Татьяна Юрьевна

@sechenov.ru

Department of Propaedeutic of Childhood Diseases, Clinical Institute of Children's Health named after N.F. Filatov
I.M. Sechenov First Moscow State Medical University (Sechenov University)

Татьяна Юрьевна


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RESEARCH, TEACHING, or OTHER INTERESTS

Gastroenterology, Pediatrics, Perinatology and Child Health
9

Scopus Publications

Scopus Publications

  • Features of the duration of COVID-19 pneumonia in children under three months of age
    Anastasiia Bairashevskaia, A.I. Aminova, T.Yu. Eryushova, Б. О. Мацукатова, A.S. Pestova, et al.
    Voprosy Prakticheskoi Pediatrii, 2024
    COVID-19 infection remains an actual problem in pediatric practice today. Objective. To study the features of the course of this infection in newborns and infants. Patients and methods. A retrospective cohort study included 53 children under the age of 3 months with radiologically confirmed pneumonia. All children were divided into two groups: the main COV (32 children) with confirmed coronavirus infection, and the control NCOV (21 children) without this diagnosis. When analyzing clinical symptoms (runny nose, cough, fever, nausea, vomiting, weakness, lethargy, shortness of breath), it was not possible to establish statistically significant differences. A statistically significant was revealed when comparing the symptom of diarrhea (p = 0.015). Diarrhea could be explained by damage to the dense contacts of enterocytes. Results. Patients in the COV group had leukopenia with a t value of 9.6·109/l at+ normal values of neutrophils and lymphocytes. Lung lesions were not detected at high basophil values, which suggests a protective function of basophils in toddlers. Conclusion. COVID-19 coronavirus infection in children under 3 months has not yet been sufficiently studied and characterized by non-specific symptoms. To date, data on pathogenesis and clinical manifestations in this age group remain contradictory, which requires additional research. Key words: infants, diarrhea, COVID-19, newborns, pneumonia
  • Clinical observation of a patient with small and large intestine lesions with Crohn's disease and eosinophilic colitis
    I.S. Samolygo, , A.I. Aminova, S.I. Erdes, T.Yu. Eryushova, N.V. Davidenko, T.V. Zubova, , , , , , , and
    Voprosy Prakticheskoi Pediatrii, 2023
    Crohn's disease (granulomatous enteritis, granulomatous colitis, terminal ileitis) is a chronic relapsing disease characterized by transmural granulomatous inflammation with segmental lesions often of the small and large intestine. Eosinophilic colitis is a rare disease characterized by high level of eosinophilic infiltrate in the colon wall in patients with symptoms, more often manifested by abdominal pain or diarrhea. We face more often with the unique combination of these two diseases, characterized by different types of immunological reactions. We presented the clinical case of Crohn's disease and eosinophilic colitis in a 15-year-old boy. We face more often with the unique combination of these two pathological conditions, characterized by different types of immunological reactions, The article presents the clinical case of Crohn's disease and eosinophilic colitis in a 15-year-old boy. The aim of this clinical case is to increase the knowledge of practitioners about inflammatory bowel diseases, to point out possible combinations of different immunological inflammatory reactions in one patient, and the difficulties in diagnosing and managing this kind of patients. Key words: Crohn's disease, eosinophilic colitis, diagnosis, treatment, hormone-resistant form, targeted therapy, children
  • A clinical case. Tuberculous lymphadenitis in a 10-year-old girl: what should not be forgotten
    Alfiya I. Aminova, Л И Фельдфикс, Aliya I. Ibatullina, Tatiana Yu. Eryushova, Nigar N. Muradova, et al.
    Clinical Review for General Practice, 2023
    Tuberculosis is an infectious disease, with many forms and localizations, caused by Mycobacterium tuberculosis, which can affect any organs and tissues of the body. The paper presents a clinical case of tuberculosis of multiple locations, with the presence of resistance of M. tuberculosis to anti-tuberculosis drugs (moxifloxacin, amikacin, bedaquiline), manifesting with sluggish lymphadenopathy of the submandibular lymph nodes in a child who arrived in russia from Pakistan.
  • The relationship between the quality of life of medical students and their academic performance
    Zarnigar F. Gumbatova, Alfiya I. Aminova, Tatyana Yu. Eryushova, Susanna A. Guseva, Ekaterina I. Belova, Albina S. Pestova, Marina A. Manina
    Gigiena I Sanitariya, 2022
    Introduction. According to modern literature data, the quality of life of medical students is significantly lower than in the general population. Poor quality of life affects academic performance and can lead to rapid burnout. In this regard, an urgent problem is to study the practical significance of the impact of academic performance on the quality of life of students enrolled in medical universities, to improve their level of professional training. Materials and methods. With the help of the SF-36 questionnaire, 290 2nd year students of the pediatric faculty of the Medical University were examined. Students’ performance was assessed based on the results of an objective structured clinical examination (OSCE) and an average examination grade for 1-3 semesters. All students are divided into three groups - best, mediocres and worst. Results. For successful students, a high level of emotional state did not interfere with the performance of daily activities. The total physical component of health was the highest among average students. Students with poor academic performance had a minimal total mental health component, which indicated that they had depressive states and bad mood. It was found that the deterioration of academic performance led to a violation of the performance of daily activities, a sharp limitation of social contacts and the level of communication. A high level of academic performance correlated with low vital activity, increasing fatigue and disadaptation. Limitations. This study is limited to a selection of students studying at medical universities and undergoing an assessment of the quality of education with the help of OSCE. Conclusion. The quality of life, health status and academic performance of students are interdependent indicators. The use of questionnaires will reveal the reasons for the decline in working capacity associated with the deterioration in the quality of life.
  • Enteral feeding strategy for newborns with necrotizing enterocolitis
    A.I. Aminova, , P.A. Bobkova, E.I. Belova, N.V. Zaytseva, A.S. Antishin, Z.F. Gumbatova, T.Yu. Eryushova, Yu.L. Osovetskaya, , , , , , , and
    Voprosy Detskoi Dietologii, 2020
    Study objective. To optimize the recommendations on the strategy of enteral feeding for newborn babies with necrotizing enterocolitis (NEC). Patients and methods. A single-centre, observational, prospective, analytical, cohort study of 186 infants aged from 2 days to 2 months (96 boys, 90 girls) with the verified diagnosis of NEC of varied severity, who were treated at the neonatal pathology department of Moscow G.N.Speransky Children’s City Clinical Hospital No 9 in 2016-2018. The patients were divided into 2 groups, depending on disease staging according to the Walsh and Kliegman classification: group I – 124 (66.7%) newborns with mild NEC (stage 1A, B and 2A) and group II – 62 (33.3%) patients with a severe course (stages 2B and 3A, B). Results. As has been found, maternal risk factors for the development of severe forms of NEC in newborns are: maternal age over 40 years (OR = 1.40, 95% CI 0.83–2.17), assisted reproductive technologies (OR = 2.62, 95% CI 1.79–3.66), bad obstetrical-gynaecological history (OR = 1.80, 95% CI 1.03–2.97), infectious diseases during pregnancy (OR = 1.37, 95% CI 0.69–1.90). The ranking of the risk factors present in babies themselves permitted to find a causative relation with such factors as bacteriological contamination of biological media (OR = 2.80, 95% CI 1.3–4.0), bacteremia, viremia (OR = 5.80, 95% CI 2.99–7.13), gestational age 30–32 wks (OR = 2.35, 95% CI 1.01–3.94), which were significant only for mild forms of NEC. A minimal number of severe cases was diagnosed for a combination of breastfeeding and parenteral nutrition (16.7%), development of severe NEC was more often noted when feeding was started within 5 days: breastfeeding (26.3%), formula feeding (33.3 %), mixed breast and formula feeding (5%), or in infants who did not receive feeding due to their severe condition after birth (33%) (р < 0.05). The minimal number of severe NEC cases was found among babies who remained on breast (11.1%) and mixed (11.1%) feeding after the 5th day (р < 0.05), the maximal number – in infants who started from enteral feeding and were transferred to formula feeding (50%). Prolonged enteral feeding was three times more often associated with a severe course of NEC (р < 0.001). Conclusion. As has been found, the frequency of developing severe NEC depends on the character of the first feed after birth. A risk of developing severe forms of NEC decreases in newborns on breast- or mixed feeding, in combination of breast feeding and parenteral nutrition, short courses of enteral pauses, alternation of enteral feeding and enteral pauses. The results might be used in the clinical practice of neonatologists and paediatricians for prevention and management of NEC and its possible complications in newborn infants. Key words: necrotising enterocolitis, enteral pause, enteral nutrition, neonatology, birth weight, gestational age, premature infants
  • Challenges in diagnostics and management of atypical hemolytic uremic syndrome associated with acute intestinal infection in adolescent: Clinical case
    Tatiana Yu. Eryushova, Alfiia I. Aminova, Sofiia A. Lakhova, Zarnigar F. Gumbatova, Murat K. Astamirov, Olga Yu. Brunova
    Voprosy Sovremennoi Pediatrii Current Pediatrics, 2019
    Background. Acute intestinal infections (AII) caused by Shiga-like toxin-producing Escherichia coli and accompanied by hemolytic uremic syndrome (HUS) development are characterized by rapid progression and poor prognosis. Bloody diarrhea (hemorrhagic colitis) requires timely medical treatment both at young age and at adolescence. The severe course of HUS affected by AII caused by enterohaemorrhagic Escherichia coli requires additional medical attention and timely renal replacement therapy (hemodialysis). Clinical Case Description. The description and analysis of the severe course of HUS affected by AII in 14 years old adolescent girl is presented. There were some difficulties during diagnostics and thus the pathogenetic therapy onset was delayed. Differential diagnosis between typical and atypical HUS was performed. The disease was characterized by rapid progression of acute kidney injury, cerebrovascular disease and ischemia, multiple organ dysfunction syndrome and disseminated intravascular coagulation resulting in fatal case. Conclusion. Atypical HUS is the most frequent cause of multiple organ dysfunction syndrome alongside with acute kidney injury. The challenges of early diagnostics of atypical GUS in childhood are not fully solved nowadays and require additional attention of pediatricians. The clinical case of atypical GUS complicated by intestinal infection caused by enterohaemorrhagic Escherichia coli is described in this article. The severity of the disease course was due to the early manifestation of extrarenal symptoms and multiple organ failure.
  • Eosinophil cationic protein: Controversial issues of its diagnostic value in patients with allergic diseases
    G.D. Abdullaeva, , A.I. Aminova, Yu.V. Yudina, A.P. Prodeus, T.Yu. Eryushova, Z.F. Gumbatova, , , , , and
    Voprosy Prakticheskoi Pediatrii, 2019
  • On the role of intestinal microbiota in the development of food allergy from the positions of modern intestinal microbiology
    G.D. Abdullaeva, , A.I. Aminova, A.P. Prodeus, R.R. Kildiyarova, A.A. Korsunskiy, Yu.V. Yudina, Z.F. Gumbatova, T.Yu. Eryushova, , , , , , , and
    Voprosy Detskoi Dietologii, 2019
  • Necrotizing enterocolitis in a premature child with the polyetiological genesis of disease
    S.A. Lakhova, , A.I. Aminova, T.Yu. Eryushova, Z.F. Gumbatova, , , and
    Voprosy Prakticheskoi Pediatrii, 2018