Anthropometric and Biochemical Correlates of Sarcopenia in Type 2 Diabetes Mellitus Patients Aged Over 40 Years: An Observational Study Sanjay T. Thorat, Virendra C. Patil Journal of Diabetology, 2026 Background: Sarcopenia, the progressive loss of muscle mass and strength, is a growing complication of type 2 diabetes mellitus (T2DM). However, its link with glycemic control, particularly in younger patients, remains unclear. This study aimed to determine the prevalence of sarcopenia in T2DM and examine its association with glycated hemoglobin (HbA1c). Materials and Methods: This cross-sectional study included 157 T2DM patients aged >40 years. Sarcopenia was assessed using the Asian Working Group for Sarcopenia criteria. The appendicular skeletal muscle mass, handgrip strength, Five-Time Sit-to-Stand Test, anthropometric, and laboratory parameters were analyzed. The statistical analyses included t -tests, chi-square tests, and receiver operating characteristic analysis. Results: Sarcopenic patients had lower body mass index ( P < 0.001), waist circumference ( P < 0.001), and low handgrip strength ( P = 0.012) and reduced calf circumference ( P < 0.001). HbA1c showed no association ( P = 0.209, area under the curve = 0.453) with sarcopenia. The serum creatinine and blood urea levels were positively correlated with appendicular skeletal muscle mass ( r = 0.204, P < 0.05) and skeletal muscle index ( r = 0.182, P < 0.05), whereas hand grip strength was correlated positively with blood urea ( r = 0.161, P < 0.05). Estimated glomerular filtration rate (eGFR) was significantly lower in females with longer diabetes duration (≥5 years) compared with those with duration <5 years, and a trend ( P = 0.06) of lower eGFR was noted in females with higher HbA1c (≥8). Conclusion: The study revealed that neither glycemic control nor renal function markers are linked to sarcopenia in the relatively younger diabetic cohort (40–60 years). However, the handgrip strength and calf circumference served as good indicators of sarcopenia, suggesting the clinical utility of simple bed-site measures.
The Impact of Co-Curricular Activities on University Students with Disabilities International Journal of Special Education, 2026
Introduction to AI in Chronic Disease Management Overview of AI Technologies and Their Transformative Impact on Chronic Disease Care V. C. Patil, G. M. Vaidya Artificial Intelligence and Machine Learning in Neurology 2 Volume Set, 2026 Chronic diseases like diabetes, hypertension, and cardiovascular disorders are straining health systems around the world. They claim countless lives and drive up spending more than any single outbreak ever could. Yet, in the past few years, artificial intelligence has begun to reshape how these conditions are managed, turning once-static care paths into dynamic journeys. Predictive analytics, personalized therapy, and continuous monitoring now stand at the forefront of this shift. Three AI subfields—powerful computer vision, flexible machine learning, and intuitive natural language processing—drive the change. Hospitals and clinics are steadily embedding these tools into daily practice in hopes of bending the chronic-disease curve. Machine learning models sift through mountains of clinical data, uncover hidden trends, and project future risk. By surfacing subtle signals that human eyes might miss, they empower doctors to act sooner and curb complications. Crafting truly tailored care is the next leap. When algorithms pull from electronic records, wearables, and even genomic profiles, they can recommend the right drug dose or lifestyle tweak for a single patient. That precision boosts adherence, cuts side effects, and, ultimately, improves quality of life.
Non-Alcoholic Fatty Liver Disease (NAFLD) in Subjects with Metabolic Syndrome Virendra C. Patil, Aniket Pathade, Ashish Bhagat, Harsha Virendra Patil, Shivamsh R. Kasireddy Journal of Datta Meghe Institute of Medical Sciences University, 2026 Background: Metabolic syndrome (MetS) is recognized to have a strong association with nonalcoholic fatty liver disease (NAFLD). NAFLD is recognized as a major cause of liver-related mortality and morbidity. Aims and Objectives: This study aims to study NAFLD in subjects with MetS and to compare them with subjects without MetS. Materials and Methods: This was a hospital-based cross-sectional observational study done on subjects with and without MetS in a tertiary care hospital over a period of 6 months from October 2020 to March 2021. Enrolled subjects underwent ultrasonography, point shear wave elastography (pSWE), fasting blood sugar (F-BSL), postprandial blood sugar, HbA1c, fasting lipid profile, and LFTs. Appropriate statistical tests were applied for analysis and P < 0.05 was considered statistically significant. Results: The mean age was 50.98 (standard deviation [SD] ±14.80) in those without MetS and 50.88 (SD ± 14.46) with MetS. Mean pSWE elasticity was 3.08 kPa (SD ± 1.77) in those without MetS and 6.00 kPa (SD ± 3.86) with MetS. Mean waist circumference was 79.34 cm (SD ± 12.41) in those without MetS and 103.22 cm (SD ± 9.88) with MetS. A substantial association was noted in the occurrence of fibrosis with the presence of MetS and its components ( P < 0.0001). Conclusion: The presence of NAFLD by shear wave elastography was significantly higher in subjects with MetS than in subjects without. It is suggested that eligible subjects with MetS should be screened for the presence of NAFLD to halt the disease progress by early intervention.
Clinical Profile, Laboratory Profile, and Outcome of Organophosphorus Poisoning at Tertiary Care Hospital Virendra Chandrashekhar Patil, Shital Telrandhe, Laxmikant Bharat Umate, Nikhilesh Iranna Rayannavar, Harsha Virendra Patil Journal of Datta Meghe Institute of Medical Sciences University, 2026 Background: Organophosphorus (OP) is reachable pesticide which has a high morbidity. There is limited information available on acute poisoning in the study area. Aim of the Study: To study the clinical profile, laboratory profile and outcome of organophosphorus poisoning at tertiary care hospital. Materials and Methods: A total of 100 individuals with organo-phosphorus poisoning were enrolled in this study and were categorized (mild, moderate, and severe poisoning groups) based on peradeniya organophosphorus poisoning (POP) score. Their serum cholinesterase (SChE) levels at the time of admission were sent and categorized into three groups. The POP score, SChE levels were analyzed to find their association with mortality, ventilator support, and duration of hospital stay. Results: Of 100 patients with organophosphorus (OP) poisoning, a majority of 36% subjects were aged between 21 and 30 years (66% males and 34% females), with a male-to-female ratio of 1.9:1. Chlorpyriphos (59%) was the most common type of poisoning followed by dimethoate (16%). A majority (46%) had mild, 38% had moderate, and 16% had severe poisoning. The overall mortality was 14%, mortality in patients requiring ventilator was 21.5% and the case fatality rates for were high in severe poisoning (62.5%). Conclusion: A higher POP score and a significant decrease in SCh-E levels were associated with increase in the duration of hospital stay, severity of poisoning, need of ventilator, and poor outcome.
Apache-II score and Ranson criteria with modified CT severity index in predicting the severity of acute pancreatitis: A comparative study Virendra C. Patil, Dany P. John, Desai Jabbar Tissue Engineering and Regenerative Medicine Advances and Applications, 2025 Physicians treat acute pancreatitis often in emergency rooms across the globe. Finding individuals suffering from severe acute pancreatitis (SAP) and that who can be benefitted from timely critical care intervention is crucial. This chapter evaluates and compares different scores – Ranson and Apache-II score – with Modified Computed Tomography Severity Index (mCTSI) in predicting severity and outcome of patients with acute pancreatitis. In the present study population of 40 patients, out of 26 patients (65%) with complications, all of them had local complications where 11 patients (42%) had necrotizing pancreatitis and the rest 15 patients (58%) had peripancreatic fluid collection. Out of 26 patients with complications, majority of 23 patients (88%) developed systemic complications [Systemic Inflammatory Response Syndrome (SIRS)]. In the current investigation of 40 patients, 10% (25%) had an APACHE II score of 0–3, 10% (25%) had a score of 4–7, whereas 20% (50%) had shown a score of 8 or above. With a ‘P’ value of 0.001, the dissemination of the APACHE II score was significant statistically.
Efficacy of structured exercise protocol on functional capacity, HbA1c, and waist-hip ratio in post-myocardial infarction subjects with diabetes mellitus Journal of Neonatal Surgery, 2025
Efficacy of Structured Exercise Protocol on Patient-Related Outcome Measures, Blood Pressure, And Waist-Hip Ratio in Post Myocardial Infarction Subjects with Hypertension Journal of Neonatal Surgery, 2025
Screening of interstitial lung disorders with a multidisciplinary approach: A comprehensive analysis of the empirical results and future prospects Onkologia I Radioterapia, 2024
A comprehensive analysis of the use of lung ultrasonography in the diagnosis and monitoring of COVID-19 disease development Onkologia I Radioterapia, 2024
Diagnostic utility of electrocardiography and transthoracic echocardiography in the diagnosis of left ventricular hypertrophy in patients with known hypertension Iranian Heart Journal, 2021
Laboratory Parameters in Patients with Moderate and Severe COVID-19 in 2020 and 2021: A Comparative Study Journal of Krishna Institute of Medical Sciences University, 2021
A comparative study of diastolic dysfunction by echocardiography among diabetic and non-diabetic subjects Journal of Krishna Institute of Medical Sciences University, 2020
Multidrug-resistant (MDR) bacterial pathogens in ventilator-associated pneumonia at tertiary care hospital International Journal of Advanced Science and Technology, 2020
Assess the efficacy of health information on knowledge regarding post dialysis home care among caretakers of haemodialysis patients International Journal of Advanced Science and Technology, 2020
Clinical profile and outcome of H1N1 influenza infection at a tertiary care teaching hospital Journal of Krishna Institute of Medical Sciences University, 2019
Multidrug resistant acinetobacter in patient with ventilator associated pneumonia: Review article Journal of Krishna Institute of Medical Sciences University, 2019
Amoebic liver abscess in newly detected hiv infection Journal of Krishna Institute of Medical Sciences University, 2019
Echocardiographic evaluation of patients with chronic obstructive pulmonary disease and its relation with the severity of the disease Research Journal of Pharmaceutical Biological and Chemical Sciences, 2016
Acceptability, feasibility and feedback analysis of perception for objective structured practical examination as an assessment tool in undergraduate in competency based medical education Journal of Krishna Institute of Medical Sciences University, 2016
Incidence, risk factors and susceptibility profile of candida species isolated from blood of non-neutropenic medical intensive care unit patients in a tertiary care centre Journal of Krishna Institute of Medical Sciences University, 2016
Study of percutaneous coronary intervention in patient with coronary artery disease at tertiary care teaching hospital Journal of Krishna Institute of Medical Sciences University, 2015
Total anomalous pulmonary venous connection (TAPVC) with severe pulmonary hypertension Journal of Krishna Institute of Medical Sciences University, 2015
A case of multiple episodes of venous thrombosis causing deep vein thrombosis, cerebral venous sinus thrombosis and pulmonary embolism in a patient with hyperhomocysteinemia Journal of Krishna Institute of Medical Sciences University, 2015
Item analysis of medicine multiple choice questions (MCQs) for under graduate (3rd year MBBS) students Research Journal of Pharmaceutical Biological and Chemical Sciences, 2015
Clinical profile, etiology, classification and outcome of cardio-renal syndrome at tertiary care teaching hospital in Western Maharashtra, India Research Journal of Pharmaceutical Biological and Chemical Sciences, 2015
Incidence, etiology and clinical profile of newly detected Chronic kidney disease (CKD) at teaching hospital Research Journal of Pharmaceutical Biological and Chemical Sciences, 2015
Incidence, bacteriology and risk factors of surgical site infection (SSI) at tertiary care teaching hospital Research Journal of Pharmaceutical Biological and Chemical Sciences, 2015
Clinical profile and outcome of organophosphorus poisoning at tertiary care centre in western Maharashtra Indian Journal of Forensic Medicine and Toxicology, 2012
Sex-Based Differences in Biochemical Markers Across Angiographic Severity of Coronary Artery Disease: A Cross-Sectional Study A Vaidya, VC Patil Clinical & Translational Metabolism 24 (1), 8 , 2026 2026
Anthropometric and Biochemical Correlates of Sarcopenia in Type 2 Diabetes Mellitus Patients Aged Over 40 Years: An Observational Study ST Thorat, VC Patil Journal of Diabetology 17 (3), 284-291 , 2026 2026
Simulation and Virtual Reality Applications in Medical Training for Tuberculosis Diagnosis S Gonge, A Jagtap, VC Patil, SJ Navale Indian Journal of Tuberculosis , 2026 2026
Introduction to AI in Chronic Disease Management Overview of AI Technologies and Their Transformative Impact on Chronic Disease Care VC Patil, GM Vaidya Artificial Intelligence and Machine Learning in Neurology 2, 533-554 , 2026 2026
Non-Alcoholic Fatty Liver Disease (NAFLD) in Subjects with Metabolic Syndrome VC Patil, A Pathade, A Bhagat, HV Patil, SR Kasireddy Journal of Datta Meghe Institute of Medical Sciences University 21 (1), 31-36 , 2026 2026
Clinical Profile, Laboratory Profile, and Outcome of Organophosphorus Poisoning at Tertiary Care Hospital VC Patil, S Telrandhe, LB Umate, NI Rayannavar, HV Patil Journal of Datta Meghe Institute of Medical Sciences University 21 (1), 37-43 , 2026 2026
Association of sarcopenia with vascular complications in patients with type 2 diabetes mellitus ST Thorat, VC Patil International Journal of Diabetes in Developing Countries, 1-8 , 2025 2025
Apache-II score and Ranson criteria with modified CT severity index in predicting the severity of acute pancreatitis: A comparative study VC Patil, DP John, D Jabbar Tissue Engineering and Regenerative Medicine, 279-289 , 2025 2025
Role of Wearable Technology in Mental Health Monitoring and Management: Psychiatric Insights into Wearable Technology Adoption SV Kshirsagar, VC Patil Internet of Medicine for Smart Healthcare, 405-428 , 2024 2024
Evolution and Impact of Wearable Devices in Healthcare: Anatomy of Wearable Technology and its Influence on Medical Sciences MP Ambali, VC Patil Internet of Medicine for Smart Healthcare, 237-262 , 2024 2024 Citations: 1
Antibiotic Resistance Profiles of Extended-Spectrum β-Lactamase (ESBL)-and Metallo-β-Lactamase (MBL)-Producing Klebsiella pneumoniae Isolates From Diabetic Foot Ulcers … HV Patil, VC Patil, AP Patange, MA Khan Cureus 16 (8) , 2024 2024 Citations: 5
Clinical and Hematological Correlates of Hemolytic Anemia in Diabetic Foot Ulcer Patients: A Prospective Observational Study VC Patil, HV Patil, DD Patil, MA Khan Cureus 16 (8) , 2024 2024 Citations: 1
VENTILATOR-ACQUIRED PNEUMONIA: STRATEGIES FOR PREVENTION, DIAGNOSIS, AND TREATMENT. A Rokade, UT Mane, VC Patil Obstetrics & Gynaecology Forum 34 (3) , 2024 2024
NON-ALCOHOLIC FATTY LIVER DISEASE: A SILENT CONTRIBUTOR TO CARDIOVASCULAR DISEASE RISK. G Shinde, A Patange, VC Patil Obstetrics & Gynaecology Forum 34 (3) , 2024 2024
ACUTE ISCHEMIC STROKE: CLINICAL PATHWAYS AND MANAGEMENT STRATEGIES. A Bahulekar, VC Patil Obstetrics & Gynaecology Forum 34 (3) , 2024 2024
COMMUNITY-ACQUIRED VS. VENTILATORACQUIRED PNEUMONIA: A COMPARATIVE STUDY OF TREATMENT OUTCOMES. VC Patil, SS Patil, SV Kakade Obstetrics & Gynaecology Forum 34 (3) , 2024 2024
MATERNAL EDUCATION AND ITS ASSOCIATION WITH CHILDHOOD VACCINATION TIMELINESS AND COMPLETENESS. V Vhawal, A Bahulekar, VC Patil Obstetrics & Gynaecology Forum 34 (3) , 2024 2024 Citations: 1
ACUTE CORONARY SYNDROME: RISK STRATIFICATION AND MANAGEMENT IN THE CONTEXT OF CORONARY ARTERY DISEASE. PA Havle, VC Patil, RV Mohite Obstetrics & Gynaecology Forum 34 (3) , 2024 2024
THE ROLE OF LIVER TRANSPLANTATION IN THE MANAGEMENT OF CIRRHOSIS AND HEPATIC FAILURE. VC Patil, SC Patil, Y Patil Obstetrics & Gynaecology Forum 34 (3) , 2024 2024
TRENDS AND OUTCOMES OF CORONARY ANGIOGRAPHY IN ACUTE CORONARY SYNDROME: A DECADE'S PERSPECTIVE. VC Patil, A Bahulekar, RP Patange Obstetrics & Gynaecology Forum 34 (3) , 2024 2024
MOST CITED SCHOLAR PUBLICATIONS
Diastolic dysfunction in asymptomatic type 2 diabetes mellitus with normal systolic function VC Patil, KB Shah, JD Vasani, P Shetty, HV Patil Journal of cardiovascular disease research 2 (4), 213-222 , 2011 2011 Citations: 283
Central venous catheter-related bloodstream infections in the intensive care unit HV Patil, VC Patil, MN Ramteerthkar, RD Kulkarni Indian Journal of Critical Care Medicine: Peer-reviewed, Official … , 2011 2011 Citations: 125
Clinical profile and outcome of cerebral venous sinus thrombosis at tertiary care center VC Patil, K Choraria, N Desai, S Agrawal Journal of neurosciences in rural practice 5 (3), 218 , 2014 2014 Citations: 91
Incidence, bacteriology, and clinical outcome of ventilator-associated pneumonia at tertiary care hospital HV Patil, VC Patil Journal of natural science, biology, and medicine 8 (1), 46 , 2017 2017 Citations: 82
Relation of anthropometric variables to coronary artery disease risk factors VC Patil, GP Parale, PM Kulkarni, HV Patil Indian journal of endocrinology and metabolism 15 (1), 31-37 , 2011 2011 Citations: 46
Cardiac tamponade in a patient with primary hypothyroidism VC Patil, HV Patil, V Agrawal, S Patil Indian journal of endocrinology and metabolism 15 (Suppl2), S144-S146 , 2011 2011 Citations: 45
Clinical profile and outcome of envenomous snake-bite at tertiary care centre in western Maharashtra. VC Patil, HV Patil, AP Avinash Patil, VA Vaibhav Agrawal 2011 Citations: 38
Clinical profile and outcome of leptospirosis at tertiary care centre in western Maharashtra VC Patil, HV Patil, V Agrawal Journal of Academy of Medical Sciences Vol 2 (1), 31 , 2012 2012 Citations: 24
Metabolic syndrome in railway employees and its relation to lifestyle factors GP Parale, VC Patil, SP Patil, SV Sabale, CV Pethe, GS Manjunath, ... Metabolic syndrome and related disorders 6 (1), 58-63 , 2008 2008 Citations: 24
Item Analysis of Medicine Multiple Choice Questions (MCQs) for Under Graduate (3rd year MBBS) Students. VCPHV Patil Research Journal of Pharmaceutical, Biological and Chemical Sciences 6 (3 … , 2015 2015 Citations: 23
High-sensitive C-reactive protein in patients with coronary artery disease VC Patil, AB Avhad, AR Kulkarni, KA Pandere Journal of Natural Science, Biology and Medicine 11 (1), 39 , 2020 2020 Citations: 22
Successful treatment of cerebral toxoplasmosis with cotrimoxazole HV Patil, VC Patil, V Rajmane, V Raje Indian Journal of Sexually Transmitted Diseases and AIDS 32 (1), 44-46 , 2011 2011 Citations: 22
Chronic obstructive pulmonary disease: Is serum magnesium level a risk factor for its acute exacerbation? K Kshirsagar, VC Patil Caspian journal of internal medicine 12 (2), 223 , 2021 2021 Citations: 21
Study of electrolyte disturbances in dengue infected patients VG Khandelwal, VC Patil, A Botre, R Patil Intern J Contemp Med Res 6, B5-8 , 2019 2019 Citations: 18
Neurological manifestations of HIV-AIDS at a tertiary care center in western Maharashtra. PHV Patil VC Int J Med P 4 (3), 210-217 , 2014 2014 Citations: 18
Clinical manifestations and outcome of patients with human immunodeficiency virus infection at tertiary care teaching hospital VC Patil, HV Patil Indian Journal of Sexually Transmitted Diseases and AIDS 37 (1), 38-45 , 2016 2016 Citations: 17
Yield and quality parameters as influenced by seasons and genotypes in marigold (Tagetes erecta L.) V Patil, BS Kulkarni, BS Reddy, P Kerure, A Ingle Res. J. Agric. Sci 2 (2), 344-347 , 2011 2011 Citations: 17
Complicated falciparum Malaria in western Maharashtra VC Patil Tropical Parasitology 2 (1), 49-54 , 2012 2012 Citations: 15
An unusual case of Weil's syndrome with paraparesis VC Patil, HV Patil, A Sakaria, S Tryambake Indian Journal of Critical Care Medicine: Peer-reviewed, Official … , 2011 2011 Citations: 15
Examining the social determinants of health in urban communities: A comparative analysis SV Kakade, TD Dabade, VC Patil, SN Ajani, A Bahulekar, R Sawant South Eastern European Journal of Public Health, 111-125 , 2023 2023 Citations: 14
