Vignesh Kailasam
@sriramachandra.edu.in
Professor and Head
Sri Ramachandra Institute of Higher Education and Research
Orthodontist
RESEARCH, TEACHING, or OTHER INTERESTS
Orthodontics, Health Professions
FUTURE PROJECTS
Growth
Applications Invited
Toxicity
Applications Invited
Scopus Publications
Scopus Publications
Yuvashree Raghupathy, Venkateswaran Ananthanarayanan, and Vignesh Kailasam
Elsevier BV
M. S. Muthu, V. Kailasam, U. Rao, C. Krithika, M. Kirthiga, A. Jagadeesan, and A. Warrier
Springer Science and Business Media LLC
Vignesh Kailasam, Mrithulaa Vadivel Kumar, and Annapurna Kannan
Jaypee Brothers Medical Publishing
M. Dilip Kumar, Haritha Pottipalli Sathyanarayana, and Vignesh Kailasam
Galenos Yayinevi
Objective: We aimed to evaluate the effectiveness of functional mandibular advancer (FMA) in treating growing patients with Class II malocclusion. Methods: Electronic searches were conducted in MEDLINE (via PubMed), Cochrane Library, Web of Science, Scopus, Embase, and Lilacs from 1945 to 30th November 2021. Studies were selected based on the following inclusion criteria: human studies, Class II growing patient treated with FMA, untreated control group or a comparable group treated with another fixed functional appliance, pre- and post-treatment lateral cephalograms/magnetic resonance imaging/cone-beam computed tomography, randomized clinical trials, prospective studies, and retrospective studies. Data extraction of the included articles was independently performed independently by two authors. The risk of bias was assessed using the ROBINS-I tool. Meta-analysis was performed using the inverse generic model. Results: Seven articles met the criteria and were included in the systematic review and three articles were included in the meta-analysis. Three studies had at low risk of bias and four studies had a moderate risk of bias. All articles reported anterior positioning of the mandible along with an increase in mandibular length. The meta-analysis results indicated a negligible difference between FMA and other functional appliances for the parameters SNA [0.11, 95% confidence interval (CI) of -1.07 and 1.29] and ANB (-1.00, 95% CI of -1.34 and -0.65). The evidence was limited for soft tissue changes. Conclusion: Class II correction with FMA involved a combination of skeletal and dentoalveolar changes and was similar to other fixed functional appliances.
Yuvashree Raghupathy, Venkateswaran Ananthanarayanan, Vignesh Kailasam, and Sridevi Padmanabhan
Jaypee Brothers Medical Publishing
Abstract Background Skeletal class III malocclusion is a challenging condition that orthodontists frequently come across. The facemask (FM) is a device commonly used to treat this malocclusion. However, the stability of this orthopedic correction remains unclear, and collective documentation of the short-, mid-, and long-term stability after FM therapy is necessary. Aim The aim of the systematic review was to assess posttreatment stability following FM therapy in patients with skeletal class III malocclusion. Materials and methods Through a predefined search strategy, electronic searching was conducted in PubMed, Latin American and Caribbean Health Sciences Literature (LILACS), Cochrane, Ovid, Embase, Scopus, and Web of Science until 30th June 2022. Eligible study selection, data extraction, and evaluation of the risk of bias were performed independently by two review authors according to the Cochrane tool for assessing the risk of bias in randomized trials (RoB 2.0 tool) and the Risk of Bias in Nonrandomized Studies–of Interventions (ROBINS-I) tool for nonrandomized trials. A total of 14 studies were finally considered eligible. The systematic review revealed that the maxillo-mandibular differential reverted to class III. The maxillary changes achieved were variable, with SNA angles ranging between −0.7° and 1.9°. Changes in the mandible were greater with an increase in the SNB angle ranging between 0.33° and 3.62°. The lower anterior facial height increased. The maxillary and mandibular incisors were proclined, and the overjet and overbite decreased. The soft tissue changes were insignificant. Conclusion The effects of FM therapy were found to be stable in the short-term follow-up period. The long-term follow-up revealed that the effects of FM therapy remained stable for the maxilla. However, the mandible continued to grow in a horizontal and unfavorable direction until the adolescent growth spurt. Clinical significance The major variable that determines the long-term success of FM therapy is the amount and direction of mandibular growth during the adolescent growth spurt. More focus on restricting unfavorable mandibular growth and duration of retention is needed for post-FM therapy. Others PROSPERO (CRD42021218960). How to cite this article Raghupathy Y, Ananthanarayanan V, Kailasam V, et al. Posttreatment Stability Following Facemask Therapy in Patients with Skeletal Class III Malocclusion: A Systematic Review. Int J Clin Pediatr Dent 2023;16(6):897–907.
Prathima Anita, Haritha Pottipalli Sathyanaryana, Kennedy Kumar P, Krishnapriya Ramanathan, and Vignesh Kailasam
Elsevier BV
Prathima Anita, Haritha Pottipalli Sathyanarayana, Kennedy Kumar, Krishnapriya Ramanathan, and Vignesh Kailasam
Elsevier BV
Ramyaja Chunduru, Pamila Rachel, Vignesh Kailasam, and Sridevi Padmanabhan
Galenos Yayinevi
This systematic review was intended to evaluate the maxillary sinus dimensions in vertical and sagittal craniofacial patterns and to assess if there was a difference among the craniofacial patterns. A systematic search was performed in seven databases till February 2021. The risk of bias was performed with modified Newcastle Ottawa scale. Meta-analysis was performed using random effects model. Twelve studies were included in the review and 8 in the meta-analysis. Compared to Class I malocclusion, the maxillary sinus area is greater in Class II and lesser in Class III malocclusion. On comparing normo-divergent growth pattern, the maxillary sinus area is lesser in hypo-divergent and greater in hyper-divergent individuals. Most of the studies were graded as satisfactory. The measurements are greater in hyper-divergent Class II malocclusion and in males.
Chandnee Murugan and Vignesh Kailasam
SAGE Publications
Background: Diverse findings have been reported for the cranial base angle (CBA) in patients with CLP (cleft lip and palate) and non-CLP controls. Objective: The aim of this study is to assess and evaluate the CBA in patients with CLP and non-CLP controls. Methods: Data from PubMed, OVID Technologies, Inc., Cochrane, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Scopus, Web of Science, and EMBASE for Excerpta Medica dataBASE (EMBASE) with relevant terms was extracted until December 31, 2020. Inclusion criteria were data of patients with non-syndromic unilateral cleft lip and palate (UCLP) and bilateral cleft lip and palate (BCLP). In the case of UCLP and BCLP, patients with craniofacial syndromes were excluded. The study proposal was registered with PROSPERO (Registration number: CRD42021228632). Results: Fifteen studies with a total of 2032 participants were included for the systematic review and 14 studies with a total of 1972 participants were included for the meta-analysis. The risk of bias was assessed using the Modified Newcastle Ottawa scale under seven domains by two authors. Thirteen studies were graded as “good” and two as “satisfactory.” The CBA in patients with CLP were greater than the non CLP Class I controls in six of the 15 studies. CBA was greater in patients with CLP than non-CLP controls by 1.21° (95% CI of 0.19-2.22). Meta-analysis reported considerable heterogeneity (I2 = 86%). Anterior (ACB) and posterior cranial base (PCB) lengths were shorter in patients with CLP than in the non-cleft Class I controls by 2.14 mm (95% CI of 0.99-3.30) and 2.06 mm (95% CI of 1.52-2.60), respectively. Conclusion: Most studies were graded as good. Patients with CLP had greater CBA and shorter ACB and PCB lengths when compared to non-CLP controls.
Jaymi Anna George, Bhadrinath Srinivasan, and Vignesh Kailasam
Elsevier BV
Hita Rangarajan, Sridevi Padmanabhan, Sukanya Ranganathan, and Vignesh Kailasam
Springer Science and Business Media LLC
Vignesh Kailasam, Hita Rangarajan, Harshini Nivetha Easwaran, and Muthu MS
Elsevier BV
Vignesh Kailasam, Hita Rangarajan, Harshini Nivetha Easwaran, and M.S. Muthu
Elsevier BV
Sureka Murugaiyan, Bhadrinath Srinivasan, and Vignesh Kailasam
Wiley
AbstractObjectivesTo assess and evaluate the collum angle (CA) of the anterior teeth of the permanent dentition.MethodsA search in seven databases for articles that had measured the CA in sagittal malocclusions was conducted until November 30, 2021. The risk of bias was assessed using the Modified Newcastle Ottawa scale. CA measurements using Cone Beam Computed Tomography or lateral cephalograms were included. The CA data were summarized by random‐effects inverse generic meta‐analyses.ResultsQualitative analysis of the 17 selected articles revealed that four were rated as “very good,” 12 as “good” and 1 as “satisfactory.” CA was 4.7° (95% CI of 3.1 to 6.4) and 2.0° (95% CI of 0.1 to 3.9) greater in Class II division 2 and Class III malocclusions respectively, than in Class I malocclusion cases.ConclusionMajority of the studies were rated as good or very good. Most studies evaluated the CA of the maxillary central incisors in Class II division 2 malocclusion. Studies assessing other maxillary anterior and mandibular anterior teeth are required.Clinical SignificancePractice of esthetic dentistry for teeth with increased CA is of clinical importance since the angle would determine the longevity and esthetic/cosmetic success of the rehabilitation. Placement of dental implants in areas of missing teeth with increased collum angle leads to excessive stress between the fixture and abutment leading to gingival recession. Thus, knowledge about the collum angle of anterior teeth and its variations in sagittal malocclusions would enable precise treatment planning in the field of esthetic dentistry.
Jaymi Anna George, Annapurna Kannan, and Vignesh Kailasam
Springer Science and Business Media LLC
J Aarthi, MS Muthu, M Kirthiga, and Vignesh Kailasam
F1000 Research Ltd
Background: A new classification called OXIS was proposed for categorising the interproximal contacts of primary molars, and its prevalence was established. The aim of this study was to establish the variations in interproximal contacts of primary canines and thereby modify the OXIS classification of primary molars to primary canines. Additionally, we aimed to estimate the applicability of modifications to primary anterior teeth. Methods: A retrospective study was conducted with sectional die models obtained from a previous study of 1,090 caries-free children. Two calibrated examiners evaluated a total of 4,674 contacts from the occlusal aspect. The contacts were scored according to the former OXIS classification, with two modifications incorporated to encompass the morphological differences and rotations of primary canines and other primary anterior teeth. Results: The most prevalent contact was O (62.1%), followed by X (19.6%), I (12.6%), S type I (4.1%), and S type II (1.6%). Inter-arch comparison by means of the Chi-square test revealed significant differences for all types of contacts (P < .001). Conclusions: The interproximal contacts of canines were categorised as O, X, I, S I, and S II. The OXIS classification of primary molars was modified to befit the variations in primary canines. This study showed the presence of different types of contacts in primary canines. Identification of these contacts and their complexity has warranted a need for this to be studied as an inherent risk factor for caries risk assessment.
Indu Ravi, Bhadrinath Srinivasan, and Vignesh Kailasam
Elsevier BV
Vignesh Kailasam, Hita Rangarajan, Harshini Nivetha Easwaran, and M.S. Muthu
Elsevier BV
Prathima Anita and Vignesh Kailasam
Elsevier BV
Keerthi Venkatesan, Vignesh Kailasam, and Sridevi Padmanabhan
Elsevier BV
Bharathi Elangovan, Bhadrinath Srinivasan, Vignesh Kailasam, and Sridevi Padmanabhan
Elsevier BV
Keerthi Venkatesan, Vignesh Kailasam, and Sridevi Padmanabhan
Elsevier BV
VGokula Krishnan, Vignesh Kailasam, and ArunB Chitharanjan
Medknow
Aim: To evaluate and compare the effect of contamination with haemostatic agents like Tranexamic Acid (TA) and Ethamsylate, on the shear bond strength. Materials and Methods: There are about 100 extracted human premolars randomly segregated into four groups each consisting of 25 samples. Group I was bonded with Transbond, Group II was bonded with Transbond after blood contamination, while groups III and IV were bonded with Transbond after contamination with Tranexamic acid and the shear bond strength was measured. The data were compared by One- way ANOVA and Tukey (HSD) tests. Results: Group I had the highest shear bond strength (SBS) while Group II, where the teeth were contaminated with blood showed the least SBS values ANOVA indicated significant differences between the four groups (P < .05). Tukey HSD revealed that contamination with TA (Group III) had a statistically higher SBS that contamination with Ethamsylate (Group IV) (P < .05). Conclusion: Since tranexamic acid and ethamsylate reduces the bleeding when used during surgery, these haemostatic agents may be considered in bonding situations where blood contamination is anticipated.
Bhadrinath Srinivasan, Arun Chitharanjan, Vignesh Kailasam, Vamsi Lavu, and Vani Ganapathy
Medknow
OBJECTIVES: Leptin, a polypeptide which is related to body fat regulation, is also found to have a role in the inflammatory reaction. The aim of this study is to assess the concentration of leptin in Gingival Crevicular Fluid (GCF) during orthodontic force application and to correlate its concentration to rate of tooth movement. METHODS: Twenty orthodontic patients (10 males and 10 females) were selected for the study. Leptin concentration was measured at T0, before force application; T1, one hour after force application; T2, one day after force application; T3, one week after force application; T4, one month after force application. GCF was collected using filter paper strips from the distal aspect of gingival sulcus of the right maxillary canine distalized by an active lace-backs of tooth movement was measured on dental casts, before and one month after force application. One-way ANOVA with Bonferroni correction and Pearson's correlation test were used to analyze the data. RESULTS: The mean GCF leptin concentration increased from T0 to T1, rose to a peak at T2, then declined to a minimum value at T3 and then increased to a value at T4, closer to the base line value (T0), and it was statistically significant (P < 0.05). There was positive correlation of the overall mean leptin concentration to rate of tooth movement (correlation coefficient = 0.634). CONCLUSION: There was a biphasic change in GCF leptin concentration during one cycle of orthodontic force application. There was a positive correlation between the GCF leptin concentration and rate of tooth movement.