Licia Picciariello, Francesco Caso, Sara Bongiovanni, Rosa Daniela Grembiale, Fabiola Atzeni, Raffaele Scarpa, Federico Perosa, Giacomo Emmi, Francesco Paolo Cantatore, Giuliana Guggino, Antonella Afeltra, Francesco Ciccia, Roberto Giacomelli
Arthritis Research and Therapy, 2019 - Correction: Cyclophosphamide pulse regimen in the treatment of alveolitis in systemic sclerosis (Journal of Rheumatology (2002) 29 (731-736))
Roberto Giacomelli, Gabriele Valentini, Felice Salsano, Paola Cipriani, Paola Sambo, et al.
Journal of Rheumatology, 2019 - Hepatitis E infection in a patient with rheumatoid arthritis treated with leflunomide: A case report with emphasis on geoepidemiology
Francesco Carubbi, Giovanna Picchi, Salvatore Di Bartolomeo, Alessandra Ricciardi, Paola Cipriani, Laura Marola, Alessandro Grimaldi, Roberto Giacomelli
Medicine United States, 2019 - The vessels contribute to fibrosis in systemic sclerosis
Israel Medical Association Journal, 2019 - Vitamin D increases the production of IL-10 by regulatory T cells in patients with systemic sclerosis
Clinical and Experimental Rheumatology, 2019 - Managing Adult-onset Still’s disease: The effectiveness of high-dosage of corticosteroids as first-line treatment in inducing the clinical remission. Results from an observational study
Piero Ruscitti, Paola Cipriani, Vasiliki Liakouli, Giuliana Guggino, Francesco Carubbi, Onorina Berardicurti, Francesco Ciccia, Roberto Giacomelli
Medicine United States, 2019 - IL-1 inhibition improves insulin resistance and adipokines in rheumatoid arthritis patients with comorbid type 2 diabetes: An observational study
Piero Ruscitti, Francesco Ursini, Paola Cipriani, Marta Greco, Saverio Alvaro, Liakouli Vasiliki, Paola Di Benedetto, Francesco Carubbi, Onorina Berardicurti, Elio Gulletta, Giovambattista De Sarro, Roberto Giacomelli
Medicine United States, 2019 - Linking myofibroblast generation and microvascular alteration: The role of CD248 from pathogenesis to therapeutic target (Review)
Paola Di Benedetto, Piero Ruscitti, Vasiliki Liakouli, Francesco Del Galdo, Roberto Giacomelli, Paola Cipriani
Molecular Medicine Reports, 2019 - The kaleidoscope of neurological manifestations in primary Sjögren's syndrome
Clinical and Experimental Rheumatology, 2019 - Laboratory assessment of patients with suspected rheumatic musculoskeletal diseases: Challenges and pitfalls
Francesco Carubbi, Alessia Alunno, Paola Cipriani, Onelia Bistoni, Rosa Scipioni, Valiki Liakouli, Piero Ruscitti, Onorina Berardicurti, Salvatore Di Bartolomeo, Roberto Gerli, Roberto Giacomelli
Current Rheumatology Reviews, 2019 - Different operators and histologic techniques in the assessment of germinal center-like structures in primary Sjögren's syndrome minor salivary glands
Francesco Carubbi, Alessia Alunno, Paola Cipriani, Gino Coletti, Barbara Bigerna, Mirko Manetti, Paola Di Benedetto, Onelia Bistoni, Gianluca Cipolloni, Vasiliki Liakouli, Piero Ruscitti, Elena Bartoloni, Roberto Giacomelli, Roberto Gerli
Plos One, 2019 - Anti-interleukin-1 treatment in patients with rheumatoid arthritis and type 2 diabetes (TRACK): A multicentre, open-label, randomised controlled trial
Piero Ruscitti, Francesco Masedu, Saverio Alvaro, Paolo Airò, Norma Battafarano, Luca Cantarini, Francesco Paolo Cantatore, Giorgio Carlino, Virginia D'Abrosca, Micol Frassi, Bruno Frediani, Daniela Iacono, Vasiliki Liakouli, Roberta Maggio, Rita Mulè, Ilenia Pantano, Immacolata Prevete, Luigi Sinigaglia, Marco Valenti, Ombretta Viapiana, Paola Cipriani, Roberto Giacomelli
Plos Medicine, 2019 - Guidelines for biomarkers in autoimmune rheumatic diseases - evidence based analysis
Roberto Giacomelli, Antonella Afeltra, Alessia Alunno, Elena Bartoloni-Bocci, Onorina Berardicurti, Michele Bombardieri, Alessandra Bortoluzzi, Roberto Caporali, Francesco Caso, Ricard Cervera, Maria Sole Chimenti, Paola Cipriani, Emmanuel Coloma, Fabrizio Conti, Salvatore D’Angelo, Salvatore De Vita, Salvatore Di Bartolomeo, Oliver Distler, Andrea Doria, Eugen Feist, Benjamin A. Fisher, Maria Gerosa, Michele Gilio, Giuliana Guggino, Vasiliki Liakouli, Domenico Paolo Emanuele Margiotta, Pierluigi Meroni, Gianluca Moroncini, Federico Perosa, Marcella Prete, Roberta Priori, Chiara Rebuffi, Piero Ruscitti, Raffaele Scarpa, Yehuda Shoenfeld, Monica Todoerti, Francesco Ursini, Guido Valesini, Serena Vettori, Claudio Vitali, Athanasios G. Tzioufas
Autoimmunity Reviews, 2019 - Long-term retention rate of anakinra in adult onset Still’s disease and predictive factors for treatment response
Antonio Vitale, Giulio Cavalli, Serena Colafrancesco, Roberta Priori, Guido Valesini, Lorenza Maria Argolini, Elena Baldissera, Elena Bartoloni, Daniele Cammelli, Giovanni Canestrari, Jurgen Sota, Elena Cavallaro, Maria Grazia Massaro, Piero Ruscitti, Paola Cipriani, Ginevra De Marchi, Salvatore De Vita, Giacomo Emmi, Gianfranco Ferraccioli, Micol Frassi, Roberto Gerli, Elisa Gremese, Florenzo Iannone, Giovanni Lapadula, Giuseppe Lopalco, Raffaele Manna, Alessandro Mathieu, Carlomaurizio Montecucco, Marta Mosca, Ilaria Piazza, Matteo Piga, Irene Pontikaki, Micol Romano, Silvia Rossi, Maurizio Rossini, Elena Silvestri, Chiara Stagnaro, Rosaria Talarico, Angela Tincani, Ombretta Viapiana, Gianfranco Vitiello, Paola Galozzi, Paolo Sfriso, Carla Gaggiano, Donato Rigante, Lorenzo Dagna, Roberto Giacomelli, Luca Cantarini
Frontiers in Pharmacology, 2019 - Proinflammatory CX3CR1+CD59+Tumor Necrosis Factor–Like Molecule 1A+Interleukin-23+ Monocytes Are Expanded in Patients With Ankylosing Spondylitis and Modulate Innate Lymphoid Cell 3 Immune Functions
Francesco Ciccia, Giuliana Guggino, Michael Zeng, Ranjeny Thomas, Vidya Ranganathan, Arifur Rahman, Riccardo Alessandro, Aroldo Rizzo, Laura Saieva, Federica Macaluso, Sergio Peralta, Diana Di Liberto, Francesco Dieli, Paola Cipriani, Roberto Giacomelli, Dominique Baeten, Nigil Haroon
Arthritis and Rheumatology, 2018 - The role of extracellular matrix components in angiogenesis and fibrosis: Possible implication for Systemic Sclerosis
Vasiliki Liakouli, Paola Cipriani, Paola Di Benedetto, Piero Ruscitti, Francesco Carubbi, Onorina Berardicurti, Noemi Panzera, Roberto Giacomelli
Modern Rheumatology, 2018 - Downregulation of miRNA17-92 cluster marks Vγ9Vδ2 T cells from patients with rheumatoid arthritis
Giuliana Guggino, Valentina Orlando, Laura Saieva, Piero Ruscitti, Paola Cipriani, Marco Pio La Manna, Roberto Giacomelli, Riccardo Alessandro, Giovanni Triolo, Francesco Ciccia, Francesco Dieli, Nadia Caccamo
Arthritis Research and Therapy, 2018 - Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: A new potential target for antifibrotic therapy
Paola Di Benedetto, Vasiliki Liakouli, Piero Ruscitti, Onorina Berardicurti, Francesco Carubbi, Noemi Panzera, Salvatore Di Bartolomeo, Giuliana Guggino, Francesco Ciccia, Giovanni Triolo, Paola Cipriani, Roberto Giacomelli
Arthritis Research and Therapy, 2018 - Tailored approach to rheumatoid arthritis treatment with TNF inhibitors: where do we stand?
Roberto Caporali, Veronica Codullo, Paola Cipriani, Roberto Giacomelli
Rheumatology Oxford England, 2018 - Interleukin-25 Axis Is Involved in the Pathogenesis of Human Primary and Experimental Murine Sjögren's Syndrome
Giuliana Guggino, Xiang Lin, Aroldo Rizzo, Fan Xiao, Laura Saieva, Stefania Raimondo, Diana Di Liberto, Giuseppina Candore, Piero Ruscitti, Paola Cipriani, Roberto Giacomelli, Francesco Dieli, Riccardo Alessandro, Giovanni Triolo, Liwei Lu, Francesco Ciccia
Arthritis and Rheumatology, 2018 - Macrophage activation syndrome in patients affected by adult-onset still disease: Analysis of survival rates and predictive factors in the Gruppo Italiano di Ricerca in reumatologia clinica e sperimentale cohort
Piero Ruscitti, Daniela Iacono, Francesco Ciccia, Giacomo Emmi, Paola Cipriani, Rosa Daniela Grembiale, Federico Perosa, Lorenzo Emmi, Giovanni Triolo, Roberto Giacomelli, Gabriele Valentini
Journal of Rheumatology, 2018 - Scleroderma fibroblasts suppress angiogenesis via TGF-β/caveolin-1 dependent secretion of pigment epithelium-derived factor
Vasiliki Liakouli, Jacobo Elies, Yasser Mohamed El-Sherbiny, Margherita Scarcia, Gary Grant, Giuseppina Abignano, Emma C Derrett-Smith, Filomena Esteves, Paola Cipriani, Paul Emery, Christopher P Denton, Roberto Giacomelli, Georgia Mavria, Francesco Del Galdo
Annals of the Rheumatic Diseases, 2018 - Adipocytokines in rheumatoid arthritis: The hidden link between inflammation and cardiometabolic comorbidities
Piero Ruscitti, Paola Di Benedetto, Onorina Berardicurti, Vasiliki Liakouli, Francesco Carubbi, Paola Cipriani, Roberto Giacomelli
Journal of Immunology Research, 2018 - Cardiovascular disease in primary sjögren’s syndrome
Onorina Berardicurti, Piero Ruscitti, Paola Cipriani, Francesco Ciccia, Vasiliki Liakouli, Giuliana Guggino, Francesco Carubbi, Paola Di Benedetto, Giovanni Triolo, Roberto Giacomelli
Reviews on Recent Clinical Trials, 2018 - H-ferritin and proinflammatory cytokines are increased in the bone marrow of patients affected by macrophage activation syndrome
P Ruscitti, P Cipriani, P Di Benedetto, V Liakouli, O Berardicurti, F Carubbi, F Ciccia, G Guggino, G Triolo, R Giacomelli
Clinical and Experimental Immunology, 2018 - The emerging role of IL-1 inhibition in patients affected by rheumatoid arthritis and diabetes
Piero Ruscitti, Paola Cipriani, Vasiliky Liakouli, Francesco Carubbi, Onorina Berardicurti, Paola Di Benedetto, Francesco Ciccia, Giuliana Guggino, Saverio Alvaro, Giovanni Triolo, Roberto Giacomelli
Reviews on Recent Clinical Trials, 2018 - Macrophage activation syndrome in Still’s disease: analysis of clinical characteristics and survival in paediatric and adult patients
Piero Ruscitti, Carmela Rago, Luciana Breda, Paola Cipriani, Vasiliki Liakouli, Onorina Berardicurti, Francesco Carubbi, Caterina Di Battista, Alberto Verrotti, Roberto Giacomelli
Clinical Rheumatology, 2017 - PTP4A1 promotes TGFβ signaling and fibrosis in systemic sclerosis
Cristiano Sacchetti, Yunpeng Bai, Stephanie M. Stanford, Paola Di Benedetto, Paola Cipriani, Eugenio Santelli, Sonsoles Piera-Velazquez, Vladimir Chernitskiy, William B. Kiosses, Arnold Ceponis, Klaus H. Kaestner, Francesco Boin, Sergio A. Jimenez, Roberto Giacomelli, Zhong-Yin Zhang, Nunzio Bottini
Nature Communications, 2017 - Biologic drugs in adult onset Still’s disease: a systematic review and meta-analysis of observational studies
Piero Ruscitti, Francesco Ursini, Paola Cipriani, Giovambattista De Sarro, Roberto Giacomelli
Expert Review of Clinical Immunology, 2017 - Advances in immunopathogenesis of macrophage activation syndrome during rheumatic inflammatory diseases: toward new therapeutic targets?
Piero Ruscitti, Paola Cipriani, Paola Di Benedetto, Vasiliky Liakouli, Francesco Carubbi, Onorina Berardicurti, Francesco Ciccia, Giuliana Guggino, Giovanni Triolo, Roberto Giacomelli
Expert Review of Clinical Immunology, 2017 - Interleukin-9 over-expression and T helper 9 polarization in systemic sclerosis patients
G Guggino, M Lo Pizzo, D Di Liberto, A Rizzo, P Cipriani, P Ruscitti, G Candore, C M Gambino, G Sireci, F Dieli, R Giacomelli, G Triolo, F Ciccia
Clinical and Experimental Immunology, 2017 - Computed Tomography and MR Imaging in Rheumatoid Arthritis
Antonio Barile, Francesco Arrigoni, Federico Bruno, Giuseppe Guglielmi, Marcello Zappia, Alfonso Reginelli, Piero Ruscitti, Paola Cipriani, Roberto Giacomelli, Luca Brunese, Carlo Masciocchi
Radiologic Clinics of North America, 2017 - Pharmacological stress, rest perfusion and delayed enhancement cardiac magnetic resonance identifies very early cardiac involvement in systemic sclerosis patients of recent onset
Roberto Giacomelli, Ernesto Di Cesare, Paola Cipriani, Piero Ruscitti, Alessandra Di Sibio, Vasiliki Liakouli, Antonio Gennarelli, Francesco Carubbi, Alessandra Splendiani, Onorina Berardicurti, Paola Di Benedetto, Francesco Ciccia, Giuliana Guggino, Ganna Radchenko, Giovanni Triolo, Carlo Masciocchi
International Journal of Rheumatic Diseases, 2017 - International consensus: What else can we do to improve diagnosis and therapeutic strategies in patients affected by autoimmune rheumatic diseases (rheumatoid arthritis, spondyloarthritides, systemic sclerosis, systemic lupus erythematosus, antiphospholipid syndrome and Sjogren's syndrome)?: The unmet needs and the clinical grey zone in autoimmune disease management
Roberto Giacomelli, Antonella Afeltra, Alessia Alunno, Chiara Baldini, Elena Bartoloni-Bocci, Onorina Berardicurti, Francesco Carubbi, Alberto Cauli, Ricard Cervera, Francesco Ciccia, Paola Cipriani, Fabrizio Conti, Salvatore De Vita, Paola Di Benedetto, Andrea Doria, Alexandros A. Drosos, Ennio Giulio Favalli, Saviana Gandolfo, Mariele Gatto, Rosa Daniela Grembiale, Vasiliki Liakouli, Rik Lories, Ennio Lubrano, Claudio Lunardi, Domenico Paolo Emanuele Margiotta, Laura Massaro, Pierluigi Meroni, Antonia Minniti, Luca Navarini, Monica Pendolino, Federico Perosa, Jacques-Olivier Pers, Marcella Prete, Roberta Priori, Francesco Puppo, Luca Quartuccio, Amelia Ruffatti, Piero Ruscitti, Barbara Russo, Piercarlo Sarzi-Puttini, Yehuda Shoenfeld, George A. Somarakis, Francesca Romana Spinelli, Elisa Tinazzi, Giovanni Triolo, Francesco Ursini, Gabriele Valentini, Guido Valesini, Serena Vettori, Claudio Vitali, Athanasios G. Tzioufas
Autoimmunity Reviews, 2017 - Prevalence of type 2 diabetes and impaired fasting glucose in patients affected by rheumatoid arthritis
Piero Ruscitti, Francesco Ursini, Paola Cipriani, Francesco Ciccia, Vasiliki Liakouli, Francesco Carubbi, Giuliana Guggino, Onorina Berardicurti, Rosadaniela Grembiale, Giovanni Triolo, Giovambattista De Sarro, Roberto Giacomelli
Medicine United States, 2017 - Poor clinical response in rheumatoid arthritis is the main risk factor for diabetes development in the short-term: A 1-year, single-centre, longitudinal study
Piero Ruscitti, Francesco Ursini, Paola Cipriani, Vasiliki Liakouli, Francesco Carubbi, Onorina Berardicurti, Giovambattista De Sarro, Roberto Giacomelli
Plos One, 2017 - Response to interleukin-1 inhibitors in 140 Italian patients with adult-onset still's disease: A multicentre retrospective observational study
Serena Colafrancesco, Roberta Priori, Guido Valesini, Lorenza Argolini, Elena Baldissera, Elena Bartoloni, Daniele Cammelli, Giovanni Canestrari, Luca Cantarini, Elena Cavallaro, Giulio Cavalli, Lucia Cerrito, Paola Cipriani, Lorenzo Dagna, Ginevra De Marchi, Salvatore De Vita, Giacomo Emmi, Gianfranco Ferraccioli, Micol Frassi, Mauro Galeazzi, Roberto Gerli, Roberto Giacomelli, Elisa Gremese, Florenzo Iannone, Giovanni Lapadula, Giuseppe Lopalco, Raffaele Manna, Alessandro Mathieu, Carlomaurizio Montecucco, Marta Mosca, Ilaria Piazza, Matteo Piga, Irene Pontikaki, Micol Romano, Silvia Rossi, Maurizio Rossini, Piero Ruscitti, Elena Silvestri, Chiara Stagnaro, Rosaria Talarico, Angela Tincani, Ombretta Viapiana, Gianfranco Vitiello, Francesca Fabris, Sara Bindoli, Leonardo Punzi, Paola Galozzi, Paolo Sfriso
Frontiers in Pharmacology, 2017 - Interstitial lung disease in systemic sclerosis: current and future treatment
Roberto Giacomelli, Vasiliki Liakouli, Onorina Berardicurti, Piero Ruscitti, Paola Di Benedetto, Francesco Carubbi, Giuliana Guggino, Salvatore Di Bartolomeo, Francesco Ciccia, Giovanni Triolo, Paola Cipriani
Rheumatology International, 2017 - Biologic therapies and infections in the daily practice of three Italian rheumatologic units: a prospective, observational study
Paola Cipriani, Onorina Berardicurti, Francesco Masedu, Francesca D’Onofrio, Luca Navarini, Piero Ruscitti, Nicola Maruotti, Domenico Paolo Emanuele Margiotta, Vasiliki Liakouli, Paola Di Benedetto, Francesco Carubbi, Marco Valenti, Francesco Paolo Cantatore, Antonella Afeltra, Roberto Giacomelli
Clinical Rheumatology, 2017 - Phenotypical and functional characteristics of in vitro-expanded adipose-derived mesenchymal stromal cells from patients with systematic sclerosis
Chiara Capelli, Eleonora Zaccara, Paola Cipriani, Paola Di Benedetto, Wanda Maglione, Romina Andracco, Gabriele Di Luca, Francesca Pignataro, Roberto Giacomelli, Martino Introna, Claudio Vitali, Nicoletta Del Papa
Cell Transplantation, 2017 - Increased cardiovascular events and subclinical atherosclerosis in rheumatoid arthritis patients: 1 year prospective single centre study
Piero Ruscitti, Paola Cipriani, Francesco Masedu, Silvio Romano, Onorina Berardicurti, Vasiliki Liakouli, Francesco Carubbi, Paola Di Benedetto, Saverio Alvaro, Maria Penco, Marco Valenti, Roberto Giacomelli
Plos One, 2017 - Prognostic factors of macrophage activation syndrome, at the time of diagnosis, in adult patients affected by autoimmune disease: Analysis of 41 cases collected in 2 rheumatologic centers
Piero Ruscitti, Paola Cipriani, Francesco Ciccia, Francesco Masedu, Vasiliki Liakouli, Francesco Carubbi, Onorina Berardicurti, Giuliana Guggino, Paola Di Benedetto, Salvatore Di Bartolomeo, Marco Valenti, Giovanni Triolo, Roberto Giacomelli
Autoimmunity Reviews, 2017 - What could we learn from the sub-analysis of a single nation cohort in a worldwide study? Lessons from the results observed in the Italian cohort of the GO-MORE trial
Clinical and Experimental Rheumatology, 2017 - Interleukin (IL)-9/IL-9R axis drives γδ T cells activation in psoriatic arthritis patients
G Guggino, F Ciccia, D Di Liberto, M Lo Pizzo, P Ruscitti, P Cipriani, A Ferrante, G Sireci, F Dieli, J J Fourniè, R Giacomelli, G Triolo
Clinical and Experimental Immunology, 2016 - Adult-onset Still's disease: Evaluation of prognostic tools and validation of the systemic score by analysis of 100 cases from three centers
Piero Ruscitti, Paola Cipriani, Francesco Masedu, Daniela Iacono, Francesco Ciccia, Vasiliki Liakouli, Giuliana Guggino, Francesco Carubbi, Onorina Berardicurti, Paola Di Benedetto, Marco Valenti, Giovanni Triolo, Gabriele Valentini, Roberto Giacomelli
BMC Medicine, 2016 - Persistence of focal lymphocytic sialadenitis in patients with primary Sjögren's syndrome treated with rituximab: a possible role for glandular BAFF
Clinical and Experimental Rheumatology, 2016 - Endothelial progenitor cells: Are they displaying a function in autoimmune disorders?
Angelo Ferrante, Giuliana Guggino, Diana Di Liberto, Francesco Ciccia, Paola Cipriani, Carmela Rita Balistreri, Guido Sireci, Roberto Giacomelli, Giovanni Triolo
Mechanisms of Ageing and Development, 2016 - Mesenchymal Stem Cell Transplantation in Systemic Sclerosis: Comment on the Article by Maria et al
Paola Cipriani, Paola Di Benedetto, Vasiliki Liakouli, Roberto Giacomelli
Arthritis and Rheumatology, 2016 - IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone?
Roberto Giacomelli, Piero Ruscitti, Saverio Alvaro, Francesco Ciccia, Vasiliki Liakouli, Paola Di Benedetto, Giuliana Guggino, Onorina Berardicurti, Francesco Carubbi, Giovanni Triolo, Paola Cipriani
Expert Review of Clinical Immunology, 2016 - Interleukin-9 and T helper type 9 cells in rheumatic diseases
F Ciccia, G Guggino, A Ferrante, P Cipriani, R Giacomelli, G Triolo
Clinical and Experimental Immunology, 2016 - Searching for a good model for systemic sclerosis: The molecular profile and vascular changes occurring in UCD-200 chickens strongly resemble the early phase of human systemic sclerosis
Paola Cipriani, Paola Di Benedetto, Hermann Dietrich, Piero Ruscitti, Vasiliki Liakouli, Francesco Carubbi, Ilenia Pantano, Onorina Berardicurti, Roswitha Sgonc, Roberto Giacomelli
Archives of Medical Science, 2016 - Interleukin-9 Overexpression and Th9 Polarization Characterize the Inflamed Gut, the Synovial Tissue, and the Peripheral Blood of Patients With Psoriatic Arthritis
Francesco Ciccia, Giuliana Guggino, Angelo Ferrante, Stefania Raimondo, Rodolfo Bignone, Vito Rodolico, Sergio Peralta, Melissa Van Tok, Alessandra Cannizzaro, Claudia Schinocca, Piero Ruscitti, Paola Cipriani, Roberto Giacomelli, Riccardo Alessandro, Francesco Dieli, Aroldo Rizzo, Dominique Baeten, Giovanni Triolo
Arthritis and Rheumatology, 2016 - Perivascular cells in diffuse cutaneous systemic sclerosis overexpress activated ADAM12 and are involved in myofibroblast transdifferentiation and development of fibrosis
Paola Cipriani, Paola Di Benedetto, Piero Ruscitti, Vasiliki Liakouli, Onorina Berardicurti, Francesco Carubbi, Francesco Ciccia, Giuliana Guggino, Francesca Zazzeroni, Edoardo Alesse, Giovanni Triolo, Roberto Giacomelli
Journal of Rheumatology, 2016 - Novel Therapeutic Strategies in Sjögren's Syndrome: B-Cell Targeting
F. Carubbi, P. Cipriani, R. Giacomelli
Sjogren S Syndrome Novel Insights in Pathogenic Clinical and Therapeutic Aspects, 2016 - Interleukin (IL)-17-producing pathogenic T lymphocytes co-express CD20 and are depleted by rituximab in primary Sjögren's syndrome: A pilot study
A Alunno, F Carubbi, O Bistoni, S Caterbi, E Bartoloni, P Di Benedetto, P Cipriani, R Giacomelli, R Gerli
Clinical and Experimental Immunology, 2016 - Safety and efficacy of intra-articular anti-tumor necrosis factor α agents compared to corticosteroids in a treat-to-target strategy in patients with inflammatory arthritis and monoarthritis flare
Francesco Carubbi, Luigi Zugaro, Paola Cipriani, Armando Conchiglia, Lorenzo Gregori, Cristino Danniballe, Maria Letizia Pistoia, Vasiliki Liakouli, Piero Ruscitti, Francesco Ciccia, Giovanni Triolo, Carlo Masciocchi, Roberto Giacomelli
International Journal of Immunopathology and Pharmacology, 2016 - The CD68+/H-ferritin+ cells colonize the lymph nodes of the patients with adult onset Still's disease and are associated with increased extracellular level of H-ferritin in the same tissue: Correlation with disease severity and implication for pathogenesis
P Ruscitti, F Ciccia, P Cipriani, G Guggino, P Di Benedetto, A Rizzo, V Liakouli, O Berardicurti, F Carubbi, G Triolo, R Giacomelli
Clinical and Experimental Immunology, 2016 - Comment on 'Where are we going in the management of interstitial lung disease in patients with systemic sclerosis?'
Michele Iudici, Gianluca Moroncini, Paola Cipriani, Roberto Giacomelli, Armando Gabrielli, Gabriele Valentini
Autoimmunity Reviews, 2016 - H-ferritin and CD68+/H-ferritin+ monocytes/macrophages are increased in the skin of adult-onset Still's disease patients and correlate with the multi-visceral involvement of the disease
P Ruscitti, P Cipriani, F Ciccia, P Di Benedetto, V Liakouli, O Berardicurti, F Carubbi, G Guggino, S Di Bartolomeo, G Triolo, R Giacomelli
Clinical and Experimental Immunology, 2016 - Association of psoriasis and/or psoriatic arthritis with autoimmune diseases: The experience of two Italian integrated Dermatology/Rheumatology outpatient clinics
F. Carubbi, M.S. Chimenti, G. Blasetti, P. Cipriani, A. Musto, M.C. Fargnoli, R. Perricone, R. Giacomelli, K. Peris
Journal of the European Academy of Dermatology and Venereology, 2015 - Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1β via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3(NLRP3)-inflammasome activation: A possible implication for therapeutic decision in these patients
P Ruscitti, P Cipriani, P Di Benedetto, V Liakouli, O Berardicurti, F Carubbi, F Ciccia, S Alvaro, G Triolo, R Giacomelli
Clinical and Experimental Immunology, 2015 - The endothelial-mesenchymal transition in systemic sclerosis is induced by endothelin-1 and transforming growth factor-β and may be blocked by Macitentan, a dual endothelin-1 receptor antagonist
Paola Cipriani, Paola Di Benedetto, Piero Ruscitti, Daria Capece, Francesca Zazzeroni, Vasiliki Liakouli, Ilenia Pantano, Onorina Berardicurti, Francesco Carubbi, Gianluca Pecetti, Stefano Turricchia, Edoardo Alesse, Marc Iglarz, Roberto Giacomelli
Journal of Rheumatology, 2015 - Macitentan inhibits the transforming growth factor-β profibrotic action, blocking the signaling mediated by the ETR/TβRI complex in systemic sclerosis dermal fibroblasts
Paola Cipriani, Paola Di Benedetto, Piero Ruscitti, Daniela Verzella, Mariafausta Fischietti, Francesca Zazzeroni, Vasiliki Liakouli, Francesco Carubbi, Onorina Berardicurti, Edoardo Alesse, Roberto Giacomelli
Arthritis Research and Therapy, 2015 - Where are we going in the management of interstitial lung disease in patients with systemic sclerosis?
Michele Iudici, Gianluca Moroncini, Paola Cipriani, Roberto Giacomelli, Armando Gabrielli, Gabriele Valentini
Autoimmunity Reviews, 2015 - Efficacy of inhibition of IL-1 in patients with rheumatoid arthritis and type 2 diabetes mellitus: Two case reports and review of the literature
Piero Ruscitti, Paola Cipriani, Luca Cantarini, Vasiliki Liakouli, Antonio Vitale, Francesco Carubbi, Onorina Berardicurti, Mauro Galeazzi, Marco Valenti, Roberto Giacomelli
Journal of Medical Case Reports, 2015 - Increased level of H-ferritin and its imbalance with L-ferritin, in bone marrow and liver of patients with adult onset Still's disease, developing macrophage activation syndrome, correlate with the severity of the disease
Piero Ruscitti, Paola Cipriani, Paola Di Benedetto, Francesco Ciccia, Vasiliki Liakouli, Francesco Carubbi, Onorina Berardicurti, Aroldo Rizzo, Giovanni Triolo, Roberto Giacomelli
Autoimmunity Reviews, 2015 - A retrospective, multicenter study evaluating the prognostic value of minor salivary gland histology in a large cohort of patients with primary Sjögren's syndrome
F Carubbi, A Alunno, P Cipriani, E Bartoloni, C Baldini, L Quartuccio, R Priori, G Valesini, S De Vita, S Bombardieri, R Gerli, R Giacomelli
Lupus, 2015 - Stem cell therapies for systemic sclerosis
Paola Cipriani, Piero Ruscitti, Roberto Giacomelli
British Journal of Haematology, 2015 - The role of IL-1β in the bone loss during rheumatic diseases
Piero Ruscitti, Paola Cipriani, Francesco Carubbi, Vasiliki Liakouli, Francesca Zazzeroni, Paola Di Benedetto, Onorina Berardicurti, Edoardo Alesse, Roberto Giacomelli
Mediators of Inflammation, 2015 - Mesenchymal stromal cells and rheumatic diseases: New tools from pathogenesis to regenerative therapies
Paola Cipriani, Piero Ruscitti, Paola Di Benedetto, Francesco Carubbi, Vasiliki Liakouli, Onorina Berardicurti, Francesco Ciccia, Giovanni Triolo, Roberto Giacomelli
Cytotherapy, 2015 - T regulatory and T helper 17 cells in primary Sjögren's syndrome: Facts and perspectives
Alessia Alunno, Francesco Carubbi, Onelia Bistoni, Sara Caterbi, Elena Bartoloni, Giulia Mirabelli, Francesca Cannarile, Paola Cipriani, Roberto Giacomelli, Roberto Gerli
Mediators of Inflammation, 2015 - Erratum to Is minor salivary gland biopsy more than a diagnostic tool in primary Sjorgren's syndrome? Association between clinical, histopathological, and molecular features: A retrospective study [Semin Arthritis Rheum, 44, (2014), 314-324] Doi: 10.1016/j.semarthrit.2014.05.015
Francesco Carubbi, Alessia Alunno, Paola Cipriani, Paola Di Benedetto, Piero Ruscitti, Onorina Berardicurti, Elena Bartoloni, Onelia Bistoni, Sara Caterbi, Francesco Ciccia, Giovanni Triolo, Roberto Gerli, Roberto Giacomelli
Seminars in Arthritis and Rheumatism, 2015 - Interleukin (IL)-22 receptor 1 is over-expressed in primary Sjogren's syndrome and Sjögren-associated non-Hodgkin lymphomas and is regulated by IL-18
F Ciccia, G Guggino, A Rizzo, M Bombardieri, S Raimondo, F Carubbi, A Cannizzaro, G Sireci, F Dieli, G Campisi, R Giacomelli, Paola Cipriani, G De Leo, R Alessandro, G Triolo
Clinical and Experimental Immunology, 2015 - Myositis in primary Sjögren's syndrome: Data from a multicentre cohort
Clinical and Experimental Rheumatology, 2015 - Unmasking the pathogenic role of IL-17 axis in primary Sjögren's syndrome: A new era for therapeutic targeting?
Alessia Alunno, Francesco Carubbi, Elena Bartoloni, Onelia Bistoni, Sara Caterbi, Paola Cipriani, Roberto Giacomelli, Roberto Gerli
Autoimmunity Reviews, 2014 - Is minor salivary gland biopsy more than a diagnostic tool in primary Sjorgren's syndrome? Association between clinical, histopathological, and molecular features: A retrospective study
Francesco Carubbi, Alessia Alunno, Paola Cipriani, Paola Di Benedetto, Piero Ruscitti, Onorina Berardicurti, Elena Bartoloni, Onelia Bistoni, Sara Caterbi, Francesco Ciccia, Giovanni Triolo, Roberto Gerli, Roberto Giacomelli
Seminars in Arthritis and Rheumatism, 2014 - Rituximab in primary Sjögren's syndrome: A ten-year journey
F Carubbi, A Alunno, P Cipriani, E Bartoloni, F Ciccia, G Triolo, R Gerli, R Giacomelli
Lupus, 2014 - Methotrexate: An old new drug in autoimmune disease
Paola Cipriani, Piero Ruscitti, Francesco Carubbi, Vasiliki Liakouli, Roberto Giacomelli
Expert Review of Clinical Immunology, 2014 - Impaired Cav-1 expression in SSc mesenchymal cells upregulates VEGF signaling: A link between vascular involvement and fibrosis
Paola Cipriani, Paola Di Benedetto, Daria Capece, Francesca Zazzeroni, Vasiliki Liakouli, Piero Ruscitti, Ilenia Pantano, Onorina Berardicurti, Francesco Carubbi, Edoardo Alesse, Roberto Giacomelli
Fibrogenesis and Tissue Repair, 2014 - Methotrexate in rheumatoid arthritis: Optimizing therapy among different formulations. Current and emerging paradigms
Paola Cipriani, Piero Ruscitti, Francesco Carubbi, Vasiliki Liakouli, Roberto Giacomelli
Clinical Therapeutics, 2014 - Potential of stem cells in the treatment of rheumatic disease
Roberto Giacomelli, Piero Ruscitti, Paola Di Benedetto, Vasiliki Liakouli, Francesco Carubbi, Paola Cipriani
International Journal of Clinical Rheumatology, 2014 - Tocilizumab for the treatment of adult-onset Still's disease: Results from a case series
Paola Cipriani, Piero Ruscitti, Francesco Carubbi, Ilenia Pantano, Vasiliki Liakouli, Onorina Berardicurti, Roberto Giacomelli
Clinical Rheumatology, 2014 - Impaired endothelium-mesenchymal stem cells cross-talk in systemic sclerosis: A link between vascular and fibrotic features
Paola Cipriani, Paola Di Benedetto, Piero Ruscitti, Antonio Francesco Campese, Vasiliki Liakouli, Francesco Carubbi, Ilenia Pantano, Onorina Berardicurt, Isabella Screpanti, Roberto Giacomelli
Arthritis Research and Therapy, 2014 - Rituximab modulates IL-17 expression in the salivary glands of patients with primary Sjögren's syndrome
Francesco Ciccia, Giuliana Guggino, Aroldo Rizzo, Riccardo Alessandro, Francesco Carubbi, AnnaRita Giardina, Paola Cipriani, Angelo Ferrante, Alessandra Cannizzaro, Roberto Giacomelli, Giovanni Triolo
Rheumatology United Kingdom, 2014 - CD4-CD8- T-cells in primary Sjögren's syndrome: Association with the extent of glandular involvement
Alessia Alunno, Francesco Carubbi, Onelia Bistoni, Sara Caterbi, Elena Bartoloni, Barbara Bigerna, Roberta Pacini, Daniela Beghelli, Paola Cipriani, Roberto Giacomelli, Roberto Gerli
Journal of Autoimmunity, 2014 - Interstitial lung disease in systemic sclerosis: Pathophysiology and therapy
Scleroderma Symptoms Diagnosis and Treatment, 2013 - Efficacy and safety of rituximab treatment in early primary Sjögren's syndrome: A prospective, multi-center, follow-up study
Francesco Carubbi, Paola Cipriani, Alessandra Marrelli, Paola Di Benedetto, Piero Ruscitti, Onorina Berardicurti, Ilenia Pantano, Vasiliki Liakouli, Saverio Alvaro, Alessia Alunno, Antonio Manzo, Francesco Ciccia, Roberto Gerli, Giovanni Triolo, Roberto Giacomelli
Arthritis Research and Therapy, 2013 - Mesenchymal stem cells (MSCs) from scleroderma patients (SSc) preserve their immunomodulatory properties although senescent and normally induce T regulatory cells (Tregs) with a functional phenotype: Implications for cellular-based therapy
P Cipriani, P Di Benedetto, V Liakouli, B Del Papa, M Di Padova, M Di Ianni, A Marrelli, E Alesse, R Giacomelli
Clinical and Experimental Immunology, 2013 - Scleroderma Mesenchymal Stem Cells display a different phenotype from healthy controls; Implications for regenerative medicine
Paola Cipriani, Alessandra Marrelli, Paola Di Benedetto, Vasiliki Liakouli, Francesco Carubbi, Piero Ruscitti, Saverio Alvaro, Ilenia Pantano, Antonio Francesco Campese, Paola Grazioli, Isabella Screpanti, Roberto Giacomelli
Angiogenesis, 2013 - Early assessment of sub-clinical cardiac involvement in systemic sclerosis (SSc) using delayed enhancement cardiac magnetic resonance (CE-MRI)
Ernesto Di Cesare, Sara Battisti, Alessandra Di Sibio, Paola Cipriani, Roberto Giacomelli, Vasiliky Liakouli, Piero Ruscitti, Carlo Masciocchi
European Journal of Radiology, 2013 - Rituximab modulates the expression of IL-22 in the salivary glands of patients with primary Sjogren's syndrome
Francesco Ciccia, AnnaRita Giardina, Aroldo Rizzo, Giuliana Guggino, Paola Cipriani, Francesco Carubbi, Roberto Giacomelli, Giovanni Triolo
Annals of the Rheumatic Diseases, 2013 - Stem cells in autoimmune diseases: Implications for pathogenesis and future trends in therapy
Paola Cipriani, Francesco Carubbi, Vasiliki Liakouli, Alessandra Marrelli, Carlo Perricone, Roberto Perricone, Edoardo Alesse, Roberto Giacomelli
Autoimmunity Reviews, 2013 - Jejunoileal bypass as the main procedure in the onset of immune-related conditions: The model of BADAS
Francesco Carubbi, Piero Ruscitti, Ilenia Pantano, Saverio Alvaro, Paola Di Benedetto, Vasiliki Liakouli, Antonio Giuliani, Federica Piccione, Francesco Ciccia, Gianfranco Amicucci, Giovanni Triolo, Roberto Giacomelli, Paola Cipriani
Expert Review of Clinical Immunology, 2013 - Immunomodulation in psoriatic arthritis: Focus on cellular and molecular pathways
Maria Sole Chimenti, Eleonora Ballanti, Carlo Perricone, Paola Cipriani, Roberto Giacomelli, Roberto Perricone
Autoimmunity Reviews, 2013 - Long-term anti-TNF therapy and the risk of serious infections in a cohort of patients with rheumatoid arthritis: Comparison of adalimumab, etanercept and infliximab in the GISEA registry
Fabiola Atzeni, Piercarlo Sarzi-Puttini, Costantino Botsios, Antonio Carletto, Paola Cipriani, Ennio Giulio Favalli, Elena Frati, Valentina Foschi, Stefania Gasparini, AnnaRita Giardina, Elisa Gremese, Florenzo Iannone, Marco Sebastiani, Tamara Ziglioli, Domenico Biasi, Clodoveo Ferri, Mauro Galeazzi, Roberto Gerli, Roberto Giacomelli, Roberto Gorla, Marcello Govoni, Giovanni Lapadula, Antonio Marchesoni, Fausto Salaffi, Leonardo Punzi, Giovanni Triolo, Gianfranco Ferraccioli
Autoimmunity Reviews, 2012 - Longterm retention of tumor necrosis factor-α inhibitor therapy in a large Italian cohort of patients with rheumatoid arthritis from the GISEA Registry: An appraisal of predictors
FLORENZO IANNONE, ELISA GREMESE, FABIOLA ATZENI, DOMENICO BIASI, COSTANTINO BOTSIOS, PAOLA CIPRIANI, CLODOVEO FERRI, VALENTINA FOSCHI, MAURO GALEAZZI, ROBERTO GERLI, ANNARITA GIARDINA, ANTONIO MARCHESONI, FAUSTO SALAFFI, TAMARA ZIGLIOLI, GIOVANNI LAPADULA, Gruppo Italiano di Studio sulle Early Arthritides (GISEA)
Journal of Rheumatology, 2012 - Cellular players in angiogenesis during the course of systemic sclerosis
Paola Cipriani, Alessandra Marrelli, Vasiliki Liakouli, Paola Di Benedetto, Roberto Giacomelli
Autoimmunity Reviews, 2011 - Angiogenic cytokines and growth factors in systemic sclerosis
Vasiliki Liakouli, Paola Cipriani, Alessandra Marrelli, Saverio Alvaro, Piero Ruscitti, Roberto Giacomelli
Autoimmunity Reviews, 2011 - Angiogenesis in rheumatoid arthritis: A disease specific process or a common response to chronic inflammation?
Alessandra Marrelli, Paola Cipriani, Vasiliki Liakouli, Francesco Carubbi, Carlo Perricone, Roberto Perricone, Roberto Giacomelli
Autoimmunity Reviews, 2011 - Inhibition of the complement system by glutathione: Molecular mechanisms and potential therapeutic implications
C. Perricone, C. De Carolis, R. Giacomelli, E. Greco, P. Cipriani, E. Ballanti, L. Novelli, R. Perricone
International Journal of Immunopathology and Pharmacology, 2011 - Complement system and rheumatoid arthritis: Relationships with autoantibodies, serological, clinical features, and anti-TNF treatment
G. Di Muzio, C. Perricone, E. Ballanti, B. Kroegler, E. Greco, L. Novelli, P. Conigliaro, P. Cipriani, R. Giacomelli, R. Perricone
International Journal of Immunopathology and Pharmacology, 2011 - A genetic variation located in the promoter region of the UPAR (CD87) gene is associated with the vascular complications of systemic sclerosis
Mirko Manetti, Yannick Allanore, Lucile Revillod, Cinzia Fatini, Serena Guiducci, Giovanna Cuomo, Claudia Bonino, Valeria Riccieri, Laura Bazzichi, Vasiliki Liakouli, Paola Cipriani, Roberto Giacomelli, Rosanna Abbate, Stefano Bombardieri, Guido Valesini, Carlomaurizio Montecucco, Gabriele Valentini, Lidia Ibba‐Manneschi, Marco Matucci‐Cerinic
Arthritis and Rheumatism, 2011 - The IL1-like cytokine IL33 and its receptor ST2 are abnormally expressed in the affected skin and visceral organs of patients with systemic sclerosis
Mirko Manetti, Lidia Ibba-Manneschi, Vasiliki Liakouli, Serena Guiducci, Anna Franca Milia, Gemma Benelli, Alessandra Marrelli, Maria Letizia Conforti, Eloisa Romano, Roberto Giacomelli, Marco Matucci-Cerinic, Paola Cipriani
Annals of the Rheumatic Diseases, 2010 - The 2670g>a polymorphism in the FAS gene promoter region influences the susceptibility to systemic sclerosis
V Liakouli, M Manetti, A Pacini, B Tolusso, C Fatini, A Toscano, P Cipriani, S Guiducci, L Bazzichi, V Codullo, L Ruocco, L Dell’Orso, F Carubbi, A Marrelli, R Abbate, S Bombardieri, G Ferraccioli, C Montecucco, G Valentini, M Matucci-Cerinic, L Ibba-Manneschi, R Giacomelli
Annals of the Rheumatic Diseases, 2009 - Association between a stromal cell-derived factor 1 (SDF-1/CXCL12) gene polymorphism and microvascular disease in systemic sclerosis
M Manetti, V Liakouli, C Fatini, P Cipriani, C Bonino, S Vettori, S Guiducci, C Montecucco, R Abbate, G Valentini, M Matucci-Cerinic, R Giacomelli, L Ibba-Manneschi
Annals of the Rheumatic Diseases, 2009 - Comment on: Intravenous immunoglobulin therapy in pregnant patients affected with systemic lupus erythematosus and recurrent spontaneous abortion: Reply
R. Perricone, C. De Carolis, B. Kroegler, E. Greco, R. Giacomelli, P. Cipriani, L. Fontana, C. Perricone
Rheumatology, 2008 - Intravenous immunoglobulin therapy in pregnant patients affected with systemic lupus erythematosus and recurrent spontaneous abortion
R. Perricone, C. De Carolis, B. Kroegler, E. Greco, R. Giacomelli, P. Cipriani, L. Fontana, C. Perricone
Rheumatology, 2008 - High levels of NK cells in the peripheral blood of patients affected with anti-phospholipid syndrome and recurrent spontaneous abortion: A potential new hypothesis
C. Perricone, C. De Carolis, R. Giacomelli, G. Zaccari, P. Cipriani, E. Bizzi, R. Perricone
Rheumatology, 2007 - Impairment of endothelial cell differentiation from bone marrow-derived mesenchymal stem cells: New insight into the pathogenesis of systemic sclerosis
P. Cipriani, S. Guiducci, I. Miniati, M. Cinelli, S. Urbani, A. Marrelli, V. Dolo, A. Pavan, R. Saccardi, A. Tyndall, R. Giacomelli, M. Matucci Cerinic
Arthritis and Rheumatism, 2007 - Surface expression of fractalkine receptor (CX3CR1) on CD4+/CD28- T cells in RA patients and correlation with atherosclerotic damage
ELISA PINGIOTTI, PAOLA CIPRIANI, ALESSANDRA MARRELLI, VASILIKI LIAKOULI, SIMONA FRATINI, MARIA PENCO, ROBERTO GIACOMELLI
Annals of the New York Academy of Sciences, 2007 - Resistance to apoptosis in circulating α/β and γ/δ T lymphocytes from patients with systemic sclerosis
Journal of Rheumatology, 2006 - Differential expression of stromal cell-derived factor 1 and its receptor CXCR4 in the skin and endothelial cells of systemic sclerosis patients: Pathogenetic implications
Paola Cipriani, Anna Franca Milia, Vasiliki Liakouli, Alessandra Pacini, Mirko Manetti, Alessandra Marrelli, Annarita Toscano, Elisa Pingiotti, Antonietta Fulminis, Serena Guiducci, Roberto Perricone, Bashar Kahaleh, Marco Matucci‐Cerinic, Lidia Ibba‐Manneschi, Roberto Giacomelli
Arthritis and Rheumatism, 2006 - Variations of neuronal nitric oxide synthase in systemic sclerosis skin
Lidia Ibba‐Manneschi, Sirkku Niissalo, Anna Franca Milia, Yannick Allanore, Angela Del Rosso, Alessandra Pacini, Mirko Manetti, Annarita Toscano, Paola Cipriani, Vasiliki Liakouli, Roberto Giacomelli, André Kahan, Yrjö T. Konttinen, Marco Matucci‐Cerinic
Arthritis and Rheumatism, 2006 - γ/δ T cells in placenta and skin: Their different functions may support the paradigm of microchimerism in systemic sclerosis
Clinical and Experimental Rheumatology, 2004 - Combination therapy with cyclosporine and methotrexate in patients with early rheumatoid arthritis soon inhibits TNFα production without decreasing TNFα mRNA levels. An in vivo and in vitro study
Clinical and Experimental Rheumatology, 2002 - Cyclophosphamide pulse regimen in the treatment of alveolitis in systemic sclerosis
Journal of Rheumatology, 2002 - Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers
Oliver Distler, Angela del Rosso, Roberto Giacomelli, Paola Cipriani, Maria L Conforti, Serena Guiducci, Renate E Gay, Beat A Michel, Pius Brühlmann, Ulf Müller-Ladner, Steffen Gay, Marco Matucci-Cerinic
Arthritis Research, 2002 - Circulating γ/δ T lymphocytes from systemic sclerosis (SSc) patients display a T helper (Th) 1 polarization
R Giacomelli, P Cipriani, A Fulminis, G Barattelli, M Matucci-Cerinic, S D'Alò, G Cifone, G Tonietti
Clinical and Experimental Immunology, 2001 - Nerve growth factor and neuropeptides circulating levels in systemic sclerosis (scleroderma)
M Matucci-Cerinic, R Giacomelli, A Pignone, M L Cagnoni, S Generini, R Casale, P Cipriani, A Del Rosso, P Tirassa, Y T Konttinen, B M Kahaleh, P-S Fan, M Paoletti, C Marchesi, M Cagnoni, L Aloe
Annals of the Rheumatic Diseases, 2001 - Serum levels of soluble CD30 are increased in ulcerative colitis (UC) bug not in Crohn's disease (CD)
R Giacomelli, A Passacantando, I Parzanese, P Vernia, N Klidara, F Cucinelli, R Lattanzio, E Santori, P Cipriani, R Caprilli, G Tonietti
Clinical and Experimental Immunology, 1998 - Circulating Vδ1 + T cells are activated and accumulate in the skin of systemic sclerosis patients
R. Giacomelli, M. Matucci-Cerinic, P. Cipriani, I. Ghersetich, R. Lattanzio, A. Pavan, A. Pignone, M. L. Cagnoni, T. Lotti, G. Tonietti
Arthritis and Rheumatism, 1998 - Circulating levels of soluble CD30 are increased in patients with systemic sclerosis (SSc) and correlate with serological and clinical features of the disease
R GIACOMELLI, P CIPRIANI, R LATTANZIO, M DI FRANCO, M LOCANTO, I PARZANESE, A PASSACANTANDO, A CIOCCI, G TONIETTI
Clinical and Experimental Immunology, 1997 - γ/δ T cells are not involved in the natural and antibody-dependent cytotoxicity of peripheral blood mononuclear cells in inflammatory bowel disease
R. Giacomelli, A. Passacantando, I. Parzanese, F. Cucinelli, N. Klidara, R. Lattanzio, E. Santori, F. Paolini, L.L. Manetti, S. D'Alo, P. Cipriani, M.G. Cifone, G. Tonietti
International Journal of Immunopathology and Pharmacology, 1997 - Peripheral blood mononuclear cells of patients with systemic sclerosis produce increased amounts of interleukin 6, but not transforming growth factor β1
Journal of Rheumatology, 1996 - Increase of circulating γ/δ T lymphocytes in the peripheral blood of patients affected by active inflammatory bowel disease
R GIACOMELLI, I PARZANESE, G FRIERI, A PASSACANTANDO, F PIZZUTO, T PIMPO, P CIPRIANI, A VISCIDO, R CAPRILLI, G TONIETTI
Clinical and Experimental Immunology, 1994 - Clinical evaluation of efficaciousness and compliance of heparansulfphate in peripheral lower limbs arteriopathies
Rassegna Internazionale Di Clinica E Terapia, 1992
