SONALI LABHADE

@57192

Assistant Professor
Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research,Pimpri, Pune

EDUCATION

PhD Pharmaceutical Sciences, Banasthali Vidyapith, Rajasthan

RESEARCH, TEACHING, or OTHER INTERESTS

Hepatology, Cancer Research, Cell Biology, Chemistry

FUTURE PROJECTS

Molecular glues

Molecular glues represent a promising class of small molecules that facilitate targeted protein degradation, offering novel therapeutic avenues in cancer and tuberculosis (TB) treatment. These compounds work by promoting the interaction between disease-associated proteins and E3 ubiquitin ligases, leading to selective protein degradation. Research has highlighted the potential of molecular glues to address the limitations of traditional therapies, particularly in resistant cancers and persistent TB infections.The exploration of molecular glues is gaining traction, with ongoing studies aiming to further elucidate their mechanisms and optimize their efficacy for clinical applications in oncology and infectious diseases


Applications Invited
Collaborators for research work.
22

Scopus Publications

82

Scholar Citations

5

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • Unveiling the anti-Alzheimer potential of flavonoids: A comprehensive in-silico study
    Smita Jain, Ritesh Bhole, Sonali Labhade
    Vietnam Journal of Chemistry, 2026
    Age‐related dementia is mostly brought on by Alzheimer's disease (AD). As of right now, there are no effective treatments to halt, slow down, or reverse the progression of the illness. Dietary bioactive phytochemicals, particularly flavonoids, have been shown in many studies to impact the pathophysiological mechanisms behind AD. When combined with other medicines, flavonoids are an effective treatment for neurodegenerative disorders. Microtubulin is also a major target in biology for the development of anti‐Alzheimer's drugs linked to the tau protein, which is mostly found in axons and is hyperphosphorylated in AD, perhaps due to the production of pro‐inflammatory cytokines. In this work, 191 flavonoids' in silico ADMET characteristics were analyzed, and then molecular docking was performed using Tubulin protein's VP7 binding site (Id 7jxx). To further examine the stability of the protein‐ligand complex, the best conformation from each flavonoid subcategory with the highest docking score was exposed to 100 ns of molecular dynamics. Using molecular dynamic investigations, several parameters for the four flavonoids were computed, including RMSD, RMSF, rGy, and SASA. There is compelling evidence from this in silico research using molecular docking and molecular dynamics simulation that flavonoids are good anti‐micro‐tubulin drugs for treating AD.
  • Phytochemistry and Pharmacological Activities of Sphagneticola trilobata: A Systematic Review with Perspectives for Drug Discovery
    Sonali Labhade, Suraj Kamadi, Pawan N. Karwa, Ritesh Prakash Bhole, Harshad Sunil Kapare, et al.
    Makara Journal of Science, 2026
    Sphagneticola trilobata (L.) Pruski is a medicinal plant widely used in traditional medicine for its anti-inflammatory, antimicrobial, antioxidant, hepatoprotective, wound healing, and CNS depressant effects. Despite its broad pharmacolo-gical potential, clinical application is limited due to a lack of mechanistic understanding, standardization, and clinical validation. This review aims to provide a comprehensive overview of the phytochemical composition, pharmacological activities, and therapeutic potential of S. trilobata, while highlighting research gaps and suggesting future directions for clinical translation. A systematic review of scientific literature, ethnobotanical sources, and pharmacological studies was conducted, focusing on phytochemical analysis, biological activity, toxicity, and potential applications in evidence-based medicine. Phytochemical studies reveal that S. trilobata contains flavonoids, terpenoids, sesquiterpene lactones, and phe-nolic compounds. Key constituents such as kaurenoic acid, grandiflorenic acid, and wedelolactone are associated with antioxidant, anti-inflammatory, hepatoprotective, antimicrobial, antidiabetic, and anticancer properties. However, there are gaps in understanding its pharmacokinetics, mechanisms of action, and clinical relevance. Although S. trilobata shows strong pharmacological promise, further research is needed to clarify molecular mechanisms, enhance bioavailability, and conduct well-structured clinical trials. These efforts are essential to support its integration into evidence-based and modern medicinal systems.
  • Mapping the global landscape of molecular glues in drug discovery: a bibliometric analysis from 2010 to 2024
    Sonali Labhade, Ritesh Bhole, Pawan Karwa, Harshad Kapare, Subhashini Singh
    Naunyn Schmiedeberg S Archives of Pharmacology, 2026
  • Comparative in vitro Cytotoxicity and Antioxidant Activity of Biologically Derived Nanohydroxyapatite and Commercial Nanohydroxyapatite
    Arati Patil, Nagesh Aloorkar, Anand Kakde, Sonali Labhade, Aniket Garud
    Agricultural Science Digest, 2026
    Background: The poultry industry generates vast amounts of waste, including eggshells, which can be utilized as a source of nanohydroxyapatite (nHAp). This sustainable approach can reduce waste disposal costs, minimize environmental pollution and provide valuable biomaterials for various applications. Methods: Indian Hen eggshells, hybrid Hen eggshells and a commercially available nHAp sample (as a reference) were used in this study. The biologically derived nHAp samples were synthesized via a precipitation method and the antioxidant activity and cytotoxicity of the nHAp samples were evaluated via the DPPH (1,1-Diphenyl-2-picrylhydrazyl) assay and MTT (Cell sensitivity) assay, respectively. Result: The results of the DPPH assay revealed that 3.125 μg/mL ascorbic acid was equivalent to 250 μg/mL Indian Hen eggshell-derived nHAp (IE1), whereas 1.56 μg/mL ascorbic acid was equivalent to 50 μg/mL hybrid Hen eggshell-derived nHAp (HE1). The reference sample showed that 0.78 μg/mL ascorbic acid was equivalent to 1 μg/mL ascorbic acid. The MTT assay revealed that all three nHAp samples were noncytotoxic and presented varying IC50 values (IE1: 1797 μg/mL, HE1: 1348 μg/mL, reference: 1972 μg/mL), indicating potential suitability for biomedical applications.
  • Next-generation cancer immunotherapy: the promise of CAR T-Cell therapy
    Harshad S. Kapare, Rutuja Jadhav, Pawan N. Karwa, Ritesh P. Bhole, Sonali Labhade
    Immunotherapy, 2026
    Chimeric antigen receptor (CAR) T-cell treatment has developed among major substantial improvements for modern cancer treatment, providing sustained responses in patients with otherwise resistant blood cancers. This method comprises of patients reprogramming or donor's T lymphocytes to interpret tumor associated antigens self-sufficiently of major histocompatibility multifaceted presentation, thereby circumventing a key limitation of natural immune surveillance. The approval of CD19- and BCMA-targeted therapies demonstrated remarkable clinical impact and validated the approach. Over successive generations, CAR constructs have been refined with additional costimulatory elements, cytokine support, and multifunctional signaling domains, improving both their persistence and therapeutic activity. Despite such progress, important challenges remain, including risks of relapse, toxicity including neurotoxicity and cytokine release syndrome with limited efficacy in solid tumors. Current research is focused on strategies, such as armored CARs, gene editing, and combination therapies to expand clinical benefit. A comprehensive literature search was conducted using PubMed, Scopus, and Web of Science databases, covering publications from 2000 to 2026 till date. Relevant peer-reviewed articles were selected based on their relevance to CAR T-cell therapy, including preclinical and clinical studies. Detailed search strategy, inclusion criteria, and screening methods are described in the main manuscript. This review explores the evolution, applications, and future outlook of CAR T-cell rehabilitation.
  • Next-Generation Therapies for Genetic Diseases: The Synergy of CRISPR and Gene Therapy
    Pawan Karwa, Atharva Kharul, Vaibhav Parekar, Sonali Labhade, Nikhil Sakle, Ritesh Bhole, Harshad Kapare
    Biochemical Genetics, 2026
  • Phyto-Assisted Synthesis and Investigation of Zinc Oxide Nanoparticles for Their Anti-Aging, Sun Protection and Antibacterial Activity
    Harshad S. Kapare, Mayuri Bhosale, Pawan Karwa, Deepak Kulkarni, Ritesh Bhole, Sonali Labhade
    Cosmetics, 2025
    Objective: This study aimed to develop eco-friendly zinc oxide nanoparticles (ZnO NPs) using Punica granatum (pomegranate) peel extract and to evaluate their antioxidant, antimicrobial, and photoprotective potential. Method: ZnO NPs were synthesized via a green chemistry route employing polyphenol- and flavonoid-rich peel extract as reducing and stabilizing agents. The nanoparticles were characterized using FTIR, SEM, XRD, DSC, DLS, and UV–Vis spectroscopy. Biological activities were assessed through in vitro assays including antioxidant (DPPH), anti-collagenase, anti-elastase, anti-tyrosinase, antimicrobial activity, and SPF determination. In vivo photoprotective efficacy was further evaluated in UVB-irradiated rat models, with histological analysis to confirm structural skin changes. Results: The optimized ZnO NPs exhibited an average particle size of ~194 nm with a zeta potential of −18.2 mV, indicating good stability. They demonstrated notable antioxidant activity (DPPH IC50 = 52.91 µg/mL), substantial tyrosinase inhibition (72% at 200 µg/mL), and antibacterial activity with inhibition zones up to 19 mm against S. aureus and 17 mm against E. coli. The nanoparticles also showed excellent UV absorption, with an SPF value of 29.8, exceeding the FDA threshold for effective sun protection. In vivo, topical application of ZnO NPs in UVB-exposed rats led to a 69% reduction in epidermal thickness and preservation of collagen fibers compared with UV controls. Conclusions: These findings confirm that P. granatum peel extract–mediated ZnO NPs possess significant antioxidant, antimicrobial, and photoprotective activities.
  • Daidzein targets PI3K-Akt signaling and oxidative stress in glioblastoma: An Integrated pharmacological and in vitro study
    Chinchu Praisthy L J, Ravi Kushwah, Sachin Dubey, Sonali Labhade, Pawan Karwa, Smita Jain
    Brain Research, 2025
  • MED12 dysregulation: insights into cancer and therapeutic resistance
    Ritesh Bhole, Jagruti Shinkar, Sonali Labhade, Pawan Karwa, Harshad Kapare
    Naunyn Schmiedeberg S Archives of Pharmacology, 2025
  • REVOLUTIONIZING HEALTHCARE: UNVEILING THE POWER OF REGENERATIVE MEDICINE AND TISSUE ENGINEERING
    Ritesh Bhole, Harshad Kapare, Pawan Karwa, Sonali Labhade
    Bulletin of Pharmaceutical Sciences Assiut, 2025
    This comprehensive review explores the integration of stem cell therapies and tissue engineering, driving advancements as a new regenerative medicine approach. It discusses diverse applications across various tissues, including bone, cartilage, heart, skin, neural, liver, ocular, muscle, and renal tissues. Successful outcomes, such as bone fracture management, cardiac tissue regeneration, and spinal cord injury repair, are highlighted through compelling case studies. The review emphasizes challenges like immune rejection risks and regulatory complexities in translating these techniques to clinical practice. It also underscores the use of biomolecules, growth factors, and controlled release strategies to guide tissue maturation. Collaboration among researchers, clinicians, and regulatory agencies is crucial, and personalized medicine offers promise for individualized treatment. Emerging trends, like organoids and organ-on-a-chip technologies, are reshaping the field, potentially reducing reliance on donor organs. Regulatory considerations, interdisciplinary collaboration, and innovative technologies converge to unlock regenerative medicine's transformative potential for biomedical research and patient care.
  • Systematic Review of Medication Errors: An Overview of the Literature by Clinical Pharmacists
    Karishma Rathi, Sonali Labhade, Nayana S. Jayachandran, Tanvi Sarode
    International Journal of Pharmaceutical Sciences and Nanotechnology, 2025
  • A Closer Look at Guillain-Barré Syndrome: The Need for Literature Research & Data Collection
    Atharva Kharul, Umesh Bargal, Pawan Karwa, Ritesh Bhole, Sonali Labhade
    International Journal of Pharmaceutical Sciences and Nanotechnology, 2025
  • Conquering PROTAC molecular design and drugability
    Ritesh P. Bhole, Sonali Labhade, Shilendra S. Gurav
    Bioanalysis, 2025
  • Punica granatum L. (Punicaceae): An Insight into Phytochemistry and Pharmacology
    Sonali Labhade, Pranali Jadhav, Ritesh Bhole, Sohan Chitlange
    Current Traditional Medicine, 2025
  • Exploring SGLT2 Inhibitors' Activity in Breast Cancer: An Overview
    Ritesh P. Bhole, Gayatri S. Maldhure, Harshad S. Kapare, Sonali D. Labhade, Shailendra S. Gurav
    Current Topics in Medicinal Chemistry, 2025
  • Advances in targeting p38 MAPK for cancer therapy: insights from molecular pharmacology and medicinal chemistry
    Ritesh P. Bhole, Nishigandha kadam, Pawan N. Karwa, Sonali D. Labhade, Harshad S. Kapare, Shailendra Gurav
    Molecular Diversity, 2025
  • S-adenosylmethionine supplementation to alleviate depression symptoms in patients with suboptimal response to standard antidepressive therapy: a perspective
    Sonali Labhade, Ritesh Bhole, Smita Jain
    East Asian Archives of Psychiatry, 2024
  • CyPD inhibition for Alzheimer's: In silico screening of phytochemicals from Asian medicinal plants
    Dr Smita Jain, Dr Ritesh Bhole, Dr Sonali D Labhade
    Indian Journal of Chemistry Ijc, 2024
  • Development and analysis of a herbal bath bomb for its antifungal properties
    Sonali D Labhade, Harshad S Kapare, Juilee S Jagtap, Sohan S Chitlange, Karishma M Rathi
    Ip Indian Journal of Clinical and Experimental Dermatology, 2024
  • Decalepis hamiltonii root fraction alleviates CCl4 hepatotoxicity in a rat model
    Sonali Labhade, Smita Jain, Sohan Chitlange, Sarvesh Paliwal, Swapnil Sharma
    Journal of Ayurveda and Integrative Medicine, 2023
  • An Overview of Some Plant Based Products With Hepatoprotective Activity(A review)
    Sonali Dnyaneshwar Labhade, Swapnil Sharma, Sarvesh Paliwal, Shivani Desai
    Iraqi Journal of Pharmaceutical Sciences, 2021
  • Solid- lipid nanoparticles: A newer approach for formulation and optmization of HMG-CoA reductase inhibitors
    Research Journal of Pharmaceutical Biological and Chemical Sciences, 2013

RECENT SCHOLAR PUBLICATIONS

  • Next-generation cancer immunotherapy: the promise of CAR T-Cell therapy
    HS Kapare, R Jadhav, PN Karwa, RP Bhole, S Labhade
    Immunotherapy, 1-22 , 2026
    2026
  • Next-Generation Therapies for Genetic Diseases: The Synergy of CRISPR and Gene Therapy
    P Karwa, A Kharul, V Parekar, S Labhade, N Sakle, R Bhole, H Kapare
    Biochemical Genetics, 1-79 , 2026
    2026
  • Phytochemistry and Pharmacological Activities of Sphagneticola trilobata: A Systematic Review with Perspectives for Drug Discovery
    SD Labhade, S Kamadi, PN Karwa, RP Bhole, HS Kapare, SS Chitlange
    Makara Journal of Science 30 (1), 12 , 2026
    2026
  • Investigation of novel hybrid analogues for their antitubercular pharmacological potential
    RP Bhole, PM Karche, PN Karwa, SD Labhade, HS Kapare
    Future Journal of Pharmaceutical Sciences 11 (1), 151 , 2025
    2025
  • Phyto-Assisted Synthesis and Investigation of Zinc Oxide Nanoparticles for Their Anti-Aging, Sun Protection and Antibacterial Activity
    HS Kapare, M Bhosale, P Karwa, D Kulkarni, R Bhole, S Labhade
    Cosmetics 12 (6), 238 , 2025
    2025
    Citations: 4
  • Exploring SGLT2 Inhibitors' Activity in Breast Cancer: An Overview
    RP Bhole, GS Maldhure, H Kapare, SD Labhade, SS Gurav
    Current Topics in Medicinal Chemistry 25 (24), 2864-2887 , 2025
    2025
    Citations: 2
  • Cutting-Edge Approaches in Vitiligo Therapy: A New Era of Treatment Options
    P Karwa, U Bargal, S Dhende, S Labhade, R Bhole, H Kapare, N Sakle
    Bulletin of Pharmaceutical Sciences Assiut University , 2025
    2025
  • MED12 dysregulation: insights into cancer and therapeutic resistance
    R Bhole, J Shinkar, S Labhade, P Karwa, H Kapare
    Naunyn-Schmiedeberg's Archives of Pharmacology 398 (8), 10049-10069 , 2025
    2025
    Citations: 5
  • Advances in targeting p38 MAPK for cancer therapy: insights from molecular pharmacology and medicinal chemistry
    RP Bhole, N Kadam, PN Karwa, SD Labhade, HS Kapare, S Gurav
    Molecular Diversity, 1-29 , 2025
    2025
    Citations: 5
  • Daidzein targets PI3K-Akt signaling and oxidative stress in glioblastoma: An Integrated pharmacological and in vitro study
    LJC Praisthy, R Kushwah, S Dubey, S Labhade, P Karwa, S Jain
    Brain Research, 149840 , 2025
    2025
    Citations: 9
  • Systematic Review of Medication Errors: An Overview of the Literature by Clinical Pharmacists
    K Rathi, S Labhade, NS Jayachandran, T Sarode
    International Journal of Pharmaceutical Sciences and Nanotechnology (IJPSN … , 2025
    2025
  • A Closer Look at Guillain-Barré Syndrome: The Need for Literature Research & Data Collection
    A Kharul, U Bargal, P Karwa, R Bhole, S Labhade
    International Journal of Pharmaceutical Sciences and Nanotechnology (IJPSN … , 2025
    2025
  • Conquering PROTAC molecular design and drugability
    RP Bhole, S Labhade, SS Gurav
    Bioanalysis 17 (7), 455-470 , 2025
    2025
    Citations: 10
  • Mapping the global landscape of molecular glues in drug discovery: A bibliometric analysis from 2010 to 2024
    S Labhade, R Bhole, P Karwa, H Kapare, S Singh
    Naunyn-Schmiedeberg's Archives of Pharmacology 399 (3), 4321-4339 , 2025
    2025
    Citations: 1
  • Unveiling the anti‐Alzheimer potential of flavonoids: A comprehensive in‐silico study
    S Jain, R Bhole, S Labhade
    Vietnam Journal of Chemistry 64 (2), 299-312 , 2025
    2025
  • Comparative Invitro Cytotoxicity and Antioxidant Activity of Biologically Derived Nanohydroxyapatite and Commercial Nanohydroxyapatite
    AG Arati Patil, Nagesh Aloorkar, Anand Kakde, Sonali Labhade
    Agricultural Science Digest 45 (3), 1-10 , 2025
    2025
  • Revolutionizing healthcare: Unveiling the power of regenerative medicine and tissue engineering
    R Bhole, H Kapare, P Karwa, S Labhade
    Bulletin of Pharmaceutical Sciences Assiut University , 2025
    2025
    Citations: 2
  • Punica granatum L. (Punicaceae): An Insight into Phytochemistry and Pharmacology
    S Labhade, P Jadhav, R Bhole, S Chitlange
    Current Traditional Medicine 11 (1), e311023222941 , 2025
    2025
    Citations: 1
  • Punica granatum: Exploring Phytochemistry and Pharmacology
    SC Sonali Labhade, Pranali Jadhav, Ritesh Bhole
    Current Traditional Medicine 11 (1) , 2025
    2025
  • Development and analysis of a herbal bath bomb for its antifungal properties
    KMR Sonali D Labhade,Harshad S Kapare, Juilee S Jagtap, Sohan S Chitlange
    IP Indian Journal of Clinical and Experimental Dermatology 10 (1), 28-31 , 2024
    2024

MOST CITED SCHOLAR PUBLICATIONS

  • Development and validation of RP-HPLC method for simultaneous determination of diclofenac sodium and tizanidine hydrochloride in bulk and tablet formulation
    SD Labhade, SR Chaudhari, RB Saudagar
    J. Anal. Pharm. Res 7 (2), 244-247 , 2018
    2018
    Citations: 20
  • Conquering PROTAC molecular design and drugability
    RP Bhole, S Labhade, SS Gurav
    Bioanalysis 17 (7), 455-470 , 2025
    2025
    Citations: 10
  • Daidzein targets PI3K-Akt signaling and oxidative stress in glioblastoma: An Integrated pharmacological and in vitro study
    LJC Praisthy, R Kushwah, S Dubey, S Labhade, P Karwa, S Jain
    Brain Research, 149840 , 2025
    2025
    Citations: 9
  • MED12 dysregulation: insights into cancer and therapeutic resistance
    R Bhole, J Shinkar, S Labhade, P Karwa, H Kapare
    Naunyn-Schmiedeberg's Archives of Pharmacology 398 (8), 10049-10069 , 2025
    2025
    Citations: 5
  • Advances in targeting p38 MAPK for cancer therapy: insights from molecular pharmacology and medicinal chemistry
    RP Bhole, N Kadam, PN Karwa, SD Labhade, HS Kapare, S Gurav
    Molecular Diversity, 1-29 , 2025
    2025
    Citations: 5
  • Phyto-Assisted Synthesis and Investigation of Zinc Oxide Nanoparticles for Their Anti-Aging, Sun Protection and Antibacterial Activity
    HS Kapare, M Bhosale, P Karwa, D Kulkarni, R Bhole, S Labhade
    Cosmetics 12 (6), 238 , 2025
    2025
    Citations: 4
  • LC/MS characterization of secondary metabolites of Sphagneticola trilobata J. F Pruski Leaves.
    S Labhade, S Jain, S Chitlange, S Sharma
    Journal of Pharmaceutical Negative Results 14 (3) , 2023
    2023
    Citations: 4
  • A solid lipid nanoparticle: As novel drug delivery: An overview
    S Labhade, R Saudagar
    WJPPS 4 (4), 462-89 , 2015
    2015
    Citations: 4
  • CyPD Inhibition for Alzheimer's: In-Silico Screening of Phytochemicals from Asian Medicinal Plants: CyPD Inhibition for Alzheimer's: In-Silico Screening of Phytochemicals from …
    S Jain, R Bhole, SD Labhade
    Indian Journal of Chemistry (IJC) 63 (5), 473-484 , 2024
    2024
    Citations: 3
  • Telemedicine: present, future and applications
    HS Kapare, KM Rathi, SD Labhade
    Telemedicine: The Computer Transformation of Healthcare, 311-320 , 2022
    2022
    Citations: 3
  • An Overview of Some Plant Based Products With Hepatoprotective Activity
    SD Labhade, S Sharma, S Paliwal, S Desai
    Iraqi Journal of Pharmaceutical Sciences 30 (2), 1-15 , 2021
    2021
    Citations: 3
  • Development and evaluation of bio-transformed fruit face pack
    SD Labhade, K Tomi
    Research Journal of Topical and Cosmetic Sciences 6 (1), 44 , 2015
    2015
    Citations: 3
  • Exploring SGLT2 Inhibitors' Activity in Breast Cancer: An Overview
    RP Bhole, GS Maldhure, H Kapare, SD Labhade, SS Gurav
    Current Topics in Medicinal Chemistry 25 (24), 2864-2887 , 2025
    2025
    Citations: 2
  • Revolutionizing healthcare: Unveiling the power of regenerative medicine and tissue engineering
    R Bhole, H Kapare, P Karwa, S Labhade
    Bulletin of Pharmaceutical Sciences Assiut University , 2025
    2025
    Citations: 2
  • Solid-Lipid Nanoparticles: A Newer Approach For Formulation And Optimization Of HMG-CoA Reductase Inhibitors”
    SD Labhade, PS Gide, RB Saudagar
    Research Journal of Pharmaceutical, Biological and Chemical Sciences 4 (3 … , 2013
    2013
    Citations: 2
  • Mapping the global landscape of molecular glues in drug discovery: A bibliometric analysis from 2010 to 2024
    S Labhade, R Bhole, P Karwa, H Kapare, S Singh
    Naunyn-Schmiedeberg's Archives of Pharmacology 399 (3), 4321-4339 , 2025
    2025
    Citations: 1
  • Punica granatum L. (Punicaceae): An Insight into Phytochemistry and Pharmacology
    S Labhade, P Jadhav, R Bhole, S Chitlange
    Current Traditional Medicine 11 (1), e311023222941 , 2025
    2025
    Citations: 1
  • Decalepis hamiltonii root fraction alleviates CCl4 hepatotoxicity in a rat model
    S Labhade, S Jain, S Chitlange, S Paliwal, S Sharma
    Journal of Ayurveda and Integrative Medicine 14 (6), 100818 , 2023
    2023
    Citations: 1
  • Next-generation cancer immunotherapy: the promise of CAR T-Cell therapy
    HS Kapare, R Jadhav, PN Karwa, RP Bhole, S Labhade
    Immunotherapy, 1-22 , 2026
    2026
  • Next-Generation Therapies for Genetic Diseases: The Synergy of CRISPR and Gene Therapy
    P Karwa, A Kharul, V Parekar, S Labhade, N Sakle, R Bhole, H Kapare
    Biochemical Genetics, 1-79 , 2026
    2026

Publications

Research Paper Entitled “Spectrophotmetric Determination and Validation of Glimeperide Concentration in Bulk and Dosage Form” In American Journal of Pharmatech Research, 2015; 5(3):208-13. (Impact Factor: 0.9832).
Research Paper entitled “Formulation and Evaluation of Carvedilol loaded Solid Lipid Nanoparticles” In International Journal of Scientific Progress &Research (IJSPR), 2015; 13(2): 74-78. (Impact factor:1.815)
Research Paper entitled “Development and Validation of RP-HPLC Method for Simultaneous Determination of Diclofenac Sodium and Tizanidine Hydrochloride in bulk and Tablet Formulation” In International Journal of Scientific Research in Science and Technology (IJSRST) 2018; 4(2) Page: 1413-1417.
Review article entitled “Biopolymer Conjugated Protein Based Hydrogel Scaffolds for Tissue Engineering Application” in International Journal of Pharmacy and Pharmaceutical Research, Jan 2020, 17(2) Page: 286-316.
10. N-butanol fraction of Decalepis hamiltonii root shows potential to possess antiproliferative activity and combat oxidative damage in European Chemical Bulletin 2023; 12(5) 3896-3923.
11. Development And Validation of Rp-Hplc Method For Assay of Fluticasone Furoate From Nasal Spray Formulation in European Chemical Bulletin 2023; (Special Issue 1) 2543-2555.
12. S. D. Labhade, S. Jain, S. S. Chitlange, S. Paliwal, S. Sharma, “Decalepis hamiltonii root fraction alleviates CCl4 hepatotoxicity in a rat model via inhibiting oxidative stress, proinflammatory cytokin

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

Patent on Synthesis of PROTAC derivatives as anticancer agents
Publication date: 09/08/2024