Ajijolakewu Kamoldeen

Scopus Publications

Energy efficiency in chemo-mechanical pretreatment of oil palm biomass: Sequence analysis and process optimization for enhanced bioethanol production
Yitong Niu, Kamoldeen Abiodun Ajijolakewu, Chee Keong Lee, Cheu Peng Leh
Biomass and Bioenergy, 2026
Restoration of the viability and bioactivity of endophytic fungi using epigenetic modification
R.F. Zakariyah, E.P. Samuel, K.A. Ajijolakewu, A.S. Ayoola, R.N. Ahmed, et al.
Microbe Netherlands, 2026
Bio-Prospecting Locally Relevant Industrial Yeast Strains from Fermented Carbohydrate-Rich Food Waste from Nigeria
Mohammed Salih Al-Janaby, Mohammed Q. Al-Ani, Fadhel M. Lafta
Iraqi Journal of Science, 2025
Breast cancer is a heterogeneous disease with a significant impact of genes involved in apoptosis. Hence, this study aims to assess the contribution of programmed cell death protein 4(PDCD4) miR-21, miR-449b and PDCD4 genes polymorphism in breast cancer pathogenicity. A total of 180 blood samples were collected from Iraqi women aged between 15-80 years, 120 samples were included from breast cancer patients (divided into two groups of 60 patients under treatment and 60 post treatments and recovery) then 60 healthy women as a control group. The extracted genomic DNA was amplified by PCR technique for the loci of interest and PCR products of the tested samples were genotyped using TaqMan real time fluorescent oligonucleotide for SNPs analysis. PDCD4 protein concentration in serum was estimated utilizing ELISA. The results showed significant association (P = 0.016) of miR-449b rs10061133:A>G polymorphism (AA, AG and GG) on the PDCD4 serum levels (3.62 ng/L, 4.75 ng/L and 2.58 ng/L respectively). PDCD4 serum showed to differ significantly (p = 0.001) among the investigated groups: treatment (5.39 ng/L), post-treatment (3.42ng/L), and control (3.19 ng/L). An evaluation of the effects of breast cancer risk factors on the studied parameter revealed that breastfeeding appears to significantly influence PDCD4 serum levels. Women who breastfed exhibited a mean PDCD4 concentration of 4.40 ng/L, compared to 3.25 ng/L for those who did not breastfeed (P=0.026). Additionally, the AUC value (0.7) suggests that PDCD4 protein could be a good predictive marker for treatment response. Overall, the phenotypic expression of PDCD4 demonstrated to be significantly influenced by polymorphisim of PDCD4, miR-21 and miR-449b SNPs, with a considerable impact of breastfeeding in increasing PDCD4 levels that could be utilized to promote breast cancer prevention strategies.
Enhanced Antibacterial Potential of Fractionated Bioactive Compounds Isolated from Endophytic Nigrospora oryzae UILRZ1 in Ocimum gratissimum
Journal of Tropical Biodiversity and Biotechnology, 2025
Worldwide Prevalence of Aflatoxins in Food and Feed
Yusuf Opeyemi Oyebamiji, Kamoldeen Abiodun Ajijolakewu, Ismail Abiola Adebayo
Aflatoxins in Food A Recent Perspective, 2022
Benefits and limitations of phytoremediation: Heavy metal remediation review
Azeez Omoniyi Adeoye, Ismail Abiola Adebayo, Adam Moyosore Afodun, Kamoldeen Abiodun Ajijolakewu
Phytoremediation Biotechnological Strategies for Promoting Invigorating Environs, 2022
Profiling of common bacterial pathogens in fish
Tariq Oluwakunmi Agbabiaka, Ismail Abiola Adebayo, Kamoldeen Abiodun Ajijolakewu, Toyin Olayemi Agbabiaka
Bacterial Fish Diseases, 2022
ISOLATION, CHARACTERIZATION and ANTIBACTERIAL SCREENING of ANTIBIOTICS PRODUCED from STREPTOMYCES ISOLATED from DUMPSITE SOILS in ILORIN, NORTH CENTRAL NIGERIA
Risikat Nike Ahmed, Mercy Oluwaseyi Bamigboye, Kamoldeen Abiodun Ajijolakewu, Sheriffdeen Olakunle Idris, Nimat Toyosi Ajide Bamigboye
Malaysian Journal of Science, 2021
Antibiotics are one of the most exploited metabolites produced by soil actinomycetes. This study isolated fifteen actinomycetes (A1 â€“ A15) from dumpsite soils within Ilorin metropolis & screened them for antibacterial activity. Isolates were identified with morphology & biochemical characteristics.Their activity against clinical bacteria (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae & Staphylococcus aureus) was determined. Their bioactive metabolites after fermentation was assayed for by agar well diffusion & compared with reference antibiotics. Molecular analysis of two most active isolates was done. The most active metabolite was subjected to GCMS. All isolates were identified as Streptomyces, 7 isolates exhibited activity against 3 test bacteria with highest (10.5mmÂ±0.35) by Streptomyces griseoplanus while S. aureus demonstrated total resistance to all isolates. Secondary activity revealed 7 of the metabolites as effective against the bacteria with highest activity (28.5Â±1.04mm) by S. sparsogenes showing similar activity with Cefuroxime (28.01Â±0.01mm). The two most active isolates were Streptomyces griseoplanus strain NR725RL-ISP 5009 & Streptomyces sparsogenes strain NBRC 1308616S & RNA nucleotide similarity revealed close phylogenic relationship. GC-MS revealed10 compounds in S. sparsogenes strain NBRC 1308616S metabolite. Streptomyces from dumpsite soils within Ilorin produced bioactive compounds against clinical test bacteria and thus could be potential sources of antibiotics.
Roles of phytometabolites in the management of obesity
Azeez Omoniyi Adeoye, Ismail Abiola Adebayo, Kamoldeen Abiodun Ajijolakewu
Medicinal and Aromatic Plants Healthcare and Industrial Applications, 2021
Optimization of Conditions for Xylanase Production Using Aspergillus tubingensis Under Different Carbon Sources
Isiaka Kolade, Kamoldeen Ajijolakewu
Fountain Journal of Natural and Applied Sciences, 2021
Xylanases are hydrolytic enzymes with wide range of applications in food processing, bleaching of pulp in paper manufacturing industry, bio-conversion of biomass wastes to fermentable sugars and enhancing nutrient digestibility in animal feeds. The optimization of growth conditions and evaluation of an appropriate substrate as carbon source among cassava peels, corn cobs, wheat bran and rice husk on xylanase production by novel strain of Aspergillus tubingensis under Solid State Fermentation (SSF) was investigated. The fungal isolate was identified based on ribosomal RNA gene and ITS gene sequencing analysis as Aspergillus tubingensis. Results showed that Corn cobs had the highest xylanase production among the four substrates. Corn cobs recorded the highest value of xylanase production at pH of 6.0 (107.97 U/g), after incubation period of 72 hour (111.23 U/g), at temperature of 30oC (44.26 U/g) and at ratio 1:3 (45.68 U/g). The optimum growth conditions for xylanase production by Aspergillus tubingensis were: pH 6.0, incubation period of 72 hours, temperature of 30oC and substrate concentration of 1:3 (4g of substrate per 12ml of fermentation medium). Corn cobs showed the highest yield of xylanase activity (111.23±0.31 U/g), followed by Rice husk (101.91±0.72 U/g), Wheat bran (89.30±1.16 U/g) and Cassava peel (87.03±0.57 U/g). In conclusion, among the various agro residues that were used as carbon sources, Corn cobs had maximum xylanase activity. Various culture conditions were optimized by using one factor at a time method and the maximum xylanase production was obtained at pH of 6.0, incubation period of 72 hour, temperature of 30oC and substrate concentration of 1:3 under solid state fermentation. It is therefore suggested that some other notable environmental and fermentation factors that influence metabolism-mediated production yields of xylanase like aeration, agitation, carbon and nitrogen sources, metal ion requirement, inoculum size etc. should be optimized for maximum production of enzyme. Keywords: Solid State Fermentation, Cassava peels, Corn cobs, Wheat bran, Rice husk
Cellulase Production by Co-culture of Bacillus licheniformis and B. paralicheniformis over Monocultures on Microcrystalline Cellulose and Chicken Manure-supplemented Rice Bran Media
Muinat Olanike Kazeem, Kamoldeen A. Ajijolakewu, Nor’ Aini Abdul Rahman
Bioresources, 2021
Preliminary screening of selected soils in Ilorin, North-central Nigeria for antibiotic-producing actinomycetes
Risikat N. AHMED, Sesan M. SOBA, Mercy O. BAMIGBOYE, Kamoldeen A. AJIJOLAKEWU
Notulae Scientia Biologicae, 2020
Preparation and Fundamental Characterization of Cellulose Nanocrystal from Oil Palm Fronds Biomass
Rudi Dungani, Abdulwahab F. Owolabi, Chaturbhuj K. Saurabh, H. P. S. Abdul Khalil, Paridah M. Tahir, et al.
Journal of Polymers and the Environment, 2017
Characterization of novel Trichoderma hemicellulase and its use to enhance downstream processing of lignocellulosic biomass to simple fermentable sugars
Kamoldeen A. Ajijolakewu, Cheu Peng Leh, Chee Keong Lee, Wan Abdullah Wan Nadiah
Biocatalysis and Agricultural Biotechnology, 2017
Optimization of production conditions for xylanase production by newly isolated strain Aspergillus niger through solid state fermentation of oil palm empty fruit bunches
A. Kamoldeen Ajijolakewu, Cheu Peng Leh, Wan Nadiah Wan Abdullah, Chee keong Lee
Biocatalysis and Agricultural Biotechnology, 2017
Enhanced ethanol production from mild alkali-treated oil-palm empty fruit bunches via co-fermentation of glucose and xylose
Ajijolakewu A. Kamoldeen, Chee Keong Lee, Wan Nadiah Wan Abdullah, Cheu Peng Leh
Renewable Energy, 2017
Assessment of the effect of easily-metabolised carbon supplements on xylanase production by newly isolated Trichoderma asperellum USM SD4 cultivated on oil palm empty fruit bunches
Kamoldeen Abiodun Ajijolakewu, Cheu Peng Leh, Wan Nadiah Wan AbduLLah, Chee Keong Lee
Bioresources, 2016
Soil screening for antibiotic - Producing microrgansms
Advances in Environmental Biology, 2013
Bioleaching of lead from Nigerian anglesite ore by Acidithiobacillus ferrooxidans
Journal of Applied Sciences Research, 2012

RECENT SCHOLAR PUBLICATIONS

Energy efficiency in chemo-mechanical pretreatment of oil palm biomass: Sequence analysis and process optimization for enhanced bioethanol production
Y Niu, KA Ajijolakewu, CK Lee, CP Leh
Biomass and Bioenergy 211, 109203 , 2026
2026
Citations: 1
Time-resolved co-fermentation dynamics: Optimizing fermentation time for energy-efficient lignocellulosic ethanol production from oil palm empty fruit bunches
Y Niu, Y Wang, N Joseph, AK Abiodun, CP Leh, CK Lee
Energy for Sustainable Development 92, 101922 , 2026
2026
Citations: 4
Genome sequencing of endophytic bacterial species associated with Datura stramonium and Sida acuta
SA Ayoola, AK Ajijolakewu, AE Ajadi, RF Zakariyah, MO Kazeem, ...
Microbes and Infectious Diseases 7 (2), 1588-1595 , 2026
2026
Restoration of the Viability and Bioactivity of Endophytic Fungi Using Epigenetic Modification
RF Zakariyah, EP Samuel, KA Ajijolakewu, AS Ayoola, RN Ahmed, ...
The Microbe, 100704 , 2026
2026
In silico evaluation of bioactive compounds from endophytic Nigrospora oryzae UILRZ1 as potential inhibitors of clinically relevant resistant bacterial targets
RF Zakariyah, RN Ahmed, KA Ajijolakewu, IO Oladunjoye, EP Samuel
Medicine in Omics, 100056 , 2026
2026
Controlled Release of Antimicrobial Biomolecules by Plant-Based Nanomaterials
SA Ayoola, AK Ajijolakewu, AE Ajadi, AO Asuku, SB Adamu
Applications of Plant Bioactive Compounds-Based Nanoformulations … , 2026
2026
Citations: 1
Molecular Phylogenetics of Dominant Endophytic Fungi in Leaves of Vitellaria Paradoxa Using Internal Transcribed Spacer Gene Region
A Lateef, AKO AbdulMalik, FT Mustapha, BB Tiamiyu, KA Ajijolakewu
Journal of Science and Technology 17 (2), 1-12 , 2025
2025
Antimicrobial Potentials of Sida acuta Leaf Extracts on Some Resistant Bacterial Isolates
AK Ajijolakewu, SA Ayoola, AE Ajadi, RF Zakariyah, MO Kazeem
Nigerian Journal of Parasitology 46 (2), 190-198 , 2025
2025
Bio-prospecting locally relevant industrial yeast strains from fermented carbohydrate-rich food waste from Nigeria
MO Kazeem, SO Olabamiji, KA Ajijolakewu, HS Hafid
Iraqi Journal of Science, 90-102 , 2025
2025
Citations: 1
Genome sequencing of endophytic bacterial species associated with Datura stramonium and Sida acuta
RF Zakariyah, KA Ajijolakewu, SA Ayoola, AE Ajadi, MO Kazeem, ...
Zagazig University , 2025
2025
ENHANCED ANTIBACTERIAL POTENTIAL OF FRACTIONATED BIOACTIVE COMPOUNDS ISOLATED FROM ENDOPHYTIC NIGROSPORA ORYZAE UILRZ1 IN OCIMUM GRATISSIMUM
FZ RAHMAT, NA RISIKAT, AA KAMOLDEEN, AH ABDULMUMEEN
JOURNAL OF TROPICAL BIODIVERSITY AND BIOTECHNOLOGY 10 (1) , 2025
2025
Citations: 3
Enhanced Antibacterial Potential of Fractionated Bioactive Compounds Isolated from Endophytic Nigrospora oryzae UILRZ1 in Ocimum gratissimum
RF Zakariyah, RN Ahmed, KA Ajijolakewu, AA Hamid
Journal of Tropical Biodiversity and Biotechnology 10 (1), 12019-12019 , 2025
2025
Phytochemical Profiling, GC-MS Analysis and Antibacterial Activity of Sida acuta leave Extracts against Helicobacter pylori
AK Ajijolakewu, AE Ajadi, SA Ayoola, SI Bale, TA Sorunke, SA Onifade, ...
UMYU Journal of Microbiology Research (UJMR) 9 (2), 149-158 , 2024
2024
Citations: 3
In vitro IN VITRO EVALUATION OF THE ANTIBACTERIAL EFFICACY OF DATURA STRAMONIUM LEAF AGAINST HELICOBACTER PYLORI
AE Ajadi, AK Ajijolakewu, SA Ayoola, MY Omotunde, BA Aguda
FUDMA JOURNAL OF SCIENCES 8 (6), 240-247 , 2024
2024
Citations: 1
Structural characterization and evaluation of mycogenic zinc oxide nanoparticles from the cell-free culture-extract of Aspergillus niger
AK Ajijolakewu, MO Kazeem, GM Dovia, IA Adebayo, ...
Ife Journal of Science 26 (1), 131-143 , 2024
2024
Citations: 1
Progress in endophytic fungi secondary metabolites: biosynthetic gene cluster reactivation and advances in metabolomics
RF Zakariyah, KA Ajijolakewu, AJ Ayodele, BI Folami-A, EP Samuel, ...
Bulletin of the National Research Centre 48 (1), 44 , 2024
2024
Citations: 35
Effects of dietary xylanase-treated rice husk on performance characteristics of West African Dwarf goats Capra hircus.
IO Kolade, MB Yousuf, AO Salako, KA Ajijolakewu, TZ Abdulkareem, ...
Aceh Journal of Animal Science 9 (1) , 2024
2024
Citations: 1
Therapeutic potential of secondary metabolites from endophytic fungi in biotechnology and medicine
AE Ajadi, AK Ajijolakewu, TA Sorunke, MM Suleiman, SA Ayoola, ...
Nigerian Journal of Pure and Applied Sciences, 4887-4909 , 2024
2024
Citations: 8
Molecular Characterization of Fungi Associated with Pod Rot of the African Locust Beans (Parkia biglobosa)
AMAO Lateef A. A, Naher L., Abdulkareem M. A, Ajijolakewu K. A
BIMA JOURNAL OF SCIENCE AND TECHNOLOGY 8 (3B), 260-270 , 2024
2024
Nig. J. Pure & Appl. Sci. Vol. 37 (Issue 1, 2024) e-ISSN 2756-4045 (C) 2024 Faculty of Physical Sciences and Faculty of Life Sciences, Univ. of Ilorin, Nigeria www. njpas. com. ng
AE Ajadi, AK Ajijolakewu, TA Sorunke, MM Suleiman, SA Ayoola, ...
2024

MOST CITED SCHOLAR PUBLICATIONS

A review of the ethnomedicinal, antimicrobial, and phytochemical properties of Musa paradisiaca (plantain)
KA Ajijolakewu, AS Ayoola, TO Agbabiaka, FR Zakariyah, NR Ahmed, ...
Bulletin of the National Research Centre 45 (1), 86 , 2021
2021
Citations: 76
Preparation and fundamental characterization of cellulose nanocrystal from oil palm fronds biomass
R Dungani, AF Owolabi, CK Saurabh, HPS Abdul Khalil, PM Tahir, ...
Journal of Polymers and the Environment 25 (3), 692-700 , 2017
2017
Citations: 71
Adsorption of cadmium and lead from palm oil mill effluent using bone-composite: Optimisation and isotherm studies
A Abdulrahman Oyekanmi, AA Abd Latiff, Z Daud, ...
International Journal of Environmental Analytical Chemistry 99 (8), 707-725 , 2019
2019
Citations: 63
Enhanced ethanol production from mild alkali-treated oil-palm empty fruit bunches via co-fermentation of glucose and xylose
AA Kamoldeen, CK Lee, WNW Abdullah, CP Leh
Renewable Energy 107, 113-123 , 2017
2017
Citations: 59
Optimization of production conditions for xylanase production by newly isolated strain Aspergillus niger through solid state fermentation of oil palm empty fruit bunches
AK Ajijolakewu, CP Leh, WNW Abdullah, C keong Lee
Biocatalysis and Agricultural Biotechnology 11, 239-247 , 2017
2017
Citations: 55
Benefits and limitations of phytoremediation: Heavy metal remediation review
AO Adeoye, IA Adebayo, AM Afodun, KA Ajijolakewu
phytoremediation, 227-238 , 2022
2022
Citations: 46
Progress in endophytic fungi secondary metabolites: biosynthetic gene cluster reactivation and advances in metabolomics
RF Zakariyah, KA Ajijolakewu, AJ Ayodele, BI Folami-A, EP Samuel, ...
Bulletin of the National Research Centre 48 (1), 44 , 2024
2024
Citations: 35
Characterization of novel Trichoderma hemicellulase and its use to enhance downstream processing of lignocellulosic biomass to simple fermentable sugars
KA Ajijolakewu, CP Leh, CK Lee, WAW Nadiah
Biocatalysis and Agricultural Biotechnology 11, 166-175 , 2017
2017
Citations: 31
Soil screening for antibiotic-producing microrgansms
AP Microrgansms
Advances in Environmental Biology 7 (1), 7-11 , 2013
2013
Citations: 27
Comparative antibacterial efficacy of Vitellaria paradoxa (Shea Butter Tree) extracts against some clinical bacterial isolates
KA AJIJOLAKEWU, FJ AWARUN
Notulae Scientia Biologicae 7 (3), 264-268 , 2015
2015
Citations: 23
Assessment of the effect of easily-metabolised carbon supplements on xylanase production by newly isolated Trichoderma asperellum USM SD4 cultivated on oil …
KA Ajijolakewu, LCP Leh CheuPeng, WA Wan Nadiah, ...
2016
Citations: 20
Antimicrobial effects of Garcinia Kola (bitter kola) on some selected pathogens from University of Ilorin Teaching Hospital Ilorin, Nigeria
MO Arekemase, AM Babandoko, KRM Ojo, AA Elizabeth, AA Kamoldeen
Journal of Asian Scientific Research 2 (4), 159 , 2012
2012
Citations: 19
Optimisation of Lactic Acid Fermentation from Cassava Peel by Lactobacillus casei (ATCC334)
RF Zakariyah, MO Ojo, KA Ajijolakewu, KB Saliu, RN Ahmed, ...
Microbiology Research Journal International 31 (6), 29-42 , 2021
2021
Citations: 14
Cellulase production by co-culture of Bacillus licheniformis and B. paralicheniformis over monocultures on microcrystalline cellulose and chicken manure-supplemented rice bran …
M Kazeem, K Ajijolakewu, NA Rahman
BioResources 16 (4), 6850 , 2021
2021
Citations: 12
Phytoremediation
AO Adeoye, IA Adebayo, AM Afodun, KA Ajijolakewu
Academic Press , 2022
2022
Citations: 10
Therapeutic potential of secondary metabolites from endophytic fungi in biotechnology and medicine
AE Ajadi, AK Ajijolakewu, TA Sorunke, MM Suleiman, SA Ayoola, ...
Nigerian Journal of Pure and Applied Sciences, 4887-4909 , 2024
2024
Citations: 8
SCREENING FOR XYLOSYL HYDROLASE (XYLANASE) ENZYMES IN SOIL FUNGAL SPECIES; COMPARATIVE EFFICACY OF SOLID STATE FERMENTATION TECHNIQUE AND PLATE-SCREENING METHODS.
AK Abiodun, LC Peng, WNW AbduLLah, L Chee
Exploring the Frontiers in Environmental Science and Technology Research … , 2015
2015
Citations: 8
Cellulase production potentials of the microbial profile of some sugarcane bagasse dumping sites in Ilorin, Nigeria
KA AJIJOLAKEWU, S Alhasan, GP OYEYIOLA, RN AHMED, ...
Notulae Scientia Biologicae 5 (4), 445-449 , 2013
2013
Citations: 8
Assessment and biological treatment of effluent from a pharmaceutical industry
GB Adebayo, OM Kolawole, AK Ajijolakewu, SO Abdulrahaman
Annals of Biological Research 1 (4), 28-33 , 2010
2010
Citations: 8
Worldwide prevalence of aflatoxins in food and feed
YO Oyebamiji, KA Ajijolakewu, IA Adebayo
Aflatoxins in food: a recent perspective, 41-65 , 2022
2022
Citations: 6

Ajijolakewu Kamoldeen

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Scopus Publications

RECENT SCHOLAR PUBLICATIONS

MOST CITED SCHOLAR PUBLICATIONS