Rahul Pratap Singh

@gdgoenkauniversity.com

GD Goenka University

Rahul Pratap Singh
Dr. Rahul Pratap Singh is an expert in the area of Pharmaceutics (Cancer Nanotechnology) with a strong background in fabrication and characterization of pharmaceutical dosage forms and biomaterials using advanced scientific tools. His research focuses on cancer nanomedicine, protein, peptides and receptor binding, xenograft modeling, multi-functionalized nanomedicines to improve the safety profile of chemotherapeutics and therapeutic outcomes in cancer patients. He is teaching Biopharmaceutics, Pharmaceutical Engineering, Drug Delivery Systems at GD Goenka University (India).

EDUCATION

2005-2009 B. Pharm. (Pharmaceutical Sciences), Institute of Pharmacy, Bundelkhand University, Jhansi, India
2009-2011 M. Pharm. (Pharmaceutics), Institute of Pharmacy, Bundelkhand University, Jhansi, India
2013-2016 Ph.D. (Pharmaceutics), Department of Pharmacology, Institute of Medical Sciences,
Banaras Hindu University, Varanasi, India
2013-2015 Junior Research Fellow (JRF), Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
2015-2016 Senior Research Fellow (SRF), Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmacology, Toxicology and Pharmaceutics, Cancer Research, Pharmaceutical Science, Multidisciplinary
61

Scopus Publications

1809

Scholar Citations

22

Scholar h-index

30

Scholar i10-index

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

  • Folate-targeted, ethylenediaminetetraacetic acid-embedded, methotrexate-loaded albumin nanoparticles: Molecular modeling, design optimization, and in vitro anticancer …
    M Devi, P Goswami, B Koch, R Kataria, M Singh, RP Singh, S Arora, ...
    International Journal of Biological Macromolecules, 152373 , 2026
    2026
  • Development of a Reverse-Phase High-Performance Liquid Chromatography Method for Simultaneous Quantification of Tofacitinib Citrate and Berberine Chloride in Bulk, Injection …
    Monika, V Jhawat, M Chauhan, S Chauhan, Sonali, MK Singh, R Singh, ...
    Journal of Chromatographic Science 64 (4), bmag010 , 2026
    2026
  • Nanoparticle embedded dot matrix transdermal patches: a novel approach for targeted and controlled drug delivery in rheumatoid arthritis
    Devanshu, A Raj, RP Singh, M Gulia, S Arora, R Dutt, V Jhawat
    Inflammopharmacology, 1-20 , 2026
    2026
  • Hyaluronate-coated TPGS-g-chitosan nanoparticles for rheumatoid arthritis therapy: Pharmaceutical development, anti-inflammatory activities, and bone regeneration studies
    V Jhawat, S Chauhan, R Bhutani, G Kapoor, S Bharti, RP Singh
    International Journal of Biological Macromolecules, 149303 , 2026
    2026
    Citations: 4
  • Development and in-vitro optimization of telmisartan-curcumin solid dispersion nanoparticles for the management of diabetic nephropathy using DoE approach
    A Rawat, S Chauhan, RP Singh, Monika, S Gupta, V Jhawat
    Drug Development and Industrial Pharmacy 51 (10), 1244-1256 , 2025
    2025
    Citations: 1
  • DoE based development and optimization of ion sensitive in situ nanoemulgel containing bimatoprost for sustained ocular delivery
    M Singh, M Devi, RP Singh, V Jhawat
    International Journal of Biological Macromolecules, 147768 , 2025
    2025
    Citations: 1
  • Nanotechnology Based Topical Insulin Delivery System: Promising Role in Diabetic Wound Healing
    L Singh, A Bhakuni, Monika, RP Singh, S Arora, V Jhawat
    Wound Repair and Regeneration 33 (5), e70087 , 2025
    2025
    Citations: 2
  • An overview of hypertension: pathophysiology, risk factors, and modern management
    Deepshikha, P Mathur, Monika, V Jhawat, S Shekhar, R Dutt, V Garg, ...
    Current hypertension reviews 21 (2), 64-81 , 2025
    2025
    Citations: 12
  • Exploring Pneumonia: Understanding its Epidemiology, Deciphering Pathogenic Complexities, and Developing Advanced Diagnostic and Therapeutic Approaches
    J Verma, S Shekhar, Monika, M Chauhan, B Yadav, Sonali, RP Singh
    Current Respiratory Medicine Reviews , 2025
    2025
    Citations: 4
  • Formulation, Characterization, and In Vitro Analysis of a Curcumin-Loaded Lecithin-Coconut Oil-Based Emulgel for Enhanced Burn Management
    Vishal, S Dhandhi, Yeshna, M Singh, Monika, RP Singh, V Jhawat
    Recent Advances in Drug Delivery and Formulation , 2025
    2025
  • Nanotechnology in the chemotherapy medications
    RK Gupta, J Patra, RP Singh, AK Gupta
    IoT-WSN-DT Based Medical Systems and Nanotechnology for Smart Cancer Care, 79-90 , 2025
    2025
  • Nanotechnology for multimodal diagnosis and treatment mode
    M Jain, A Sarkar, RK Gupta, RP Singh, AK Gupta
    IoT-WSN-DT Based Medical Systems and Nanotechnology for Smart Cancer Care, 47-62 , 2025
    2025
  • Development and characterization of a gallic acid-infused topical emulgel for enhanced wound management: formulation and in vitro optimization
    S Dhandhi, S Chauhan, M Singh, RP Singh, V Jhawat
    RSC Pharmaceutics 2 (2), 333-341 , 2025
    2025
    Citations: 8
  • Current Trends and Challenges in Targeting Tumor Mitochondrial Glycolysis and Oxidative Phosphorylation Pathways for Cancer Therapy
    RP Singh, Sonali
    Current Protein & Peptide Science 26 (1), 2-5 , 2025
    2025
    Citations: 2
  • Synthesis and application of strontium-doped zinc ferrite nanomaterial in humidity sensing
    PR Tiwari, RP Singh, K Bharati, AC Yadav, B Bhardwaj, BC Yadav, ...
    Journal of the Indian Chemical Society 101 (12), 101439 , 2024
    2024
    Citations: 7
  • Preclinical pharmacology and pharmacokinetics of curcumin tagged cilostazol nanodispersion for the management of diabetic nephropathy in wister rat model
    A Rawat, S Chauhan, Monika, RP Singh, S Gupta, V Jhawat
    In Silico Pharmacology 12 (2), 81 , 2024
    2024
    Citations: 2
  • An overview of current progress and challenges in brain cancer therapy using advanced nanoparticles
    M Chauhan, RP Singh, Sonali, G Zia, S Shekhar, B Yadav, V Garg, R Dutt
    Recent Patents on Nanotechnology 18 (3), 295-304 , 2024
    2024
    Citations: 4
  • Synthesis of calcium doped zinc ferrite nanomaterial and its application as a humidity sensor
    PR Tiwari, RP Singh, K Bharati, AC Yadav, BC Yadav, A Singh, MP Singh, ...
    Journal of Dispersion Science and Technology 45 (11), 2155-2165 , 2024
    2024
    Citations: 8
  • Human immunodeficiency virus infection challenges: Current therapeutic limitations and strategies for improved management through long‐acting injectable formulation
    Tanushree, A Sharma, Monika, RP Singh, V Jhawat
    Reviews in Medical Virology 34 (4), e2563 , 2024
    2024
    Citations: 2
  • Topical delivery of insulin using novel organogel formulations: An approach for the management of diabetic wounds
    S Chauhan, V Jhawat, RP Singh, A Yadav
    Burns 50 (5), 1068-1082 , 2024
    2024
    Citations: 11

MOST CITED SCHOLAR PUBLICATIONS

  • Nanotheranostics: Emerging Strategies for Early Diagnosis and Therapy of Brain Cancer
    MSM Sonali, Matte Kasi Viswanadh, Rahul Pratap Singh, Poornima Agrawal ...
    Nanotheranostics 2 (1), 70-86. , 2018
    2018
    Citations: 175
  • Transferrin liposomes of docetaxel for brain-targeted cancer applications: formulation and brain theranostics
    Sonali, RP Singh, N Singh, G Sharma, MR Vijayakumar, B Koch, S Singh, ...
    Drug delivery 23 (4), 1261-1271 , 2016
    2016
    Citations: 153
  • Transferrin receptor-targeted vitamin E TPGS micelles for brain cancer therapy: preparation, characterization and brain distribution in rats
    Sonali, P Agrawal, RP Singh, CV Rajesh, S Singh, MR Vijayakumar, ...
    Drug delivery 23 (5), 1788-1798 , 2016
    2016
    Citations: 137
  • TPGS-chitosan cross-linked targeted nanoparticles for effective brain cancer therapy
    P Agrawal, Sonali, RP Singh, L Kumari, G Sharma, B Koch, CV Rajesh, ...
    Materials Science and Engineering: C 74, 167-176 , 2017
    2017
    Citations: 132
  • RGD-TPGS decorated theranostic liposomes for brain targeted delivery
    Sonali, RP Singh, G Sharma, L Kumari, B Koch, S Singh, S Bharti, ...
    Colloids and Surfaces B: Biointerfaces 147, 129-141 , 2016
    2016
    Citations: 117
  • Chitosan-folate decorated carbon nanotubes for site specific lung cancer delivery
    RP Singh, G Sharma, Sonali, S Singh, S Bharti, BL Pandey, B Koch, ...
    Materials Science and Engineering: C , 2017
    2017
    Citations: 110
  • Effects of transferrin conjugated multi-walled carbon nanotubes in lung cancer delivery
    RP Singh, G Sharma, Sonali, S Singh, SCU Patne, BL Pandey, B Koch, ...
    Materials Science and Engineering: C 67, 313-325 , 2016
    2016
    Citations: 89
  • Bioadhesive micelles of d-α-tocopherol polyethylene glycol succinate 1000: Synergism of chitosan and transferrin in targeted drug delivery
    P Agrawal, RP Singh, Sonali, G Sharma, AK Mehata, S Singh, CV Rajesh, ...
    Colloids and Surfaces B: Biointerfaces 152, 277-288 , 2017
    2017
    Citations: 85
  • Vitamin E TPGS conjugated carbon nanotubes improved efficacy of docetaxel with safety for lung cancer treatment
    RP Singh, G Sharma, Sonali, S Singh, M Kumar, BL Pandey, B Koch, ...
    Colloids and Surfaces B: Biointerfaces 141, 429-442 , 2016
    2016
    Citations: 80
  • RGD-decorated PLGA nanoparticles improved effectiveness and safety of cisplatin for lung cancer therapy
    B Yadav, M Chauhan, S Shekhar, A Kumar, AK Mehata, AK Nayak, R Dutt, ...
    International journal of pharmaceutics 633, 122587 , 2023
    2023
    Citations: 70
  • Transition from passive to active targeting of oral insulin nanomedicines: enhancement in bioavailability and glycemic control in diabetes
    D Kaklotar, P Agrawal, A Abdulla, RP Singh, Sonali, AK Mehata, S Singh, ...
    Nanomedicine 11 (11), 1465-1486 , 2016
    2016
    Citations: 63
  • Transferrin receptor targeted PLA-TPGS micelles improved efficacy and safety in docetaxel delivery
    RP Singh, G Sharma, Sonali, P Agrawal, BL Pandey, B Koch, MS Muthu
    International journal of biological macromolecules 83, 335-344 , 2016
    2016
    Citations: 61
  • Phytochemical investigation, isolation and characterization of betulin from bark of Betula utilis
    H Joshi, GK Saxena, V Singh, E Arya, RP Singh
    Journal of Pharmacognosy and Phytochemistry 2 (1) , 2013
    2013
    Citations: 48
  • Antidepressant activity of hydroalcoholic extract of Zingiber officinale
    RP Singh, R Jain, R Mishra, P Tiwari
    Int Res J Pharm 3 (2), 149-51 , 2012
    2012
    Citations: 42
  • Microfluidic assembly: an innovative tool for the encapsulation, protection, and controlled release of nutraceuticals
    H Liu, RP Singh, Z Zhang, X Han, Y Liu, L Hu
    Journal of agricultural and food chemistry 69 (10), 2936-2949 , 2021
    2021
    Citations: 37
  • Enhanced permeability and retention effect-focused tumor-targeted nanomedicines: latest trends, obstacles and future perspective
    S Shekhar, M Chauhan, Sonali, B Yadav, R Dutt, L Hu, MS Muthu, ...
    Nanomedicine 17 (18), 1213-1216 , 2022
    2022
    Citations: 33
  • AS1411 aptamer/RGD dual functionalized theranostic chitosan-PLGA nanoparticles for brain cancer treatment and imaging
    M Chauhan, S Shekhar, B Yadav, V Garg, R Dutt, AK Mehata, P Goswami, ...
    Biomaterials Advances 160, 213833 , 2024
    2024
    Citations: 32
  • Amomum subulatum Fruit Extract Mediated Green Synthesis of Silver and Copper Oxide Nanoparticles: Synthesis, Characterization, Antibacterial and Anticancer …
    S Dhir, R Dutt, RP Singh, M Chauhan, T Virmani, G Kumar, A Alhalmi, ...
    Processes 11 (9), 2698 , 2023
    2023
    Citations: 32
  • Sonali
    RP Singh, G Sharma
    Singh, S, 446-458 , 2016
    2016
    Citations: 31
  • Chitosan-alginate core-shell-corona shaped nanoparticles of dimethyl fumarate in orodispersible film to improve bioavailability in treatment of multiple sclerosis: Preparation …
    S Sinha, V Garg, Sonali, RP Singh, R Dutt
    Journal of Drug Delivery Science and Technology 64, 102645 , 2021
    2021
    Citations: 23

Publications

pharmacokinetics of curcumin tagged cilostazol nanodispersion for the management of diabetic nephropathy in wister rat model. In Silico Pharmacol. 2024 Sep 2;12(2):81. (Impact Factor 1.2)
2. Monika, Singh RP. Emerging trends and persistent challenges in nanomedicine for rheumatoid arthritis therapy. Curr Rheumatol Rev. 2024 Jul 26. (Impact Factor 1.2) [Corresponding Author]
3. Singh RP, Sonali. Current trends and challenges in targeting tumor mitochondrial glycolysis and oxidative phosphorylation pathways for cancer therapy. Curr Protein Pept Sci. 2024 Jul 3. doi: 10.2174/0113892037307636240612112408. (Impact Factor 1.9) [Corresponding Author]
4. Tanushree, Sharma A, Monika, Singh RP, Jhawat V. Human immunodeficiency virus infection challenges: Current therapeutic limitations and strategies for improved management through long-acting injectable formulation. Rev Med Virol. 2024 Jul;34(4):e2563. (Impact Factor 9)
5. Yadav B, Chauhan M, Sonali, Dinkar R, Shekhar S, Monika, Singh RP. In silico modeling, development, characterization, in-vitro cytotoxicity, pharmacokinetic, and toxicological studies of folate-receptor targeted micelles containing cisplatin and upconversion nanoparticles for lung cancer therapy. Materials Today Communications. 2024, 39: 109007. (Impact Factor 3.7) [Corresponding Author]
6. Chauhan M, Sonali, Shekhar S, Yadav B, Garg V, Dutt R, Mehata AK, Goswami P, Koch B, Muthu MS, Singh RP. AS1411 aptamer/RGD dual functionalized theranostic chitosan-PLGA nanopar

GRANT DETAILS

S. No. Title of Project Sponsoring Organization Period Date of Award Date of Completion Amount of Grant
(in Rs.) Role
1 Studies on therapeutic aspects of nucleic acid aptamer-grafted-RGD receptor targeted theranostic chitosan-PLGA nanoparticles for brain cancer diagnosis and treatment Science and Engineering
Research Board (SERB),
New Delhi 39 Months 13/7/20 12/10/23 41,00360/- Principal Investigator
2 Development and pharmacological evaluation of multifunctional receptor-targeted nano enabled-drug delivery systems for lung cancer therapy GD Goenka University, Gurugram 24
Months 24/12/21 23/12/23 1,70000/- Principal Investigator
Total Amount of Sanctioned Research Projects (in Rs.) 42,70,360/-

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

S. No. Name of the Teacher Patent Number Publication Date Title of the Patent Year of Publish Current Status
1 Suhani Sinha, Rahul Pratap Singh, Rohit Dutt 202311012541 A 17/03/2023 SUSTAINED RELEASE COMPOSITION OF DIMETHYL FUMURATE 2023 Published
2 Rahul Pratap Singh, Sonali, Mahima Chauhan, Saurabh Shekhar, Bhavna Yadav 202311027769 A 19/05/2023 D-ALPHA-TOCOPHERYL POLYETHYLENE GLYCOL 1000 SUCCINATE-AS1411 APTAMER (TPGS-AS1411) CONJUGATE AND SYNTHESIS THEREOF 2023 In examination
3 Rahul Pratap Singh, Mohit Sanduja, Neha Dagar, Mahima Chauhan, Sonali, Saurabh Shekhar, Krishan Tanwar, Vivek Saradhna 202311051960 A 15/09/2023 TRANSFERRIN-DECORATED CHITOSAN-ETHYLCELLULOSE NANOPARTICLES FOR
CONTROLLED AND TARGETED DELIVERY OF MYRICETIN FOR DIABETES MELLITUS 2023 In examination
4 Bhavna Yadav, Rahul Pratap Singh, Sonali, Mahima Chauhan, Saurabh Shekhar 202311053303 A 15/09/2023 INTEGRIN (AVß3) RECEPTOR-TARGETED PLGA NANOPARTICLES CONTAINING CISPLATIN AND UPCONVERSION NANOPARTICLES FOR LUNG CANCER 2023 In examination
5 Vikas Jhawat, Aruna Rawat, Rahul Pratap Singh 202311053308 A 15/09/2023 NANOPARTICULATE DRUG DELIVERY SYSTEM FOR THE MANAGEMENT OF DIABETIC NEPHROPATHY 2023 In examination
6 Sunita Chauhan, Vikas Jhawat, Rahul Pratap Singh 202311074943 A 24/11/2023 DOE ASSISTED DEVELOPMENT OF INSULIN LOADED TOPICAL ORGANOGEL FORMULATION FOR THE MANAGEMENT OF DIABETIC WOUND 2023 In examination
7 Vandana Garg, Preeti Garg, Jyoti, Kiran, Mahima Chauhan, Deependra Singh, Rohit Dutt, Rah

Industry, Institute, or Organisation Collaboration

Banaras Hindu University, Varanasi
Bundelkhand University, Jhansi

INDUSTRY EXPERIENCE

Mankind Research Centre, Manesar