Joao Paulo Silva Nunes

@fz.org.br

Heart Institute, University of São Paulo
Fundação Zerbini



              

https://researchid.co/joaonunes

RESEARCH, TEACHING, or OTHER INTERESTS

General Biochemistry, Genetics and Molecular Biology, Immunology

432

Scholar Citations

10

Scholar h-index

10

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • In severe alcohol‐related hepatitis, acute kidney injury is prevalent, associated with mortality independent of liver disease severity, and can be predicted using IL‐8 and
    LD Tyson, S Atkinson, RW Hunter, M Allison, A Austin, JW Dear, E Forrest, ...
    Alimentary pharmacology & therapeutics 58 (11-12), 1217-1229 2023

  • Diretriz da SBC sobre Diagnstico e Tratamento de Pacientes com Cardiomiopatia da Doena de Chagas–2023
    JA Marin-Neto, A Rassi Jr, GMM Oliveira, LCL Correia, AN Ramos, ...
    Arquivos Brasileiros de Cardiologia 120 (6), e20230269 2023

  • Diretriz da Sociedade Brasileira de Cardiologia sobre diagnstico e tratamento de pacientes com cardiomiopatia da doena de Chagas
    JA Marin-Neto, A Rassi Jr, GMM Oliveira, LCL Correia, AN Ramos Jr, ...
    SciELO Preprints 2022

  • Blood DNA methylation marks discriminate Chagas cardiomyopathy disease clinical forms
    P Brochet, B Ianni, JPS Nunes, AF Frade, PC Teixeira, C Mady, ...
    Frontiers in Immunology 13, 1020572 2022

  • Chagas Disease Megaesophagus Patients Carrying Variant MRPS18B P260A Display Nitro-Oxidative Stress and Mitochondrial Dysfunction in Response to IFN-γ
    KDA Silva, JPS Nunes, P Andrieux, P Brochet, RR Almeida, ...
    Biomedicines 10 (9), 2215 2022

  • Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy
    P Brochet, BM Ianni, L Laugier, AF Frade, JP Silva Nunes, PC Teixeira, ...
    Frontiers in Immunology 13, 958200 2022

  • Incident acute kidney injury in severe alcohol-related hepatitis is strongly associated with mortality and can be predicted using micro-RNAs and markers of systemic inflammation
    LD Tyson, S Atkinson, M Allison, A Austin, L Cross, J Dear, E Forrest, ...
    Journal of Hepatology 77, S122 2022

  • Reduced T cell and antibody responses to inactivated coronavirus vaccine among individuals above 55 years old
    GX Medeiros, GL Sasahara, JY Magawa, JPS Nunes, FR Bruno, ...
    Frontiers in immunology 13, 812126 2022

  • Recurrence of COVID-19 associated with reduced T-cell responses in a monozygotic twin pair
    MV De Castro, KS Santos, JS Apostolico, ER Fernandes, RR Almeida, ...
    Open Biology 12 (2), 210240 2022

  • Guideline of the Brazilian Society of Cardiology on Diagnosis and Treatment of Patients with Chagas Disease Cardiomyopathy
    JA Marin-Neto, A Rassi Jr, GM Moraes Oliveira, LC Lemos Correia, ...
    Guideline of the Brazilian Society of Cardiology on Diagnosis and Treatment 2022

  • Prospecting of potentially probiotic lactic acid bacteria from bovine mammary ecosystem: imminent partners from bacteriotherapy against bovine mastitis
    RS Steinberg, LCS Silva, MR de Souza, RB Reis, AF Bicalho, JPS Nunes, ...
    International Microbiology, 1-18 2022

  • Specific methylation marks in promoter regions are associated to the pathogenic process of Chronic Chagas disease Cardiomyopathy by modifying transcription factor binding patterns
    P Brochet, B Ianni, L Laugier, AF Frade, JPS Nunes, PC Teixeira, C Mady, ...
    medRxiv, 2021.12. 20.21267972 2021

  • Mitochondria at the Crossroads of Immunity and Inflammatory Tissue Damage
    JPS Nunes, PM Moraes-Vieira, C Chevillard, E Cunha-Neto
    Frontiers in Immunology 12, 810787 2021

  • Impairment of multiple mitochondrial energy metabolism pathways in the heart of Chagas disease cardiomyopathy patients
    PC Teixeira, A Ducret, H Langen, E Nogoceke, RHB Santos, ...
    Frontiers in Immunology 12, 755782 2021

  • Co-exposure of cardiomyocytes to IFN-γ and TNF-α induces mitochondrial dysfunction and nitro-oxidative stress: implications for the pathogenesis of chronic chagas disease
    JPS Nunes, P Andrieux, P Brochet, RR Almeida, E Kitano, AK Honda, ...
    Frontiers in immunology 12, 755862 2021

  • Mitochondria as a cellular hub in infection and inflammation
    P Andrieux, C Chevillard, E Cunha-Neto, JPS Nunes
    International journal of molecular sciences 22 (21), 11338 2021

  • Rare pathogenic variants in mitochondrial and inflammation-associated genes may lead to inflammatory cardiomyopathy in Chagas disease
    M Ouarhache, S Marquet, AF Frade, AM Ferreira, B Ianni, RR Almeida, ...
    Journal of clinical immunology 41, 1048-1063 2021

  • Monozygotic twins discordant for severe clinical recurrence of COVID-19 show drastically distinct T cell responses to SARS-Cov-2
    MV Castro, KS Santos, JS Apostolico, ER Fernandes, RR Almeida, ...
    medRxiv, 2021.03. 26.21253645 2021

  • miRNAs may play a major role in the control of gene expression in key pathobiological processes in Chagas disease cardiomyopathy
    L Laugier, LRP Ferreira, FM Ferreira, S Cabantous, AF Frade, JP Nunes, ...
    PLoS neglected tropical diseases 14 (12), e0008889 2020

  • Disease tolerance and pathogen resistance genes may underlie Trypanosoma cruzi persistence and differential progression to Chagas disease cardiomyopathy
    C Chevillard, JPS Nunes, AF Frade, RR Almeida, RP Pandey, ...
    Frontiers in immunology 9, 411639 2018

MOST CITED SCHOLAR PUBLICATIONS

  • Mitochondria as a cellular hub in infection and inflammation
    P Andrieux, C Chevillard, E Cunha-Neto, JPS Nunes
    International journal of molecular sciences 22 (21), 11338 2021
    Citations: 122

  • Disease tolerance and pathogen resistance genes may underlie Trypanosoma cruzi persistence and differential progression to Chagas disease cardiomyopathy
    C Chevillard, JPS Nunes, AF Frade, RR Almeida, RP Pandey, ...
    Frontiers in immunology 9, 411639 2018
    Citations: 78

  • ImageJ macros for the user-friendly analysis of soft-agar and wound-healing assays
    JPS Nunes, AAM Dias
    BioTechniques 62 (4), 175-179 2017
    Citations: 50

  • miRNAs may play a major role in the control of gene expression in key pathobiological processes in Chagas disease cardiomyopathy
    L Laugier, LRP Ferreira, FM Ferreira, S Cabantous, AF Frade, JP Nunes, ...
    PLoS neglected tropical diseases 14 (12), e0008889 2020
    Citations: 35

  • Co-exposure of cardiomyocytes to IFN-γ and TNF-α induces mitochondrial dysfunction and nitro-oxidative stress: implications for the pathogenesis of chronic chagas disease
    JPS Nunes, P Andrieux, P Brochet, RR Almeida, E Kitano, AK Honda, ...
    Frontiers in immunology 12, 755862 2021
    Citations: 29

  • Long pentraxin 3-mediated fibroblast growth factor trapping impairs fibrosarcoma growth
    PF Rodrigues, S Matarazzo, F Maccarinelli, E Foglio, A Giacomini, ...
    Frontiers in oncology 8, 472 2018
    Citations: 26

  • Reduced T cell and antibody responses to inactivated coronavirus vaccine among individuals above 55 years old
    GX Medeiros, GL Sasahara, JY Magawa, JPS Nunes, FR Bruno, ...
    Frontiers in immunology 13, 812126 2022
    Citations: 24

  • Impairment of multiple mitochondrial energy metabolism pathways in the heart of Chagas disease cardiomyopathy patients
    PC Teixeira, A Ducret, H Langen, E Nogoceke, RHB Santos, ...
    Frontiers in Immunology 12, 755782 2021
    Citations: 14

  • Rare pathogenic variants in mitochondrial and inflammation-associated genes may lead to inflammatory cardiomyopathy in Chagas disease
    M Ouarhache, S Marquet, AF Frade, AM Ferreira, B Ianni, RR Almeida, ...
    Journal of clinical immunology 41, 1048-1063 2021
    Citations: 14

  • Prospecting of potentially probiotic lactic acid bacteria from bovine mammary ecosystem: imminent partners from bacteriotherapy against bovine mastitis
    RS Steinberg, LCS Silva, MR de Souza, RB Reis, AF Bicalho, JPS Nunes, ...
    International Microbiology, 1-18 2022
    Citations: 10

  • Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy
    P Brochet, BM Ianni, L Laugier, AF Frade, JP Silva Nunes, PC Teixeira, ...
    Frontiers in Immunology 13, 958200 2022
    Citations: 7

  • Recurrence of COVID-19 associated with reduced T-cell responses in a monozygotic twin pair
    MV De Castro, KS Santos, JS Apostolico, ER Fernandes, RR Almeida, ...
    Open Biology 12 (2), 210240 2022
    Citations: 5

  • Diretriz da SBC sobre Diagnstico e Tratamento de Pacientes com Cardiomiopatia da Doena de Chagas–2023
    JA Marin-Neto, A Rassi Jr, GMM Oliveira, LCL Correia, AN Ramos, ...
    Arquivos Brasileiros de Cardiologia 120 (6), e20230269 2023
    Citations: 4

  • In severe alcohol‐related hepatitis, acute kidney injury is prevalent, associated with mortality independent of liver disease severity, and can be predicted using IL‐8 and
    LD Tyson, S Atkinson, RW Hunter, M Allison, A Austin, JW Dear, E Forrest, ...
    Alimentary pharmacology & therapeutics 58 (11-12), 1217-1229 2023
    Citations: 3

  • Diretriz da Sociedade Brasileira de Cardiologia sobre diagnstico e tratamento de pacientes com cardiomiopatia da doena de Chagas
    JA Marin-Neto, A Rassi Jr, GMM Oliveira, LCL Correia, AN Ramos Jr, ...
    SciELO Preprints 2022
    Citations: 3

  • Chagas Disease Megaesophagus Patients Carrying Variant MRPS18B P260A Display Nitro-Oxidative Stress and Mitochondrial Dysfunction in Response to IFN-γ
    KDA Silva, JPS Nunes, P Andrieux, P Brochet, RR Almeida, ...
    Biomedicines 10 (9), 2215 2022
    Citations: 2

  • Guideline of the Brazilian Society of Cardiology on Diagnosis and Treatment of Patients with Chagas Disease Cardiomyopathy
    JA Marin-Neto, A Rassi Jr, GM Moraes Oliveira, LC Lemos Correia, ...
    Guideline of the Brazilian Society of Cardiology on Diagnosis and Treatment 2022
    Citations: 2

  • Monozygotic twins discordant for severe clinical recurrence of COVID-19 show drastically distinct T cell responses to SARS-Cov-2
    MV Castro, KS Santos, JS Apostolico, ER Fernandes, RR Almeida, ...
    medRxiv, 2021.03. 26.21253645 2021
    Citations: 2

  • Incident acute kidney injury in severe alcohol-related hepatitis is strongly associated with mortality and can be predicted using micro-RNAs and markers of systemic inflammation
    LD Tyson, S Atkinson, M Allison, A Austin, L Cross, J Dear, E Forrest, ...
    Journal of Hepatology 77, S122 2022
    Citations: 1

  • Mitochondria at the Crossroads of Immunity and Inflammatory Tissue Damage
    JPS Nunes, PM Moraes-Vieira, C Chevillard, E Cunha-Neto
    Frontiers in Immunology 12, 810787 2021
    Citations: 1