Age-dependent differences in airway inflammation and function in severe uncontrolled asthma Jôse Mára de Brito, Natália de Souza Xavier Costa, Diogenes Seraphim Ferreira, Karina Pierantozzi Vergani, Regina Maria de Carvalho-Pinto, Luiz Vicente Ribeiro Ferreira da Silva-Filho, Rodrigo Abensur Athanazio, Joaquim Carlos Rodrigues, Thais Mauad, Miriam Cardoso Neves Eller Journal of Allergy and Clinical Immunology, 2026
Microbiological Analysis Following Periodontal Treatment in Individuals with Bronchiectasis Andreia La Selva, Ellen Sayuri Ando-Suguimoto, Ana Paula Mariano Santos Ginez, Tania Oppido Schalch, Renata Matalon Negreiros, Dione Kawamoto, Giuliana Giovinazzo Anselmo Ramos, Priscila Larcher Longo, Rodrigo Athanazio, Marcia Pinto Alves Mayer, Anna Carolina Ratto Tempestini Horliana Microorganisms, 2026 Periodontal status has been associated with infection in lung diseases such as chronic obstructive lung disease (COPD). However, evidence regarding its association with bronchiectasis remains limited, despite the shared clinical and pathophysiological characteristics between the two conditions. Therefore, the aim of the present study was to investigate whether periodontal treatment affects not only the microbiota of saliva but also that of sputum and nasal secretions in individuals with bronchiectasis. This single-center, parallel-group randomized controlled clinical trial included forty-nine individuals with bronchiectasis, who were randomly allocated using a predefined randomization sequence with allocation concealment to a conventional group (n = 26) submitted to mechanical periodontal treatment plus oral hygiene and a control group (n = 23) submitted to oral hygiene alone. Due to the nature of the intervention, participants and operators were not blinded. At the end of the study, all participants received periodontal treatment. The primary outcome was the quantitative assessment of Pseudomonas aeruginosa (P. aeruginosa), Staphylococcus aureus (S. aureus), and Porphyromonas gingivalis (P. gingivalis) in sputum. Secondary outcomes included the quantification of these microorganisms in saliva and nasal secretions, as well as clinical periodontal parameters and quality-of-life assessment. All variables were evaluated at baseline and three months after treatment. Results: Periodontal treatment improved gingival and plaque indices in the conventional group compared with the control group. However, no significant differences were observed in sputum samples for any of the microorganisms analyzed, suggesting no measurable effect on bacterial levels in the lower airways within the study period. At the end of the experimental period, levels of P. aeruginosa and P. gingivalis decreased in nasal secretions, and levels of P. aeruginosa decreased in saliva in the conventional group but not the control group. No significant differences were found in S. aureus levels between groups or overtime. Also, no significant differences in total OHIP-14 scores were observed between groups. In conclusion, periodontal treatment was associated with reductions in P. aeruginosa in nasal secretions and saliva, and P. gingivalis in nasal secretions, in individuals with bronchiectasis and periodontitis. Periodontal treatment improved gingival and plaque indices in the conventional group compared with the control group. However, no significant differences were observed in sputum samples for any of the microorganisms analyzed, suggesting no measurable effect on bacterial levels in the lower airways within the study period. At the end of the experimental period, levels of P. aeruginosa and P. gingivalis decreased in nasal secretions, and levels of P. aeruginosa decreased in saliva in the conventional group but not the control group. No significant differences were found in S. aureus levels between groups or overtime. Also, no significant differences in total OHIP-14 scores were observed between groups.
Opportunistic thoracic CT scan over bone densitometry in CF care: Is it possible to screen for osteoporosis using a CT scan? Cynthia Rocha Dullius, Marcelo Tadday Rodrigues, Gabriele Carra Forte, Rubens Gabriel Andrade Feijó, Rodrigo Abensur Athanazio, Bruno Hochhegger, Leonardo Araújo Pinto Respiratory Medicine, 2026 INTRODUCTION: Cystic fibrosis (CF) is an autosomal recessive disease that alters ionic transport in the body's secretions, including those of the lung mucosa, and is the most common hereditary respiratory disease in the Western world. One of the causes of morbidity and decreased quality of life in patients with CF is osteoporosis, which is currently assessed by bone densitometry. METHODS: bi-centric, cross-sectional, retrospective study, reviewing data contained in the medical records of patients with cystic fibrosis participants who were treated at 2 CF reference centers, and reanalysis of chest tomography scans performed annually during checkup, in comparison with their bone densitometry measurements from the same period. RESULTS: A total of 73 CF patients were evaluated. Patients with DXA-defined osteoporosis showed significantly lower HU values. Using 215HU as the cutoff, we obtained 83% sensitivity and 68% specificity for osteoporosis. Area under the ROC curve was 0.86 using analyses of T10 to T12 vertebrae. CONCLUSIONS: Chest computed tomography may serve as an opportunistic screening for identifying patients with cystic fibrosis at increased risk of low bone mineral density, particularly when CT examinations are already being performed for other clinical reasons.
Healthcare worker views on antimicrobial resistance in chronic respiratory disease Sachin Ananth, Adekunle O. Adeoti, Animesh Ray, Peter G. Middleton, Miquel Ekkelenkamp, Stephanie Thee, Anand Shah, , Abayomi Fadeyi, Abdoul Risgou Ouedraogo, Addishiwot Melesse Seminew, Adele Roux, Adnan Zafar, Aizhamal Tabyshova, Aleksandra Barac, Alex Gileles-Hillel, Alexander Kiefer, Alexandra Hebestreit, Alice Tebboth, Amelia Shoemark, Ana Machado, André Santos-Silva, Andrea Gramegna, Andriy Serediuk, Angela Tramontano, Anna Salina, Annie Navarro Rolon, Anoop Prakash, António Gonçalves, Aran Singanayagam, Arun H. Mahadevaiah, Asha Muthusami, Avinash Aujayeb, Ayşe Önal Aral, Barbara Kahl, Ben Huggon, Bohdana Pereviznyk, Braulio Chevalier Vidal, Bukar Bakki, Bulent Karadag, Bushra Ahmed, Calmés Doriane, Cao Pham Ha Giang, Carmelo Sofia, Catia Cilloniz, Cátia Paixão, Charl Verwey, Charles Feldman, Charlotte Carter, Chiara Premuda, Chizoba Efobi, Clementine Fraser, Corentine Alauzet, Damir Vukoja, Danial Naqvi, Daniela Maria Cirillo, Dareen Marghlani, Daryl Butler, David Abelson, David Stickells, Deepa Kumari Shrestha, Deepa Patel, Devesh J. Dhasmana, Devi Jyoti Dash, Diana Ergle, Dilara Ömer Topçu, Dominic L. Sykes, Dorina Rama Esendagli, Dumitras Tatiana, Efthymia Papadopoulou, Elsa Branco, Eva Van Braeckel, Evans Frexon Liseki, Evie Alexandra Robson, Fapohunda Temitope Victoria, Maria de Fatima Magalhaes Gonzaga, Felix Bongomin, Felix C. Ringshausen, Felix Manyeruke, Freddy Frost, Friso de Weert, Garante Carmela Melania, Garry McDonald, Geneviève Héry-Arnaud, Giancarlo De Leo, Gina Amanda, Gioia Piatti, Giovanna Manfredini, Grillon Antoine, Guillaume Thouvenin, Gunar Günther, Hélida Conceição Cavalcante Torres, Helle Krogh Johansen, Henny Azmanov, Hussein Elkhayat, Hussein Mohamed Ahmed, Ian Clifton, Ignacio Martin-Loeches, Indiane Putri Ningtias, Ines Azevedo, Inge Muylle, Irfan Shafiq, Iwein Gyselinck, Joel Israëls, Jaber S. Alqahtani, James Ayodele Ogunmodede, Jamil Jubrail, Jatin G. Nagar, Jeanne-Marie Perotin, Jimstan Periselneris, Jo Congleton, Johnmary T. Arinze, Joseph Fadare, Joy Eze, Justus Simba, Kartik Kumar, Katharine Hurt, Kay Roy, Koen Verbeke, Kristi Reveli, Krystyna Poplawska, Kwok Wang Chun, Lawani Olufemi Ademola, Leidy Prada, Leonardo Gori, Letizia Corinna Morlacchi, Linda Aprillia Rolobessy, Lisa Nwankwo, Lorenzo Carriera, Loskova Elena Vladimirovna, Lydia Finney, Mai S. Elsheikh, Malvina Hoxha, Marcos I. Restrepo, Margarete Lopes Teixeira Arrais, Maria Gabrovska, Maria Grazia Cagnazzo, Maria Joana Catarata, Marialuisa Bocchino, Mario Di Stasio, Marrah Lachowicz-Scroggins, Mary Wambura, Matlawene John Mpe, Matthew Pavitt, Mattia Nigro, Melanie Sue Collins, Michelle Uno, Miguel Gallego, Milind Sathe, Mine Kalyoncu, Mohammad Abdullah, Mona Lichtblau, Mukesh Singh, Mwanaada Ahmad Kilima, Natalie Lorent, Nazanin Farahbakhsh, Ngoc Duong-Minh, Nguyen Pham Anh Hong, Nicola Ronan, Nicola Travaglini, Nilotpal Bhattacherjee, Nilüfer Aylin Acet Öztürk, Nina Ratu Nur Kharima, Niranjan Chandramal Lehupe Bandarage, Nishith Kumar, Nita Corry Agustine Nias, Nwosu Nnamdi Ikechukwu, Oleksandr Mazulov, Olga Bielousova, Olga Mashedi, Omer Elneima, Ophir Bar-On, Özge Aydın Güçlü, Pabitra Banerjee, Pavel Yordanov, Pedro Gonçalo Ferreira, Pieter Goeminne, Prakash Mohan Jeena, Priti Kenia, Priyanka Poda, Pujan H. Patel, Rafiuk Cosmos Yakubu, Rameesha Khalid, Ranganath Thippanahalli Ganga, Rasheedat Mobolaji Ibraheem, Ravini Karunatillake, Rawya Ahmed, Ricardo Figueiredo, Richard Hewitt, Ridzuan Mohsin, Rodrigo Abensur Athanazio, Rohit Kumar, Rosanel Amaro, SRaghul Raj, Sabi Hippolyte, Sabrine Louhaichi, Salvatore Tripodi, Sandra Rovira-Amigo, Sanem Eryılmaz Polat, Sara Manti, Sarah Loof, Saurabh Singh, Sega Pathmanathan, Serena Romeo, Shirley V. Cuan-Escobar, Silvia Castillo-Corullón, Sinchuk Nataliya, Siobhan B. Carr, Siyu Dai, Snezhina Lazova, Sonja van Scheijen, Sophie Gohy, Soumitra Mondal, Srimali Wijesundara, Stavros Tryfon, Stefano Aliberti, Stephan Illing, Suleiman Sherifat Tinuke, Sumudu Withanage, Susanne Hämmerling, Tariq Qadeer, Tavs Qvist, Tehreem Ahmad, Temitope Victoria Fapohunda, Thomas Guillard, Till Othmer, Tim Felton, Tony De Soyza, Toufic Chaaban, Vanessa Kahr, Vânia Fernandes, Vera Clérigo, Veroniek Saegeman, Vikram Damaraju, Vipula Rasanga Bataduwaarachchi, Vivek Gundappa, Yannick Vande Weygaerde Antimicrobial Resistance and Infection Control, 2025 Background and objective Antimicrobial resistance (AMR) is a global crisis, however, relatively little is known regarding its impact in chronic respiratory disease and the specific challenges faced by healthcare workers across the world in this field. We aimed to assess global healthcare worker views on the challenges they face regarding AMR in chronic respiratory disease. Methods An online survey was sent to healthcare workers globally working in chronic respiratory disease through a European Respiratory Society clinical research collaboration (AMR-Lung) focussed on AMR in chronic lung disease. Responses from different geographic regions were analysed. Results 279 responses were received across 60 countries. 54.5% of respondents encountered AMR in chronic respiratory disease weekly. There were differences in perceived high-priority diseases and species with AMR burden between Europe, Asia and Africa. 76.4% of respondents thought that inappropriate antimicrobial prescribing in chronic respiratory disease was common. However, only 43.4% of respondents thought that there were adequate antimicrobial stewardship programmes in their area for chronic respiratory disease, with limited availability in outpatient (29.0%) and ambulatory settings (24.7%). Developing rapid diagnostics for antimicrobial susceptibility (59.5%) was perceived to be the most common challenge in implementing antimicrobial stewardship, with an improved understanding of regional epidemiology of AMR strains the most important factor to improve outcome (55.2%). Conclusions AMR has significant perceived burden in chronic respiratory disease by healthcare professionals globally. However, current implementation of antimicrobial stewardship is limited, with significant challenges related to the availability of rapid diagnostics and understanding of regional epidemiology of AMR strains.
Regional challenges to optimize the management of patients with severe asthma type 2 inflammation: a Delphi consensus in seven countries Liam G. Heaney, Desiree Larenas-Linnemann, Riyad Al-Lehebi, Rodrigo Athanazio, Paulina Barria, Abraham Ali Munive, Daniel Colodenco, Anahi Yañez, Libardo Jimenez, Marcia M. Pizzichini, Deepak Talwar, Emilio Pizzichini, Gur Levy, Maria E. Laucho-Contreras Journal of Asthma, 2025 Objective:Severe asthma burdens patients and presents clinical management challenges for healthcare professionals. Biologics are crucial interventions for severe type two (T2) patients with high eosinophil counts. We conducted a Delphi consensus in seven developing or typically underrepresented countries to understand expert agreement on managing severe asthma with type two (T2) inflammation. Methods:The study comprised two online survey rounds and a participant meeting, involving 21 and 20 respiratory experts in the first and second survey, respectively. We developed a 70-statement questionnaire after literature review. Responses were recorded on a Likert scale (0-9) with 75% consensus threshold. Results:Consensus was reached on 37/60 closed-ended questions, including subtypes, in survey-1 and 20/47 closed-ended questions in survey-2. 95% of participants agreed on biomarker use for biologic treatment selection. 100% agreed timely biologic treatment leads to improvement in patients with severe asthma and an eosinophilic phenotype. 90% agreed to avoid maintenance oral corticosteroids (OCS) and start biologic therapy directly. Experts defined clinical remission on treatment as no exacerbations, no OCS use, Asthma Control Questionnaire (ACQ)-5 score < 1.5, and lung function optimization (forced expiratory volume in one second [FEV1] ≥ 80% of predicted or pre-bronchodilator FEV1 increase ≥ 100 mL from baseline). In survey-1, 81% agreed these outcomes are achievable in practice. All referral statements achieved consensus. Conclusions:This Delphi study focused on understanding patients with severe asthma and T2 inflammation in developing/underrepresented countries. Appropriately utilizing biomarkers, timely treatment interventions for best outcomes, expert consensus on clinical remission, and referral are crucial for improving patient management.
Depression and anxiety in adolescents with cystic fibrosis in Brazil: prevalence, stability over time, and relationship with treatment adherence Tatiana Rozov1, Marcos Tadeu Nolasco da Silva2, Maria Ângela Gonçalves Oliveira Ribeiro2, Neiva Damaceno3, Maria Angelica Pinheiro Santos Santana4, Paulo Jose Cauduro Marostica5, Roberta de Cássia Nunes Cruz Melotti6, Valeria de Carvalho Martins7, Carlos Antônio Riedi8, Edna Lucia Santos de Souza9, Norberto Ludwig Neto10, Rodrigo Abensur Athanazio1, Francyelly Wisnievski Yamamoto11, Lusmaia Damaceno Camargo Costa12, Sonia Mayumi Chiba13, Izabela Sad14, José Dirceu Ribeiro2, Alexandra L. Quittner15, Brazilian Anxiety, Depression, Adherence Study Group (BADAS)1 Jornal Brasileiro De Pneumologia, 2025 Objective: Depression and anxiety have been documented in people with cystic fibrosis (CF), jeopardizing treatment adherence. To date, no studies have assessed the prevalence of psychosocial issues in adolescents with CF in Brazil. We sought to assess the prevalence of depression and anxiety in adolescents with CF in Brazil, as well as the impact of depression and anxiety on treatment adherence. Methods: This was a multicenter, prospective, observational, longitudinal study conducted between 2017 and 2019 at 14 CF referral centers in Brazil. We used standardized tools such as the nine-item Patient Health Questionnaire (for depression), the seven-item Generalized Anxiety Disorder scale (for anxiety), and the eight-item Morisky Medication Adherence Scale (for treatment adherence) in order to collect data on 218 CF patients at two different time points. Results: The prevalence of depression was 19.1% at time point 1 and 15.4% at time point 2. The prevalence of anxiety was 19.1% at time point 1 and 18.0% at time point 2. Depression and anxiety were significantly higher in female patients and lower in those who underwent home physiotherapy or had psychological support. Significant correlations were found between depression and anxiety at both time points, the associations being strongest at time point 1 (r = 0.68; p < 0.001). Most (66.7%) of the study participants reported low adherence to treatment, and the remainder reported either average adherence (in 28%) or high adherence (in 5.3%). Depression and anxiety showed inverse correlations with treatment adherence. Conclusions: The prevalence of depression and anxiety in adolescents with CF in Brazil appears to be similar to that reported in other countries, being higher in females and lower in those undergoing home physiotherapy or receiving psychological care. Depression and anxiety appear to correlate with lower treatment adherence. Treating psychosocial issues may effectively improve rates of treatment adherence in adolescents with CF.
Impact of COVID-19 infection on lung function and nutritional status amongst individuals with cystic fibrosis: A global cohort study Julie Semenchuk, Yumi Naito, Susan C. Charman, Siobhán B Carr, Stephanie Y. Cheng, Bruce C. Marshall, Albert Faro, Alexander Elbert, Hector H. Gutierrez, Christopher H. Goss, Bulent Karadag, Pierre-Régis Burgel, Carla Colombo, Marco Salvatore, Rita Padoan, Géraldine Daneau, Satenik Harutyunyan, Nataliya Kashirskaya, Laura Kirwan, Peter G Middleton, Rasa Ruseckaite, Isabelle de Monestrol, Lutz Naehrlich, Pedro Mondejar-Lopez, Andreas Jung, Jacqui van Rens, Egil Bakkeheim, Annalisa Orenti, Domenique Zomer-van Ommen, Luiz Vicente RF da Silva-Filho, Flavia Fonseca Fernandes, Marco Zampoli, Anne L. Stephenson, Irena Kasmi, Ouardia Drali, Sabine Burghart, Andrea Lakatos-Krepcik, Johannes Eder, Peter Jaksch, Katharina Kainz, Margit Kallinger, Alexander Leitner, Marta Mozdzen, Andreas Pfleger, Sabine Renner, Martin Stadlinger, Christina Thir, Emil Nuriyev, Hedwige Boboli, Elke De Wachter, Lieven Dupont, Sophie Gohy, Laurence Hanssens, Christiane Knoop, Elise Lammertyn, Vicky Nowé, Jessica Pirson, Matthieu Thimmesch, Eva Van Braeckel, Kim Van Hoorenbeeck, Eef Vanderhelst, Eduardo Piacentini Filho, Rodrigo Abensur Athanazio, Valéria de Carvalho Martins, Marta Cristina Duarte, Luciana de Freitas Velloso Monte, Marcelo Bicalho de Fuccio, Adriana de Siqueira Carvalho Knabben, Roberta Melloti, Daniela Gois Meneses, Guergana Petrova, Duška Tješić-Drinković, Andrea Vukić Dugac, Ivan Bambir, Panayiotis Yiallouros, Alena Bilkova, Pavel Drevinek, Milan Macek, Hanne Vebert Olesen, Tania Pressler, Eman Mahmoud Fouda, Samya Nasr, Abate Yeshidinber Weldetsadik, Montaha Al-iede, Olzhas Abdrakhmanov, Harriet Corvol, Lydie Lemonnier-Videau, Michel Abely, Carole Bailly Piccini, Chantal Belleguic, Tiphaine Bihouee, Yves Billon, Stéphanie Bui, Boubou Camara, Marie-Christine Cheraud, Raphael Chiron, Emmanuelle Coirier Duet, Laure Cosson, Marie-Laure Dalphin, Isabelle Danner Boucher, Sandra De Miranda, Eric Deneuville, Jean-Christophe Dubus, Isabelle Durieu, Ralph Epaud, Michèle Gerardin, Dominique Grenet, Véronique Houdouin, Frédéric Huet, Kanaan Reem, Romain Kessler, Jeanne Languepin, Muriel Laurans, Sylvie Leroy, Cathie Llerena, Julie Macey, Julie Mankikian, Christophe Marguet, Clémence Martin, Laurent Mely, Marie Mittaine, Marlène Murris-Espin, Caroline Perisson, Anne Prevotat, Sophie Ramel, Cinthia Rames, Philippe Reix, Marine Revillon, Martine Reynaud-Gaubert, Bénédicte Richaud-Thiriez, Jean-Luc Rittie, Manuëla Scalbert-Dujardin, Isabelle Sermet-Gaudelus, Véronique Storni, Aurélie Tatopoulos, Guillaume Thouvenin, Françoise Troussier, Laurence Weiss, Nathalie Wizla, Eva-Susanne Behl, Folke Brinkmann, Martin Claßen, Ute Graepler-Mainka, Matthias Griese, Armin Grübl, Jutta Hammermann, Helge Hebestreit, Andrea Heinzmann, Alexander Herz, Alexander Kiefer, Birte Kinder, Holger Köster, Stefan Kuhnert, Jochen Mainz, Angelika Mayer, Susanne Naehrig, Tim Niehues, Thomas Nüßlein, Krystyna Poplawska, Felix Ringshausen, Markus Rose, Josef Rosenecker, Renate Ruppel, Anette Scharschinger, Christian Schropp, Carsten Schwarz, Christina Smaczny, Olaf Sommerburg, Sivagurunathan Sutharsan, Simone Stolz, Wolfgang Thomas, Sabine Wege, Britta Welzenbach, Bettina Wollschläger, Filia Diamantea, Elpis Hatziagorou, Katerina Manika, Des Cox, Basil Elnazir, Godfrey Fletcher, Cedric Gunaratnam, Edward F. McKone, Barry J. Plant, Malena Cohen-Cymberknoh, Michal Gur, Galit Livnat, Meir Mei-Zahav, Annalisa Amato, Gianluca Ferrari, Raffaele Badolato, Piercarlo Poli, Fiorella Battistini, Valentina Donati, Elisabetta Bignamini, Anna Folino, Vincenzo Carnovale, Carlo Castellani, Rosaria Casciaro, Giuseppe Cimino, Marco Cipolli, Francesca Lucca, Mirella Collura, Francesca Ficili, Valeria Daccò, Vanessa Gagliano, Giovanna Pizzamiglio, Valeria Mencarini, Nicola Palladino, Salvatore Leonardi, Novella Rotolo, Maria Cristina Lucanto, Ester Quattromano, Vincenzina Lucidi, Fabio Majo, Federico Alghisi, Fabiana Ciciriello, Antonio Manca, Giuseppina Leonetti, Massimo Maschio, Barbara Messore, Stefano Pantano, Giovanna Pisi, Cinzia Spaggiari, Valeria Raia, Caterina Laezza, Mirco Ros, Donatello Salvatore, Giovanni Taccetti, Michela Francalanci, Pamela Vitullo, Anna Zolin, Elina Aleksejeva, Kestutis Malakauskas, Valdone Misevičiene, Anna-Maria Charatsi, Hélène De la Barrière, Josje Altenburg, Michiel Bannier, Harry Heijerman, Hettie Janssens, Gerard Koppelman, Renske van der Meer, Peter Merkus, Marianne Nuijsink, Suzanne Terheggen, Hester van der Vaart, Geert-Jan Wesseling, Karin de Winter, Ivana Arnaudova Danevska, Tatjana Jakovska Maretti, Stojka Fustik, Daria Dziecichowicz-Latała, Irena Wojsyk-Banaszak, Lukasz Wozniacki, Adelina Amorim, Ana Sofia Araújo Santos, Susana Castanhinha, Fernanda Gamboa, Teresa Reis Silva, Fabienne Gonçalves, Luísa Pereira, Ioana Ciuca, Sónia Silva, Szabo Csilla-Enikö, Iustina Stan, Elena Amelina, Evgeniya Boitсova, Anastasia Chernyavskaya, Yuliya Gorinova, Stanislav Krasovskiy, Maria Mukhina, Victoria Sherman, Olga Simonova, Elena Kondratyeva, Eva Bérešová, Nina Bližnáková, Hana Kayserová, Barbara Salobir, Julij Šelb, Uroš Krivec, Antonio José Aguilar Fernandez, Antonio Alvarez Fernàndez, Félix Baranda García, Marina Blanco Aparicio, Silvia Castillo Corullón, Isidoro Cortell-Aznar, Inés Pérez, Jordi Costa i Colomer, María Cols Roig, Isabel Delgado Pecellín, Layla Diab Cáceres, Carmen Luna Paredes, Silvia Gartner, José Ramón Gutiérrez Martínez, Inés Herrero Labarga, Rosa Maria Girón-Moreno, Esperanza Jiménez Nogueira, Adelaida Lamas Ferreiro, Alejandro López Neyra, Enrique Blitz Castro, Laura Moreno Galarraga, Carlos Martin de Vincente, Silvia Merlos Navarro, Rosa Nieto-Royo, Casilda Olveira Fuster, Maria Dolores Pastor, Estela Pérez-Ruiz, Concepción Prados-Sánchez, Isabel Ramos Cancelo, Marta Ruiz de Valbuena, José R. Villa Asensi, Veronica Sanz Santiago, Patricia Fernández García, Reem Mustafa Tawfeeq, Adrienn Banki, Marita Gilljam, Christina Krantz, Ulrika Lindberg, Anders Lindblad, Christian Clarenbach, Carolin Steinack, René Hage, Macé Schuurmans, Reta Fischer, Rachel Kusche, Isabelle Rochat, Macé Schuurmans, Anna-Lena Walter, Harutai Kamalaporn, Samia Hamouda, Dilber Ademhan Tural, Ugur Ozcelik, Pelin Asfuroğlu, Tuğba Şişmanlar Eyüboğlu, Ayse Tana Aslan, Ayşen Bingöl, Nazan Çobanoğlu, Gizem Ozcan, Deniz Dogru, Yasemin Gökdemir, Mehmet KÖSE, Sevgi Pekcan, Rebecca Cosgriff Journal of Cystic Fibrosis, 2024 <h2>Abstract</h2><h3>Background</h3> Factors associated with severe COVID-19 infection have been identified; however, the impact of infection on longer-term outcomes is unclear. The objective of this study was to examine the impact of COVID-19 infection on the trajectory of lung function and nutritional status in people with cystic fibrosis (pwCF). <h3>Methods</h3> This is a retrospective global cohort study of pwCF who had confirmed COVID-19 infection diagnosed between January 1, 2020 and December 31, 2021. Forced expiratory volume in one second percent predicted (ppFEV<sub>1</sub>) and body mass index (BMI) twelve months prior to and following a diagnosis of COVID-19 were recorded. Change in mean ppFEV<sub>1</sub> and BMI were compared using a <i>t</i>-test. A linear mixed-effects model was used to estimate change over time and to compare the rate of change before and after infection. <h3>Results</h3> A total of 6,500 cases of COVID-19 in pwCF from 33 countries were included for analysis. The mean difference in ppFEV<sub>1</sub> pre- and post-infection was 1.4 %, (95 % CI 1.1, 1.7). In those not on modulators, the difference in rate of change pre- and post-infection was 1.34 %, (95 % CI -0.88, 3.56) per year (<i>p</i> = 0.24) and -0.74 % (-1.89, 0.41) per year (<i>p</i> = 0.21) for those on elexacaftor/tezacaftor/ivacaftor. No clinically significant change was noted in BMI or BMI percentile before and after COVID-19 infection. <h3>Conclusions</h3> No clinically meaningful impact on lung function and BMI trajectory in the year following infection with COVID-19 was identified. This work highlights the ability of the global CF community to unify and address critical issues facing pwCF.
Rate of severe exacerbations, healthcare resource utilisation and clinical outcomes in patients with COPD in low-income and middle-income countries: results from the EXACOS International Study Rodrigo Abensur Athanazio, Laura Bernal Villada, Sergey N Avdeev, Hao-Chien Wang, Alejandra Ramírez-Venegas, Martín Sivori, Jorge Dreyse, Manuel Pacheco, Sin Kit Man, Lorena Noriega-Aguirre, Hisham Farouk BMJ Open Respiratory Research, 2024 IntroductionTheEXAcerbations ofChronic obstructive lung disease (COPD) and theirOutcomeS(EXACOS) International Study aimed to quantify the rate of severe exacerbations and examine healthcare resource utilisation (HCRU) and clinical outcomes in patients with COPD from low-income and middle-income countries.MethodsEXACOS International was an observational, cross-sectional study with retrospective data collection from medical records for a period of up to 5 years. Data were collected from 12 countries: Argentina, Brazil, Chile, Colombia, Costa Rica, Dominican Republic, Guatemala, Hong Kong, Mexico, Panama, Russia and Taiwan. The study population comprised patients ≥40 years of age with COPD. Outcomes/variables included the prevalence of severe exacerbations, the annual rate of severe exacerbations and time between severe exacerbations; change in lung function over time (measured by the forced expiratory volume in 1 s (FEV1)); peripheral blood eosinophil counts (BECs) and the prevalence of comorbidities; treatment patterns; and HCRU.ResultsIn total, 1702 patients were included in the study. The study population had a mean age of 69.7 years, with 69.4% males, and a mean body mass index of 26.4 kg/m2. The mean annual prevalence of severe exacerbations was 20.1%, and 48.4% of patients experienced ≥1 severe exacerbation during the 5-year study period. As the number of severe exacerbations increased, the interval between successive exacerbations decreased. A statistically significant decrease in mean (SD) FEV1from baseline to post-baseline was observed in patients with ≥1 severe exacerbation (1.23 (0.51) to 1.13 (0.52) L; p=0.0000). Mean BEC was 0.198 x109cells/L, with 64.7% of patients having a BEC ≥0.1 x109 cells/L and 21.3% having a BEC ≥0.3 x109 cells/L. The most common comorbidity was hypertension (58.3%). An increasing number of severe exacerbations per year was associated with greater HCRU.DiscussionThe findings presented here indicate that effective treatment strategies to prevent severe exacerbations in patients with COPD remain a significant unmet need in low-income and middle-income countries.
Use of elexacaftor+tezacaftor+ivacaftor in individuals with cystic fibrosis and at least one F508del allele: a systematic review and meta-analysis Luiz Vicente Ribeiro Ferreira da Silva Filho1, Rodrigo Abensur Athanazio2, Carolina Rodrigues Tonon3, Juliana Carvalho Ferreira2, Suzana Erico Tanni3 Jornal Brasileiro De Pneumologia, 2024 Objective: To evaluate the effect of treatment with the combination of three cystic fibrosis transmembrane conductance regulator (CFTR) modulators-elexacaftor+tezacaftor+ivacaftor (ETI)-on important clinical endpoints in individuals with cystic fibrosis. Methods: This was a systematic review and meta-analysis of randomized clinical trials that compared the use of ETI in individuals with CF and at least one F508del allele with that of placebo or with an active comparator such as other combinations of CFTR modulators, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations and the Patients of interest, Intervention to be studied, Comparison of interventions, and Outcome of interest (PICO) methodology. We searched the following databases: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov from their inception to December 26th, 2022. The risk of bias was assessed using the Cochrane risk-of-bias tool, and the quality of evidence was based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Results: We retrieved 54 studies in the primary search. Of these, 6 met the inclusion criteria and were analyzed (1,127 patients; 577 and 550 in the intervention and control groups, respectively). The meta-analysis revealed that the use of ETI increased FEV1% [risk difference (RD), +10.47%; 95% CI, 6.88-14.06], reduced the number of acute pulmonary exacerbations (RD, -0.16; 95% CI, -0.28 to -0.04), and improved quality of life (RD, +14.93; 95% CI, 9.98-19.89) and BMI (RD, +1.07 kg/m2; 95% CI, 0.90-1.25). Adverse events did not differ between groups (RD, -0.03; 95% CI, -0.08 to 0.01), and none of the studies reported deaths. Conclusions: Our findings demonstrate that ETI treatment substantially improves clinically significant, patient-centered outcomes.
Rheumatoid arthritis-associated airway disease: longitudinal pulmonary function behavior Maria Laura Bertozo Sabbag1, Camila de Assis Molina1, Márcio Valente Yamada Sawamura2, Karina Bonfiglioli3, Ana Cristina Medeiros-Ribeiro3, Alisson Pugliesi4, Renato Hideo Nakagawa5, Fabio Eiji Arimura6, Rodrigo Abensur Athanazio6, Ronaldo Adib Kairalla6, Bruno Guedes Baldi6, Leticia Kawano-Dourado6, 7 Jornal Brasileiro De Pneumologia, 2024
A BEAT-PCD consensus statement: a core outcome set for pulmonary disease interventions in primary ciliary dyskinesia Renate Kos, Myrofora Goutaki, Helene E. Kobbernagel, Bruna Rubbo, Amelia Shoemark, Stefano Aliberti, Josje Altenburg, Pinelopi Anagnostopoulou, Rodrigo A. Athanazio, Nicole Beydon, Sharon D. Dell, Nagehan Emiralioglu, Thomas W. Ferkol, Michael R. Loebinger, Natalie Lorent, Bernard Maître, June Marthin, Lucy C. Morgan, Kim G. Nielsen, Felix C. Ringshausen, Michal Shteinberg, Harm A.W.M. Tiddens, Anke H. Maitland-Van der Zee, James D. Chalmers, Jane S.A. Lucas, Eric G. Haarman Erj Open Research, 2024
Analyses of 1236 genotyped primary ciliary dyskinesia individuals identify regional clusters of distinct DNA variants and significant genotype–phenotype correlations Johanna Raidt, Sarah Riepenhausen, Petra Pennekamp, Heike Olbrich, Israel Amirav, Rodrigo A. Athanazio, Micha Aviram, Juan E. Balinotti, Ophir Bar-On, Sebastian F.N. Bode, Mieke Boon, Melissa Borrelli, Siobhan B. Carr, Suzanne Crowley, Eleonora Dehlink, Sandra Diepenhorst, Peter Durdik, Bernd Dworniczak, Nagehan Emiralioğlu, Ela Erdem, Rossella Fonnesu, Serena Gracci, Jörg Große-Onnebrink, Karolina Gwozdziewicz, Eric G. Haarman, Christine R. Hansen, Claire Hogg, Mathias G. Holgersen, Eitan Kerem, Robert W. Körner, Karsten Kötz, Panayiotis Kouis, Michael R. Loebinger, Natalie Lorent, Jane S. Lucas, Debora Maj, Marcus A. Mall, June K. Marthin, Vendula Martinu, Henryk Mazurek, Hannah M. Mitchison, Tabea Nöthe-Menchen, Ugur Özçelik, Massimo Pifferi, Andrzej Pogorzelski, Felix C. Ringshausen, Jobst F. Roehmel, Sandra Rovira-Amigo, Nisreen Rumman, Anne Schlegtendal, Amelia Shoemark, Synne Sperstad Kennelly, Ben O. Staar, Sivagurunathan Sutharsan, Simon Thomas, Nicola Ullmann, Julian Varghese, Sandra von Hardenberg, Woolf T. Walker, Martin Wetzke, Michal Witt, Panayiotis Yiallouros, Anna Zschocke, Ewa Ziętkiewicz, Kim G. Nielsen, Heymut Omran European Respiratory Journal, 2024
Post-TB bronchiectasis: from pathogenesis to rehabilitation M. A. Martinez-Garcia, W-J. Guan, D. de-la-Rosa, R. Athanazio, G. Oscullo, M-X. Shi, P. Pujal-Montaña, B. N. Endlich, S. Tiberi, R. Centis, G. B. Migliori International Journal of Tuberculosis and Lung Disease, 2023
Factors associated with clinical progression to severe COVID-19 in people with cystic fibrosis: A global observational study Siobhán B Carr, Elliot McClenaghan, Alexander Elbert, Albert Faro, Rebecca Cosgriff, Olzhas Abdrakhmanov, Keith Brownlee, Pierre-Régis Burgel, Catherine A Byrnes, Stephanie Y Cheng, Carla Colombo, Harriet Corvol, Géraldine Daneau, Christopher H Goss, Vincent Gulmans, Hector Gutierrez, Satenik Harutyunyan, Meagan Helmick, Andreas Jung, Nataliya Kashirskaya, Edward McKone, Joel Melo, Peter G Middleton, Pedro Mondejar-Lopez, Isabelle de Monestrol, Lutz Nährlich, Rita Padoan, Megan Parker, M Dolores Pastor-Vivero, Samar Rizvi, Rasa Ruseckaite, Marco Salvatore, Luiz Vicente R F da Silva-Filho, Nick Versmessen, Marco Zampoli, Bruce C Marshall, Anne L Stephenson, Scott C Bell, David Reid, Peter Wark, Eva Van Braeckel, Sophie Gohy, Christiane Knoop, Jessica Pirson, Elke De Wachter, Lieven Dupont, Laurence Hanssens, Vicky Nowé, Monique Lequesne, Rodrigo A Athanazio, Daniela G Meneses, Véronique Boussaud, Graziella Brinchault, Emmanuelle Coirier-Duet, Jean-Christophe Dubus, Dominique Grenet, Sandra de Miranda, Laurence Beaumont, Reem Kanaan, Muriel Lauraens, Clémence Martin, Marie Mittaine, Anne Prévotat, Martine Reynaud-Gaubert, Isabelle Sermet-Gaudelus, Aurelie Tatopoulos, Raphael Chiron, Marie-Laure Dalphin, Michele Gerardin, Laurence Weiss, Nathalie Wizla, Sophie Ramel, Barry Plant, Cedric Gunaratnam, Abaigeal Jackson, Karin de Winter- de Groot, Bart Luijk, Geertjan Wesseling, Elena Kondratyeva, Elena Zhekayte, Elena Amelina, Mariya Mukhina, Olga Simonova, Antonio Alvarez-Fernandez, Amparo Sole-Jover, Isidoro Cortell-Aznar, Rosa Girón-Moreno, Alejandro López-Neyra, Isabel Ramos-Cancelo, Maite Lázaro-Carrasco, Dolores Pastor Vivero, Marta Ruiz de Valbuena, Concepción Prados-Sanchez, Jordi Costa-Colomer, Silvia Gartner, Layla Diab-Caceres, Marita Gilljam, Ulrika Lindberg, Stefanie Diemer, Mark Allenby, Stephen J Bourke, Susan C Charman, Janet Collinson, Owen Dempsey, Sarah Denniston, Maya Desai, Jamie Duckers, Christine Etherington, Elaine Gunn, Alex Higton, Timothy Ho, Jeremy Hull, Andrew Jones, Robert Ian Ketchell, Susan L. Madge, Anirban Maitra, Ghulam Mujtaba, Edward Nash, Dilip Nazareth, Christopher O'Brien, Claire Onyon, Christopher Orchard, Daniel Peckham, Helen Rodgers, Nadia Shafi, Nicholas Simmonds, Kevin Southern, Martin Walshaw, Danie Watson, Joanna L. Whitehouse Journal of Cystic Fibrosis, 2022
Automated Computed Tomography Lung Densitometry in Bronchiectasis Patients Marcio Valente Yamada Sawamura, Rodrigo Abensur Athanazio, Maria Cecília Nieves Teixeira Maiorano de Nucci, Samia Zahi Rached, Alberto Cukier, Rafael Stelmach, Antonildes Nascimento Assuncao-Jr, Marcelo Straus Takahashi, Cesar Higa Nomura Archivos De Bronconeumologia, 2022
Brazilian Guidelines for Nutrition in Cystic Fibrosis Lenycia de Cassya Lopes Neri, Miriam Isabel Souza dos Santos Simon, Valéria Laguna Salomão Ambrósio, Eliana Barbosa, Monique Ferreira Garcia, Juliana Ferreira Mauri, Renata Rodrigues Guirau, Mirella Aparecida Neves, Carolina de Azevedo Pedrosa Cunha, Marcelo Coelho Nogueira, Anna Carolina Di Creddo Alves, Jocemara Gurmini, Maria de Fatima Servidoni, Matias Epifanio, Rodrigo Athanazio Einstein Sao Paulo Brazil, 2022
Essential Features of an Interstitial Lung Disease Multidisciplinary Meeting An International Delphi Survey Alan K. Y. Teoh, Anne E. Holland, Julie Morisset, Kevin R. Flaherty, Athol U. Wells, Simon L. F. Walsh, Ian Glaspole, Wim A. Wuyts, Tamera J. Corte, Huzaifa Adamali, J. Shirine Allam, Sofia Antillon, Katherina M. Antoniou, Rodrigo Athanazio, Sergey Avdeev, Alexander Averyanov, Arata Azuma, Bruno Baldi, Elisabetta Balestro, Rebecca Bascom, Shalini Bastiampillai, Lutz Beckert, Jü¨ergen Behr, Paul Beirne, David Bennett, Raphael Borie, Demosthenes Bouros, Ben Brockway, Kevin Brown, Francisco Javier Callejas González, Diego Castillo, Ronald Chacon Chaves, Daniel Chambers, Sally Chapman, Nazia Chaudhuri, Harold Collard, Vincent Cottin, Bruno Crestani, Jesper Rømhild Davidsen, Devesh J. Dhasmana, Sahajal Dhooria, Juan Ignacio Enghelmayer, Alexandre Todorovic Fabro, Puneet Garcha, Nicole Goh, Alejandro Gomez, Christopher Grainge, Tomohiro Handa, Tristan Huie, Gary Hunninghake, Yoshikazu Inoue, Helen Jo, Kerri Johannson, Rene Jonkers, Eoin Judge, Yasemin Kabasakal, Leticia Kawano Dourado, Gregory Keir, Nasreen Khalil, Yet Hong Khor, Melissa King Biggs, Maria Kokosi, Yasuhiro Kondoh, Vasillis Kouranos, Michael Kreuter, David Lederer, Su Ying Low, Joachim Mü¨ller Quernheim, Toby Maher, Eliane Mancuzo, George Margaritopoulos, Carol Mason, Mariano Mazeini, Nesrin Mogulkoc, Maria Molina, Yuben Moodley, António Morais, Anoop Nambiar, Imre Noth, Hilario Nunes, Takashi Ogura, Oguzhan Okutan, Nina Patel, Carlos Pereira, Wojciech Piotrowski, Venerino Poletti, Silvia Quadrelli, Elzbieta Radzikowska, Pilar Rivera Ortega, Christopher J. Ryerson, Mauricio Salinas, Rafaela Sanchez, Recep Savas, Moises Selman, Adrian Shifren, Maria Raquel Soares, Eman Sobh, Jin Woo Song, Paolo Spagnolo, Martina Sterclova, Irina Strambu, Mary E. Strek, Takafumi Suda, Gabriela Tabaj, Jasna Tekavec Trkanjec, Fatma Tokgoz Akyil, Claudia Toma, Rade Tomic, Hiromi Tomioka, Daniel Traila, Lauren Troy, Sergio Trukillo, Argyrios Tzouvelekis, Carlo Vancheri, Brenda Elena Varela, Francesco Varone, Martina Vasakova, Elizabeth Veitch, Vanesa Vicens Zygmunt, Thomas Wessendorf, Glen Westall, Marlies Wijsenbeek, Margaret L. Wilsher, Jeremy Wrobel, Cesar Yoshito Fukuda, Chris Zappala Annals of the American Thoracic Society, 2022
Symptom variability over the course of the day in patients with stable COPD in Brazil: A real-world observational study Alberto Cukier, Irma de Godoy, Claudia Henrique da Costa, Adalberto Sperb Rubin, Marcelo Gervilla Gregorio, Aldo Agra de Albuquerque Neto, Marina Andrade Lima, Monica Corso Pereira, Suzana Erico Tanni, Rodrigo Abensur Athanazio, Elizabeth Jauhar Cardoso Bessa, ernando Cesar Wehrmeister, Cristina Bassi Lourenco, Ana Maria Baptista Menezes Jornal Brasileiro De Pneumologia, 2020
Severe pulmonary disease in an adult primary ciliary dyskinesia population in Brazil Mary Anne Kowal Olm, Fernando Augusto Lima Marson, Rodrigo Abensur Athanazio, Naomi Kondo Nakagawa, Mariangela Macchione, Niki Tomas Loges, Heymut Omran, Samia Zahi Rached, Carmen Sílvia Bertuzzo, Rafael Stelmach, Paulo Hilário Nascimento Saldiva, José Dirceu Ribeiro, Marcus Herbert Jones, Thais Mauad Scientific Reports, 2019
Prognostic Value of Frequent Exacerbations in Bronchiectasis: The Relationship With Disease Severity Miguel Ángel Martinez-Garcia, Rodrigo Athanazio, Giorgina Gramblicka, Mónica Corso, Fernando Cavalcanti Lundgren, Mara Fernandes de Figueiredo, Francisco Arancibia, Samia Rached, Rosa Girón, Luis Máiz Carro, David de la Rosa Carrillo, Concepción Prados, Casilda Olveira Archivos De Bronconeumologia, 2019
Brazilian consensus on non-cystic fibrosis bronchiectasis Mônica Corso Pereira, Rodrigo Abensur Athanazio, Paulo de Tarso Roth Dalcin, Mara Rúbia Fernandes de Figueiredo, Mauro Gomes, Clarice Guimarães de Freitas, Fernando Ludgren, Ilma Aparecida Paschoal, Samia Zahi Rached, Rosemeri Maurici Jornal Brasileiro De Pneumologia, 2019
Reduced physical activity with bronchiectasis Anderson José, Tamires Machado Ramos, Rejane Agnelo Silva de Castro, Cristiane Santos de Oliveira, Anderson Alves de Camargo, Rodrigo Abensur Athanazio, Samia Zahi Rached, Rafael Stelmach, Simone Dal Corso Respiratory Care, 2018
2018 recommendations for the management of community acquired pneumonia Ricardo de Amorim Corrêa, Andre Nathan Costa, Fernando Lundgren, Lessandra Michelin, Mara Rúbia Figueiredo, Marcelo Holanda, Mauro Gomes, Paulo José Zimermann Teixeira, Ricardo Martins, Rodney Silva, Rodrigo Abensur Athanazio, Rosemeri Maurici da Silva, Mônica Corso Pereira Jornal Brasileiro De Pneumologia, 2018
The annual prognostic ability of FACED and E-FACED scores to predict mortality in patients with bronchiectasis David de la Rosa Carrillo, Rodrigo Athanazio, Rosa Maria Girón Moreno, Luis Máiz Carro, Casilda Olveira, Javier de Gracia, Montserrat Vendrell, Concepción Prados Sánchez, Georgina Gramblicka, Monica Corso Pereira, Fernando Lundgren, Mara Fernandes De Figueiredo, Francisco Arancibia, Samia Rached, Miguel-Angel Martínez-Garcia Erj Open Research, 2018
Diagnostic accuracy of a clinical diagnosis of idiopathic pulmonary fibrosis: An international case-cohort study Simon L.F. Walsh, Toby M. Maher, Martin Kolb, Venerino Poletti, Richard Nusser, Luca Richeldi, Carlo Vancheri, Margaret L. Wilsher, Katerina M. Antoniou, Jüergen Behr, Elisabeth Bendstrup, Kevin Brown, Lucio Calandriello, Tamera J. Corte, Vincent Cottin, Bruno Crestani, Kevin Flaherty, Ian Glaspole, Jan Grutters, Yoshikazu Inoue, Maria Kokosi, Yasuhiro Kondoh, Vasileios Kouranos, Michael Kreuter, Kerri Johannson, Eoin Judge, Brett Ley, George Margaritopoulos, Fernando J. Martinez, Maria Molina-Molina, António Morais, Hilario Nunes, Ganesh Raghu, Christopher J. Ryerson, Moises Selman, Paolo Spagnolo, Hiroyuki Taniguchi, Sara Tomassetti, Dominique Valeyre, Marlies Wijsenbeek, Wim Wuyts, David Hansell, Athol Wells European Respiratory Journal, 2017
Recommendations for the pharmacological treatment of COPD: Questions and answers Frederico Leon Arrabal Fernandes, Alberto Cukier, Aquiles Assunção Camelier, Carlos Cezar Fritscher, Cláudia Henrique da Costa, Eanes Delgado Barros Pereira, Irma Godoy, José Eduardo Delfini Cançado, José Gustavo Romaldini, Jose Miguel Chatkin, José Roberto Jardim, Marcelo Fouad Rabahi, Maria Cecília Nieves Maiorano de Nucci, Maria da Penha Uchoa Sales, Maria Vera Cruz de Oliveira Castellano, Miguel Abidon Aidé, Paulo José Zimermann Teixeira, Renato Maciel, Ricardo de Amorim Corrêa, Roberto Stirbulov, Rodrigo Abensur Athanazio, Rodrigo Russo, Suzana Tanni Minamoto, Fernando Luiz Cavalcanti Lundgren Jornal Brasileiro De Pneumologia, 2017
Latin America validation of FACED score in patients with bronchiectasis: An analysis of six cohorts Rodrigo Athanazio, Mônica Corso Pereira, Georgina Gramblicka, Fernando Cavalcanti-Lundgren, Mara Fernandes de Figueiredo, Francisco Arancibia, Samia Rached, David de la Rosa, Luis Máiz-Carro, Rosa Girón, Casilda Olveira, Concepción Prados, Miguel Angel Martinez-Garcia BMC Pulmonary Medicine, 2017
Predicting high risk of exacerbations in bronchiectasis: The E-FACED score Miguel Angel Martinez-Garcia, Rodrigo A Athanazio, Rosa Maria Girón, Luis Máiz-Carro, David de la Rosa, Casilda Olveira, Javier de Gracia, Montserrat Vendrell, Concepción Prados-Sánchez, Georgina Gramblicka, Mônica Corso Pereira, Fernando Lundgren, Mara Fernandes de Figuereido, Francisco Arancibia, Samia Z Rached International Journal of Copd, 2017
Brazilian guidelines for the diagnosis and treatment of cystic fibrosis Rodrigo Abensur Athanazio, Luiz Vicente Ribeiro Ferreira da Silva Filho, Alberto Andrade Vergara, Antônio Fernando Ribeiro, Carlos Antônio Riedi, Elenara da Fonseca Andrade Procianoy, Fabíola Villac Adde, Francisco José Caldeira Reis, José Dirceu Ribeiro, Lídia Alice Torres, Marcelo Bicalho de Fuccio, Matias Epifanio, Mônica de Cássia Firmida, Neiva Damaceno, Norberto Ludwig-Neto, Paulo José Cauduro Maróstica, Samia Zahi Rached, Suzana Fonseca de Oliveira Melo, Leonardo Araújo Pinto, Luciana Freitas Velloso Monte, Laurinda Yoko Shinzato Higa, Tania Wrobel Folescu, Fernando Augusto de Lima Marson, Isabela Sad, Maria de Fátima Correa Pimenta Servidoni, Paulo Kussek, Salmo Raskin, Adriana Della Zuana, Albin Augustin, Anneliese Hoffmann, Beatriz Barbisan, Bruno Hochhegger, Carlos Emilio Levy, Claudine Sarmento da Veiga, Claudio Ricachinevsky, Concetta Esposito, Dante Escuissato, Diego Brandemburgo, Elisabeth Marques, Evanirso de Aquino, Gilberto Bueno Fischer, Joaquim Carlos Rodrigues, Leticia Machado, Lucia Muramato, Lusmaia Damasceno Camargo Costa, Marcio Donadio, Marcos César Santos de Castro, Maria Angela Ribeiro, Maria Angélica Santana, Mariane Canan, Marina Buarque de Almeida, Murilo Britto, Paulo Roth Tarso Dalcin, Regina Terse Trindade Ramos, Sonia Chiba, Valéria de Carvalho Martins, Claudine Lacerda, Eliana Barbosa, Elizabet Vilar Guimarães, Gabriel Hessel, Jocemara Gurmini, Lenycia Neri, Marcelo Coelho Nogueira, Mônica Chang Wayhs, Miriam Isabel Santos Simon, Arlene Gonçalves dos Santos Fernandes, Claudia de Castro de Silva, Cristiano Túlio Maciel Albuquerque, Edna Lúcia Souza, Fernando Antonio de Abreu e Silva, Paulo de Tarso Dalcin, Renata Maria de Noronha, Ricardo Teixeira, Sandra Helena Machado, Spencer Marcantonio Camargo, Tatiana Rozov, Ticiana da Costa Rodrigues Jornal Brasileiro De Pneumologia, 2017
Systemic corticosteroids as first-line treatment in pulmonary hypertension associated with POEMS syndrome. Jornal Brasileiro De Pneumologia Publicaca Combining Double Acute Accent O Oficial Da Sociedade Brasileira De Pneumologia E Tisilogia, 2009
Soft tissue Rosai-Dorfman disease of the posterior mediastinum Antônio Luiz Penna Costa, Natália Oliveira e Silva, Marina Pamponet Motta, Rodrigo Abensur Athanazio, Daniel Abensur Athanazio, Paulo Roberto Fontes Athanazio Jornal Brasileiro De Pneumologia, 2009
Use of Arizona Sexual Experience Scale (ASEX) for the evaluation of sexual dysfunction in Brazilian oncologic patients Jornal Brasileiro De Psiquiatria, 2005