Prof. Modinah Adenike Oladayo ABDUL RAHEEM

@unilorin.edu.ng

Professor, Faculty of Physical Sciences
Head, Others
University of Ilorin, Ilorin, Nigeria

Prof. Modinah Adenike Oladayo ABDUL RAHEEM


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https://researchid.co/ademode

RESEARCH, TEACHING, or OTHER INTERESTS

Physical and Theoretical Chemistry, Atmospheric Science, Environmental Chemistry, Pollution
4

Scopus Publications

202

Scholar Citations

8

Scholar h-index

5

Scholar i10-index

Scopus Publications

  • Elucidating Phytochemicals and Folklore Constituents for Multitargeted Disease Mitigation
    Modinah Adenike Oladayo Abdul Raheem, Ibrahim Adekunle Oreagba, Fausat Kikelomo Ola-Mudathir, Halimat Amin Abdulrahim, Mariam Dasola Adeoye
    Pharmacology Characterizations Toxicity and Herb Drug Interactions of Herbs in Traditional Medicine, 2026
    This chapter delves into the fascinating intersection of folk medicine and modern pharmacology, focusing on plant-based remedies used in traditional healing practices for tackling multiple diseases. It highlights the importance of ecochemical interface studies, exploring how factors like climate, soil, and pollution affect the effectiveness of medicinal plants. By combining traditional knowledge with contemporary scientific approaches, the chapter uncovers the full potential of plant compounds for multitarget disease treatments. Topics covered include phytochemical profiling, pharmacodynamics, and how environmental stress impacts plant chemistry. Through real-life case studies, we see how specific plants have proven therapeutic effects, underscoring the value of cross-disciplinary collaboration and ethical sourcing. The chapter concludes by calling for future research that bridges eco-centric drug discovery with personalized medicine, leveraging innovative tools such as AI and systems biology to fully realize the therapeutic promise of natural compounds.
  • Assessment of Kitchen Air Pollution: Health Implications for the Residents of Ilorin South, Nigeria
    Modinah Abdul Raheem, Ganiyat Jimoh, Halimat Abdulrahim
    Journal of Environmental and Public Health, 2022
    Indoor air quality is essential, so its quality cannot be compromised. Hence, this research assessed indoor gaseous air pollutant concentrations from sources in thirty-three residential kitchens within the 4-zone of Ilorin-South Local Government, Kwara, Nigeria. The work focused on SO2, NO2, and CO emission concentration quantification, determination of the air quality index (AQI), estimation of health assessment risk, and deduced their health implications on the residents. The concentrations of NO2 and SO2 were determined by the Saltzman method using a Gilair-3 air sampler, while the concentration of CO was determined using an MSA Altair-5x multigas detector. Three types of eleven kitchen environments each (kitchens where liquefied petroleum gas (LPG), charcoal, and firewood were used as fuel sources) were considered. The concentrations of NO2, SO2, and CO were higher in kitchens that used charcoal and firewood. The major health risks were deduced in percentages from the questionnaire administered, where headaches had the highest percentage (20.7). The model indicated that the concentrations of the pollutants in the evening, irrespective of the sampling points, were higher than those in the morning. Firewood contributed significantly more than charcoal and LPG ( p < 0.05 ). The results of the health assessment risk showed that the risk estimated for normal exposure to the pollutants in all the households studied revealed a hazard quotient of <1.0 except for SO2 from firewood for infants and children = 1.09. The AQI results showed the worst health conditions for households that used firewood (0.103–4.760 ppm NO2; 0.327–0.647 ppm SO2; and 12.30–57.83 ppm CO). The study concluded that the use of LPG should be preferred as a source of fuel for cooking.
  • Explicit Solvent Molecular Dynamics Simulation Studies of the Dissociation of Human Insulin Hexamer into the Dimeric Units
    O. K. Yusuff, Abdulrafiu Tunde Raji, M. A. Raheem, D. B. Ojo
    Advanced Journal of Chemistry Section A, 2020
    The molecular dynamics (MD) simulation of two structures of human insulin hexamers (Zn-hexamer and Znfree-hexamer) in explicit solvent was performed and the role of the Zn2+ ions in the hexamer’s cavity as it may affect the propensities of the dissociation of insulin hexamer into dimers and monomers investigated. The starting structure of the Zn-hexamer contains two cavity water molecules and two Zn2+ ions in addition to the amino acids residues of the insulin hexamer while the starting structure Znfree-hexamer is made up of only the amino acids residues of the insulin hexamer. The MD simulation was performed for 1 µs under the isothermal-isobaric conditions (NPT) conditions using the GROMACS software, amber ff99-SB force field, TIP 3P water model with periodic boundary conditions imposed on x-, y- and z- directions. Structural analyses of the two experimental structures were carried out and root mean square deviations (RMSD) and root mean square fluctuations (RMSF) computed from the referenced initial structures. The average RMSD value of the backbone atoms for the Zn-hexamer is 0.293 nm and Znfree-hexamer is 0.785 nm. The structural analysis revealed that, there were dimer’s dissociation and pronounced fluctuations of the amino acids residues in the Znfree-hexamer compared to the Zn-hexamer during the MD simulation. This is evident in the higher inter-dimer distances of the six glutamate-13(β) residues in the Znfree-hexamer which confirmed the influence of the removal of the Zn2+ ions and cavity water molecules on dissociation of the insulin hexamer.
  • Kinetics and Mechanism of the Antioxidant Activities of C. olitorius and V. amygdalina by Spectrophotometric and DFT Methods
    Olaniyi K. Yusuff, Modinah Adenike O. Abdul Raheem, Abdulrahman A. Mukadam, Ridwan Oladayo Sulaimon
    ACS Omega, 2019
    The kinetics and mechanism of the antioxidant activities of the methanolic extract of the leaves of two vegetables [Corchorus olitorius (C. olitorius) and Vernonia amygdalina (V. amygdalina)] have been studied using experimental and theoretical approaches. The kinetics (second order and pseudo-first order) of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activities of the leaf extracts at varying times (30–90 min) were determined using the UV–visible spectrophotometry method at λmax = 517 nm, whereas the mechanism was studied by density functional theory at two levels of functionals (B3LYP and LC-ωPBE) using bond dissociation enthalpy and adiabatic ionization potential values. Molecular properties such as the highest occupied molecular orbital, lowest unoccupied molecular orbital, electronegativity (χ), electrophilicity (ω), hardness (η), and softness (S) of the predominant phenolic antioxidants were also compared. The second-order kinetics is favored by both plants rather than pseudo-first order; however, V. amygdalina with a second-order rate constant k2 of 0.0152 (mM)−1 min–1 is faster in scavenging DPPH radicals than C. olitorius with a k2 value of 0.0093 (mM)−1min–1. Chlorogenic acid and luteolin-7-O-β-glucuronide, which are the most abundant phenolic acid antioxidant in C. olitorius and V. amygdalina, both preferably scavenge the DPPH radical via a hydrogen atom transfer mechanism. This is evident from their lower bond dissociation enthalpy values than the adiabatic ionization potential values. Successful molecular docking of these phenolic compounds indicates that both compounds form favorable interactions with the therapeutic target, xanthine oxidase.

RECENT SCHOLAR PUBLICATIONS

  • Elucidating Phytochemicals and Folklore Constituents for Multitargeted Disease Mitigation
    MAOA Raheem, IA Oreagba, FK Ola-Mudathir, HA Abdulrahim, ...
    Pharmacology, Characterizations, Toxicity, and Herb-Drug Interactions of … , 2026
    2026
  • Strengthening the Traditional Conflict Resolution Mechanisms on Marital Conflict in Ilorin Emirate of Kwara State
    S Idowu, R SA, M Raheem
    Published by Society for Peace Studies and Practice, Institute of Peace and … , 2024
    2024
  • Assessment of Kitchen Air Pollution: Health Implications for the Residents of Ilorin South, Nigeria
    MA Raheem, G Jimoh, H Abdulrahim
    Journal of Environmental and Public Health 2022, 13 , 2022
    2022
    Citations: 20
  • Kinetics of the antioxidant activities of Solanum macrocapon and Crassocephalum rubens by DPPH radical scavenging method
    OK YUSUFF, K Omotosho, K Mustapha, AMO Abdulraheem
    Journal of Chemical Society of Nigeria 45 (1) , 2020
    2020
    Citations: 2
  • Explicit solvent molecular dynamics simulation studies of the dissociation of human insulin hexamer into the dimeric units
    OK Yusuff, A Tunde Raji, MAO Abdul Raheem, D Boluwaji Ojo
    Adv. J. Chem. A 3, 730-739 , 2020
    2020
    Citations: 6
  • Assessment of the polluting effects of the iponri-alaka canal, Lagos state, Nigeria
    AMO Abdul Raheem, EU Adah
    International Journal of Environmental Analytical Chemistry 99 (13), 1340-1352 , 2019
    2019
    Citations: 1
  • Kinetics and Mechanism of the Antioxidant Activities of C. olitorius and V. amygdalina by Spectrophotometric and DFT Methods
    OK Yusuff, MAO Abdul Raheem, AA Mukadam, RO Sulaimon
    ACS omega 4 (9), 13671-13680 , 2019
    2019
    Citations: 34
  • Kinetics investigation and Equilibrium studies on the biosorption Leuco-form of Indigo Blue dye using chemically modified Coconut fibre
    OK Yusuff, AMOA Raheem, OD Agboola
    Ilorin Journal of Science 6 (1), 67-78 , 2019
    2019
  • Environmental Monitoring of NOX, Total Oxidants and the Implications for Photochemistry of Air Pollution over Ilorin Shed, Nigeria
    AR AMO, FA Adekola, IB Obioh
    Journal of Chemistry 7 (1), 1-14 , 2019
    2019
    Citations: 1
  • An Assessment of vehicular emissions and related health impacts along Ilorin-Lagos highway in Nigeria
    MAOA Raheem, KO Ajayi, OA Awoyemi
    Annals of Science and Technology 4 (2), 78-87 , 2019
    2019
    Citations: 9
  • Safety assessment of Chitosan bound to Ethylacetate fraction of cocos nucifera husk fiber methanolic extract in mice
    ANO Sulaiman A. F., Oloyede H.O.B., Akanji M. A., Akolade J. O., Abdul ...
    NISEB Journal 19 (1), 118 - 129 , 2019
    2019
  • Experimental and Theoretical estimations of dipole moments of monocyclic and bicyclic aromatic compounds
    O Abdul Raheem, A. M. O., Mukadam, A. A., Yusuff, O. K., Buhari, S. S., Abubakar
    Bulletin of Science Association of Nigeria. 29, 41 - 53 , 2019
    2019
  • NITRATE, SULPHATE AND HEAVY METALS IN LEAVES OF SELECTED PLANTS IN BOTANICAL GARDENS OF TWO NIGERIAN UNIVERSITIES
    AMOA Raheem, AA Mukadam, OK Yusuff, AA Igbin, CF Udogu
    Journal of Chemical Society of Nigeria 43 (2) , 2018
    2018
  • Synthesis and characterization of new unsymmetrical bis-Schiff bases
    DYAACT Samson O. Owalude, Modinah A.O. Abdul Raheem
    Nig. J. Pure & Appl. Sci. 31 (2), 3228 -3234 , 2018
    2018
  • Extraction, physicochemical, phytochemical, biochemical, GC-MS constituents and environmental effects of Petiveria alliacea leaves
    AMOA Raheem, FA Sulaiman, OL Malomo, MM Oyewo, A Hassan, ...
    CPJ 2018022, 24210 , 2018
    2018
    Citations: 3
  • The Kinetics and Thermodynamics studies of the biosorption of Chromium (III) ions from aqueous solution using groundnut husk
    AA Olaniyi K Yusuff, AbdulRahman A. Mukadam, Adenike M.O Abdulraheem
    Journal of Research and Review in Science 5, 92-99 , 2018
    2018
    Citations: 4
  • Assessment of Environmental Factors on Secondary Metabolites and Toxicological Effects of Datura metel Leaves Extracts
    TO Modinah A.O. Abdul Raheem 1*, Faoziyat A. Sulaiman 2, Halimat A ...
    Annals of Science and Technology - A 3 (2), 8-19 , 2018
    2018
    Citations: 3
  • Environmental Impact Assessment of Daytime Atmospheric Sulphur Dioxide in Lagos, Nigeria
    AMO Abdul Raheem, FA Adekola, IB Obioh
    Journal of Chemical Society of Nigeria 42 (2), 71 - 75 , 2017
    2017
  • ENVIRONMENTAL IMPACT ASSESSMENT OF DAYTIME ATMOSPHERIC SULPHUR DIOXIDE IN LAGOS NIGERIA
    FAAIBO A.M.O. Abdul Raheem1*
    J. Chem. Soc. Nigeria 42 (2), 71-75 , 2017
    2017
  • Evaluation of some heavy metals loading in dust fall of three universities motor parks in Western Nigeria
    FO Nwosu, MOA Raheem, Z Shehu
    Journal of Applied Science & Environmental Management 20 (2), 327 , 2016
    2016
    Citations: 9

MOST CITED SCHOLAR PUBLICATIONS

  • Kinetics and Mechanism of the Antioxidant Activities of C. olitorius and V. amygdalina by Spectrophotometric and DFT Methods
    OK Yusuff, MAO Abdul Raheem, AA Mukadam, RO Sulaimon
    ACS omega 4 (9), 13671-13680 , 2019
    2019
    Citations: 34
  • The seasonal variation of the concentrations of ozone, sulfur dioxide, and nitrogen oxides in two Nigerian cities
    AMO Abdul Raheem, FA Adekola, IO Obioh
    Environmental Modeling & Assessment 14 (4), 497-509 , 2009
    2009
    Citations: 34
  • Heavy metals distribution and speciation in soils around a mega cement factory in north-central Nigeria
    FA Adekola, AA Inyinbor, AMOA Raheem
    Ethiopian Journal of Environmental Studies and Management 5 (1), 11-19 , 2012
    2012
    Citations: 22
  • Assessment of Kitchen Air Pollution: Health Implications for the Residents of Ilorin South, Nigeria
    MA Raheem, G Jimoh, H Abdulrahim
    Journal of Environmental and Public Health 2022, 13 , 2022
    2022
    Citations: 20
  • Monitoring of sulfur dioxide in the guinea savanna zone of Nigeria: implications of the atmospheric photochemistry
    AMOA Raheem, FA Adekola, IB Obioh
    Bulletin of the Chemical Society of Ethiopia 23 (3), 383-390 , 2009
    2009
    Citations: 15
  • An Assessment of vehicular emissions and related health impacts along Ilorin-Lagos highway in Nigeria
    MAOA Raheem, KO Ajayi, OA Awoyemi
    Annals of Science and Technology 4 (2), 78-87 , 2019
    2019
    Citations: 9
  • Evaluation of some heavy metals loading in dust fall of three universities motor parks in Western Nigeria
    FO Nwosu, MOA Raheem, Z Shehu
    Journal of Applied Science & Environmental Management 20 (2), 327 , 2016
    2016
    Citations: 9
  • Determination of sulphur (IV) oxide in Ilorin city, Nigeria, during dry season
    AR Amo, FA Adekola, IB Obioh
    Journal of Applied Sciences and Environmental Management 10 (2) , 2006
    2006
    Citations: 8
  • Explicit solvent molecular dynamics simulation studies of the dissociation of human insulin hexamer into the dimeric units
    OK Yusuff, A Tunde Raji, MAO Abdul Raheem, D Boluwaji Ojo
    Adv. J. Chem. A 3, 730-739 , 2020
    2020
    Citations: 6
  • Comparative Studies of Water and Sediment Qualities of Some Dams in Kwara State
    AMO *Abdus-Salam, N., Awoyemi, B. O. and Abdul Raheem
    Fountain Journal of Natural and Applied Sciences 5 (1), 38-52 , 2016
    2016
    Citations: 6
  • Variation of source distribution of total oxidants: Contributions of oxides of nitrogen, sulphur (IV) oxide emissions and background ozone from Lagos-Nigeria
    AMOA Raheem, FA Adekola
    International Journal 8 (11), 411-420 , 2013
    2013
    Citations: 5
  • Microscopic Parameters in the Excited State of Toluene and Some of Its Haloderavatives
    AMO Abdul Raheem
    Journal of Sciences, Islamic Republic of Iran 21 (1) , 2010
    2010
    Citations: 5
  • Levels of Cadmium, Lead and Zinc introduced as contaminants into foodstuffs during processing
    IA Bello, O Oke, AO Abdul Raheem, A. M. O. and Ibrahim
    SCIENCE FOCUS 12 (2), 1 - 5 , 2007
    2007
    Citations: 5
  • The Kinetics and Thermodynamics studies of the biosorption of Chromium (III) ions from aqueous solution using groundnut husk
    AA Olaniyi K Yusuff, AbdulRahman A. Mukadam, Adenike M.O Abdulraheem
    Journal of Research and Review in Science 5, 92-99 , 2018
    2018
    Citations: 4
  • Extraction, physicochemical, phytochemical, biochemical, GC-MS constituents and environmental effects of Petiveria alliacea leaves
    AMOA Raheem, FA Sulaiman, OL Malomo, MM Oyewo, A Hassan, ...
    CPJ 2018022, 24210 , 2018
    2018
    Citations: 3
  • Assessment of Environmental Factors on Secondary Metabolites and Toxicological Effects of Datura metel Leaves Extracts
    TO Modinah A.O. Abdul Raheem 1*, Faoziyat A. Sulaiman 2, Halimat A ...
    Annals of Science and Technology - A 3 (2), 8-19 , 2018
    2018
    Citations: 3
  • Heavy metal pollution study of Onyi river in Obajana Community of Kogi State, Nigeria
    AA Inyinbor, FA Adekola, AM Abdul Raheem
    J Appl Chem 2 (3), 26-31 , 2012
    2012
    Citations: 3
  • Kinetics of the antioxidant activities of Solanum macrocapon and Crassocephalum rubens by DPPH radical scavenging method
    OK YUSUFF, K Omotosho, K Mustapha, AMO Abdulraheem
    Journal of Chemical Society of Nigeria 45 (1) , 2020
    2020
    Citations: 2
  • Air Pollution: A Case Study of Ilorin and Lagos Outdoor Air
    AMOA Raheem, FA Adekola
    Indoor and Outdoor Air Pollution , 2011
    2011
    Citations: 2
  • Modification and Validation of a Sampling Method for Ozone, Sulphur (IV) Oxide and Oxides of Nitrogen in the Ambient Air
    AMO Abdul Raheem, IB Adekola, F. A. and Obioh
    Science Focus 14 (2), 166 - 185 , 2009
    2009
    Citations: 2