Benjamin Olusomi Bolaji

@unilorin.edu.ng

Professor, Faculty of Clinical Sciences
Professor, Faculty of Clinical Sciences
University of Ilorin, Ilorin, Nigeria

Benjamin Olusomi Bolaji


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https://researchid.co/boolusomi
Prof. Bolaji is a graduate of the University of Ibadan, Ibadan, MBBS 1983. He had his internship at the Ahmadu Bello University Teaching Hospital, Kaduna 1983/84 He joined the residency training in anaesthesia at the University of Ilorin Teaching Hospital (UITH) in 1990, had his residency training at the University of Calabar Teaching Hospital, Calabar (1990/91) and the University College Hospital, Ibadan (1992-1997), obtain the DA (1991) and the FMCA (1998). He joined the services of the University of Ilorin in 1998 as a Las a Lecturer I in the Department of Anaesthesia. He was promoted Professor of Anaesthesia in 2017. his research interests are: Critical care and airway management.

EDUCATION

University of Ibadan, Ibadan, Nigeria. 1977-1983. MBBS (1983)
University of Calabar, Calabar, Nigeria. 1990-1992. Diploma in Anaesthesiology (DA, 1992)
National Postgraduate Medical College of Nigeria. 1992-1998. Fellow of the Medical College in Anaesthesia (FMCA, 1998)

RESEARCH, TEACHING, or OTHER INTERESTS

Anesthesiology and Pain Medicine, Critical Care and Intensive Care Medicine
31

Scopus Publications

Scopus Publications

  • The African Critical Illness Outcomes Study (ACIOS): a point prevalence study of critical illness in 22 nations in Africa
    Tim Baker, Juan Scribante, Muhammed Elhadi, Adesoji Ademuyiwa, Babatunde Osinaike, et al.
    Lancet, 2025
  • Effectiveness of topical bupivacaine versus topical lidocaine/adrenaline mixture for post-adenotonsillectomy pain management
    O. Oyedepo, O. Ige, Emmanuel Ikechukwu Oparanozie, Benjamin Olusomi Bolaji, S. O. Idris, et al.
    Egyptian Journal of Otolaryngology, 2024
  • Comparative effects of intravenous esmolol and lidocaine on bispectral index during propofol-fentanyl induction in patients scheduled for elective surgeries under general anaesthesia
    O. O Oladosu, B. O. Bolaji, O. A. Ige, I. I. Enaworu, A. Alawode
    Rwanda Medical Journal, 2023
    INTRODUCTION: Laryngoscopy and endotracheal intubation at induction of anaesthesia have been associated with awareness and haemodynamic fluctuations. Agents that can mitigate these effects should create better anaesthetic conditions. This study aimed to compare the effects of intravenous esmolol and lidocaine on the bispectral index (BIS) and haemodynamic responses during induction of general anaesthesia with propofol/fentanyl in adult patients scheduled for elective surgical procedures.
 METHODS: This was a prospective randomized controlled study in ninety patients aged 18-65 years who were randomized into three groups to receive either IV esmolol 0.5 mg/kg, IV lidocaine 1.5 mg/kg or normal saline prior to induction of general anaesthesia.
 RESULTS: The esmolol group had a significantly shorter induction time (p<0.0001) and a lower dose of propofol consumed (p<0.0001) than the lidocaine group. The mean pulse rate was significantly lower at the 1st min to 4th min post-intubation in esmolol and lidocaine groups compared to the control group (p values; 1 min= 0.005, 2 min= 0.008, 3 min= 0.023, 4 min= 0.018). There was a significant difference in the systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) in the three groups at 2 min post-intubation.
 CONCLUSION: Pre-induction intravenous esmolol 0.5 mg/kg was more effective than intravenous lidocaine 1.5 mg/kg in reducing the induction dose of propofol and the induction time. Esmolol also prevented increases in BIS better than lidocaine following endotracheal intubation but both agents were equally effective in attenuating the haemodynamic changes associated with laryngoscopy and endotracheal intubation.
  • Effect of spinal anesthesia on QT interval: Comparative study of severe pre-eclamptic and normotensive parturients undergoing cesarean section
    AM Adedapo, BO Bolaji, MB Adegboye, PM Kolo, JA Ogunmodede, et al.
    Nigerian Journal of Clinical Practice, 2022
    Aim: This study aimed to compare the effect of spinal anesthesia on QT interval in severe pre-eclamptic and normotensive parturients who underwent cesarean section in a Nigerian tertiary hospital. Patients and Methods: Twelve-lead electrocardiogram (ECG) was obtained before, and at intervals after spinal anaesthesia on fifty severe pre-eclamptic (Group A) and fifty normotensive parturients (Group B) who underwent caesarean section. The effect of spinal anaesthesia on QT interval was compared. Results: The preoperative (baseline) mean QT interval was longer in group A than in group B; 453.10 ± 34.11 ms versus 399 ± 18.79 ms, P < 0.001. The prevalence of prolonged QT interval in the severe pre-eclamptic group before spinal anesthesia was 80% while in the normotensive group it was 0%, P < 0.001. At 5, 30, 60, and 120 min after the establishment of spinal anesthesia, the mean QT interval in the severe pre-eclamptic group was shortened and maintained within normal limits; 414.74 ± 28.05, 418.28 ± 30.95, 411.18 ± 19.21 and 401.36 ± 17.52 ms with P < 0.001 throughout. In the normotensive group, there was no significant change in the mean QT interval. Conclusions: This study demonstrated that the QT interval was more prolonged among the severe pre-eclamptic parturients. Spinal anesthesia using 0.5% hyperbaric bupivacaine normalized the QT interval and maintained it within normal limits during the study period.
  • Comparative Study of Haemodynamic Effects of Intravenous Ketamine-fentanyl and Propofol-fentanyl for Laryngeal Mask Airway Insertions in Children Undergoing Herniotomy under General Anaesthesia in a Nigerian Tertiary Hospital
    Ajibade Okeyemi, AliyuZakari Suleiman, OlubukolaOlanrewaju Oyedepo, BenjamiOlusomi Bolaji, BabajideMajeed Adegboye, et al.
    Nigerian Postgraduate Medical Journal, 2022
    Background: Insertion of laryngeal mask airway (LMA) with propofol in children may cause hypotension, laryngospasm and apnoea. Ketamine and fentanyl have been combined separately with propofol to prevent depression of cardiovascular system during LMA insertion, especially in paediatric patients. Ketamine-fentanyl and propofol-fentanyl combinations have analgesic effect, prevent coughing and apnoea and regarded as agents of choice for LMA insertions. However, the cardiovascular effects of the two admixtures for LMA insertions have not been fully assessed in children. We compared the haemodynamic effects of ketamine-fentanyl and propofol-fentanyl combinations for LMA insertion in paediatric patients who underwent herniotomy in our facility. Patients and Methods: This comparative study was conducted on 80 children aged 1–15 years, ASA physical Statuses I and II, who had herniotomy under general anaesthesia. The patients were randomised into two groups (A and B) of 40 patients each and LMA was inserted following administrations of the two different drug combinations. Patients in Group A received pre-mixed ketamine 2 mg/kg and fentanyl 2 μg/kg while the patients in Group B received pre-mixed propofol 2.5 mg/kg and fentanyl 2 μg/kg. The blood pressure and incidence of apnoea were determined in the two groups during and after the LMA insertion. Results: The haemodynamic states of the patients were not comparable statistically as the heart rate, systolic, diastolic and mean arterial blood pressure were significantly higher and stable in the ketamine-fentanyl group than the propofol-fentanyl group (P < 0.05). The incidence of apnoea was significantly lower in the ketamine-fentanyl group compared with propofol-fentanyl group (P = 0.045), but post-anaesthesia discharge scores were similar, with no significant difference in both groups (P = 0.241). Conclusion: The use of ketamine-fentanyl combination for LMA insertion in paediatric patients was associated with better haemodynamic changes and lower incidence of apnoea when compared with propofol-fentanyl combination.
  • Modified electroconvulsive therapy in a resource-challenged setting: Comparison of two doses (0.5 mg/kg and 1 mg/kg) of suxamethonium chloride
    OlurotimiI Aaron, AramideF Faponle, BenjaminO Bolaji, SamuelK Mosaku, AnthonyT Adenekan, et al.
    Saudi Journal of Anaesthesia, 2020
    Background: Suxamethonium has been shown to have a superior modification of the convulsion associated with ECT compared to other muscle relaxants. The dosage of suxamethonium used in ECT varies widely based on the experiences of practitioners. The study aimed to determine and compare the effectiveness and side effect profile of 0.5 mg/kg and 1 mg/kg in modified ECT. Subjects and Methods: This was a prospective randomized crossover study, comparing the effects of suxamethonium at a dose of 0.5 mg/kg, and 1.0 mg/kg in 27 patients who had a total of 54 sessions of modified ECT. The primary outcome parameters were quality of convulsion and onset and duration of apnoea. The secondary outcome parameters were hemodynamic variables, arterial oxygen saturation, delayed recovery, muscle pain, vomiting, headache, prolonged convulsion, and serum potassium. Data collected were entered into proforma and analyzed using Statistical Package for Social Sciences (SPSS) version 17.0. Parametric variables are presented as means and standard deviations while non-parametric variables are presented as frequencies and percentages. The level of significance (P-value) was considered at 0.05. Results: Sixteen patients (59%) had acceptable convulsion modification with 0.5 mg/kg suxamethonium compared to 23 patients (85%) with the use of 1.0 mg/kg suxamethonium (P = 0.016). There was no statistically significant difference in the duration of convulsion, the onset of apnoea, and the duration of apnoea with the two doses. Changes in heart rate, blood pressure, arterial oxygen saturation, and serum potassium level that accompany the mECT were comparable with the two doses of suxamethonium studied. Conclusions: A better modification of convulsion with comparable hemodynamic and side effect profile is achieved during mECT with the use of 1.0 mg/kg suxamethonium compared to 0.5 mg/kg.
  • Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans
    COVIDSurg Collaborative
    British Journal of Surgery, 2020
    Background The COVID-19 pandemic has disrupted routine hospital services globally. This study estimated the total number of adult elective operations that would be cancelled worldwide during the 12 weeks of peak disruption due to COVID-19. Methods A global expert response study was conducted to elicit projections for the proportion of elective surgery that would be cancelled or postponed during the 12 weeks of peak disruption. A Bayesian β-regression model was used to estimate 12-week cancellation rates for 190 countries. Elective surgical case-mix data, stratified by specialty and indication (surgery for cancer versus benign disease), were determined. This case mix was applied to country-level surgical volumes. The 12-week cancellation rates were then applied to these figures to calculate the total number of cancelled operations. Results The best estimate was that 28 404 603 operations would be cancelled or postponed during the peak 12 weeks of disruption due to COVID-19 (2 367 050 operations per week). Most would be operations for benign disease (90·2 per cent, 25 638 922 of 28 404 603). The overall 12-week cancellation rate would be 72·3 per cent. Globally, 81·7 per cent of operations for benign conditions (25 638 922 of 31 378 062), 37·7 per cent of cancer operations (2 324 070 of 6 162 311) and 25·4 per cent of elective caesarean sections (441 611 of 1 735 483) would be cancelled or postponed. If countries increased their normal surgical volume by 20 per cent after the pandemic, it would take a median of 45 weeks to clear the backlog of operations resulting from COVID-19 disruption. Conclusion A very large number of operations will be cancelled or postponed owing to disruption caused by COVID-19. Governments should mitigate against this major burden on patients by developing recovery plans and implementing strategies to restore surgical activity safely.
  • Deceased donor organ transplantation potential: A peep into an untapped gold mine
    AdemolaAlabi Popoola, BenjaminOlusomi Bolaji, TimothyOlusegun Olanrewaju, TajudeenOlalekan Ajiboye
    Saudi Journal of Kidney Diseases and Transplantation an Official Publication of the Saudi Center for Organ Transplantation Saudi Arabia, 2020
    Organ transplantation is the gold standard for treating end-stage organ diseases, many of whom are on waiting lists. The reasons for this include the nonavailability of suitable organs to be transplanted. In many nations, most of these challenges have been surmounted by the adoption of deceased donor program, which is not so in sub-Saharan countries such as Nigeria. This study is to audit the potentially transplantable organs available from potential deceased donors from a Nigerian tertiary hospital. This is a study of deaths in the intensive care unit (ICU) and the accident and emergency units of the University of Ilorin Teaching Hospital, Nigeria. Data included the biodata, social history, diagnosis or indications for admission, time of arrival and death, causes of death, associated comorbidities, potential organs available, social history, and availability of relations at the time of death. There were 104 deaths in the ICU and 10 patients in the accident and emergency unit. There were 66 males (57.9%) and 48 females (42.1%). Eighty patients were Muslims (70.2%) and 34 were Christians (19.8%). A total of 33 participants were unmarried (28.9%),whereas 81 (71.1%) were married. The tribes of the patients were Yoruba (105, 92.1%), Igbo (7, 6.1%), Hausa (1, 0.9%), and Nupe (1, 0.9%). The age range was 0.08-85 years. Twenty-two (19.3%) had primary and the remaining had at least secondary education. The causes of death were myriad, and there were relatives available at the times of all deaths. The Maastricht classification of the deaths were Class I - 1 (0.9%), Class II - 37 (32.2%), Class III - 9 (7.8%), Class IV - 20 (17.4%), and Class V - 47(40.9%). There were no transplantable organs in 42 (36.5%), one organ in eight (7%), two organs in two (7%), three organs in one (0.9%), four organs in 13 (11.3%), five organs in six (5.2%), six organs in 11 (9.6%), seven organs in 11 (9.6%), eight organs in five (13%), and nine organs in five (4.3%). Deceased donor sources of organs are worthy of being exploited to improve organ transplantation in Nigeria.
  • Fetus-in-Fetu Airway Teratoma Management of a Newborn in a Low-Resource Country: A Case Report
    Olanrewaju O. Oyedepo, Abdulrasheed A. Nasir, Olufemi A. Ige, Benjamin O. Bolaji, Israel K. Kolawole, et al.
    A A Practice, 2019
    A term baby was delivered by cesarean and found to have an unexpected large teratoma attached to its mouth. Surgical excision was planned within 24 hours. Anesthesia concern of airway control required multidisciplinary team consultation, airway and patient preparation, and anticipation for failure. Challenging airway cases in low-resource countries can be successfully managed with deliberate attention to detail, preparation, and experience.
  • Prospective observational cohort study on grading the severity of postoperative complications in global surgery research
    T E F Abbott, K E Greaves, A Patel, T Ahmad, J Haddow, et al.
    British Journal of Surgery, 2019
    BackgroundThe Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs).MethodsThis was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational cohort study of elective surgery in adults. Data collection occurred over a 7-day period. Severity of complications was graded using Clavien–Dindo and the simpler ISOS grading (mild, moderate or severe, based on guided investigator judgement). Severity grading was compared using the intraclass correlation coefficient (ICC). Data are presented as frequencies and ICC values (with 95 per cent c.i.). The analysis was stratified by income status of the country, comparing HICs with LMICs.ResultsA total of 44 814 patients were recruited from 474 hospitals in 27 countries (19 HICs and 8 LMICs). Some 7508 patients (16·8 per cent) experienced at least one postoperative complication, equivalent to 11 664 complications in total. Using the ISOS classification, 5504 of 11 664 complications (47·2 per cent) were graded as mild, 4244 (36·4 per cent) as moderate and 1916 (16·4 per cent) as severe. Using Clavien–Dindo, 6781 of 11 664 complications (58·1 per cent) were graded as I or II, 1740 (14·9 per cent) as III, 2408 (20·6 per cent) as IV and 735 (6·3 per cent) as V. Agreement between classification systems was poor overall (ICC 0·41, 95 per cent c.i. 0·20 to 0·55), and in LMICs (ICC 0·23, 0·05 to 0·38) and HICs (ICC 0·46, 0·25 to 0·59).ConclusionCaution is recommended when using a treatment approach to grade complications in global surgery studies, as this may introduce bias unintentionally.
  • Expanding renal transplantation organ donor pool in Nigeria
    AdemolaAlabi Popoola, TimothyOlusegun Olanrewaju, BenjaminOlusomi Bolaji, TajudeenOlalekan Ajiboye
    Saudi Journal of Kidney Diseases and Transplantation an Official Publication of the Saudi Center for Organ Transplantation Saudi Arabia, 2018
  • Outcome of intensive care management of acute chest syndrome in a Nigerian teaching hospital: A preliminary report
    East African Medical Journal, 2018
  • Dose related effects of oral clonidine pre-medication on bupivacaine spinal anaesthesia
    MB Adegboye, IK Kolawole, BO Bolaji
    African Health Sciences, 2018
  • The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis
    T.E.F. Abbott, T. Ahmad, M.K. Phull, A.J. Fowler, R. Hewson, et al.
    British Journal of Anaesthesia, 2018
  • Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: A 7-day cohort study of elective surgery
    T. Ahmad, R.A. Bouwman, I. Grigoras, C. Aldecoa, C. Hofer, et al.
    British Journal of Anaesthesia, 2017
  • Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries
    Brennan C. Kahan, Desponia Koulenti, Kostoula Arvaniti, Vanessa Beavis, Douglas Campbell, et al.
    Intensive Care Medicine, 2017
  • Global patient outcomes after elective surgery: Prospective cohort study in 27 low-, middle- and high-income countries
    H. Hemmings, R. Pearse, S. Beattie, P. Clavien, N. Demartines, et al.
    British Journal of Anaesthesia, 2016
  • Predictors of maternal mortality among critically ill obstetric patients
    AS Adeniran, BO Bolaji, AA Fawole, OO Oyedepo
    Malawi Medical Journal, 2015
  • Outcomes of intensive care management of traumatic brain injury in a resource-challenged tertiary health centre
    West African Journal of Medicine, 2014
  • Coagulation profile in severe pre-eclampsia and eclampsia in Ilorin, Nigeria: implications for anaesthetic management in operative obstetrics
    West African Journal of Medicine, 2014
  • Effect of wound infiltration with bupivacaine on pulmonary function after elective lower abdominal operations
    OA Ige, BO Bolaji, IK Kolawole
    African Health Sciences, 2013
  • Comparative study of the haemodynamic effects of propofol and thiopentone in modified electroconvulsive therapy in Nigerians.
    West African Journal of Medicine, 2012
  • Comparative effects of thiopentone and propofol on seizure duration and recovery following modified electroconvulsive therapy in Nigerians
    F.O. Omosofe, B.O. Bolaji, I.K. Kolawole, A.B. Makanjuola
    Research Journal of Medical Sciences, 2012
  • Negative pressure pulmonary oedema following adenoidectomy under general anaesthesia: A case series
    West African Journal of Medicine, 2011
  • Methicillin resistant staphylococcus aureus: Awareness, knowledge and disposition to screening among healthcare workers in critical care units of a Nigerian hospital
    West African Journal of Medicine, 2011
  • Repeat caesarean delivery as a risk factor for abnormal blood loss, blood transfusion and perinatal mortality
    R. Saidu, B. O. Bolaji, A. W. O. Olatinwo, C. M. Mcintosh, A. P. Alio, et al.
    Journal of Obstetrics and Gynaecology, 2011
  • Anaesthesia management for thyroidectomy in a non-euthyroid patient following cardiac failure
    BO Bolaji, GA Rahman, OO Oyedepo
    Nigerian Journal of Clinical Practice, 2011
  • Maternal characteristics as risk factor of abnormal blood loss among women enduring repeat cesarean delivery
    Research Journal of Medical Sciences, 2011
  • Comparison of topical lidocaine [2% gel] and injectable lidocaine [2% solution] for incision and curettage of chalazion in Ilorin, Nigeria.
    Nigerian Postgraduate Medical Journal, 2010
  • Outcome of grommet tube insertions among adult Nigerians with serous otitis media
    BS Alabi, BO Bolaji, S Segun-Busari, SK Aremu, OA Afolabi
    Annals of African Medicine, 2009
  • Subarachnoid block for lower abdominal and lower limb surgery: UITH experience.
    Nigerian Journal of Medicine Journal of the National Association of Resident Doctors of Nigeria, 2002