Pro-resolving Annexin A1-derived peptide Ac2-26 reduces nociception and mitigates joint damage in experimental osteoarthritis Paula Lima Bosi, Amanda Dias Braga, Celso Martins Queiroz-Junior, Gabrielly Carvalho de Mattos, Vivian Louise Soares de Oliveira, et al. Inflammation Research, 2026 Objectives We investigated whether treatment with Annexin A1 (AnxA1) ameliorated joint nociception and tissue damage in an experimental osteoarthritis (OA) model. Design OA was induced by injection of collagenase into the tibiofemoral joint of wild-type (WT) and AnxA1-deficient male Balb/c mice. The control group received saline. Groups of WT mice were treated weekly with Ac2-26, an active peptide corresponding to the N-terminal region of AnxA1, in the affected joint. Mechanical nociception was analyzed weekly, and samples were collected 6 weeks after OA induction to analyze histopathology and markers of joint damage by qPCR and flow cytometry. Results The expression of Anxa1 is upregulated in the joints at the 1st and 3rd week and returned to the basal level at the 6th week after OA induction. AnxA1-deficient mice had persistent nociception and increased joint inflammation when compared to WT mice, although both groups had comparable cartilage damage. In WT mice, the treatment with Ac2-26 decreased joint nociception, tissue damage, and the expression of metalloproteinase-3 in the joint tissue. The collagenase injection increased the number of FAP + CD90 − fibroblast-like and CX3CR1 + macrophage-like synoviocytes expressing RANKL when compared to saline-injected mice. Treatment with Ac2-26 normalized the latter parameters. Conclusions AnxA1 and Ac2-26 are promising molecules that regulate key processes in OA, effectively mitigating tissue damage and dysfunction in a model of OA in mice.
PI3Kγ Pathway Contributes to Neuroinflammation and Neuronal Death Induced by Zika Virus Infection Danielle Cunha Teixeira, Gabriel Campolina‐Silva, Fernanda Martins Marim, Felipe Rocha da Silva Santos, Celso Martins Queiroz‐Junior, et al. Immunology, 2026 Zika virus (ZIKV) is an emerging arbovirus belonging to the Flaviviridae family and Orthoflavivirus genus, with a pronounced tropism for the central nervous system (CNS), where it induces neuroinflammation and neuronal death. ZIKV is known to exploit host cellular mechanisms, including the activation of survival pathways such as the PI3K/AKT signalling cascade, to evade apoptosis and enhance its replication. However, the role of the PI3Kγ isoform in ZIKV‐induced neuroinflammation has not been previously explored, and this study aimed to investigate PI3Kγ in ZIKV pathogenesis. Primary neuronal cultures from PI3Kγ‐deficient mice (PI3Kγ kd/kd ) and human neuroblastoma SH‐SY5Y cells treated with the PI3Kγ inhibitor AS605240 were infected with ZIKV to assess the impact of PI3Kγ signalling on viral replication and neuronal survival. Additionally, interferon α/β receptor knockout (A129) mice were treated with AS605240 either before or after ZIKV infection to evaluate the pathway's role in neuroinflammation. In vitro, both genetic ablation and pharmacological inhibition of PI3Kγ suppressed ZIKV replication (~3% and ~17%, respectively) and prevented neuronal death (~16%). In vivo, mice treated with the PI3Kγ inhibitor exhibited enhanced protection against ZIKV infection, characterised by reduced viral load (~12%) and diminished brain and optic nerve damage. This neuroprotective effect correlated with reduced TNF production (about ~67%) by microglia. Furthermore, inhibition of PI3Kγ curtailed the recruitment and activation of CD8+ T cells and decreased the production of pro‐inflammatory mediators, including IFN‐γ and IL‐17, in the brains of ZIKV‐infected mice. These findings suggest that PI3Kγ activation facilitates ZIKV infection and exacerbates neuroinflammation. Pharmacological inhibition of the PI3Kγ pathway may offer therapeutic benefits by limiting viral replication and alleviating neuroinflammatory responses during ZIKV infection.
Unveiling Clinical Phenotypes in Chronic Chikungunya Disease: Insights from a Brazilian Observational Study Karen Santos Lima, Adriane Paz Rocha, Alice Lanna Damásio Castro, Anna Carolina Faria Moreira Gomes Tavares, Flávia Patrícia Sena Teixeira Santos, et al. Tropical Medicine and Infectious Disease, 2026 Chronic chikungunya disease (CCD) affects approximately 30–50% of infected individuals and is associated with persistent inflammatory arthritis, chronic pain, and long-term functional disability. We conducted a prospective observational cohort study including 584 patients with laboratory-confirmed chikungunya infection, evaluated between 3 and 12 months after acute infection, to better understand the natural history, risk factors, clinical presentation, and treatment patterns of CCD. Here, we present a cross-sectional analysis derived from this cohort. Older age, female sex, and higher body mass index were identified as major risk factors for CCD. Four distinct clinical phenotypes were identified: Axial (12.2%), defined by inflammatory axial pain regardless of peripheral manifestations; Oligoarthritis (18.1%), defined by fewer than four swollen joints; Polyarthritis (10.6%), defined by four or more swollen joints; and Pain without Swelling (70.4%), characterized by myalgia and/or arthralgia in the absence of objective inflammatory findings on physical examination. The axial phenotype could overlap with peripheral phenotypes, whereas oligoarthritis, polyarthritis, and pain without swelling were mutually exclusive categories. These phenotypes differed substantially in symptom burden and clinical impact. Patients with the Pain without Swelling phenotype had longer symptom duration, whereas Axial and Polyarthritis phenotypes were associated with greater functional impairment and higher disease burden. These findings reinforce the clinical heterogeneity of CCD and support the potential value of phenotype-based approaches for clinical management and future therapeutic research.
Cyclodextrin-based delivery of Annexin A1 mimetic Ac2–26 enhances anti-inflammatory effect and prevents dengue-induced lethality combined with antiviral therapy Jenniffer Ramos Martins, Viviane Lima Batista, Laís Gomes Ramos, Celso Martins Queiroz‐Junior, Talita Cristina Martins da Fonseca, et al. British Journal of Pharmacology, 2026 Background and Purpose Severe dengue is characterised by systemic inflammation, cytokine storm, vascular leakage and haemorrhagic manifestations, largely driven by the host immune response to dengue virus (DENV) infection. Despite its burden, no licensed antivirals or host‐directed therapies are currently available. Our group has previously identified Annexin A1 (AnxA1) as an endogenous regulator of inflammation in dengue. Treatment with the AnxA1 peptidomimetic, Ac 2–26 , improved clinical outcomes in murine models of severe dengue by promoting resolution of inflammation without affecting viral control. Experimental Approach To explore new delivery strategies, we developed a novel formulation of Ac 2–26 complexed with hydroxypropyl‐β‐cyclodextrin (CDX‐Ac 2–26 ). Key Results In DENV‐2‐infected A129 mice, both intraperitoneal and oral CDX‐Ac 2–26 improved clinical scores and reversed thrombocytopenia. Notably, CDX‐Ac 2–26 reduced mast cell degranulation, MCPT‐1 plasma levels and CCL2 expression in spleen, with no effect on viral titres, indicating a host‐targeted mechanism and overcoming the anti‐inflammatory effects of the free peptide. Intraperitoneal administration achieved the same efficacy as oral dosing with only one‐third of the dose. Importantly, the combination of CDX‐Ac 2–26 with the antiviral nucleotide analogue sofosbuvir fully prevented disease and mortality in infected mice, highlighting a combinatorial effect between host‐directed and antiviral therapies. Conclusion and Implications These findings underscore the therapeutic potential of anti‐inflammatory/pro‐resolving strategies in severe dengue and support the development of CDX‐Ac 2–26 as a novel adjunctive treatment. Combining anti‐inflammatory and antiviral approaches may enhance efficacy and reduce treatment‐associated toxicity, offering a promising path for clinical translation.
Blood viral density dynamics in acute Chikungunya virus infection Eduardo C. Souza-Lima, Renan P. Souza, João V. R. Dutra, Fernando R. Ascencao, William H. K. Schilling, et al. Philosophical Transactions of the Royal Society of London Series B Biological Sciences, 2026 Chikungunya infection is caused by the Chikungunya alpha virus. The disease is characterized by an acute febrile illness that evolves to chronic, often severe, polyarticular limb arthralgia in approximately 30% of patients. There are no specific treatments for Chikungunya. To characterize the dynamics of viraemia in order to plan future antiviral studies, we took daily blood samples and evaluated serial viral densities measured by RT-PCR in a cohort of 19 adult Brazilian patients with acute Chikungunya infection. Viraemia exhibited a rapid decline, and most individuals were RT-PCR negative by day 4 after study entry. Higher viral loads were associated with earlier clinical presentations. Concentrations of sTNFR1 closely followed the decline in Chikungunya viral loads. Viral clearance measurements may be useful for the development and evaluation of novel treatments for Chikungunya infection. This article is part of the Theo Murphy meeting issue ‘Evaluating anti-infective drugs’.
Plasmin modulates neutrophilic inflammation and alveolar macrophage function, protecting mice from pneumococcal pneumonia Camila Cardoso, Antônio Felipe S. Carvalho, Edvaldo S. Lara, Fernanda S. Carneiro, Isabella Zaidan, et al. Blood, 2026 Accumulating evidence supports the proresolving actions of the plasminogen/plasmin (Plg/Pla) system during inflammation, beyond its classical role in fibrin degradation. Here, we investigated the role of Plg/Pla on key features of inflammation resolution in a murine model of severe pneumococcal pneumonia. High levels of Plg were observed in the airways after infection, accompanied by increased levels of Plg activator inhibitor-1, neutrophil elastase, and Plg degradation fragments as inflammation progressed. Pla treatment of mice infected with Streptococcus pneumoniae decreased neutrophilic infiltration in airways and lungs, accompanied by lower concentrations of the neutrophil chemoattractive chemokines CXCL1 and CXCL2 and the proinflammatory cytokines tumor necrosis factor, interleukin-6 (IL-6), and IL-1β. Pla treatment also enhanced neutrophil apoptosis and efferocytosis and slightly reduced bacterial loads in bronchoalveolar lavage. In addition, Pla decreased damage and fibrin deposition in the lungs, improving pneumonia-driven pulmonary mechanical dysfunction and rescuing mice from lethality. Pla-induced resolution of S pneumoniae–evoked inflammation was associated with neutrophil apoptosis, as the caspase-3–specific inhibitor Z-DEVD-FMK blocked Pla-protective actions. In addition to the effects on neutrophils, intranasal instillation of Pla in naive mice increased the number of alveolar macrophages and guided them toward a regulatory phenotype marked by enhanced efferocytosis of apoptotic neutrophils and increased bacterial phagocytosis, ultimately promoting host protection against pneumococcus-induced inflammation and tissue damage. In sum, our findings demonstrate that Pla modulates the lung inflammatory milieu and promotes key proresolving events, namely neutrophil apoptosis and expansion of alveolar macrophage with enhanced efferocytosis and phagocytic abilities, resulting in improved lung function and survival in pneumococcal pneumonia.
A brief overview of chikungunya-related pain William Antonio Gonçalves, Carla Daiane Ferreira de Sousa, Mauro Martins Teixeira, Daniele G. Souza European Journal of Pharmacology, 2025
The BJP expects authors to share data Christopher H. George, Stephen P.H. Alexander, Giuseppe Cirino, James R. Docherty, Daniel Hoyer, et al. British Journal of Pharmacology, 2019
Pro-resolving mediators William Antonio Gonçalves, Alesandra Côrte Reis Melão, Mauro Martins Teixeira, Barbara Maximino Rezende, Vanessa Pinho Immunopharmacology and Inflammation, 2018
Relevance of CCL3/CCR5 axis in oral carcinogenesis Janine Mayra da Silva, Tálita Pollyanna Moreira dos Santos, Lays Martin Sobral, Celso Martins Queiroz-Junior, Milene Alvarenga Rachid, et al. Oncotarget, 2017
Mas and Inflammation Lívia Corrêa Barroso, Kátia Daniella Silveira, Mauro Martins Teixeira, Ana Cristina Simões Silva Protective Arm of the Renin Angiotensin System Ras Functional Aspects and Therapeutic Implications, 2015
Soluble tumour necrosis factor receptor-1 (sTNFR1) levels are positively associated with exercise intensity in athletes after strenuous off-road cycling Journal of Sports Medicine and Physical Fitness, 2014
Influence of herpes viruses in the human periodontitis: The hypothesis of bacteria-virus synergy Current Trends in Periodontics and Implant Dentistry, 2013
Targeting CCL5 in inflammation Rafael Elias Marques, Rodrigo Guabiraba, Remo Castro Russo, Mauro Martins Teixeira Expert Opinion on Therapeutic Targets, 2013
Role of CCR2 in orthodontic tooth movement Silvana Rodrigues de Albuquerque Taddei, Ildeu Andrade, Celso Martins Queiroz-Junior, Thiago Pompermaier Garlet, Gustavo Pompermaier Garlet, et al. American Journal of Orthodontics and Dentofacial Orthopedics, 2012
[Inflammation in chronic kidney disease: the role of cytokines]. Heloisa R Vianna, Cristina Maria Bouissou Morais Soares, Marcelo S Tavares, Mauro Martins Teixeira, Ana Cristina Simoes e Silva Jornal Brasileiro De Nefrologia Orgao Oficial De Sociedades Brasileira E Latino Americana De Nefrologia, 2011
IL-33 induced Ag-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4 (Journal of Immunology (2008) 181, (4780-4790)) Journal of Immunology, 2009
Swim training suppresses tumor growth in mice Pedro William M. Almeida, Ary Gomes-Filho, Anderson J. Ferreira, Carlos Eduardo M. Rodrigues, Marco Fabrício Dias-Peixoto, et al. Journal of Applied Physiology, 2009
Increased serum levels of CCL11/eotaxin in schizophrenia Antonio Lucio Teixeira, Helton Jose Reis, Rodrigo Nicolato, Gustavo Brito-Melo, Humberto Correa, et al. Progress in Neuro Psychopharmacology and Biological Psychiatry, 2008
Six-minute walk test in Chagas cardiomyopathy Lidiane Sousa, Fernando Antônio Botoni, Raquel R. Britto, Manoel Otávio da Costa Rocha, Antonio Lúcio Teixeira, et al. International Journal of Cardiology, 2008
Response to an infectious insult (e.g., bacterial or fungal infection). Brazilian Journal of Medical and Biological Research Revista Brasileira De Pesquisas Medicas E Biologicas Sociedade Brasileira De Biofisica Et Al, 2001
Implementing a multi-centric cohort study during the SARS-CoV-2 pandemic in a resource-constrained setting: challenges, adaptive solutions, and lessons from Brazil LG Barberia, M de Almeida Roediger, RQ Gurgel, VS Santos, ... Archives of Public Health 84 (1), 72 , 2026 2026
The 2′-α-Fluoro, 2′-β-Bromo uridine phosphoramidate prodrug (2-BFU) reduces dengue virus replication and attenuates infection-induced thrombocytopenia In Vivo ASL Dias, FRS Santos, JR Martins, VL Batista, TCM da Fonseca, ... Medical Microbiology and Immunology 215 (1), 8 , 2026 2026
Pro-resolving Annexin A1-derived peptide Ac2-26 reduces nociception and mitigates joint damage in experimental osteoarthritis PL Bosi, AD Braga, CM Queiroz-Junior, GC de Mattos, VLS de Oliveira, ... Inflammation Research 75 (1), 69 , 2026 2026
PI3Kγ pathway contributes to neuroinflammation and neuronal death induced by Zika virus infection DC Teixeira, G Campolina‐Silva, FM Marim, FRS Santos, ... Immunology 178 (2), 318-335 , 2026 2026 Citations: 1
Unveiling Clinical Phenotypes in Chronic Chikungunya Disease: Insights from a Brazilian Observational Study KS Lima, AP Rocha, ALD Castro, ACFMG Tavares, FPST Santos, ... Tropical Medicine and Infectious Disease 11 (5), 140 , 2026 2026
Blood viral density dynamics in acute Chikungunya virus infection EC Souza-Lima, RP Souza, JVR Dutra, FR Ascencao, WHK Schilling, ... Philosophical Transactions of the Royal Society B: Biological Sciences 381 … , 2026 2026
Distal airway-specific condensation of saliva-free exhaled aerosols enables quantification of pulmonary SARS-CoV-2 RNA load in early COVID-19 J Henderson, T Mantso, S Ali, R Groß, JA Müller, A Wilkinson, L Usher, ... 2026
Protective effect of latex proteins from Plumeria pudica against acetaminophen-induced acute liver injury BDS Souza, ACS Sales, FDSDA Silva, GLDE Andrade, TFDE Souza, ... Anais da Academia Brasileira de Ciências 98 (1), e20240815 , 2026 2026
Distinct inflammatory biomarkers associated with rheumatological outcomes in chronic chikungunya disease LS Magalhães, JC Alves, RA de Lucena Couto Ócea, A Debbo, ... Scientific Reports , 2026 2026
Profound downregulation of neural transcription factor Npas4 and Nr4a family in fetal mice neurons infected with Zika virus SPA Lazcano, J Saliba, VV Costa, GH Campolina-Silva, FM Marim, ... Universidade Federal de Minas Gerais , 2026 2026
Neutrophil activity in sepsis: a systematic review CB de Resende Mascarenhas, IN Borges, W Gonçalves, RM Carneiro, ... Universidade Federal de Minas Gerais , 2026 2026
Understanding the relation between zika virus infection during pregnancy and adverse fetal, infant and child outcomes: a protocol for a systematic review and individual … AW Smith, Y Wei, TVB de Araújo, M VanKerkhove, CMT Martelli, ... Universidade Federal de Minas Gerais , 2026 2026
CAR T cells engineered via mRNA exhibit enhanced targeting of colorectal cancer W Nunes da Silva, PH Dias Moura Prazeres, MT Rodrigues Alves, ... Cancer Research 86 (7_Supplement), 459-459 , 2026 2026
Safety and immunogenicity of a live-attenuated chikungunya virus vaccine in adolescents: final results from a 12-month, double-blind, randomised, placebo-controlled, phase 3 … V Buerger, A Pfeiffer, P Schoengrundner, J Seebacher, R Hochreiter, ... The Lancet Infectious Diseases 26 (4), 417-428 , 2026 2026 Citations: 3
Core outcome measurement set for clinical trials in dengue: an international Delphi consensus study (DEN-CORE) S Yacoub, A Demidova, XHS Chan, A Ajam, D Baimukhambetova, A Horn, ... The Lancet Infectious Diseases 26 (4), e231-e244 , 2026 2026 Citations: 2
Unraveling SOCS-2 as a key mediator of beta-coronavirus infection pathogenesis and co-infection in chronic Chagas Disease CLN Barbosa, SLT Porto, R das Dores Pereira, NF de Melo Oliveira, ... Microbial Pathogenesis, 108457 , 2026 2026
Bridging the gap towards a novel antiviral therapeutic against dengue virus with major flavonoids from Scutellaria baicalensis P Hassandarvish, A Oo, BT Teoh, SS Sam, GOL Rodrigues, ... Antiviral Research, 106394 , 2026 2026
Long-term efficacy and safety of the single-dose tetravalent Butantan dengue vaccine EG Kallás, JA Moreira, EG Patiño, PE Braga, JCV Tenório, LBO Alves, ... Nature medicine, 1-8 , 2026 2026 Citations: 2
Imidazole Alkaloids Epiisopilosine and Epiisopiloturine Attenuate Acetaminophen‐Induced Liver Toxicity in Mice via Autophagy Modulation and Anti‐Inflammatory Effects AP de Oliveira, G Pacheco, ALF Lopes, AK da Silva Araujo, ... Journal of Biochemical and Molecular Toxicology 40 (3), e70782 , 2026 2026
Strength training modulates inflammation in pre-frail older women: involvement of Treg cells ELM Vieira, FM Coelho, S Rezaei, DS Pereira, CT Fagundes, JP Silva, ... Brain Behavior and Immunity Integrative, 100156 , 2026 2026
MOST CITED SCHOLAR PUBLICATIONS
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43 KM Maslowski, AT Vieira, A Ng, J Kranich, F Sierro, D Yu, HC Schilter, ... Nature 461 (7268), 1282-1286 , 2009 2009 Citations: 3838
Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome L Macia, J Tan, AT Vieira, K Leach, D Stanley, S Luong, M Maruya, ... Nature communications 6 (1), 6734 , 2015 2015 Citations: 1565
Experimental design and analysis and their reporting II: Updated and simplified guidance for authors and peer reviewers MJ Curtis, S Alexander, G Cirino, JR Docherty, CH George, MA Giembycz, ... British journal of pharmacology 175 (7), 987-993 , 2018 2018 Citations: 1472
ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020 E Lilley, SC Stanford, DE Kendall, SPH Alexander, G Cirino, JR Docherty, ... British Journal of pharmacology 177 (16), 3611 , 2020 2020 Citations: 1158
Resolution of inflammation: what controls its onset? MA Sugimoto, LP Sousa, V Pinho, M Perretti, MM Teixeira Frontiers in immunology 7, 160 , 2016 2016 Citations: 891
The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases RC Russo, CC Garcia, MM Teixeira, FA Amaral Expert review of clinical immunology 10 (5), 593-619 , 2014 2014 Citations: 844
Evolution and epidemic spread of SARS-CoV-2 in Brazil DS Candido, IM Claro, JG De Jesus, WM Souza, FRR Moreira, ... Science 369 (6508), 1255-1260 , 2020 2020 Citations: 752
IL-33 Induces Antigen-Specific IL-5 + T Cells and Promotes Allergic-Induced Airway Inflammation Independent of IL-4 M Kurowska-Stolarska, P Kewin, G Murphy, RC Russo, B Stolarski, ... The Journal of Immunology 181 (7), 4780-4790 , 2008 2008 Citations: 604
ACE2, angiotensin‐(1‐7) and M as receptor axis in inflammation and fibrosis AC Simões e Silva, KD Silveira, AJ Ferreira, MM Teixeira British journal of pharmacology 169 (3), 477-492 , 2013 2013 Citations: 585
Planning experiments: Updated guidance on experimental design and analysis and their reporting III MJ Curtis, SPH Alexander, G Cirino, CH George, DA Kendall, PA Insel, ... British Journal of Pharmacology 179 (15), 3907-3913 , 2022 2022 Citations: 542
Uric acid in chronic heart failure: a marker of chronic inflammation F Leyva, SD Anker, IF Godsland, M Teixeira, PG Hellewell, WJ Kox, ... European heart journal 19 (12), 1814-1822 , 1998 1998 Citations: 526
Cytokines and neurohormones relating to body composition alterations in the wasting syndrome of chronic heart failure SD Anker, PP Ponikowski, AL Clark, F Leyva, M Rauchhaus, M Kemp, ... European heart journal 20 (9), 683-693 , 1999 1999 Citations: 505
Targeting CCL5 in inflammation RE Marques, R Guabiraba, RC Russo, MM Teixeira Expert opinion on therapeutic targets 17 (12), 1439-1460 , 2013 2013 Citations: 472
Annexin A1 and the resolution of inflammation: modulation of neutrophil recruitment, apoptosis, and clearance MA Sugimoto, JP Vago, MM Teixeira, LP Sousa Journal of immunology research 2016 (1), 8239258 , 2016 2016 Citations: 461
Diagnosis and management of Chagas disease and cardiomyopathy AL Ribeiro, MP Nunes, MM Teixeira, MOC Rocha Nature Reviews Cardiology 9 (10), 576-589 , 2012 2012 Citations: 427
Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure PE Marques, SS Amaral, DA Pires, LL Nogueira, FM Soriani, BHF Lima, ... Hepatology 56 (5), 1971-1982 , 2012 2012 Citations: 407
The role of probiotics and prebiotics in inducing gut immunity AT Vieira, MM Teixeira, FS Martins Frontiers in immunology 4, 445 , 2013 2013 Citations: 395
Commensal microbiota is fundamental for the development of inflammatory pain FA Amaral, D Sachs, VV Costa, CT Fagundes, D Cisalpino, TM Cunha, ... Proceedings of the National Academy of Sciences 105 (6), 2193-2197 , 2008 2008 Citations: 394
Crucial role of neutrophils in the development of mechanical inflammatory hypernociception TM Cunha, WA Verri, IR Schivo, MH Napimoga, CA Parada, S Poole, ... Journal of Leucocyte Biology 83 (4), 824-832 , 2008 2008 Citations: 386
Gut dysbiosis during influenza contributes to pulmonary pneumococcal superinfection through altered short-chain fatty acid production V Sencio, A Barthelemy, LP Tavares, MG Machado, D Soulard, C Cuinat, ... Cell reports 30 (9), 2934-2947. e6 , 2020 2020 Citations: 378