@57192
Assistant Professor
Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research,Pimpri, Pune
Molecular glues represent a promising class of small molecules that facilitate targeted protein degradation, offering novel therapeutic avenues in cancer and tuberculosis (TB) treatment. These compounds work by promoting the interaction between disease-associated proteins and E3 ubiquitin ligases, leading to selective protein degradation. Research has highlighted the potential of molecular glues to address the limitations of traditional therapies, particularly in resistant cancers and persistent TB infections.The exploration of molecular glues is gaining traction, with ongoing studies aiming to further elucidate their mechanisms and optimize their efficacy for clinical applications in oncology and infectious diseases
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