YATI H VAIDYA
@sanppgi.ac.in/#
Assistant Professor, department of microbiology
SHRI A. N. PATEL POST GRADUATE INSTITUTE OF SCIENCE AND RESEARCH
RESEARCH, TEACHING, or OTHER INTERESTS
Biochemistry, Genetics and Molecular Biology, Applied Microbiology and Biotechnology, Biomaterials, Pharmacology (medical)
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Anjali B. Thakkar, R.B. Subramanian, Vasudev R. Thakkar, Sandip V. Bhatt, Sunil Chaki, Yati H. Vaidya, Vikas Patel, and Parth Thakor
Elsevier BV
Priteshkumar M. Thakor, Rajesh J. Patel, Ranjan Kr. Giri, Sunil H. Chaki, Ankurkumar J. Khimani, Yati H. Vaidya, Parth Thakor, Anjali B. Thakkar, and Jatin D. Patel
American Chemical Society (ACS)
R. U. Raval, D. B. Kapdi, N. H. Bhavsar, V. V. Surati, J. D. Solanki, S. R. Panjabi, P. M. Patel, Y. H. Vaidya, D. N. Verma, and K. P. Patel
Technoscience Publications
In view of the environmental problems generated by the large-scale production of fly ash, increasing attention is now being paid to the recycling of fly ash as a good source of nutrients. To reduce the cost of fly ash disposal and best utilization, it aimed to convert the fly ash into valuable vermicompost. Stated throughout the experiment, we opted for a soil sample and fly ash and pressed with different concentrations (control, 20%, 50%, 80% and 100%). Subsequently, all the mixtures were vermicomposted for 60 days by adding 100 Earthworms (Eisenia foetida) in each pile. The X-ray fluorescence spectroscopy measured the composition of the metal in fly ash as well as the nutritional content in the soil. This is followed by examining the morphological characteristics and cytogenetic study of Ricinus communis L. The present study indicated that E. foetida mitigates the toxicity of fly ash and is hence used as valuable vermicompost.
Sefali R. Patel, Sunil H. Chaki, Ranjan Kr. Giri, Ankurkumar J. Khimani, Yati H. Vaidya, Parth Thakor, Anjali B. Thakkar, and Milind P. Deshpande
American Chemical Society (ACS)
The strategy of chemical coprecipitation is implemented to synthesize nanoparticles of pristine CuSe, 5 and 10% Ni-doped CuSe, and 5 and 10% Zn-doped CuSe. All of the nanoparticles are found to be near stoichiometric by the evaluation of X-ray energy using electron dispersion spectra, and the elemental mapping shows uniform distribution. By X-ray diffraction examination, all of the nanoparticles are identified as being single-phase and having a hexagonal lattice structure. Field emission microscopy with electrons in both scanning and transmission modes affirmed the spherical configuration of the nanoparticles. The crystalline nature of the nanoparticles is confirmed by the presence of spot patterns observed in the selected area electron diffraction patterns. The observed d value matches well with the d value of the CuSe hexagonal (102) plane. Findings from dynamic light scattering reveal the size distribution of nanoparticles. The nanoparticle's stability is investigated by ζ potential measurements. Pristine and Ni-doped CuSe nanoparticles exhibit ζ potential values in the preliminary stability band of ±10 to ±30 mV, while Zn-doped nanoparticles feature moderate stability levels of ±30 to ±40 mV. The potent antimicrobial effects of synthesized nanoparticles are studied against Staphylococcus aureus, Pseudomonas aeruginosa, Proteus vulgaris, Enterobacter aerogenes, and Escherichia coli bacteria. The 2,2-diphenyl-1-picrylhydrazyl scavenging test is used to investigate the nanoparticle's antioxidant activities. The results showed the highest activity for control (Vitamin C) with an IC50 value of 43.6 μg/mL, while the lowest for Ni-doped CuSe nanoparticles with an IC50 value of 106.2 μg/mL. Brine shrimps are utilized for in vivo cytotoxicity evaluation of the synthesized nanoparticles, which demonstrates that 10% Ni- and 10% Zn-doped CuSe nanoparticles are more damaging on brine shrimp instead on other nanoparticles with a 100% mortality rate. The lung cancer cell line of human (A549) is used to investigate in vitro cytotoxicity. The results indicate that pristine CuSe nanoparticles are more effective in the context of cytotoxicity against the A549 cell lines, possessing an IC50 of 488 μg/mL. The particulars of the outcomes are explained in depth.
Rohitkumar M. Kannaujiya, Sunil H. Chaki, Ankurkumar J. Khimani, Ranjan Kr. Giri, Anilkumar B. Hirpara, Yati H. Vaidya, and Milind P. Deshpande
Elsevier BV
Priteshkumar M. Thakor
Rasayan Journal of Chemistry
Organic research has recently focused on the development of a more environmentally friendly process that uses alternate reaction media in place of harmful and expensive catalysts. So here a facile protocol was developed for the green synthesis of a novel Schiff base ligand, and the synthesized ligand was characterized using physicochemical techniques. The homobinuclear complexes of synthesized ligands made of Iron (II), Cobalt (II), Manganese (II), Nickel (II), Zinc (II), and Copper (II) were characterized through the FTIR technique after synthesizing them conventionally. The in-vitro antimicrobial and antioxidant activities were examined for all the synthesized compounds
Divyeshkumar Dave, Kamlesh Chauhan, Ankurkumar Khimani, Krina Soni, and Yati Vaidya
Informa UK Limited
ABSTRACT The biodegradation of low-density Polyethylene (LDPE) is usually time-consuming, In the presence of Titania-nanoparticles, LDPE is photocatalytically degraded in smaller fragments afterward the bacteria can effectively degrade polyethylene. In the current study, potent polyethylene degrading bacteria were screened from the soil of the local dumpsite and identified using 16s rRNA sequencing. The protein-coated titania nanoparticle (TNPs) was synthesized using Sol-gel Method and characterized by XRD, and SAED-HRTEM. The photocatalytic biodegradation of LDPE (30 microns) in presence of 1M NaOH was studied by exposing it to UV irradiation, visible light, and high temperature (50°C) for 21 days separately and photocatalytic biodegradation was assessed by monitoring % weight loss at every 7 days’ time interval, tensile strength, and FTIR. After 21 days of photocatalytic biodegradation, LDPE film containing both TNPs and Lactobacillus plantarum along with 1M NaOH in presence of visible light was unveiled oxidation and enumerated via the occurrence of strong absorptions band of the carbonyl group (C=O) and also the breaking and weakening of existing absorptions bonds along with the new carbonyl functional group formation. The decline in tensile strength was measured at 21% after 21 days. Thus, experimental results on LDPE after exposure to visible irradiation along with Lactobacillus plantarum and 5% protein-coated TNP showed improvement in degradation rate and elongation 59 % and 51% within 21 days, respectively in comparison to another study (49 % Weight loss and 12% elongation after 45 days). An excellent application of this research is significantly reduced plastic waste via a maintained procedure. GRAPHICAL ABSTRACT
Anilkumar B. Hirpara, Sunil H. Chaki, Rohitkumar M. Kannaujiya, Ankurkumar J. Khimani, Zubin R. Parekh, Yati H. Vaidya, Ranjan Kr. Giri, and M.P. Deshpande
Elsevier BV
Ranjan Kr. Giri, Sunil Chaki, Ankurkumar J. Khimani, Yati H. Vaidya, Parth Thakor, Anjali B. Thakkar, Swati J. Pandya, and Milind P. Deshpande
American Chemical Society (ACS)
A simple hydrothermal route is employed to synthesize pure copper indium disulfide (CIS) and CIS nanoparticles (NPs) mediated by various natural plant extracts. The plant extracts used to mediate are Azadirachta indica (neem), Ocimum sanctum (basil), Cocos nucifera (coconut), Aloe vera (aloe), and Curcuma longa (turmeric). The tetragonal unit cell structure of as-synthesized NPs is confirmed by X-ray diffraction. The analysis by energy-dispersive X-rays shows that all the samples are near-stoichiometric. The morphologies of the NPs are confirmed by high-resolution scanning and transmission modes of electron microscopy. The thermal stability of the synthesized NPs is determined by thermogravimetric analysis. The optical energy band gap is determined from the absorption spectra using Tauc’s equation. The antimicrobial activity analysis and the estimation of the minimum inhibitory concentration (MIC) value of the samples are performed for Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris, Enterobacter aerogenes, and Staphylococcus aureus pathogens. It shows that the aloe-mediated CIS NPs possess a broad inhibitory spectrum. The best inhibitory effect is observed against S. aureus, whereas the least effect was exhibited against P. vulgaris. The least MIC value is found for aloe-mediated CIS NPs (0.300 mg/mL) against S. aureus, P. aeruginosa, and E. aerogenes, along with basil-mediated NPs against E. coli. The antioxidant activity study showed that the IC50 value to inhibit the scavenging activity is maximum for the control (vitamin C) and minimum for pure CIS NPs. The in vivo cytotoxicity study using brine shrimp eggs shows that the pure CIS NPs are more lethal to brine shrimp than the natural extract-mediated CIS NPs. The in vitro cytotoxicity study using the human lung carcinoma cell line (A549) shows that the IC50 value of turmeric extract-mediated CIS NPs is minimum (15.62 ± 1.58 μg/mL). This observation reveals that turmeric extract-mediated CIS NPs are the most potent in terms of cytotoxicity toward the A549 cell line.
Shriram H. Patel, Yati H. Vaidya, Reena J. Patel, Ramesh J. Pandit, Chaitanya G. Joshi, and Anju P. Kunjadiya
Springer Science and Business Media LLC
AbstractBreastfeeding undoubtedly provides important benefits to the mother-infant dyad and should be encouraged. Mastitis, one of the common but major cause of premature weaning among lactating women, is an inflammation of connective tissue within the mammary gland. This study reports the influence of mastitis on human milk microbiota by utilizing 16 S rRNA gene sequencing approach. We sampled and sequenced microbiome from 50 human milk samples, including 16 subacute mastitis (SAM), 16 acute mastitis (AM) and 18 healthy-controls. Compared to controls, SAM and AM microbiota were quite distinct and drastically reduced. Genera including, Aeromonas, Staphylococcus, Ralstonia, Klebsiella, Serratia, Enterococcus and Pseudomonas were significantly enriched in SAM and AM samples, while Acinetobacter, Ruminococcus, Clostridium, Faecalibacterium and Eubacterium were consistently depleted. Further analysis of our samples revealed positive aerotolerant odds ratio, indicating dramatic depletion of obligate anaerobes and enrichment of aerotolerant bacteria during the course of mastitis. In addition, predicted functional metagenomics identified several gene pathways related to bacterial proliferation and colonization (e.g. two-component system, bacterial secretion system and motility proteins) in SAM and AM samples. In conclusion, our study confirmed previous hypothesis that mastitis women have lower microbial diversity, increased abundance of opportunistic pathogens and depletion of commensal obligate anaerobes.
Yati H. Vaidya, Shriram H. Patel, Reena J. Patel, Ramesh J. Pandit, Chaitanya G. Joshi, and Anju P. Kunjadia
Elsevier BV
Shriram H. Patel, Yati H. Vaidya, Chaitanya G. Joshi, and Anju P. Kunjadia
Springer Science and Business Media LLC