Dr Preeti Anand

@iimt university

Associate Professor, IIMT COLLEGE OF MEDICAL SCIENCES PHARMACY
IIMT UNIVERSITY

Dr Preeti Anand


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https://researchid.co/preetianand

EDUCATION

Ph.D in Pharmaceutical Chemistry

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmacy, Pharmaceutical Science, Drug Discovery, Spectroscopy
2

Scopus Publications

108

Scholar Citations

2

Scholar h-index

1

Scholar i10-index

Scopus Publications

  • Phytochemical Profiling and Network Pharmacology-Based Evaluation of Aphrodisiac Potential of Mirabilis jalapa L. Root Extract
    Taufeek ., Anuj Kumar Sharma, Poonam Bhardwaj, Preeti Bala Anand, Namrata Singh, Afsha Khan, Dinesh Kumar Yadav, Arti Sinoria
    Natural Resources for Human Health, 2026
    <i>Mirabilis jalapa</i> L., (Gul Abbas or Four o’clock) is a traditional medicinal plant belonging to the family Nyctaginaceae. Originally native to tropical South America, particularly Peru, it has now become naturalized across various tropical and subtropical regions worldwide. Historically valued in folk medicine systems, <i>M. jalapa</i> has been utilized for its diverse therapeutic properties, including anti-inflammatory, diuretic, laxative, and aphrodisiac effects. The root of the plant, in particular, has garnered interest due to its high concentration of bioactive phytochemicals, making it a promising candidate for pharmacological research. This study focuses on evaluating the aphrodisiac potential of <i>M. jalapa</i> root extract using a multidisciplinary approach combining phytochemical screening, antioxidant evaluation, thin-layer chromatography, LC-MS-based metabolite profiling, and network pharmacology analysis. The methanolic extract of <i>M. jalapa</i> root demonstrated a significant yield and was found to contain key phytoconstituents such as flavonoids, phenolic acids, alkaloids, and glycoside compounds known for their roles in sexual health and vascular function. Antioxidant assays confirmed the extract’s strong radical scavenging ability, indicating potential protective effects against oxidative stress, a known contributor to sexual dysfunction. Liquid chromatography–mass spectrometry analysis identified several bioactive molecules like quercetin, rutin, ferulic acid, coumaric acid, isoquercitrin, apigenin etc. Furthermore, network pharmacology mapped the interactions between these compounds and genes (TP53, APP, IL1B, IGF1, CYP19A1, STAT3, TNF etc.) implicated in reproductive and hormonal pathways via regulation of nitric oxide production, hormones, and cell proliferation. Gene ontology and disease enrichment analyses reinforced the association with sexual health mechanisms. This integrated study scientifically validates the traditional claims of <i>M. jalapa</i> aphrodisiac potential and establishes a foundational basis for its future development as a safe and effective herbal therapeutic for sexual dysfunction.
  • Cinnamaldehyde analogs: Docking based optimization, COX-2 inhibitory in vivo and in vitro studies
    Vaishali M. Patil, Preeti Anand, Monika Bhardwaj, Neeraj Masand
    Current Drug Discovery Technologies, 2020
    Background: In the past decade CADD has emerged as a rational approach in drug development so with the help molecular docking approach we planned to perform virtual screening of the designed data set of Schiff bases of cinnamaldehyde. The research work will be helpful to put some light on the drug receptor interactions required for anti-inflammatory activity. Methods: For carrying out virtual screening of the developed cinnamaldehyde Schiff base data set, AutoDock 4.0 was used. The active hits identified through in silico screening were synthesized. Anti-inflammatory evaluation was carried out using Carrageenan-induced paw oedema method. Results: Compounds V2A44, V2A55, V2A76, V2A82, V2A119, V2A141 and V2A142 has shown highest binding energy (-4.84, -4.76, -4.59, -4.78, -4.74, -4.85 and -4.72 kcal/mol, respectively) and the binding interactions with amino acids namely, Phe478, Glu479, Lys492, Ala493, Asp497 and Ile498. Some of the analogs have shown significant activity and were comparable to Indomethacin (standard drug). Conclusion: Five new compounds have shown significant activity and the results obtained from in silico studies are parallel to those of in vivo studies.

RECENT SCHOLAR PUBLICATIONS

  • Cinnamaldehyde Analogs: Docking Based Optimization, COX-2 Inhibitory In Vivo and In Vitro Studies
    VM Patil, P Anand, M Bhardwaj, N Masand
    Current drug discovery technologies 17 (2), 154-165 , 2020
    2020
    Citations: 3
  • QSAR Study on Isatin Analogues Acting as HIV-Reverse Transcriptase Inhibitors
    VM Patil, N Masand, P Anand
    International Journal of Drug Design and Discovery 5 (1), 1249-1254 , 2014
    2014
  • Schiff bases: A review on biological insights
    P Anand, VM Patil, VK Sharma, RL Khosa, N Masand
    International Journal of Drug Design and Discovery 3 (3), 851-868 , 2012
    2012
    Citations: 103
  • Shiff bases: Areview on biological activities of Schiff base
    P Anand, VM Patil, VK Sharma, RL Khosa, N Masand
    International Journal on Drug Discovery 3, 851-866 , 2012
    2012
    Citations: 2

MOST CITED SCHOLAR PUBLICATIONS

  • Schiff bases: A review on biological insights
    P Anand, VM Patil, VK Sharma, RL Khosa, N Masand
    International Journal of Drug Design and Discovery 3 (3), 851-868 , 2012
    2012
    Citations: 103
  • Cinnamaldehyde Analogs: Docking Based Optimization, COX-2 Inhibitory In Vivo and In Vitro Studies
    VM Patil, P Anand, M Bhardwaj, N Masand
    Current drug discovery technologies 17 (2), 154-165 , 2020
    2020
    Citations: 3
  • Shiff bases: Areview on biological activities of Schiff base
    P Anand, VM Patil, VK Sharma, RL Khosa, N Masand
    International Journal on Drug Discovery 3, 851-866 , 2012
    2012
    Citations: 2
  • QSAR Study on Isatin Analogues Acting as HIV-Reverse Transcriptase Inhibitors
    VM Patil, N Masand, P Anand
    International Journal of Drug Design and Discovery 5 (1), 1249-1254 , 2014
    2014