Incidental hepatic steatosis identified on ultrasound in patients undergoing cholecystectomy: high prevalence and insufficient investigative and clinical management Heloísa Mello TRAPP, Paulo André Bispo MACHADO-JÚNIOR, Silvania Klug PIMENTEL Arquivos De Gastroenterologia, 2025 Background: Steatotic liver disease (SLD) affects about 1 billion people globally, making its proper management essential to prevent progression to more severe stages. Objective: The aim of this study was to evaluate medical management concerning hepatic steatosis incidentally identified by ultrasound in patients undergoing elective cholecystectomy. Methods: This observational, cross-sectional, and retrospective study included patients aged 18 years or older who underwent elective cholecystectomy at Hospital do Trabalhador, in Curitiba/PR, between 2018 and 2022. Patients with external ultrasound reports or incomplete data in their medical records were excluded. Medical records, laboratory tests, and ultrasound reports were analyzed to evaluate the prevalence of steatosis in these patients. Results: The study sample consisted of 355 patients, and 103 (29.01%) of them presented steatosis on ultrasound. Older age (P=0.0022), male sex (P=0.03009), higher body mass index (P<0.001), obesity (P<0.001), hypertension (P<0.001), dyslipidemia (P=0.0072), and elevated levels of oxaloacetic and pyruvic aminotransferases (P=0.02112) were associated with the presence of this finding. No action was taken regarding the presence of steatosis in 60.19% of patients. Approximately 39.81% had the finding recorded in their medical records, 6.80% received lifestyle change counseling, and 4.85% were investigated for the stage of steatosis. Conclusion: A significant prevalence of hepatic steatosis was incidentally identified in the ultrasound of patients undergoing cholecystectomy. However, the approach to this finding was insufficient, highlighting the need for substantial improvements on its management and investigation.
Emergency room readmission, an avoidable problem? Analysis and stratification of readmissions in a trauma reference center EDUARDO TAKEMURA ADANIA, GILSON SOARES DE FARIA JUNIOR, NICOLE RAMPANI FRANZONI, SILVANIA KLUG PIMENTEL Revista do Colegio Brasileiro De Cirurgioes, 2024 Introduction: Hospital readmission is a common way to assess the quality of care provided in an emergency service. In this context, the aim of this study is to quantify and stratify readmissions in a trauma reference emergency service. Methods: A retrospective longitudinal study was conducted with patients readmitted, twice or more, in the emergency service within a maximum period of 30 days from the initial admission - hospitalized or not. Clinical and demographic data were obtained from electronic medical records. Results: The readmission rate for the service was 4.11% for all readmissions and 2.23% for avoidable readmissions. Within this group, 61.19% were likely avoidable, 19.47% possibly avoidable, and 19.34% eventually avoidable. Regarding time, 48.16% occurred within one week of the initial readmission. Furthermore, no statistically significant association was found in the analysis of biological sex, occupational accident, and comorbidities. A statistically significant association was found in the analysis of age and ambulance transport (OR 1.37; 95% CI 1.17-1.59). Conclusion: The study highlighted that there are still readmissions in the emergency department that could be avoided. A significant relationship was observed between readmissions and patient ages, and ambulance transport.
Comparison of tomographic reports by radiologists and non-radiologists in trauma and interferences in management in a trauma reference center GABRIEL MONDIN NOGUEIRA, LEONARDO KRIEGER RAFAEL, GABRIEL SEBBEN REICHARDT, MATEUS DALL’AGNOL, SILVANIA KLUG PIMENTEL Revista do Colegio Brasileiro De Cirurgioes, 2023 Objective: diagnostic errors during the interpretation of an imaging test by the physician can lead to increased mortality and length of hospital stay for patients. The rate of divergence in the report given by a radiologist and an Emergency Physicians (EP) can reach over 20%. The objective of this study was to compare the unofficial tomographic reports issued by EP with the official reports issued by radiologists. Methods: a cross-sectional study, in which interpretations of the exams (documented in the medical records by the EP) of all patients undergoing computed tomography (CT) of the chest, abdomen or pelvis performed in the emergency room, at an interval of 8 months, were evaluated. These data were compared with the official reports of the radiologist (gold standard). Results: 508 patients were included. The divergence between EP and the radiologist occurred in 27% of the cases. The most common type of divergence was the one not described by the EP, but described by the radiologist. The chance of having divergence in a case of multiple trauma is 4.93 times greater in relation to the case of only blunt trauma in one segment. A statistically relevant difference was also found in the length of stay of patients who had different interpretations of the CT scans. Conclusion: the study found a relatively high divergence rate between the EP report and the official radiologist report. However, less than 4% of these were considered to be clinically relevant, indicating the ability of the EP to interpret it satisfactorily.
RISK FACTORS FOR SURGICAL WOUND INFECTION AFTER ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY Gustavo de Oliveira GAMO, Gabriel Sebben REICHARDT, Camila Roginski GUETTER, Silvania Klug PIMENTEL Arquivos Brasileiros De Cirurgia Digestiva Abcd Brazilian Archives of Digestive Surgery, 2022 BACKGROUND: One of the ways to avoid infection after surgical procedures is through antibiotic prophylaxis. This occurs in cholecystectomies with certain risk factors for infection. However, some guidelines suggest the use of antibiotic prophylaxis for all cholecystectomies, although current evidence does not indicate any advantage of this practice in the absence of risk factors. AIMS: This study aims to evaluate the incidence of wound infection after elective laparoscopic cholecystectomies and the use of antibiotic prophylaxis in these procedures. METHODS: This is a retrospective study of 439 patients with chronic cholecystitis and cholelithiasis, accounting for different risk factors for wound infection. RESULTS: There were seven cases of wound infection (1.59%). No antibiotic prophylaxis regimen significantly altered infection rates. There was a statistically significant correlation between wound infection and male patients (p=0.013). No other analyzed risk factor showed a statistical correlation with wound infection. CONCLUSIONS: The nonuse of antibiotic prophylaxis and other analyzed factors did not present a significant correlation for the increase in the occurrence of wound infection. Studies with a larger sample and a control group without antibiotic prophylaxis are necessary.
RISK FACTORS FOR SURGICAL WOUND INFECTION AFTER ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY Gustavo de Oliveira GAMO, Gabriel Sebben REICHARDT, Camila Roginski GUETTER, Silvania Klug PIMENTEL Arquivos Brasileiros De Cirurgia Digestiva, 2022 BACKGROUND: One of the ways to avoid infection after surgical procedures is through antibiotic prophylaxis. This occurs in cholecystectomies with certain risk factors for infection. However, some guidelines suggest the use of antibiotic prophylaxis for all cholecystectomies, although current evidence does not indicate any advantage of this practice in the absence of risk factors. AIM: This study aimed to evaluate the incidence of wound infection after elective laparoscopic cholecystectomies and the use of antibiotic prophylaxis in these procedures. METHODS: This is a retrospective study of 439 patients with chronic cholecystitis and cholelithiasis, accounting for different risk factors for wound infection. RESULTS: There were 7 (1.59%) cases of wound infection. No antibiotic prophylaxis regimen significantly altered infection rates. There was a statistically significant correlation between wound infection and male patients (p=0.013). No other analyzed risk factor showed a statistical correlation with wound infection. CONCLUSIONS: The non-use of antibiotic prophylaxis and other analyzed factors did not present a significant correlation for the increase in the occurrence of wound infection. Studies with a larger sample and a control group without antibiotic prophylaxis are necessary.
CT scan in the evaluation of pediatric abdominal trauma ISABELLA PERIN, CAMILA ROGINSKI GUETTER, LÚCIO EDUARDO KLÜPPEL, CAMILA GIRARDI FACHIN, SILVANIA KLUG PIMENTEL Revista do Colegio Brasileiro De Cirurgioes, 2022 Objective: to assess the need of computed tomography (CT) for the definition of management in pediatric abdominal trauma. Methods: observational retrospective study with patients under 18 years old victims of blunt or penetrating abdominal trauma that underwent CT of the abdomen and pelvis at admission. We evaluated CT scan findings, indications and management. We calculated the sensitivity, specificity, positive predictive value and negative predictive value of clinical variables and energy of trauma for findings on CT. Results: among the 236 patients included in our study, 72% (n=170) did not present abnormal findings on CT. It was performed surgical treatment in 15% (n=10), conservative treatment in 54,5% (n=36) and 27% (n=18) did not receive treatment for abdominal injuries. In the assessment of CT indications, 28,8% (n=68) presented no justifications. In this group, 91% (n=62) did not show any abnormal findings. Among the six patients with positive findings, half were selected for conservative treatment, while the rest did not need any treatment for abdominal injuries. The presence of abdominal pain, hemodynamic alterations and high energy blunt trauma had low positive predictive values when isolated, whereas the negative predictive values were higher. Conclusion: although CT is necessary in some instances, there is a possible high number of exams that did not make any difference in the management of the pediatric population.
Lumbar and para-iliac hernias: an alternative technique MARIA PESSOLE BIONDO SIMÕES, ALEXANDRE CONTIN MANSUR, SILVANIA KLUG PIMENTEL Revista do Colegio Brasileiro De Cirurgioes, 2021 Lumbar and para-iliac hernias are rare and occur after removal of an iliac bone graft, nephrectomies, retroperitoneal aortic surgery, or after blunt trauma to the abdomen. The incidence of hernia after the removal of these grafts ranges from 0.5 to 10%. These hernias are a problem that surgeons will face, since bone grafts from the iliac crest are being used more routinely. The goal of this article was to report the technique to correct these complex hernias, using the technique of fixing the propylene mesh to the iliac bone and the result of this approach. In the period of 5 years, 165 patients were treated at the complex hernia service, 10 (6%) with hernia in the supra-iliac and lumbar region, managed with the technique of fixing the mesh to the iliac bone with correction of the failure. During the mean follow-up of 33 months (minimum of 2 and maximum of 48 months), there was no recurrence of the hernias.
Ct scanning in blunt chest trauma: Validation of decision instruments GABRIEL SEBBEN REICHARDT, GABRIEL MONDIN NOGUEIRA, LEONARDO KRIEGER RAFAEL, PAULO ROBERTO SOLTOSKI, SILVANIA KLUG PIMENTEL Revista do Colegio Brasileiro De Cirurgioes, 2020 Objective: to perform an external validation of two clinical decision instruments (DIs) - Chest CT-All and Chest CT-Major - in a cohort of patients with blunt chest trauma undergoing chest CT scanning at a trauma referral center, and determine if these DIs are safe options for selective ordering of chest CT scans in patients with blunt chest trauma admitted to emergency units. Methods: cross-sectional study of patients with blunt chest trauma undergoing chest CT scanning over a period of 11 months. Chest CT reports were cross-checked with the patients’ electronic medical record data. The sensitivity and specificity of both instruments were calculated. Results: the study included 764 patients. The Chest CT-All DI showed 100% sensitivity for all injuries and specificity values of 33.6% for injuries of major clinical significance and 40.4% for any lesion. The Chest CT-Major DI had sensitivity of 100% for injuries of major clinical significance, which decreased to 98.6% for any lesions, and specificity values of 37.4% for injuries of major clinical significance and 44.6% for all lesions. Conclusion: both clinical DIs validated in this study showed adequate sensitivity to detect chest injuries on CT and can be safely used to forego chest CT evaluation in patients without any of the criteria that define each DI. Had the Chest CT-All and Chest CT-Major DIs been applied in this cohort, the number of CT scans performed would have decreased by 23.1% and 24.6%, respectively, resulting in cost reduction and avoiding unnecessary radiation exposure.
Computerized axial tomography in patients with severe abdominal trauma: Is it a justifiable risk? Silvania Klug Pimentel, Paula Adamo de Almeida, Gustavo Pás Shimizu, Fábio Henrique de Carvalho Revista do Colegio Brasileiro De Cirurgioes, 2019 RESUMO Objetivo: avaliar a evolução de pacientes vítimas de trauma abdominal grave, nos quais o protocolo de transfusão maciça foi acionado, e que foram submetidos à Tomografia Axial Computadorizada (TAC) no Pronto Socorro (PS), com o intuito de verificar o prognóstico do paciente e a eficiência diagnóstica da TAC nesse cenário. Métodos: estudo retrospectivo, longitudinal e observacional, feito em centro de referência para trauma. Foram selecionados 60 pacientes vítimas de trauma abdominal grave que ativaram o protocolo de transfusão maciça, divididos em dois grupos: os submetidos à TAC no PS e os que não foram. Verificou-se a acurácia da TAC, comparou-se o número de óbitos nos dois grupos, o tempo de internamento e os hemocomponentes transfundidos. Resultados: dos 60 pacientes, 66,67% receberam concentrados de hemácias ainda no PS; 33,3% foram submetidos à TAC na admissão, pela melhora hemodinâmica, e 66,7% não realizaram o exame na entrada. O percentual de óbitos foi de 35% em ambos os grupos. A diferença entre as médias do tempo de internamento entre os grupos não foi estatisticamente significativa, assim como a média da quantidade de concentrado de hemácias transfundido. No grupo que fez TAC, 45% não necessitaram de laparotomia exploratória. Conclusão: a TAC pôde ser realizada de maneira rápida em pacientes com instabilidade hemodinâmica na chegada ao PS, não influenciou significativamente a mortalidade e poupou alguns doentes de uma laparotomia exploratória desnecessária.
Liver and Bile Duct Trauma Ana Gabriela Clemente, Silvania Klug Pimentel, Mariana F. Jucá Moscardi, Jonathan Meizoso, Rishi Rattan Trauma Golden Hour A Practical Guide, 2019
Penetrating Neck Trauma Mariana F. Jucá Moscardi, Silvania Klug Pimentel, Fernanda Cristina Silva, Jean Raitz Novais, Antonio Marttos Trauma Golden Hour A Practical Guide, 2019
Donor quality of life after living donor liver transplantation Júlio Cezar Uili Coelho, Mônica Beatriz Parolin, Giorgio Alfredo Pedroso Baretta, Silvania Klug Pimentel, Alexandre Coutinho Teixeira de Freitas, et al. Arquivos De Gastroenterologia, 2005
