Bridging the Gap: Baló Concentric Sclerosis-Like Leukoencephalopathy in Chronic Cocaine Use: A 1-Year Clinical and Imaging Follow-Up of 2 Cases Maria Lanzante, Alfonso Cerase, Anna de Mauro, Azzurra Forti, Paola Gullino, Francesco Sicurelli, Maria Laura Stromillo, Ivano Chiarotti, Sergio Antonio Tripodi, Nicola De Stefano, Carla Battisti, Rosa Cortese Neurology, 2026 Cocaine use is occasionally associated with development of acute leukoencephalopathy but only rarely do the magnetic resonance imaging (MRI) features resemble Baló concentric sclerosis, a demyelinating disorder traditionally considered within the multiple sclerosis spectrum. Here, we report 2 patients with history of cocaine use living in the same geographic area who were referred for acute multifocal leukoencephalopathy with a Baló-like pattern.Patient 1, a 31-year-old woman originally from the Philippines with chronic cocaine use history, presented with 1 week of rapidly worsening nonfluent aphasia, neglect, severe right hemiparesis, and numbness on the same side. Two months later, patient 2, a 25-year-old man originally from Morocco with chronic cocaine use history, presented with acute left leg weakness, confusion, and neglect. In both patients, brain MRI revealed multiple T2-hyperintense rounded lesions in the white matter, characterized by a concentric target-like appearance and gadolinium-enhanced incomplete ring pattern. In patient 1, a stereotactic biopsy confirmed a demyelinating inflammatory process with microcystic degeneration, increased cellularity, and macrophage/CD4+ lymphocyte infiltration. Both patients were treated with high-dose IV corticosteroid, resulting in significant clinical and radiologic improvement sustained at 1-year follow-up. Although corticosteroids yield promising outcomes, long-term prognosis hinges on sustained treatment adherence and abstinence from cocaine.The temporal and geographic proximity of these cases, occurring within 2 months in the same Italian province (covering an area of approximately 70 miles), raises the possibility of a shared toxic exposure which might explain the unique pathology and provide clues to the immune mechanisms that drive Baló-like demyelination.
Abuse in individuals with multiple sclerosis: the SocialMS Italian study Marta Ponzano, Alessio Signori, Irene Schiavetti, Doriana Landi, Andrea Bellavia, Luigi Lavorgna, Roberta Fantozzi, Fabio Buttari, Alessia Di Sapio, Simona Malucchi, Fabiana Marinelli, Mario Alberto Battaglia, Marco Vercellino, Graziella Callari, Jessica Frau, Girolama Alessandra Marfia, Elena Tsantes, Maria Grazia Grasso, Andrea Surcinelli, Luigi Zuliani, Cinzia Cordioli, Leonardo Sinisi, Raffaella Clerici, Paolo Immovilli, Maria Laura Stromillo, Laura Mori, Alice Laroni, Roberta Lanzillo, Alessandra Lugaresi, Maria Pia Sormani Multiple Sclerosis and Related Disorders, 2026
Serum peripherin as a disease biomarker in hereditary transthyretin amyloidosis: a multicenter cohort study Domenico Plantone, Delia Righi, Angela Romano, Luca Leonardi, Valeria Guglielmino, Francesca Forcina, Marco Ceccanti, Maurizio Inghilleri, Fiore Manganelli, Stefano Tozza, Maria Ausilia Sciarrone, Francesca Vitali, Andrea Sabino, Carlo Manco, Angela Stufano, Maria Laura Stromillo, Nicola De Stefano, Paolo Calabresi, Guido Primiano, Marco Luigetti Amyloid, 2026 Background Hereditary transthyretin amyloidosis (ATTRv, v for variant) is a rare, progressive, and fatal multisystemic disease. Peripherin represents a promising biomarker for axonal damage in the peripheral nervous system (PNS). This study aims to investigate serum peripherin levels in symptomatic and presymptomatic ATTRv subjects, alongside serum neurofilament light chain (sNfL) levels, and their correlations with disease progression and severity.Methods This multicenter, cross-sectional cohort study included 96 individuals with TTR gene variants (49 presymptomatic and 47 symptomatic ATTRv subjects) and 42 healthy controls (HCs). Serum peripherin levels were measured using a highly sensitive homebrew immunoassay, whereas sNfL levels were determined using a commercially available Simoa Neurology 2-Plex B assay. Statistical analyses included non-parametric Spearman correlations, Kruskal-Wallis ANOVA, ANCOVA, and binomial logistic regression.Results Serum peripherin levels were elevated in both presymptomatic (p < 0.001) and symptomatic ATTRv groups (p < 0.001) compared to HCs. Peripherin levels did not correlate with age, sNfL levels, or clinical severity, but showed a strong discriminative ability between ATTRv and HCs (AUC = 0.83, sensitivity = 76%, specificity = 76%, p < 0.001).Conclusions This study demonstrates that serum peripherin represents a promising biomarker for early detection of PNS damage in ATTRv, with elevated levels detectable even in presymptomatic stages.
Neurophysiological, imaging and neurobiological markers of central fatigue in multiple sclerosis Alberto Benelli, Elisa Tatti, Rosa Cortese, Elisa Massucco, Ludovico Luchetti, Marco Battaglini, Javier Cudeiro, Anna de Mauro, Jian Zhang, Domenico Plantone, Patrizio Pasqualetti, Delia Righi, Francesco Neri, Maria Laura Stromillo, Alessandra Cinti, Alessandro Giannotta, Francesco Lomi, Adriano Scoccia, Giuseppe Lai, Nicola De Stefano, Monica Ulivelli, Simone Rossi Brain Communications, 2026 Central fatigue affects 80% of patients with multiple sclerosis, with 60% of them claiming it as the most disabling symptom. Current research often independently explores neurophysiological, structural, or functional imaging and biological underpinnings of fatigue, thus lacking a multidimensional perspective. Here, we used a multidimensional approach to investigate the functional, structural and biological underpinnings of fatigue in MS and to assess the relative contribution of each factor. A cross-sectional study was conducted with 41 patients with relapsing–remitting multiple sclerosis and 21 healthy controls (female 14) (HC). MS patients were recruited by including only those with an Expanded Disability Status Scale score &lt; 4, and were categorized as fatigued (MS-F: 19, Female 13, FSS ≥ 4) or non-fatigued (MS-NF: 22, Female 11, FSS &lt; 4). Over five phases, participants underwent Transcranial Magnetic Stimulation, resting-state Electroencephalography, structural and functional Magnetic Resonance, clinical assessments, and blood tests for neurofilament light chain, serum glial fibrillary acidic protein and cytokine levels. Data were analysed using both non-parametric and parametric tests, based on the data distribution. Finally, a decision-tree model was applied to predict patient group assignment. Neurophysiologically, the two patient groups differed in several domains. Those with fatigue had increased θ-band EEG power in frontocentral regions with eyes open. Transcranial Magnetic Stimulation findings indicated significantly lower intracortical facilitation in the MS-F group. Neuroimaging revealed stronger functional connectivity between nodes of the Default Mode Network, between the left temporal node and the right prefrontal node, in the MS-F group. Furthermore, fractional anisotropy via Diffusion Tensor Imaging showed reduced white matter integrity in the corticospinal tracts and corpus callosum in these patients. No significant differences were observed in lesion load, brain volumes, clinical/psychological measures, or blood sample findings linked with neurodegeneration or inflammation; the only psychological variable that differed between the two groups was the depression scale score, with MS-F patients reporting higher scores than MS-NF patients. The decision tree analysis identified both ICF and significantly lower fractional anisotropy values as the most accurate predictors of fatigue, with a classification accuracy of 84.2%. Results highlight the importance of a multidisciplinary approach in defining central fatigue in multiple sclerosis, which would emerge through subtle, subclinical, regional abnormalities of myelin integrity and clearly manifest neurophysiological evidence of impaired glutamatergic activity in motor areas. They also suggest possible biomarkers for the diagnosis of fatigue, possibly useful for eventual targeting novel neuromodulatory treatments.
Linking movement-related beta oscillations to cortical excitability, structural damage, and fatigue in multiple sclerosis Elisa Tatti, Alberto Benelli, Alessandra Cinti, Rosa Cortese, Anna Serbina, Anna J Kulapurathazhe, Sophia Saed, Ludovico Luchetti, Javier Cudeiro, Jian Zhang, Anna de Mauro, Francesco Neri, Maria Laura Stromillo, Tommaso Lisini Baldi, Nicole d'Aurizio, Marco Battaglini, Domenico Plantone, Delia Righi, Elisa Massucco, Alessandro Giannotta, Francesco Lomi, Adriano Scoccia, Giuseppe Lai, Monica Ulivelli, Maria Felice Ghilardi, Nicola De Stefano, Simone Rossi Brain Communications, 2026 Fatigue is one of the most disabling symptoms of multiple sclerosis (MS), yet its neurobiology remains unclear, and there are no objective biomarkers. Previous studies using electroencephalography alone have revealed altered movement-related beta Event-Related Desynchronization (ERD) and Synchronization (ERS) dynamics in fatigued patients, but without providing mechanistic insight. In this cross-sectional study, we combined electroencephalography with transcranial magnetic stimulation, structural magnetic resonance imaging with diffusion tensor imaging (DTI), and clinical measures to probe the mechanistic basis of movement-related beta modulation depth (ERS-ERD) and its link with fatigue. Based on the Fatigue Severity Scale score (FSS), we enrolled 41 relapsing-remitting MS patients, 19 with clinically significant fatigue, 22 without (aged 25–55 years, 25 females), alongside 18 age- and sex-matched healthy volunteers. Participants underwent neuropsychological assessment, blood sampling for inflammatory and neurodegeneration-related biomarkers, structural magnetic resonance imaging with DTI to assess grey and white matter integrity, transcranial magnetic stimulation to quantify cortical excitatory and inhibitory balance, and continuous electroencephalography during 300 cued pinch movements to characterize movement-related beta dynamics. Compared with non-fatigued patients and healthy volunteers, fatigued patients exhibited reduced beta peak ERD to ERS modulation (P &lt; 0.001), especially in frontal regions. The modulation depth correlated with fatigue severity (ρ = −0.54, P = 0.0006), intracortical facilitation (ρ = 0.49, P = 0.0009), and caudate nucleus volume (ρ = 0.35, P = 0.010). A nested elastic-net logistic regression integrating demographic, clinical, structural, and functional markers showed robust held-out performance (mean Receiver Operating Characteristic-Area Under the Curve = 0.92, Precision Recall-Area Under the Curve = 0.83, accuracy = 0.89, Brier score = 0.10). Variables with the strongest protective association with fatigue were higher intracortical facilitation, better mental health, larger caudate volume, greater beta modulation over the frontal regions, and higher corticospinal tract and superior longitudinal fasciculus integrity. These findings support frontal beta modulation as a mechanistically grounded, non-invasive biomarker of central fatigue in multiple sclerosis and highlight its potential utility for clinical diagnosis and targeted therapeutic intervention.
Functional connectivity changes are associated with disability progression in multiple sclerosis: a longitudinal fMRI study Claudia Piervincenzi, Abhineet Ojha, Silvia Tommasin, Federica Satriano, Nikolaos Petsas, Antonio Gallo, Alessandro d’Ambrosio, Nicola De Stefano, Rosa Cortese, Paola Valsasina, Nicolò Tedone, Carlo Pozzilli, Maria A. Rocca, Massimo Filippi, Patrizia Pantano, , Costanza Giannì, Elena Barbuti, Loredana Storelli, Stefania Sala, Elisabetta Pagani, Paolo Preziosa, Alvino Bisecco, Riccardo Borgo, Valentina Rippa, Fabrizio Esposito, Maria Laura Stromillo, Riccardo Tappa Brocci, Viola Baione Journal of Neurology, 2025 Background Resting-state functional connectivity (FC) alterations in people with multiple sclerosis (PwMS) have been hypothesized to reflect either adaptive or maladaptive plasticity. Investigating FC longitudinal evolution and its relationship with disability progression can help clarify this issue. This study examined 5-year FC changes in pwMS and their clinical relevance. Methods From the Italian Neuroimaging Network Initiative database, we included 156 pwMS with two clinical visits and 3T-MRI scans acquired on the same scanner 4–6 years apart. Clinical/neuropsychological visits included the Expanded Disability Status Scale (EDSS), Nine-Hole Peg Test (9HPT), Timed 25-Foot Walk Test (T25FWT), Paced Auditory Serial Addition Test (PASAT3), and Symbol Digit Modalities Test (SDMT). One hundred fifty-six age- and sex-matched healthy subjects (HS) with baseline MRI and the same tests were also included. Based on the EDSS, pwMS were divided into three groups: low disability (0–1.5; N = 78), mild disability (2–3.5; N = 50), and high disability (≥ 4; N = 28). Resting-state networks (RSNs) were identified using independent component analysis. Baseline and longitudinal FC changes were correlated with baseline and follow-up clinical/neuropsychological measures. Results At baseline, the low-disability group showed significantly higher FC in all RSNs (FDR-corrected p < 0.05) compared to HS, which correlated with better baseline scores (SDMT, T25FWT) and less worsening at follow-up (PASAT3, 9HPT). The mild- and high-disability groups exhibited mixed FC abnormalities, with both higher and lower FC than HS in several RSNs. In the mild-disability group, higher FC was associated with worse baseline scores (SDMT, T25FWT) and greater clinical worsening (PASAT3, 9HPT, T25FWT). In the high-disability group, higher sensorimotor baseline FC correlated only with worse baseline 9HPT. Longitudinally, all RSNs showed FC increase in the low-disability group, but a FC decrease in the other groups. FC increases in the low-disability group generally correlated with better clinical outcome (T25FWT), while FC decreases in the mild-disability group correlated with clinical worsening (9HPT, T25FWT). Conclusions FC increases appear to reflect compensatory mechanisms in low-disability pwMS, while in more disabled patients, FC alterations likely represent maladaptive responses. These findings support resting-state FC as a biomarker for monitoring disease progression and treatment response in MS.
Clinically Relevant Patterns of Co-Fluctuating Structure and Function in Multiple Sclerosis Jian Zhang, Marco Battaglini, Rosa Cortese, Maria Laura Stromillo, Marzia Mortilla, Ludovico Luchetti, Giordano Gentile, Emilio Portaccio, Maria Pia Amato, Menno M. Schoonheim, Nicola De Stefano European Journal of Neurology, 2025 Background While structural and functional connectivity changes in multiple sclerosis (MS) are well documented, their complex interplay remains poorly understood. This study identifies co‐fluctuating patterns of structural and functional changes in MS using an MRI‐based multimodal fusion approach and assesses the added value to clinical outcomes. Methods Linked independent component analysis (ICA) was applied to spatial maps of white matter (WM) lesions, fractional anisotropy (FA), gray matter (GM) volume, and functional network connectivity to detect regions with differential co‐fluctuations. Graph theory (GT) was then used to reveal clusters of interconnected brain regions. Linear mixed‐effect models targeted regions with significantly different co‐fluctuating patterns between MS and HC. Multivariate stepwise regressions analyzed the associations between co‐fluctuating patterns and disability and cognitive dysfunction. Results The study included 147 patients with MS and 57 HC. Significant co‐fluctuating patterns of decreased FA, increased lesion probability in the thalamic radiation and corpus callosum, GM atrophy in sensorimotor and thalamic areas, and enhanced functional connectivity in the temporal parietal network distinguished MS from HC ( p < 0.001). GT revealed eight brain sub‐networks of spatially connected clusters. Regional‐ and modality‐specific loadings and GT changes explained physical (adjusted R 2 = 0.51, p < 0.001) and cognitive (adjusted R 2 = 0.44, p < 0.001) disability better than traditional MRI measures (adjusted R 2 = 0.12–0.33, p < 0.001). Conclusions Our multimodal MRI approach revealed co‐fluctuating regional patterns of lesions, structural disconnection, and functional hyperconnectivity in MS, offering a more comprehensive explanation of clinical outcomes than traditional MRI metrics.
Comparative Analysis of SiMoA and Ella Immunoassay Platforms for Measuring Serum Neurofilament Light Chain Levels in ATTRv With Polyneuropathy and Presymptomatic Carriers Guido Primiano, Marco Luigetti, Delia Righi, Angela Romano, Luca Leonardi, Valeria Guglielmino, Francesca Forcina, Marco Ceccanti, Maurizio Inghilleri, Fiore Manganelli, Stefano Tozza, Maria Ausilia Sciarrone, Francesca Vitali, Andrea Sabino, Carlo Manco, Angela Stufano, Maria Laura Stromillo, Nicola De Stefano, Paolo Calabresi, Domenico Plantone European Journal of Neurology, 2025 BackgroundNeurofilament light chains (NfL) represent reliable serum biomarkers of neuroaxonal injury. Due to their low serum levels, precise detection methods are critical. This study aimed to scrutinize the comparability of two techniques: Single Molecule Array (SiMoA) and Ella automated immunoassay, analyzing serum NfL levels in ATTRv presymptomatic subjects and polyneuropathy patients.MethodsBlood samples were processed and analyzed using commercial Ella and SiMoA kits. Statistical analysis included the Wilcoxon signed‐rank test, Spearman correlation, Bland–Altman, and Passing‐Bablok regression. ANCOVA models were used to compare NfL levels between cohorts.ResultsThe study measured serum NfL levels in 55 symptomatic and 55 presymptomatic ATTRv subjects. Median NfL concentrations were significantly higher with Ella (median 27.5 pg/mL) than SiMoA (median 15.9 pg/mL). Both methods showed a strong positive correlation (r = 0.8, p < 0.001), but Ella overestimated NfL by 42%. Bland–Altman analysis revealed a mean bias of 15.4 pg/mL, with limits of agreement between −41.1 and 72.0 pg/mL. The slope of the Passing–Bablok regression line was 0.58, and the intercept was 3.48 pg/mL, suggesting that the Ella platform tends to overestimate NfL concentrations compared to the SiMoA platform, especially at higher concentrations. Both methods effectively distinguished presymptomatic from symptomatic patients (p < 0.001 for both).ConclusionsOur findings underscore that both platforms are effective in measuring serum NfL, with Ella consistently overestimating, especially at higher concentrations. The difference between the two platforms must be taken into account when deeming the concentrations as pathological or normal, as well as when conducting longitudinal studies.
Elevated serum concentrations of GFAP in hereditary transthyretin amyloidosis since pre-symptomatic stages Domenico Plantone, Marco Luigetti, Carlo Manco, Angela Romano, Luca Leonardi, Valeria Guglielmino, Francesca Forcina, Marco Ceccanti, Maurizio Inghilleri, Fiore Manganelli, Stefano Tozza, Maria Ausilia Sciarrone, Francesca Vitali, Andrea Sabino, Delia Righi, Angela Stufano, Maria Laura Stromillo, Nicola De Stefano, Paolo Calabresi, Guido Primiano Journal of Neurology, 2025 Background Hereditary transthyretin amyloidosis (ATTRv) is a rare disorder caused by pathogenic TTR gene variants. Glial fibrillary acidic protein (GFAP) and neurofilament light chain (NfL) are potential biomarkers for astrocyte activation and neuroaxonal damage, respectively. This study investigates serum GFAP (sGFAP) and NfL (sNfL) levels in ATTRv patients, pre-symptomatic subjects, and healthy controls (HCs) to evaluate their utility as biomarkers of disease progression and CNS involvement. Methods Our multicenter cross-sectional study included 111 ATTRv patients (56 symptomatic, 55 pre-symptomatic subjects) and 183 HCs. Serum levels of sGFAP and sNfL were measured using ultrasensitive immunoassays. The statistical comparisons were performed using ANCOVA models (age and sex adjusted), with correlations examined between serum biomarkers and disease severity (Neuropathy Impairment Score, NIS). Results sGFAP levels were elevated in symptomatic (median: 238.35 pg/ml) and pre-symptomatic subjects (median: 105.50 pg/ml) vs. HCs (median: 75.5 pg/ml, p < 0.001). sNfL was elevated only in symptomatic patients (median: 43.68 pg/ml) compared to pre-symptomatic subjects (median: 9.36 pg/ml) and HCs (median: 7.54 pg/ml, p < 0.001). Both biomarkers correlated significantly with NIS, reflecting disease severity. Female HCs had higher sGFAP levels than males (median 88.6 pg/ml vs. 59.8 pg/ml; p 0.011). Conclusion sGFAP and sNfL mark distinct ATTRv stages, with sGFAP indicating early preclinical changes and sNfL correlating with neurological progression. Sex differences in sGFAP levels among HCs suggest that sex should be considered as a covariate in biomarker analyses.
Maternal and fetal outcomes in an Italian multicentric cohort of women with multiple sclerosis exposed to dimethyl fumarate during pregnancy Doriana Landi, Silvia Bartolomeo, Francesca Bovis, Maria Pia Amato, Simona Bonavita, Giovanna Borriello, Maria Buccafusca, Sebastiano Bucello, Paola Cavalla, Maria Cellerino, Diego Centonze, Eleonora Cocco, Antonella Conte, Antonio Cortese, Emanuele D’Amico, Massimiliano Di Filippo, Renato Docimo, Roberta Fantozzi, Elisabetta Ferraro, Massimo Filippi, Matteo Foschi, Antonio Gallo, Franco Granella, Antonio Ianniello, Roberta Lanzillo, Lorena Lorefice, Matteo Lucchini, Giacomo Lus, Giorgia Mataluni, Massimiliano Mirabella, Lucia Moiola, Francesca Napoli, Carolina Gabri Nicoletti, Francesco Patti, Paolo Ragonese, Sabrina Realmuto, Giuseppe Schirò, Elisabetta Signoriello, Leonardo Sinisi, Maria Laura Stromillo, Valentina Tomassini, Domizia Vecchio, Maria Pia Sormani, Girolama Alessandra Marfia Multiple Sclerosis Journal, 2024 Background: Evidence on the impact of dimethyl fumarate (DMF) during pregnancy in women with multiple sclerosis (MS) is limited. Objectives: To investigate disease activity and pregnancy outcomes in a retrospective cohort of women exposed to DMF in early pregnancy. Methods: Women discontinuing DMF after pregnancy confirmation were identified from 29 Italian MS Centers. Disease activity 12 months before conception, during pregnancy, and 12 months postpartum were recorded, exploring reactivation predictors. Pregnancy and fetal outcomes were assessed. Results: The study analyzed 137 pregnancies (12 pregnancy losses, 125 live births) from 137 women (mean age 32.9 ± 4.7 years), discontinuing DMF within a median (interquartile range (IQR)) interval of 4.9 (3.7–5.7) weeks from conception. In live birth pregnancies, annualized relapse rate (ARR) significantly decreased during pregnancy (ARR = 0.07, 95% confidence interval (CI): 0.03–0.14, p = 0.021) compared to pre-conception (ARR = 0.21 (95% CI: 0.14–0.30)) and increased postpartum ((ARR = 0.22 (95% CI: 0.15–0.32), p = 0.006). Median time to first relapse (TTFR) was 3.16 (IQR: 1:87–5.42) months. Higher pre-conception relapse number (hazard ratio (HR) = 2.33, 95% CI: 1.08–5.02) and Expanded Disability Status Scale (EDSS; HR = 1.81, 95% CI: 1.17-2.74) were associated with shorter TTFR, while treatment resumption with longer TTFR (HR = 0.29, 95% CI: 0.11–0.74). Fetal outcomes were unaffected by DMF exposure. Conclusion: DMF discontinuation does not increase relapse risk during pregnancy. Early therapy restart prevents postpartum relapses. Early DMF exposure shows no adverse fetal outcomes.
Regional hippocampal atrophy reflects memory impairment in patients with early relapsing remitting multiple sclerosis Rosa Cortese, Marco Battaglini, Maria Laura Stromillo, Ludovico Luchetti, Matteo Leoncini, Giordano Gentile, Daniele Gasparini, Domenico Plantone, Manuela Altieri, Alessandro D’Ambrosio, Antonio Gallo, Costanza Giannì, Claudia Piervincenzi, Patrizia Pantano, Elisabetta Pagani, Paola Valsasina, Paolo Preziosa, Nicolo’ Tedone, Maria Assunta Rocca, Massimo Filippi, Nicola De Stefano, , Alvino Bisecco, Fabrizio Esposito, Alessandro De Rosa, Serena Ruggieri, Silvia Tommasin, Nikolaos Petsas, Loredana Storelli, Stefania Sala Journal of Neurology, 2024
ChatGPT vs. neurologists: a cross-sectional study investigating preference, satisfaction ratings and perceived empathy in responses among people living with multiple sclerosis Elisabetta Maida, Marcello Moccia, Raffaele Palladino, Giovanna Borriello, Giuseppina Affinito, Marinella Clerico, Anna Maria Repice, Alessia Di Sapio, Rosa Iodice, Antonio Luca Spiezia, Maddalena Sparaco, Giuseppina Miele, Floriana Bile, Cristiano Scandurra, Diana Ferraro, Maria Laura Stromillo, Renato Docimo, Antonio De Martino, Luca Mancinelli, Gianmarco Abbadessa, Krzysztof Smolik, Lorenzo Lorusso, Maurizio Leone, Elisa Leveraro, Francesca Lauro, Francesca Trojsi, Lidia Mislin Streito, Francesca Gabriele, Fabiana Marinelli, Antonio Ianniello, Federica De Santis, Matteo Foschi, Nicola De Stefano, Vincenzo Brescia Morra, Alvino Bisecco, Giancarlo Coghe, Eleonora Cocco, Michele Romoli, Francesco Corea, Letizia Leocani, Jessica Frau, Simona Sacco, Matilde Inglese, Antonio Carotenuto, Roberta Lanzillo, Alessandro Padovani, Maria Triassi, Simona Bonavita, Luigi Lavorgna, and Journal of Neurology, 2024
Time is myelin: early cortical myelin repair prevents atrophy and clinical progression in multiple sclerosis Andrea Lazzarotto, Mariem Hamzaoui, Matteo Tonietto, Anne-Laure Dubessy, Michael Khalil, Lukas Pirpamer, Stefan Ropele, Christian Enzinger, Marco Battaglini, Maria Laura Stromillo, Nicola De Stefano, Massimo Filippi, Maria Assunta Rocca, Paolo Gallo, Claudio Gasperini, Bruno Stankoff, Benedetta Bodini, , F Barkhof, N de Stefano, J Sastre-Garriga, O Ciccarelli, C Enzinger, M Filippi, Claudio Gasperini, L Kappos, J Palace, H Vrenken, À Rovira, M A Rocca, T Yousry Brain, 2024
Assessing treatment response to oral drugs for multiple sclerosis in real-world setting: A MAGNIMS Study Serena Ruggieri, Luca Prosperini, Sarmad Al-Araji, Pietro Osvaldo Annovazzi, Alvino Bisecco, Olga Ciccarelli, Nicola De Stefano, Massimo Filippi, Vinzenz Fleischer, Nikos Evangelou, Christian Enzinger, Antonio Gallo, Afagh Garjani, Sergiu Groppa, Shalom Haggiag, Michael Khalil, Matteo Lucchini, Massimiliano Mirabella, Xavier Montalban, Carlo Pozzilli, Paolo Preziosa, Jordi Río, Maria A Rocca, Alex Rovira, Maria L Stromillo, Mauro Zaffaroni, Carla Tortorella, Claudio Gasperini Journal of Neurology Neurosurgery and Psychiatry, 2023
Quality of care provided by Multiple Sclerosis Centers during Covid-19 pandemic: Results of an Italian multicenter patient-centered survey Manuela Altieri, Rocco Capuano, Alvino Bisecco, Alessandro d'Ambrosio, Mario Risi, Paola Cavalla, Marco Vercellino, Pietro Annovazzi, Mauro Zaffaroni, Nicola De Stefano, Maria Laura Stromillo, Emanuele D'Amico, Aurora Zanghì, Maria Chiara Buscarinu, Roberta Lanzillo, Giovanna De Luca, Massimiliano Calabrese, Lorena Lorefice, Massimiliano Di Filippo, Paola Valentino, Alberto Gajofatto, Girolama Alessandra Marfia, Aurora Fuiani, Viviana Nociti, Gioacchino Tedeschi, Antonio Gallo Multiple Sclerosis and Related Disorders, 2023
Antibody response elicited by the SARS-CoV-2 vaccine booster in patients with multiple sclerosis: Who gains from it? Irene Schiavetti, Matilde Inglese, Jessica Frau, Elisabetta Signoriello, Francesca Caleri, Maria Laura Stromillo, Maria Teresa Ferrò, Maria Teresa Rilla, Ilaria Gandoglia, Paola Gazzola, Giampaolo Brichetto, Livia Pasquali, Luigi Grimaldi, Monica Ulivelli, Fabiana Marinelli, Susanna Cordera, Marinella Clerico, Antonella Conte, Marco Salvetti, Mario Alberto Battaglia, Diego Franciotta, Antonio Uccelli, Maria Pia Sormani, and European Journal of Neurology, 2023
Multicenter data harmonization for regional brain atrophy and application in multiple sclerosis Elisabetta Pagani, Loredana Storelli, Patrizia Pantano, Nikolaos Petsas, Gioacchino Tedeschi, Antonio Gallo, Nicola De Stefano, Marco Battaglini, Maria A. Rocca, Massimo Filippi, , Paola Valsasina, Mauro Sibilia, Paolo Preziosa, Alvino Bisecco, Alessandro d’Ambrosio, Manuela Altieri, Rocco Capuano, Silvia Tommasin, Serena Ruggieri, Claudia Piervincenzi, Costanza Gianni, Maria Laura Stromillo, Rosa Cortese, Paola Zaratin Journal of Neurology, 2023
Signs and symptoms of COVID-19 in patients with multiple sclerosis Irene Schiavetti, Luca Carmisciano, Marta Ponzano, Cinzia Cordioli, Eleonora Cocco, Girolama Alessandra Marfia, Matilde Inglese, Massimo Filippi, Marta Radaelli, Roberto Bergamaschi, Paolo Immovilli, Marco Capobianco, Nicola De Rossi, Giampaolo Brichetto, Cinzia Scandellari, Paola Cavalla, Ilaria Pesci, Paolo Confalonieri, Paola Perini, Maria Trojano, Roberta Lanzillo, Gioacchino Tedeschi, Giancarlo Comi, Mario Alberto Battaglia, Francesco Patti, Marco Salvetti, Maria Pia Sormani, and European Journal of Neurology, 2022
Breakthrough SARS-CoV-2 infections in MS patients on disease-modifying therapies Irene Schiavetti, Cinzia Cordioli, Maria Laura Stromillo, Maria Teresa Ferrò, Alice Laroni, Eleonora Cocco, Gaia Cola, Livia Pasquali, Maria Teresa Rilla, Elisabetta Signoriello, Rosa Iodice, Alessia Di Sapio, Roberta Lanzillo, Francesca Caleri, Pietro Annovazzi, Antonella Conte, Giuseppe Liberatore, Francesca Ruscica, Renato Docimo, Simona Bonavita, Monica Ulivelli, Paola Cavalla, Francesco Patti, Diana Ferraro, Marinella Clerico, Paolo Immovilli, Massimiliano Di Filippo, Marco Salvetti, Maria Pia Sormani Multiple Sclerosis Journal, 2022
Breakthrough SARS-CoV-2 infections after COVID-19 mRNA vaccination in MS patients on disease modifying therapies during the Delta and the Omicron waves in Italy Maria Pia Sormani, Irene Schiavetti, Matilde Inglese, Luca Carmisciano, Alice Laroni, Caterina Lapucci, Valeria Visconti, Carlo Serrati, Ilaria Gandoglia, Tiziana Tassinari, Germana Perego, Giampaolo Brichetto, Paola Gazzola, Antonio Mannironi, Maria Laura Stromillo, Cinzia Cordioli, Doriana Landi, Marinella Clerico, Elisabetta Signoriello, Eleonora Cocco, Jessica Frau, Maria Teresa Ferrò, Alessia Di Sapio, Livia Pasquali, Monica Ulivelli, Fabiana Marinelli, Matteo Pizzorno, Graziella Callari, Rosa Iodice, Giuseppe Liberatore, Francesca Caleri, Anna Maria Repice, Susanna Cordera, Mario Alberto Battaglia, Marco Salvetti, Diego Franciotta, Antonio Uccelli, Alessandro Maglione, Alessia Di Sapio, Alessio Signori, Alice Laroni, Aniello Iovino, Anna Maria Repice, Antonio Mannironi, Antonio Uccelli, Carlo Serrati, Carolina Gabri Nicoletti, Caterina Lapucci, Chiara Rosa Mancinelli, Cinzia Cordioli, Daiana Bezzini, Daniele Carmagnini, Davide Brogi, Diego Franciotta, Doriana Landi, Eduardo Nobile Orazio, Eleonora Cocco, Elisabetta Signoriello, Enri Nako, Ester Assandrir, Fabiana Marinelli, Federica Baldi, Filippo Ansaldi, Francesca Bovis, Francesca Caleri, Gabriele Siciliano, Gaia Cola, Germana Perego, Giacomo Lus, Giampaolo Brichetto, Giancarlo Icardi, Gianmarco Bellucci, Giorgio Da Rin, Girolama Alessandra Marfia, Giulia Vazzoler, Giuseppe Liberatore, Giuseppe Trivelli, Graziella Callari, Ilaria Gandoglia, Ilaria Maietta, Irene Schiavetti, Jessica Frau, Laura Sticchi, Livia Pasquali, Lorena Lorefice, Luca Carmisciano, Lucia Ruggiero, Marcello Manzino, Marco Salvetti, Margherita Monti Bragadin, Maria Chiara Buscarinu, Maria Gagliardi, Maria Laura Stromillo, Maria Pia Sormani, Maria Teresa Ferrò, Maria Teresa Rilla, Marinella Clerico, Mario Alberto Battaglia, Marta Ponzano, Marzia Fronza, Massimo Del Sette, Matilde Inglese, Matteo Scialabba, Michele Bedognetti, Monica Ulivelli, Nicola De Rossi, Nicola De Stefano, Paola Gazzola, Rachele Bigi, Raffaele Dubbioso, Roberta Reniè, Rosa Iodice, Sabrina Fabbri, Sarah Rasia, Simona Rolla, Stefan Platzgummer, Susanna Cordera, Tiziana Tassinari, Valentina Carlini Ebiomedicine, 2022
SARS-CoV-2 serology after COVID-19 in multiple sclerosis: An international cohort study Maria Pia Sormani, Irene Schiavetti, Doriana Landi, Luca Carmisciano, Nicola De Rossi, Cinzia Cordioli, Lucia Moiola, Marta Radaelli, Paolo Immovilli, Marco Capobianco, Vincenzo Brescia Morra, Maria Trojano, Gioacchino Tedeschi, Giancarlo Comi, Mario Alberto Battaglia, Francesco Patti, Yara Dadalti Fragoso, Sedat Sen, Aksel Siva, Roberto Furlan, Marco Salvetti, Gianmarco Abbadessa, Umberto Aguglia, Lia Allegorico, Rossi Beatrice Maria Allegri, Maria Pia Amato, Pietro Annovazzi, Carlo Antozzi, Lucia Appendino, Sebastiano Arena, Viola Baione, Roberto Balgera, Valeria Barcella, Damiano Baroncini, Caterina Barrilà, Mario A. Battaglia, Alessandra Bellacosa, Gianmarco Bellucci, Roberto Bergamaschi, Valeria Bergamaschi, Daiana Bezzini, Beatrice Biolzi, Alvino Bisecco, Simona Bonavita, Giovanna Borriello, Chiara Bosa, Antonio Bosco, Francesca Bovis, Marco Bozzali, Laura Brambilla, Morra Vincenzo Brescia, Giampaolo Brichetto, Maria Buccafusca, Elisabetta Bucciantini, Sebastiano Bucello, Maria Chiara Buscarinu, Maria Paola Cabboi, Massimiliano Calabrese, Francesca Calabria, Francesca Caleri, Federico Camilli, Luisa Maria Caniatti, Roberto Cantello, Marco Capobianco, Ruggero Capra, Rocco Capuano, Luca Carmisciano, Patrizia Carta, Paola Cavalla, Maria Grazia Celani, Maria Cellerino, Raffaella Cerqua, Clara Chisari, Raffaella Clerici, Marinella Clerico, Eleonora Cocco, Gaia Cola, Giancarlo Comi, Paolo Confalonieri, Antonella Conte, Marta Zaffira Conti, Christian Cordano, Susanna Cordera, Cinzia Cordioli, Francesco Corea, Claudio Correale, Salvatore Cottone, Francesco Crescenzo, Erica Curti, Alessandro d’Ambrosio, Emanuele D’Amico, Maura Chiara Danni, Alessia d’Arma, Vincenzo Dattola, Stefano de Biase, Giovanna De Luca, Stefania Federica De Mercanti, Paolo De Mitri, Nicola De Rossi, Nicola De Stefano, Marco Della Cava, Mario di Napoli, Alessia Di Sapio, Renato Docimo, Anna Dutto, Luana Evangelista, Salvatore Fanara, Diana Ferraro, Maria Teresa Ferrò, Massimo Filippi, Cristina Fioretti, Mario Fratta, Jessica Frau, Marzia Fronza, Roberto Furlan, Alberto Gajofatto, Antonio Gallo, Paolo Gallo, Claudio Gasperini, Anna Ghazaryan, Bruno Giometto, Francesca Gobbin, Flora Govone, Franco Granella, Erica Grange, Maria Grazia Grasso, Angelica Guareschi, Clara Guaschino, Simone Guerrieri, Donata Guidetti, Pietro Iaffaldano, Antonio Ianniello, Luigi Iasevoli, Paolo Immovilli, Daniele Imperiale, Maria Teresa Infante, Matilde Inglese, Rosa Iodice, Aniello Iovino, Giovanna Konrad, Doriana Landi, Roberta Lanzillo, Caterina Lapucci, Luigi Lavorgna, Rita L’Episcopo Maria, Serena Leva, Giuseppe Liberatore, Marianna Lo Re, Marco Longoni, Leonardo Lopiano, Lorena Lorefice, Matteo Lucchini, Giacomo Lus, Davide Maimone, Maria Malentacchi, Giulia Mallucci, Simona Malucchi, Chiara Rosa Mancinelli, Luca Mancinelli, Paolo Manganotti, Teresa Giorgia Maniscalco, Vittorio Mantero, Sabrina Marangoni, Damiano Marastoni, Alessandra Girolama Marfia, Fabiana Marinelli, Alessandro Marti, Filippo Martinelli Boneschi, Federco Masserano Zoli, Francesca Matta, Laura Mendozzi, Giuseppe Meucci, Silvia Miante, Giuseppina Miele, Eva Milano, Massimiliano Mirabella, Rosanna Missione, Marcello Moccia, Lucia Moiola, Sara Montepietra, Margherita Monti Bragadin, Federico Montini, Roberta Motta, Raffaele Nardone, Carolina Gabri Nicoletti, Eduardo Nobile-Orazio, Agostino Nozzolillo, Marco Onofrj, Riccardo Orlandi, Anna Palmieri, Damiano Paolicelli, Livia Pasquali, Luisa Pastò, Francesco Patti, Elisabetta Pedrazzoli, Paola Perini, Ilaria Pesci, Maria Petracca, Alfredo Petrone, Carlo Piantadosi, Anna M. Pietroboni, Federica Pinardi, Marta Ponzano, Emilio Portaccio, Mattia Pozzato, Carlo Pozzilli, Luca Prosperini, Alessandra Protti, Marta Radaelli, Paolo Ragonese, Sarah Rasia, Sabrina Realmuto, Anna Repice, Eleonora Rigoni, Maria Teresa Rilla, Francesca Rinaldi, Calogero Marcello Romano, Marco Ronzoni, Marco Rovaris, Francesca Ruscica, Loredana Sabattini, Giuseppe Salemi, Marco Salvetti, Lorenzo Saraceno, Alessia Sartori, Arianna Sartori, Elvira Sbragia, Cinzia Scandellari, Ilaria Scarano Giuditta, Valentina Scarano, Irene Schiavetti, Valentina Schillaci, Maria Sessa, Caterina Sgarito, Grazia Sibilia, Gabriele Siciliano, Alessio Signori, Elisabetta Signoriello, Leonardo Sinisi, Francesca Sireci, Patrizia Sola, Claudio Solaro, Maria Pia Sormani, Stefano Sotgiu, Maddalena Sparaco, Maria Laura Stromillo, Silvia Strumia, Laura Emanuela Susani, Giulietta Tabiadon, Francesco Teatini, Gioacchino Tedeschi, Valentina Tomassini, Simone Tonietti, Clerici Valentina Torri, Carla Tortorella, Simona Toscano, Rocco Totaro, Maria Trojano, Maria Trotta, Gabriella Turano, Monica Ulivelli, Manzo Valentino, Giovanna Vaula, Domizia Vecchio, Marco Vercellino, Elena Pinuccia Verrengia, Marika Vianello, Eleonora Virgilio, Francesca Vitetta, Stefano Vollaro, Mauro Zaffaroni, Mauro Zampolini, Ignazio Roberto Zarbo, Antonio Zito, Luigi Zuliani Multiple Sclerosis Journal, 2022
Effect of BDNF Val66Met polymorphism on hippocampal subfields in multiple sclerosis patients Ermelinda De Meo, Emilio Portaccio, Elio Prestipino, Benedetta Nacmias, Silvia Bagnoli, Lorenzo Razzolini, Luisa Pastò, Claudia Niccolai, Benedetta Goretti, Angelo Bellinvia, Mattia Fonderico, Antonio Giorgio, Maria Laura Stromillo, Massimo Filippi, Sandro Sorbi, Nicola De Stefano, Maria Pia Amato Molecular Psychiatry, 2022
Effect of SARS-CoV-2 mRNA vaccination in MS patients treated with disease modifying therapies Maria Pia Sormani, Matilde Inglese, Irene Schiavetti, Luca Carmisciano, Alice Laroni, Caterina Lapucci, Giorgio Da Rin, Carlo Serrati, Ilaria Gandoglia, Tiziana Tassinari, Germana Perego, Giampaolo Brichetto, Paola Gazzola, Antonio Mannironi, Maria Laura Stromillo, Cinzia Cordioli, Doriana Landi, Marinella Clerico, Elisabetta Signoriello, Jessica Frau, Maria Teresa Ferrò, Alessia Di Sapio, Livia Pasquali, Monica Ulivelli, Fabiana Marinelli, Graziella Callari, Rosa Iodice, Giuseppe Liberatore, Francesca Caleri, Anna Maria Repice, Susanna Cordera, Mario Alberto Battaglia, Marco Salvetti, Diego Franciotta, Antonio Uccelli, Alessandro Maglione, Alessia Di Sapio, Alessio Signori, Alice Laroni, Aniello Iovino, Anna Maria Repice, Antonio Mannironi, Antonio Uccelli, Carlo Serrati, Carolina Gabri Nicoletti, Caterina Lapucci, Chiara Rosa Mancinelli, Cinzia Cordioli, Daiana Bezzini, Daniele Carmagnini, Davide Brogi, Diego Franciotta, Doriana Landi, Eduardo Nobile Orazio, Eleonora Cocco, Elisabetta Signoriello, Enri Nako, Ester Assandri, Fabiana Marinelli, Federica Baldi, Filippo Ansaldi, Francesca Bovis, Francesca Caleri, Gabriele Siciliano, Gaia Cola, Germana Perego, Giacomo Lus, Giampaolo Brichetto, Giancarlo Icardi, gianmarco bellucci, Giorgio Da Rin, Girolama Alessandra Marfia, Giulia Vazzoler, Giuseppe Liberatore, Giuseppe Trivelli, Graziella Callari, Ilaria Gandoglia, Ilaria Maietta, Irene Schiavetti, Jessica Frau, Laura Sticchi, Livia Pasquali, Lorena Lorefice, Luca Carmisciano, Lucia Ruggiero, Marcello Manzino, Marco Salvetti, Margherita Monti Bragadin, Maria Chiara Buscarinu, Maria Gagliardi, Maria Laura Stromillo, Maria Pia Sormani, Maria Teresa Ferrò, Maria Teresa Rilla, Marinella Clerico, Mario Alberto Battaglia, Marta Ponzano, Marzia Fronza, Massimo Del Sette, Matilde Inglese, Matteo Scialabba, Michele Bedognetti, Monica Ulivelli, Nicola De Rossi, Nicola De Stefano, Paola Gazzola, Rachele Bigi, Raffaele Dubbioso, Roberta Reniè, Rosa Iodice, Sabrina Fabbri, Sarah Rasia, Simona Rolla, Stefan Platzgummer, Susanna Cordera, Tiziana Tassinari, Valentina Carlini Ebiomedicine, 2021
Disease-Modifying Therapies and Coronavirus Disease 2019 Severity in Multiple Sclerosis Maria P. Sormani, Nicola De Rossi, Irene Schiavetti, Luca Carmisciano, Cinzia Cordioli, Lucia Moiola, Marta Radaelli, Paolo Immovilli, Marco Capobianco, Maria Trojano, Paola Zaratin, Gioacchino Tedeschi, Giancarlo Comi, Mario A. Battaglia, Francesco Patti, Marco Salvetti, and Annals of Neurology, 2021
Telemedicine for management of patients with amyotrophic lateral sclerosis through COVID-19 tail Alessandro Bombaci, Gianmarco Abbadessa, Francesca Trojsi, Letizia Leocani, Simona Bonavita, Luigi Lavorgna, , Gioacchino Tedeschi, Giovanni Mancardi, Alessandro Padovani, Marinella Clerico, Francesco Brigo, Roberta Lanzillo, Antonio Russo, Bruno Giometto, Giulia Straccia, Rosa Iodice, Sebastiano Bucello, Pietro Annovazzi, Marcello Moccia, Luca Prosperini, Maria Laura Stromillo, Anna Maria Repice, Giuseppina Miele, Alberto Lerario, Antonio De Martino, Francesco Iodice, Francesco Di Lorenzo, Luca Cuffaro, Michele Romoli, Marcello Silvestro, Carlo Alberto Artusi Neurological Sciences, 2021
Cladribine vs other drugs in MS: Merging randomized trial with real-life data Alessio Signori, Francesco Saccà, Roberta Lanzillo, Giorgia Teresa Maniscalco, Elisabetta Signoriello, Anna Maria Repice, Pietro Annovazzi, Damiano Baroncini, Marinella Clerico, Eleonora Binello, Raffaella Cerqua, Giorgia Mataluni, Paola Perini, Simona Bonavita, Luigi Lavorgna, Ignazio Roberto Zarbo, Alice Laroni, Lorena Pareja-Gutierrez, Sara La Gioia, Barbara Frigeni, Valeria Barcella, Jessica Frau, Eleonora Cocco, Giuseppe Fenu, Valentina Torri Clerici, Arianna Sartori, Sarah Rasia, Cinzia Cordioli, Maria Laura Stromillo, Alessia Di Sapio, Simona Pontecorvo, Roberta Grasso, Stefania Barone, Caterina Barrilà, Cinzia Valeria Russo, Sabrina Esposito, Domenico Ippolito, Doriana Landi, Andrea Visconti, Maria Pia Sormani Neurology R Neuroimmunology Neuroinflammation, 2020
First therapy choice in newly diagnosed Multiple Sclerosis patients: A multicenter Italian study Giorgia T. Maniscalco, Francesco Saccà, Roberta Lanzillo, Pietro Annovazzi, Damiano Baroncini, Eleonora Binello, Annamaria Repice, Paola Perini, Marinella Clerico, Giorgia Mataluni, Simona Bonavita, Sara La Gioia, Lorena Pareja Gutierrez, Alice Laroni, Jessica Frau, Eleonora Cocco, Valentina Torri Clerici, Ignazio Roberto Zarbo, Arianna Sartori, Elisabetta Signoriello, Sarah Rasia, Cinzia Cordioli, Maria Laura Stromillo, Raffaella Cerqua, Simona Pontecorvo, Alessia Di Sapio, Roberta Grasso, Stefania Barone, Luigi Lavorgna, Caterina Barrilà, Doriana Landi, Cinzia Valeria Russo, Barbara Frigeni, Domenico Ippolito, Gabriella Turano, Luca Carmisciano, Maria Pia Sormani, Alessio Signori Multiple Sclerosis and Related Disorders, 2020
The Use of Social Media and Digital Devices Among Italian Neurologists Luigi Lavorgna, Francesco Brigo, Gianmarco Abbadessa, Sebastiano Bucello, Marinella Clerico, Eleonora Cocco, Rosa Iodice, Roberta Lanzillo, Letizia Leocani, Alberto Lerario, Marcello Moccia, Alessandro Padovani, Luca Prosperini, Anna Repice, Maria Stromillo, Francesca Trojsi, Gianluigi Mancardi, Gioacchino Tedeschi, Simona Bonavita Frontiers in Neurology, 2020
Reduced dynamics of functional connectivity and cognitive impairment in multiple sclerosis Alessandro d’Ambrosio, Paola Valsasina, Antonio Gallo, Nicola De Stefano, Deborah Pareto, Frederik Barkhof, Olga Ciccarelli, Christian Enzinger, Gioacchino Tedeschi, M Laura Stromillo, Maria J Arévalo, Hanneke E Hulst, Nils Muhlert, Marisa Koini, Massimo Filippi, Maria A Rocca Multiple Sclerosis Journal, 2020
"Better explanations" in multiple sclerosis diagnostic workup: A 3-year longitudinal study Massimiliano Calabrese, Claudio Gasperini, Carla Tortorella, Gianmarco Schiavi, Giovanni Frisullo, Paolo Ragonese, Roberta Fantozzi, Luca Prosperini, Pietro Annovazzi, Cinzia Cordioli, Massimiliano Di Filippo, Diana Ferraro, Alberto Gajofatto, Simona Malucchi, Salvatore Lo Fermo, Giovanna De Luca, Maria L. Stromillo, Eleonora Cocco, Antonio Gallo, Damiano Paolicelli, Roberta Lanzillo, Valentina Tomassini, Ilaria Pesci, Maria E. Rodegher, Claudio Solaro, the RIREMS group (Rising Italian Researchers in Multiple Sclerosis) Neurology, 2019
Clinical activity after fingolimod cessation: disease reactivation or rebound? J. Frau, M. P. Sormani, A. Signori, S. Realmuto, D. Baroncini, P. Annovazzi, E. Signoriello, G. T. Maniscalco, S. La Gioia, C. Cordioli, B. Frigeni, S. Rasia, G. Fenu, R. Grasso, A. Sartori, R. Lanzillo, M. L. Stromillo, S. Rossi, B. Forci, E. Cocco, the i‐MuST study group European Journal of Neurology, 2018
Deep gray matter volume loss drives disability worsening in multiple sclerosis Arman Eshaghi, Ferran Prados, Wallace J. Brownlee, Daniel R. Altmann, Carmen Tur, M. Jorge Cardoso, Floriana De Angelis, Steven H. van de Pavert, Niamh Cawley, Nicola De Stefano, M. Laura Stromillo, Marco Battaglini, Serena Ruggieri, Claudio Gasperini, Massimo Filippi, Maria A. Rocca, Alex Rovira, Jaume Sastre‐Garriga, Hugo Vrenken, Cyra E. Leurs, Joep Killestein, Lukas Pirpamer, Christian Enzinger, Sebastien Ourselin, Claudia A.M. Gandini Wheeler‐Kingshott, Declan Chard, Alan J. Thompson, Daniel C. Alexander, Frederik Barkhof, Olga Ciccarelli, on behalf of the MAGNIMS study group Annals of Neurology, 2018
Assessing response to interferon-β in a multicenter dataset of patients with MS Maria Pia Sormani, Claudio Gasperini, Marzia Romeo, Jordi Rio, Massimiliano Calabrese, Eleonora Cocco, Christian Enzingher, Franz Fazekas, Massimo Filippi, Antonio Gallo, Ludwig Kappos, Maria Giovanna Marrosu, Vittorio Martinelli, Luca Prosperini, Maria Assunta Rocca, Alex Rovira, Till Sprenger, Maria Laura Stromillo, Gioacchino Tedeschi, Mar Tintorè, Carla Tortorella, Maria Trojano, Xavier Montalban, Carlo Pozzilli, Giancarlo Comi, Nicola De Stefano, MAGNIMS study group, Maria Pia Sormani, Claudio Gasperini, Marzia Romeo, Jordi Rio, Massimiliano Calabrese, Eleonora Cocco, Christian Enzingher, Franz Fazekas, Massimo Filippi, Antonio Gallo, Ludwig Kappos, Maria Giovanna Marrosu, Vittorio Martinelli, Luca Prosperini, Maria Assunta Rocca, Alex Rovira, Till Sprenger, Maria Laura Stromillo, Gioacchino Tedeschi, Mar Tintorè, Carla Tortorella, Maria Trojano, Xavier Montalban, Carlo Pozzilli, Giancarlo Comi, Nicola De Stefano, MP Sormani, C Gasperini, L Prosperini, M Romeo, J Rio, M Calabrese, E Cocco, C Enzinger, F Fazekas, M Filippi, A Gallo, L Kappos, MG Marrosu, V Martinelli, MA Rocca, A Rovira, T Sprenger, ML Stromillo, G Tedeschi, M Tintorè, C Tortorella, M Trojano, X Montalban, C Pozzilli, GC Comi, N De Stefano Neurology, 2016
Mitochondrial dysfunction in hereditary spastic paraparesis with mutations in DDHD1/SPG28 Andrea Mignarri, Anna Rubegni, Alessandra Tessa, Stefano Stefanucci, Alessandro Malandrini, Elena Cardaioli, Maria Chiara Meschini, Maria Laura Stromillo, Stefano Doccini, Antonio Federico, Filippo Maria Santorelli, Maria Teresa Dotti Journal of the Neurological Sciences, 2016
Efficacy and safety of intravenous immunoglobulin treatment in refractory Behcet’s disease with different organ involvement: A case series Israel Medical Association Journal, 2016
Prognostic biomarkers of IFNb therapy in multiple sclerosis patients Sergio E Baranzini, Lohith R Madireddy, Anne Cromer, Mauro D’Antonio, Lorenz Lehr, Manolo Beelke, Pierre Farmer, Marco Battaglini, Stacy J Caillier, Maria L Stromillo, Nicola De Stefano, Emmanuel Monnet, Bruce AC Cree Multiple Sclerosis, 2015
Effects of sapropterin on endothelium-dependent vasodilation in patients with CADASIL: A randomized controlled trial Renata De Maria, Jonica Campolo, Marina Frontali, Franco Taroni, Antonio Federico, Domenico Inzitari, Alessandra Tavani, Silvia Romano, Emanuele Puca, Francesco Orzi, Ada Francia, Caterina Mariotti, Chiara Tomasello, Maria Teresa Dotti, Maria Laura Stromillo, Leonardo Pantoni, Francesca Pescini, Raffaella Valenti, Claudio Pelucchi, Marina Parolini, Oberdan Parodi, Valentina Sedda, Elisabetta Spagnolo, Nicola De Stefano Stroke, 2014
Rapidly progressive neurodegeneration in a patient with familial hearing loss and heteroplasmic mitochondrial tRNASer(UCN) mutation mimicking a subacute progressive encephalitis Neurological Sciences, 2000
ASA pseudodeficiency associated with leukoencephalopathy and peripheral neuropathy: Coincidence or not? Neurological Sciences, 2000
