Rudyard dos Santos Oliveira
@ufpb.br
PPGO - UFPB - BRAZIL
RESEARCH, TEACHING, or OTHER INTERESTS
Dentistry
Scopus Publications
- Diagnostic Accuracy of Dentin Sclerosis by Optical Coherence Tomography and the North Carolina Index in Noncarious Cervical Lesions
Nathalie Murielly Rolim de Abreu, Rudyard dos Santos Oliveira, Anauara Lima e Silva, Laryssa Mylenna Madruga Barbosa, Alessandro Dourado Loguercio, et al.
Journal of Esthetic and Restorative Dentistry, 2026
Objective To evaluate the diagnostic accuracy of optical coherence tomography (OCT) and the North Carolina Index (NCI) for identifying dentin type (sclerotic vs. nonsclerotic) in natural noncarious cervical lesions (NCCLs). Materials and Methods Thirty extracted human premolars with 30 NCCLs (90 regions of interest) were analyzed. Two blinded, calibrated examiners classified dentin using OCT and NCI. NCI was tested with two sclerosis thresholds. A dichotomous OCT classification considered dentin aspects before and after contrast solution application. An alternative four‐level OCT index, based on the dichotomous classification in three lesion regions, was also tested. Scanning electron microscopy (SEM) was the reference standard. Diagnostic metrics were calculated with 95% confidence intervals. Results The dichotomous OCT showed high accuracy in detecting sclerosis (0.86; 95% CI: 0.77–0.92), with sensitivity of 0.81 and specificity of 0.94, while the four‐level OCT index showed lower performance (accuracy of 0.70; 95% CI: 0.51–0.85; sensitivity of 0.75, and specificity of 0.67). NCI exhibited poor accuracy (0.47; 95% CI: 0.27–0.67), low sensitivity (0.41 and 0.67), and specificity (0.50 and 0.33), and nonsignificant correlation with SEM ( p = 0.65). Conclusion OCT was sensitive and specific for diagnosing dentin type in NCCLs, outperforming NCI, which showed unsatisfactory performance. OCT demonstrates strong potential for reliably assessing dentin sclerosis. Clinical Significance Although NCI is widely used for clinical evaluation, OCT has proven to be a more accurate technique for classifying dentin type in NCCLs, providing possible predictability of the dentin substrate and assisting in the choice of restorative technique and material. - Facial Growth Patterns and Midpalatal Suture Maturation in Adults: A Retrospective CBCT-Based Observational Study
Elizabety do Nascimento Silva, Nathalie Murielly Rolim de Abreu, Frederico Barbosa de Sousa, Francine Kuhl Panzarella, Rudyard dos Santos Oliveira
Orthodontics and Craniofacial Research, 2026
Objective To investigate whether facial growth pattern is associated with the maturation stage of the midpalatal suture (MPS) in adults using cone‐beam computed tomography (CBCT). Materials and Methods This retrospective study reviewed 300 full‐skull CBCT scans acquired between January 2018 and May 2023, of which 120 met the eligibility criteria. Individuals aged 18 years or older were classified according to facial growth pattern (brachyfacial, mesofacial or dolichofacial) using Ricketts' VERT index. Age was categorised into < 30 and ≥ 30 years based on clinical evidence suggesting increased frequency of sutural fusion after the third decade of life. Exclusion criteria included craniofacial anomalies, syndromic conditions, systemic or hormonal disorders affecting skeletal growth, impacted teeth, previous maxillary surgery, trauma and inadequate image quality. MPS maturation was assessed using Angelieri's five‐stage classification (A–E). Two calibrated examiners independently evaluated all cephalometric and tomographic records. Ordinal multinomial logistic regression was applied to analyse associations between facial growth pattern, age, sex and MPS maturation stage. Results Facial growth pattern was significantly associated with MPS maturation stage (χ 2 = 20.65, p < 0.001), with dolichofacial individuals more frequently presenting earlier maturation stages (B or C). Age ( p = 0.297) and sex ( p = 0.870) were not significantly associated with MPS maturation in this adult sample. Reliability analysis demonstrated excellent intra‐ and inter‐examiner agreement (ICC = 0.95; κ = 0.98). Conclusion Facial growth pattern was associated with MPS maturation stage in adults and may function as an adjunctive diagnostic parameter. Dolichofacial individuals more frequently exhibited earlier stages of sutural maturation, whereas age and sex showed no significant association. Although facial pattern analysis should not replace CBCT evaluation, it may contribute to a more individualised, anatomy‐based diagnostic assessment. These findings should be interpreted cautiously due to the cross‐sectional design and specific population studied. - Effect of nanoparticle incorporation on antimicrobial activity and shear bond strength of orthodontic adhesives: a scoping review
Nathalie Murielly Rolim de Abreu, Frederico Barbosa de Sousa, Rudyard dos Santos Oliveira
Saudi Dental Journal, 2025
Nanoparticle incorporation into orthodontic adhesives has emerged as a strategy to enhance antimicrobial properties, improve mechanical performance, and prevent enamel demineralization during fixed appliance therapy. This scoping review aimed to synthesize evidence on the effectiveness of nanoparticle-modified orthodontic adhesives. A systematic search and independent screening process were conducted by two reviewers across multiple databases following the PRISMA-ScR guidelines. Among the 153 initially identified records, 25 studies met the inclusion criteria. Most studies (72%) were in vitro, whereas only 12% used in situ models. Preclinical studies are scarce (4%), emphasizing the gap between laboratory findings and clinical application. Silver nanoparticles (AgNPs), which demonstrate strong antimicrobial activity against S. mutans, E. coli, and S. aureus while maintaining acceptable bond strength at moderate concentrations, have been the most frequently investigated. Other nanoparticles, such as titanium dioxide (TiO₂), β-AgVO₃, mesoporous bioactive glass nanoparticles (MBNs), calcium phosphate compounds, and calcium phosphate compounds, also show promising antimicrobial and remineralization properties. However, variations in study designs, nanoparticle concentrations, and adhesive formulations hinder direct comparisons. Despite promising laboratory findings, the clinical application of nanoparticle-modified orthodontic adhesives remains uncertain due to the lack of standardized methodologies and long-term clinical validation. Further well-designed clinical trials are essential to confirm their efficacy, safety, and impact on orthodontic bonding performance under real-world conditions. Standardization of nanoparticle formulations and biocompatibility assessments are crucial to ensure their practical integration into orthodontic practice, promoting safer and more effective treatments. - Spatially resolved composition of bovine dental enamel in permanent incisors
Nathalie Murielly Rolim de Abreu, Rudyard dos Santos Oliveira, Frederico Barbosa de Sousa
Archives of Oral Biology, 2025 - Postoperative Complications After Extraction of Impacted Mandibular Third Molars: A Clinical Observational Study On Dental Position And Risks
Daniela Camila Nunes Miguel, Rudyard dos Santos Oliveira, Francine Kühl Panzarella
Journal of International Society of Preventive and Community Dentistry, 2025
Aim: This study examined the associations between the position of impacted mandibular third molars and postoperative complications, with a focus on pain, swelling, and their associations with proximity to the mandibular canal. Methods: A retrospective cohort of 270 patients who underwent surgical extraction of mandibular third molars was analyzed. Preoperative panoramic radiographs were evaluated by three experienced surgeons to classify the tooth position (Winter classification) and proximity to the mandibular canal (Rood and Shehab classification). Postoperative complications (pain, swelling, trismus, paresthesia, hematoma, and hemorrhage) were assessed via standardized questionnaires and clinical records 7 days postoperatively. Data analysis included descriptive statistics and multinomial logistic regression. Results: Mesioangular and horizontal impactions were significantly associated with increased postoperative pain and swelling. Logistic regression indicated that the mesioangular position increased the odds of pain by 95% (odds ratio [OR] = 1.95) and swelling by 85% (OR = 1.85). The horizontal impact increased the odds of pain by 2.8 times (OR = 2.8) and swelling by 5.0 times (OR = 5.0). Tooth position was a significant predictor of postoperative complications (P = 0.007), whereas proximity to the mandibular canal, patient age, and the mandibular side were not. Root darkening emerged as a notable radiographic finding. Conclusions: The position of impacted mandibular third molars, particularly mesioangular and horizontal angulations, significantly influences postoperative pain and swelling. These findings highlight the importance of considering the tooth position in surgical planning to reduce complications. Although panoramic radiography is useful in resource-limited settings, cone-beam computed tomography is advised for complex cases or when vital structures are at risk. - Evaluation of dental enamel after debonding of sapphire brackets and removal of orthodontic adhesive remnants
Elizabety do Nascimento SILVA, Daniel Magalhães QUINTANS, Rebeca Tibau Aguiar DIAS, Frederico Barbosa de SOUZA, Rudyard dos Santos OLIVEIRA
Dental Press Journal of Orthodontics, 2025
Introduction: Iatrogenic effects on dental enamel are common during the debonding of aesthetic brackets and the removal of residual adhesive. Objective: To evaluate the impact of these procedures on enamel integrity via advanced imaging techniques. Methods: Human premolar crowns (n=60) were bonded with sapphire brackets and debonded using 346R pliers (G1, n=30) and 346B pliers (G2, n=30). Adhesive removal was performed with a multilaminated zirconia bur (EG1, n=30) and a multilaminated carbide bur (EG2, n=30). Surface roughness was assessed via optical profilometry; enamel loss and microcracks, via microcomputed tomography; and the adhesive remnant index (ARI), via optical coherence tomography. After normality and homogeneity tests, Mann-Whitney and Wilcoxon tests were applied (p<0.05). Results: The 346R plier presented a slightly higher ARI than the 346B plier. Both removal methods significantly increased surface roughness, without causing enamel microcracks. The zirconia bur demonstrated greater adhesive removal efficiency but was associated with increased enamel loss. Conclusions: Variations in the shape and force vector of the pliers did not affect enamel outcomes. The zirconia bur system at low speed was more efficient at removing orthodontic adhesive remnants, resulting in a lower final ARI on the enamel surface, and none of the procedures caused enamel microcracks, as evaluated by microcomputed tomography. - Maturation stages of the sutures in the median palatine evaluated with cone-beam computed tomography
Rudyard dos Santos Oliveira, Carlos José Maia de Oliveira, Francine Kühl Panzarella, José Luiz Cintra Junqueira
American Journal of Orthodontics and Dentofacial Orthopedics, 2021 - Prevalence of temporomandibular joint disorders in patients with ankylosing spondylitis: A cross-sectional study
Rebeca Cecília Souza, Emerson Tavares de Sousa, David Sousa, Marcelo Sales, Rudyard dos Santos Oliveira, et al.
Clinical Cosmetic and Investigational Dentistry, 2021
Background This study sought to investigate which temporomandibular disorders (TMD) can be expected in patients with ankylosing spondylitis (AS) and to determine the combined impact of these conditions on the psychological status, chronic pain, and functional disability. Material and Methods A cross-sectional study composed of 30 patients between 18 and 65 years with ankylosing spondylitis was performed. The research protocol considered the evaluation of outcomes related to the ankylosing spondylitis (HLA-B27 antigen, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI) and Health Assessment Questionnaire – Spondylitis (HAQ-S)) and temporomandibular disorders (axis I and II of the Research Diagnostic Criteria for Temporomandibular Disorders – RDC/TMD). Descriptive analyses were applied to express the results. Results The sample presented both AS and TMD, most of them (24) were diagnosed with conventional AS (HLA-B27 positive). The BASDAI was scored as 7.70 (2.30) (high activity of AS disease). Functional disability represented by high scores of BASFI [7.00 (2.63)] and HAQ-S [1.79 (0.62)] demonstrates the severe impact of the disease on the daily routine and quality of life. According to RDC/TMD diagnostic criteria, 17 (57%) share the three groups of TMD, and 9 (30%) share two groups of TMD (Group I and III). Over 73% of the volunteers scored high levels of chronic pain (Grade III and IV) associated with a high depression scale score. The sample scored the somatization scale (with and without pain) as severe. Conclusion Patients with ankylosing spondylitis presented a high prevalence of temporomandibular disorder, most of them having the degenerative forms of TMJ disease. AS and TMD cause moderate to severe chronic pain and a negative impact on psychological status and functional capacities. - Accuracy of panoramic radiography for degenerative changes of the temporomandibular joint
Rudyarddos Santos Oliveira, SilvioR Oliveira, ErnestoD Rodrigues, José LuizC Junqueira, FrancineK Panzarella
Journal of International Society of Preventive and Community Dentistry, 2020
Background: Temporomandibular joint (TMJ) morphologies are complex, and changes in joint components have been studied extensively. TMJ conditions have many different etiologies, appearances, and relevant clinical significance. Objective: The objective of this study was to evaluate the concordance of the diagnosis of degenerative changes in the TMJ in panoramic radiographs. Materials and Methods: Cone beam computed tomography (CBCT) was used as a reference standard. Images of 84 patients (168 TMJs), 61 females (72.6%) and 23 males (27.4%) with an average age of 47.4 years, were evaluated by three radiologists who established the presence or absence of degenerative changes in the jaw heads. The data were collected and organized in a spreadsheet. Concordance between evaluators was analyzed using agreement percentages, statistical κ, and confidence intervals. In the analysis of compliance with CBCT, sensitivity, specificity, predictive positive and negative values, and probabilities of false positives and negatives were also calculated. All inferential tests were performed with a 5% significance level. Results: The percentage of agreement among raters in panoramic radiographs ranged from 66.7% to 82.9%, considered mild to moderate. Correlation between radiographic and tomographic images ranged from 45.5% to 64.9% in the inter-evaluator reviews, representing a very mild agreement. Sensitivity ranged from 28.6% to 58.7% and specificity from 66.7% to 100.0%. Positive predictive value ranged from 77.1% to 100.0%; the negative predictive value was lower, ranging from 32.2% to 54.8%. The probability of false negatives was higher than that of false positives, ranging from 45.2% to 67.8%. Conclusion: The rater did not reach acceptable diagnosis levels. - Evaluation of bone repair in the mandible of rabbits using biphasic calcium phosphate micro-macroporous hydroxyapatite bioceramics and beta-tricalcium phosphate
Francisco Franceschini Neto, Rudyard dos Santos Oliveira, Ana Paula Altheman Lopes, Carlos Eduardo Xavier dos Santos Ribeiro da Silva
Pesquisa Brasileira Em Odontopediatria E Clinica Integrada, 2019
Objective: To perform a clinical and histological evaluation, characterizing and proving the feasibility of the use of beta tricalcium phosphate (HA/βTCP) bioceramics as a bone defect repair material, comparing it with autogenous bone and blood clot in terms of osteoinductive, conductive, and genic capacities. Material and Methods: The experiment was based on 3 critical defects in the mandible of 11 New Zealand rabbits. The defects were filled with HA/βTCP bioceramics and autogenous bone, respectively, collected and ground during the development of defects and blood clots. The animals were euthanized after the 90-day experiment and samples were collected for histomorphological examination. To evaluate differences between the groups, a one-way analysis of variance (ANOVA) was performed with Tukey’s post hoc test. An αvalue lower than 0.05 was considered statistically significant. Results: Microscopy revealed the presence of osteoblasts, osteoclasts, and osteocytes associated or not associated with the presence of mature or immature bone. All the studied materials presented bone neoformation in all cases, with the presence of mature and immature bone. Regarding the presence of HA/βTCP bioceramic residual material, the same was found in 7 of 11 slides. Conclusion: HA/βTCP bioceramics were shown to be a biocompatible bone substitute, with osteoinductive and osteoconductive characteristics, accelerating the process of new bone formation when compared with autogenous and blood clotted bone, thereby showing promise for bone defect repair with safety and efficacy. - Evaluation of incidental findings on cone beam computed tomography
Rudyard dos Santos Oliveira, Jane Tereza Peretto, Francine Küll Panzarella, Ricardo Raitz
Pesquisa Brasileira Em Odontopediatria E Clinica Integrada, 2019 - Self-perception of Brazilian adolescents who need orthodontic treatment
RS Oliveira, FM Flório, AMG Oliveira
Pesquisa Brasileira Em Odontopediatria E Clinica Integrada, 2018 - Morphometric Analysis of the Mental Foramen Using Cone-Beam Computed Tomography
Rudyard dos Santos Oliveira, Maria Rodrigues Coutinho, Francine Kühl Panzarella
International Journal of Dentistry, 2018 - Association between the anatomy of the mandibular canal and facial types: A cone-beam computed tomography analysis
Rudyard dos Santos Oliveira, Arlete Maria Gomes Oliveira, José Luiz Cintra Junqueira, Francine Kühl Panzarella
International Journal of Dentistry, 2018 - Otomandibular microsomia: Case report
Dmitry José de Santana Sarmento, Jalber Almeida dos Santos, Lúcia Helena Marques de Almeida Lima, Marcelino Guedes de Lima, Gustavo Pina Godoy
Brazilian Journal of Otorhinolaryngology, 2011