Long-term results of the use of lyophilized xenodermoimplants in the surgical treatment of patients with cicatricial stenosis of the larynx P.V. Kovalyk, A.I. Yashan, A.P. Kovalyk Vestnik Otorinolaringologii, 2021 Purpose is to study the long-term results of patients with cicatricial stenosis of the larynx treated with use lyophilized xenodermoimplants for postoperative wound plasty. MATERIAL AND METHODS The results of treatment of 34 patients (age from 32 to 56 years) with cicatricial stenosis of the larynx were analyzed. A fundamentally new method of surgical treatment of such patients has been developed and introduced into practice, in which lyophilized xenodermoimplants were used for plasty of the wound surface. RESULTS The proposed technique made it possible in the immediate postoperative period to obtain a good result in 28 (82.4%) patients, satisfactory - in 6 (17.6%). The length of hospital stay was reduced by 8-10 days. In the long-term period (after 6-11 years), 27 patients were examined. Of these, 21 (77.8%) obtained a good result, and 6 (22.2%) - satisfactory. CONCLUSION The proposed method of surgical rehabilitation of the respiratory function of the larynx with its cicatricial stenosis using lyophilized xenodermoimplants is quite effective and can be proposed for use in clinical practice.
Microflora of laryngeal mucosa in the healthy subjects and the patients presenting with non-specific post-intubation laryngeal granuloma A. P. Kovalik Vestnik Otorinolaringologii, 2015 This comparative study was designed to determine the qualitative and quantitative composition of microflora of laryngeal mucosa in the healthy subjects and the patients presenting with non-specific post-intubation laryngeal granuloma. The secondary objective was to measure the sensitivity of the isolated microorganisms to antibiotic therapy. The quantitative characteristic and the species composition of the microbial associations in laryngeal mucosa were investigated in 40 healthy subjects and 72 patients presenting with non-specific post-intubation laryngeal granuloma. The mean age of the participants of the study varied from 31 to 69 years. The total microbial population density in the healthy subjects was 2.672±614 CFU/ml compared with 21.514±2.382 CFU/ml in the patients. The healthy subjects were found to carry streptococci in 87.5% of the cases, staphylococci and neisseria in 60.0% and 42.5% of the cases respectively. As many as 77.8%, 83.3%, and 90.3% of the patients with non-specific post-intubation laryngeal granuloma were carriers of these microorganism respectively. The dominant microorganisms in the mucous membrane of the larynx in these patients were N. flavescence (17.6%), S. aureus (9.01%), S. pneumonia (7.3%), and S. pyogenes (6.0%).The staphylococci isolated from the mucous membrane of the larynx of the patients presenting with non-specific post-intubation laryngeal granuloma exhibited the highest sensitivity to cephalosporin antibiotics (cefuroxime, cefprome or ceftriaxone) and fluoroquinolone (levofloxacin) antibiotics (100, 100, 91.7 and 96.7% respectively).
Characteristics of microflora of laryngeal mucosa in healthy subjects and patients with cicatrical stenosis of the larynx Vestnik Otorinolaringologii, 2010
Late complications of adenotomy Vestnik Oto Rino Laringologii, 2002
Complications in adenoidectomy and immediately after it Vestnik Oto Rino Laringologii, 2001
Ultracaine anesthesia in submucous resection of the nasal septum Vestnik Oto Rino Laringologii, 2001