Gaymard

@virpath.com

Virologie et Pathologie Humaine CIRI UCBL1 ENS INSERM U1111 CNRS
Université Claude bernard Lyon 1

Gaymard


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https://researchid.co/alexandregaymard

RESEARCH INTERESTS

Influenza viruses
93

Scopus Publications

7699

Scholar Citations

29

Scholar h-index

45

Scholar i10-index

Scopus Publications

  • Immune dysregulation through longitudinal lymphocyte trajectories and their clinical determinants in hospitalized COVID-19 patients
    José Pedro Cidade, Fabio Silvio Taccone, Luis Felipe Reyes, Laura Merson, Benjamin Lefevre, Barbara Wanjiru Citarella, Arie Zainul fatoni, Pedro Póvoa, , Sabriya Abdalasalam, Alaa Abdalfattah Abdalhadi, Naana Reyam Abdalla, Almthani Hamza Abdalrheem, Saedah Abdeewi, Esraa Hassan Abdelgaum, Mohamed Abdelhalim, Mohammed Abdelkabir, Sheryl Ann Abdukahil, Lamees Adil Abdulbaqi, Nurul Najmee Abdulkadir, Eman Abdulwahed, Rawad Abdunabi, Ryuzo Abe, Laurent Abel, Ahmed Mohammed Abodina, Amal Abrous, Kamal Abu Jabal, Nashat Abu Salah, Abdurraouf Abusalama, Subhash Acharya, Andrew Acker, Safia Adem, Manuella Ademnou, Neill K. J. Adhikari, Samuel Yaw Adu, Anthony Afum-Adjei Awuah, Melvin Agbogbatey, Saleh Al Ageel, Musaab Mohammed Ahmed, Aya Mustafa Ahmed, Zainab Ahmed Alaraji, Abdulrahman Ahmed Elhefnawy Enan, Reham Abdelhamid Ahmed Khalil, Ali Mostafa Ahmed Mohamed Abdelaziz, Kate Ainscough, Eka Airlangga, Tharwat Aisa, Ali Ait Hssain, Takako Akimoto, Ernita Akmal, Chika Akwani, Eman Al Qasim, Ahmed Alajeeli, Razi Alalqam, Zinah A. Alaraji, Safa Albatni, Angela Alberti, Tala Al-dabbous, Abdulkarim Aldoukali, Marta Alessi, Beatrice Alex, Kévin Alexandre, Abdulrahman Al-Fares, Asil Alflite, Huda Alfoudri, Qamrah Alhadad, Hoda Salem Alhaddad, Maali Khalid Mohamed Abdalla Alhasan, Hasan Alhouri, Ahmad Nabil Alhouri, Maha TagElser Mohammed Ali, Imran Ali, Yomna Ali Abdelghafar, Kazali Enagnon Alidjnou, Mahmoud Aljadi, Sarah Aljamal, Mohammed Alkahlout, Akram Alkaseek, Qabas Alkhafajee, Clotilde Allavena, Nathalie Allou, Abdulrahman Almjersah, Walaa Alrfaea, Moayad Alrifaee, Yousef Al-Sabaa, Entisar Alshareea, João Alves, João Melo Alves, Rita Alves, Joana Alves Cabrita, Maria Amaral, Amro Essam Amer, Nur Amira, Heidi Ammerlaan, Amos Amoako Adusei, John Amuasi, Roberto Andini, Claire Andrejak, Andrea Angheben, François Angoulvant, Séverine Ansart, Massimo Antonelli, Ardiyan Apriyana, Yaseen Arabi, Irene Aragao, Francisco Arancibia, Antonio Arcadipane, Patrick Archambault, Lukas Arenz, Jean-Benoît Arlet, Christel Arnold-Day, Lovkesh Arora, Elise Artaud-Macari, Diptesh Aryal, Motohiro Asaki, Angel Asensio, Elizabeth A. Ashley, Muhammad Ashraf, Muhammad Sheharyar Ashraf, Abir Ben Ashur, Franklin Asiedu-Bekoe, Namra Asif, Mohammad Asim, Grace Assi, Jean Baptiste Assie, Amirul Asyraf, Ahmed Atia, Minahel Atif, Asia Atif Abdelrhman Abdallahrs, Anika Atique, Moad Atlowly, Johann Auchabie, Hugues Aumaitre, Adrien Auvet, Ared Ayad, Ahmed Ayman Hassan Helmi, Laurène Azemar, Mohammed Azizeldin, Cecile Azoulay, Benjamin Bach, Antoine Bachelard, Delphine Bachelet, John Kenneth Baillie, J. Kevin Baird, Erica Bak, Agamemnon Bakakos, Nazreen Abu Bakar, Hibah Bileid Bakeer, Ashraf Bakri, Andriy Bal, Mohanaprasanth Balakrishnan, Alessandra Bandera, Firouzé Bani-Sadr, Nicholas Yuri Barbosa, Wendy S. Barclay, Saef Umar Barnett, Michaela Barnikel, Cleide Barrigoto, Marie Bartoli, Cheryl Bartone, Joaquín Baruch, Romain Basmaci, Muhammad Fadhli Hassin Basri, AbdAlkarim Batool, Denise Battaglini, Jules Bauer, Diego Fernando Bautista Rincon, Alexandra Bedossa, Ker Hong Bee, Husna Begum, Aleksandr Beljantsev, Beatriz Amorim Beltrão, Marine Beluze, Nicolas Benech, Lionel Eric Benjiman, Suzanne Bennett, Luís Bento, Jan-Erik Berdal, Delphine Bergeaud, José Luis Bernal Sobrino, Giulia Bertoli, Lorenzo Bertolino, Simon Bessis, Adam Betz, Sybille Bevilcaqua, Karine Bezulier, Amar Bhatt, Claudia Bianco, Sandra Bichoka, Farah Nadiah Bidin, Felwa Bin Humaid, Mohd Nazlin Bin Kamarudin, Muhannud Binnawara, Patrick Biston, Laurent Bitker, Pablo Blanco-Schweizer, Catherine Blier, Frank Bloos, Mathieu Blot, Filomena Boccia, Laetitia Bodenes, Debby Bogaert, Anne-Hélène Boivin, Ariel Bolanga, Isabela Bolaños, Pierre-Adrien Bolze, Aurelius Bonifasius, Joseph Bonney, Diogo Borges, Raphaël Borie, Elisabeth Botelho-Nevers, Lila Bouadma, Yasmine Bouaraba, Olivier Bouchaud, Sabelline Bouchez, Kévin Bouiller, Laurence Bouillet, Camile Bouisse, Latsaniphone Bountthasavong, Anne-Sophie Boureau, John Bourke, Maude Bouscambert, Aurore Bousquet, Marielle Boyer-Besseyre, Maria Boylan, Fernando Augusto Bozza, Axelle Braconnier, Luca Brazzi, Patrick Breen, David Brewster, Kathy Brickell, Tessa Broadley, Petra Bryda, Nina Buchtele, Polina Bugaeva, Marielle Buisson, Erlina Burhan, Donald Buri, Aidan Burrell, Ingrid G. Bustos, Denis Butnaru, André Cabie, Susana Cabral, Joana Cabrita, Eder Caceres, Cyril Cadoz, Rui Caetano Garcês, Mia Callahan, Jose Andres Calvache, João Camões, Paul Campbell, Josie Campisi, Cecilia Canepa, Mireia Cantero, Janice Caoili, Pauline Caraux-Paz, Filipa Cardoso, Sofia Cardoso, Nelson Cardoso, Filipe Cardoso, Simone Carelli, Nicolas Carlier, Thierry Carmoi, Gayle Carney, Inês Carqueja, Marie-Christine Carret, François Martin Carrier, Ida Carroll, Leonor Carvalho, Maire-Laure Casanova, Mariana Cascão, Siobhan Casey, José Casimiro, Bailey Cassandra, Silvia Castañeda, Guylaine Castor-Alexandre, Ana Catarino, François-Xavier Catherine, Roberto Cauda, Giulio- Giovanni Cavalli, Alexandros Cavayas, Adrian Ceccato, Ferruccio Ceriotti, Shelby Cerkovnik, Minerva Cervantes, Minerva Cervantes-Gonzalez, Muge Cevik, Anissa Chair, Catherine Chakveatze, Roberto Chalela, Adrienne Chan, Meera Chand, Jean-Marc Chapplain, Charlotte Charpentier, Julie Chas, Muhammad -Mobin Chaudry, Jonathan Samuel Chávez Iñiguez, Anjellica Chen, Matthew Pellan Cheng, Antoine Cheret, Thibault Chiarabini, Julian Chica, Suresh-Kumar Chidambaram, Leong Chin Tho, Catherine Chirouze, Hwa Jin Cho, Danoy Chommanam, Marie-Charlotte Chopin, Ting Soo Chow, Nathaniel Christy, Hiu Jian Chua, Jonathan Chua, José Miguel Cisneros Herreros, Anna Ciullo, Jennifer Clarke, Rolando Claure-Del Granado, Sara Clohisey, Peter David Coakley, Caitriona Cody, Megan Coles, Jennifer Coles, Gwenhaël Colin, Michael Collins, Pamela Combs, Jennifer Connolly, Marie Connor, Anne Conrad, Elaine Conway, Graham S. Cooke, Hugues Cordel, Amanda Corley, Sabine Cornelis, Arianne Joy Corpuz, Andrea Cortegiani, Grégory Corvaisier, Aoife Cotter, Sandrine Couffin-Cadiergues, Roxane Courtois, Stéphanie Cousse, Juthaporn Cowan, Rachel Cregan, Charles Crepy D Orleans, Cosimo Cristella, Gloria Crowl, Jonathan Crump, Claudina Cruz, Juan Luis Cruz Bermúdez, Jaime Cruz Rojo, Marc Csete, Ailbhe Cullen, Matthew Cummings, Gerard Curley, Elodie Curlier, Colleen Curran, Ana da Silva Filipe, Charlene da Silveira, Al-Awwab Dabaliz, Andrew Dagens, Darren Dahly, Peter Daley, Zaina Dalloul, Jo Dalton, Heidi Dalton, Seamus Daly, Juliana Damas, Joycelyn Dame, Cammandji Damien, Nick Daneman, Jorge Dantas, Menno de Jong, Fernando De La Calle Prieto, Gillian de Loughry, Diego de Mendoza, Etienne de Montmollin, Ana Isabel de Pinho Oliveira, Rosanna de Rosa, Thushan de Silva, Peter de Vries, Alexa Debard, Bianca DeBenedictis, Marie-Pierre Debray, Nathalie DeCastro, William Dechert, Romain Decours, Eve Defous, Isabelle Delacroix, Alexandre Delamou, Karen Delavigne, Nathalie M. Delfos, Andrea Dell Amore, Christelle Delmas, Pierre Delobel, Ismaila Deme, Elisa Demonchy, Emmanuelle Denis, Dominique Deplanque, Pieter Depuydt, Diane Descamps, Mathilde Desvallées, Santi Dewayanti, Pathik Dhangar, Alpha Diallo, Souleymane Taran Diallo, Sylvain Diamantis, Andrea Dias, André Dias, Juan Jose Diaz, Priscila Diaz, Rodrigo Diaz, Kévin Didier, Jean-Luc Diehl, Aurélien Dinh, Alphonsine Diouf, Yael Dishon, Cedric Djadda, Félix Djossou, Nikita Dobremel, Annemarie B. Docherty, Helen Doherty, Arjen M. Dondorp, Christl A. Donnelly, Yoann Donohue, Sean Donohue, Peter Doran, Céline Dorival, Eric D Ortenzio, Phouvieng Douangdala, James Joshua Douglas, Nathalie Dournon, Thomas Drake, Aoife Driscoll, Ibrahim Kwaku Duah, Vincent Dubee, François Dubos, Audrey Dubot-Pérès, Alexandre Ducancelle, Susanne Dudman, Abhijit Duggal, Paul Dunand, Jake Dunning, Mathilde Duplaix, Emanuele Durante-Mangoni, Lucian Durham, Bertrand Dussol, Xavier Duval, Anne Margarita Dyrhol-Riise, Sim-Choon Ean, Marco Echeverria-Villalobos, Michael Edelstein, Khadeja Ehzaz, Carla Eira, Mohammed El Sanharawi, Subbarao Elapavaluru, Mohammad Elbahnasawy, Brigitte Elharrar, Hamida ELMagrahi, Lauren Eloundou, Philippine Eloy, Tarek Elshazly, Wafa Elsokni, Aml Ahmed Eltayeb, Iqbal Elyazar, Zarief Kamel Emad, Hussein Embarek, Isabelle Enderle, Tomoyuki Endo, Gervais Eneli, Chan Chee Eng, Ilka Engelmann, Vincent Enouf, Olivier Epaulard, Haneen Esaadi, Mariano Esperatti, Catarina Espírito Santo, Marina Esposito-Farese, Rachel Essaka, João Estevão, Manuel Etienne, Anna Greti Everding, Mirjam Evers, Marc Fabre, Isabelle Fabre, Asgad Osman Abdalla Fadlalla, Amna Faheem, Arabella Fahy, Cameron J. Fairfield, Komal Fareed, Pedro Faria, Ahmed Farooq, Hanan Fateena, Salem Fatima, Arie Zainul Fatoni, Karine Faure, Raphaël Favory, Mohamed Fayed, Niamh Feely, Eoin Feeney, Susana Fernandes, Jorge Fernandes, Marília Andreia Fernandes, François-Xavier Ferrand, Joana Ferrão, Mário Ferraz, Isabel Ferreira, Sílvia Ferreira, Benigno Ferreira, Bernardo Ferreira, Nicolas Ferriere, Valentina Ferroni, Céline Ficko, Thomas Flament, Tom Fletcher, Aline-Marie Florence, Letizia Lucia Florio, Deirdre Flynn, Jean Foley, Victor Fomin, Patricia Fontela, Simon Forsyth, Denise Foster, Giuseppe Foti, Berline Fotso, Erwan Fourn, Robert A. Fowler, Marianne Fraher, Diego Franch-Llasat, Pierre Frange, John F. Fraser, Christophe Fraser, Ricardo Fritz, Stéphanie Fry, Nora Fuentes, G. Argin, Valérie Gaborieau, Rostane Gaci, Massimo Gagliardi, Jean-Charles Gagnard, Amandine Gagneux-Brunon, Sérgio Gaião, Linda Gail Skeie, Adham Mohamed Galal Mohamed Ramadan, Phil Gallagher, Carrol Gamble, Yasmin Gani, Arthur Garan, Rebekha Garcia, Noelia García Barrio, Julio Garcia Rodriguez, Julia Garcia-Diaz, Esteban Garcia-Gallo, Denis Garot, Valérie Garrait, Anatoliy Gavrylov, Alexandre Gaymard, Johannes Gebauer, Eva Geraud, Louis Gerbaud Morlaes, Nuno Germano, Malak Ghemmeid, Praveen Kumar Ghisulal, Jade Ghosn, Marco Giani, Carlo Giaquinto, Séverine Gibowski, Tristan Gigante, Guillermo Giordano, Michelle Girvan, Valérie Gissot, Gezy Giwangkancana, Daniel Glikman, Petr Glybochko, Eric Gnall, Geraldine Goco, François Goehringer, Siri Goepel, Jean-Christophe Goffard, Jin Yi Goh, Brigitta Golács, Jonathan Golob, Rui Gomes, Joan Gómez-Junyent, Marie Gominet, Alicia Gonzalez, Patricia Gordon, Isabelle Gorenne, Laure Goubert, Cécile Goujard, Tiphaine Goulenok, Margarite Grable, Jeronimo Graf, Edward Wilson Grandin, Pascal Granier, Giacomo Grasselli, Christopher A. Green, William Greenhalf, Segolène Greffe, Domenico Luca Grieco, Matthew Griffee, Fiona Griffiths, Ioana Grigoras, Albert Groenendijk, Fassou Mathias Grovogui, Heidi Gruner, Yusing Gu, Jérémie Guedj, Martin Guego, Anne-Marie Guerguerian, Daniela Guerreiro, Romain Guery, Anne Guillaumot, Laurent Guilleminault, Thomas Guimard, Daniel Haber, Ali Hachemi, Abdurrahman Haddud, Nadir Hadri, Wael Hafez, Fakhir Raza Haidri, Fatima Mhd Rida Hajij, Sheeba Hakak, Matthew Hall, Sophie Halpin, Shaher Hamdan, Abdelhafeez Hamdi, Ansley Hamer, Raph L. Hamers, Rebecca Hamidfar, Naomi Hammond, Terese Hammond, Lim Yuen Han, Matly Hanan, Rashan Haniffa, Kok Wei Hao, Hayley Hardwick, Ewen M. Harrison, Alan Hartman, Mohd Shahnaz Hasan, Mohammad Ali Nabil Hasan, Sulieman Hasan, Madiha Hashmi, Junaid Hashmi, Amoni Hassan, Ebtisam Hassanin, Muhammad Hayat, Ailbhe Hayes, Leanne Hays, Lars Heggelund, Ahmed Helmi, Ross Hendry, Martina Hennessy, Aquiles Rodrigo Henriquez-Trujillo, Maxime Hentzien, Diana Hernandez, Andrew Hershey, Astarini Hidayah, Eibhlin Higgins, Samuel Hinton, Hiroaki Hiraiwa, Maya Hites, Hikombo Hitoto, Yi Bin Ho, Antonia Ho, Alexandre Hoctin, Isabelle Hoffmann, Wei Han Hoh, Oscar Hoiting, Jan Cato Holter, Peter Horby, Juan Pablo Horcajada, Mabrouka Houderi, Stuart Houltham, Jimmy Ming-Yang Hsu, Jean-Sébastien Hulot, Abby Hurd, Iqbal Hussain, Aliae Mohamed Hussein, Mahmood Hussein, Fatima Ibrahim, Bashir Ibran, Samreen Ijaz, M. Arfan Ikram, Patrick Imbert, Rana Imran Sikander, Hugo Inácio, Carmen Infante Dominguez, Yun Sii Ing, Mariachiara Ippolito, Vera Irawany, Sarah Isgett, Tiago Isidoro, Nadiah Ismail, Margaux Isnard, Junji Itai, Danielle Jaafar, Salma Jaafoura, Hamza Jaber, Julien Jabot, Clare Jackson, Victoria Janes, Stéphane Jaureguiberry, Jeffrey Javidfar, Denise Jaworsky, Florence Jego, Anilawati Mat Jelani, Synne Jenum, Ruth Jimbo-Sotomayor, Ong Yiaw Joe, Ruth Noemí Jorge García, Cédric Joseph, Mark Joseph, Evelyn Joson, Mercé Jourdain, Philippe Jouvet, Anna Jung, Dafsah Juzar, Ouifiya Kafif, Florentia Kaguelidou, Neerusha Kaisbain, Sabrina Kali, Smaragdi Kalomoiri, Muhammad Aisar Ayadi Kamaluddin, Armand Saloun Kamano, Zul Amali Che Kamaruddin, Nadiah Kamarudin, Darshana Hewa Kandamby, Kong Yeow Kang, Dyah Kanyawati, Mohamed Karghul, Pratap Karpayah, Christiana Kartsonaki, Daisuke Kasugai, Kevin Katz, Christy Kay, Lamees Kayyali, Seán Keating, Aoife Kelly, Niamh Kelly, Sadie Kelly, Yvelynne Kelly, Maeve Kelsey, Sommay Keomany, Maeve Kernan, Younes Kerroumi, Sharma Keshav, Shams Khail, Sarah Khaled, Imrana Khalid, Zineb Khalil, Antoine Khalil, Irfan Khan, Sushil Khanal, Michelle E. Kho, Denisa Khoo, Saye Khoo, Ryan Khoo, Muhammad Nasir Khoso, Khor How Kiat, Yuri Kida, Peter Kiiza, Beathe Kiland Granerud, Anders Benjamin Kildal, Jae Burm Kim, Antoine Kimmoun, Paul Klenerman, Gry Kloumann Bekken, Stephen R. Knight, Robin Kobbe, Chamira Kodippily, Sabin Koirala, Stephanie Kouba, Karifa Kourouma, Mohamed Lamine Kourouma, Karolina Krawczyk, Ali Kredan, Vinothini Krishnan, Sudhir Krishnan, Oksana Kruglova, Anneli Krund, Pei Xuan Kuan, Ganesh Kumar, Deepali Kumar, Dinesh Kuriakose, Ethan Kurtzman, Demetrios Kutsogiannis, Galyna Kutsyna, Sylvie Kwedi, Konstantinos Kyriakoulis, Marie Lachatre, Karine Lacombe, Marie Lacoste, John G. Laffey, Nadhem Lafhej, Marie Lagrange, Fabrice Laine, Olivier Lairez, Antonio Lalueza, Marc Lambert, Marie Langelot-Richard, Vincent Langlois, Cédric Laouénan, Samira Laribi, Delphine Lariviere, Jamaica Laroza, Stéphane Lasry, Youssef Latifeh, Odile Launay, Didier Laureillard, Yoan Lavie-Badie, Andy Law, Teresa Lawrence, Minh Le, Clément Le Bihan, Cyril Le Bris, Georges Le Falher, Lucie Le Fevre, Quentin Le Hingrat, Marion Le Maréchal, Soizic Le Mestre, Guillaume Le Meut, Gwenaël Le Moal, Vincent Le Moing, Hervé Le Nagard, Ema Leal, Marta Leal Santos, Yi Lin Lee, Heng Gee Lee, James Lee, Biing Horng Lee, Todd C. Lee, Gary Leeming, Bénédicte Lefebvre, Laurent Lefebvre, Benjamin Lefèvre, Sylvie LeGac, Merili-Helen Lehiste, Jean-Daniel Lelievre, François Lellouche, Adrien Lemaignen, Véronique Lemee, Anthony Lemeur, Gretchen Lemmink, Ha Sha Lene, Jenny Lennon, Marc Leone, Tanel Lepik, Quentin Lepiller, François-Xavier Lescure, Mathieu Lesouhaitier, Andrew Letizia, Sophie Letrou, Bruno Levy, Yves Levy, Claire Levy-Marchal, Katarzyna Lewandowska, Gianluigi Li Bassi, Janet Liang, Geoffrey Liegeon, Wei Shen Lim, Kah Chuan Lim, Chantre Lima, Lim Lina, Bruno Lina, Andreas Lind, Guillaume Lingas, Sylvie Lion-Daolio, Keibun Liu, Marine Livrozet, Patricia Lizotte, Antonio Loforte, Navy Lolong, Leong Chee Loon, Diogo Lopes, Dalia Lopez-Colon, Jose W. López-Revilla, Anthony L. Loschner, Paul Loubet, Bouchra Loufti, Guillame Louis, Silvia Lourenco, Lee Lee Low, Jia Shyi Loy, Carlos Lumbreras Bermejo, Carlos M. Luna, Olguta Lungu, Miles Lunn, Liem Luong, Nestor Luque, Dominique Luton, Olavi Maasikas, Moïse Machado, Sara Machado, Gabriel Macheda, Claire Madelaine, Guillermo Maestro de la Calle, Rafael Mahieu, Sophie Mahy, Ana Raquel Maia, Lars S. Maier, Oumou Maiga Ascofare, Mylène Maillet, Nimisha Abdul Majeed, Maximilian Malfertheiner, Nadia Malik, Wajeeha Malik, Dayana Malla, Paddy Mallon, Fernando Maltez, Denis Malvy, Victoria Manda, Laurent Mandelbrot, Frank Manetta, Julie Mankikian, Edmund Manning, Aldric Manuel, Veronika Maráczi, Samuel Markowicz, Ana Marques, Megan Marshal, John Marshall, Dori-Ann Martin, Emily Martin, Guillaume Martin-Blondel, F. Eduardo Martinez, Ignacio Martin-Loeches, Martin Martinot, Alejandro Martín-Quiros, João Martins, Nuno Martins, Ana Martins, Gennaro Martucci, Olga Martynenko, Eva Miranda Marwali, Marsilla Marzukie, David Maslove, Sabina Mason, Sobia Masood, Moise Massoma, Palmer Masumbe, Mohd Basri Mat Nor, Moshe Matan, Christina Mathew, Mathieu Mattei, Laurence Maulin, Juergen May, Mayfong Mayxay, Thierry Mazzoni, Lisa Mc Sweeney, Colin McArthur, Peter McCanny, Aine McCarthy, Colin McCloskey, Rachael McConnochie, Sherry McDermott, Sarah E. McDonald, Natalie McEvoy, Allison McGeer, Kenneth A. McLean, Paul McNally, Bairbre McNicholas, Edel Meaney, Cécile Mear-Passard, Maggie Mechlin, Omar Mehkri, Ferruccio Mele, João João Mendes, Kusum Menon, France Mentré, Alexander J. Mentzer, Emmanuelle Mercier, Antoine Merckx, Mayka Mergeay-Fabre, António Mesquita, Osama Metwally, Agnès Meybeck, Dan Meyer, Mehdi Mezidi, Isabelle Michelet, Efstathia Mihelis, Vladislav Mihnovit, Duha Milad Abdullah, Jennene Miller, Hugo Miranda-Maldonado, Nor Arisah Misnan, Tahira Jamal Mohamed, Nouralsabah Mohamed, Nik Nur Eliza Mohamed, Alaa Mohamed Ads, Ahmed Reda Mohamed Elsayed Abdelhalim, Shrouk Fawze Mohammed Mostafa, Omer Abdullah Mohammedelhassan, Saad A. Moharam, Diana Molino, Elena Molinos, Brenda Molloy, Geraldine Moloney, Mary Mone, Agostinho Monteiro, Claudia Montes, Giorgia Montrucchio, Sarah Moore, Shona C. Moore, Lina Morales Cely, Marwa Morgom, Lucia Moro, Ana Motos, Clara Mouton Perrot, Julien Moyet, Suleiman Haitham Mualla, Aisha Kalsoom Mufti, Ng Yong Muh, Mo nes Muhaisen, Dzawani Muhamad, Jimmy Mullaert, Karl Erik Müller, Fredrik Müller, Daniel Munblit, Syed Muneeb Ali, Laveena Munshi, Aisling Murphy, Patrick Murray, Marlène Murris, Srinivas Murthy, Himed Musaab, Dana Mustafa, Dimitra Melia Myrodia, Farah Nadia Mohd-Hanafiah, Dave Nagpal, Blanka Nagybányai-Nagy, Herwin Nanda Boudoin, Mangala Narasimhan, Adel Gerges Nassif Metri, Nadège Neant, Coca Necsoi, Nikita Nekliudov, Matthew Nelder, Erni Juwita Nelwan, Emily Neumann, Wing Yiu Ng, Pauline Yeung Ng, Anthony Nghi, Duc Nguyen, Orna Ni Choileain, Niamh Ni Leathlobhair, Nerissa Niba, Alistair D. Nichol, Nurul Amani Mohd Noordin, Nurul Faten Izzati Norharizam, Mahdad Noursadeghi, Adam Nowinski, Saad Nseir, Leonard Numfor, Nurnaningsih Nurnaningsih, Dwi Utomo Nusantara, Elsa Nyamankolly, Fionnuala O. Brien, Annmarie O. Callaghan, Annmarie O Callaghan, Giovanna Occhipinti, Sarah O Connell, Derbrenn OConnor, Max O Donnell, Ebenezer Oduro-Mensah, Tawnya Ogston, Takayuki Ogura, Tak-Hyuk Oh, Sophie O Halloran, Katie O Hearn, Sally-Ann Ohene, Shinichiro Ohshimo, Agnieszka Oldakowska, João Oliveira, Joseph Oliver-Commey, Piero L. Olliaro, Inge Christoffer Olsen, Alsarrah Ali Mohammed Omer, Pierre Ondobo, David S. Y Ong, Jee Yan Ong, Wilna Oosthuyzen, Peter Openshaw, Saijad Orakzai, Claudia Milena Orozco-Chamorro, Mohamed Osama Elsayed Soliman, Linda O Shea, Miriam O Sullivan, Siti Zubaidah Othman, Eman Othman, Rachida Ouissa, Christian Owoo, Micheal Owusu, Ama Akyampomaa Owusu-Asare, Eric Oziol, Patricia Pacheco, Maïder Pagadoy, Justine Pages, Massimo Palmarini, Carlo Palmieri, Giovanna Panarello, Prasan Kumar Panda, Hem Paneru, Lai Hui Pang, Mauro Panigada, Nathalie Pansu, Aurélie Papadopoulos, Rachael Parke, Melissa Parker, Bruno Pastene, Fabian Patauner, Mohan Dass Pathmanathan, Luís Patrão, Patricia Patricio, Lisa Patterson, Christelle Paul, Mical Paul, Jorge Paulos, William A. Paxton, Jean-François Payen, Sandra L. Peake, Kalaiarasu Peariasamy, Miguel Pedrera Jiménez, Giles J. Peek, Florent Peelman, Nathan Peiffer-Smadja, Vincent Peigne, Mare Pejkovska, Paolo Pelosi, Rui Pereira, Daniel Perez, Thomas Perpoint, Antonio Pesenti, Lenina Pessey, Vincent Pestre, Lenka Petrou, Michele Petrovic, Ventzislava Petrov-Sanchez, Gilles Peytavin, Richard Odame Philips, Ooyanong Phonemixay, Soulichanya Phoutthavong, Michael Piagnerelli, Gilles Pialoux, Olivier Picone, Maria de Piero, Carlos Pimentel, Raquel Pinto, Catarina Pires, Lionel Piroth, Ayodhia Pitaloka, Chiara Piubelli, Riinu Pius, Simone Piva, Laurent Plantier, Hon Shen Png, Julien Poissy, Ryadh Pokeerbux, Maria Pokorska-Spiewak, Sergio Poli, Georgios Pollakis, Diane Ponscarme, Jolanta Popielska, Diego Bastos Porto, Andra-Maris Post, Douwe F. Postma, Valérie Pourcher, Diana Póvoas, Jeff Powis, Sofia Prapa, Viladeth Praphasiri, Sébastien Preau, Christian Prebensen, Jean-Charles Preiser, Anton Prinssen, Gamage Dona Dilanthi Priyadarshani, Lucia Proença, Sravya Pudota, Bambang Pujo Semedi, Peter Puplampu, Gregory Purcell, Luisa Quesada, Víctor Quirós González, Else Quist-Paulsen, Mohammed Quraishi, Fadi Qutishat, Christian Rabaud, Ebenezer Rabindrarajan, Aldo Rafael, Marie Rafiq, Abdelrahman Ragab, Mutia Rahardjani, Rozanah Abd Rahman, Ahmad Kashfi Haji Ab Rahman, Fernando Rainieri, Giri Shan Rajahram, Pratheema Ramachandran, José Ramalho, Ahmad Afiq Ramli, Grazielle Viana Ramos, Muhammad Asim Rana, Rajavardhan Rangappa, Hervé Raoul, Christophe Rapp, Thalha Rashan, Aasiyah Rashan, Ghulam Rasheed, Menaldi Rasmin, Indrek Rätsep, Cornelius Rau, Tharmini Ravi, Andre Real, Stanislas Rebaudet, Sarah Redl, Brenda Reeve, Dag Henrik Reikvam, Renato Reis, Jonathan Remppis, Hongru Ren, Hanna Renk, Anne-Sophie Resseguier, Matthieu Revest, Oleksa Rewa, Maria Ines Ribeiro, Denise Richardson, David Richardson, Laurent Richier, Siti Nurul Atikah Ahmad Ridzuan, Asgar Rishu, Patrick Rispal, Karine Risso, Maria Angelica Rivera Nuñez, Chiara Robba, André Roberto, David L. Robertson, Olivier Robineau, Ferran Roche-Campo, Paola Rodari, Simão Rodeia, Bernhard Roessler, Claire Roger, Amanda Rojek, Roberto Roncon-Albuquerque, Mélanie Roriz, Manuel Rosa-Calatrava, Michael Rose, Dorothea Rosenberger, Andrea Rossanese, Matteo Rossetti, Patrick Rossignol, Carine Roy, Benoît Roze, Desy Rusmawatiningtyas, Clark D. Russell, Maeve Ryan, Aleksander Rygh Holten, Isabela Saba, Sairah Sadaf, Musharaf Sadat, Valla Sahraei, Abdurraouf Said, Fodé Bangaly Sako, Moamen Salah, Ali Alaa Salah Eldin Mohamed Abbas, Nawal Salahuddin, Leonardo Salazar, Mohammed Saleh Alyasiri, Gabriele Sales, Charlotte Salmon Gandonniere, Hélène Salvator, Yehia Samir Shaaban Aly Orabi, Olivier Sanchez, Emely Sanchez, Angel Sanchez-Miralles, Gyan Sandhu, Zulfiqar Sandhu, Pierre-François Sandrine, Oana Săndulescu, Marlene Santos, Lurdes Santos, Shirley Sarfo-Mensah, Bruno Sarmento Banheiro, Benjamine Sarton, Sree Satyapriya, Rumaisah Satyawati, Yen Tsen Saw, Justin Schaffer, Tjard Schermer, Arnaud Scherpereel, Marion Schneider, János Schnur, Michael Schwameis, Gary Schwartz, Janet T. Scott, Nicholas Sedillot, Tamara Seitz, Mageswari Selvarajoo, Malcolm G. Semple, Rasidah B. T. Senian, Eric Senneville, Claudia Sepulveda, Tânia Sequeira, Ary Serpa Neto, Pablo Serrano Balazote, Ellen Shadowitz, Syamin Asyraf Shahidan, Laila Shalabi, Haitam Shames, Anuraj Shankar, Shaikh Sharjeel, Pratima Sharma, Catherine A. Shaw, Victoria Shaw, John Robert Sheenan, Rajesh Mohan Shetty, Mohiuddin Shiekh, Nobuaki Shime, Keiki Shimizu, Hiroaki Shimizu, Sally Shrapnel, Hoi Ping Shum, Nassima Si Mohammed, Ng Yong Siang, Jeanne Sibiude, Bountoy Sibounheuang, Louise Sigfrid, Piret Sillaots, Maria Joao Silva, Rogério Silva, Catarina Silva, Benedict Sim Lim Heng, Wai Ching Sin, Punam Singh, Mahendra Singh, Pompini Agustina Sitompul, Karisha Sivam, Vegard Skogen, Benjamin Smood, Coilin Smyth, Dominic So, Tze Vee Soh, Tom Solomon, Joshua Solomon, Emily Somers, Agnès Sommet, Rima Song, Tae Song, Jack Song Chia, Albert Sotto, Edouard Soum, Ana Chora Sousa, Marta Sousa, Maria Sousa Uva, Vicente Souza-Dantas, Mamadou Saliou Sow, Alexandra Sperry, Elisabetta Spinuzza, B. P. Sanka Ruwan Sri Darshana, Shiranee Sriskandan, Sarah Stabler, Thomas Staudinger, Stephanie-Susanne Stecher, Trude Steinsvik, Ymkje Stienstra, Birgitte Stiksrud, Eva Stolz, Amy Stone, Adrian Streinu-Cercel, Anca Streinu-Cercel, David Stuart, Decy Subekti, Jacky Y. Suen, Prasanth Sukumar, Charlotte Summers, Dubravka Supic, Deepashankari Suppiah, Magdalena Surovcová, Atie Suwarti, Andrey Svistunov, Sarah Syahrin, Augustina Sylverken, Konstantinos Syrigos, Shirin Tabrizi, Fabio S. Taccone, Shahdattul Mawarni Taib, Ewa Talarek, Sara Taleb, Cheikh Talla, Jelmer Talsma, Maria Lawrensia Tampubolon, Yan Chyi Tan, Kim Keat Tan, Taku Tanaka, Huda Taqdees, Coralie Tardivon, Yousef Tarek Kamal Mostafa, Ali Tarhabat, Pierre Tattevin, M. Azhari Taufik, Hassan Tawfik, Tze Yuan Tee, João Teixeira, Sze Kye Teoh, Vanessa Teotonio, François Téoulé, Olivier Terrier, Hubert Tessier-Grenier, Adrian Tey, Alif Adlan Mohd Thabit, Zhang Duan Tham, Suvintheran Thangavelu, Elmi Theron, Vincent Thibault, Simon-Djamel Thiberville, Benoît Thill, Jananee Thirumanickam, Shaun Thompson, Emma C. Thomson, David Thomson, Mathew Thorpe, Surain Raaj ThangaThurai, Ryan Thwaites, Paul Tierney, Vadim Tieroshyn, Peter S. Timashev, Jean-François Timsit, Noémie Tissot, Jordan Zhien Yang Toh, Maria Toki, Kristian Tonby, Sia Loong Tonnii, Marta Torre, Antoni Torres, Margarida Torres, Rosario Maria Torres Santos-Olmo, Hernando Torres-Zevallos, Aboubacar Tounkara, Michael Towers, Fodé Amara Traoré, Tony Trapani, Cécile Tromeur, Ioannis Trontzas, Jeanne Truong, Christelle Tual, Sarah Tubiana, Helen Tuite, Alexis F. Turgeon, Lance C. W. Turtle, Anders Tveita, Pawel Twardowski, Makoto Uchiyama, P. G. Ishara Udayanga, Andrew Udy, Roman Ullrich, Alberto Uribe, Asad Usman, Timothy M. Uyeki, Cristinava Vajdovics, Luís Val-Flores, Marcel van den Berge, Machteld van der Feltz, Peter Van der Voort, Sylvie Van Der Werf, Eric van Gorp, Laura van Gulik, Jarne van Hattem, Carolien van Netten, Frank van Someren Gréve, Gitte van Twillert, Hugo van Willigen, Noémie Vanel, Michael Varrone, Shoban Raj Vasudayan, Charline Vauchy, Shaminee Veeran, Aurélie Veislinger, Sara Ventura, Annelies Verbon, César Vieira, Deepak Vijayan, Judit Villar, Andrea Villoldo, Manivanh Vongsouvath, Fanny Vuotto, Suhaila Abdul Wahab, Noor Hidayu Wahab, Nadirah Abdul Wahid, Marina Wainstein, Laura Walsh, Steve Webb, Tan Pei Wen, Sanne Wesselius, Murray Wham, Bryan Whelan, Nicole White, Aurélie Wiedemann, Surya Otto Wijaya, Virginie Williams, Patricia J. Williams, Bailey Williams, Evert-Jan Wils, Karolina Witt, Jessica Wittman, Xin Ci Wong, Yew Sing Wong, Teck Fung Wong, Calvin Wong, Lim Saio Xian, Ioannis Xynogalas, Siti Rohani Binti Mohd Yakop, Masaki Yamazaki, Elizabeth Yarad, Yazdan Yazdanpanah, Nicholas Yee- Liang Hing, Abdelrahman Yehia Mahmoud Abdelaal, Cécile Yelnik, Chian Hui Yeoh, Touxiong Yiaye, Hodane Yonis, Obada Yousif, Saptadi Yuliarto, Akram Zaaqoq, Marion Zabbe, Masliza Zahid, Nor Zaila Binti Zaidan, Maria Zambon, Miguel Zambrano, Alberto Zanella, Konrad Zawadka, Nurul Zaynah, Hiba Zayyad, Alexander Zoufaly, David Zucman
    Intensive Care Medicine Experimental, 2026
    Objective Immune dysregulation plays a pivotal role in the pathophysiology of sepsis and COVID-19, with lymphopenia emerging as a consistent marker of severity and poor prognosis. However, most existing studies have assessed lymphocyte counts at isolated time points, limiting insights into their temporal behavior and prognostic value. The dynamics of lymphocyte recovery or persistence of lymphopenia remain largely unexplored in large populations, as well as the impact of adjunctive therapies such as corticosteroids. We hypothesized that the persistence or recovery of lymphopenia may be key to understanding disease progression and predicting outcomes. Using the multinational ISARIC cohort, we investigated longitudinal lymphocyte trajectories in hospitalized patients and the clinical determinants associated with their evolution over time. Methods We conducted a multinational prospective observational cohort study using data from the ISARIC-WHO Clinical Characterization Protocol. Patients with confirmed SARS-CoV-2 infection and at least four lymphocyte measurements during the first 28 days of hospitalization were included. We analyzed lymphocyte trajectories, Cox regression survival analyses and multivariable linear regression modelling. We also applied multistate models and joint modeling to assess the association between lymphocyte trajectories and 28-day mortality, incorporating corticosteroid use as a time-varying covariate. Results Of 945,317 screened patients, 231,933 hospitalized adults with confirmed COVID-19 and sufficient lymphocyte data were included, with 56.6% classified as lymphopenic. Lymphopenia was independently associated with higher rates of ICU admission, organ support, and in-hospital mortality (OR = 1.52, 95% CI 1.48–1.55), and lower absolute lymphocyte counts were strongly linked to worse survival in adjusted Cox models (HR = 1.33 per 1 × 10⁹ cells/L decrease, 95% CI 1.28–1.38). Multistate modeling revealed that lymphopenic patients had a significantly higher daily transition rate to death and a shorter duration in that immune state, while corticosteroid exposure was associated with an increased likelihood of entering and remaining in lymphopenia. Joint modeling identified age, sex, and corticosteroid use as significant predictors of lower lymphocyte trajectories over time, with distinct dynamics between survivors and non-survivors. Conclusion Lymphopenia was common and strongly associated with worse outcomes in hospitalized COVID-19 patients, with impaired recovery particularly evident in those receiving corticosteroids. These findings highlight the value of lymphocyte monitoring to inform tailored immunomodulatory strategies in sepsis and severe viral infections.
  • Efficacy, safety, pharmacokinetics, immunogenicity, and serum neutralizing activity of AZD7442 (tixagevimab-cilgavimab) in patients hospitalized with COVID-19: long-term results from the DisCoVeRy trial
    Clément R. Massonnaud, Nathan Peiffer-Smadja, Pascal Poignard, Simon Jamard, François Goehringer, François Danion, Jean Reignier, Nathalie de Castro, Denis Garot, Eva Larranaga Lapique, Karine Lacombe, Violaine Tolsma, Emmanuel Faure, Denis Malvy, Thérèse Staub, Johan Courjon, France Cazenave-Roblot, Anne Ma Dyrhol Riise, Paul Leturnier, Guillaume Martin-Blondel, Claire Roger, Karolina Akinosoglou, Vincent Le Moing, Lionel Piroth, Pierre Sellier, Xavier Lescure, Marius Trøseid, Philippe Clevenbergh, Olav Dalgard, Sébastien Gallien, Marie Gousseff, Paul Loubet, Fanny Vardon-Bounes, Clotilde Visée, Leila Belkhir, Élisabeth Botelho-Nevers, André Cabié, Anastasia Kotanidou, Fanny Lanternier, Elisabeth Rouveix-Nordon, Susana Silva, Guillaume Thiery, Guislaine Carcelain, Alpha Diallo, Noémie Mercier, Vida Terzić, Maude Bouscambert-Duchamp, Alexandre Gaymard, Grégory Destras, Laurence Josset, Drifa Belhadi, Nicolas Billard, Jérémie Guedj, Thi-Hong-Lien Han, Sandrine Couffin-Cadiergues, Aline Dechanet, Christelle Delmas, Hélène Esperou, Claire Fougerou-Leurent, Soizic Le Mestre, Annabelle Métois, Marion Noret, Isabelle Bally, Sebastián Dergan-Dylon, Sarah Tubiana, Ouifiya Kalif, Nathalie Bergaud, Benjamin Leveau, Joe Eustace, Richard Greil, Edit Hajdu, Monika Halanova, Jose-Artur Paiva, Anna Piekarska, Jesus Rodriguez Baño, Kristian Tonby, Milan Trojánek, Sotirios Tsiodras, Serhat Unal, Charles Burdet, Dominique Costagliola, Yazdan Yazdanpanah, France Mentré, Florence Ader, Maya Hites, Sandrine Couffin-Cadièrgues, Hélène Espérou, Investigators, Alexander Egle, Alexander Egle, Richard Greil, Michael Grundbichler, Volker Hauck, Lukas Ratzinger, Felix De Bièvre, Maya Hites, Frederique Jacobs, Eva Larranaga, Englert Pierre, Gil Verschelden, Philippe Clevenbergh, Sophie Leemans, Evelyne Maillart, Leila Belkhir, Julien De Greef, Jean Cyr Yombi, Ides Colin, Clotilde Visée, Mathias Leys, Pieter Samaey, Janneke Cox, Peter Messiaen, Jeroen Van der Hilst, Karlijn Van Halem, Zula Badaev, Vyacheslav Grebenyuk, Milan Trojanek, Veronika Bednarova, Anna Chaloupka, Katarina Dolezalova, Andrej Nagy, Michal Rezek, Filip Soucek, Alzbeta Trckova, Adeline Bauvois, Cyril Charron, Laetitia Coutte, Guillaume Geri, Mathieu Godement, Segolene Greffe, Romain Jouffroy, Edouard Jullien, Jean-Emmanuel Kahn, Marion Pepin, Matthieu Petit, Elisabeth Rouveix-Nordon, Claire Andrejak, Damien Basille, Cedric Joseph, Jean Philippe Lanoix, Sylvie Lion, Jean-Luc Schmit, Sandrine Soriot-Thomas, Carine Belzunce, David Bougon, Pierre-Alain Charretier, Renaud Chouquer, Didier Dorez, Etienne Escudier, Samuel Gay, Serge Hautefeuille, Cecile Janssen, Albrice Levrat, Gabriel Macheda, Mylene Maillet, Aldric Manuel, Audrey Merlet, Michel Muller, Sylvain Panh, Emilie Piet, Marion Rougon, Michel Sirodot, Violaine Tolsma, Caroline Varache, Vitrat Vitrat, Kevin Bouiller, Catherine Chirouze, Dejan Ilic, Jean-Christophe Navellou, Noemie Tissot, Simon Bessi, Christelle Chantalat, Stephane Jaureguiberry, Antoine Bachelard, Chloe Bertin, Lio Collias, Odile Fleurot, Nathan Peiffer-Smadja, Valentina Isernia, Xavier Lescure, Bastien Mallo, Caroline Proux, Yazdan Yazdanpanah, Charles Cazanave, Philippe Boyer, Alexandre Boyer, Hoang-Nam Bui, Cedric Carrier, Benjamin Clouzeau, Arnaud Desclaux, Maylis Ducours, Cedric Gil-Jardine, Alexandre Gros, Didier Gruson, Julie Leitao, Maelig Lescure, Denis Malvy, Didier Neau, Maxime Poteau, Charline Sazio, Clara Bourrachot, Violaine Corbin, Kevin Grapin, Christine Jacomet, Henri Laurichesse, Olivier Lesens, Natacha Mrozek, Leo Sauvat, Aurelien Simon, Clement Theis, Magali Vidal, Simon Gravier, Ciprian Ion, Damien Kayser, Martin Martinot, Mahsa Mohseni-Zadeh, Brice Guerpillon, Lydie Khatchatourian, Nadia Saidani, Jean-Philippe Talarmin, Marion Dollat, Nicolas Gambier, Marie-Aude Khuong, Yacine Tandjaouilambiotte, Marielle Buisson, Francois Xavier Catherine, Pascal Chavanet, Michel Duong, Clementine Esteve, Sophie Mahy, Lionel Piroth, Pascal Andreu, Francois Aptel, Pierre-Emmanuel Charles, Marie Labruyere, Sebastien Prin, Jean-Pierre Quenot, Jean-Baptiste Roudaut, Nicolas Aswad, Guillaume Beltramo, Amaury Berrier, Philippe Bonniaud, Charlotte Dignoire, Nicolas Favrolt, Marjolaine Georges, Claudio Rabec, Maximilien Spanjaard, Constance Guillaud, Georgeta Lascu Dubos, Jean-Daniel Lelievre, Matthieu Mahevas, Sebastien Gallien, Hanane Mehawej, Giovanna Melica, Marc Michel, Florence Runyo, Noemie Saada, William Vindrios, Veronique Delcey, Sandra Devatine, Aude Kopp, Victoria Manda, Anne-Lise Munier, Pierre Sellier, Arnaud Salmon-Rousseau, Emmanuel Faure, Florence Ader, Dulce Alfaiate, Bernard Allaouchiche, Agathe Becker, Nicolas Benech, Arthur Bert, Elodie Berton, Laurent Bitker, Julien Bohe, Evelyne Braun, Olivier Cannesson, Paul Chabert, Pierre Chauvelot, Christian Chidiac, René Chumbi Flores, Anne Conrad, Gilles Devouassoux, Tristan Ferry, Frederic Gormand, Agathe Granger, Pierre Grumet, Lucille Jay, Emilie Joffredo, Thomas Jullien, Lize Kiakouama, Melanie Levrad, Ibrantina Lucena e Silva, Mehdi Mezidi, Patrick Miailhes, Oriane Pelton, Thomas Perpoint, Thierry Petitjean, Francois Philit, Cecile Pouderoux, Jean-Christophe Richard, Gaelle Richard-Colmant, Sandrine Roux, Pascal Seve, Fabrice Thiolliere, Claire Triffault Fillit, Florent Valour, Olivia Vassal, Florent Wallet, Hodanne Yonis, Sylvie Abel, Bastien Bigeard, André Cabié, Ornella Cabras, Karine Guitteaud, Melanie Lehoux, Athena Marquise, Sandrine Pierre-François, Jean-Marie Turmel, Haffiane Abdelmagid, Alexis Hanisch, Flore Lacassin-Beller, Marion Mirabel, Isabel Roca Cerezo, Arnaud Sement, Charlotte Boulle, Jordan Lejeune, Vincent Le Moing, David Morquin, Nathalie Pansu, Lucas Perez, Mathieu Baldacini, Samuel Degoul, Anne-Florence Dureau, Carmen Ionescu, Khaldoun Kuteifan, Guylaine Labro, Joy Mootien, Pierre Oudeville, Luis Pinto, Antoine Poidevin, Yannick Rabouel, Laure Stiel, Guillaume Baronnet, Elisabeth Baux, Sybille Bevilacqua, Alice Corbel, François Goehringer, Eliette Jeanmaire, Antoine Kimmoun, Benjamin Lefevre, David Boutoille, Emmanuel Canet, Colin Deschamvres, Benjamin Gaborit, Charlotte Garret, Pauline Lamouche Wilquin, Jean-Baptiste Lascarrou, Paul Le Turnier, Anne Sophie Lecompte, Raphael Lecomte, Jeremie Lemarie, Maelle Martin, Arnaud Felix Miailhe, Gregoire Ottavy, Gwennaelle Querne, François Raffi, Jean Reignier, Amelie Seguin, Stijn Sruvay, Olivier Zambon, Fanny Lanternier, Cléa Melenotte, Claire Rouzaud, Alexandra Serris, Julia Beatini, Matthieu Buscot, David Chirio, Johan Courjon, Eric cua, Aurelien Degoutte, Elisa Demonchy, Jacques Durant, Sylvie Leroy, Charles-Hugo Marquette, Celine Michelangeli, Veronique Mondain, Bernard Prouvost-Keller, Pascal Pugliese, Karine Risso, Stephanie Bulyez, Aurele Buzancais, Aurelien Daurat, Romaric Larcher, Paul Loubet, Guillaume Louart, Laurent Muller, Nicolas Perin, Claire Roger, Guillaume Beraud, Melanie Catroux, France Cazenave-Roblot, Valentin Giraud, Gwenael Le Moal, Jean-Philippe Martellosio, Firouze Bani-Sadr, Messaline Bermejo, Joel Cousson, Antoine Goury, Maxime Hentzien, Gautier Julien, Bruno Mourvillier, Yohan Nguyen, Thibault Tromeur, Jean-Sebastien Allain, Marion Baldeyrou, François Benezit, Marie Dewitte, Fabrice Laine, Bruno Laviolle, Solene Patrat-Delon, Matthieu Revest, Pierre Tattevin, Hafid Ait-Oufella, Diane Bollens, Thibault Chiarabini, Patrick Ingiliz, Karine Lacombe, Benedicte Lefebvre, Jean-Luc Meynard, Nadia Valin, Elisabeth Botelho-Nevers, Sandrine Accassat, Celine Cazorla, Elodie De Magalhaes, Anne Fresard, Amandine Gagneux-Brunon, Marie-France Lutz, Jerome Morel, Flora Schein, Guillaume Thiery, Nathalie De Castro, Blandine Denis, Geoffroy Liegeon, Jean-Michel Molina, Emma Rubenstein, Mariagrazia Tateo, Jessie Cattelan, Raphael Clere-Jehl, Francois Danion, Yves Hansmann, Julie Helms, Christine Kummerlen, Nicolas Lefebvre, Sebastien Loewert, Hamid Merdji, Ferhat Meziani, Alexandra Monnier, Walid Oulehri, Hassene Rahmani, Yvon Ruch, Antoine Studer, Charles Ambroise Tacquard, Axel Ursenbach, Marwa Bachir, Ruxandra Calin, Julie Chas, Ludovic Lassel, Marine Nadal, Christia Palacios, Gilles Pialoux, Martin Siguier, Muriel Alvarez, Fabienne Calvas, Helene Catala, Alexa Debard, Pierre Delobel, Monique Galitzky, Camille Garnier, Gaspard Grouteau, Nicolas Guibert, Pauline Lansalot-Matras, Simon Lauret, Lucie Lelievre, Guillaume Martin Blondel, Julien Mazieres, Elise Noelsavina, Sarah Pellerin, Sandrine Pontier-Marchandise, Lydie Porte, Gregoire Prevot, Stella Rousset, Kamila Sedkaoui, Claire Thalamas, Frederic Bastides, Laetitia Bodet Contentin, Claudia Carvalho-Schneider, Francois Coustilleres, Pierre-Francois Dequin, Stephan Ehrmann, Thomas Flament, Denis Garot, Maeva Gourraud, Antoine Guillon, Sophie Jacquier, Charlotte Larrat, Annick Legras, Adrien Lemaignen, Marion Lacasse, Julie Mankikian, Emmanuelle Mercier, Lucile Rouault, Charlotte Salmon Gandonniere, Tiphaine Guy, Marie Gousseff, Emma D'Anglejan, Paraskevi Fragkou, Ioannis Grigoropoulos, Charalampos Moschopoulos, Sotirios Tsiodras, Georgios Tsioulos, Nikolaos Tziolos, Anastasia Kotanidou, Maria Theodorakopoulou, Edison Yajai, Carolina Akinosoglou, Vasiliki Dimakopoulou, Marcos Maragkos, Elena Polyzou, Argyrios Tzouvelekis, Imre Bakos, Eva Sandor, Istvan Varkonyi, Richard Armos, Szili Balazs, Takacs Istvan, Colm Bergin, Brian Kent, Colm Kerr, Liam Townsend, Myriam Alexandre, Nassera Aouali, Vic Arendt, Tania Bintener, Pierre Braquet, Esther Calvo Lasso de la Vega, Joelle Colling, Gaelle Damilot, Thomas Henin, Christian Michaux, Jean Reuter, Therese Staub, Lamia Skhiri, Christophe Werer, Ali Znati, Jan Erik Berdal, Olav Dalgard, Ole Kristian Fossum, Hedda Hoel Simen Schive, Ane-Kristine Fin, Aleksander-Rygh Holten, Synne Jenum, Maghild Eide Macpherson, Anne Ma Dyrhol Riise, Kristian Tonby, Sandra Braz, Joao Miguel Ferreira Ribeiro, José-Artur Paiva, Roberto Roncon-Albuquerque, Sandra de la Rosa Riestra, Zaira Raquel Palacios Baena, Patricia Perez Palacios, Jesus Rodriguez Bano
    Clinical Microbiology and Infection, 2026
  • Defective RNA Polymerase III sensing of mitochondrial DNA in pulmonary epithelial cells impairs type I IFN immunity to SARS-CoV-2
    Michelle Møhlenberg, Sofie Eg Jørgensen, Renée Marije van der Sluis, Thomas Zillinger, Daniëla Maria Hinke, Anne Kruse Hollensen, Anne Louise Hansen, , , , , , , , , , Pierre Hausfater, Guy Gorochov, Florence Tubach, Jade Ghosn, Cedric Laouenan, Merete Storgaard, Christian Kanstrup Holm, Helen Su, Rebeca Pérez de Diego, Aurora Pujol, Shen-Ying Zhang, Qian Zhang, Fernanda Sales Luiz Vianna, Laurent Abel, Aurélie Cobat, Jean-Laurent Casanova, Trine H. Mogensen
    Proceedings of the National Academy of Sciences of the United States of America, 2026
    The clinical spectrum of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection ranges from asymptomatic cases to critical COVID-19 pneumonia. To investigate the role of host genetics in susceptibility to critical COVID-19 and identify pathophysiological mechanisms and pathways, we analyzed whole-exome and whole-genome sequencing data from the COVID Human Genetic Effort. We identified 10 rare, monoallelic predicted loss-of-function variants in 18 patients in POLR3A and POLR3C encoding two subunits of RNA polymerase III (POL III), a nuclear multisubunit enzyme, which has been implicated in cytosolic DNA sensing. These variants were deleterious for expression of full-length POLR3A and POLR3C proteins. We demonstrate that human pulmonary A549-hACE2 cells with reduced POLR3A or POLR3C expression exhibit impaired type I IFN responses to transfected mitochondrial DNA (mtDNA) or SARS-CoV-2 infection, together with increased viral replication. Mechanistically, we show that SARS-CoV-2 induces cellular mtDNA release via oligomerization of the mitochondrial voltage-dependent anion channel under virus-induced oxidative stress, enabling POL III–mtDNA interaction. These findings establish POL III as a sensor of endogenous mtDNA released during viral infection and indicate that autosomal dominant POL III haploinsufficiency may predispose individuals to critical COVID-19.
  • Real-world emergence of nirsevimab resistance in breakthrough infections with respiratory syncytial virus-B: a multicentre observational study in France
    Slim Fourati, Alawiya Reslan, Jérôme Bourret, Jean-Sébastien Casalegno, Yannis Rahou, Laurent Softic, Lionel Chollet, Pauline Trémeaux, Berthe-Marie Imbert-Marcille, Sylvie Pillet, Nicolas Veyrenche, Agathe Boudet, Luc Deroche, Sonia Burrel, Lina Mouna, Theophile Cocherie, Aurélie Schnuriger, Charlotte Pronier, Lynda Handala, Véronique Brodard, Floriane Gallais, Sylvie Larrat, Alexandre Regueme, Nefert Candace Dossou, Amandine Henry, Elyanne Gault, Cédric Hartard, Ségolène Brichler, Alice Moisan, Véronique Avettand-Fenoel, Caroline Lefeuvre, Ilka Engelmann, Sandrine Castelain, Audrey Mirand, Maud Salmona, Marie-Christine Jaffar-Bandjee, Mohamed Ader, Sarah Seng, Pierre Cappy, Christophe Rodriguez, Arnaud Ly, Georges Dos Santos, Olivier Schwartz, Chloé Petiot, Delphine Planas, Samar Berreira Ibraim, Kévin Da Silva, Amélie Recoing, Jean-Michel Pawlotsky, Frédéric Lemoine, Etienne Audureau, Marie-Anne Rameix-Welti, Naël Zemali, Sonia Burrel, Pantxika Bellecave, Alice Moisan, Zakasoa-Mbololona Zavaoarisaina, Romain Legros, Boris Derman, Vincent Pargny, Hortense Petat, Jean-Christophe Plantier, Véronique Avettand-Fenoel, Salim Ferrani, Jérome Guinard, Clémence Guillaume, Gilbert Mchantaf, Victoria Marie, Laurent Bret, Fabien Lesne, Anthony de Oliveira, Alexandre Regueme, Kazali Alidjinou, Lionel Chollet, Vincent Gardan, Ségolène Brichler, Loic de Pontual, Camille Aupiais, Stéphane Marot, Aurélie Schnuriger, Marine Perrier, Pierre Jatteau, Djeneba Fofana, Théophile Cocherie, Elisa Teyssou, Cathia Soulié, Vincent Calvez, Sylvie Larrat, Anne Faisant, Guillaume Mortamet, Caroline Tournegros, Mohamed Habib, Sylvie Pillet, Aymeric Cantais, Franck Zekre, Thomas Bourlet, Oulfa Boussetta-Charfi, Sara Chenafi-Adham, Eva Gleizes, Cédric Hartard, Caroline Lefeuvre, Elise Bouthry, Lina Mouna, Fairly Warnakulasuriya, Quentin Le Hingrat, Marie-Christine Jaffar-Bandjee, Diana Heaugwane, Benjamin Azemar, Nicolas Mnemosyme, Laurent Souply, Catherine François, Sandrine Castelain, Cinthia Rames, Arnaud Bécourt, Ilka Engelmann, Eric Jeziorski, Vincent Foulongne, Lynda Handala, Catherine Gaudy-Graffin, Agathe Crémadés, Amandine Henry, Alessandra Pennisi, Maud Salmona, Jérôme Le Goff, Audrey Gabassi, Marie-Laure Néré, Marine Minier, Audrey Baron, Stéphane Bonacorsi, Naim Ouldali, Abdeljalil Senhaji Rachik, Marie-Anne Rameix-Welti, Alawyia Reslan, Yannis Rahou, Banujaa Jeyarajah, Anne Huard de Verneuil, Jérome Bourret, Frédéric Lemoine, Kévin Da Silva, Samar Berreira Ibraim, Vincent Enouf, Danielle Perez-Bercoff, Lucy Mosscrop, Etienne Simon-Loriere, Nefert Candace Dossou, Astrid Vabret, Slim Fourati, Christophe Rodriguez, Jean-Michel Pawlotsky, Pierre Cappy, Alexandre Soulier, Mohamed Ader, Sarah Seng, Arnaud Ly, Amandine Caillault, Pierre-André Natella, Etienne Audureau, Georges Dos Santos, Laurence Fagour, Anne-Julie Schapira, Olivier Flechelles, Luc Deroche, Nicolas Lévêque, Claire Morton Fauche, Sarah Borel, Erwan Ripley, Juliette Aubin, Berthe-Marie Imbert, Louise Castain, Audreay Rodallec, Justine Sourice, Christele Gras-Le Guen, Anne Chauvire-Drouard, Elyanne Gault, Frédérique Moreau, Claire Deback, Floriane Gallais, Morgane Solis, Valentin Stephan, Léa Pilorgé, Sophie Vallet, Léa Gaitan, Sylvie Rogez, Audrey Mirand, Cecile Henquell, Charlotte Pronier, Claire Grolhier, Vincent Thibault, Pauline Trémeaux, Isabelle Claudet, Mélanie Pucelle, Laetitia Staes, Camille Vellas, Sofia Demmou, Romain Carcenac, Nicolas Veyrenche, Jean-sébastien Casalegno, Alexandre Gaymard, Jose Kombou, Antonin Bal, Stanislas Ogoudjobi, Agathe Boudet, Amélie Recoing
    Lancet Microbe, 2026
    BACKGROUND: Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in infants. Nirsevimab, a long-acting monoclonal antibody targeting a conserved epitope on the prefusion F protein (site Φ), has shown high efficacy in clinical trials and early real-world studies. Although widespread resistance has not been reported, concerns remain about the emergence of escape variants, particularly among RSV-B viruses. During the 2024-25 RSV season in France, RSV-B predominated, providing a unique opportunity to examine breakthrough infections with RSV-B and resistance at a large scale. The study aimed to characterise RSV escape from nirsevimab using genotypic and phenotypic methods. METHODS: This POLYRES-2 project was a multicentre, national, observational study conducted in hospital settings (inpatients and outpatients) across France during the 2024-25 RSV season. We included infants aged 1 year or under with a RT-PCR-confirmed RSV infection in routine care, regardless of whether they had received nirsevimab. Infants were identified through hospital virology laboratory databases. Each participating centre was requested to include a balanced number of nirsevimab-exposed and non-exposed infected infants throughout the study period. Clinical data were retrieved from electronic medical records. We compared RSV susceptibility to nirsevimab in infants who received nirsevimab with that in nirsevimab-naive infants. Respiratory samples were sequenced for full-length RSV genomes. To ensure reliability, phylogenetic and mutational analyses were restricted to high-quality sequences with greater than or equal to 90% genome coverage and complete reads across the nirsevimab-binding site. Clinical RSV isolates were tested for neutralisation by nirsevimab. We analysed F candidate substitutions using a fusion inhibition assay. The primary outcomes were presence of RASs in the RSV F protein (site Φ) and phenotypic resistance to nirsevimab. FINDINGS: Among 1023 RSV-infected infants, 858 (83·9%) had full-length RSV genome sequences: 419 (48·8%) from nirsevimab-treated breakthrough infections (212 [50·6%] RSV-A, 207 [49·4%] RSV-B) and 439 (51·2%) from nirsevimab-naive infants (192 [43·7%] RSV-A, 247 [56·3%] RSV-B). RASs were identified in two of 195 RSV-A breakthrough infections (1·0%) and in 23 of 184 RSV-B breakthrough infections (12·5%). In RSV-A, the only RAS was F:K209E, conferring intermediate resistance. In RSV-B, resistance was more frequent and diverse than in RSV-A: 12 of 23 (52.2%) resistant viruses carried a substitution at residue 208 (F:N208D, F:N208I, F:N208K, F:N208S, or F:N208Y). Additional novel substitutions, including F:I64V/F:K65E, F:K68I, F:L204S, and F:P205S, also mediated resistance. Notably, a resistant RSV-B variant (F:N208S) was detected almost 1 year after prophylaxis. No resistant RSV was detected in nirsevimab-naive infants. INTERPRETATION: Resistance to nirsevimab in RSV-B can emerge in real-world settings, affecting around 12% of breakthrough infections and showing greater diversity than previously recognised, although the clinical impact remains constrained by available evidence. Detection of resistant variants long after prophylaxis highlights the need for extended genomic surveillance. Integration of clinical and virological data will be essential to sustain the long-term effectiveness of RSV monoclonal antibody programmes. FUNDING: This study was supported by a grant from the Agence Nationale de Recherche sur le Sida et les hépatites virales - Maladies Infectieuses Emergentes and the French Ministry of Health and Prevention.
  • Urban environment and RSV: a retrospective observational study of neighbourhood factors associated with the risk of severe disease in the infant population of a metropolitan area, Lyon, France
    Kaisa Jaakkola, Florent Renard, Alvaro Roy, Mehdi Benchaib, Jessica Metcalf, Rachel Baker, Bruno Simon, Gabriel Vecchi, Dominique Ploin, Yves Gillet, Etienne Javouhey, Bruno Lina, Bryan T. Grenfell, Jean-Sebastien Casalegno, , Aymeric Cantais, Elsa Masson, Emilie Bard, Martine Valette, Remi Fanget, Sandrine Couray Targe, Anne-Florence Myar-Dury, Muriel Doret-Dion, Mona Massoud, Gregory Queromes, Philippe Vanhems, Olivier Claris, Marine Butin, Sylvie Pillet, Florence Ader, Sylvie Bin, Alexandre Gaymard, Florence Morfin
    BMC Public Health, 2025
    Severe acute respiratory infections (SARI) caused by a human respiratory syncytial virus (RSV) are a leading cause of hospitalisation among infants. We aimed to estimate the incidence of RSV SARI across neighbourhoods in the Lyon metropolitan area and to assess how urban environmental factors at the metropolitan scale are associated with spatial variation in incidence. Laboratory-confirmed cases of RSV SARI (< 2 years of age) were extracted from the university hospitals of Lyon laboratory database 2015–2023. We calculated and mapped the incidence to assess spatial variation. Remote sensing data were used to derive spectral indices characterising the metropolitan area and to model temperature and air humidity at this scale. Temporal and spatial regression models were fitted using variables selected based on prior knowledge and data availability. Cumulative incidence varied significantly across neighbourhoods (0 to 1166 cases per 100,000 people at risk; p-value < 0.001). The best spatial multivariate model (r2 = 0.39, Akaike information criterion (AIC) = 6103), explained a substantial portion of this variation, and included neighbourhood median income that was negatively associated with incidence; and neighbourhood winter temperature as well as particulate matter < 10 µm pollution, both positively associated with incidence. Additionally, urban index (UI) and normalised difference moisture index (NDMI) demonstrated strong (p-value < 0.001) univariate associations (UI: r2 = 0.23, AIC = 6216; NDMI: r2 = 0.21, AIC = 6229), accounting for a significant portion of the incidence variation. Substantial neighbourhood-level differences in RSV SARI incidence exist in a large European metropolis. These differences are associated with the urban environment such as particulate pollution. The use of spectral indices shows promise in identifying vulnerable populations within cities to guide public health measures and to integrate public health and urban planning.
  • sST2 is a key outcome biomarker in COVID-19: insights from discovery randomized trial
    David M. Smadja, Clément R. Massonnaud, Aurélien Philippe, Mickael Rosa, Sophie Luneau, Antoine Rauch, Nathan Peiffer-Smadja, Amandine Gagneux-Brunon, Julien Poissy, Maxime Gruest, Alexandre Ung, Valérie Pourcher, François Raffi, Lionel Piroth, Kévin Bouiller, Hélène Esperou, Christelle Delmas, Drifa Belhadi, Alpha Diallo, Juliette Saillard, Aline Dechanet, Noémie Mercier, Axelle Dupont, François-Xavier Lescure, François Goehringer, Stéphane Jaureguiberry, François Danion, Violaine Tolsma, André Cabie, Johan Courjon, Sylvie Leroy, Joy Mootien, Bruno Mourvillier, Sébastien Gallien, Jean-Philippe Lanoix, Elisabeth Botelho-nevers, Florent Wallet, Jean-Christophe Richard, Jean Reuter, Alexandre Gaymard, Richard Greil, Guillaume Martin-Blondel, Claire Andrejak, Yazdan Yazdanpanah, Charles Burdet, Jean-Luc Diehl, Maya Hites, Florence Ader, Sophie Susen, France Mentré, Annabelle Dupont, , Sandrine Couffin-Cadièrgues, Hélène Esperou, Bernd Lamprecht, Michael Joannidis, Alexander Egle, Richard Greil, Antoine Altdorfer, Vincent Fraipont, Leila Belkhir, Maya Hites, Gil Verschelden, Violaine Tolsma, David Bougon, Agathe Delbove, Marie Gousseff, Nadia Saidani, Guilhem Wattecamps, Félix Djossou, Loïc Epelboin, Jean-Philippe Lanoix, Pierre-Alexandre Roger, Claire Andrejak, Yoann Zerbib, Kevin Bouiller, Catherine Chirouze, Jean-Christophe Navellou, Alexandre Boyer, Charles Cazanave, Alexandre Duvignaud, Didier Gruson, Denis Malvy, Henry Lessire, Martin Martinot, Pascal Andreu, Mathieu Blot, Lionel Piroth, Jean Pierre Quenot, Olivier Epaulard, Nicolas Terzi, Karine Faure, Emmanuel Faure, Julien Poissy, Saad Nseir, Florence Ader, Laurent Argaud, Tristan Ferry, Thomas Perpoint, Vincent Piriou, Jean-Christophe Richard, Julien Textoris, Florent Valour, Florent Wallet, André Cabié, Jean-Marie Turmel, Cyrille Chabartier, Rostane Gaci, Céline Robert, Alain Makinson, Vincent Le Moing, Kada Klouche, Olivier Hinschberger, Joy Mootien, Sébastien Gibot, François Goehringer, Antoine Kimmoun, Benjamin Lefevre, David Boutoille, Emmanuel Canet, Benjamin Gaborit, Paul Le Turnier, François Raffi, Jean Reignier, Johan Courjon, Jean Dellamonica, Sylvie Leroy, Charles-Hugo Marquette, Paul Loubet, Claire Roger, Albert Sotto, Cédric Bruel, Benoît Pilmis, Guillaume Geri, Elisabeth Rouveix-Nordon, Olivier Bouchaud, Samy Figueiredo, Stéphane Jaureguiberry, Xavier Monnet, Lila Bouadma, François-Xavier Lescure, Nathan Peiffer-Smadja, Jean-François Timsit, Yazdan Yazdanpanah, Solen Kerneis, Marie Lachâtre, Odile Launay, Jean-Paul Mira, Julien Mayaux, Valérie Pourcher, Jérôme Aboab, Flora Crockett, Naomi Sayre, Clément Dubost, Cécile Ficko, David Lebeaux, Sébastien Gallien, Armand Mekontso-Dessap, Jérôme Le Pavec, Francois Stefan, Hafid Ait-Oufella, Karine Lacombe, Jean-Michel Molina, Murielle Fartoukh, Gilles Pialoux, Firouzé Bani-Sadr, Bruno Mourvillier, François Benezit, Fabrice Laine, Bruno Laviolle, Yves Le Tulzo, Matthieu Revest, Elisabeth Botelho-Nevers, Amandine Gagneux-Brunon, Guillaume Thiery, François Danion, Yves Hansmann, Ferhat Meziani, Walid Oulehri, Charles Tacquard, Fanny Bounes-Vardon, Guillaume Martin-Blondel, Marlène Murris-Espin, Béatrice Riu-Poulenc, Vanessa Jeanmichel, Eric Senneville, Louis Bernard, Denis Garot, Jean Reuter, Thérèse Staub, Marc Berna, Sandra Braz, Joao Miguel Ferreira Ribeiro, José-Artur Paiva, Roberto Roncon-Albuquerque, Benjamin Leveau
    Scientific Reports, 2025
    We investigated whether baseline levels of biomarkers related to endotheliopathy, thromboinflammation, and fibrosis were associated with clinical outcomes in hospitalized COVID-19 patients. We analyzed the associations between baseline levels of 21 biomarkers and time to hospital discharge and change in NEWS-2 score in patients from DisCoVeRy trial. We fitted multivariate models adjusted for baseline ISARIC 4C score, disease severity, D-dimer values, and treatment regimen. Between March 22 and June 29, 2020, 603 participants were randomized; 454 had a sample collected at baseline and analyzed. The backward selection of multivariate models showed that higher baseline levels of soluble suppressor of tumorigenicity 2 (sST2) and nucleosomes were statistically associated with a lower chance of hospital discharge before day 29 (sST2: aHR 0.24, 95% CI [0.15–0.38], p < 10 −9 ; nucleosomes: aHR 0.62, 95% CI [0.48–0.81], p < 10 −3 ). Likewise, higher levels of baseline sST2 were statistically associated with lower changes in the NEWS-2 score between baseline and day 15 (adjusted beta 4.47, 95% CI [2.65–6.28], p < 10 −5 ). Moreover, we evaluated sST2 involvement in a confirmation cohort (SARCODO study, 103 patients) and found that elevated baseline sST2 levels were significantly associated with lower rates of hospital discharge before day 29 and a higher model performance (AUC at day 29 of 92%) compared to models without sST2. sST2 emerged as an independent predictor of clinical outcomes in two large cohort of hospitalized COVID-19 patients, warranting further investigation to elucidate its role in disease progression and potential as a therapeutic target.
  • Rapid-sequence clinical research before and during a pandemic: Lessons learned and the way forward
    Florence Ader, Éloïse Aubret, Nathalie Bergaud, Maude Bouscambert-Duchamp, Sophie Circosta, Sandrine Couffin-Cadiergues, François Danion, Christelle Delmas, Alpha Diallo, Emmanuel Faure, Claire Fougerou-Leurent, Alexandre Gaymard, Karine Lacombe, Soizic Le Mestre, Clara Locher, Auriane Merelle, Nathan Peiffer-Smadja, Isabelle Pellegrin, Ventzislava Petrov-Sanchez, Linda Wittkop
    Infectious Diseases Now, 2025
    In the aftermath of the COVID-19 pandemic, the structuring of a nationwide research network for preparation and response to emerging infectious diseases (EID) with epidemic or pandemic potential has become increasingly essential. A nationwide EID operational research network (OPEN-ReMIE),is funded for five years through the France 2030 program and run by the French national research agency (ANR). Its primary missions are to accelerate hospital-based clinical research under epidemic or pandemic conditions with academic or industrial sponsors, and to pursue this effort in international research networks. OPEN-ReMIE governance is geared to steering this network and to guaranteeing its operability in inter- as well as crisis modes. It will be the point of entry for key international trial platforms, academic and private sponsors, regulatory agencies, associations of citizens and patients, and think tanks committed to promoting scientific integrity. OPEN-ReMIE encompasses six work packages: (i) regulatory affairs, sponsoring, fast-track procedures and contracts; (ii) clinical site network management; (iii) methodology and management centers to provide methodological expertise (generic master protocols, sets of core and extended variable catalogs, electronic case reports form templates, data management and interoperability, monitoring…); (iv) laboratory and biological resource center management; (v) drug supply and pharmacovigilance supervisory board; (vi) training programs and communication plans for various stakeholders: research teams, healthcare professionals, students, associations of citizens and patients and, increasingly, civil society actors. All in all, OPEN-ReMIE is a nationwide "preparedness task force" embedded in a large-scale European consortium for EID clinical research and working with other international EID clinical research platforms.
  • Community and Hospital-Based Laboratory Surveillance for Influenza, Respiratory Syncytial Virus, and SARS-CoV-2 During the 2023–2024 Season, Lyon, France
    Cécile Chauvel, Jean‐Sébastien Casalegno, Benoit Visseaux, Vincent Vieillefond, Stéphanie Haim‐Boukozba, Vincent Enouf, Emmanuel Chanard, Margaux Fabre, Marie‐Anne Rameix‐Welti, Antoine Oblette, Jean‐Marc Giannoli, Juliette Paireau, Laurence Josset, Bruno Lina, Alexandre Gaymard, Simon Cauchemez, Florence Morfin, Marta C. Nunes, Antonin Bal
    Journal of Medical Virology, 2025
    Influenza, respiratory syncytial virus (RSV) and SARS‐CoV‐2 are among the main respiratory viruses circulating in the population, with a significant burden on public health. While individuals at higher risk are more likely to develop severe symptoms leading to hospitalization, viral circulation in the community remains less extensively monitored. This study compared viral circulation between RELAB, a recently established community‐based laboratory surveillance network (n = 22 843 tested patients) and hospital surveillance at the Hospices Civils de Lyon, France (n = 23 046 tested patients), for the season 2023–2024. For influenza and SARS‐CoV‐2, similar trends were observed in at‐risk populations (children under 5 years and adults over 65 years) in both settings. Circulation of these two viruses was first detected in the community and insights from the young adult population (19–64 years) were only captured in the community network. Circulation of RSV was more intense in terms of number of cases and started in the pediatric population, and consequently was more represented in the hospital setting. In conclusion, this study highlighted the complementarity between community and hospital surveillance, as different populations and periods of viral circulation were observed.
  • Clinical Characterization and Outcomes of Human Clade IIb Mpox Virus Disease: A European Multicenter Mpox Observational Cohort Study (MOSAIC)
    Elise Pesonel, Cédric Laouénan, Laetitia Guiraud, Josephine Bourner, Isabelle Hoffmann, Diana Molino, Coralie Tardivon, Delphine Bachelet, France Mentré, Alain Amstutz, Laura Merson, Amanda Rojek, Minerva Cervantes Gonzalez, Andrea Antinori, Antonella Castagna, Silvia Nozza, Valérie Pourcher, Agnès Libois, Jake Dunning, Evelina Tacconelli, Maya Hites, Fernando De La Calle Prieto, Peter Horby, Yazdan Yazdanpanah, Alexandra Calmy, François-Xavier Lescure, Piero Olliaro, , Maya Hites, Leïla Belkhir, Marie-Angélique De Scheerder, Jean-Christophe Goffard, Agnès Libois, Zineb Khalil, Catherine Orban, Lucie Seyler, Clotilde Visée, Florence Ader, Antoine Bachelard, Yasmine Bouaraba, Jean-Marc Chapplain, Hugues Cordel, François Danion, Aurélien Dinh, Nikita Dobremel, Manuel Etienne, Pierre Frange, Karine Faure, François Goehringer, Karine Lacombe, Xavier Lescure, Rodolphe Manaquin, Guillaume Martin-Blondel, Jean-Michel Mansuy, Giovanny Gombert, Duc Nguyen, Romain Palich, Gilles Pialoux, Aoife Cotter, Virginie Gautier, Evelina Tacconelli, Oriana Awwad, Andrea Antinori, Antonella Castagna, Silvia Nozza, Angelo Roberto Raccagni, Elena Bruzzesi, Antonio Cascio, Annamaria Cattelan, Maddalena Cordioli, Giulia De Luca, Lorenza Lambertenghi, Giulia Marchetti, Valentina Mazzotta, Emanuele Nicastri, Vincenzo Scaglione, Carlo Tascini, Jorge Machado, Lurdes Santos, Wong Chen Seong, Travis Ren Teen Chia, Wilnard Yeong Tze Tan, Fernando De La Calle Prieto, Vicente Estrada, Miguel Nicolás Navarrete Lorite, Alfredo Soler Carracedo, Maria Velasco Arribas, Dominique Braun, Alexandra Calmy, Matthias Cavassini, Lorenzo Ciullini, Stéphane Emonet, Chiara Fedeli, Yvan Gosmain, Laetitia Guiraud, Benjamin Hampel, Olivier Segeral, Cornelia Staehelin, Marcel Stöckle, Alejandro Arenas-Pinto, Mike Beadsworth, Margherita Bracchi, Joby Cole, Jake Dunning, Michael Marks, Brendan Payne, Malcolm G Semple, Claire Waddington, Chris Ward, Alain Amstutz, Dominique Costagliola, Jérémie Guedj, Inge Christoffer Olsen, Diane Descamps, Christophe Batejat, Jessica Vanhomwegen, Maude Bouscambert-Duchamp, Julio Garcia Rodriguez, Alexandre Gaymard, Andreas Lind, Fabrizio Maggi, Hervé Raoul, Jeroen Van Kampen, Sabine Yerly, Nicolas Yin, Léo Chenard, Ismaila Deme, Alpha Diallo, Séverine Gibowski, Sabrina Kali, Guillaume Le Meut, Sophie Letrou, Claire Madelaine, Hervé Raoul, Ventzislava Petrov Sanchez
    Clinical Infectious Diseases, 2025
    Background The global mpox outbreak that started in May 2022 was caused by a novel clade IIb variant of the mpox virus (Orthopoxvirus monkeypox, MPXV). It differed from the traditional Western and Central Africa disease in transmission patterns and clinical presentation. Methods To address the need for detailed clinical and virologic data, we conducted an observational cohort study (MOSAIC) during May 2022–July 2023 in individuals with confirmed MPXV infection enrolled in 6 European countries. Case management decisions were left to the attending physician. Participants were monitored for up to 6 months for clinical signs/symptoms and clinical and virologic outcomes through hospital visits, phone interviews, and self-administered questionnaires. Outcomes included time to lesion resolution, clinical status, and virus clearance. Results The 518 participants not receiving any specific treatment (“untreated”) were diagnosed a median 5 days from symptom onset; 90% were managed as outpatients. Lesions were mostly cutaneous (88%) and perigenital (74%). By day 14 from the first polymerase chain reaction (PCR)–positive sample, 39% had resolved lesions. Time to 95% unculturable virus was longest in cutaneous lesions (52 days). A putative systemic antiviral was available for 57 participants, 44% as inpatients; 34% and 58% had resolved lesions by day 14 from the first PCR-positive sample and from treatment start, respectively. Time to 95% unculturable virus was 60 days in skin and oropharynx. No death or recrudescence occurred by day 180. Conclusions MOSAIC provides comprehensive insights into the clinical and virologic characteristics of mpox caused by the clade IIb variant. The study forms the basis of clinical characterization for ongoing mpox outbreaks.
  • Performance of Subgenomic RT-PCR for Predicting SARS-CoV-2 Infectivity Compared to Genomic RT-PCR and Culture Isolation
    Célia Sentis, Delphine Parraud, Geneviève Billaud, Martine Valette, Maude Bouscambert‐Duchamp, Bruno Lina, Florence Morfin, Alexandre Gaymard
    Journal of Medical Virology, 2025
    SARS‐CoV‐2 clinical samples can be detected as positive for a long period of time using real‐time RT‐PCR, even when patients are no longer infectious. Viral culture is the gold standard for assessing a patient's infectivity, but it is a time‐consuming technique and lacks sensitivity. SARS‐CoV‐2 subgenomic RNA (sgRNA) detection has been used as a proxy for assessing the infectivity but only a limited number of studies have described its use in vitro and in clinical samples. This study aimed to evaluate the correlation between results from viral culture, genomic RT‐PCR (gRT‐PCR), and subgenomic RT‐PCR (sgRT‐PCR) during in vitro infection and in clinical samples. In vitro viral replication kinetics showed that both genomic RNA (gRNA) and subgenomic RNA (sgRNA) levels remained stable up to 21 days in the absence of replication‐competent virus. Using clinical samples, sgRNA was detected in 87.5% of culture‐positive samples, demonstrating better performances than gRT‐PCR (Positive predictive value (PPV) 93.3% and Negative predictive value (NPV) of 87.5%) and an almost perfect agreement with culture results (Cohen κ = 0.81 [95% CI: 0.66–0.95]). These findings suggest that testing for sgRNA and/or using a gRNA Ct cut‐off of 21.2 could be used as a proxy to determine the presence of SARS‐CoV‐2 replication‐competent virus.
  • Performance of whole genome sequencing for respiratory syncytial virus: insights from the first external quality assessment, France, 2024
    Alice Moisan, Hadrien Regue, Yannis Rahou, Alexandre Gaymard, Antoine Oblette, Léa Avon, Nathalie Bergaud, Richard Chalvignac, Quentin Le Hingrat, Sonia Burrel, Aude Jary, Philippe Colson, Pierre Cappy, Luc Deroche, Véronique Brodard, Charlotte Pronier, Elodie Alessandri-Gradt, Maud Salmona, Lionel Chollet, Pauline Trémeaux, Lynda Handala, Slim Fourati, Bruno Lina, Jean-Sébastien Casalegno, Nadhira Houhou, Romane Guilbaud, Thibault Saint-Joannis, Naël Zemali, Pantxika Bellecave, Lucie Mazarguil, Valentine Lesourd-Aubert, Stéphane Marot, Valentin Leducq, Théophile Cocherie, Antoine Fauchois, Vincent Calvez, Anne-Geneviève Marcelin, Bernard La Scola, Céline Boschi, Sarah Seng, Arnaud Ly, Hélène Moret, Mme Magda Curci, Mme Marion Couteau, Claire Grolhier, Vincent Thibault, Mohamed Sassi, Chloé Dubus, Marie Leoz, Fanny Lermechain, Jean-Christophe Plantier, Fabienne Tombette, Marie-Laure Nere, Audrey Gabassi, Abdeljalil Senhaji Rachik, Sarah Mafi, Jérôme Le Goff, Cécile Poggi, Anne Lise Toyer, Marie Domine, Vincent Gardan, Romain Carcenac, Sofia Demmou, Justine Latour, Camille Vellas, Thibault Guinoiseau, Yoan Laforgue, Sophie Trouillet Assant, Quentin Semanas, Gregory Destras, Jerome Bourret, Samar Berreira Ibraim, Emilie Yab, Emma Bezot, Florian Prejean, Marie-Anne Rameix-Welti, Laurence Josset, Antonin Bal
    Clinical Microbiology and Infection, 2025
  • Advancing respiratory virus diagnostics: integrating the nasal IFN-I score for improved viral detection
    Marine Mommert-Tripon, Delphine Parraud, Cloé Grosbois, Alexandre Gaymard, Valérie Cheynet, Bruno Lina, Guy Oriol, Frédéric Laurent, Caroline Dupré, Quentin Semanas, Antonin Bal, Laurence Generenaz, Sylvie Pons, Karen Brengel-Pesce, Audrey Guichard, William Mouton, Florence Morfin, Aurore Fleurie, Sophie Trouillet-Assant
    Ebiomedicine, 2024
  • Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 (Genome Medicine, (2023), 15, 1, (22), 10.1186/s13073-023-01173-8)
    Daniela Matuozzo, Estelle Talouarn, Astrid Marchal, Peng Zhang, Jeremy Manry, Yoann Seeleuthner, Yu Zhang, Alexandre Bolze, Matthieu Chaldebas, Baptiste Milisavljevic, Adrian Gervais, Paul Bastard, Takaki Asano, Lucy Bizien, Federica Barzaghi, Hassan Abolhassani, Ahmad Abou Tayoun, Alessandro Aiuti, Ilad Alavi Darazam, Luis M. Allende, Rebeca Alonso-Arias, Andrés Augusto Arias, Gokhan Aytekin, Peter Bergman, Simone Bondesan, Yenan T. Bryceson, Ingrid G. Bustos, Oscar Cabrera-Marante, Sheila Carcel, Paola Carrera, Giorgio Casari, Khalil Chaïbi, Roger Colobran, Antonio Condino-Neto, Laura E. Covill, Ottavia M. Delmonte, Loubna El Zein, Carlos Flores, Peter K. 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  • Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms
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Moharam, Sabriya Abdalasalam, Alaa Abdalfattah Abdalhadi, Naana Reyam Abdalla, Walaa Abdalla, Almthani Hamza Abdalrheem, Ashraf Abdalsalam, Saedah Abdeewi, Esraa Hassan Abdelgaum, Mohamed Abdelhalim, Mohammed Abdelkabir, Israa Abdelrahman, Sheryl Ann Abdukahil, Lamees Adil Abdulbaqi, Salaheddin Abdulhamid, Widyan Abdulhamid, Nurul Najmee Abdulkadir, Eman Abdulwahed, Rawad Abdunabi, Ryuzo Abe, Laurent Abel, Ahmed Mohammed Abodina, Amal Abrous, Lara Absil, Kamal Abu Jabal, Nashat Abu Salah, Abdurraouf Abusalama, Tareg Abdallah Abuzaid, Subhash Acharya, Andrew Acker, Elisabeth Adam, Safia Adem, Manuella Ademnou, Francisca Adewhajah, Diana Adrião, Anthony Afum-Adjei Awuah, Melvin Agbogbatey, Saleh Al Ageel, Aya Mustafa Ahmed, Musaab Mohammed Ahmed, Shakeel Ahmed, Zainab Ahmed Alaraji, Abdulrahman Ahmed Elhefnawy Enan, Reham Abdelhamid Ahmed Khalil, Ali Mostafa Ahmed Mohamed Abdelaziz, Kate Ainscough, Eka Airlangga, Tharwat Aisa, Ali Aisha, Bugila Aisha, Ali Ait Hssain, Younes Ait Tamlihat, Takako Akimoto, Ernita Akmal, Chika Akwani, Eman Al Qasim, Ahmed Alajeeli, Ahmed Alali, Razi Alalqam, Aliya Mohammed Alameen, Mohammed Al-Aquily, Zinah A. Alaraji, Khalid Albakry, Safa Albatni, Angela Alberti, Osama Aldabbourosama, Tala Al-dabbous, Amer Aldhalia, Abdulkarim Aldoukali, Senthilkumar Alegesan, Marta Alessi, Beatrice Alex, Kévin Alexandre, Abdulrahman Al-Fares, Asil Alflite, Huda Alfoudri, Qamrah Alhadad, Hoda Salem Alhaddad, Maali Khalid Mohamed Abdalla Alhasan, Ahmad Nabil Alhouri, Hasan Alhouri, Adam Ali, Imran Ali, Maha TagElser Mohammed Ali, Syed Ali Abbas, Yomna Ali Abdelghafar, Naseem Ali Sheikh, Kazali Enagnon Alidjnou, Mahmoud Aljadi, Sarah Aljamal, Mohammed Alkahlout, Akram Alkaseek, Qabas Alkhafajee, Clotilde Allavena, Nathalie Allou, Lana Almasri, Abdulrahman Almjersah, Raja Ahmed Alqandouz, Walaa Alrfaea, Moayad Alrifaee, Rawan Alsaadi, Yousef Al-Saba'a, Entisar Alshareea, Eslam Alshenawy, Aneela Altaf, João Melo Alves, João Alves, Rita Alves, Joana Alves Cabrita, Maria Amaral, Amro Essam Amer, Nur Amira, Amos Amoako Adusei, John Amuasi, Roberto Andini, Claire Andrejak, Andrea Angheben, François Angoulvant, Sophia Ankrah, Séverine Ansart, Sivanesen Anthonidass, Massimo Antonelli, Carlos Alexandre Antunes de Brito, Ardiyan Apriyana, Yaseen Arabi, Irene Aragao, Francisco Arancibia, Carolline Araujo, Antonio Arcadipane, Patrick Archambault, Lukas Arenz, Jean-Benoît Arlet, Christel Arnold-Day, Lovkesh Arora, Rakesh Arora, Elise Artaud-Macari, Diptesh Aryal, Angel Asensio, Elizabeth A. Ashley, Muhammad Ashraf, Muhammad Sheharyar Ashraf, Abir Ben Ashur, Franklin Asiedu-Bekoe, Namra Asif, Mohammad Asim, Grace Assi, Jean Baptiste Assie, Amirul Asyraf, Fouda Atangana, Ahmed Atia, Minahel Atif, Asia Atif Abdelrhman Abdallahrs, Anika Atique, Moad Atlowly, AM Udara Lakshan Attanyake, Johann Auchabie, Hugues Aumaitre, Adrien Auvet, Abdelmalek Awad Ali Mohammed, Eyvind W. Axelsen, Ared Ayad, Ahmed Ayman Hassan Helmi, Laurène Azemar, Mohammed Azizeldin, Cecile Azoulay, Hakeem Babatunde, Benjamin Bach, Delphine Bachelet, Claudine Badr, Roar Bævre-Jensen, Nadia Baig, John Kenneth Baillie, J Kevin Baird, Erica Bak, Agamemnon Bakakos, Nazreen Abu Bakar, Hibah Bileid Bakeer, Ashraf Bakri, Andriy Bal, Mohanaprasanth Balakrishnan, Irene Bandoh, Firouzé Bani-Sadr, Renata Barbalho, Nicholas Yuri Barbosa, Wendy S. Barclay, Saef Umar Barnett, Michaela Barnikel, Helena Barrasa, Cleide Barrigoto, Marie Bartoli, Joaquín Baruch, Romain Basmaci, Muhammad Fadhli Hassin Basri, AbdAlkarim Batool, Denise Battaglini, Jules Bauer, Diego Fernando Bautista Rincon, Denisse Bazan Dow, Abigail Beane, Alexandra Bedossa, Ker Hong Bee, Husna Begum, Sylvie Behilill, Albertus Beishuizen, Aleksandr Beljantsev, David Bellemare, Anna Beltrame, Beatriz Amorim Beltrão, Marine Beluze, Nicolas Benech, Lionel Eric Benjiman, Suzanne Bennett, Luís Bento, Jan-Erik Berdal, Lamis Berdeweel, Delphine Bergeaud, Hazel Bergin, Giulia Bertoli, Lorenzo Bertolino, Simon Bessis, Sybille Bevilcaqua, Karine Bezulier, Amar Bhatt, Krishna Bhavsar, Isabella Bianchi, Claudia Bianco, Sandra Bichoka, Farah Nadiah Bidin, Felwa Bin Humaid, Mohd Nazlin Bin Kamarudin, Muhannud Binnawara, Zeno Bisoffi, Patrick Biston, Laurent Bitker, Mustapha Bittaye, Jonathan Bitton, Pablo Blanco-Schweizer, Catherine Blier, Frank Bloos, Mathieu Blot, Filomena Boccia, Laetitia Bodenes, Debby Bogaert, Anne-Hélène Boivin, Ariel Bolanga, Isabela Bolaños, Pierre-Adrien Bolze, François Bompart, Aurelius Bonifasius, Joe Bonney, Diogo Borges, Raphaël Borie, Hans Martin Bosse, Elisabeth Botelho-Nevers, Lila Bouadma, Olivier Bouchaud, Sabelline Bouchez, Damien Bouhour, Kévin Bouiller, Laurence Bouillet, Camile Bouisse, Latsaniphone Bountthasavong, Anne-Sophie Boureau, John Bourke, Maude Bouscambert, Aurore Bousquet, Marielle Boyer-Besseyre, Maria Boylan, Fernando Augusto Bozza, Axelle Braconnier, Cynthia Braga, Timo Brandenburger, Filipa Brás Monteiro, Luca Brazzi, Dorothy Breen, Patrick Breen, David Brewster, Kathy Brickell, Tessa Broadley, Helen Brotherton, Alex Browne, Nicolas Brozzi, Sonja Hjellegjerde Brunvoll, Marjolein Brusse-Keizer, Petra Bryda, Nina Buchtele, Polina Bugaeva, Marielle Buisson, Danilo Buonsenso, Erlina Burhan, Donald Buri, Aidan Burrell, Ingrid G. Bustos, Denis Butnaru, André Cabie, Susana Cabral, Joana Cabrita, Eder Caceres, Cyril Cadoz, Rui Caetano Garcês, Kate Calligy, Jose Andres Calvache, João Camões, Valentine Campana, Paul Campbell, Josie Campisi, Cecilia Canepa, Mireia Cantero, Janice Caoili, Pauline Caraux-Paz, Sheila Cárcel, Filipa Cardoso, Filipe Cardoso, Nelson Cardoso, Sofia Cardoso, Simone Carelli, Nicolas Carlier, Thierry Carmoi, Gayle Carney, Inês Carqueja, Marie-Christine Carret, François Martin Carrier, Ida Carroll, Gail Carson, Maire-Laure Casanova, Mariana Cascão, Siobhan Casey, José Casimiro, Bailey Cassandra, Silvia Castañeda, Nidyanara Castanheira, Guylaine Castor-Alexandre, Ivo Castro, Ana Catarino, François-Xavier Catherine, Paolo Cattaneo, Roberta Cavalin, Giulio Giovanni Cavalli, Alexandros Cavayas, Adrian Ceccato, Masaneh Ceesay, Shelby Cerkovnik, Minerva Cervantes-Gonzalez, Muge Cevik, Anissa Chair, Catherine Chakveatze, Adrienne Chan, Meera Chand, Jean-Marc Chapplain, Charlotte Charpentier, Julie Chas, Muhammad Mobin Chaudry, Jonathan Samuel Chávez Iñiguez, Anjellica Chen, Yih-Sharng Chen, Léo Chenard, Matthew Pellan Cheng, Antoine Cheret, Thibault Chiarabini, Julian Chica, Suresh Kumar Chidambaram, Leong Chin Tho, Catherine Chirouze, Davide Chiumello, Sung-Min Cho, Bernard Cholley, Danoy Chommanam, Marie-Charlotte Chopin, Yock Ping Chow, Ting Soo Chow, Nathaniel Christy, Hiu Jian Chua, Jonathan Chua, Jose Pedro Cidade, José Miguel Cisneros Herreros, Barbara Wanjiru Citarella, Anna Ciullo, Jennifer Clarke, Rolando Claure-Del Granado, Sara Clohisey, Cassidy Codan, Caitriona Cody, Jennifer Coles, Megan Coles, Gwenhaël Colin, Michael Collins, Pamela Combs, Jennifer Connolly, Marie Connor, Anne Conrad, Elaine Conway, Graham S. Cooke, Hugues Cordel, Amanda Corley, Sabine Cornelis, Alexander Daniel Cornet, Arianne Joy Corpuz, Andrea Cortegiani, Grégory Corvaisier, Camille Couffignal, Sandrine Couffin-Cadiergues, Roxane Courtois, Stéphanie Cousse, Juthaporn Cowan, Rachel Cregan, Gloria Crowl, Jonathan Crump, Claudina Cruz, Marc Csete, Ailbhe Cullen, Matthew Cummings, Gerard Curley, Elodie Curlier, Colleen Curran, Paula Custodio, Ana da Silva Filipe, Charlene Da Silveira, Al-Awwab Dabaliz, Andrew Dagens, John Arne Dahl, Darren Dahly, Umberto D'Alessandro, Peter Daley, Zaina Dalloul, Heidi Dalton, Jo Dalton, Seamus Daly, Juliana Damas, Joycelyn Dame, Cammandji Damien, Nick Daneman, Jorge Dantas, Frédérick D'Aragon, Gillian de Loughry, Diego de Mendoza, Etienne De Montmollin, Rafael Freitas de Oliveira França, Ana Isabel de Pinho Oliveira, Rosanna De Rosa, Cristina De Rose, Thushan de Silva, Peter de Vries, Jillian Deacon, David Dean, Alexa Debard, Bianca DeBenedictis, Marie-Pierre Debray, Nathalie DeCastro, William Dechert, Romain Decours, Eve Defous, Isabelle Delacroix, Alexandre Delamou, Eric Delaveuve, Karen Delavigne, Nathalie M. Delfos, Ionna Deligiannis, Andrea Dell'Amore, Christelle Delmas, Pierre Delobel, Corine Delsing, Elisa Demonchy, Emmanuelle Denis, Dominique Deplanque, Pieter Depuydt, Diane Descamps, Mathilde Desvallées, Santi Dewayanti, Pathik Dhangar, Alpha Diallo, Souleymane Taran Diallo, Sylvain Diamantis, André Dias, Fernanda Dias Da Silva, Rodrigo Diaz, Juan Jose Diaz, Priscila Diaz, Bakary K. Dibba, Kévin Didier, Jean-Luc Diehl, Wim Dieperink, Jérôme Dimet, Vincent Dinot, Fara Diop, Alphonsine Diouf, Yael Dishon, Cedric Djadda, Félix Djossou, Annemarie B. Docherty, Helen Doherty, Arjen M. Dondorp, Christl A. Donnelly, Yoann Donohue, Sean Donohue, Peter Doran, Céline Dorival, Eric D'Ortenzio, Yash Doshi, Phouvieng Douangdala, James Joshua Douglas, Renee Douma, Nathalie Dournon, Joanne Downey, Mark Downing, Thomas Drake, Aoife Driscoll, Ibrahim Kwaku Duah, Claudio Duarte Fonseca, Vincent Dubee, François Dubos, Audrey Dubot-Pérès, Alexandre Ducancelle, Toni Duculan, Susanne Dudman, Abhijit Duggal, Paul Dunand, Jake Dunning, Mathilde Duplaix, Emanuele Durante-Mangoni, Lucian Durham, Bertrand Dussol, Juliette Duthoit, Xavier Duval, Anne Margarita Dyrhol-Riise, Sim Choon Ean, Ada Ebo, Marco Echeverria-Villalobos, Michael Edelstein, Siobhan Egan, Linn Margrete Eggesbø, Khadeja Ehzaz, Carla Eira, Mohammed El Sanharawi, Marwan El Sayed, Mohammed Elabid, Mohamed Bashir Elagili, Subbarao Elapavaluru, Mohammad Elbahnasawy, Sohail Elboshra, Brigitte Elharrar, Jacobien Ellerbroek, Merete Ellingjord-Dale, Hamida ELMagrahi, Mohammad Muatasm Elmubark, Loubna Elotmani, Lauren Eloundou, Philippine Eloy, Basma Elshaikhy, Tarek Elshazly, Wafa Elsokni, Aml Ahmed Eltayeb, Iqbal Elyazar, Zarief Kamel Emad, Hussein Embarek, Isabelle Enderle, Tomoyuki Endo, Gervais Eneli, Chan Chee Eng, Ilka Engelmann, Vincent Enouf, Olivier Epaulard, Haneen Esaadi, Mariano Esperatti, Hélène Esperou, Catarina Espírito Santo, Marina Esposito-Farese, Rachel Essaka, Lorinda Essuman, João Estevão, Manuel Etienne, Anna Greti Everding, Mirjam Evers, Isabelle Fabre, Marc Fabre, Ismaila Fadera, Asgad Osman Abdalla Fadlalla, Amna Faheem, Arabella Fahy, Cameron J. Fairfield, Zul Fakar, Komal Fareed, Pedro Faria, Ahmed Farooq, Hanan Fateena, Mohamed Fathi, Salem Fatima, Arie Zainul Fatoni, Karine Faure, Raphaël Favory, Mohamed Fayed, Niamh Feely, Jorge Fernandes, Marília Andreia Fernandes, Susana Fernandes, François-Xavier Ferrand, Eglantine Ferrand Devouge, Joana Ferrão, Mário Ferraz, Benigno Ferreira, Isabel Ferreira, Bernardo Ferreira, Sílvia Ferreira, Nicolas Ferriere, Céline Ficko, Claudia Figueiredo-Mello, William Finlayson, Thomas Flament, Tom Fletcher, Aline-Marie Florence, Letizia Lucia Florio, Brigid Flynn, Deirdre Flynn, Jean Foley, Victor Fomin, Tatiana Fonseca, Patricia Fontela, Karen Forrest, Simon Forsyth, Denise Foster, Giuseppe Foti, Berline Fotso, Erwan Fourn, Robert A. Fowler, Marianne Fraher, Diego Franch-Llasat, Christophe Fraser, John F. Fraser, Marcela Vieira Freire, Ana Freitas Ribeiro, Craig French, Caren Friedrich, Ricardo Fritz, Stéphanie Fry, Nora Fuentes, Masahiro Fukuda, G. Argin, Valérie Gaborieau, Rostane Gaci, Massimo Gagliardi, Jean-Charles Gagnard, Amandine Gagneux-Brunon, Abdou Gai, Sérgio Gaião, Linda Gail Skeie, Adham Mohamed Galal Mohamed Ramadan, Phil Gallagher, Carrol Gamble, Yasmin Gani, Arthur Garan, Rebekha Garcia, Julia Garcia-Diaz, Esteban Garcia-Gallo, Navya Garimella, Denis Garot, Valérie Garrait, Basanta Gauli, Anatoliy Gavrylov, Alexandre Gaymard, Johannes Gebauer, Eva Geraud, Louis Gerbaud Morlaes, Nuno Germano, Malak Ghemmeid, Praveen Kumar Ghisulal, Jade Ghosn, Marco Giani, Tristan Gigante, Elaine Gilroy, Guillermo Giordano, Michelle Girvan, Valérie Gissot, Gezy Giwangkancana, Daniel Glikman, Petr Glybochko, Eric Gnall, Geraldine Goco, François Goehringer, Siri Goepel, Jean-Christophe Goffard, Jin Yi Goh, Brigitta Golács, Jonathan Golob, Kyle Gomez, Joan Gómez-Junyent, Marie Gominet, Alicia Gonzalez, Patricia Gordon, Isabelle Gorenne, Laure Goubert, Cécile Goujard, Tiphaine Goulenok, Margarite Grable, Jeronimo Graf, Edward Wilson Grandin, Pascal Granier, Giacomo Grasselli, Lorenzo Grazioli, Christopher A. Green, Courtney Greene, William Greenhalf, Segolène Greffe, Domenico Luca Grieco, Matthew Griffee, Fiona Griffiths, Ioana Grigoras, Albert Groenendijk, Fassou Mathias Grovogui, Heidi Gruner, Yusing Gu, Jérémie Guedj, Martin Guego, Anne-Marie Guerguerian, Daniela Guerreiro, Romain Guery, Anne Guillaumot, Laurent Guilleminault, Maisa Guimarães de Castro, Thomas Guimard, Marieke Haalboom, Daniel Haber, Ali Hachemi, Abdurrahman Haddud, Nadir Hadri, Wael Hafez, Fakhir Raza Haidri, Fatima Mhd Rida Hajij, Sheeba Hakak, Adam Hall, Matthew Hall, Sophie Halpin, Shaher Hamdan, Abdelhafeez Hamdi, Jawad Hameed, Ansley Hamer, Raph L. Hamers, Rebecca Hamidfar, Bato Hammarström, Naomi Hammond, Terese Hammond, Lim Yuen Han, Matly Hanan, Rashan Haniffa, Kok Wei Hao, Hayley Hardwick, Ewen M. Harrison, Janet Harrison, Samuel Bernard Ekow Harrison, Alan Hartman, Sulieman Hasan, Mohammad Ali Nabil Hasan, Mohd Shahnaz Hasan, Junaid Hashmi, Madiha Hashmi, Amoni Hassan, Ebtisam Hassanin, Muhammad Hayat, Ailbhe Hayes, Leanne Hays, Jan Heerman, Lars Heggelund, Ahmed Helmi, Ross Hendry, Martina Hennessy, Aquiles Rodrigo Henriquez-Trujillo, Maxime Hentzien, Diana Hernandez, Andrew Hershey, Liv Hesstvedt, Astarini Hidayah, Eibhlin Higgins, Rupert Higgins, Samuel Hinton, Hiroaki Hiraiwa, Haider Hirkani, Hikombo Hitoto, Antonia Ho, Yi Bin Ho, Alexandre Hoctin, Isabelle Hoffmann, Wei Han Hoh, Oscar Hoiting, Rebecca Holt, Jan Cato Holter, Peter Horby, Juan Pablo Horcajada, Ikram Houas, Mabrouka Houderi, Catherine L. Hough, Stuart Houltham, Jimmy Ming-Yang Hsu, Jean-Sébastien Hulot, Abby Hurd, Iqbal Hussain, Aliae Mohamed Hussein, Mahmood Hussein, Fatima Ibrahim, Bashir Ibran, Samreen Ijaz, M. Arfan Ikram, Carlos Cañada Illana, Patrick Imbert, Muhammad Imran Ansari, Rana Imran Sikander, Hugo Inácio, Carmen Infante Dominguez, Yun Sii Ing, Mariachiara Ippolito, Vera Irawany, Sarah Isgett, Tiago Isidoro, Nadiah Ismail, Margaux Isnard, Mette Stausland Istre, Junji Itai, Daniel Ivulich, Danielle Jaafar, Salma Jaafoura, Hamza Jaber, Julien Jabot, Clare Jackson, Abubacarr Jagne, Stéphane Jaureguiberry, Denise Jaworsky, Florence Jego, Anilawati Mat Jelani, Synne Jenum, Ruth Jimbo-Sotomayor, Ong Yiaw Joe, Ruth Noemí Jorge García, Silje Bakken Jørgensen, Cédric Joseph, Mark Joseph, Swosti Joshi, Mercé Jourdain, Philippe Jouvet, Anna Jung, Hanna Jung, Dafsah Juzar, Ouifiya Kafif, Florentia Kaguelidou, Neerusha Kaisbain, Thavamany Kaleesvran, Sabina Kali, Karl Trygve Kalleberg, Smaragdi Kalomoiri, Muhammad Aisar Ayadi Kamaluddin, Armand Saloun Kamano, Zul Amali Che Kamaruddin, Nadiah Kamarudin, Kavita Kamineni, Darshana Hewa Kandamby, Kong Yeow Kang, Darakhshan Kanwal, Dyah Kanyawati, Mohamed Karghul, Pratap Karpayah, Todd Karsies, Christiana Kartsonaki, Daisuke Kasugai, Kevin Katz, Christy Kay, Lamees Kayyali, Seán Keating, Pulak Kedia, Andrea Kelly, Aoife Kelly, Claire Kelly, Niamh Kelly, Sadie Kelly, Yvelynne Kelly, Maeve Kelsey, Kalynn Kennon, Sommay Keomany, Maeve Kernan, Younes Kerroumi, Sharma Keshav, Shams Khail, Sarah Khaled, Imrana Khalid, Antoine Khalil, Irfan Khan, Quratul Ain Khan, Sushil Khanal, Abid Khatak, Krish Kherajani, Michelle E. Kho, Denisa Khoo, Ryan Khoo, Saye Khoo, Muhammad Nasir Khoso, Amin Khuwaja, Khor How Kiat, Yuri Kida, Peter Kiiza, Beathe Kiland Granerud, Anders Benjamin Kildal, Jae Burm Kim, Antoine Kimmoun, Detlef Kindgen-Milles, Nobuya Kitamura, Eyrun Floerecke Kjetland Kjetland, Paul Klenerman, Rob Klont, Gry Kloumann Bekken, Stephen R. Knight, Robin Kobbe, Paa Kobina Forson, Chamira Kodippily, Malte Kohns Vasconcelos, Sabin Koirala, Mamoru Komatsu, Franklina Korkor Abebrese, Volkan Korten, Stephanie Kouba, Mohamed Lamine Kourouma, Karifa Kourouma, Arsène Kpangon, Karolina Krawczyk, Ali Kredan, Vinothini Krishnan, Sudhir Krishnan, Oksana Kruglova, Anneli Krund, Pei Xuan Kuan, Ashok Kumar, Deepali Kumar, Ganesh Kumar, Mukesh Kumar, Dinesh Kuriakose, Ethan Kurtzman, Demetrios Kutsogiannis, Galyna Kutsyna, Ama Kwakyewaa Bedu-Addo, Sylvie Kwedi, Konstantinos Kyriakoulis, Marie Lachatre, Marie Lacoste, John G. Laffey, Nadhem Lafhej, Marie Lagrange, Fabrice Laine, Olivier Lairez, Sanjay Lakhey, Marc Lambert, François Lamontagne, Marie Langelot-Richard, Vincent Langlois, Eka Yudha Lantang, Marina Lanza, Cédric Laouénan, Samira Laribi, Delphine Lariviere, Stéphane Lasry, Sakshi Lath, Naveed Latif, Youssef Latifeh, Odile Launay, Didier Laureillard, Yoan Lavie-Badie, Andy Law, Cassie Lawrence, Teresa Lawrence, Minh Le, Clément Le Bihan, Cyril Le Bris, Georges Le Falher, Lucie Le Fevre, Quentin Le Hingrat, Marion Le Maréchal, Soizic Le Mestre, Gwenaël Le Moal, Vincent Le Moing, Hervé Le Nagard, Ema Leal, Marta Leal Santos, Biing Horng Lee, Heng Gee Lee, Su Hwan Lee, James Lee, Jennifer Lee, Todd C. Lee, Yi Lin Lee, Gary Leeming, Bénédicte Lefebvre, Laurent Lefebvre, Benjamin Lefèvre, Sylvie LeGac, Merili-Helen Lehiste, Jean-Daniel Lelievre, François Lellouche, Adrien Lemaignen, Véronique Lemee, Anthony Lemeur, Gretchen Lemmink, Ha Sha Lene, Jenny Lennon, Rafael León, Marc Leone, Tanel Lepik, Quentin Lepiller, François-Xavier Lescure, Olivier Lesens, Mathieu Lesouhaitier, Amy Lester-Grant, Andrew Letizia, Sophie Letrou, Bruno Levy, Yves Levy, Claire Levy-Marchal, Katarzyna Lewandowska, Erwan L'Her, Gianluigi Li Bassi, Janet Liang, Ali Liaquat, Geoffrey Liegeon, Kah Chuan Lim, Wei Shen Lim, Chantre Lima, Bruno Lina, Lim Lina, Andreas Lind, Maja Katherine Lingad, Guillaume Lingas, Sylvie Lion-Daolio, Keibun Liu, Marine Livrozet, Patricia Lizotte, Antonio Loforte, Navy Lolong, Leong Chee Loon, Diogo Lopes, Dalia Lopez-Colon, Anthony L. Loschner, Paul Loubet, Bouchra Loufti, Guillame Louis, Silvia Lourenco, Lara Lovelace-Macon, Lee Lee Low, Marije Lowik, Jia Shyi Loy, Jean Christophe Lucet, Carlos M. Luna, Olguta Lungu, Miles Lunn, Liem Luong, Nestor Luque, Dominique Luton, Olavi Maasikas, Moïse Machado, Sara Machado, Gabriel Macheda, Mustafa Magzoub, Rafael Mahieu, Sophie Mahy, Ana Raquel Maia, Lars S. Maier, Oumou Maiga Ascofare, Mylène Maillet, Thomas Maitre, Nimisha Abdul Majeed, Maximilian Malfertheiner, Nadia Malik, Paddy Mallon, Fernando Maltez, Denis Malvy, Victoria Manda, Laurent Mandelbrot, Frank Manetta, Julie Mankikian, Edmund Manning, Aldric Manuel, Veronika Maráczi, Ceila Maria Sant′Ana Malaque, Flávio Marino, Samuel Markowicz, Ana Marques, Catherine Marquis, Laura Marsh, Brian Marsh, Megan Marshal, John Marshall, Celina Turchi Martelli, Dori-Ann Martin, Emily Martin, Guillaume Martin-Blondel, Alessandra Martinelli, F. Eduardo Martinez, Ignacio Martin-Loeches, Martin Martinot, Alejandro Martín-Quiros, Ana Martins, João Martins, Nuno Martins, Caroline Martins Rego, Gennaro Martucci, Olga Martynenko, Eva Miranda Marwali, Marsilla Marzukie, David Maslove, Sabina Mason, Sobia Masood, Fatma Masoud, Moise Massoma, Palmer Masumbe, Mohd Basri Mat Nor, Moshe Matan, Henrique Mateus Fernandes, Meghena Mathew, Christina Mathew, Mathieu Mattei, Laurence Maulin, Juergen May, Javier Maynar, Mayfong Mayxay, Thierry Mazzoni, Lisa Mc Sweeney, Colin McArthur, Naina McCann, Peter McCanny, Aine McCarthy, Anne McCarthy, Colin McCloskey, Rachael McConnochie, Sherry McDermott, Sarah E. McDonald, Aine McElroy, Samuel McElwee, Natalie McEvoy, Allison McGeer, Kenneth A. McLean, Paul McNally, Bairbre McNicholas, Edel Meaney, Cécile Mear-Passard, Maggie Mechlin, Nastia Medombou, Omar Mehkri, Ferruccio Mele, Luis Melo, Kashif Ali Memon, João João Mendes, Ogechukwu Menkiti, Kusum Menon, France Mentré, Alexander J. Mentzer, Emmanuelle Mercier, Noémie Mercier, Antoine Merckx, Mayka Mergeay-Fabre, Blake Mergler, Laura Merson, António Mesquita, Roberta Meta, Osama Metwally, Agnès Meybeck, Dan Meyer, Alison M. Meynert, Vanina Meysonnier, Mehdi Mezidi, Céline Michelanglei, Isabelle Michelet, Efstathia Mihelis, Vladislav Mihnovit, Duha Milad Abdullah, Jennene Miller, Hugo Miranda-Maldonado, Nor Arisah Misnan, Nik Nur Eliza Mohamed, Nouralsabah Mohamed, Tahira Jamal Mohamed, Alaa Mohamed Ads, Ahmed Reda Mohamed Elsayed Abdelhalim, Libya Mohammed, Shrouk Fawze Mohammed Mostafa, Manahil Omer Abdelrahman Mohammedahmed, Omer Abdullah Mohammedelhassan, Asma Moin, Walaa Mokhtar, Elena Molinos, Brenda Molloy, Mary Mone, Agostinho Monteiro, Claudia Montes, Giorgia Montrucchio, Sarah Moore, Shona C. 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    Lancet, 2022
  • SARS-CoV-2 Omicron Variant, Lineage BA.1, Is Associated with Lower Viral Load in Nasopharyngeal Samples Compared to Delta Variant
    Célia Sentis, Geneviève Billaud, Antonin Bal, Emilie Frobert, Maude Bouscambert, Gregory Destras, Laurence Josset, Bruno Lina, Florence Morfin, Alexandre Gaymard, and
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  • Effect of remdesivir on viral dynamics in COVID-19 hospitalized patients: a modelling analysis of the randomized, controlled, open-label DisCoVeRy trial
    Guillaume Lingas, Nadège Néant, Alexandre Gaymard, Drifa Belhadi, Gilles Peytavin, Maya Hites, Thérèse Staub, Richard Greil, Jose-Artur Paiva, Julien Poissy, Nathan Peiffer-Smadja, Dominique Costagliola, Yazdan Yazdanpanah, Florent Wallet, Amandine Gagneux-Brunon, France Mentré, Florence Ader, Charles Burdet, Jérémie Guedj, Maude Bouscambert-Duchamp
    Journal of Antimicrobial Chemotherapy, 2022
  • Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled, open-label trial
    Florence Ader, Maude Bouscambert-Duchamp, Maya Hites, Nathan Peiffer-Smadja, Julien Poissy, Drifa Belhadi, Alpha Diallo, Minh-Patrick Lê, Gilles Peytavin, Thérèse Staub, Richard Greil, Jérémie Guedj, Jose-Artur Paiva, Dominique Costagliola, Yazdan Yazdanpanah, Charles Burdet, France Mentré, Alexander Egle, Richard Greil, Michael Joannidis, Bernd Lamprecht, Antoine Altdorfer, Leila Belkhir, Vincent Fraipont, Maya Hites, Gil Verschelden, Jérôme Aboab, Florence Ader, Hafid Ait-Oufella, Claire Andrejak, Pascal Andreu, Laurent Argaud, Firouzé Bani-Sadr, François Benezit, Mathieu Blot, Elisabeth Botelho-Nevers, Lila Bouadma, Olivier Bouchaud, David Bougon, Kevin Bouiller, Fanny Bounes-Vardon, David Boutoille, Alexandre Boyer, Cédric Bruel, André Cabié, Emmanuel Canet, Charles Cazanave, Cyrille Chabartier, Catherine Chirouze, Raphaël Clere-Jehl, Johan Courjon, Flora Crockett, François Danion, Agathe Delbove, Jean Dellamonica, Félix Djossou, Clément Dubost, Alexandre Duvignaud, Olivier Epaulard, Loïc Epelboin, Murielle Fartoukh, Karine Faure, Emmanuel Faure, Tristan Ferry, Cécile Ficko, Samy Figueiredo, Benjamin Gaborit, Rostane Gaci, Amandine Gagneux-Brunon, Sébastien Gallien, Denis Garot, Guillaume Geri, Sébastien Gibot, François Goehringer, Marie Gousseff, Didier Gruson, Yves Hansmann, Olivier Hinschberger, Stéphane Jaureguiberry, Vanessa Jeanmichel, Solen Kerneis, Antoine Kimmoun, Kada Klouche, Marie Lachâtre, Karine Lacombe, Fabrice Laine, Jean-Philippe Lanoix, Odile Launay, Bruno Laviolle, Vincent Le Moing, Jérôme Le Pavec, Yves Le Tulzo, Paul Le Turnier, David Lebeaux, Benjamin Lefevre, Sylvie Leroy, François-Xavier Lescure, Henry Lessire, Benjamin Leveau, Paul Loubet, Alain Makinson, Denis Malvy, Charles-Hugo Marquette, Guillaume Martin-Blondel, Martin Martinot, Julien Mayaux, Armand Mekontso-Dessap, Ferhat Meziani, Jean-Paul Mira, Jean-Michel Molina, Xavier Monnet, Joy Mootien, Bruno Mourvillier, Marlène Murris-Espin, Jean-Christophe Navellou, Saad Nseir, Walid Oulehri, Nathan Peiffer-Smadja, Thomas Perpoint, Gilles Pialoux, Benoît Pilmis, Vincent Piriou, Lionel Piroth, Julien Poissy, Valérie Pourcher, Jean-Pierre Quenot, François Raffi, Jean Reignier, Matthieu Revest, Jean-Christophe Richard, Béatrice Riu-Poulenc, Céline Robert, Pierre-Alexandre Roger, Claire Roger, Elisabeth Rouveix-Nordon, Yvon Ruch, Nadia Saidani, Naomi Sayre, Eric Senneville, Albert Sotto, Francois Stefan, Charles Tacquard, Nicolas Terzi, Julien Textoris, Guillaume Thiery, Jean-François Timsit, Violaine Tolsma, Jean-Marie Turmel, Florent Valour, Florent Wallet, Guilhem Wattecamps, Yazdan Yazdanpanah, Yoann Zerbib, Marc Berna, Jean Reuter, Thérèse Staub, Sandra Braz, Joao-Miguel Ferreira Ribeiro, José-Artur Paiva, Roberto Roncon-Albuquerque, Maude Bouscambert-Duchamp, Alexandre Gaymard, Minh-Patrick Lê, Bruno Lina, Gilles Peytavin, Sarah Tubiana, Sandrine Couffin-Cadièrgues, Hélène Esperou, Drifa Belhadi, Charles Burdet, Dominique Costagliola, Aline Dechanet, Christelle Delmas, Alpha Diallo, Claire Fougerou, Jérémie Guedj, France Mentré, Noémie Mercier, Marion Noret, Juliette Saillard, Priyanka Velou
    Lancet Infectious Diseases, 2022
  • Dynamics of viral shedding during ancestral or Omicron BA.1 SARS-CoV-2 infection and enhancement of pre-existing immunity during breakthrough infections
    Carla Saade, Karen Brengel-Pesce, Alexandre Gaymard, Mary-Anne Trabaud, Gregory Destras, Guy Oriol, Valérie Cheynet, Marion Debombourg, Bouchra Mokdad, Geneviève Billaud, Antoine Oblette, Hervé Créhalet, Jean-Marc Giannoli, Christine Garrigou, Laurence Generenaz, Christelle Compagnon, André Boibieux, Bruno Lina, Florence Morfin, Bruno Pozzetto, Laurence Josset, Sophie Touillet-Assant, Antonin Bal
    Emerging Microbes and Infections, 2022
  • Clinical and laboratory characteristics of symptomatic healthcare workers with suspected COVID-19: a prospective cohort study
    Antonin Bal, Karen Brengel-Pesce, Alexandre Gaymard, Grégory Quéromès, Nicolas Guibert, Emile Frobert, Maude Bouscambert, Mary-Anne Trabaud, Florence Allantaz-Frager, Guy Oriol, Valérie Cheynet, Constance d’Aubarede, Amélie Massardier-Pilonchery, Marlyse Buisson, Julien Lupo, Bruno Pozzetto, Pascal Poignard, Bruno Lina, Jean-Baptiste Fassier, Florence Morfin, Sophie Trouillet-Assant, Jerôme Adnot, Dulce Alfaiate, Alain Bergeret, André Boibieux, Florent Bonnet, Florence Brunel-Dalmas, Eurydice Caire, Barbara Charbotel, Pierre Chiarello, Laurent Cotte, Constance d’Aubarede, François Durupt, Vanessa Escuret, Pascal Fascia, Juliette Fontaine, Lucie Gaillot-Durand, Myriam Gillet, Matthieu Godinot, François Gueyffier, Laurence Josset, Matthieu Lahousse, Hélène Lozano, Djamila Makhloufi, Marie-Paule Milon, Frédéric Moll, David Narbey, Julie-Anne Nazare, Fatima Oria, Marielle Perry, Virginie Pitiot, Mélanie Prudent, Muriel Rabilloud, Audrey Samperiz, Isabelle Schlienger, Chantal Simon, Martine Valette, and
    Scientific Reports, 2021
  • Publisher Correction: Clinical and laboratory characteristics of symptomatic healthcare workers with suspected COVID-19: a prospective cohort study (Scientific Reports, (2021), 11, 1, (14977), 10.1038/s41598-021-93828-y)
    Antonin Bal, Karen Brengel-Pesce, Alexandre Gaymard, Grégory Quéromès, Nicolas Guibert, Emilie Frobert, Maude Bouscambert, Mary-Anne Trabaud, Florence Allantaz-Frager, Guy Oriol, Valérie Cheynet, Constance d’Aubarede, Amélie Massardier-Pilonchery, Marlyse Buisson, Julien Lupo, Bruno Pozzetto, Pascal Poignard, Bruno Lina, Jean-Baptiste Fassier, Florence Morfin, Sophie Trouillet-Assant, Jerôme Adnot, Dulce Alfaiate, Alain Bergeret, André Boibieux, Florent Bonnet, Florence Brunel-Dalmas, Eurydice Caire, Barbara Charbotel, Pierre Chiarello, Laurent Cotte, Constance d’Aubarede, François Durupt, Vanessa Escuret, Pascal Fascia, Juliette Fontaine, Lucie Gaillot-Durand, Myriam Gillet, Matthieu Godinot, François Gueyffier, Laurence Josset, Matthieu Lahousse, Hélène Lozano, Djamila Makhloufi, Marie-Paule Milon, Frédéric Moll, David Narbey, Julie-Anne Nazare, Fatima Oria, Marielle Perry, Virginie Pitiot, Mélanie Prudent, Muriel Rabilloud, Audrey Samperiz, Isabelle Schlienger, Chantal Simon, Martine Valette, and
    Scientific Reports, 2021
  • Chronic use of renin-angiotensin-aldosterone system blockers and mortality in COVID-19: A multicenter prospective cohort and literature review
    Nathalie Gault, Marina Esposito‐Farèse, Matthieu Revest, Jocelyn Inamo, André Cabié, Élisabeth Polard, Jean‐Sébastien Hulot, Jade Ghosn, Catherine Chirouze, Laurène Deconinck, Jean‐Luc Diehl, Julien Poissy, Olivier Epaulard, Benjamin Lefèvre, Lionel Piroth, Etienne De Montmollin, Eric Oziol, Manuel Etienne, Cédric Laouénan, Patrick Rossignol, Dominique Costagliola, Emmanuelle Vidal‐Petiot, Marie Bartoli, Alpha Diallo, Soizic Le Mestre, Noémie Mercier, Christelle Paul, Ventzislava Petrov‐Sanchez, Claire Andrejak, Denis Malvy, François Dubos, François Bompart, Tristan Gigante, Morgane Gilg, Bénédicte Rossignol, Claire Léy‐Marchal, Marine Beluze, Delphine Bachelet, Krishna Bhavsar, Lila Bouadma, Anissa Chair, Camille Couffignal, Charlene Da Silveira, Marie‐Pierre Debray, Diane Descamps, Xavier Duval, Philippine Eloy, Marina Esposito‐Farèse, Nadia Ettalhaoui, Isabelle Gorenne, Isabelle Hoffmann, Ouifiya Kafif, Sabrina Kali, Antoine Khalil, Cédric Laouénan, Samira Laribi, Minh Lê, Quentin Le Hingrat, François‐Xavier Lescure, Jean‐Christophe Lucet, France Mentré, Jimmy Mullaert, Nathan Peiffer‐Smadja, Gilles Peytavin, Carine Roy, Marion Schneider, Nassima Si Mohammed, Lysa Tagherset, Coralie Tardivon, Marie‐Capucine Tellier, Jean‐François Timsit, Théo Trioux, Sarah Tubiana, Benoît Visseaux, Yazdan Yazdanpanah, Dominique Deplanque, Noémie Vanel, Romain Basmaci, Olivier Picone, François Angoulvant, Florentia Kaguelidou, Justine Pages, Christelle Tual, Aurélie Veislinger, Sandrine Couffin‐Cadiergues, Hélène Esperou, Ikram Houas, Salma Jaafoura, Aurélie Papadopoulos, Alexandra Coelho, Alphonsine Diouf, Alexandre Hoctin, Marina Mambert, Maude Bouscambert, Alexandre Gaymard, Bruno Lina, Manuel Rosa‐calatrava, Olivier Terrier, Dehbia Benkerrou, Céline Dorival, Amina Meziane, François Téoulé, Jérémie Guedj, Hervé Le Nagard, Guillaume Lingas, Nadège Neant, Laurent Abel, Mathilde Desvallée, Coralie Khan, Sylvie Behilill, Vincent Enouf, Hugo Mouquet, Sylvie Van der werf, Minerva Cervantes‐gonzalez, Eric D’Ortenzio, Oriane Puéchal, Caroline Semaille, Marion Noret, Yves Levy, Aurélie Wiedemann, Mélanie Roriz, Patrick Rispal, Sarah Redl, Laurent Lefebvre, Pascal Granier, Laurence Maulin, Cédric Joseph, Julien Moyet, Cinthia Rames, Rafael Mahieu, Alexandra Ducancelle, Vincent Dubee, Stéphane Sallaberry, Aldric Manuel, Gabriel Macheda, Mylène Maillet, Patrick Imbert, Amélie Valran, Jean‐Charles Gagnard, Guillermo Giordano, Clara Mouton Perrot, Vincent Pestre, Cécile Ficko, Marie Gominet, Aurore Bousquet, Charline Vauchy, Kévin Bouiller, Maïder Pagadoy, Quentin Lepiller, Noémie Tissot, Cyril Le Bris, Benoit Thill, Marie‐Laure Casanova, Georges Le Falher, Hugues Cordel, Nathalie Dournon, Olivier Bouchaud, Duc Nguyen, Segolène Greffe, Camille Bouisse, Nicholas Sedillot, Damien Bouhour, Camille Chassin, Erwan L'her, Laetitia Bodenes, Nicolas Ferriere, Séverine Ansart, Cécile Tromeur, Dewi Guellec, Antoine Merckx, Felix Djossou, Mayka Mergeayfabre, Arsène Kpangon, Vincent Peigne, Carola Pierobon, Marie‐Christine Carret, Florence Jego, Margaux Isnard, Johann Auchabie, Anthony Lemeur, Thierry Mazzoni, Roxane Courtois, Olivier Lesens, Martin Martinot, Jeanne Sibiude, Laurent Mandelbrot, Marie Lacoste, Jean‐Daniel Lelievre, Brigitte Elharrar, Valerie Garrait, Isabelle Delacroix, Thomas Maitre, Jean‐Baptiste Assie, Elsa Nyamankolly, Adrien Auvet, Anne‐Hélène Boivin, Younes Kerroumi, Vanina Meyssonnier, Oryane Mabiala, François Xavier Catherine, Mathieu Blot, Sophie Mahy, Marielle Buisson, Valentine Campana, Jérémie Pasquier, Pierre‐François Sandrine, Jean‐Marie Turmel, Simon Bessis, Nicolas Terzi, Jean‐François Payen, Laurence Bouillet, Rebecca Hamidfar, Marion Le Marechal, Elodie Curlier, Rachida Ouissa, Isabelle Fabre, Pierre‐Marie Roger, Samuel Markowicz, Olivier Picone, Cécile Goujard, Stéphane Jaureguiberry, Antoine Cheret, Gwenhaël Colin, Romain Decours, Thomas Guimard, Vincent Langlois, Laure Goubert, Stéphanie Cousse, Hikombo Hitoto, Saad Nseir, Sébastien Preau, Mercé Jourdain, Raphaël Favory, Karine Faure, Fanny Vuotto, Marie‐Charlotte Chopin, Sarah Stabler, Jules Bauer, Marc Lambert, Arnaud Scherpereel, Ryadh Pokeerbux, Stéphanie Fry, Cécile Yelnik, Laurent Bitker, Mehdi Mezidi, Hodane Yonis, Nicolas Benech, Thomas Perpoint, Anne Conrad, Muriel Doret‐Dion, Pierre‐Adrien Bolze, Simon‐Djamel Thiberville, Moïse Machado, Audrey Barrelet, Alexandra Bedossa, Stanislas Rebaudet, Frédérique Retornaz, Myriam Bennani, Hortense Drouet, Bertrand Dussol, Marc Leone, Bruno Pastene, Karine Bezulier, Axelle Braconnier, Sylvain Diamantis, Catherine Chakveatze, Clara Flateau, Vincent Dinot, Rostane Gaci, Nadia Ouamara, Guillaume Louis, Cyril Cadoz, Hajnal‐Gabriela Illes, Bouchra Loutfi, Jérôme Dimet, Vincent Le Moing, Nathalie Pansu, Clément Le Bihan, Antoine Kimmoun, Bruno Levy, Maximilen Saint Gilles, François Goehringer, Christian Rabaud, Sibylle Bevilacqua, Benjamin Lefèvre, Anne Guillaumot, Anne‐Sophie Boureau, Clotilde Allavena, Sabelline Bouchez, Romain Guery, Paul Le Turnier, Cécile Mear‐Passard, Christophe Rapp, Stéphane Lasry, Thierry Carmoi, Elisa Demonchy, Céline Michelangelli, Karine Risso, Paul Loubet, Alberto Sotto, Didier Laureillard, Etienne De Montmollin, Juliette Patrier, Paul Henri Wicky, Lucie Lefevre, Pierre Jacquet, Raphael Borie, Tiphaine Goulenok, Dominique Luton, Laurène Deconinck, Sylvie Le Gac, Cecile Azoulay, Nicolas Carlier, Liem Luong, Marie Lachatre, Odile Launay, Marine Livrozet, Bernard Cholley, Jean‐Benoit Arlet, Olivier Sanchez, Victoria Manda, Laurène Azemar, Guylaine Castor‐Alexandre, Jeanne Truong, Karine Lacombe, Thibault Chiarabini, Bénédicte Lefebvre, Nathalie De Castro, Geoffrey Liegeon, Diane Ponscarme, Julie Chas, Valérie Gaborieau, Eve Le Coustumier, Walter Picard, Jean‐Benoit Zabbe, Florent Peelman, Edouard Soum, Hugues Aumaître, Blandine Rammaert, Gwenaël Le Moal, Isabelle Pironneau, Anne Sophie Resseguier, Nadia Saidani, Firouzé Bani‐Sadr, Maxime Hentzien, Yohan N'guyen, Juliette Romaru, Kévin Didier, Isabelle Enderle, Fabrice Laine, Matthieu Lesouhaitier, Pierre Tattevin, Jean‐Marc Chapplain, Véronique Lemee, Eglantine Ferrand Devouge, Kévin Alexandre, Elise Artaud‐Maccari, Nathalie Allou, Marie Lagrange, Julien Jabot, Elisabeth Botelho‐Nevers, Amandine Gagneux‐Brunon, Tiffany Trouillon, Corinne Daniel, Benoît Roze, Delphine Bregeaud, Younes Ait Tamlihat, Ali Hachemi, Hélène Salvator, Erwan Fourn, David Zucman, Marie‐Laure Chabi‐Chavillat, Aurélie Martin, Eric Delaveuve, Coline Jaud‐Fischer, Paul Dunand, François Bissuel, Karen Delavigne, Alexa Debard, Pierre Delobel, Benjamine Sarton, Stella Rousset, Guillaume Martin‐Blondel, Laurent Guilleminault, Marlène Murris, Agnès Sommet, Olivier Lairez, Eric Senneville, Olivier Robineau, Agnès Meybeck, Denis Garot, Laurent Plantier, Valérie Gissot, Emmanuelle Mercier, Charlotte Salmon Gandonniere, Adrien Lemaignen, Julie Mankikian, Thomas Flament, Grégory Corvaisier, Delphine Lariviere, Marie Langelot‐Richard, Pauline Caraux Paz, Laurent Richier, Danielle Jaafar, Claudine Badr, Fara Diop, and
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  • The value of open-source clinical science in pandemic response: lessons from ISARIC
    Ali Abbas, Sheryl Ann Abdukahil, Nurul Najmee Abdulkadir, Ryuzo Abe, Laurent Abel, Lara Absil, Subhash Acharya, Andrew Acker, Shingo Adachi, Elisabeth Adam, Diana Adrião, Saleh Al Ageel, Shakeel Ahmed, Quratul Ain, Kate Ainscough, Tharwat Aisa, Ali Ait Hssain, Younes Ait Tamlihat, Takako Akimoto, Ernita Akmal, Eman Al Qasim, Razi Alalqam, Tanvir Alam, Tala Al-dabbous, Senthilkumar Alegesan, Cynthia Alegre, Marta Alessi, Beatrice Alex, Kévin Alexandre, Abdulrahman Al-Fares, Huda Alfoudri, Imran Ali, Naseem Ali Shah, Kazali Enagnon Alidjnou, Jeffrey Aliudin, Qabas Alkhafajee, Clotilde Allavena, Nathalie Allou, Aneela Altaf, João Alves, João Melo Alves, Rita Alves, Maria Amaral, Nur Amira, Heidi Ammerlaan, Phoebe Ampaw, Roberto Andini, Claire Andrejak, Andrea Angheben, François Angoulvant, Séverine Ansart, Sivanesen Anthonidass, Massimo Antonelli, Carlos Alexandre Antunes de Brito, Kazi Rubayet Anwar, Ardiyan Apriyana, Yaseen Arabi, Irene Aragao, Rajeshwari Arali, Francisco Arancibia, Carolline Araujo, Antonio Arcadipane, Patrick Archambault, Lukas Arenz, Jean-Benoît Arlet, Christel Arnold-Day, Ana Aroca, Lovkesh Arora, Rakesh Arora, Elise Artaud-Macari, Diptesh Aryal, Motohiro Asaki, Angel Asensio, Elizabeth Ashley, Muhammad Ashraf, Sheharyar Ashraf, Mohammad Asim, Jean Baptiste Assie, Amirul Asyraf, Anika Atique, AM Udara Lakshan Attanyake, Johann Auchabie, Hugues Aumaitre, Adrien Auvet, Laurène Azemar, Cecile Azoulay, Benjamin Bach, Delphine Bachelet, Claudine Badr, Nadia Baig, J. 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Barclay, Saef Umar Barnett, Michaela Barnikel, Helena Barrasa, Audrey Barrelet, Cleide Barrigoto, Marie Bartoli, Cheryl Bartone, Joaquín Baruch, Mustehan Bashir, Romain Basmaci, Muhammad Fadhli Hassin Basri, Diego Bastos, Denise Battaglini, Jules Bauer, Diego Fernando Bautista Rincon, Denisse Bazan Dow, Alexandra Bedossa, Ker Hong Bee, Sylvie Behilill, Albertus Beishuizen, Aleksandr Beljantsev, David Bellemare, Anna Beltrame, Beatriz Amorim Beltrão, Marine Beluze, Nicolas Benech, Lionel Eric Benjiman, Dehbia Benkerrou, Suzanne Bennett, Luís Bento, Jan-Erik Berdal, Delphine Bergeaud, Hazel Bergin, José Luis Bernal Sobrino, Giulia Bertoli, Lorenzo Bertolino, Simon Bessis, Adam Betz, Sybille Bevilcaqua, Karine Bezulier, Amar Bhatt, Krishna Bhavsar, Isabella Bianchi, Claudia Bianco, Farah Nadiah Bidin, Moirangthem Bikram Singh, Felwa Bin Humaid, Mohd Nazlin Bin Kamarudin, François Bissuel, Patrick Biston, Laurent Bitker, Pablo Blanco-Schweizer, Catherine Blier, Frank Bloos, Mathieu Blot, Lucille Blumberg, Filomena Boccia, Laetitia Bodenes, Alice Bogaarts, Debby Bogaert, Anne-Hélène Boivin, Pierre-Adrien Bolze, François Bompart, Aurelius Bonfasius, Diogo Borges, Raphaël Borie, Hans Martin Bosse, Elisabeth Botelho-Nevers, Lila Bouadma, Olivier Bouchaud, Sabelline Bouchez, Dounia Bouhmani, Damien Bouhour, Kévin Bouiller, Laurence Bouillet, Camile Bouisse, Anne-Sophie Boureau, John Bourke, Maude Bouscambert, Aurore Bousquet, Jason Bouziotis, Bianca Boxma, Marielle Boyer-Besseyre, Maria Boylan, Fernando Augusto Bozza, Matthew Brack, Axelle Braconnier, Cynthia Braga, Timo Brandenburger, Filipa Brás Monteiro, Luca Brazzi, Dorothy Breen, Patrick Breen, Patrick Breen, Stephen Brett, Kathy Brickell, Tessa Broadley, Alex Browne, Shaunagh Browne, Nicolas Brozzi, Marjolein Brusse-Keizer, Nina Buchtele, Christian Buesaquillo, Polina Bugaeva, Marielle Buisson, Erlina Burhan, Aidan Burrell, Ingrid G. 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    , Sheryl Ann Abdukahil, Ryuzo Abe, Laurent Abel, Lara Absil, Andrew Acker, Shingo Adachi, Elisabeth Adam, Diana Adrião, Kate Ainscough, Ali Ait Hssain, Younes Ait Tamlihat, Takako Akimoto, Tala Al-Dabbous, Abdulrahman Al-Fares, Eman Al Qasim, Razi Alalqam, Beatrice Alex, Kévin Alexandre, Huda Alfoudri, Kazali Enagnon Alidjnou, Jeffrey Aliudin, Clotilde Allavena, Nathalie Allou, João Alves, Rita Alves, Maria Amaral, Heidi Ammerlaan, Phoebe Ampaw, Roberto Andini, Claire Andrejak, Andrea Angheben, François Angoulvant, Séverine Ansart, Massimo Antonelli, Carlos Alexandre Antunes De Brito, Yaseen Arabi, Irene Aragao, Antonio Arcadipane, Lukas Arenz, Jean-Benoît Arlet, Christel Arnold-Day, Lovkesh Arora, Elise Artaud-Macari, Angel Asensio, Jean Baptiste Assie, Anika Atique, Johann Auchabie, Hugues Aumaitre, Laurène Azemar, Cécile Azoulay, Benjamin Bach, Delphine Bachelet, J. Kenneth Baillie, Erica Bak, Agamemnon Bakakos, Firouzé Banisadr, Renata Barbalho, Wendy S. Barclay, Michaela Barnikel, Audrey Barrelet, Cleide Barrigoto, Romain Basmaci, Diego Fernando Bautista Rincon, Alexandra Bedossa, Sylvie Behilill, Aleksandr Beljantsev, David Bellemare, Anna Beltrame, Marine Beluze, Nicolas Benech, Dehbia Benkerrou, Suzanne Bennett, LuÍs Bento, Jan-Erik Berdal, Delphine Bergeaud, Lorenzo Bertolino, Simon Bessis, Sybille Bevilcaqua, Krishna Bhavsar, Felwa Bin Humaid, François Bissuel, Patrick Biston, Laurent Bitker, Pablo Blanco-Schweizer, Mathieu Blot, Filomena Boccia, Debby Bogaert, François Bompart, Gareth Booth, Diogo Borges, Raphaël Borie, Jeannet Bos, Hans Martin Bosse, Elisabeth Botelho-Nevers, Lila Bouadma, Olivier Bouchaud, Sabelline Bouchez, Dounia Bouhmani, Damien Bouhour, Kévin Bouiller, Laurence Bouillet, Camille Bouisse, Anne-Sophie Boureau, Maude Bouscambert, Jason Bouziotis, Bianca Boxma, Marielle Boyer-Besseyre, Maria Boylan, Cynthia Braga, Timo Brandenburger, Luca Brazzi, Dorothy Breen, Patrick Breen, Kathy Brickell, Nicolas Brozzi, Nina Buchtele, Christian Buesaquillo, Polina Bugaeva, Marielle Buisson, Erlina Burhan, Ingrid G. Bustos, Denis Butnaru, Sheila Cárcel, André Cabie, Susana Cabral, Eder Caceres, Mia Callahan, Kate Calligy, Jose Andres Calvache, João Camões, Valentine Campana, Paul Campbell, Cecilia Canepa, Mireia Cantero, Pauline Caraux-Paz, Filipa Cardoso, Filipe Cardoso, Sofia Cardoso, Simone Carelli, Nicolas Carlier, Gayle Carney, Chloe Carpenter, Marie-Christine Carret, François Martin Carrier, Gail Carson, Maire-Laure Casanova, Mariana Cascão, José Casimiro, Bailey Cassandra, Silvia Castañeda, Nidyanara Castanheira, Guylaine Castor-Alexandre, Henry Castrillón, Ivo Castro, Ana Catarino, François-Xavier Catherine, Roberta Cavalin, Giulio Giovanni Cavalli, Alexandros Cavayas, Adrian Ceccato, Minerva Cervantes-Gonzalez, Anissa Chair, Catherine Chakveatze, Adrienne Chan, Meera Chand, Julie Chas, Camille Chassin, Anjellica Chen, Yih-Sharng Chen, Matthew Pellan Cheng, Antoine Cheret, Thibault Chiarabini, Julian Chica, Catherine Chirouze, Davide Chiumello, Hwa Jin Cho, Sung Min Cho, Bernard Cholley, Jose Pedro Cidade, Jose Miguel Cisneros Herreros, Barbara Wanjiru Citarella, Anna Ciullo, Jennifer Clarke, Sara Clohisey, Cassidy Codan, Caitriona Cody, Alexandra Coelho, Gwenhaël Colin, Michael Collins, Sebastiano Maria Colombo, Pamela Combs, J. P. Connelly, Marie Connor, Anne Conrad, Sofía Contreras, Graham S. Cooke, Mary Copland, Hugues Cordel, Amanda Corley, Sarah Cormican, Sabine Cornelis, Arianne Joy Corpuz, Grégory Corvaisier, Camille Couffignal, Sandrine Couffin-Cadiergues, Roxane Courtois, Charles Crepy D’Orleans, Sabine Croonen, Gloria Crowl, Jonathan Crump, Claudina Cruz, Marc Csete, Alberto Cucino, Caroline Cullen, Matthew Cummings, Gerard Curley, Elodie Curlier, Paula Custodio, Frédérick D’Aragon, Ana Da Silva Filipe, Charlene Da Silveira, Eric D’Ortenzio, Al-Awwab Dabaliz, Andrew B. Dagens, Heidi Dalton, Jo Dalton, Nick Daneman, Emmanuelle A. Dankwa, Jorge Dantas, Nathalie De Castro, Diego De Mendoza, Rafael Freitas De Oliveira França, Rosanna De Rosa, Thushan De Silva, Peter De Vries, David Dean, Marie-Pierre Debray, William Dechert, Lauren Deconninck, Romain Decours, Isabelle Delacroix, Karen Delavigne, Ionna Deligiannis, Andrea Dell’amore, Pierre Delobel, Elisa Demonchy, Emmanuelle Denis, Dominique Deplanque, Pieter Depuydt, Mehul Desai, Diane Descamps, Mathilde Desvallée, Santi Rahayu Dewayanti, Alpha Diallo, Sylvain Diamantis, André Dias, Juan Jose Diaz Diaz, Rodrigo Diaz, Kévin Didier, Jean-Luc Diehl, Wim Dieperink, Jérôme Dimet, Vincent Dinot, Alphonsine Diouf, Yael Dishon, Félix Djossou, Annemarie B. Docherty, Andy Dong, Christl A. Donnelly, Maria Donnelly, Chloe Donohue, Céline Dorival, James Joshua Douglas, Renee Douma, Nathalie Dournon, Triona Downer, Mark Downing, Tom Drake, Vincent Dubee, François Dubos, Alexandra Ducancelle, Susanne Dudman, Jake Dunning, Emanuele Durante Mangoni, Silvia Duranti, Lucian Durham, Bertrand Dussol, Xavier Duval, Anne Margarita Dyrhol-Riise, Carla Eira, José Ernesto Vidal, Mohammed El Sanharawi, Subbarao Elapavaluru, Brigitte Elharrar, Natalie Elkheir, Jacobien Ellerbroek, Rachael Ellis, Philippine Eloy, Tarek Elshazly, Isabelle Enderle, Ilka Engelmann, Vincent Enouf, Olivier Epaulard, Mariano Esperatti, Hélène Esperou, Marina Esposito-Farese, João Estevão, Manuel Etienne, Manuel Etienne, Nadia Ettalhaoui, Anna Greti Everding, Mirjam Evers, Isabelle Fabre, Amna Faheem, Arabella Fahy, Cameron J. Fairfield, Pedro Faria, Nataly Farshait, Arie Zainul Fatoni, Karine Faure, Mohamed Fayed, Niamh Feely, Jorge Fernandes, Marília Fernandes, Susana Fernandes, Joana Ferrão, Eglantine Ferrand Devouge, Mário Ferraz, Benigno Ferreira, Ricard Ferrer-Roca, Claudia Figueiredo-Mello, Clara Flateau, Tom Fletcher, Letizia Lucia Florio, Claire Foley, Victor Fomin, Claudio Duarte Fonseca, Tatiana Fonseca, Patricia Fontela, Simon Forsyth, Giuseppe Foti, Erwan Fourn, Rob Fowler, Diego Franch-Llasat, Christophe Fraser, John Fraser, Marcela Vieira Freire, Ana Freitas Ribeiro, Caren Friedrich, Stéphane Fry, Nora Fuentes, Masahiro Fukuda, Joan Gómez-Junyent, Valérie Gaborieau, Benoît Gachet, Rostane Gaci, Massimo Gagliardi, Jean-Charles Gagnard, Amandine Gagneux-Brunon, Sérgio Gaião, Phil Gallagher, Elena Gallego Curto, Carrol Gamble, Arthur Garan, Esteban Garcia-Gallo, Rebekha Garcia, Denis Garot, Valérie Garrait, Nathalie Gault, Aisling Gavin, Alexandre Gaymard, Johannes Gebauer, Louis Gerbaud Morlaes, Nuno Germano, Jade Ghosn, Marco Giani, Carlo Giaquinto, Jess Gibson, Tristan Gigante, Morgane Gilg, Guillermo Giordano, Michelle Girvan, Valérie Gissot, Gezy Giwangkancana, Daniel Glikman, Petr Glybochko, Eric Gnall, Geraldine Goco, François Goehringer, Siri Goepel, Jean-Christophe Goffard, Jonathan Golob, Isabelle Gorenne, Cécile Goujard, Tiphaine Goulenok, Margarite Grable, Edward Wilson Grandin, Pascal Granier, Giacomo Grasselli, Christopher A. Green, William Greenhalf, Segolène Greffe, Domenico Luca Grieco, Matthew Griffee, Fiona Griffiths, Ioana Grigoras, Albert Groenendijk, Anja Grosse Lordemann, Heidi Gruner, Yusing Gu, Jérémie Guedj, Dewi Guellec, Anne-Marie Guerguerian, Daniela Guerreiro, Romain Guery, Anne Guillaumot, Laurent Guilleminault, Thomas Guimard, Daniel Haber, Sheeba Hakak, Matthew Hall, Sophie Halpin, Ansley Hamer, Rebecca Hamidfar, Terese Hammond, Hayley Hardwick, Kristen Harley, Ewen M. Harrison, Janet Harrison, Leanne Hays, Jan Heerman, Lars Heggelund, Ross Hendry, Martina Hennessy, Aquiles Henriquez-Trujillo, Maxime Hentzien, Jaime Hernandez-Montfort, Astarini Hidayah, Dawn Higgins, Eibhilin Higgins, Samuel Hinton, Ana Hipólito-Reis, Hiroaki Hiraiwa, Julian A. Hiscox, Antonia Ying Wai Ho, Alexandre Hoctin, Isabelle Hoffmann, Oscar Hoiting, Rebecca Holt, Jan Cato Holter, Peter Horby, Juan Pablo Horcajada, Koji Hoshino, Kota Hoshino, Catherine L. Hough, Jimmy Ming-Yang Hsu, Jean-Sébastien Hulot, Samreen Ijaz, Hajnal-Gabriela Illes, Hugo Inácio, Carmen Infante Dominguez, Elias Iosifidis, Lacey Irvine, Sarah Isgett, Tiago Isidoro, Margaux Isnard, Junji Itai, Daniel Ivulich, Salma Jaafoura, Julien Jabot, Clare Jackson, Nina Jamieson, Stéphane Jaureguiberry, Jeffrey Javidfar, Zabbe Jean-Benoît, Florence Jego, Synne Jenum, Ruth Jimbo Sotomayor, Ruth Noemí Jorge GarcÍa, Cédric Joseph, Mark Joseph, Philippe Jouvet, Hanna Jung, Ouifiya Kafif, Florentia Kaguelidou, Sabina Kali, Smaragdi Kalomoiri, Darshana Hewa Kandamby, Chris Kandel, Ravi Kant, Christiana Kartsonaki, Daisuke Kasugai, Kevin Katz, Simreen Kaur Johal, Sean Keating, Andrea Kelly, Sadie Kelly, Lisa Kennedy, Kalynn Kennon, Younes Kerroumi, Evelyne Kestelyn, Imrana Khalid, Antoine Khalil, Coralie Khan, Irfan Khan, Michelle E. Kho, Saye Khoo, Yuri Kida, Peter Kiiza, Anders Benjamin Kildal, Antoine Kimmoun, Detlef Kindgen-Milles, Nobuya Kitamura, Paul Klenerman, Gry Kloumann Bekken, Stephen Knight, Robin Kobbe, Malte Kohns Vasconcelos, Volkan Korten, Caroline Kosgei, Karolina Krawczyk, Pavan Kumar Vecham, Deepali Kumar, Ethan Kurtzman, Demetrios Kutsogiannis, Konstantinos Kyriakoulis, Erwan L’her, Marie Lachatre, Marie Lacoste, John G. Laffey, Marie Lagrange, Fabrice Laine, Marc Lambert, François Lamontagne, Marie Langelot-Richard, Eka Yudha Lantang, Marina Lanza, Cédric Laouénan, Samira Laribi, Delphine Lariviere, Odile Launay, Yoan Lavie-Badie, Andrew Law, Clément Le Bihan, Cyril Le Bris, Eve Le Coustumier, Georges Le Falher, Sylvie Le Gac, Quentin Le Hingrat, Marion Le Maréchal, Soizic Le Mestre, Vincent Le Moing, Hervé Le Nagard, Paul Le Turnier, Rafael León, Minh Le, Marta Leal Santos, Ema Leal, James Lee, Su Hwan Lee, Todd Lee, Gary Leeming, Bénédicte Lefebvre, Laurent Lefebvre, Benjamin Lefevre, François Lellouche, Adrien Lemaignen, Véronique Lemee, Gretchen Lemmink, Michela Leone, Quentin Lepiller, François-Xavier Lescure, Olivier Lesens, Mathieu Lesouhaitier, Claire Levy-Marchal, Bruno Levy, Yves Levy, Gianluigi Li Bassi, Janet Liang, Wei Shen Lim, Bruno Lina, Andreas Lind, Guillaume Lingas, Sylvie Lion-Daolio, Keibun Liu, Antonio Loforte, Navy Lolong, Diogo Lopes, Dalia Lopez-Colon, Paul Loubet, Jean Christophe Lucet, Carlos M. Luna, Olguta Lungu, Liem Luong, Dominique Luton, Ruth Lyons, Fredrik Müller, Karl Erik Müller, Olavi Maasikas, Sarah Macdonald, Moïse Machado, Gabrielle Macheda, Juan Macias Sanchez, Jai Madhok, Rafael Mahieu, Sophie Mahy, Lars Siegfrid Maier, Mylène Maillet, Thomas Maitre, Maximilian Malfertheiner, Nadia Malik, Fernando Maltez, Denis Malvy, Marina Mambert, Victoria Manda, Jose M. Mandei, Edmund Manning, Aldric Manuel, Ceila Maria Sant, Ana Malaque, Flávio Marino, Carolline De Araújo Mariz, Charbel Maroun Eid, Ana Marques, Catherine Marquis, Brian Marsh, Laura Marsh, John Marshall, Celina Turchi Martelli, Guillaume Martin-Blondel, Ignacio Martin-Loeches, Alejandro Martin-Quiros, Dori-Ann Martin, Emily Martin, Martin Martinot, Caroline Martins Rego, Ana Martins, João Martins, Gennaro Martucci, Eva Miranda Marwali, Juan Fernado Masa Jimenez, David Maslove, Sabina Mason, Moshe Matan, Daniel Mathieu, Mathieu Mattei, Romans Matulevics, Laurence Maulin, Natalie Mc Evoy, Aine McCarthy, Colin McCloskey, Rachael McConnochie, Sherry McDermott, Sarah McDonald, Samuel McElwee, Natalie McEvoy, Allison McGeer, Niki McGuinness, Kenneth A. McLean, Bairbre McNicholas, Edel Meaney, Cécile Mear-Passard, Maggie Mechlin, Ferruccio Mele, Kusum Menon, France Mentré, Alexander J. 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Nunez, Elsa Nyamankolly, Max O’Donnell, Katie O’Hearn, Conar O’Neil, Giovanna Occhipinti, Tawnya Ogston, Takayuki Ogura, Tak-Hyuk Oh, Shinichiro Ohshimo, Budha Charan Singh Oinam, Ana Pinho Oliveira, João Oliveira, Piero Olliaro, David S. Y. Ong, Wilna Oosthuyzen, Peter J. M. Openshaw, Claudia Milena Orozco-Chamorro, Andrés Orquera, Javier Osatnik, Nadia Ouamara, Rachida Ouissa, Clark Owyang, Eric Oziol, Diana Póvoas, Maïder Pagadoy, Justine Pages, Mario Palacios, Massimo Palmarini, Giovanna Panarello, Prasan Kumar Panda, Mauro Panigada, Nathalie Pansu, Aurélie Papadopoulos, Briseida Parra, Jérémie Pasquier, Fabian Patauner, Luís Patrão, Christelle Paul, Mical Paul, Jorge Paulos, William A. Paxton, Jean-François Payen, India Pearse, Giles J. Peek, Florent Peelman, Nathan Peiffer-Smadja, Vincent Peigne, Mare Pejkovska, Ithan D. 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Svistunov, Konstantinos Syrigos, Jaques Sztajnbok, Konstanty Szuldrzynski, François Téoulé, Shirin Tabrizi, Lysa Tagherset, Ewa Talarek, Sara Taleb, Jelmer Talsma, Tan Le Van, Hiroyuki Tanaka, Taku Tanaka, Hayato Taniguchi, Coralie Tardivon, Pierre Tattevin, M. Azhari Taufik, Richard S. Tedder, João Teixeira, Marie-Capucine Tellier, Pleun Terpstra, Olivier Terrier, Nicolas Terzi, Hubert Tessier-Grenier, Vincent Thibault, Simon-Djamel Thiberville, Benoît Thill, A. A. Roger Thompson, Shaun Thompson, David Thomson, Emma C. Thomson, Duong Bich Thuy, Ryan S. Thwaites, Peter S. Timashev, Jean-François Timsit, Bharath Kumar Tirupakuzhi Vijayaraghavan, Maria Toki, Kristian Tonby, Rosario Maria Torres Santos-Olmo, Antoni Torres, Margarida Torres, Théo Trioux, Huynh Trung Trieu, Cécile Tromeur, Ioannis Trontzas, Jonathan Troost, Tiffany Trouillon, Christelle Tual, Sarah Tubiana, Helen Tuite, Lance C. W. 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    Lancet Regional Health Europe, 2021
  • X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19
    Takaki Asano, Bertrand Boisson, Fanny Onodi, Daniela Matuozzo, Marcela Moncada-Velez, Majistor Raj Luxman Maglorius Renkilaraj, Peng Zhang, Laurent Meertens, Alexandre Bolze, Marie Materna, Sarantis Korniotis, Adrian Gervais, Estelle Talouarn, Benedetta Bigio, Yoann Seeleuthner, Kaya Bilguvar, Yu Zhang, Anna-Lena Neehus, Masato Ogishi, Simon J. Pelham, Tom Le Voyer, Jérémie Rosain, Quentin Philippot, Pere Soler-Palacín, Roger Colobran, Andrea Martin-Nalda, Jacques G. Rivière, Yacine Tandjaoui-Lambiotte, Khalil Chaïbi, Mohammad Shahrooei, Ilad Alavi Darazam, Nasrin Alipour Olyaei, Davood Mansouri, Nevin Hatipoğlu, Figen Palabiyik, Tayfun Ozcelik, Giuseppe Novelli, Antonio Novelli, Giorgio Casari, Alessandro Aiuti, Paola Carrera, Simone Bondesan, Federica Barzaghi, Patrizia Rovere-Querini, Cristina Tresoldi, Jose Luis Franco, Julian Rojas, Luis Felipe Reyes, Ingrid G. 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Tuinman, Marc van der Valk, Denise Veelo, Carolien Volleman, Heder de Vries, Lonneke A. Vught, Michèle van Vugt, Dorien Wouters, A. H (Koos) Zwinderman, Matthijs C. Brouwer, W. Joost Wiersinga, Alexander P.J. Vlaar, Diederik van de Beek, Miranda F. Tompkins, Camille Alba, Andrew L. Snow, Daniel N. Hupalo, John Rosenberger, Gauthaman Sukumar, Matthew D. Wilkerson, Xijun Zhang, Justin Lack, Andrew J. Oler, Kerry Dobbs, Ottavia M. Delmonte, Jeffrey J. Danielson, Andrea Biondi, Laura Rachele Bettini, Mariella D’Angio, Ilaria Beretta, Luisa Imberti, Alessandra Sottini, Virginia Quaresima, Eugenia Quiros-Roldan, Camillo Rossi, , , , , , , , and
    Science Immunology, 2021
  • Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
    Paul Bastard, Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot, Jérémy Manry, Eleftherios Michailidis, Hans-Heinrich Hoffmann, Shohei Eto, Marina Garcia-Prat, Lucy Bizien, Alba Parra-Martínez, Rui Yang, Liis Haljasmägi, Mélanie Migaud, Karita Särekannu, Julia Maslovskaja, Nicolas de Prost, Yacine Tandjaoui-Lambiotte, Charles-Edouard Luyt, Blanca Amador-Borrero, Alexandre Gaudet, Julien Poissy, Pascal Morel, Pascale Richard, Fabrice Cognasse, Jesus Troya, Sophie Trouillet-Assant, Alexandre Belot, Kahina Saker, Pierre Garçon, Jacques G. Rivière, Jean-Christophe Lagier, Stéphanie Gentile, Lindsey B. Rosen, Elana Shaw, Tomohiro Morio, Junko Tanaka, David Dalmau, Pierre-Louis Tharaux, Damien Sene, Alain Stepanian, Bruno Megarbane, Vasiliki Triantafyllia, Arnaud Fekkar, James R. Heath, José Luis Franco, Juan-Manuel Anaya, Jordi Solé-Violán, Luisa Imberti, Andrea Biondi, Paolo Bonfanti, Riccardo Castagnoli, Ottavia M. Delmonte, Yu Zhang, Andrew L. Snow, Steven M. Holland, Catherine M. Biggs, Marcela Moncada-Vélez, Andrés Augusto Arias, Lazaro Lorenzo, Soraya Boucherit, Boubacar Coulibaly, Dany Anglicheau, Anna M. Planas, Filomeen Haerynck, Sotirija Duvlis, Robert L. Nussbaum, Tayfun Ozcelik, Sevgi Keles, Ahmed A. Bousfiha, Jalila El Bakkouri, Carolina Ramirez-Santana, Stéphane Paul, Qiang Pan-Hammarström, Lennart Hammarström, Annabelle Dupont, Alina Kurolap, Christine N. Metz, Alessandro Aiuti, Giorgio Casari, Vito Lampasona, Fabio Ciceri, Lucila A. Barreiros, Elena Dominguez-Garrido, Mateus Vidigal, Mayana Zatz, Diederik van de Beek, Sabina Sahanic, Ivan Tancevski, Yurii Stepanovskyy, Oksana Boyarchuk, Yoko Nukui, Miyuki Tsumura, Loreto Vidaur, Stuart G. Tangye, Sonia Burrel, Darragh Duffy, Lluis Quintana-Murci, Adam Klocperk, Nelli Y. Kann, Anna Shcherbina, Yu-Lung Lau, Daniel Leung, Matthieu Coulongeat, Julien Marlet, Rutger Koning, Luis Felipe Reyes, Angélique Chauvineau-Grenier, Fabienne Venet, Guillaume Monneret, Michel C. Nussenzweig, Romain Arrestier, Idris Boudhabhay, Hagit Baris-Feldman, David Hagin, Joost Wauters, Isabelle Meyts, Adam H. Dyer, Sean P. Kennelly, Nollaig M. Bourke, Rabih Halwani, Narjes Saheb Sharif-Askari, Karim Dorgham, Jérome Sallette, Souad Mehlal Sedkaoui, Suzan AlKhater, Raúl Rigo-Bonnin, Francisco Morandeira, Lucie Roussel, Donald C. Vinh, Sisse Rye Ostrowski, Antonio Condino-Neto, Carolina Prando, Anastasiia Bondarenko, András N. Spaan, Laurent Gilardin, Jacques Fellay, Stanislas Lyonnet, Kaya Bilguvar, Richard P. Lifton, Shrikant Mane, Mark S. Anderson, Bertrand Boisson, Vivien Béziat, Shen-Ying Zhang, Evangelos Andreakos, Olivier Hermine, Aurora Pujol, Pärt Peterson, Trine H. Mogensen, Lee Rowen, James Mond, Stéphanie Debette, Xavier de Lamballerie, Xavier Duval, France Mentré, Marie Zins, Pere Soler-Palacin, Roger Colobran, Guy Gorochov, Xavier Solanich, Sophie Susen, Javier Martinez-Picado, Didier Raoult, Marc Vasse, Peter K. Gregersen, Lorenzo Piemonti, Carlos Rodríguez-Gallego, Luigi D. Notarangelo, Helen C. Su, Kai Kisand, Satoshi Okada, Anne Puel, Emmanuelle Jouanguy, Charles M. Rice, Pierre Tiberghien, Qian Zhang, Aurélie Cobat, Laurent Abel, Jean-Laurent Casanova, , , , , , , , , , , , , , , , , , and
    Science Immunology, 2021
  • Early nasal type I IFN immunity against SARS-CoV-2 is compromised in patients with autoantibodies against type I IFNs
    Jonathan Lopez, Marine Mommert, William Mouton, Andrés Pizzorno, Karen Brengel-Pesce, Mehdi Mezidi, Marine Villard, Bruno Lina, Jean-Christophe Richard, Jean-Baptiste Fassier, Valérie Cheynet, Blandine Padey, Victoria Duliere, Thomas Julien, Stéphane Paul, Paul Bastard, Alexandre Belot, Antonin Bal, Jean-Laurent Casanova, Manuel Rosa-Calatrava, Florence Morfin, Thierry Walzer, Sophie Trouillet-Assant
    Journal of Experimental Medicine, 2021
  • Characteristics of the delayed respiratory syncytial virus epidemic, 2020/2021, Rhône Loire, France
    Jean-Sebastien Casalegno, Dominique Ploin, Aymeric Cantais, Elsa Masson, Emilie Bard, Martine Valette, Remi Fanget, Sandrine Couray Targe, Anne-Florence Myar-Dury, Muriel Doret-Dion, Mona Massoud, Gregory Queromes, Philippe Vanhems, Olivier Claris, Marine Butin, Sylvie Pillet, Florence Ader, Sylvie Bin, Alexandre Gaymard, Bruno Lina, Florence Morfin, Etienne Javouhey, Yves Gillet, and
    Eurosurveillance, 2021
  • Detection of SARS-CoV-2 N-antigen in blood during acute COVID-19 provides a sensitive new marker and new testing alternatives
    Quentin Le Hingrat, Benoit Visseaux, Cedric Laouenan, Sarah Tubiana, Lila Bouadma, Yazdan Yazdanpanah, Xavier Duval, Charles Burdet, Houria Ichou, Florence Damond, Melanie Bertine, Nabil Benmalek, Christophe Choquet, Jean-Francois Timsit, Jade Ghosn, Charlotte Charpentier, Diane Descamps, Nadhira Houhou-Fidouh, Alpha Diallo, Soizic Le Mestre, Noemie Mercier, Christelle Paul, Ventzislava Petrov-Sanchez, Denis Malvy, Catherine Chirouze, Claire Andrejak, Francois Dubos, Patrick Rossignol, Olivier Picone, Francois Bompart, Tristan Gigante, Morgane Gilg, Benedicte Rossignol, Claire Levy-Marchal, Marine Beluze, Jean Sebastien Hulot, Delphine Bachelet, Krishna Bhavsar, Lila Bouadma, Anissa Chair, Camille Couffignal, Charlene Da Silveira, Marie Pierre Debray, Diane Descamps, Xavier Duval, Philippine Eloy, Marina Esposito-Farese, Nadia Ettalhaoui, Nathalie Gault, Jade Ghosn, Isabelle Gorenne, Isabelle Hoffmann, Ouifiya Kafif, Sabrina Kali, Antoine Khalil, Cedric Laouenan, Samira Laribi, Minh Le, Quentin Le Hingrat, Francois-Xavier Lescure, Jean Christophe Lucet, France Mentre, Jimmy Mullaert, Nathan Peiffer-Smadja, Gilles Peytavin, Carine Roy, Marion Schneider, Nassima Si Mohammed, Lysa Tagherset, Coralie Tardivon, Marie Capucine Tellier, Jean-Francois Timsit, Theo Trioux, Sarah Tubiana, Benoit Visseaux, Noemie Vanel, Romain Basmaci, Francois Angoulvant, Florentia Kaguelidou, Justine Pages, Christelle Tual, Aurelie Veislinger, Sandrine Couffin-Cardiergues, Helene Esperou, Ikram Houas, Salma Jaafoura, Aurelie Papadopoulos, Alexandra Coelho, Alphonsine Diouf, Alexandre Hoctin, Marina Mambert, Maude Bouscambert, Alexandre Gaymard, Bruno Lina, Manuel Rosa-Calatrava, Olivier Terrier, Dehbia Benkerrou, Celine Dorival, Amina Meziane, Francois Teoule, Jeremie Guedj, Herve Le Nagard, Guillaume Lingas, Nadege Neant, Laurent Abel, Mathilde Desvallee, Coralie Khan, Dominique Deplanque, Yazdan Yazdanpanah, Sylvie Behilill, Vincent Enouf, Hugo Mouquet, Sylvie Van Der Werf, Minerva Cervantes-Gonzalez, Eric D'ortenzio, Oriane Puechal, Caroline Semaille, Marion Noret, Manuel Etienne, Yves Levy, Aurelie Wiedemann
    Clinical Microbiology and Infection, 2021
  • Type-I Interferon assessment in 45 minutes using the FilmArray® PCR platform in SARS-CoV-2 and other viral infections
    Marine Mommert, M. Perret, Matthew Hockin, S. Viel, A. Belot, J. Richard, M. Mezidi, J. Fassier, E. Javouhey, A. Hemmert, François Mallet, S. Trouillet-Assant, K. Brengel-Pesce
    European Journal of Immunology, 2021
  • Early assessment of diffusion and possible expansion of SARS-CoV-2 Lineage 20I/501Y.V1 (B.1.1.7, variant of concern 202012/01) in France, January to March 2021
    Alexandre Gaymard, Paolo Bosetti, Adeline Feri, Gregory Destras, Vincent Enouf, Alessio Andronico, Sonia Burrel, Sylvie Behillil, Claire Sauvage, Antonin Bal, Florence Morfin, Sylvie Van Der Werf, Laurence Josset, François Blanquart, Bruno Coignard, Simon Cauchemez, Bruno Lina, , and
    Eurosurveillance, 2021
  • Modeling SARS-CoV-2 viral kinetics and association with mortality in hospitalized patients from the French COVID cohort
    Nadège Néant, Guillaume Lingas, Quentin Le Hingrat, Jade Ghosn, Ilka Engelmann, Quentin Lepiller, Alexandre Gaymard, Virginie Ferré, Cédric Hartard, Jean-Christophe Plantier, Vincent Thibault, Julien Marlet, Brigitte Montes, Kevin Bouiller, François-Xavier Lescure, Jean-François Timsit, Emmanuel Faure, Julien Poissy, Christian Chidiac, François Raffi, Antoine Kimmoun, Manuel Etienne, Jean-Christophe Richard, Pierre Tattevin, Denis Garot, Vincent Le Moing, Delphine Bachelet, Coralie Tardivon, Xavier Duval, Yazdan Yazdanpanah, France Mentré, Cédric Laouénan, Benoit Visseaux, Jérémie Guedj, and
    Proceedings of the National Academy of Sciences of the United States of America, 2021
  • Chest CT for rapid triage of patients in multiple emergency departments during COVID-19 epidemic: experience report from a large French university hospital
    Victoria Ducray, , Anna Sesilia Vlachomitrou, Maude Bouscambert-Duchamp, Salim Si-Mohamed, Sylvain Gouttard, Adeline Mansuy, Florian Wickert, Alain Sigal, Alexandre Gaymard, François Talbot, Catherine Michel, Thomas Perpoint, Jean-Baptiste Pialat, Olivier Rouviere, Laurent Milot, François Cotton, Philippe Douek, Muriel Rabilloud, Loic Boussel
    European Radiology, 2021
  • Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69–V70, France, August to December 2020
    A. Bal, G. Destras, A. Gaymard, K. Stefic, J. Marlet, S. Eymieux, H. Regue, Q. Semanas, Constance d'Aubarede, G. Billaud, F. Laurent, C. González, Y. Mekki, M. Valette, M. Bouscambert, C. Gaudy-Graffin, B. Lina, F. Morfin, L. Josset
    Eurosurveillance, 2021
  • Factors associated with admission to intensive care units in COVID-19 patients in Lyon-France
    Philippe Vanhems, Marie-Paule Gustin, Christelle Elias, Laetitia Henaff, Cédric Dananché, Béatrice Grisi, Elodie Marion, Nagham Khanafer, Delphine Hilliquin, Sophie Gardes, Solweig Gerbier-Colomban, Selilah Amour, Elisabetta Kuczewski, Vanessa Escuret, Bruno Lina, Mitra Saadatian-Elahi, and
    Plos One, 2021
  • Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort
    ISARIC Clinical Characterisation Group, Matthew D Hall, Joaquín Baruch, Gail Carson, Barbara Wanjiru Citarella, Andrew Dagens, Emmanuelle A Dankwa, Christl A Donnelly, Jake Dunning, Martina Escher, Christiana Kartsonaki, Laura Merson, Mark Pritchard, Jia Wei, Peter W Horby, Amanda Rojek, Piero L Olliaro
    Elife, 2021
  • Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
    Qian Zhang, Paul Bastard, Zhiyong Liu, Jérémie Le Pen, Marcela Moncada-Velez, Jie Chen, Masato Ogishi, Ira K. D. Sabli, Stephanie Hodeib, Cecilia Korol, Jérémie Rosain, Kaya Bilguvar, Junqiang Ye, Alexandre Bolze, Benedetta Bigio, Rui Yang, Andrés Augusto Arias, Qinhua Zhou, Yu Zhang, Fanny Onodi, Sarantis Korniotis, Léa Karpf, Quentin Philippot, Marwa Chbihi, Lucie Bonnet-Madin, Karim Dorgham, Nikaïa Smith, William M. Schneider, Brandon S. Razooky, Hans-Heinrich Hoffmann, Eleftherios Michailidis, Leen Moens, Ji Eun Han, Lazaro Lorenzo, Lucy Bizien, Philip Meade, Anna-Lena Neehus, Aileen Camille Ugurbil, Aurélien Corneau, Gaspard Kerner, Peng Zhang, Franck Rapaport, Yoann Seeleuthner, Jeremy Manry, Cecile Masson, Yohann Schmitt, Agatha Schlüter, Tom Le Voyer, Taushif Khan, Juan Li, Jacques Fellay, Lucie Roussel, Mohammad Shahrooei, Mohammed F. Alosaimi, Davood Mansouri, Haya Al-Saud, Fahd Al-Mulla, Feras Almourfi, Saleh Zaid Al-Muhsen, Fahad Alsohime, Saeed Al Turki, Rana Hasanato, Diederik van de Beek, Andrea Biondi, Laura Rachele Bettini, Mariella D’Angio’, Paolo Bonfanti, Luisa Imberti, Alessandra Sottini, Simone Paghera, Eugenia Quiros-Roldan, Camillo Rossi, Andrew J. Oler, Miranda F. Tompkins, Camille Alba, Isabelle Vandernoot, Jean-Christophe Goffard, Guillaume Smits, Isabelle Migeotte, Filomeen Haerynck, Pere Soler-Palacin, Andrea Martin-Nalda, Roger Colobran, Pierre-Emmanuel Morange, Sevgi Keles, Fatma Çölkesen, Tayfun Ozcelik, Kadriye Kart Yasar, Sevtap Senoglu, Şemsi Nur Karabela, Carlos Rodríguez-Gallego, Giuseppe Novelli, Sami Hraiech, Yacine Tandjaoui-Lambiotte, Xavier Duval, Cédric Laouénan, Andrew L. Snow, Clifton L. Dalgard, Joshua D. Milner, Donald C. Vinh, Trine H. Mogensen, Nico Marr, András N. Spaan, Bertrand Boisson, Stéphanie Boisson-Dupuis, Jacinta Bustamante, Anne Puel, Michael J. Ciancanelli, Isabelle Meyts, Tom Maniatis, Vassili Soumelis, Ali Amara, Michel Nussenzweig, Adolfo García-Sastre, Florian Krammer, Aurora Pujol, Darragh Duffy, Richard P. Lifton, Shen-Ying Zhang, Guy Gorochov, Vivien Béziat, Emmanuelle Jouanguy, Vanessa Sancho-Shimizu, Charles M. Rice, Laurent Abel, Luigi D. Notarangelo, Aurélie Cobat, Helen C. Su, Jean-Laurent Casanova, , , , , , , , and
    Science, 2020
  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19
    Paul Bastard, Lindsey B. Rosen, Qian Zhang, Eleftherios Michailidis, Hans-Heinrich Hoffmann, Yu Zhang, Karim Dorgham, Quentin Philippot, Jérémie Rosain, Vivien Béziat, Jérémy Manry, Elana Shaw, Liis Haljasmägi, Pärt Peterson, Lazaro Lorenzo, Lucy Bizien, Sophie Trouillet-Assant, Kerry Dobbs, Adriana Almeida de Jesus, Alexandre Belot, Anne Kallaste, Emilie Catherinot, Yacine Tandjaoui-Lambiotte, Jeremie Le Pen, Gaspard Kerner, Benedetta Bigio, Yoann Seeleuthner, Rui Yang, Alexandre Bolze, András N. Spaan, Ottavia M. Delmonte, Michael S. Abers, Alessandro Aiuti, Giorgio Casari, Vito Lampasona, Lorenzo Piemonti, Fabio Ciceri, Kaya Bilguvar, Richard P. Lifton, Marc Vasse, David M. Smadja, Mélanie Migaud, Jérome Hadjadj, Benjamin Terrier, Darragh Duffy, Lluis Quintana-Murci, Diederik van de Beek, Lucie Roussel, Donald C. Vinh, Stuart G. Tangye, Filomeen Haerynck, David Dalmau, Javier Martinez-Picado, Petter Brodin, Michel C. Nussenzweig, Stéphanie Boisson-Dupuis, Carlos Rodríguez-Gallego, Guillaume Vogt, Trine H. Mogensen, Andrew J. Oler, Jingwen Gu, Peter D. Burbelo, Jeffrey I. Cohen, Andrea Biondi, Laura Rachele Bettini, Mariella D'Angio, Paolo Bonfanti, Patrick Rossignol, Julien Mayaux, Frédéric Rieux-Laucat, Eystein S. Husebye, Francesca Fusco, Matilde Valeria Ursini, Luisa Imberti, Alessandra Sottini, Simone Paghera, Eugenia Quiros-Roldan, Camillo Rossi, Riccardo Castagnoli, Daniela Montagna, Amelia Licari, Gian Luigi Marseglia, Xavier Duval, Jade Ghosn, John S. Tsang, Raphaela Goldbach-Mansky, Kai Kisand, Michail S. Lionakis, Anne Puel, Shen-Ying Zhang, Steven M. Holland, Guy Gorochov, Emmanuelle Jouanguy, Charles M. Rice, Aurélie Cobat, Luigi D. Notarangelo, Laurent Abel, Helen C. Su, Jean-Laurent Casanova, , , , , , , , , , and
    Science, 2020
  • Cluster of coronavirus disease 2019 (COVID-19) in the French Alps, February 2020
    Kostas Danis, Olivier Epaulard, Thomas Bénet, Alexandre Gaymard, Séphora Campoy, Elisabeth Botelho-Nevers, Maude Bouscambert-Duchamp, Guillaume Spaccaferri, Florence Ader, Alexandra Mailles, Zoubida Boudalaa, Violaine Tolsma, Julien Berra, Sophie Vaux, Emmanuel Forestier, Caroline Landelle, Erica Fougere, Alexandra Thabuis, Philippe Berthelot, Raphael Veil, Daniel Levy-Bruhl, Christian Chidiac, Bruno Lina, Bruno Coignard, Christine Saura, Elise Brottet, Delphine Casamatta, Yves Gallien, Scarlett George, Delphine Viriot, Fatima Ait Belghiti, Sibylle Bernard-Stoecklin, Jean-Claude Desenclos, Coralie Giese, Didier Ghislain, Magali Gounon, Nathalie Grangeret, Cécile Marie, Bruno Morel, Muriel Deher, Anne-Sophie Ronnaux Baron, Geneviève Courbis, Nathalie Ragozin, Monika Wolska, Eric Serange, Delphine Mercatello, Soraya Aiouaz, Martine Valette, Emilie Frobert, Laurence Josset, Vanessa Escuret, Florence Morfin, Geneviève Billaud, Myriam Blanc, Julie Arata-Bardet, Marie Froidure, Marion Le Maréchal, Patricia Pavese, Isabelle Pierre, Agathe Becker, Pierre Chauvelot, Anne Conrad, Tristan Ferry, Patrick Miailhes, Thomas Perpoint, Cécile Pouderoux, Sandrine Roux, Florent Valour, Marie-France Lutz, Anne Pouvaret, Virginie Vitrat, Mylène Maillet, Cécile Janssen, Emilie Piet, Alexie Bosch, Anne-Laure Destrem, Margaux Isnard, Thibault Challan-Belval, Chloe Wackenheim, Alice Couturier, Gael Gheno, Thierry Roupioz, Nicolas Lucet, Stéphane Ayouni, Mireille Vincent, Servicio de Epidemiología, Dirección General de Salud Pública del Gover Balear, Virginie Masserey Spicher, Catherine Bourquin, Jeanine Stoll, Pascal Chaud, Anne-Laure Mounayar, and
    Clinical Infectious Diseases, 2020
  • Characterization and Treatment of SARS-CoV-2 in Nasal and Bronchial Human Airway Epithelia
    Andrés Pizzorno, Blandine Padey, Thomas Julien, Sophie Trouillet-Assant, Aurélien Traversier, Elisabeth Errazuriz-Cerda, Julien Fouret, Julia Dubois, Alexandre Gaymard, François-Xavier Lescure, Victoria Dulière, Pauline Brun, Samuel Constant, Julien Poissy, Bruno Lina, Yazdan Yazdanpanah, Olivier Terrier, Manuel Rosa-Calatrava
    Cell Reports Medicine, 2020
  • Molecular characterization of SARS-CoV-2 in the first COVID-19 cluster in France reveals an amino acid deletion in nsp2 (Asp268del)
    A. Bal, G. Destras, A. Gaymard, M. Bouscambert-Duchamp, M. Valette, V. Escuret, E. Frobert, G. Billaud, S. Trouillet-Assant, V. Cheynet, K. Brengel-Pesce, F. Morfin, B. Lina, L. Josset
    Clinical Microbiology and Infection, 2020
  • Type I IFN immunoprofiling in COVID-19 patients
    Sophie Trouillet-Assant, Sebastien Viel, Alexandre Gaymard, Sylvie Pons, Jean-Christophe Richard, Magali Perret, Marine Villard, Karen Brengel-Pesce, Bruno Lina, Mehdi Mezidi, Laurent Bitker, Alexandre Belot, William Mouton, Guy Oriol, Christelle Compagnon, Laurence Generenaz, Valérie Cheynet, Florence Ader, Agathe Becker, Nicholas Benech, Pierre Chauvelot, Christian Chidiac, Anne Conrad, Tristan Ferry, Patrick Miailhes, Thomas Perpoint, Marielle Perry, Cécile Pouderoux, Sandrine Roux, Claire Triffault-Fillit, Florent Valour, Yonis Hodane, Louis Chauvelot, Paul Chabert, Judith Provoost, Guillaume David, Laure Folliet, Pierre Lecam, Geneviève Billaud, Maude Bouscambert, Vanessa Escuret, Emilie Frobert, Antonin Bal, Grégory Destras, Laurence Josset, Florence Morfin, Clément Munier, Martine Valette, Fabienne Venet, Lorna Garnier, Rémi Pescarmona, Christine Lombard, Thierry Walzer
    Journal of Allergy and Clinical Immunology, 2020
  • Performance assessment of SARS-CoV-2 PCR assays developed by who referral laboratories
    Sibyle Etievant, Antonin Bal, Vanessa Escuret, Karen Brengel-Pesce, Maude Bouscambert, Valérie Cheynet, Laurence Generenaz, Guy Oriol, Gregory Destras, Geneviève Billaud, Laurence Josset, Emilie Frobert, Florence Morfin, Alexandre Gaymard
    Journal of Clinical Medicine, 2020
  • Clinical and virological data of the first cases of COVID-19 in Europe: a case series
    Francois-Xavier Lescure, Lila Bouadma, Duc Nguyen, Marion Parisey, Paul-Henri Wicky, Sylvie Behillil, Alexandre Gaymard, Maude Bouscambert-Duchamp, Flora Donati, Quentin Le Hingrat, Vincent Enouf, Nadhira Houhou-Fidouh, Martine Valette, Alexandra Mailles, Jean-Christophe Lucet, France Mentre, Xavier Duval, Diane Descamps, Denis Malvy, Jean-François Timsit, Bruno Lina, Sylvie van-der-Werf, Yazdan Yazdanpanah
    Lancet Infectious Diseases, 2020
  • First cases of coronavirus disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020
    Gianfranco Spiteri, James Fielding, Michaela Diercke, Christine Campese, Vincent Enouf, Alexandre Gaymard, Antonino Bella, Paola Sognamiglio, Maria José Sierra Moros, Antonio Nicolau Riutort, Yulia V. Demina, Romain Mahieu, Markku Broas, Malin Bengnér, Silke Buda, Julia Schilling, Laurent Filleul, Agnès Lepoutre, Christine Saura, Alexandra Mailles, Daniel Levy-Bruhl, Bruno Coignard, Sibylle Bernard-Stoecklin, Sylvie Behillil, Sylvie van der Werf, Martine Valette, Bruno Lina, Flavia Riccardo, Emanuele Nicastri, Inmaculada Casas, Amparo Larrauri, Magdalena Salom Castell, Francisco Pozo, Rinat A. Maksyutov, Charlotte Martin, Marc Van Ranst, Nathalie Bossuyt, Lotta Siira, Jussi Sane, Karin Tegmark-Wisell, Maria Palmérus, Eeva K. Broberg, Julien Beauté, Pernille Jorgensen, Nick Bundle, Dmitriy Pereyaslov, Cornelia Adlhoch, Jukka Pukkila, Richard Pebody, Sonja Olsen, Bruno Christian Ciancio
    Eurosurveillance, 2020
  • Web-based analysis of adherence to influenza vaccination among French healthcare workers
    Maxime Pichon, Alexandre Gaymard, Hugo Zamolo, Charlotte Bazire, Martine Valette, François Sarkozy, Bruno Lina
    Journal of Clinical Virology, 2019
  • Which sample for the transport of mycoplasma, eswab® or dry swab?
    Maxime Pichon, Rémi Gebeile, Bruno Lina, Géraldine Jacquet, Alexandre Gaymard
    Annales De Biologie Clinique, 2019
  • Clinical management and viral genomic diversity analysis of a child's influenza A(H1N1)pdm09 infection in the context of a severe combined immunodeficiency
    Maxime Pichon, Caroline Picard, Bruno Simon, Alexandre Gaymard, Cécile Renard, Bruno Massenavette, Christophe Malcus, Guillaume Monneret, Florence Morfin-Sherpa, Martine Valette, Etienne Javouhey, Gilles Millat, Bruno Lina, Laurence Josset, Vanessa Escuret
    Antiviral Research, 2018
  • How to manage chickenpox during pregnancy: Case reports
    Alexandre Gaymard, Maxime Pichon, Antonin Bal, Mona Massoud, Annie Buenerd, Jérôme Massardier, Danièle Combourieu, Laurent Guibaud, Pascal Gaucherand, Bruno Lina, Yahia Mekki, Florence Morfin, Pierre-Adrien Bolze
    Annales De Biologie Clinique, 2018
  • Genetic characterization of respiratory syncytial virus highlights a new BA genotype and emergence of the ON1 genotype in Lyon, France, between 2010 and 2014
    Alexandre Gaymard, Maude Bouscambert-Duchamp, Maxime Pichon, Emilie Frobert, Julien Vallee, Bruno Lina, Jean-Sébastien Casalegno, Florence Morfin
    Journal of Clinical Virology, 2018
  • Human infections with avian influenza A(H7N9) virus: Emergence of viruses, evolution, and pandemic risk
    A. Gaymard, É. Frobert, B. Lina, V. Escuret
    Virologie, 2017
  • Characterization of oseltamivir-resistant influenza virus populations in immunosuppressed patients using digital-droplet PCR: Comparison with qPCR and next generation sequencing analysis
    Maxime Pichon, Alexandre Gaymard, Laurence Josset, Martine Valette, Gilles Millat, Bruno Lina, Vanessa Escuret
    Antiviral Research, 2017
  • Vaginal neoplasia induced by an unusual papillomavirus subtype in a woman with inherited chromosomally integrated human herpesvirus type 6A
    Maxime Pichon, Alexandre Gaymard, Karine Lebail-Carval, Emilie Frobert, Etienne Beaufils, Gautier Chene, Massimo Tommasino, Bruno Lina, Pascal Gaucherand, Agnès Gautheret-Dejean, Pascale Bonnafous, Tarik Gheit, Annie Buenerd, Gery Lamblin, Yahia Mekki
    Gynecologic and Obstetric Investigation, 2017
  • Functional balance between neuraminidase and haemagglutinin in influenza viruses
    A. Gaymard, N. Le Briand, E. Frobert, B. Lina, V. Escuret
    Clinical Microbiology and Infection, 2016
  • Impact on antiviral resistance of E119V, I222L and R292K substitutions in influenza A viruses bearing a group 2 neuraminidase (N2, N3, N6, N7 and N9)
    Alexandre Gaymard, Aymeric Charles-Dufant, Murielle Sabatier, Jean-Claude Cortay, Emilie Frobert, Caroline Picard, Jean-Sébastien Casalegno, Manuel Rosa-Calatrava, Olivier Ferraris, Martine Valette, Michèle Ottmann, Bruno Lina, Vanessa Escuret
    Journal of Antimicrobial Chemotherapy, 2016
  • Methicillin-resistant Staphylococcus aureus in the environment of public transport: data from the metropolitan network in Lyon, France
    Alexandre Gaymard, Maxime Pichon, Michaël Degaud, Jason Tasse, Céline Dupieux, Frédéric Laurent
    International Journal of Antimicrobial Agents, 2016
  • Diagnostic difficulties of factor XI deficiencies: Interferences' assay or real deficit?
    Alexandre Gaymard, Christophe Nougier
    Annales De Biologie Clinique, 2016
  • HA-NA balance of A(H1N1) influenza viruses
    N. Le Briand, J. Casalegno, V. Escuret, A. Gaymard, B. Lina, M. Ottmann, É. Frobert
    Virologie, 2016

RECENT SCHOLAR PUBLICATIONS

  • High Nasopharyngeal SARS-CoV-2 Load and Delayed Clearance in Hospitalized Patients With Blood Autoantibodies Neutralizing Type I Interferons
    A Marchal, T Kerdiles, A Perrin, A Gervais, P Bastard, L Bizien, G Lingas, ...
    The Journal of Infectious Diseases, jiag172 , 2026
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  • Efficacy, safety, pharmacokinetics, immunogenicity, and serum neutralizing activity of AZD7442 (tixagevimab-cilgavimab) in patients hospitalized with COVID-19: long-term …
    CR Massonnaud, N Peiffer-Smadja, P Poignard, S Jamard, F Goehringer, ...
    Clinical Microbiology and Infection 32 (4), 618-628 , 2026
    2026
    Citations: 1
  • Efficacy, safety, pharmacokinetics, immunogenicity, and serum neutralizing activity of AZD7442 (tixagevimab-cilgavimab) in patients hospitalized with COVID-19: long-term …
    CR Massonnaud, N Peiffer-Smadja, P Poignard, S Jamard, F Goehringer, ...
    Clinical Microbiology and Infection , 2025
    2025
  • Community and Hospital‐Based Laboratory Surveillance for Influenza, Respiratory Syncytial Virus, and SARS‐CoV‐2 During the 2023–2024 Season, Lyon, France
    C Chauvel, JS Casalegno, B Visseaux, V Vieillefond, S Haim‐Boukozba, ...
    Journal of Medical Virology 97 (9), e70549 , 2025
    2025
    Citations: 2
  • Clinical research in rapid sequence during a pandemic: Lessons learned and the way forward
    F Ader, É Aubret, N Bergaud, M Bouscambert-Duchamp, S Circosta, ...
    Infectious Diseases Now, 105135 , 2025
    2025
  • Performance of Subgenomic RT‐PCR for Predicting SARS‐CoV‐2 Infectivity Compared to Genomic RT‐PCR and Culture Isolation
    C Sentis, D Parraud, G Billaud, M Valette, M Bouscambert‐Duchamp, ...
    Journal of Medical Virology 97 (5), e70363 , 2025
    2025
  • sST2 is a key outcome biomarker in COVID-19: insights from discovery randomized trial
    DM Smadja, CR Massonnaud, A Philippe, M Rosa, S Luneau, A Rauch, ...
    Scientific Reports 15 (1), 14348 , 2025
    2025
    Citations: 4
  • Performance of whole genome sequencing for respiratory syncytial virus: insights from the first external quality assessment, France, 2024
    A Moisan, H Regue, Y Rahou, A Gaymard, A Oblette, L Avon, N Bergaud, ...
    Clinical Microbiology and Infection 31 (4), 647-650 , 2025
    2025
  • Community and hospital-based laboratory surveillance for influenza, RSV, and SARS-CoV-2 during the 2023-2024 season, Lyon, France
    C Chauvel, JS Casalegno, B VISSEAUX, V Vieillefond, S Haim-Boukozba, ...
    Authorea Preprints , 2025
    2025
  • Genotypic and phenotypic characterisation of respiratory syncytial virus after nirsevimab breakthrough infections: a large, multicentre, observational, real-world study
    S Fourati, A Reslan, J Bourret, JS Casalegno, Y Rahou, L Chollet, S Pillet, ...
    The Lancet Infectious Diseases 25 (3), 301-311 , 2025
    2025
    Citations: 71
  • Advancing respiratory virus diagnostics: integrating the nasal IFN-I score for improved viral detection
    M Mommert-Tripon, D Parraud, C Grosbois, A Gaymard, V Cheynet, ...
    EBioMedicine 110 , 2024
    2024
    Citations: 3
  • Antiviral effect of Evusheld in COVID-19 hospitalized patients infected with pre-Omicron or Omicron variants: a modelling analysis of the randomized DisCoVeRy trial
    M Beaulieu, A Gaymard, C Massonnaud, N Peiffer-Smadja, ...
    Journal of Antimicrobial Chemotherapy 79 (11), 2887-2895 , 2024
    2024
    Citations: 6
  • Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection
    A Marchal, ET Cirulli, I Neveux, E Bellos, RS Thwaites, KMS Barrett, ...
    Human Genetics and Genomics Advances 5 (3) , 2024
    2024
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  • Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms
    BW Citarella, C Kartsonaki, ED Ibáñez-Prada, BP Gonçalves, J Baruch, ...
    Heliyon 10 (10) , 2024
    2024
    Citations: 2
  • Impact of the H274Y Substitution on N1, N4, N5, and N8 Neuraminidase Enzymatic Properties and Expression in Reverse Genetic Influenza A Viruses
    A Gaymard, C Picard, G Vazzoler, P Massin, E Frobert, M Sabatier, ...
    Viruses 16 (3), 388 , 2024
    2024
    Citations: 2
  • Immunomodulators for immunocompromised patients hospitalized for COVID-19: a meta-analysis of randomized controlled trials
    II Siempos, AC Kalil, D Belhadi, VC Veiga, AB Cavalcanti, ...
    EClinicalMedicine 69 , 2024
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    Citations: 8
  • Tixagevimab-cilgavimab (AZD7442) for the treatment of patients hospitalized with COVID-19 (DisCoVeRy): a phase 3, randomized, double-blind, placebo-controlled trial
    M Hites, CR Massonnaud, EL Lapique, D Belhadi, S Jamard, ...
    Journal of Infection 88 (3) , 2024
    2024
    Citations: 9
  • Gestion des prélèvements biologiques d’un patient suspect ou confirmé d’infection par le virus monkeypox (MPV)
    M Bouscambert, S Burrel, O Ferraris, N Lemaitre, S Allix, A Merens, B Lina, ...
    Revue de biologie médicale 381 (6), 73-77 , 2024
    2024
  • Implementation of Recommendations on the Use of Corticosteroids in Severe COVID-19
    F Camirand-Lemyre, L Merson, BKT Vijayaraghavan, AJC Burrell, ...
    JAMA network open 6 (12), e2346502-e2346502 , 2023
    2023
    Citations: 10
  • Association between SARS‐CoV‐2 viral kinetics and clinical score evolution in hospitalized patients
    N Néant, G Lingas, A Gaymard, D Belhadi, M Hites, T Staub, R Greil, ...
    CPT: Pharmacometrics & Systems Pharmacology , 2023
    2023
    Citations: 5

MOST CITED SCHOLAR PUBLICATIONS

  • Clinical and virological data of the first cases of COVID-19 in Europe: a case series
    FX Lescure, L Bouadma, D Nguyen, M Parisey, PH Wicky, S Behillil, ...
    The Lancet Infectious Diseases 20 (6), 697-706 , 2020
    2020
    Citations: 1461
  • First cases of coronavirus disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020
    G Spiteri, J Fielding, M Diercke, C Campese, V Enouf, A Gaymard, A Bella, ...
    Eurosurveillance 25 (9), 2000178 , 2020
    2020
    Citations: 861
  • Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
    P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ...
    Science immunology 6 (62), eabl4340 , 2021
    2021
    Citations: 674
  • X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19
    T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ...
    Science immunology 6 (62), eabl4348 , 2021
    2021
    Citations: 460
  • Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled …
    F Ader, M Bouscambert-Duchamp, M Hites, N Peiffer-Smadja, J Poissy, ...
    The Lancet Infectious Diseases 22 (2), 209-221 , 2022
    2022
    Citations: 447
  • Cluster of coronavirus disease 2019 (COVID-19) in the French Alps, February 2020
    K Danis, O Epaulard, T Bénet, A Gaymard, S Campoy, E Botelho-Nevers, ...
    Clinical Infectious Diseases 71 (15), 825-832 , 2020
    2020
    Citations: 365
  • Type I IFN immunoprofiling in COVID-19 patients
    S Trouillet-Assant, S Viel, A Gaymard, S Pons, JC Richard, M Perret, ...
    Journal of Allergy and Clinical Immunology 146 (1), 206-208. e2 , 2020
    2020
    Citations: 330
  • Characterization and treatment of SARS-CoV-2 in nasal and bronchial human airway epithelia
    A Pizzorno, B Padey, T Julien, S Trouillet-Assant, A Traversier, ...
    Cell Reports Medicine 1 (4) , 2020
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    Citations: 276
  • Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69–V70, France, August to December 2020
    A Bal, G Destras, A Gaymard, K Stefic, J Marlet, S Eymieux, H Regue, ...
    Eurosurveillance 26 (3), 2100008 , 2021
    2021
    Citations: 274
  • Low levels of respiratory syncytial virus activity in Europe during the 2020/21 season: what can we expect in the coming summer and autumn/winter?
    J van Summeren, A Meijer, G Aspelund, JS Casalegno, G Erna, U Hoang, ...
    Eurosurveillance 26 (29), 2100639 , 2021
    2021
    Citations: 254
  • Modeling SARS-CoV-2 viral kinetics and association with mortality in hospitalized patients from the French COVID cohort
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    Proceedings of the National Academy of Sciences 118 (8), e2017962118 , 2021
    2021
    Citations: 253
  • The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
    J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ...
    Proceedings of the National Academy of Sciences 119 (21) , 2022
    2022
    Citations: 217
  • Functional balance between Neuraminidase and Hemagglutinin in influenza viruses
    A Gaymard, N Le Briand, E Frobert, B Lina, V Escuret
    Clinical Microbiology and Infection , 2016
    2016
    Citations: 214
  • Characteristics of the delayed respiratory syncytial virus epidemic, 2020/2021, Rhône Loire, France
    JS Casalegno, D Ploin, A Cantais, E Masson, E Bard, M Valette, R Fanget, ...
    Eurosurveillance 26 (29), 2100630 , 2021
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    Citations: 121
  • Performance Assessment of SARS-CoV-2 PCR Assays Developed by WHO Referral Laboratories
    S Etievant, A Bal, V Escuret, K Brengel-Pesce, M Bouscambert, V Cheynet, ...
    Journal of Clinical Medicine 9 (6), 1871 , 2020
    2020
    Citations: 111
  • COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
    Infection 49 (5), 889-905 , 2021
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