Antimicrobial resistance; Bacterial genetics and epidemiology
26
Scopus Publications
1445
Scholar Citations
17
Scholar h-index
23
Scholar i10-index
Scopus Publications
Bacterial Cellulose Hydrogel Incorporating Silver Nanoparticles: A Nanobiotechnological Approach for Skin Infections Caused by MRSA and MRSE David N. Oliveira, Lara L. Oliveira, Hanne L. R. Q. Macedo, Yolice P. M. Ruiz, André Galembeck, et al. Pharmaceuticals, 2026 Background: Healthcare-associated infections (HAIs) caused by biofilm-forming Staphylococcus aureus and Staphylococcus epidermidis represent a major public health challenge due to their high resistance and involvement in skin, wound, and soft-tissue infections. In this context, silver nanoparticles (AgNPs) incorporated into Gluconacetobacter sp. bacterial cellulose hydrogel emerge as a promising alternative therapeutic strategy. Methods: AgNPs and hydrogels were synthesized and characterized using physicochemical and morphological analyses. Antibacterial activity was assessed by determining the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) following CLSI guidelines, as well as by time–kill curve assays. Antibiofilm activity was evaluated through the determination of minimum biofilm inhibitory concentration (MBIC) and minimum biofilm eradication concentration (MBEC) using crystal violet staining, complemented by scanning electron microscopy (SEM) and Congo red agar method. Results: The hydrogel exhibited a three-dimensional microfibrillar structure characteristic of bacterial cellulose, while AgNPs showed rod-shaped, oval, and triangular morphologies, with particle sizes of 35 and 59 nm and positive zeta potentials. MIC and MBC values ranged from 6.25 to 50 µg/mL across all tested formulations and strains. Time–kill assays demonstrated significant bacterial population reductions after 6 to 9 h of exposure. MBIC values ranged from 0.78 to 50 µg/mL, whereas MBEC values ranged from 1.56 to >100 µg/mL. SEM analyses confirmed biofilm disruption, cell eradication, and a reduction in extracellular polysaccharides, particularly for AgNPs incorporated into the hydrogel. Conclusions: Overall, the results highlight the strong antibacterial and enhanced antibiofilm potential of AgNP-loaded bacterial cellulose hydrogel against S. aureus and S. epidermidis, supporting its potential application in infection treatment.
Antibacterial and Antibiofilm Potential of Bacterial Cellulose Hydrogel Containing Vancomycin against Multidrug-Resistant Staphylococcus aureus and Staphylococcus epidermidis Ana Alice Venancio Correia, Luís André de Almeida Campos, Hanne Lazla Rafael de Queiroz Macêdo, Davi de Lacerda Coriolano, Maria Anndressa Alves Agreles, et al. Biology, 2024 The present study aimed to evaluate the in vitro antibacterial and antibiofilm activity of bacterial cellulose hydrogel produced by Zoogloea sp. (HYDROGEL) containing vancomycin (VAN) against bacterial strains that cause wound infections, such as multidrug-resistant (MDR) Staphylococcus aureus and Staphylococcus epidermidis. Initially, HYDROGEL was obtained from sugar cane molasses, and scanning electron microscopy (SEM) was performed to determine morphological characteristics. Then, VAN was incorporated into HYDROGEL (VAN-HYDROGEL). The antibacterial activity of VAN, HYDROGEL, and VAN-HYDROGEL was assessed using the broth microdilution method to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) against methicillin-sensitive S. aureus (MSSA) ATCC 25923, methicillin-resistant S. aureus (MRSA) ATCC 33591, S. epidermidis INCQS 00016 (ATCC 12228), five clinical isolates of MRSA, and nine clinical isolates of methicillin-resistant S. epidermidis, following the Clinical and Laboratory Standards Institute (CLSI) guidelines. Additionally, the antibacterial activity of VAN, HYDROGEL, and VAN-HYDROGEL was studied using the time-kill assay. Subsequently, the antibiofilm activity of VAN, HYDROGEL, and VAN-HYDROGEL was evaluated using crystal violet and Congo red methods, as well as SEM analysis. VAN and VAN-HYDROGEL showed bacteriostatic and bactericidal activity against MRSA and methicillin-resistant S. epidermidis strains. HYDROGEL did not show any antibacterial activity. Analysis of the time-kill assay indicated that HYDROGEL maintained the antibacterial efficacy of VAN, highlighting its efficiency as a promising carrier. Regarding antibiofilm activity, VAN and HYDROGEL inhibited biofilm formation but did not demonstrate biofilm eradication activity against methicillin-resistant S. aureus and S. epidermidis strains. However, it was observed that the biofilm eradication potential of VAN was enhanced after incorporation into HYDROGEL, a result also proven through images obtained by SEM. From the methods carried out in this study, it was possible to observe that HYDROGEL preserved the antibacterial activity of vancomycin, aside from exhibiting antibiofilm activity and enhancing the antibiofilm effect of VAN. In conclusion, this study demonstrated the potential of HYDROGEL as a candidate and/or vehicle for antibiotics against MDR bacteria that cause wound infections.
High prevalence of GR2 and GR4 plasmids in Acinetobacter baumannii strains from Brazil Beatriz Souza Toscano de Melo, Danilo Elias Xavier, Nilma Cintra Leal, Túlio de Lima Campos Pathogens and Disease, 2023 Acinetobacter baumannii is Gram-negative pathogen with extensive role in healthcare-associated infections (HAIs). Plasmids in this species are important carriers of antimicrobial resistance genes. In this work, we investigated the plasmids of 227 Brazilian A. baumannii genomes. A total of 389 plasmid sequences with 424 Rep proteins typed to 22 different homology groups (GRs) were identified. The GR2 plasmid group was the most predominant (40.6%), followed by the GR4 group (16.7%), representing ∼57% of all plasmids. There is a wide distribution of plasmids among the isolates and most strains carry more than one plasmid. Our analyses revealed a significant prevalence of GR4 plasmids in Brazilian A. baumannii genomes carrying several antimicrobial resistance genes, notably to carbapenem (39.43%). These plasmids harbor a MOBQ relaxase that might confer increased spreading potential in the environment. Most plasmids of the predominant groups belong to the same plasmid taxonomic unit (PTU-Pse7) and have a AbkA/AbkB toxin–antitoxin system that has a role in plasmid stability and dissemination of carbapenem resistance genes. The results of this work should contribute to our understanding of the molecular content of plasmids in a large and populous country, highlighting the importance of genomics for enhanced epidemiological surveillance.
Diverse and emerging molecular mechanisms award polymyxins resistance to Enterobacteriaceae clinical isolates from a tertiary hospital of Recife, Brazil Igor Vasconcelos Rocha, Natally dos Santos Silva, Carlos Alberto das Neves Andrade, Cláudia Fernanda de Lacerda Vidal, Nilma Cintra Leal, et al. Infection Genetics and Evolution, 2020 OBJECTIVES To describe the molecular mechanisms of polymyxins resistance in five Enterobacteriaceae clinical isolates in a tertiary hospital from Recife, Brazil. METHODS The species identification and the susceptibility to antimicrobials were firstly performed by automatized methods and polymyxin resistance was confirmed by broth microdilution methods. The genetic basis of resistance was characterized with WGS analyses to study their resistome, plasmidome and mobilome, by BLAST searches on reference databases. RESULTS Five (5%) Enterobacteriaceae isolates, comprising Escherichia coli (n = 2), Klebsiella pneumoniae (n = 2) and Citrobacter freundii (n = 1) species, exhibit polymyxin resistance. The mcr-1.1 gene was found in identical IncX4-plasmids harbored by both K. pneumoniae C119 (PolB MIC = 512 mg/L) and E. coli C153 (PolB MIC = 8 mg/L). The remaining E. coli strain C027 harbored the mcr-5.1 gene on an undefined Inc-plasmid (PolB MIC 256 mg/L). Some amino acid substitutions in PmrA (S29G, G144S), PmrB (S202P; D283G, W350*, Y258N) and PhoP (I44L) was detected among the E. coli clinical isolates, however they were also found in colistin-susceptible strains and predicted as neutral alterations. The mgrB of the ST54 KPC-2-producing K. pneumoniae C151 (PolB MIC = 32 g/mL) was interrupted at 69 nt by the IS903 element. The ST117 C. freundii C156 (PolB MIC = 256 mg/L) showed the A91T substitution on HAMP domain of the histidine kinase sensor CrrB, predicted as deleterious and deemed the remarkable determinant to polymyxins resistance in this strain. CONCLUSION Diverse mechanisms of polymyxins resistance were identified among clinical Enterobacteriaceae from a tertiary hospital of Recife, Brazil, such as plasmid-mediated MCR-1 and MCR-5; IS903-interruption of mgrB and mutation in CrrAB regulatory system. These findings highlight the involvement of the identified plasmids on mcr dissemination among Enterobacteriaceae; warn about co-selection of the polymyxin-resistant and KPC-producer K. pneumoniae ΔmgrB lineage by carbapenems usage; and demonstrate potential role of CrrAB on emerging of polymyxin resistance among Enterobacteriaceae, besides Klebsiella genera.
Comparative Genomics of Acinetobacter baumannii Clinical Strains From Brazil Reveals Polyclonal Dissemination and Selective Exchange of Mobile Genetic Elements Associated With Resistance Genes Nilma C. Leal, Túlio L. Campos, Antonio M. Rezende, Cássia Docena, Carina L. Mendes-Marques, et al. Frontiers in Microbiology, 2020 Acinetobacter baumannii is an opportunistic bacterial pathogen infecting immunocompromised patients and has gained attention worldwide due to its increased antimicrobial resistance. Here, we report a comparative whole-genome sequencing and analysis coupled with an assessment of antibiotic resistance of 46 Acinetobacter strains (45 A. baumannii plus one Acinetobacter nosocomialis) originated from five hospitals from the city of Recife, Brazil, between 2010 and 2014. An average of 3,809 genes were identified per genome, although only 2,006 genes were single copy orthologs or core genes conserved across all sequenced strains, with an average of 42 new genes found per strain. We evaluated genetic distance through a phylogenetic analysis and MLST as well as the presence of antibiotic resistance genes, virulence markers and mobile genetic elements (MGE). The phylogenetic analysis recovered distinct monophyletic A. baumannii groups corresponding to five known (ST1, ST15, ST25, ST79, and ST113) and one novel ST (ST881, related to ST1). A large number of ST specific genes were found, with the ST79 strains having the largest number of genes in common that were missing from the other STs. Multiple genes associated with resistance to β-lactams, aminoglycosides and other antibiotics were found. Some of those were clearly mapped to defined MGEs and an analysis of those revealed known elements as well as a novel Tn7-Tn3 transposon with a clear ST specific distribution. An association of selected resistance/virulence markers with specific STs was indeed observed, as well as the recent spread of the OXA-253 carbapenemase encoding gene. Virulence genes associated with the synthesis of the capsular antigens were noticeably more variable in the ST113 and ST79 strains. Indeed, several resistance and virulence genes were common to the ST79 and ST113 strains only, despite a greater genetic distance between them, suggesting common means of genetic exchange. Our comparative analysis reveals the spread of multiple STs and the genomic plasticity of A. baumannii from different hospitals in a single metropolitan area. It also highlights differences in the spread of resistance markers and other MGEs between the investigated STs, impacting on the monitoring and treatment of Acinetobacter in the ongoing and future outbreaks.
Occurrence of methicillin-resistant staphylococcus aureus in ready-to-eat raw fish from Japanese Cuisine Restaurants in Salvador, Brazil JOELZA SILVA CARVALHO, ANTENOR FERREIRA LEAL NETO, ISABELA MACIEL MELO, LUANA MILEN VARJÃO, CARLOS ALBERTO DAS NEVES ANDRADE, et al. Journal of Food Protection, 2020 The presence of methicillin-resistant Staphylococcus aureus (MRSA) strains in food products is a major issue for food safety. The present study was conducted to evaluate the occurrence and antimicrobial resistance profile of S. aureus, focusing on MRSA isolates, in ready-to-eat sashimi from Japanese restaurants in Salvador, Brazil. A total of 127 sashimi samples were collected directly from the take-out service in 16 restaurants. The staphylococcal isolates were identified morphologically and biochemically with standard laboratory procedures. S. aureus isolates were tested with a disk diffusion assay against seven antibiotics, and the cefoxitin and oxacillin were used to identify MRSA strains. Isolates with the MRSA phenotype were confirmed with a PCR assay. S. aureus was found in 73% of the sashimi samples, including sashimi from tuna (75.5% of samples) and salmon (72.5% of samples). Among those positive samples, 37% were contaminated with MRSA strains, found among 38.8% of salmon sashimi and 34.0% of tuna sashimi. Penicillin resistance was the most common type of antimicrobial resistance, found in 65.5% of the sashimi samples, followed by resistance to tetracycline (22.5%), erythromycin (16.0%), and ciprofloxacin (3.2%). Only two S. aureus isolates collected from different fish samples and restaurants had presumed resistance to vancomycin. The high prevalence of S. aureus and MRSA in these sashimi samples indicates a potential risk for foodborne disease, especially MRSA, spreading in the community. HIGHLIGHTS
Rapid detection of echinocandins resistance by MALDI-TOF MS in Candida parapsilosis complex Ana Emília M. Roberto, Danilo E. Xavier, Esteban E. Vidal, Cláudia Fernanda de L. Vidal, Rejane P. Neves, et al. Microorganisms, 2020 Mass spectrometry by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) was used to identify and differentiate the pattern of susceptibility of clinical isolates of Candida parapsilosis complex. 17 C. parapsilosis sensu stricto, 2 C. orthopsilosis, and 1 C. metapsilosis strains were obtained from blood cultures, and three different inocula (103, 105, and 107 CFU/mL) were evaluated against three echinocandins at concentrations ranging from 0.03 to 16 µg/mL after incubation of 1 h, 2 h, and 3 h. Drug-free control was used. The spectra obtained at these concentrations were applied to generate composite correlation index (CCI) matrices for each yeast individually. After cross correlations and autocorrelations of each spectra with null (zero) and maximal (16) concentrations, the CCI was used as separation parameter among spectra. Incubation time and inoculum were critical factors to reach higher precision and reliability of this trial. With an incubation time of 3 h and inoculum of 107 CFU/mL, it was possible to determine the breakpoint of the clinical yeasts by MALDI-TOF that presented high agreement with the clinical laboratory standard institute (CLSI) reference method. Herein, we show that mass spectrometry using the MALDI-TOF technique is powerful when it exploits antifungal susceptibility testing assays.
Bacterial Cellulose Hydrogel Incorporating Silver Nanoparticles: A Nanobiotechnological Approach for Skin Infections Caused by MRSA and MRSE DN Oliveira, LL Oliveira, HLRQ Macedo, YPM Ruiz, A Galembeck, ... Pharmaceuticals 19 (3), 409 , 2026 2026 Citations: 2
Antibacterial and antibiofilm potential of bacterial cellulose hydrogel containing vancomycin against multidrug-resistant Staphylococcus aureus and Staphylococcus epidermidis AAV Correia, LA de Almeida Campos, HLR de Queiroz Macêdo, ... Biology 13 (5), 354 , 2024 2024 Citations: 20
Characterization of vancomycin resistance mechanisms in Enterococcus faecium isolates from a Brazilian tertiary hospital IV Rocha, CAN de Andrade, AM Saraiva, EDG da Fonsêca, DE Xavier, ... Revista de Epidemiologia e Controle de Infecção 14 (2), 335-341 , 2024 2024 Citations: 1
Description of a new non- Tn 4401 element (NTE KPC -IIe) harboured on IncQ plasmid in Citrobacter werkmanii from recreational coastal water (vol 29, pg 207 … EH Campana, GB Kraychete, LF Montezzi, DE Xavier, RC Picao JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE 34, 271-271 , 2023 2023 Citations: 1
Corrigendum to ‘Description of a new non-Tn4401 element (NTEKPC-IIe) harboured on IncQ plasmid in Citrobacter werkmanii from recreational coastal water’[Journal of Global … EH Campana, GB Kraychete, LF Montezzi, DE Xavier, RC Picão Journal of Global Antimicrobial Resistance 34, 271 , 2023 2023
High prevalence of GR2 and GR4 plasmids in Acinetobacter baumannii strains from Brazil BST de Melo, DE Xavier, NC Leal, TL Campos Pathogens and Disease 81, ftad022 , 2023 2023 Citations: 1
An update on the role of Hfq RNA Chaperone in resistance and virulence of Acinetobacter baumannii LCA Silva, NC Leal, DE Xavier Revista Prevenção de Infecção e Saúde 8 (1) , 2022 2022
Description of a new non-Tn4401 element (NTEKPC-IIe) harboured on IncQ plasmid in Citrobacter werkmanii from recreational coastal water EH Campana, GB Kraychete, LF Montezzi, DE Xavier, RC Picão Journal of Global Antimicrobial Resistance 29, 207-211 , 2022 2022 Citations: 13
Genomic insights of Acinetobacter baumannii ST374 reveal wide and increasing resistome and virulome NH Fedrigo, DE Xavier, L Cerdeira, B Fuga, PVB Marini, DR Shinohara, ... Infection, Genetics and Evolution 97, 105148 , 2022 2022 Citations: 14
Epidemiological profile and detection of resistance genes in bloodstream infection in cancer patients: High occurrence of metallo-β-lactamases in Enterobacteriales C Soares, CP Inácio, MJB Silva, NC Leal, DE Xavier, V Magalhães, ... 2021 Citations: 1
Resistance Genes SC Ramírez, M Hamidian, R Zarrilli, OP de-Melo-Neto, NC Leal, ... Genomic Basis of Antibiotic Resistance and Virulence in Acinetobacter, 1176661 , 2021 2021
Diverse and emerging molecular mechanisms award polymyxins resistance to Enterobacteriaceae clinical isolates from a tertiary hospital of Recife, Brazil IV Rocha, N dos Santos Silva, CA das Neves Andrade, ... Infection, Genetics and Evolution 85, 104584 , 2020 2020 Citations: 13
Comparative Genomics of Acinetobacter baumannii Clinical Strains From Brazil Reveals Polyclonal Dissemination and Selective Exchange of Mobile Genetic … NC Leal, TL Campos, AM Rezende, C Docena, CL Mendes-Marques, ... Frontiers in Microbiology 11, 1176 , 2020 2020 Citations: 54
Occurrence of methicillin-resistant Staphylococcus aureus in ready-to-eat raw fish from Japanese cuisine restaurants in Salvador, Brazil JS Carvalho, AFL Neto, IM Melo, LM Varjao, CADN Andrade, DE Xavier, ... Journal of food protection 83 (6), 991-995 , 2020 2020 Citations: 17
Rapid Detection of Echinocandins Resistance by MALDI-TOF MS in Candida parapsilosis Complex AEM Roberto, DE Xavier, EE Vidal, CFL Vidal, RP Neves, RG Lima-Neto Microorganisms 8 (1), 109 , 2020 2020 Citations: 33
A novel plasmid-encoded mcr-4.3 gene in a colistin-resistant Acinetobacter baumannii clinical strain N Martins-Sorenson, E Snesrud, DE Xavier, LC Cacci, AT Iavarone, ... Journal of Antimicrobial Chemotherapy 75 (1), 60-64 , 2020 2020 Citations: 111
High-resolution genome-wide analysis is essential for the identification of ambiguous Aeromonas strains BST de Melo, CL Mendes-Marques, TL Campos, AMP Almeida, NC Leal, ... FEMS microbiology letters 366 (21), fnz245 , 2019 2019 Citations: 8
Multidrug-resistant Acinetobacter baumannii clones persist on hospital inanimate surfaces IV Rocha, DE Xavier, KRH Almeida, SR Oliveira, NC Leal Brazilian Journal of Infectious Diseases 22 (5), 438-441 , 2018 2018 Citations: 53
Staphylococcus spp. resistant in blood cultures and hospital surfaces and the patient safety KR Henrique de Almeida, NS Silva, IV Rocha, DE Xavier, NC Lea, ... REVISTA DE EPIDEMIOLOGIA E CONTROLE DE INFECCAO 7 (4) , 2017 2017 Citations: 3
Ciprofloxacin-resistant and extended-spectrum β-lactamase-producing Escherichia coli ST410 strain carrying the mcr-1 gene associated with bloodstream infection IV Rocha, CA das Neves Andrade, T de Lima Campos, AM Rezende, ... International journal of antimicrobial agents 49 (5), 655-656 , 2017 2017 Citations: 27
MOST CITED SCHOLAR PUBLICATIONS
Cloverleaf test (modified Hodge test) for detecting carbapenemase production in Klebsiella pneumoniae : be aware of false positive results CG Carvalhaes, RC Picao, AG Nicoletti, DE Xavier, AC Gales Journal of antimicrobial chemotherapy 65 (2), 249-251 , 2010 2010 Citations: 310
Efflux pumps expression and its association with porin down-regulation and β-lactamase production among Pseudomonas aeruginosa causing bloodstream … DE Xavier, RC Picão, R Girardello, LCC Fehlberg, AC Gales BMC microbiology 10 (1), 217 , 2010 2010 Citations: 188
Identification of Lactic Acid Bacteria in Fruit Pulp Processing Byproducts and Potential Probiotic Properties of Selected Lactobacillus Strains EF Garcia, WA Luciano, DE Xavier, WCA da Costa, K de Sousa Oliveira, ... Frontiers in microbiology 7, 1371 , 2016 2016 Citations: 176
Comparative analysis of the complete genome of KPC-2-producing Klebsiella pneumoniae Kp13 reveals remarkable genome plasticity and a wide repertoire of … PIP Ramos, RC Picão, LGP de Almeida, NCB Lima, R Girardello, ... BMC genomics 15 (1), 54 , 2014 2014 Citations: 140
A novel plasmid-encoded mcr-4.3 gene in a colistin-resistant Acinetobacter baumannii clinical strain N Martins-Sorenson, E Snesrud, DE Xavier, LC Cacci, AT Iavarone, ... Journal of Antimicrobial Chemotherapy 75 (1), 60-64 , 2020 2020 Citations: 111
Comparative Genomics of Acinetobacter baumannii Clinical Strains From Brazil Reveals Polyclonal Dissemination and Selective Exchange of Mobile Genetic … NC Leal, TL Campos, AM Rezende, C Docena, CL Mendes-Marques, ... Frontiers in Microbiology 11, 1176 , 2020 2020 Citations: 54
Multidrug-resistant Acinetobacter baumannii clones persist on hospital inanimate surfaces IV Rocha, DE Xavier, KRH Almeida, SR Oliveira, NC Leal Brazilian Journal of Infectious Diseases 22 (5), 438-441 , 2018 2018 Citations: 53
Carbapenem-resistant and cephalosporin-susceptible: a worrisome phenotype among Pseudomonas aeruginosa clinical isolates in Brazil EH Campana, DE Xavier, FVB Petrolini, JR Cordeiro-Moura, ... The Brazilian Journal of Infectious Diseases 21 (1), 57-62 , 2017 2017 Citations: 51
Metallo-β-lactamase-production in meropenem-susceptible Pseudomonas aeruginosa isolates: risk for silent spread RC Picão, FE Carrara-Marroni, AC Gales, EJ Venâncio, DE Xavier, ... Memórias do Instituto Oswaldo Cruz 107 (6), 747-751 , 2012 2012 Citations: 35
Rapid Detection of Echinocandins Resistance by MALDI-TOF MS in Candida parapsilosis Complex AEM Roberto, DE Xavier, EE Vidal, CFL Vidal, RP Neves, RG Lima-Neto Microorganisms 8 (1), 109 , 2020 2020 Citations: 33
Beta-Lactam Resistance Mechanisms in Pseudomonas aeruginosa Strains Causing Bloodstream Infections: Comparative Results Between Brazilian and American … LCC Fehlberg, DE Xavier, PP Peraro, AR Marra, MB Edmond, AC Gales Microbial Drug Resistance 18 (4), 402-407 , 2012 2012 Citations: 30
Antimicrobial activity of doripenem against Gram-negative pathogens: results from INVITA-A-DORI Brazilian study AC Gales, HD Azevedo, RF Cereda, R Girardello, DE Xavier, ... The Brazilian Journal of Infectious Diseases 15 (6), 513-520 , 2011 2011 Citations: 29
Ciprofloxacin-resistant and extended-spectrum β-lactamase-producing Escherichia coli ST410 strain carrying the mcr-1 gene associated with bloodstream infection IV Rocha, CA das Neves Andrade, T de Lima Campos, AM Rezende, ... International journal of antimicrobial agents 49 (5), 655-656 , 2017 2017 Citations: 27
Determinação da produção de metalo-beta-lactamases em amostras de Pseudomonas aeruginosa isoladas em João Pessoa, Paraíba L Santos Filho, IB Santos, AML Assis, DE Xavier Jornal Brasileiro de Patologia e Medicina Laboratorial 38, 291-296 , 2002 2002 Citations: 26
Identification of lactic acid bacteria in fruit pulp processing byproducts and potential probiotic properties of selected Lactobacillus strains. Front Microbiol 7: 1371 EF Garcia, WA Luciano, DE Xavier, WCA Da Costa, K de Sousa Oliveira, ... 2016 Citations: 22
Antibacterial and antibiofilm potential of bacterial cellulose hydrogel containing vancomycin against multidrug-resistant Staphylococcus aureus and Staphylococcus epidermidis AAV Correia, LA de Almeida Campos, HLR de Queiroz Macêdo, ... Biology 13 (5), 354 , 2024 2024 Citations: 20
Cepas de Pseudomonas spp. produtoras de metalo-betalactamase isoladas no Hospital Geral de Fortaleza JCN Torres, EA Menezes, MRF Ângelo, IRN Oliveira, MNC Salviano, ... Jornal Brasileiro de Patologia e Medicina Laboratorial 42 (5), 313-319 , 2006 2006 Citations: 20
Occurrence of methicillin-resistant Staphylococcus aureus in ready-to-eat raw fish from Japanese cuisine restaurants in Salvador, Brazil JS Carvalho, AFL Neto, IM Melo, LM Varjao, CADN Andrade, DE Xavier, ... Journal of food protection 83 (6), 991-995 , 2020 2020 Citations: 17
High frequency of OXA-253-producing Acinetobacter baumannii in different hospitals in Recife, Brazil FL de Sá Cavalcanti, CL Mendes-Marques, CRS Vasconcelos, ... Antimicrobial Agents and Chemotherapy 61 (1), 10.1128/aac. 01309-16 , 2017 2017 Citations: 15
Genomic insights of Acinetobacter baumannii ST374 reveal wide and increasing resistome and virulome NH Fedrigo, DE Xavier, L Cerdeira, B Fuga, PVB Marini, DR Shinohara, ... Infection, Genetics and Evolution 97, 105148 , 2022 2022 Citations: 14
