Adewale Oluropo OLATAYO

@westlanduniversity.edu.ng

Ag. Head of Department, biological sciences
Westland university, iwo, osun state

Adewale Oluropo OLATAYO


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https://researchid.co/adewale

RESEARCH, TEACHING, or OTHER INTERESTS

Microbiology, Waste Management and Disposal, Pharmacology, Toxicology and Pharmaceutics, Drug Discovery
4

Scopus Publications

Scopus Publications

  • Occurrence of Carbapenemase Resistance genes in hospital wastewater from selected facilities in Ibadan, Oyo State, Nigeria
    Omolola Adenike Ajayi-Odoko, Ayantade Dayo Victor Ayansina, Emmanuel Adewuni Akintunde, Iyinkristi Damilare Ayokunle, Wuraola Omolola Ibitoye, Adewale Oluropo Olatayo
    Scientific African, 2026
    The extensive misuse of antibiotics, insufficient wastewater treatment, and the direct release of hospital effluents into the environment in Nigeria contribute to the spread of clinically significant antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs). Consequently, continuous environmental bacteriological monitoring has become essential for producing trustworthy information regarding the prevalence and distribution of antimicrobial-resistant bacteria (ARB) and antimicrobial resistance genes (ARGs) in environmental matrices. This research was aimed at investigating carbapenemase resistance genes in Gram-negative bacteria isolated from selected hospital wastewaters in Ibadan, Nigeria. Selected resistance genes were screened for by Polymerase Chain Reaction (PCR) amplification using primers targeting the genes of interest. All fifty-four screened isolates were resistant to ceftazidime. Sulphamethoxazole trimethoprim, azithromycin, cefotaxime, oxacillin, and cefepime resistance percentages were 64.81 %, 74.07%, 59.26%, 53.70%, and 31.48%, respectively. Resistance to streptomycin was 77.78%, while resistance to ciprofloxacin and cefoxitin was 38.89% and 25.93%, respectively. Imipenem had the lowest percentage of resistance, 20.37 %. The bla VIM gene was one of the most common ARGs detected by PCR among the isolates, with a percentage frequency of 12.96 % (7/54), followed by bla NDM with a frequency of 3.7 % (2/54). The percentage frequency of bla IMP and bla KPC was both 1.85 % (1/54). In one of the Klebsiella species isolated, multiple resistance genes ( bla VIM, KPC, IMP ) were discovered. This study established the role of hospital wastewater on the proliferation of ARBs and ARGs outside of hospitals.
  • Parasitological and Bacteriological Evaluation of Common Raw Fruits Collected from Two Major Markets in Iwo, Osun State, South-West Nigeria
    Oladipo O. Oladosu, David O. Olatunde, Adewale O. Olatayo, Bukola Atobatele
    International Journal of Food Science, 2023
    Background. Fruits are a vital part of human nutrition because they contain the growth factors required to maintain normal health. Fruits are also known to harbour a wide range of parasites and bacteria. Consumption of unwashed raw fruits can lead to foodborne pathogens. This study was carried out to examine the presence of parasites and bacteria on fruits sold at two major markets in Iwo, Osun state, South-West Nigeria. Methods. Twelve different fresh fruits and seven different fresh fruits were purchased from different vendors from “Odo-ori” and “Adeeke” markets, respectively. The samples were transported to the microbiology laboratory of Bowen University, Iwo, Osun state for bacteriological and parasitological analysis. The parasites were concentrated by sedimentation and were examined using a light microscope, while for the microbial analysis, culturing and biochemical tests were also carried out on all the samples. Results. The parasites discovered include Fasciola hepatica eggs, Ascaris lumbricoides and Strongyloides stercoralis larvae, hookworm larvae, and Taenia and Trichuris trichiura eggs. Ascaris lumbricoides was most frequently detected (40.0%). Bacteria isolated from the sampled fruits include Klebsiella oxytoca, Klebsiella pneumoniae, Enterobacter aerogenes, Escherichia coli, Kluyvera ascorbata, Proteus mirabilis, Staphylococcus intermedius, Staphylococcus sp., Micrococcus sedentarius, Corynebacterium diphtheriae, and Streptococcus zooepidemicus. Conclusion. The presence of parasites and bacteria on the fruits observed indicates that public health diseases may arise from their consumption. Awareness and education among farmers, vendors, and consumers about the importance of personal and food hygiene through proper washing or disinfection of fruits could reduce the risk of parasites and bacterial fruit contamination.
  • Genotypic Characterization of Antibiotic-Resistant Genes in Gram Negative Bacteria Isolated from Selected Fish Ponds Effluents Samples within Oyo State
    Adewale O. Olatayo, Ayantade Dayo Victor Ayansina, Samuel Olatunde Dahunsi, Oluwabukola A. Oroye
    Tropical Journal of Natural Product Research, 2022
    Extended-spectrum beta-lactamase (ESBL) and carbapenem-resistant bacteria are becoming a rising global public health risk, with food products serving as distribution channels and aquatic ecosystems as prospective storage. The focus of this research therefore is to isolate antibiotics resistant Enterobacteriaceae from selected fish pond effluents in Oyo State. A total of 129 effluents were collected from 42 fish ponds and were cultivated on MacConkey agar. Bacteria were isolated and antibiotic susceptibility of the isolates to Gentamicin, imipenem, meropenem, tetracycline, and cefepime was determined using the disc diffusion method. MDR bacteria were checked for blaCTX-M, blaSHV, blaTEM, blaKPC, blaOXA, and blaNDM resistance genes using polymerase chain reaction (PCR), and isolate with resistance genes were characterized using 16S rRNA sequencing. Forty-six point five (46.5) percent of the 270 Enterobacteriaceae isolates obtained from effluent samples were resistant to imipenem, meropenem (45.7%), and tetracycline (39.4%), cefepime (35.8%), and gentamycin (19.2%). blaSHV was the sole gene found in 13.33 % of the isolates examined by polymerase chain reaction. The detection of ESBL and carbapenemase-producing gram-negative bacteria from selected fish ponds in this study is confirmed and represents a major public health problem. As a result, regular surveillance of antibiotic-resistant bacteria in fish ponds is required to aid disease control and better understand their public health implications.
  • Antibacterial Activity and Molecular Docking Analysis of the Stem Bark Extracts of Persea americana Mill (Lauraceae)
    Tropical Journal of Natural Product Research, 2022