Jeetendra Kumar Gupta

Scopus Publications

Reteplase at the Molecular Interface: Mechanisms and Therapeutic Impact in Myocardial Infarction and Stroke
Jeetendra Kumar Gupta
Research Journal of Biotechnology, 2026
Reteplase, a recombinant plasminogen activator, is a modified version of Tissue-Plasminogen Activator (tPA). It has an altered structure, retaining Kringle 2 and Protease domains but lacks Finger, Epidermal Growth Factor (EGF) and Kringle 1 domains. The design of this molecule has provided Reteplase with certain advantages including longer half-life in the plasma (13–16 min.), lower fibrin affinity allowing for better clot penetration and non-glycosylated state allowing it to be administered by two boluses (usually 18 mg+18 mg, 30 min apart) regardless of body size. The molecular interactions at the interface between Reteplase and fibrin in clots provide a catalytic site for the activation of plasminogen to plasmin, resulting in degradation of the fibrin network and restoration of blood flow through the affected vessels. In comparison to Alteplase, Reteplase has shown earlier initiation of thrombolytic activity and possibly a higher rate of recanalization due to structural changes. Most recently, in patients with Acute Ischemic Stroke, the phase III RAISE Trial (2024) demonstrated that Reteplase was superior to Alteplase when administered less than or equal to 4.5 hrs post onset of symptoms, resulting in good functional outcomes. These results suggest that the primary mechanism for the observed benefits of Reteplase may be due to improved early recanalization. This review will discuss the molecular mechanisms of action, pharmacokinetics and expanding clinical use of Reteplase in Acute Myocardial Infarction (AMI) and Acute Ischemic Stroke, with particular emphasis on how Reteplase may be used to increase access to thrombolysis therapy in resource-poor areas while continuing to address issues of optimal dosing and expanded global availability.
Novel Cellular Signalling Axes in Neurodegenerative Diseases: From NLRP3 Inflammasome to Wnt/β-Catenin and Hippo-YAP Pathways
Kuldeep Singh, Iftakhar Ahmad, Divya Jain, Tasmia Jahin Mim, Abdullah Al Noman, Md. Piar Rahaman Shihab, Suresh Babu Kondaveeti, Jeetendra Kumar Gupta, Pranay Wal
Journal of Biochemical and Molecular Toxicology, 2026
Neurodegenerative diseases (NDs), including Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), and Parkinson's disease (PD), are characterised by impaired cellular homeostasis and progressive neuronal loss. Emerging evidence highlights the critical role of cellular signalling pathways in the progression and pathogenesis of these disorders. With a focus on the NLRP3 inflammasome, Wnt/β‐catenin, and Hippo‐YAP cascades, this review focuses on new signalling pathways linked to neurodegenerative disorders. Among them, the NLRP3 inflammasome is a crucial mediator of neuroinflammation, causing neuronal damage and persistent immune activation. In contrast, these pathways regulate neurogenesis, synaptic plasticity, and cell survival, offering potential neuroprotective functions. Dysregulation of these pathways disrupts cellular integrity, exacerbates disease progression, and represents a convergence point for therapeutic intervention. In NDs, knowing how these pathways interact offers fresh perspectives on disease processes and finds new targets for the creation of disease‐modifying treatments.
Targeting NF-κB and JAK/STAT pathways in rheumatoid arthritis: emerging nanocarrier-based drug delivery approaches
G. Surendra, Jeetendra Kumar Gupta, E. Susithra, A. C. Jesudoss Prabhakaran, A. Jasmine Chandra, Vijayakumar Subash, Thukani Sathanantham Shanmugarajan, Uppuluri Varuna Naga Venkata Arjun, Konatham Teja Kumar Reddy, Ramana Hechhu
Inflammopharmacology, 2026
A Review on Neolamarckia cadamba - From Its Ancient Knowledge to Modern Science
Ravindra Mishra, Jeetendra Kumar Gupta
Current Drug Therapy, 2026
 In the herbal medicine system, N. cadamba is one of the most significant plants in the Rubiaceae family. N. cadamba contains numerous phytochemicals and secondary metabolites, in-cluding β-sitosterol, quinovic acid, cadambagenic acid, cadamine, and cadambine, which exhibit pharmacological and biological effects, making it a highly valuable medicinal plant. N. cadamba has demonstrated potential in managing conditions such as diabetes, epilepsy, hypertension, and other disorders, offering a natural alternative to synthetic chemical treatments. Over a century of research has been conducted to identify its phytochemicals and their effects. How-ever, due to a lack of appropriate model systems, only a small percentage (≤2%) of these compounds have been successfully marketed. Beyond its medicinal properties, N. cadamba is also valued as an ornamental plant with considerable cultural and religious importance. To stimulate interest and support the commercialization of N. cadamba phytochemicals, this review consolidates current knowledge on these compounds and highlights their pharmacological signifi-cance. By addressing the challenges of commercialization, including contentious issues, model sys-tem inadequacies, and solubility problems, the potential of N. cadamba as a cornerstone in herbal medicine can be fully realized. This comprehensive understanding and subsequent application could transform treatment options, providing natural and effective alternatives for managing and potentially curing various diseases.
Decoding microRNA-Protein Interaction Networks in Alzheimer’s Disease: Molecular Mechanisms and Clinical Implications
Ravindra Mishra, Jeetendra Kumar Gupta
Current Alzheimer Research, 2026
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and neuronal dysfunction. Despite thorough research efforts, effective disease-modifying treatments have yet to be discovered. MicroRNAs (miRNAs), small noncoding RNAs that control gene expression after transcription, have become key factors in AD development. Changes in miRNA levels influence critical molecular pathways such as amyloid precursor protein (APP) processing, tau phosphorylation, oxidative stress, neuroinflammation, and synaptic plasticity, all of which contribute to neuronal damage. By increasing β-secretase (BACE1) activity, downregulation of miR-29a/b and miR-107 encourages the buildup of amyloid-β (Aβ) and the development of plaques. Through the deregulation of the CDK5 and MAPK pathways, overexpression of miR-125b and decreased levels of miR-132/212 lead to tau hyperphosphorylation. While oxidative stress-associated miRNAs like miR-34a and miR- 21 worsen mitochondrial malfunction and neuronal death, pro-inflammatory miRNAs like miR-146a and miR-155 cause NF-κB-mediated signalling and glial activation. Circulating miRNAs found in blood and cerebral fluid are potential, minimally invasive indicators for tracking the course of a disease and making early diagnoses. Additionally, therapeutic manipulation with antagomiRs or miRNA mimics has the potential to prevent neurodegeneration and restore normal gene regulation. This review deciphers the molecular mechanisms underlying miRNA dysregulation in AD and explores their translational potential as biomarkers and therapeutic targets. A comprehensive understanding of miRNA-protein interaction networks could facilitate the development of targeted, precision- based interventions for Alzheimer’s disease.
A review on artificial intelligence in pharmaceutical sciences: opportunities and challenges
Vivek Kumar, Saurav Kumar, Ravi Kumar, Nidhi Tiwari, Jeetendra Kumar Gupta
Drug Development and Industrial Pharmacy, 2026
SIGNIFICANCE: The review aims to systematically explore the transformative impact of artificial intelligence (AI) on pharmaceutical sciences. It addresses key research questions regarding how AI accelerates drug development, enhances clinical trial design, optimizes manufacturing, and drives advances in personalized and precision medicine. METHODS: A comprehensive literature review was conducted. It synthesized recent studies, industry reports, and regulatory guidelines on AI adoption. Covered drug discovery, clinical trials, pharmacovigilance, manufacturing, supply chain management, and pharmacy education. It also critically examined barriers such as data quality, privacy, explainability, and the evolving regulatory landscape. RESULTS: AI accelerates pharmaceutical R&D, identification, lead optimization, ADMET (absorption, distribution, metabolism, excretion, toxicity) prediction, drug repurposing, and clinical trial analytics. It enables faster and more cost-effective development. Advancements in personalized medicine and individualized patient data are driving better patient outcomes. The students still ace continuing challenges in data interpretation, privacy, and regulatory issues. CONCLUSIONS: Ongoing AI advancements and evolving regulations are set to revolutionize pharmaceutical science. They will enable efficient, predictive, and patient-centered healthcare. Success will depend on integrating multi-omics, adopting explainable AI, and fostering collaboration among all stakeholders. Ultimately, AI promises safer, faster, and more precise drug delivery system. It benefits clinicians, researchers, and students.
Pharmacological Approaches and Innovative Strategies for Individualized Patient Care
Amnesh Kumar Verma, Kuldeep Singh, Jeetendra Kumar Gupta, Shivendra Kumar, Divya Jain
Recent Patents on Biotechnology, 2026
Personalized medicine is an evolving paradigm that aims to tailor therapeutic interventions to individual patient characteristics. With a growing understanding of the genetic, epigenetic, and molecular mechanisms underlying diseases, tailored therapies are becoming more feasible and effective. This review highlights the significant advancements in personalized medicine, focusing specifically on pharmacological strategies. The article explores the integration of genomics, transcriptomics, proteomics, and metabolomics in drug development and therapy optimization. Pharmacogenomics, the customization of drug therapy based on an individual's genetic makeup, receives particular emphasis. This leads to the identification of specific biomarkers that can predict therapeutic response, drug toxicity, and susceptibility to various diseases. Together with computational tools and artificial intelligence, these advancements contribute to tailored treatment plans for patients with conditions such as cancer, cardiovascular diseases, and neurological disorders. We also highlight the challenges and ethical considerations in implementing personalized medicine, such as data privacy, cost-effectiveness, and accessibility. We outline future prospects and ongoing research in this field, highlighting the importance of collaborative efforts between researchers, clinicians, pharmacists, and regulatory authorities.
Efficacy of Anti-Histaminic Agents in Asthma Management: A Critical Scientific Analysis
Ekta Verma, Shweta Mishra, Jeetendra Kumar Gupta, Saheli Roy, Pranay Wal, Adarsh Sahu
Combinatorial Chemistry and High Throughput Screening, 2026
Introduction: Allergic asthma is triggered by allergens and is commonly associated with elevated IgE levels. Histamine plays a pivotal role in its pathogenesis; however, the therapeutic role of antihistamines remains controversial. Since current treatments primarily provide symptomatic relief, this review evaluates the current status of antihistamines in asthma management, with a focus on pharmacological advances, natural therapies, and novel heterocyclic compounds. Method: A comprehensive literature search was systematically conducted across major databases, including PubMed, ScienceDirect, Scopus, and Web of Science. Studies evaluating the pharmacological potential of antihistamines, herbal compounds, and novel synthetic derivatives were included. Exclusion criteria encompassed studies unrelated to asthma or antihistamines, non-English publications, and editorials or conference abstracts lacking primary data. Results: Second- and third-generation antihistamines effectively alleviate symptoms of allergic asthma and can reduce corticosteroid use. Combining antihistamines with leukotriene receptor antagonists has been shown to further enhance treatment outcomes. Emerging evidence also suggests that heterocyclic compounds and plant-derived phytochemicals may serve as promising antihistamines and bronchodilators, although their clinical application remains limited. Discussion: Modern antihistamines provide added value as supportive agents in asthma management, particularly for allergic subtypes. Their improved pharmacological profiles reduce sedation and enhance patient compliance. The synergistic use of antihistamines with corticosteroids or leukotriene inhibitors exemplifies a shift toward multimodal therapy, while novel compounds continue to broaden therapeutic possibilities. Conclusion: Antihistamines are increasingly recognized as valuable adjuvants in asthma management. Although asthma remains incurable, advanced antihistamines and natural phytochemicals provide effective symptom relief. Continued research into novel compounds and integrated therapeutic strategies holds promise for improved disease control and enhanced quality of life.
Biogenic Synthesis of SnO2 Nanoparticles Using Albizia saman Leaf Extract for Visible Light-Driven Photocatalytic Dye Degradation and Antibacterial Applications
C. Parvathiraja, K. Paulkumar, Jeetendra Kumar Gupta, Lofti Mouni, Tahani Mazyad Almutairi, Van-Huy Nguyen
Arabian Journal for Science and Engineering, 2026
A comprehensive review of drug-resistant epilepsy and animal models: Existing and emerging therapies and future research directions
Aman Shrivastava, Jeetendra Kumar Gupta, Sumeet Dwivedi, Amit Anand, Darshana Sharma, Sonam Upadhyay, Prerna Chaturvedi
Advanced Neurology, 2026
Epilepsy is a long-term neurological disorder that results in recurring, uncontrolled seizures. These kinds of seizures are caused by excessively high and irregular electrical discharge in the central nervous system. Epilepsy is among the most common neurological disorders, with approximately 50–70 new cases/100,000 people every year. This review critically examines the current landscape of pharmacological experimental animal models employed in the study of drug-resistant and refractory epilepsy, shedding light on the complexities of this multifaceted disorder. Through an extensive analysis of preclinical models, the review explores the diverse mechanisms underlying resistance to antiepileptic drugs, emphasizing the need for innovative therapeutic strategies. This review was conducted using a comprehensive search of databases, including PubMed, Scopus, and Web of Science, focusing on studies published from 2000 to 2024. Articles were selected based on relevance to drug-resistant epilepsy (DRE) models, emerging technologies, and translational potential, using keywords such as DRE, animal models, and epileptogenesis. In addition, emerging experimental approaches, such as optogenetics, chemogenetics, and advanced imaging techniques, were scrutinized. Furthermore, this review outlines innovative approaches, including novel pharmacotherapies, gene therapies, and precision medicine interventions, that hold promise for overcoming drug resistance. By synthesizing current knowledge and identifying gaps, this article aims to guide future research directions and stimulate innovative strategies for developing effective interventions for drug-resistant and refractory epilepsy. Ultimately, a comprehensive grasp of experimental models and innovative approaches is crucial for advancing our understanding of epilepsy pathophysiology and paving the way for more efficacious and personalized therapeutic interventions.
NF-κB Signaling Pathway: A Central Hub in the Pathogenesis and Therapeutic Targeting of Immunological Diseases
Yati Sharma, Aman Shrivastava, Jeetendra Kumar Gupta, Rashmi Mishra, Abhishek Dwivedi, Prerna Chaturvedi, Sumeet Dwivedi
Gene Expression, 2026
Transforming RNA-Based Gene Therapy with Innovative Nanocarriers for siRNA and miRNA Delivery
Jitendra Singh Chaudhary, Dilip Kumar Chanchal, Kuldeep Singh, Jeetendra Kumar Gupta, Divya Jain, Anubhav Dubey, Mahima Pandey, Shahbaz Khan
Current Gene Therapy, 2026
Insights into the Molecular Mechanisms of Neurodegenerative Diseases: Exploring Molecular Pathways and the Therapeutic Potential of Rivastigmine
Kuldeep Singh, Pranshul Sethi, Mamta Kumari, Jeetendra Kumar Gupta, Zaid Waqar, Divya Jain, Aakansha Verma, Alok Bhatt, Mukesh Chandra Sharma
CNS and Neurological Disorders Drug Targets, 2026
Advances in the Synthesis of GABAergic Modulators for Anxiety and Depression: Pathways and Potential Applications
Kuldeep Singh, Pranshul Sethi, Divya Jain, Jeetendra Kumar Gupta, Omar Awad Alsaidan, Sami I. Alzarea, Anubhav Dubey, Mohammad Tabish, Rajagopalan Ramanathan
Current Neuropharmacology, 2026
The RhoA/ROCK pathway in vascular dysfunction and inflammation: Mechanisms and therapeutic targeting
Kuldeep Singh, Divya Jain, Arpan Kumar Tripathi, Touseef Begum, Mohammad Muztaba, Shamim Shamim Khan, Jeetendra Kumar Gupta, Abdullah Al Noman, Mukesh Chandra Sharma, Pranab Dev Sharma
European Journal of Inflammation, 2026
Gamma irradiation crosslinked fluorescent nanocarbon based biodegradable hydrogel for controlled release of antibiotics
Rajeshwar Vodeti, Mokhtar Rejili, Venkata Ramana Singamaneni, Umme Hani, Farhat Fatima, Jeetendra Kumar Gupta, Patibandla Jahnavi, Ramenani Hari Babu, Sharuk L. Khan, Md. Faysal
Plos One, 2026
Molecular Mechanisms of Neurodegeneration: A Focus on Cholinergic Dysfunction and the Therapeutic Potential of Rivastigmine Derivatives
Kuldeep Singh, Pranshul Sethi, Divya Jain, Jeetendra Kumar Gupta, Zaid Waqar, Bhupendra Singh, Rukhsar Syed, Mohammad Tabish, Mukesh Chandra Sharma
Current Topics in Medicinal Chemistry, 2026
Fisetin and Neurodegeneration: From Preclinical Studies to Potential Clinical Applications
Md. Al Amin, Mehrukh Zehravi, Sherouk Hussein Sweilam, Ronald Darwin, Jeetendra Kumar Gupta, E. Bhargav, G. Dharmamoorthy, Voleti Vijaya Kumar, A. Anka Rao, Muath Suliman, Thirunavukkarasu Periyasamy, Talha Bin Emran
CNS and Neurological Disorders Drug Targets, 2026
Advances in polymeric nanoparticles for oral drug delivery: mechanisms, challenges, emerging trends, and preclinical to clinical perspectives
Mehrukh Zehravi, Sharuk L. Khan, Jeetendra Kumar Gupta, Patibandla Jahnavi, Ramenani Hari Babu, Nithin Vidiyala, Anuradha Averineni, G. Dharmamoorthy, Venkata Lakshamana Sagar Dantinapalli, Selvaraja Elumalai, Safia Obaidur Rab, Talha Bin Emran
3 Biotech, 2026
Advances in nanomedicine strategies for modulating the tumor microenvironment: Recent progress and clinical perspectives
Talha Bin Emran, Md. Al Amin, Safia Obaidur Rab, Patibandla Jahnavi, Rajeshwar Vodeti, Jeetendra Kumar Gupta, Uppuluri Varuna Naga Venkata Arjun, T. N. Umamaheswari, P. Balaji, Girija Dayalan, Soniya Rani, Prem Shankar Gupta
3 Biotech, 2026
Quercetin and Cancer: Molecular Mechanisms and Signaling Pathway Modulation for Therapeutic Benefits
Md. Al Amin, Mehrukh Zehravi, Hasna Bouhenni, Kurratul Aiun Siddika, Jeetendra Kumar Gupta, Rajeshwar Vodeti, Uppuluri Varuna Naga Venkata Arjun, Patibandla Jahnavi, Gayathri K, Ramenani Hari Babu, Abdul Ajeed Mohathasim Billah, P. Dharani Prasad, Safia Obaidur Rab, Koula Doukani, Talha Bin Emran
Current Topics in Medicinal Chemistry, 2026
Stilbenes in cancer therapy: insights into molecular targets, and advances towards clinical application
Fahadul Islam, Mehrukh Zehravi, M. Raju Molla, Sherouk Hussein Sweilam, Patibandla Jahnavi, Om Mahadeo Bagade, Jeetendra Kumar Gupta, Rajeshwar Vodeti, Karthickeyan Krishnan, Vasudha Bakshi, P. Dharani Prasad, Muath Suliman, Mst. Nowsad Zahan Sathi, Talha Bin Emran
Medical Oncology, 2025
Multiple sclerosis: a comprehensive review of pathophysiology and combined natural-synthetic therapeutic strategies
Md. Al Amin, Mehrukh Zehravi, Sherouk Hussein Sweilam, M. Raju Molla, Patibandla Jahnavi, Om M. Bagade, Jeetendra Kumar Gupta, A. Anka Rao, Karthickeyan Krishnan, Rajeshwar Vodeti, P. Dharani Prasad, Irfan Ahmad, Koula Doukani, Talha Bin Emran
3 Biotech, 2025
Combination of metal oxides (TiO2/WO3/CeO2) based nanocomposites for photocatalytic application of a harmful environmental depravation
Anugraha Ganapathy rama Subramanian, Balu Thangaraj, Nagarajan Muthukurumban, Jeetendra Kumar Gupta, Parvathiraja Chelliah
Journal of the Indian Chemical Society, 2025
Therapeutic potential and molecular mechanisms of natural flavonoids in liver cancer
Rohit Tripathi, Arpita Yadav, Avadh Biharee, Jeetendra Kumar Gupta, Bhupendra Singh, Prateek Pathak, Chiagoziem A. Otuechere, Amita Verma
Pharmacological Research Natural Products, 2025
Natural Agents Modulating Ferroptosis in Cancer: Molecular Pathways and Therapeutic Perspectives
Md. Al Amin, Mehrukh Zehravi, Sherouk Hussein Sweilam, Patibandla Jahnavi, Jeetendra Kumar Gupta, Varikalla Rajashakar, Rajeshwar Vodeti, Abdul Ajeed Mohathasim Billah, G. Dharmamoorthy, Uppuluri Varuna Naga Venkata Arjun, Voleti Vijaya Kumar, Muath Suliman, Talha Bin Emran
Journal of Cellular and Molecular Medicine, 2025
Therapeutic approach for triple-negative breast Cancer through poly (ADP-ribose) Polymerase-1 inhibitors: Current update
Agnidipta Das, Sudip Kumar Mandal, Swati Arya, Samir Kumar Samanta, Ashok Kumar, Mitali Panchpuri, Hassan Abdel-Gawad, Vagish Dwibedi, Niranjan Das, Sankhadip Bose, Jeetendra Kumar Gupta, Vikas Jaitak, Santosh Kumar Rath
Bioorganic Chemistry, 2025
Alkaloids as neuroprotectors: targeting signaling pathways in neurodegenerative diseases
Biswajit Kumar Utpal, Md Al Amin, Mehrukh Zehravi, Sherouk Hussein Sweilam, Uppuluri Varuna Naga Venkata Arjun, Y. Bala Madhuri, Jeetendra Kumar Gupta, Lavanya Yaidikar, Tanuja Tummala, R. Suseela, Akiladevi Durairaj, Konatham Teja Kumar Reddy, Ali Audah Fahaid Al Fahaid, Safia Obaidur Rab, Mohammed Saeed Almahjari, Talha Bin Emran
Molecular and Cellular Biochemistry, 2025
Advances in viral vector-based delivery systems for gene therapy: a comprehensive review
Kuldeep Singh, Divya Jain, Pranshul Sethi, Jeetendra Kumar Gupta, Anubhav Dubey, Abdullah Al Noman, Shipra lal, Pranab Dev Sharma, Emad M. Abdallah
3 Biotech, 2025
Therapeutic potential of flavonoids in neuroprotection: brain and spinal cord injury focus
Md. Faysal, Md Al Amin, Mehrukh Zehravi, Sherouk Hussein Sweilam, Uppuluri Varuna Naga Venkata Arjun, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Sarandeep Shanmugam Prakash, Girija Dayalan, Saravanakumar Kasimedu, Y Bala Madhuri, Konatham Teja Kumar Reddy, Safia Obaidur Rab, Ali Audah Fahaid Al Fahaid, Talha Bin Emran
Naunyn Schmiedeberg S Archives of Pharmacology, 2025
Phytochemical-Based Drug Discovery for Breast Cancer: Combining Virtual Screening and Molecular Dynamics to Identify Novel Therapeutics
Trupti Pratik Durgawale, V. Rajashakar, Jeetendra Kumar Gupta, S. Shakila Banu, Sri Hari Galla, Jyoti Singh, A. Anka Rao, P. Dharani Prasad, Pritam Bhagawat Chaudhari, Mohammad Rakib Mortuza, Sherouk Hussein Sweilam, Mohammed Asiri, Md Al Amin, Biswajit Kumar Utpal, Badrud Duza Mohammad
Chemistry and Biodiversity, 2025
Natural products as drug leads: exploring their potential in drug discovery and development
Kuldeep Singh, Jeetendra Kumar Gupta, Dilip Kumar Chanchal, Manoj Gangadhar Shinde, Shivendra Kumar, Divya Jain, Zainab M. Almarhoon, Asma M. Alshahrani, Daniela Calina, Javad Sharifi-Rad, Anjali Tripathi
Naunyn Schmiedeberg S Archives of Pharmacology, 2025
Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection
Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran
Animal Models and Experimental Medicine, 2025
Resveratrol: A Natural Compound Targeting the PI3K/Akt/mTOR Pathway in Neurological Diseases
Biswajit Kumar Utpal, Fatima Zohra Mokhfi, Mehrukh Zehravi, Sherouk Hussein Sweilam, Jeetendra Kumar Gupta, Shaik Kareemulla, Ronald Darwin. C, A. Anka Rao, Voleti Vijaya Kumar, Pavankumar Krosuri, Dharani Prasad, Sharukh L. Khan, Sajib Chandra Roy, Safia Obaidur Rab, Mohammed Ali Alshehri, Talha Bin Emran
Molecular Neurobiology, 2025
Exploring synergistic benefits and clinical efficacy of turmeric in management of inflammatory and chronic diseases: A traditional Chinese medicine based review
Divya Jain, Kuldeep Singh, Paras Gupta, Jeetendra Kumar Gupta, Pankaj Kumar Sahu, Sumeet Dwivedi, Mukesh Chandra Sharma, Shivendra Kumar
Pharmacological Research Modern Chinese Medicine, 2025
Revolutionizing Diabetes Care: The Role of Marine Bioactive Compounds and Microorganisms
Konatham Teja Kumar Reddy, Kamsali Rakesh, Segu Prathyusha, Jeetendra Kumar Gupta, Kasturi Nagasree, R. Lokeshvar, Selvaraja Elumalai, P. Dharani Prasad, Deepti Kolli
Cell Biochemistry and Biophysics, 2025
Progress of Indole Alkaloids for Potential Application in Type 2 Diabetes Mellitus-An Updated Review
Biointerface Research in Applied Chemistry, 2025
Efficient Deep Learning Model for Analyzing Muscle Activity Patterns in Biomechanical Simulations
Dharmendra Dangi, Dheeraj Kumar Dixit, Amit Bhagat, Durgesh Rao, Jeetendra Kumar Gupta
SN Computer Science, 2025
AI-driven insights into the microbiota: Figuring out the mysterious world of the gut
Abhinandan Patil, Neha Singh, Mohsina Patwekar, Faheem Patwekar, Anasuya Patil, Jeetendra Kumar Gupta, Selvaraja Elumalai, Nagam Santhi Priya, Alapati sahithi
Intelligent Pharmacy, 2025
Exploring the neuroprotective benefits of phytochemicals extracted from indigenous edible fruits in Bangladesh
Sumon Roy, Sajib Chandra Roy, Mehrukh Zehravi, Sherouk Hussein Sweilam, Rajib Das, Mylsamy Palanisamy, Venkata Lakshamana Sagar Dantinapalli, Selvaraja Elumalai, Jeetendra Kumar Gupta, Mohammed Ali Alshehri, Mohammed Asiri, Irfan Ahmad, Mohamed H. Nafady, Talha Bin Emran
Animal Models and Experimental Medicine, 2025
Evaluation of in vitro Anti-Cancer Activity of Vinorelbine Ditartrate Loaded PLGA Chitosan Nanoparticles Using A549 Human Lung Cancer Cell Line
Varsha Bandil, Jeetendra Kumar Gupta
Indian Journal of Pharmaceutical Education and Research, 2025
Role of Brain Ang (1-7) with Combination Therapy of Aliskiren in Control of Diabetic Nephropathy
Richa Shakya, Jeetendra Kumar Gupta, Avijit Mazumder
Indian Journal of Pharmaceutical Education and Research, 2025
Antiasthamatic Activity of Betulinic Acid as a Current Bioactive Compound in an Experimental Model
Shiv Narayan, Jeetendra Kumar Gupta, Sudip Kumar Mandal
Current Bioactive Compounds, 2025
Understanding Mechanisms and Key Factors Influencing Melanogenesis for the Management of Melasma: An Updated Review
Niraj Kumar Singh, Amnesh Kumar Verma, Jeetendra Kumar Gupta
Current Pharmaceutical Biotechnology, 2025
Innovative Approaches in Molecular Docking for the Discovery of Novel Inhibitors Against Alzheimer's Disease
Bhoopendra Singh, Kuldeep Singh, Jeetendra Kumar Gupta, Bhupesh Chander Semwal, Divya Jain, Mukesh Chandra Sharma
Current Alzheimer Research, 2025
Bio-engineered NiO nanoparticles for photocatalytic and antibacterial treatments
V. Beena, C. Parvathiraja, K. Paulkumar, Jeetendra Kumar Gupta, Tahani Mazyad Almutairi, Lotfi Mouni
Journal of Dispersion Science and Technology, 2025
Exploring Therapeutic Frontiers: Unveiling the Potential of Natural Diterpenoid Derivatives in Addressing Neurological Disorders
Kuldeep Singh, Jeetendra Kumar Gupta, Divya Jain, Shivendra Kumar, Sunam Saha, Ashwani Sharma
Current Pharmaceutical Biotechnology, 2025
Advances in Artemisinin-based Therapies: Innovations in Synthesis, Drug Delivery, and Expanding Therapeutic Applications
Akshay Thakur, Gaurav Thakur, Vir Vikram Sharma, Kuldeep Singh, Jeetendra Kumar Gupta, Divya Jain, Mukesh Chandra Sharma
Recent Patents on Anti Cancer Drug Discovery, 2025
Advancements in Precision Oncology: Harnessing High-Throughput Screening and Computational Strategies for Targeted Cancer Therapies
Akshay Thakur, Kaunava Roy Chowdhury, Vir Vikram Sharma, Kuldeep Singh, Jeetendra Kumar Gupta, Divya Jain, Mukesh Chandra Sharma
Combinatorial Chemistry and High Throughput Screening, 2025
Exploring the Dual Roles of Neural Stem Cells in Glioblastoma: Therapeutic Implications and Opportunities
Kuldeep Singh, Pranshul Sethi, Jeetendra Kumar Gupta, Anubhav Dubey, Mukesh Chandra Sharma, Divya Jain, Alok Bhatt, Shivendra Kumar
Current Stem Cell Research and Therapy, 2025
Emulgel-Based Formulations of Clobetasol Propionate: Formulation Development, Characterization, and Pharmacological Evaluation
Kuldeep Singh, Jeetendra Kumar Gupta, Divya Jain, Mukesh Chandra Sharma, Shivendra Kumar, Ramkumar Chaudhary, Sakshi Mishra
Pharmaceutical Nanotechnology, 2025
Emerging Applications and Innovations in Emulgel Technology for Enhanced Topical Drug Delivery
Kuldeep Singh, Jeetendra Kumar Gupta, Shamim -, Mohammad Muztaba, Shaheena Sohi, Jailani. S, Mukesh Chandra Sharma, Divya Jain
Drug Delivery Letters, 2025
An Overview of the Pharmacological and Phytochemical Characteristics of Betula utilis
Sunam Saha, Yatin Kumar, Jeetendra Kumar Gupta, Shivendra Kumar, Kuldeep Singh, Talever Singh, Deepali Vij, Khushal Garg
Anti Infective Agents, 2025
Drug detection methods
Konatham Teja Kumar Reddy, Kurni Lakshmi Deepthi, Pavankumar Krosuri, Jeetendra Kumar Gupta, Mohana Vamsi Nuli, Venkata Lakshamana Sagar Dantinapalli, Selvaraja Elumalai, Karthickeyan Krishnan
Nanotechnology Based Sensing Platforms for Illicit Drugs, 2025
Molecular Mechanisms and Pathways of Mesenchymal Stem Cell-mediated Therapy in Brain Cancer
Kuldeep Singh, Geetanjali Singh, Jeetendra Kumar Gupta, Alka N Choudhary, Arun Kumar, Divya Jain, Mukesh Chandra Sharma, Shivendra Kumar
Current Stem Cell Research and Therapy, 2025
Advances in Molecular Docking Techniques for Targeting Protein Misfolding in Neurodegenerative Diseases
Kuldeep Singh, Jeetendra Kumar Gupta, Shiv Narayan, Ketki Rani, Divya Jain, Prateek Porwal, Mukesh Chandra Sharma, Shivendra Kumar
Current Pharmaceutical Biotechnology, 2025
Advance Nanotechnology-Based Drug Delivery Systems for Alzheimer's Disease: Advancements and Future Perspectives
Kuldeep Singh, Jeetendra Kumar Gupta, Gaurav Lakhchora, Divya Jain, Alok Bhatt, Mukesh Chandra Sharma, MVNL Chaitanya, Mohammad Tabish
Current Alzheimer Research, 2025
Challenges and future perspective of illicit drug sensors and strategies
Konatham Teja Kumar Reddy, G. Dharmamoorthy, Jeetendra Kumar Gupta, L. Karpagavalli, Selvaraja Elumalai, Shaik Kareemulla, M. Jeevitha, Karthickeyan Krishnan
Nanotechnology Based Sensing Platforms for Illicit Drugs, 2025
Exploring the Pharmacological Effects of Bioactive Peptides on Human Nervous Disorders: A Comprehensive Review
Kuldeep Singh, Jeetendra Kumar Gupta, Aman Shrivastava, Divya Jain, Amrendra Pratap Yadav, Sumeet Dwivedi, Anubhav Dubey, Shivendra Kumar
CNS and Neurological Disorders Drug Targets, 2025
Woodfordia fruticosa (L.) Kurz: An Evidence-based Study of its Phytochemical and Pharmacological Activities
Kuldeep Singh, Jeetendra Kumar Gupta, Devender Pathak, Shivendra Kumar, Ateet Srivastava, Avinash Kumar Mishra, Aman Patel, Harshit Prajapati
Current Traditional Medicine, 2025
Structural Insights and Biological Activities of Furan-Based Drugs in the Treatment of Human Diseases
Avinash Kumar Mishra, Kuldeep Singh, Sunam Saha, Harsh Bhardwaj, Jeetendra Kumar Gupta, Kamal Shah, Shivendra Kumar, Divya Jain, Hritik Verma
Combinatorial Chemistry and High Throughput Screening, 2025
Precision Medicine in Neurodegenerative Diseases: Genomic Approaches to Target Amyloid-β, Tau, and Alpha-Synuclein Pathways
Zaid Waqar, Pranshul Sethi, Divya Jain, Kuldeep Singh, Omar Awad Alsaidan, Sami I. Alzarea, Jeetendra Kumar Gupta, Swati Saxena, Mukesh Chandra Sharma
Current Genomics, 2025
A comparative study of neuropharmacological properties of Tabernaemontana divaricata (Apocynaceae) leaves extracts in a Swiss albino mouse model
, Konatham Teja Kumar Reddy, Jeetendra Kumar Gupta, , Prabitha P., , M. Mubeen, , Sabeena Hussain Syed, , K. Dhunmati, , Anoop Bodapati, , Poonam Popatrao Taru, , Pavankumar Krosuri, , P. Dharani Prasad, and
European Journal of Clinical and Experimental Medicine, 2025
Biological Exploration of ((Substituted-Phenyl-1H-Pyrazol-4-yl) Methylene) Aniline Derivatives as Potential DPP-IV Inhibitors: ADMET Screening, Molecular Docking, and Dynamics Simulations
Chemical Methodologies, 2025
Monoterpenoid synergy: a new frontier in biological applications
Md. Zamshed Alam Begh, Jishan Khan, Md Al Amin, Sherouk Hussein Sweilam, G. Dharmamoorthy, Jeetendra Kumar Gupta, J. Sangeetha, R. Lokeshvar, Mohamed H. Nafady, Irfan Ahmad, Mohammed Ali Alshehri, Talha Bin Emran
Naunyn Schmiedeberg S Archives of Pharmacology, 2025
Signaling Pathways Concerning Mitochondrial Dysfunction: Implications in Neurodegeneration and Possible Molecular Targets
Yati Sharma, Jeetendra Kumar Gupta, M. Arockia Babu, Sumitra Singh, Rakesh K. Sindhu
Journal of Molecular Neuroscience, 2024
Unveiling the therapeutic potential of traditional Chinese medicine Rhizome Coptidis: A comprehensive review
Kuldeep Singh, Jeetendra Kumar Gupta, Divya Jain, Alka N Chaudhary, Shivendra Kumar, Mukesh Chandra Sharma, Bhupendra Singh
Pharmacological Research Modern Chinese Medicine, 2024
The Therapeutic Management of Chemical and Herbal Medications on Uric Acid Levels and Gout: Modern and Traditional Wisdom
Zhijian Lin, Jeetendra Kumar Gupta, Mohsin Maqbool, Krishan Kumar, Ayushi Sharma, Nitin Wahi
Pharmaceuticals, 2024
Recent advances in the synthesis of antidepressant derivatives: pharmacologic insights for mood disorders
Jeetendra Kumar Gupta, Kuldeep Singh, Alok Bhatt, Prateek Porwal, Rekha Rani, Anubhav Dubey, Divya Jain, Sachchida Nand Rai
3 Biotech, 2024
Unique Characteristics of Adipocytes in Metabolic Health: Insights and Implications
Jeetendra Kumar Gupta, Yati Sharma, Nitin Wahi, Krishan Kumar
Acta Biologica Slovenica, 2024
Emerging pharmacological approaches for Huntington's disease
Kuldeep Singh, Divya Jain, Pranshul Sethi, Jeetendra Kumar Gupta, Arpan Kumar Tripathi, Shivendra Kumar, Satyajit D. Sarker, Lutfun Nahar, Ajay Guru
European Journal of Pharmacology, 2024
Bioanalytical Method Development and Validation for the Estimation of Hydroxyproline in Urine Samples of Osteoarthritic Patients Using LC–MS/MS Technique
Anil Kumar Tallam, Konatham Teja Kumar Reddy, Uttam Prasad Panigrahy, Alapati Sahithi, S. Prema, Jeetendra Kumar Gupta, D. Jeslin, Aparajita Neogi, Vinod Thomas, R. S. Chandan
SN Computer Science, 2024
Efficacy and safety of stem cell therapy in patients with dilated cardiomyopathy: an umbrella review of systematic reviews
Jun Ran, Arkadiusz Dziedzic, Israa Habeeb Naser, Ramaiah Itumalla, Jeetendra Kumar Gupta, Sarvesh Rustagi, Prakasini Satapathy, Mahalaqua Nazli Khatib, Shilpa Gaidhane, Quazi Syed Zahiruddin, Abhay M Gaidhane, Ranjit Sah
International Journal of Surgery London England, 2024
Alkaloid-based modulators of the PI3K/Akt/mTOR pathway for cancer therapy: Understandings from pharmacological point of view
Fatima Zohra Mokhfi, Md Al Amin, Mehrukh Zehravi, Sherouk Hussein Sweilam, Uppuluri Varuna Naga Venkata Arjun, Jeetendra Kumar Gupta, Bhaskar Vallamkonda, Anitha Balakrishnan, Manjula Challa, Jyoti Singh, P. Dharani Prasad, Syed Salman Ali, Irfan Ahmad, Koula Doukani, Talha Bin Emran
Chemico Biological Interactions, 2024
A comprehensive review of cellular stress response pathway system of Rhizoma coptidis
Alok Batt, Kuldeep Singh, Jeetendra Kumar Gupta, Dilip Kumar Chanchal, Kamlesh Kumar, Anubhav Dubey, Shivendra Kumar, Divya Jain
Pharmacological Research Modern Chinese Medicine, 2024
Identifying Potent Breast Cancer Inhibitors Against ERα Target Using Pharmacophore Model, 3D-QSAR and MD Studies
Kalirajan Rajagopal, Pandiselvi Arumugasamy, Kannan Raman, Srikanth Jupudi, Gowramma Byran, Jeetendra Kumar Gupta, S. Prema, Rani S. Kankate, Lamyae Elansari, Nazmul Hossain, Md. Abul Hassan, Safia Obaidur Rab, Mohammed Ali Alshehri, Talha Bin Emran
Chemistryselect, 2024
Advances in gene therapy approaches targeting neuro-inflammation in neurodegenerative diseases
Kuldeep Singh, Pranshul Sethi, Samaresh Datta, Jitendra Singh Chaudhary, Sunil Kumar, Divya Jain, Jeetendra Kumar Gupta, Shivendra Kumar, Ajay Guru, Siva Prasad Panda
Ageing Research Reviews, 2024
Bioactive Extracts from the Fruit Rind of Limonia acidissima L. Exhibit Neuro-Modulatory Properties in a Thiopental-Sodium Sleep Model in Swiss Albino Mice: Implications for Neuro-Pharmacological Interventions
Fahadul Islam, Md. A K, Balaji Pandiyan, Jeetendra Kumar Gupta, Ronald Darwin, et al.
Journal of Biological Regulators and Homeostatic Agents, 2024
Exploring the ancient wisdom and modern relevance of Chinese medicine: A comprehensive review
Kuldeep Singh, Jeetendra Kumar Gupta, Divya Jain, Shivendra Kumar, Talever Singh, Sunam Saha
Pharmacological Research Modern Chinese Medicine, 2024
Association of air pollution with risk and severity of obstructive sleep apnea: A systematic review and meta-analysis
Tahani Alrahbeni, Jeetendra Kumar Gupta, Anas Alkhouri, Ladi Alik Kumar, Ahmed Mahal, Khalid Al-Mugheed, Prakasini Satapathy, Neelima Kukreti, Mahalaqua Nazli Khatib, Shilpa Gaidhane, Abhay M. Gaidhane, Sarvesh Rustagi, Dibyalochan Mohanty, Bijaya Kumar Padhi
Neurotoxicology, 2024
Protective effect of stigmasterol enriched extract of Bacopa monnieri in ovalbumin (OVA)-induced asthma: An experimental and network pharmacology studies
Shiv Narayan, Sudeep Kumar Mandal, Jeetendra Kumar Gupta
Natural Resources for Human Health, 2024
Hybrids of imidazole with indoline derivatives: Microwave assisted synthesis, molecular docking studies, possible biological activities
Shaheen Sultana, Pandian P, Jeetendra Kumar Gupta, Rajkamal B, Praveen Barmavatu, Dibyalochan Mohanty
Journal of the Indian Chemical Society, 2024
The emergence and implications of SARS-CoV-2 omicron subvariant BA.2.86 on global health
Prakasini Satapathy, Pawan Kumar, Jeetendra K. Gupta, Ali A. Rabaan, Nawal A. Al Kaabi, Dibyalochan Mohanty, Pathakala Naveen, Mahalaqua Nazli Khatib, Shilpa Gaidhane, Quazi Syed Zahiruddin, Ahmad Neyazi
International Journal of Surgery London England, 2024
Exploring Chinese herbal medicine for the treatment of inflammatory bowel disease: A comprehensive overview
Jeetendra Kumar Gupta, Aniruddh Pratap Singh, Yati Sharma
Pharmacological Research Modern Chinese Medicine, 2024
The escalation of NiV infection: Epidemiological trends, clinical manifestations, and global implications
Prakasini Satapathy, Shilpa Gaidhane, Quazi Syed Zahiruddin, Jeetendra Kumar Gupta, Vinay Suresh, Sarvesh Rustagi, Ranjan K. Mohapatra, Ranjit Sah
Travel Medicine and Infectious Disease, 2024
Osseous implications of proton pump inhibitor therapy: An umbrella review
Abdullah S. Alanazi, Hadiah Almutairi, Jeetendra Kumar Gupta, Dibyalochan Mohanty, Deepankar Rath, Ali A. AlOdan, Ahmed Mahal, Mahalaqua Nazli Khatib, Shilpa Gaidhane, Quazi Syed Zahiruddin, Sarvesh Rustagi, Prakasini Satapathy, Hashem Abu Serhan
Bone Reports, 2024
Anti-amnesic and Neuroprotective Potential of Genistein Against Alzheimer’s Disease
Niraj Kumar Singh, Neeraj Verma, Jeetendra Kumar Gupta, Jyoti Raghav
Revista Brasileira De Farmacognosia, 2024
The Role of Aldose Reductase in Polyol Pathway: An Emerging Pharmacological Target in Diabetic Complications and Associated Morbidities
Jeetendra Kumar Gupta
Current Pharmaceutical Biotechnology, 2024
Enlightening Pharmacological Mechanisms of Cannabidiol in Epilepsy: A Comprehensive Review on their Neuroprotective Potential
Aman Shrivastava, Jeetendra Kumar Gupta
Indian Journal of Pharmaceutical Education and Research, 2024
Pharmacological Potential of Bioactive Peptides for the Treatment of Diseases Associated with Alzheimer's and Brain Disorders
Jeetendra Kumar Gupta, Kuldeep Singh
Current Molecular Medicine, 2024
Unveiling the Molecular Mechanism of Diosmetin and its Impact on Multifaceted Cellular Signaling Pathways
Krishna Kumar Varshney, Jeetendra Kumar Gupta, Rajnish Srivastava
Protein and Peptide Letters, 2024
Formulation, Optimization and Characterization of PLGA-Chitosan Nanoparticles Containing Vinorelbine Ditartrate
Varsha Bandil, Jeetendra Kumar Gupta, Manoj Kumar Goyal
Indian Journal of Pharmaceutical Education and Research, 2024
Neuroprotective Potential of Orientin with Antiepileptic Drugs against Pentylenetetrazole-induced Kindling Model and Evaluation of Behavioral Assessment in Mice
Aman Shrivastava, Jeetendra K. Gupta, Kamal Shah
Current Enzyme Inhibition, 2024
Investigating In silico and In vitro Therapeutic Potential of Diosmetin as the Anti-Parkinson Agent
Krishna Kumar Varshney, Jeetendra Kumar Gupta, Rajnish Srivastava
Protein and Peptide Letters, 2024
The Pharmacological Potential of Resveratrol in Reducing Soft Tissue Damage in Osteoarthritis Patients
Kuldeep Singh, Jeetendra Kumar Gupta, Shivendra Kumar
Current Rheumatology Reviews, 2024
Screening and Analysis of Skin Cancer Treatment Using Biocomponents of Plants Using Backpropagation Neural Networks: A Comprehensive Review
Urvashi Soni, Jeetendra Kumar Gupta, Kuldeep Singh, Girdhar Khandelwal
Current Cancer Therapy Reviews, 2024
The Potential Role of Soybean Bioactive Peptides in the Prevention and Cure of Carcinoma and Cardiovascular Disorder
Kuldeep Singh, Jeetendra Kumar Gupta, Shivendra Kumar, Talever Singh
Current Bioactive Compounds, 2024
A Review of the Common Neurodegenerative Disorders: Current Therapeutic Approaches and the Potential Role of Bioactive Peptides
Kuldeep Singh, Jeetendra Kumar Gupta, Shivendra Kumar, Urvashi Soni
Current Protein and Peptide Science, 2024
Hepatic Ischemia-reperfusion Injury: Protective Approaches and Treatment
Kuldeep Singh, Jeetendra Kumar Gupta, Shivendra Kumar, Anurag, Soumyadip Mukherjee, Aman Patel
Current Molecular Pharmacology, 2024
Suitability of Hybrid Quantum Dots as Payload for Plants
Uma Sankar Gorla, Jeetendra Kumar Gupta, Prasanthi Samathoti, Alapati Sahithi, Mohana Vamsi Nuli, Vakkalagadda Ravi Kumar, Rasapelly Ramesh Kumar
Engineering Materials, 2024
Harnessing the Pyrazine Moiety for Potent Anti-inflammatory Activity: A Comprehensive Review
Kuldeep Singh, Jeetendra Kumar Gupta, Kamal Shah, Sunam Saha, Marianesan Arockia Babu, Shivendra Kumar, Mohit Agrawal
Current Organic Chemistry, 2024
Life Cycle Assessment of Quantum Dots and Its Composites
M. Jeevitha, Jeetendra Kumar Gupta, Alapati Sahithi, Anil Kumar Tallam, Venkata Lakshamana Sagar Dantinapalli, Selvaraja Elumalai, Jeslin Devadhas, Yallamalli Indira Muzib
Engineering Materials, 2024
Visible Light Photocatalytic Degradation of Environmental Pollutants Using Zn-Doped NiO Nanoparticles
S. Minisha, J. Johnson, Saikh Mohammad, Jeetendra Kumar Gupta, Sikandar Aftab, Asma A. Alothman, Wen-Cheng Lai
Water Switzerland, 2024
Deciphering the Genetic Landscape: Exploring the Relationship Between HLA-DQA1, HLA-DQB1, and HLA-DRB1 Genes in Diabetes Mellitus
Kuldeep Singh, Jeetendra Kumar Gupta, Dilip Kumar Chanchal, Shahbaz Khan, Arti Varma, Kumari Shanno, Shivendra Kumar, Shamim
Current Pharmacogenomics and Personalized Medicine, 2024
Synthesis Strategies of Doped QDs
Konatham Teja Kumar Reddy, A. Venkata Badarinath, Jeetendra Kumar Gupta, Yeluguri Manikanta, Nagam Santhi Priya, G. Vamseekrishna, Jimmy Alex, Alapati Sahithi
Engineering Materials, 2024
Cytotoxicity of Quantum Dots Based Nanocomposites
Konatham Teja Kumar Reddy, N. Venkatesan, M. V. Saranya, Jeevanandham Somasundaram, Jeetendra Kumar Gupta, Nagam Santhi Priya, Prakash Srichand Sukhramani, Anasuya Patil
Engineering Materials, 2024
Discovery and History of Quantum Dots
Konatham Teja Kumar Reddy, B. Madhavi Latha, Jeetendra Kumar Gupta, A. Chaitanya, P. Srinivasa Babu, Vamseekrishna. G., Yeluguri Manikanta, Alapati Sahithi
Engineering Materials, 2024
Recent Advances in the Synthesis of Antioxidant Derivatives: Pharmacological Insights for Neurological Disorders
Kuldeep Singh, Jeetendra Kumar Gupta, Pranshul Sethi, Sojomon Mathew, Alok Bhatt, Mukesh Chandra Sharma, Sunam Saha, Shamim, Shivendra Kumar
Current Topics in Medicinal Chemistry, 2024
Impact of Bioactive Compounds in the Management of Various Inflammatory Diseases
Ritchu Babbar, Arpanpreet Kaur, Vanya, Rashmi Arora, Jeetendra Kumar Gupta, Pranay Wal, Arpan Kumar Tripathi, Akshada Amit Koparde, Pradeep Goyal, Seema Ramniwas, Monica Gulati, Tapan Behl
Current Pharmaceutical Design, 2024
Design and Synthesis of Pyrazole-Substituted 9-Anilinoacridine Derivatives and Evaluation against Breast Cancer
Dhinesh Kumar Murugesan, Kalirajan Rajagopal, Arumugam R. Vijayakumar, Gothandam Sundararajan, Kannan Raman, et al.
Journal of Biological Regulators and Homeostatic Agents, 2024
Bioactive molecules from terrestrial and seafood resources in hypertension treatment: focus on molecular mechanisms and targeted therapies
Md. Rezaul Islam, Puja Sutro Dhar, Shopnil Akash, Sabeena Hussain Syed, Jeetendra Kumar Gupta, Kumaraswamy Gandla, Muniya Akter, Abdur Rauf, Hassan A. Hemeg, Yasir Anwar, Bassam Oudh Aljohny, Polrat Wilairatana
Natural Products and Bioprospecting, 2023
Recent perspective on the potential role of phytocompounds in the prevention of gastric cancer
Md. Rezaul Islam, Abdur Rauf, Shopnil Akash, Ajoy Kumer, Md Sadique Hussain, Smrity Akter, Jeetendra Kumar Gupta, L.H. Thameemul Ansari, Mir Md. Mahfoj Islam Raj, Talha Bin Emran, Abdullah S.M. Aljohani, Waleed Al Abdulmonem, Rekha Thiruvengadam, Muthu Thiruvengadam
Process Biochemistry, 2023
Research Progress of Indole Alkaloids: Targeting MAP Kinase Signaling Pathways in Cancer Treatment
Md. Al Amin, Talha Bin Emran, Jishan Khan, Mehrukh Zehravi, Indu Sharma, Anasuya Patil, Jeetendra Kumar Gupta, D. Jeslin, Karthickeyan Krishnan, Rajib Das, Firzan Nainu, Irfan Ahmad, Polrat Wilairatana
Cancers, 2023
Synthesis and Characterizations of Fe-Doped NiO Nanoparticles and Their Potential Photocatalytic Dye Degradation Activities
S. Minisha, J. Johnson, Saikh Mohammad Wabaidur, Jeetendra Kumar Gupta, Sikandar Aftab, Masoom Raza Siddiqui, Wen-Cheng Lai
Sustainability Switzerland, 2023
Pharmacological and therapeutic potential of Hordeum vulgare
Kuldeep Singh, Jeetendra Kumar Gupta, Shivendra Kumar, Himansu Chopra, Sunil Kumar, Dilip Kumar Chanchal, Talever Singh, Ramkumar Chaudhary, Akash Garg, Sunam Saha, Devender Pathak, Avinash Kumar Mishra, Rutvi Agrawal, Urvashi Soni, Brajnandan Dubey
Pharmacological Research Modern Chinese Medicine, 2023
UV-Light-Driven Photocatalytic Dye Degradation and Antibacterial Potentials of Biosynthesized SiO2 Nanoparticles
Parvathiraja Chelliah, Jeetendra Kumar Gupta, Saikh Mohammad Wabaidur, Masoom Raza Siddiqui, Siaw Foon Lee, Wen-Cheng Lai
Water Switzerland, 2023
Development of Soft Luliconazole Invasomes Gel for Effective Transdermal Delivery: Optimization to In-Vivo Antifungal Activity
Sunitha Kumari, Omar Awad Alsaidan, Dibyalochan Mohanty, Ameeduzzafar Zafar, Swagatika Das, Jeetendra Kumar Gupta, Mohammad Khalid
Gels, 2023
Development of Atomoxetine-Loaded NLC In Situ Gel for Nose-to-Brain Delivery: Optimization, In Vitro, and Preclinical Evaluation
Dibyalochan Mohanty, Omar Awad Alsaidan, Ameeduzzafar Zafar, Trishala Dodle, Jeetendra Kumar Gupta, Mohd Yasir, Anshuman Mohanty, Mohammad Khalid
Pharmaceutics, 2023
Antibacterial and Photocatalytic Dye Degradation Activities of Green Synthesized NiSe Nanoparticles from Hibiscus rosa-sinensis Leaf Extract
Lakshmi Velayutham, C. Parvathiraja, Dhivya Christo Anitha, K. Mahalakshmi, Mary Jenila, Jeetendra Kumar Gupta, Saikh Mohammad Wabaidur, Masoom Raza Siddiqui, Sikandar Aftab, Wen-Cheng Lai
Water Switzerland, 2023
Emergence of Synthetic Cannabinoids: Pharmacological insights and adverse effects
Jeetendra Kumar Gupta
Research Journal of Chemistry and Environment, 2023
The Use of Enzyme Inhibitors in Drug Discovery: Current Strategies and Future Prospects
Kuldeep Singh, Jeetendra Kumar Gupta, Devendra Pathak, Shivendra Kumar
Current Enzyme Inhibition, 2023
Appraisal, recent advancement, and impacts of nanomedicine in cardiac asthma
Jeetendra Kumar Gupta, Abdul Razak Mohamed Sikkander, Faizan ul Haque Nagrami, Krishan Kumar, Nitin Wahi
Journal of Medical Pharmaceutical and Allied Sciences, 2023
Implications of Glutathione-S-transferases in Mitogen-activated protein kinase pathway: Risk associated with anticancer drug resistance
Jeetendra Kumar Gupta
Research Journal of Chemistry and Environment, 2022
Neuroprotective Efficacy of Quercetin with Lamotrigine and Gabapentin Against Pentylenetetrazole-induced Kindling and Associated Behavioral Comorbidities in Mice
Aman Shrivastava, Jeetendra Kumar Gupta, Manoj Kumar Goyal
Indian Journal of Pharmaceutical Education and Research, 2022
Advantage of Adrenomedullin as remedial contrivance for left ventricular remodeling after acute myocardial infarction
Jeetendra Kumar Gupta, Krishanveer Singh, Kuldeep Singh, Shivendra Kumar
Research Journal of Chemistry and Environment, 2022
Therapeutic Approaches of Nanotechnology for Epileptic Seizures: A Comprehensive Review of Current Knowledge
Aman Shrivastava, Jeetendra K Gupta, Manoj K Goyal
Indian Journal of Pharmaceutical Education and Research, 2022
Potential Efficacy of Ocimum sanctum Hydro-Alcoholic Leaf Extract as an Adjuvant Role with Phenobarbital: Acute Models of Epilepsy on Mice
Aman Shrivastava, JeetendraKumar Gupta, ManojKumar Goyal
International Journal of Nutrition Pharmacology Neurological Diseases, 2022
Angiotensin-(1-7): A novel therapeutic target for preventing cardiovascular disease
Jeetendra Kumar Gupta, Krishanveer Singh, Kuldeep Singh
Research Journal of Biotechnology, 2022
Role of atrial natriuretic peptide in abrogated cardio protective effect of ischemic postconditioning in diabetic rat heart
Biomedical and Biotechnology Research Journal, 2022
Development, In-Vitro Characterization and Preclinical Evaluation of Esomeprazole-Encapsulated Proniosomal Formulation for the Enhancement of Anti-Ulcer Activity
Dibyalochan Mohanty, Ameeduzzafar Zafar, Mohammed Jafar, Atul Kumar Upadhyay, Mohammad Akiful Haque, Jeetendra Kumar Gupta, Vasudha Bakshi, Mohammed M. Ghoneim, Sultan Alshehri, Mohammed Asadullah Jahangir, Mohammed Javed Ansari
Molecules, 2022
Preparation, biological evaluation and radiolabeling of [99mTc]-technetium tricarbonyl procainamide as a tracer for heart imaging in mice
M. H. Sanad, Fawzy A. Marzook, Ayman B. Farag, Sudip Kumar Mandal, Syed F. A. Rizvi, Jeetendra Kumar Gupta
Radiochimica Acta, 2022
Safety and sagacious use of remdesivir: Paramount focus on contemporary perspectives
JeetendraKumar Gupta
Biomedical and Biotechnology Research Journal, 2022
Common respiratory viruses and collapsing health: Prodigious focus on ambient air pollution
JeetendraKumar Gupta
Biomedical and Biotechnology Research Journal, 2022
Flavonoids and antiepileptic drugs: A comprehensive review on their neuroprotective potentials
Journal of Medical Pharmaceutical and Allied Sciences, 2022
Role of ACE and ACE-2 in abrogated cardioprotective effect of ischemic preconditioning in ovariectomized rat heart
Vimal Kumar, Ahsas Goyal, Jeetendra Kumar Gupta
Brazilian Journal of Pharmaceutical Sciences, 2022
Phytoestrogens as Potential Antiandrogenic Agents Against Prostate Cancer: An In Silico Analysis
Neetu Agrawal, Somdutt Mujwar, Ahsas Goyal, Jeetendra Kumar Gupta
Letters in Drug Design and Discovery, 2022
Role of caveolin-eNOS platform and mitochondrial ATP-sensitive potassium channel in abrogated cardioprotective effect of ischemic preconditioning in postmenopausal women
Ahsas Goyal, Neetu Agrawal, Ankit Jain, Jeetendra Kumar Gupta, Debapriya Garabadu
Brazilian Journal of Pharmaceutical Sciences, 2022
Ceiling effect of Postconditioning and Atrial Natriuretic Peptide in Cardioprotection against Ischemia Reperfusion Injury in Ovariectomized rat hearts
Vishal Kumar Vishwakarma, Prabhat Kumar Upadhyay, Jeetendra Kumar Gupta, Ritesh Kumar Srivasata, Tarique Mahmood Ansari
Brazilian Journal of Pharmaceutical Sciences, 2022
Role of Atrial Natriuretic Peptide in Abrogated Cardio protective Effect of Ischemic Postconditioning in Diabetic Rat Heart
Latin American Journal of Pharmacy, 2022
Ameliorative Effect of Acetyl L-carnitine in Alzheimer's Disease via Down-regulating of Homocysteine Levels in Hyperhomocysteinemia Induced Cognitive Deficit in Mouse Model
Nisha Verma, Jeetendra Kumar Gupta, Krishna Kumar Varshney, Rajnish Srivastava
Drug Metabolism Letters, 2021
Paroxysm of eclampsia in pregnant women: Pharmacology of intervening drugs
Research Journal of Biotechnology, 2021
Safety and toxicological profile of contemporary analeptics: Prodigious focus on doxapram and almitrine
Jeetendra Kumar Gupta
Research Journal of Pharmacy and Technology, 2021
Phytoestrogens are emerging medicine in prevention and management of cognitive deficits in postmenopausal women
Ahsas Goyal, Jeetendra Kumar Gupta, Debapriya Garabadu
Research Journal of Pharmacy and Technology, 2021
Vinorelbine: A potential breakthrough in cancer therapy
Varsha Bandil, Jeetendra Kumar Gupta, Manoj Goyal
Research Journal of Pharmacy and Technology, 2021
Docking based screening of curcumin derivatives: A novel approach in the inhibition of tubercular DHFR
Somdutt Mujwar, Kamal Shah, Jeetendra Kumar Gupta, Alekh Gour
International Journal of Computational Biology and Drug Design, 2021
Inadmissible planktons in potable water: a potential risk for human health
Jeetendra Kumar Gupta, Kamal Shah, Pradeep Mishra
Current Science, 2020
An insight into the sars-cov-2: Use of zinc ionophores - a blockbuster approach
Research Journal of Chemistry and Environment, 2020
Computational design and biological depiction of novel naproxen derivative
Kamal Shah, Somdutt Mujwar, Gaurav Krishna, Jeetendra K. Gupta
Assay and Drug Development Technologies, 2020
Bipolar disorder: A major setback in substance abuse
Indian Journal of Forensic Medicine and Toxicology, 2020
A contemporary study on recommending outline of antiepileptic drugs
International Journal of Pharmaceutical Research, 2020
Epileptogenic drugs and seizures: A comprehensive review of current knowledge
International Journal of Pharmaceutical Research, 2020
Flibanserin: A miracle drug in management of hypoactive sexual desire disorder in female
Indian Journal of Forensic Medicine and Toxicology, 2020
New facile technique for estimation of piroxicam in bulk drug
International Journal of Pharmaceutical Research, 2020
Drug Repurposing Approach for Developing Novel Therapy against Mupirocin-Resistant Staphylococcus aureus
Somdutt Mujwar, Rohitas Deshmukh, Ranjit K. Harwansh, Jeetendra Kumar Gupta, Alekh Gour
Assay and Drug Development Technologies, 2019
Role of testosterone in swimming exercise-induced analgesia in rats
Dheeraj Kumar Sharma, Niraj Kumar Singh, Ahsas Goyal, Jeetendra Kumar Gupta, Harlokesh Narayan Yadav
Indian Journal of Pharmaceutical Education and Research, 2019
A novel approach in the management of hyperhomocysteinemia
Shaiba Sana Qureshi, Jeetendra Kumar Gupta, Ahsas Goyal, Harlokesh Narayan Yadav
Medical Hypotheses, 2019
Molecular Docking and in Silico Cogitation Validate Mefenamic Acid Prodrugs as Human Cyclooxygenase-2 Inhibitor
Kamal Shah, Somdutt Mujwar, Jeetendra Kumar Gupta, Sushant K. Shrivastava, Pradeep Mishra
Assay and Drug Development Technologies, 2019
Involvement of atrial natriuretic peptide in abrogated cardioprotective effect of ischemic preconditioning in ovariectomized rat heart
VK Vishwakarma, A Goyal, JK Gupta, PK Upadhyay, HN Yadav
Human and Experimental Toxicology, 2018
Environmental pollutants and aggressive climatic conditions: Combination scaffolds of brain stroke
Jeetendra Kumar Gupta, Kamal Shah, Pradeep Mishra
Current Science, 2018
Prodrugs of NSAIDs: A review
Kamal Shah, Jeetendra K. Gupta, Nagendra S. Chauhan, Neeraj Upmanyu, Sushant K. Shrivastava, Pradeep Mishra
Open Medicinal Chemistry Journal, 2017
Pharmacological screening of some newly synthesized triazoles for H1 receptor antagonist activity
Jeetendra Kumar Gupta, Pradeep Mishra
Medicinal Chemistry Research, 2017
Antimicrobial screening of some newly synthesized triazoles
Jeetendra Gupta, Pradeep Mishra
Journal of Pure and Applied Microbiology, 2017
Pharmacological importance of Cucumis melo L.: An overview
Vishal Kumar Vishwakarma, Jeetendra Kumar Gupta, Prabhat Kumar Upadhyay
Asian Journal of Pharmaceutical and Clinical Research, 2017
Antimicrobial and anthelmintic activities of some newly synthesized triazoles
Jeetendra Kumar Gupta, Pradeep Mishra
Asian Journal of Pharmaceutical and Clinical Research, 2017
Role of cardiac renin angiotensin system in ischemia reperfusion injury and preconditioning of heart
Vimal Agrawal, Jeetendra Kumar Gupta, Shaiba Sana Qureshi, Vishal Kumar Vishwakarma
Indian Heart Journal, 2016
Role of atrial natriuretic peptide in various conditions
International Journal of Pharma and Bio Sciences, 2016
Improvement in renal function of hyperhomocysteinemic rats by co-enzyme Q10
International Journal of Pharmaceutical Sciences Review and Research, 2016
Role of atrial natriuretic peptide in ischemic preconditioning-induced cardioprotection in the diabetic rat heart
Kali Charan, Ahsas Goyal, Jeetendra Kumar Gupta, Harlokesh Narayan Yadav
Journal of Surgical Research, 2016
Prevalence and risk factor of polycystic ovarian syndrome
Asian Journal of Pharmaceutical and Clinical Research, 2016
Synthesis of new 1,2,4-triazoles as anti-inflammatory and anti-nociceptive agents
N. Upmanyu, J. K. Gupta, K. Shah, P. Mishra
Pharmaceutical Chemistry Journal, 2011
Anti-inflammatory and antinociceptive evaluation of newly synthesized 4-(substituted ethanoyl) amino-3-mercapto-5-(4-methoxy) phenyl-1,2,4-triazoles
Neeraj Upmanyu, Jeetendra Kumar Gupta, Kamal Shah, Pradeep Mishra
Journal of Pharmacy and Bioallied Sciences, 2011
Blood glucose lowering potential of Stem Bark of Berberis aristata Dc in Alloxan-induced diabetic rats
Iranian Journal of Pharmacology and Therapeutics, 2010
Evaluation of antiulcer activity of Leucas lavandulifolia on mucosal lesion in rat
Asian Journal of Pharmaceutical and Clinical Research, 2010
Patients with disturbed biorhythm and secondary beneficial effect of melatonin
International Journal of Pharmacy and Pharmaceutical Sciences, 2009
Evaluation of antidiabetic and in vitro antioxidant activity of Leucas lavandulifolia Sm. (Labiatae)
Indian Drugs, 2008

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