Medical image processing
Machine learning
Medical visualization
198
Scopus Publications
11798
Scholar Citations
50
Scholar h-index
137
Scholar i10-index
Scopus Publications
Combining shallow and deep neural networks on pseudo-color enhanced images for digital breast tomosynthesis lesion classification Zhikai Yang, Yingqing Liu, Örjan Smedby, Rodrigo Moreno Frontiers in Digital Health, 2026 Introduction The classification of lesion types in Digital Breast Tomosynthesis (DBT) images is crucial for the early diagnosis of breast cancer. However, the task remains challenging due to the complexity of breast tissue and the subtle nature of lesions. To alleviate radiologists’ workload, computer-aided diagnosis (CAD) systems have been developed. The breast lesion regions vary in size and complexity, which leads to performance degradation. Methods To tackle this problem, we propose a novel DBT Dual-Net architecture comprising two complementary neural network branches that extract both low-level and high-level features. By fusing different-level feature representations, the model can better capture subtle structure. Furthermore, we introduced a pseudo-color enhancement procedure to improve the visibility of lesions on DBT. Moreover, most existing DBT classification studies rely on two-dimensional (2D) slice-level analysis, neglecting the rich three-dimensional (3D) spatial context within DBT volumes. To address this limitation, we used majority voting for image-level classification from predictions across slices. Results We evaluated our method on a public DBT dataset and compared its performance with several existing classification approaches. The results showed that our method outperforms baseline models. Discussion The use of pseudo-color enhancement, extracting high and low-level features and inter-slice majority voting proposed method is effective for lesion classification in DBT. The code is available at https://github.com/xiaoerlaigeid/DBT-Dual-Net .
Anatomy-aware lymphoma lesion detection in whole-body PET/CT Simone Bendazzoli, Antonios Tzortzakakis, Andréas Abrahamsson, Björn Engelbrekt Wahlin, Örjan Smedby, Maria Holstensson, Rodrigo Moreno Frontiers in Oncology, 2026 Motivation and objectives Early cancer detection is essential for improving patient outcomes, and 18F-FDG PET/CT imaging plays a central role by combining metabolic and anatomical information. However, accurate lesion detection remains challenging due to the presence of multiple lesions with varying sizes and locations. This study investigates whether incorporating anatomical prior information can improve deep learning-based lesion detection performance. Methods Anatomical priors were incorporated by adding organ segmentation masks generated with TotalSegmentator as auxiliary input channels to two lesion detection frameworks: the CNN-based nnDetection and a transformer-based Swin UNETR implemented in MONAI. The Swin Transformer was trained using a two-stage strategy, with self-supervised pretraining performed on the autoPET dataset and supervised fine-tuning of the detector model conducted on the independent Karolinska lymphoma dataset. Model evaluation followed a single hold-out split, and performance was assessed using FROC and average precision metrics. Results Experiments were conducted on two independent PET/CT datasets covering different tracers and cancer subtypes. The autoPET dataset includes 18F-FDG PET/CT scans of lymphoma, melanoma, and lung cancer, while the Karolinska dataset focuses on lymphoma imaging. Incorporating anatomical priors consistently improved lesion detection performance within the nnDetection framework across both datasets. Specifically, nnDetection augmented with anatomical masks improved in mAP@0.1–0.5 from 0.288 to 0.335. In contrast, anatomical priors had minimal impact on the Swin Transformer, which did not demonstrate clear advantages over CNN-based encoders. Conclusions Anatomy-aware priors substantially enhance lesion detection performance in CNN-based models, highlighting the importance of explicit anatomical context for multi-lesion PET/CT analysis. However, these benefits do not readily transfer to transformer-based architectures, indicating the need for improved strategies to integrate anatomical information into vision transformers for medical image analysis.
Kinetic modelling of [⁶⁸Ga]Ga-FAPI-46 PET in pancreaticobiliary lesions: distinguishing cancer from pancreatitis Ted Nilsson, Pawel Rasinski, Ernesto Sparrelid, Antonios Tzortzakakis, Thuy A Tran, Örjan Smedby, Rimma Axelsson, Mark Lubberink, Maria Holstensson European Journal of Nuclear Medicine and Molecular Imaging, 2026 Purpose Fibroblast activation protein (FAP)–targeted PET using [⁶⁸Ga]Ga-FAPI-46 visualizes fibroblasts abundant in pancreatic cancer (PC) but also present in pancreatitis, complicating interpretation of static images. Dynamic imaging and kinetic modeling may provide additional insight, but their diagnostic value remains unclear. This study evaluated whether kinetic parameters from dynamic [⁶⁸Ga]Ga-FAPI-46 PET can differentiate PC from pancreatitis and their relationship with standardized uptake value (SUV) and tumor-to-blood ratio (TBR). Methods Sixty-one patients with suspected pancreaticobiliary cancer underwent a 45-min dynamic [⁶⁸Ga]Ga-FAPI-46 PET scan, followed by static scans at 60 and 180 min. Time–activity curves were generated for 51 malignant and 53 benign lesions. Compartment models and Logan analysis yielded kinetic parameters (K 1 , k 2 , k 3 , k 4 , V T , V NS , V S ). SUV and TBR were correlated with V T , and group comparisons and ROC analyses assessed discriminatory performance. Results Reversible models best described the tracer kinetics. V T and V S were significantly higher in PC than pancreatitis, and k 2 and k 4 were lower, indicating higher [⁶⁸Ga]Ga-FAPI-46 binding respectively slower washout in malignant lesions. SUV correlated strongly with V T ( r ≥ 0.784), and TBR showed very strong correlations ( r ≥ 0.902) for the 0–60 min interval, with strong correlations observed across all models and time points. ROC analyses demonstrated comparable differentiation between V T , SUV max , and TBR max . Conclusions Kinetic parameters showed strong correlations with simplified methods and similar ability to differentiate PC from pancreatitis. SUV and TBR measures thus represent practical alternatives to kinetic modelling for lesion characterization. ClinicalTrials.gov ID: NCT05172310
Decomposing the effect of normal aging and Alzheimer’s disease in brain morphological changes via learned aging templates Jingru Fu, Daniel Ferreira, Ö. Smedby, R. Moreno Scientific Reports, 2025 Alzheimer's disease (AD) subjects usually show more profound morphological changes with time compared to cognitively normal (CN) individuals. These changes are the combination of two major biological processes: normal aging and AD pathology. Investigating normal aging and residual morphological changes separately can increase our understanding of the disease. This paper proposes two scores, the aging score (AS) and the AD-specific score (ADS), whose purpose is to measure these two components of brain atrophy independently. For this, in the first step, we estimate the atrophy due to the normal aging of CN subjects by computing the expected deformation required to match imaging templates generated at different ages. We used a state-of-the-art generative deep learning model for generating such imaging templates. In the second step, we apply deep learning-based diffeomorphic registration to align the given image of a subject with a reference imaging template. Parametrization of this deformation field is then decomposed voxel-wise into their parallel and perpendicular components with respect to the parametrization of the expected atrophy of CN individuals in one year computed in the first step. AS and ADS are the normalized scores of these two components, respectively. We evaluated these two scores on the OASIS-3 dataset with 1,014 T1-weighted MRI scans. Of these, 326 scans were from CN subjects, and 688 scans were from subjects diagnosed with AD at various stages of clinical severity, as defined by clinical dementia rating (CDR) scores. Our results reveal that AD is marked by both disease-specific brain changes and an accelerated aging process. Such changes affect brain regions differently. Moreover, the proposed scores were sensitive to detect changes in the early stages of the disease, which is promising for its potential future use in clinical studies. Our code is freely available at https://github.com/Fjr9516/DBM_with_DL .
Two-Stage Convolutional Neural Network for Breast CT Reconstruction Zhikai Yang, Yihan Xiao, Ozan Öktem, Örjan Smedby, Rodrigo Moreno Progress in Biomedical Optics and Imaging Proceedings of SPIE, 2025 In this study, we propose a deep learning based two-stage breast CT reconstruction in the image domain. Unlike most methods, we use two separate models to improve the Breast CT image quality. In the first stage, a deep learning-based denoiser was used to remove the noise. In the second stage, a deep learning based image enhancement model is used to improve the image quality. We evaluated the proposed method on the AAPM 2021 sparse view CT reconstruction challenge dataset. The experimental results demonstrate that the proposed method performs better than all comparison methods.
Automatic Segmentation of Bone Graft in Maxillary Sinus via Distance Constrained Network Guided by Prior Anatomical Knowledge Jiangchang Xu, Jie Gao, Shuanglin Jiang, Chunliang Wang, Örjan Smedby, Yiqun Wu, Xiaoyi Jiang, Xiaojun Chen IEEE Journal of Biomedical and Health Informatics, 2025 Maxillary Sinus Lifting is a crucial surgical procedure for addressing insufficient alveolar bone mass andsevere resorption in dental implant therapy. To accurately analyze the geometry changesof the bone graft (BG) in the maxillary sinus (MS), it is essential to perform quantitative analysis. However, automated BG segmentation remains a major challenge due to the complex local appearance, including blurred boundaries, lesion interference, implant and artifact interference, and BG exceeding the MS. Currently, there are few tools available that can efficiently and accurately segment BG from cone beam computed tomography (CBCT) image. In this paper, we propose a distance-constrained attention network guided by prior anatomical knowledge for the automatic segmentation of BG. First, a guidance strategy of preoperative prior anatomical knowledge is added to a deep neural network (DNN), which improves its ability to identify the dividing line between the MS and BG. Next, a coordinate attention gate is proposed, which utilizes the synergy of channel and position attention to highlight salient features from the skip connections. Additionally, the geodesic distance constraint is introduced into the DNN to form multi-task predictions, which reduces the deviation of the segmentation result. In the test experiment, the proposed DNN achieved a Dice similarity coefficient of 85.48 6.38%, an average surface distance error is 0.57 0.34mm, and a 95% Hausdorff distance of 2.64 2.09mm, which is superior to the comparison networks. It markedly improves the segmentation accuracy and efficiency of BG and has potential applications in analyzing its volume change and absorption rate in the future.
Automated region growing-based segmentation for trabecular bone structure in fresh-frozen human wrist specimens Eva Klintström, Benjamin Klintström, Örjan Smedby, Rodrigo Moreno BMC Medical Imaging, 2024 Bone strength depends on both mineral content and bone structure. Measurements of bone microstructure on specimens can be performed by micro-CT. In vivo measurements are reliably performed by high-resolution peripheral computed tomography (HR-pQCT) using dedicated software. In previous studies from our research group, trabecular bone properties on CT data of defatted specimens from many different CT devices have been analyzed using an Automated Region Growing (ARG) algorithm-based code, showing strong correlations to micro-CT.The aim of the study was to validate the possibility of segmenting and measuring trabecular bone structure from clinical CT data of fresh-frozen human wrist specimens. Data from micro-CT was used as reference. The hypothesis was that the ARG-based in-house built software could be used for such measurements.HR-pQCT image data at two resolutions (61 and 82 µm isotropic voxels) from 23 fresh-frozen human forearms were analyzed. Correlations to micro-CT were strong, varying from 0.72 to 0.99 for all parameters except trabecular termini and nodes. The bone volume fraction had correlations varying from 0.95 to 0.98 but was overestimated compared to micro-CT, especially at the lower resolution. Trabecular separation and spacing were the most stable parameters with correlations at 0.80-0.97 and mean values in the same range as micro-CT.Results from this in vitro study show that an ARG-based software could be used for segmenting and measuring 3D trabecular bone structure from clinical CT data of fresh-frozen human wrist specimens using micro-CT data as reference. Over-and underestimation of several of the bone structure parameters must however be taken into account.
Correction to: Multi-cohort and longitudinal Bayesian clustering study of stage and subtype in Alzheimer’s disease (Nature Communications, (2022), 13, 1, (4566), 10.1038/s41467-022-32202-6) Konstantinos Poulakis, Joana B. Pereira, J.-Sebastian Muehlboeck, Lars-Olof Wahlund, Örjan Smedby, Giovanni Volpe, Colin L. Masters, David Ames, Yoshiki Niimi, Takeshi Iwatsubo, Daniel Ferreira, Eric Westman, , and Nature Communications, 2024 The original version of this Article contained an error in Tables 1, 3 and Supplementary Table S7 . In Table 1, the correct version of the 2nd row of the 1st column in both the Discovery dataset and Validation dataset states ‘females’ instead of the original, incorrect ‘males’. In Table 3, the correct version of the 2nd row of the 1st column states ‘females’ instead of the original, incorrect ‘males’. In Supplementary Table S7 the correct version of the 2nd row of the 1st column under both the ADNI and J-ADNI/AIBL headings states ‘females’ instead of the original, incorrect ‘males’.
Image quality assessments in abdominal CT: Relative importance of dose, iterative reconstruction strength and slice thickness B. Kataria, M. Woisetschläger, J. Nilsson Althén, M. Sandborg, Ö. Smedby Radiography, 2024 INTRODUCTION: Low contrast resolution in abdominal computed tomography (CT) may be negatively affected by attempts to lower patient doses. Iterative reconstruction (IR) algorithms play a key role in mitigating this problem. The reconstructed slice thickness also influences image quality. The aim was to assess the interaction and influence of patient dose, slice thickness, and IR strength on image quality in abdominal CT. METHOD: With a simultaneous acquisition, images at 42 and 98 mAs were obtained in 25 patients. Multiplanar images with slice thicknesses of 1, 2, and 3 mm and advanced modeled iterative reconstruction (ADMIRE) strengths of 3 (AD3) and 5 (AD5) were reconstructed. Four radiologists evaluated the images in a pairwise manner based on five image criteria. Ordinal logistic regression with mixed effects was used to evaluate the effect of tube load, ADMIRE strength, and slice thickness using the visual grading regression technique. RESULTS: For all assessed image criteria, the regression analysis showed significantly (p < 0.001) higher image quality for AD5, but lower for tube load 42 mAs, and slice thicknesses of 1 mm and 2 mm, compared to the reference categories of AD3, 98 mAs, and 3 mm, respectively. AD5 at 2 mm was superior to AD3 at 3 mm for all image criteria studied. AD5 1 mm produced inferior image quality for liver parenchyma and overall image quality compared to AD3 3 mm. Interobserver agreement (ICC) ranged from 0.874 to 0.920. CONCLUSION: ADMIRE 5 at 2 mm slice thickness may allow for further dose reductions due to its superiority when compared to ADMIRE 3 at 3 mm slice thickness. IMPLICATIONS FOR PRACTICE: Combination of thinner slices and higher ADMIRE strength facilitates imaging at low dose.
Multimodal brain tumor segmentation with normal appearance autoencoder Mehdi Astaraki, Chunliang Wang, Gabriel Carrizo, Iuliana Toma-Dasu, Örjan Smedby Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2020
Pelvis segmentation using multi-pass U-Net and iterative shape estimation Chunliang Wang, Bryan Connolly, Pedro Filipe de Oliveira Lopes, Alejandro F. Frangi, Örjan Smedby Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2019
A Two-Stage U-Net Algorithm for Segmentation of Nuclei in H&E-Stained Tissues Amirreza Mahbod, Gerald Schaefer, Isabella Ellinger, Rupert Ecker, Örjan Smedby, Chunliang Wang Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2019
Changes in brain architecture are consistent with altered fear processing in domestic rabbits Irene Brusini, Miguel Carneiro, Chunliang Wang, Carl-Johan Rubin, Henrik Ring, Sandra Afonso, José A. Blanco-Aguiar, Nuno Ferrand, Nima Rafati, Rafael Villafuerte, Örjan Smedby, Peter Damberg, Finn Hallböök, Mats Fredrikson, Leif Andersson Proceedings of the National Academy of Sciences of the United States of America, 2018
Feature space clustering for trabecular bone segmentation Benjamin Klintström, Eva Klintström, Örjan Smedby, Rodrigo Moreno Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2017
Granulometry-based trabecular bone segmentation Manish Chowdhury, Benjamin Klintström, Eva Klintström, Örjan Smedby, Rodrigo Moreno Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2017
Airway-tree segmentation in subjects with acute respiratory distress syndrome Kristína Lidayová, Duván Alberto Gómez Betancur, Hans Frimmel, Marcela Hernández Hoyos, Maciej Orkisz, et al. Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2017
Coverage segmentation of 3D thin structures Kristina Lidayova, Joakim Lindblad, Natasa Sladoje, Hans Frimmel, Chunliang Wang, et al. 5th International Conference on Image Processing Theory Tools and Applications 2015 Ipta 2015, 2015
Non-rigid deformation pipeline for compensation of superficial brain shift. Medical Image Computing and Computer Assisted Intervention Miccai International Conference on Medical Image Computing and Computer Assisted Intervention, 2013
Quantitative abdominal fat estimation using MRI O. Dahlqvist Leinhard, A. Johansson, J. Rydell, O. Smedby, F. Nystrom, et al. Proceedings International Conference on Pattern Recognition, 2008
MRI-guided celiac plexus block Per Kristian Hol, Gunnvald Kvarstein, Oddbj�rn Viken, �rjan Smedby, Tor Inge T�nnessen Journal of Magnetic Resonance Imaging, 2000
New presentation method for magnetic resonance angiography images based on skeletonization Proceedings of SPIE the International Society for Optical Engineering, 2000
Anatomical variations of the tympanic and mastoid portions of the facial nerve: Canal a radioanatomical investigation Acta Radiologica Supplement, 1996
A mathematical model for assessing mitral incompetence by videodensitometry Annales De Radiologie Medecine Nucleaire, 1981
RECENT SCHOLAR PUBLICATIONS
Kinetic modelling of [⁶⁸Ga] Ga-FAPI-46 PET in pancreaticobiliary lesions: distinguishing cancer from pancreatitis T Nilsson, P Rasinski, E Sparrelid, A Tzortzakakis, TA Tran, Ö Smedby, ... European Journal of Nuclear Medicine and Molecular Imaging, 1-11 , 2026 2026
DynamicBUS: Restoring Temporal Dynamics from Static Ultrasound for Improved Breast Cancer Diagnosis Z Yang, Y Liu, T Bai, A Biguri, H Chen, Y Li, CB Schönlieb, Ö Smedby, ... 2026
Anatomy-Aware Lymphoma Lesion Detection in Whole-Body PET/CT S Bendazzoli, A Tzortzakakis, A Abrahamsson, BE Wahlin, Ö Smedby, ... arXiv preprint arXiv:2511.07047 , 2025 2025
Two-stage convolutional neural network for breast CT reconstruction Z Yang, Y Xiao, O Öktem, Ö Smedby, R Moreno Medical Imaging 2025: Physics of Medical Imaging 13405, 815-820 , 2025 2025
Decomposing the effect of normal aging and Alzheimer’s disease in brain morphological changes via learned aging templates J Fu, D Ferreira, Ö Smedby, R Moreno Scientific Reports 15 (1), 11813 , 2025 2025 Citations: 8
Combining shallow and deep neural networks on pseudo-color enhanced images for digital breast tomosynthesis lesion classification Z Yang, Y Liu, Ö Smedby, R Moreno Frontiers in Digital Health 7, 1705044 , 2025 2025
Designing Radio-dynamics Features for PCR Prediction in Breast DCE-MRI S Bendazzoli, M Astaraki, Y Li, R Moreno, Ö Smedby, H Lu, C Wang 2025
Automatic segmentation of bone graft in maxillary sinus via distance constrained network guided by prior anatomical knowledge J Xu, J Gao, S Jiang, C Wang, Ö Smedby, Y Wu, X Jiang, X Chen IEEE journal of biomedical and health informatics 29 (3), 1995-2005 , 2024 2024 Citations: 4
Efficient Generation of Synthetic Breast CT Slices By Combining Generative and Super-Resolution Models Z Yang, M Astaraki, Ö Smedby, R Moreno Deep Breast Workshop on AI and Imaging for Diagnostic and Treatment … , 2024 2024 Citations: 1
Image quality assessments in abdominal CT: Relative importance of dose, iterative reconstruction strength and slice thickness B Kataria, M Woisetschläger, JN Althén, M Sandborg, Ö Smedby Radiography 30 (6), 1563-1571 , 2024 2024 Citations: 1
Acquisition Duration Optimization Using Visual Grading Regression in [68Ga] FAPI-46 PET Imaging of Oncologic Patients T Nilsson, P Rasinski, Ö Smedby, S Af Burén, E Sparrelid, JM Löhr, ... Journal of Nuclear Medicine Technology 52 (3), 221-228 , 2024 2024 Citations: 1
Author Correction: Multi-cohort and longitudinal Bayesian clustering study of stage and subtype in Alzheimer’s disease K Poulakis, JB Pereira, JS Muehlboeck, LO Wahlund, Ö Smedby, G Volpe, ... nature communications 15 (1), 5784 , 2024 2024
Lung vessel connectivity map as anatomical prior knowledge for deep learning-based lung lobe segmentation S Bendazzoli, E Bäcklin, Ö Smedby, B Janerot-Sjoberg, B Connolly, ... Journal of Medical Imaging 11 (4), 044001-044001 , 2024 2024 Citations: 5
Pulmonary volumes and signs of chronic airflow limitation in quantitative computed tomography E Bäcklin, A Gonon, M Sköld, Ö Smedby, E Breznik, B Janerot‐Sjoberg Clinical Physiology and Functional Imaging 44 (4), 340-348 , 2024 2024
Unsupervised domain adaptation for pediatric brain tumor segmentation J Fu, S Bendazzoli, Ö Smedby, R Moreno arXiv preprint arXiv:2406.16848 , 2024 2024 Citations: 14
3D breast ultrasound image classification using 2.5 D deep learning Z Yang, T Fan, Ö Smedby, R Moreno 17th International Workshop on Breast Imaging (IWBI 2024) 13174, 443-449 , 2024 2024 Citations: 9
Automated region growing-based segmentation for trabecular bone structure in fresh-frozen human wrist specimens E Klintström, B Klintström, Ö Smedby, R Moreno BMC Medical Imaging 24 (1), 101 , 2024 2024 Citations: 4
Lesion localization in digital breast tomosynthesis with deformable transformers by using 2.5 D information Z Yang, T Fan, Ö Smedby, R Moreno Medical Imaging 2024: Computer-Aided Diagnosis 12927, 84-89 , 2024 2024 Citations: 4
Using simulated breast lesions based on Perlin noise for evaluation of lesion segmentation H Tomic, Z Yang, A Tingberg, S Zackrisson, R Moreno, Ö Smedby, ... Medical Imaging 2024: Physics of Medical Imaging 12925, 279-288 , 2024 2024 Citations: 1
Image quality in CT thorax: effect of altering reconstruction algorithm and tube load B Kataria, M Woisetschläger, J Nilsson Althén, M Sandborg, Ö Smedby Radiation Protection Dosimetry 200 (5), 504-514 , 2024 2024 Citations: 3
MOST CITED SCHOLAR PUBLICATIONS
Identifying the best machine learning algorithms for brain tumor segmentation, progression assessment, and overall survival prediction in the BRATS challenge S Bakas, M Reyes, A Jakab, S Bauer, M Rempfler, A Crimi, RT Shinohara, ... arXiv preprint arXiv:1811.02629 , 2018 2018 Citations: 2829
A multi-organ nucleus segmentation challenge N Kumar, R Verma, D Anand, Y Zhou, OF Onder, E Tsougenis, H Chen, ... IEEE transactions on medical imaging 39 (5), 1380-1391 , 2019 2019 Citations: 687
Standardized evaluation methodology and reference database for evaluating coronary artery centerline extraction algorithms M Schaap, CT Metz, T van Walsum, AG van der Giessen, AC Weustink, ... Medical image analysis 13 (5), 701-714 , 2009 2009 Citations: 458
Evaluation of algorithms for multi-modality whole heart segmentation: an open-access grand challenge X Zhuang, L Li, C Payer, D Štern, M Urschler, MP Heinrich, J Oster, ... Medical image analysis 58, 101537 , 2019 2019 Citations: 427
MRBrainS challenge: online evaluation framework for brain image segmentation in 3T MRI scans AM Mendrik, KL Vincken, HJ Kuijf, M Breeuwer, WH Bouvy, J De Bresser, ... Computational intelligence and neuroscience 2015 (1), 813696 , 2015 2015 Citations: 344
Web‐based interactive 3D visualization as a tool for improved anatomy learning H Petersson, D Sinkvist, C Wang, Ö Smedby Anatomical sciences education 2 (2), 61-68 , 2009 2009 Citations: 342
Advanced 3D visualization in student-centred medical education C Silén, S Wirell, J Kvist, E Nylander, Ö Smedby Medical teacher 30 (5), e115-e124 , 2008 2008 Citations: 215
Synthetic MRI of the brain in a clinical setting I Blystad, JBM Warntjes, O Smedby, AM Landtblom, P Lundberg, ... Acta radiologica 53 (10), 1158-1163 , 2012 2012 Citations: 197
Iodinated contrast opacification gradients in normal coronary arteries imaged with prospectively ECG-gated single heart beat 320-detector row computed tomography ML Steigner, D Mitsouras, AG Whitmore, HJ Otero, C Wang, O Buckley, ... Circulation: Cardiovascular Imaging 3 (2), 179-186 , 2010 2010 Citations: 197
A novel infraclavicular brachial plexus block: the lateral and sagittal technique, developed by magnetic resonance imaging studies Ø Klaastad, HJ Smith, Ö Smedby, EH Winther-Larssen, P Brodal, ... Anesthesia & Analgesia 98 (1), 252-256 , 2004 2004 Citations: 138
Two-dimensional tortuosity of the superficial femoral artery in early atherosclerosis Ö Smedby, N Högman, S Nilsson, U Erikson, AG Olsson, G Walldius Journal of vascular research 30 (4), 181-191 , 1993 1993 Citations: 134
Quantifying differences in hepatic uptake of the liver specific contrast agents Gd-EOB-DTPA and Gd-BOPTA: a pilot study O Dahlqvist Leinhard, N Dahlström, J Kihlberg, P Sandström, TB Brismar, ... European radiology 22 (3), 642-653 , 2012 2012 Citations: 130
Standardized evaluation system for left ventricular segmentation algorithms in 3D echocardiography O Bernard, JG Bosch, B Heyde, M Alessandrini, D Barbosa, ... IEEE transactions on medical imaging 35 (4), 967-977 , 2015 2015 Citations: 128
Quantitative MRI for analysis of peritumoral edema in malignant gliomas I Blystad, JBM Warntjes, Ö Smedby, P Lundberg, EM Larsson, A Tisell PLoS One 12 (5), e0177135 , 2017 2017 Citations: 122
Contrast-enhanced magnetic resonance cholangiography with Gd-BOPTA and Gd-EOB-DTPA in healthy subjects N Dahlström, A Persson, N Albiin, Ö Smedby, TB Brismar Acta Radiologica 48 (4), 362-368 , 2007 2007 Citations: 122
Visual grading regression: analysing data from visual grading experiments with regression models Ö Smedby, M Fredrikson The British journal of radiology 83 (993), 767-775 , 2010 2010 Citations: 109
Quantitative abdominal fat estimation using MRI OD Leinhard, A Johansson, J Rydell, O Smedby, F Nystrom, P Lundberg, ... 2008 19th international conference on pattern recognition, 1-4 , 2008 2008 Citations: 108
A computational atlas of normal coronary artery anatomy P Medrano-Gracia, J Ormiston, M Webster, S Beier, A Young, C Ellis, ... EuroIntervention 12 (7), 845-854 , 2016 2016 Citations: 106
Do plaques grow upstream or downstream? An angiographic study in the femoral artery O Smedby Arteriosclerosis, thrombosis, and vascular biology 17 (5), 912-918 , 1997 1997 Citations: 104
Multi-cohort and longitudinal Bayesian clustering study of stage and subtype in Alzheimer’s disease K Poulakis, JB Pereira, JS Muehlboeck, LO Wahlund, Ö Smedby, G Volpe, ... Nature communications 13 (1), 4566 , 2022 2022 Citations: 103