Hélio Plapler

Scopus Publications

Photobiomodulation Modulates Proliferation and Gene Expression Related to Calcium Signaling in Human Osteoblast Cells
Journal of Lasers in Medical Sciences, 2024
Photobiomodulation effect in tumoral necrosis factor-alpha(TNF-α) on the viability of random skin flap in rats
Georgia Rodrigues Esteves, Ivaldo Esteves Junior, Igor Fagioli Bordello Masson, Aline Fernanda Perez Machado, Maria Carolina Derencio Oliveira, et al.
Lasers in Medical Science, 2022
Photobiomodulation of Matrix Metalloproteinases in Rat Calcaneal Tendons
Julio Fernandes de Jesus, Diva Denelle Spadacci-Morena, Nayra Deise dos Anjos Rabelo, Carlos Eduardo Pinfildi, Thiago Yukio Fukuda, et al.
Photobiomodulation Photomedicine and Laser Surgery, 2019
Objective: The main objective was to verify the modulatory effects of MMP-1, MMP-3, and MMP-13 levels on the partially injured calcaneal tendons of rat exposure to photobiomodulation. Background: Photobiomodulation has been shown to have anti-inflammatory and regenerative effects on tendon injuries. However, there is still uncertainty regarding the beneficial effects in matrix metalloproteinase (MMP) levels, especially MMP-1, -3, and -13. Materials and methods: Sixty-five male Wistar rats were used. Sixty were submitted to a direct trauma on the calcaneal tendons and were randomly distributed into the following six groups: LASER 1, 3, and 7 (10 partially injured calcaneal tendons in each group treated with photobiomodulation for 1, 3, and 7 days, respectively) and Sham 1, 3, and 7 (same injury, with simulated photobiomodulation). The remaining five animals were allocated to the normal group (no injury or treatment procedure). The 780 nm low-level laser was applied with 70 mW of mean power and 17.5 J/cm2 of fluency for 10 sec, once a day. The tendons were surgically removed and analyzed for MMP-1, MMP-3, and MMP-13 through immunohistochemistry. Results: MMP-3 levels remained close to normal in all experimental groups (p > 0.05); however, reductions (p < 0.05) in MMP-1 and MMP-13 levels were detected in the groups submitted to one, three, and seven low level laser therapy applications. Conclusions: The photobiomodulation protocol was able to reduce MMP-1 and MMP-13 levels in injured calcaneal tendons.
The role of dimethoate and UV-B on skin of Wistar rats
TANIA RITA MORENO DE OLIVEIRA FERNANDES, CELINA TIZUKO FUJIYAMA OSHIMA, LEONARDO CARDILI, DANIEL ARAKI RIBEIRO, MARCELO SOUZA SILVA, et al.
Anticancer Research, 2019
Background/Aim: The pesticide dimethoate (O-dimethyl-S- Nmethylcarbamoylmethyl phosphorodithioate) is able to induce severe acute toxicity in living organisms. The aim of this study was to evaluate the effects of ultraviolet radiation, alone or combined with exposure to dimethoate, on the rat skin. Materials and Methods: A total of 38 Wistar female rats (Rattus norvegicus albinus), were distributed into four groups: A (n=9) control group, B (n=10) exposed to ultraviolet-B radiation (UV-B), C (n=10) exposed to UV-B followed by application of dimethoate (UV-B+AGRO) and group D (n=9) exposed to dimethoate (AGRO). Histological examination of the tissues, as well as immunohistochemistry for cleaved caspase 3, Ki-67 and COX-2 expression were performed to all groups. Results: Animals submitted to UV-B exhibited hyperkeratosis with moderate cell atypia. Regarding exposure to UV-B+AGRO, the animals presented hyperkeratosis and atrophy, whereas in animals exposed to AGRO, only atrophy was noticed. The immunohistochemical results on skin revealed that UVB, AGRO and UVB+AGRO decreased cleaved caspase 3 and Ki-67 expression when compared to the control group (p<0.05). COX-2 expression decreased to UVB or AGRO groups compared to controls (p<0.05). Conclusion: UV-B or AGRO exposure is able to induce histopathological changes and altered expression of cleaved caspase-3 and Ki-67 in rat skin, thus being categorized as a risk condition for skin carcinogenesis.
Effect of low power laser in biomodulation of cultured osteoblastic cells of wistar rats
Maria Jose Misael da Silva Morsoleto, Valeria Sella, Paula Machado, Fernando do Bomfim, Maria Helena Fernandes, et al.
Acta Cirurgica Brasileira, 2019
Purpose To analyze aspects of the biomodulating effect of light in biological tissues, bone cells from surgical explants of the femur of rats were irradiated with low intensity laser. Methods Bone cells were cultured and irradiated with LASER light (GaAlAs). Growth, cell viability, mineralized matrix formation, total protein dosage, immunostimulatory properties, cytochemical analysis, gene expression of bone proteins were examined using live cell imaging and cell counting by colorimetric assay. The gene expression of: alkaline phosphatase (ALP), type 1 collagen, osteocalcin and osteopontin through the real-time polymerase chain reaction. Results At 8 days, the viability of the irradiated culture was 82.3% and 72.4% in non-irradiated cells. At 18 days, the cellular viability (with laser) was 77.42% and 47.62% without laser. At 8 days, the total protein concentration was 21.622 mg / mol in the irradiated group and 16, 604 mg / mol in the non-irradiated group and at 18 days the concentration was 37.25 mg / mol in the irradiated group and 24, 95 mg / mol in the non-irradiated group. Conclusion The laser interfered in the histochemical reaction, cell viability, matrix mineralization, and maintained the cellular expression of proteins
Dosimetry of a Carbon Dioxide Laser for Black Tattoo Removal in a Rat Model
Fabio D'Arienzo, Fernando Russo Costa do Bomfim, Valéria Regina Gonzalez Sella, Manuel de Jesus Simões, Hélio Plapler
Photomedicine and Laser Surgery, 2018
OBJECTIVE To determine the optimal parameters of power, energy, and time for the application of a carbon dioxide laser for Tribal Black ink tattoo removal. BACKGROUND DATA The use of antiquated techniques to remove tattoos demonstrates the difficulty of making advances in this field. Studies by the American Society for Dermatologic Surgery have shown that 5% of the global population has at least one tattoo on the body, with 10% of them wanting a tattoo to be removed. Laser removal has been studied and improved as a less invasive and safer method of surgical removal; however, the ideal dosimetry is not yet established. MATERIALS AND METHODS Thirty-three male Wistar rats were anesthetized and tattooed in the dorsal region in a quadrangular manner. The rats were distributed under low/null luminosity for 4 months into three equal and random groups for the application of the laser, namely, G1 (P = 0.6 W, Et = 0.9 J), G2 (P = 0.8 W, Et = 1, 2 J), and G3 (P = 1 W, Et = 1.5 J), with the application time standardized to 0.15 sec with 10 passes per application. The procedure was repeated at intervals of 4 weeks until 10 cycles of laser application were completed. The images were studied using the ImageJ program and histological analysis and subjected to the one-way ANOVA test for Tukey's multiple comparison post-test. RESULTS We observed a significant difference between groups 1 and 3 and between groups 2 and 3. CONCLUSIONS The laser with the parameters of P = 1 W, Et = 1.5 J, and t = 0.15 sec yields better Tribal Black ink removal results.
Influence of low-level laser irradiation on osteocalcin protein and gene expression in bone tissue
Fernando Russo Costa do Bomfim, Valeria Regina Gonzalez Sella, Ronaldo Luís Thomasini, Helio Plapler
Acta Cirurgica Brasileira, 2018
PURPOSE To evaluate osteocalcin gene and protein expression in vitro and in an in vivo model of ostectomy. METHODS Twenty Wistar rats were assigned into two groups A (n=10, laser) and B (n=10, control). Ostectomy was performed in the femur diaphysis; the twenty fragments removed, composed in vitro groups named as in vivo (A and B) and cultivated in CO2 atmosphere for thirteen days. Low-level laser irradiation was performed in groups A (in vivo and in vitro) by an GaAlAs device (λ=808 nm, dose of 2J/cm2, power of 200mW, power density of 0.2W/cm2, total energy of 1.25J, spot diameter of 0.02mm) for 5 seconds, at one point, daily. It was performed immunocytochemistry assays in vivo and in vitro groups. In vitro groups were also submitted to RNA extraction, cDNA synthesis and gene expression by quantitative PCR. Statistical analysis was realized with p<0.05. RESULTS Immunocytochemistry scores showed no significant differences between control and laser groups either in vivo and in vitro. Gene expression also showed no statistical differences. CONCLUSION Low-level laser irradiation did not alter osteocalcin protein and gene expression in vivo and in vitro in the studied period but it may have been expressed them in an earlier period.
Low-Level Laser Therapy (780 nm) on VEGF Modulation at Partially Injured Achilles Tendon
Julio Fernandes de Jesus, Diva Denelle Spadacci-Morena, Nayra Deise dos Anjos Rabelo, Carlos Eduardo Pinfildi, Thiago Yukio Fukuda, et al.
Photomedicine and Laser Surgery, 2016
OBJECTIVE The aim of this study was to analyze the modulatory effects of near infrared (780 nm) low-level laser therapy (LLLT) on the presence of the vascular endothelial growth factor (VEGF) in the partially injured Achilles tendons of rats. BACKGROUND LLLT stimulates the healing process for Achilles tendon injuries, although the extent of the modulatory effect of LLLT on the VEGF levels found in the injured tendons remains unclear. METHODS Sixty-five male Wistar rats were distributed in the following seven groups: LASER 1, 3, and 7 (10 partially injured Achilles tendons in each group, which were treated with LLLT for 1, 3, and 7 days, respectively); Sham 1, 3, and 7 (same injury, with simulated LLLT); Control group containing the five remaining animals and in which no procedures were performed. LLLT was applied once a day for 10 sec, with a mean power of 70 mW and fluency of 17.5 J/cm(2). After euthanasia, all of the Achilles tendons were surgically removed and the VEGF levels were analyzed using immunohistochemistry. RESULTS The VEGF levels remained close to normal (p > 0.05) when comparing the experimental groups (LASER and Sham: 1, 3, and 7) with the Control group. CONCLUSION LLLT did not stimulate the expression of VEGF in the treated Achilles tendons.
Evaluation of different laser wavelengths on ablation lesion and residual thermal injury in intervertebral discs of the lumbar spine
Hélio Plapler, Marília W. Mancini, Valéria R. G. Sella, Fernando R. C. Bomfim
Lasers in Medical Science, 2016
Morphological and functional response to injury to the external urethral sphincter - Similarities and differences between male and female rats
Scheila F. C. Nascimento, Ana Paula S. Bispo, Katia Ramos Leite, Helio Plapler, Claudius Füllhase, et al.
Neurourology and Urodynamics, 2016
The objective of this study was to evaluate the similarities and differences of the urethral morphological and functional changes following external urethral sphincter EUS injury in male and female rats.
Real time echo-guided endolaser for thermal ablation without perivenous tumescence
Ricardo José Gaspar, André Nóbrega Castro, Manuel de Jesus Simões, Hélio Plapler
Jornal Vascular Brasileiro, 2015
Effect of low-level laser therapy on bone repair: a randomized controlled experimental study
Valéria Regina Gonzalez Sella, Fernando Russo Costa do Bomfim, Paula Carolina Dias Machado, Maria José Misael da Silva Morsoleto, Milton Chohfi, et al.
Lasers in Medical Science, 2015
Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon
Julio Fernandes de Jesus, Diva Denelle Spadacci-Morena, Nayra Deise dos Anjos Rabelo, Carlos Eduardo Pinfildi, Thiago Yukio Fukuda, et al.
Lasers in Medical Science, 2015
Low-level laser therapy on tissue repair of partially injured achilles tendon in rats
Julio Fernandes de Jesus, Diva Denelle Spadacci-Morena, Nayra Deise dos Anjos Rabelo, Carlos Eduardo Pinfildi, Thiago Yukio Fukuda, et al.
Photomedicine and Laser Surgery, 2014
Cutaneous changes in rats induced by chronic skin exposure to ultraviolet radiation and organophosphate pesticide
Tania Rita Moreno de Oliveira Fernandes, Itamar Santos, Juliana Pedrosa Korinsfky, Benedyto Savio Lima e Silva, Luis Otavio Carvalho, et al.
Acta Cirurgica Brasileira, 2014
Induction of neoplastic cells in rat skin
Juliana Pedrosa Korinfsky, Hélio Plapler, Tania Rita Moreno, Itamar Santos, Celeste Maria
Acta Cirurgica Brasileira, 2014
RT-PCR standardization and bone mineralization after low-level laser therapy on adult osteoblast cells
Fernando R. C. do Bomfim, Valéria R. G. Sella, Jéssica Q. Zanaga, Nayara S. Pereira, Viviane L. A. Nouailhetas, et al.
Progress in Biomedical Optics and Imaging Proceedings of SPIE, 2014
Infrared low-level diode laser on serum chemokine MCP-1 modulation in mice
Thiago Y. Fukuda, Maury M. Tanji, Julio Fernandes de Jesus, Suélen Rocha da Silva, Maria N. Sato, et al.
Lasers in Medical Science, 2013
Infrared low-level diode laser on inflammatory process modulation in mice: Pro- and anti-inflammatory cytokines
Thiago Y. Fukuda, Maury M. Tanji, Suélen R. Silva, Maria N. Sato, Hélio Plapler
Lasers in Medical Science, 2013
Low level laser therapy (AlGaInP) applied at 5J/cm2 reduces the proliferation of Staphylococcus aureus MRSA in infected wounds and intact skin of rats
Daniela Conceição Gomes Gonçalves e Silva, Helio Plapler, Mateus Matiuzzi da Costa, Silvio Romero Gonçalves e Silva, Maria da Conceição Aquino de Sá, et al.
Anais Brasileiros De Dermatologia, 2013
Pharmacokinetics of photogem using fluorescence spectroscopy in dimethylhydrazine-induced murine colorectal carcinoma
Raduan Hage, Juliana Ferreira, Vanderlei Salvador Bagnato, José Dirceu Vollet-Filho, Hélio Plapler
International Journal of Photoenergy, 2012
Low-level laser irradiation, cyclooxygenase-2 (COX-2) expression and necrosis of random skin flaps in rats
Ivaldo Esteves Junior, Igor B. Masson, Celina T. F. Oshima, Ana Paula R. Paiotti, Richard E. Liebano, et al.
Lasers in Medical Science, 2012
Single session to infrared low level diode laser on TNF-α and IL-6 cytokines release by mononuclear spleen cells in mice: A pilot study
Thiago Y. Fukuda, Maury M. Tanji, Julio F. Jesus, Maria N. Sato, Alberto J.S. Duarte, et al.
Lasers in Surgery and Medicine, 2010
Effects of low-level laser therapy on collagen expression and neutrophil infiltrate in 5-fluorouracil-induced oral mucositis in hamsters
Nilza Nelly Fontana Lopes, Hélio Plapler, Rajesh V. Lalla, Maria Cristina Chavantes, Elisabeth Mateus Yoshimura, et al.
Lasers in Surgery and Medicine, 2010
Calibration of low-level laser therapy equipment
Thiago Y. Fukuda, Julio F. Jesus, Marcio G. Santos, Claudio Cazarini Junior, Maury M. Tanji, et al.
Revista Brasileira De Fisioterapia, 2010
A new method for hemorrhoid surgery: Intrahemorrhoidal diode laser, does it work?
Hélio Plapler, Raduan Hage, Janaina Duarte, Nilza Lopes, Igor Masson, et al.
Photomedicine and Laser Surgery, 2009
Tribute to Prof. Saul Goldenberg
Hélio Plapler
Acta Cirurgica Brasileira, 2009
A study of actinic cheilitis treatment by two low-morbidity CO2 laser vaporization one-pass protocols
Flávio Francisco de Godoy Peres, Adriana Aigotti Haberbeck Brandão, Yasmin Rodarte Carvalho, Ulysses Dória Filho, Hélio Plapler
Lasers in Medical Science, 2009
Cyclooxygenase-2 and vascular endothelial growth factor expression in 5-fluorouracil-induced oral mucositis in hamsters: Evaluation of two low-intensity laser protocols
Nilza Nelly Fontana Lopes, Hélio Plapler, Maria Cristina Chavantes, Rajesh V. Lalla, Elisabeth Mateus Yoshimura, et al.
Supportive Care in Cancer, 2009
Photodynamic therapy (PDT) to treat a chronic skin wound in a dog
Raduan Hage, Hélio Plapler, Renata A. Bitar
Progress in Biomedical Optics and Imaging Proceedings of SPIE, 2008
A new method for hemorrhoid surgery: Experimental model of diode laser application in monkeys
Hélio Plapler
Photomedicine and Laser Surgery, 2008
Photodynamic Therapy (PDT) using intratumoral injection of the 5-aminolevulinic acid (5-ALA) for the treatment of eye cancer in cattle
Raduan Hage, Geraldo Mancilha, Renato A. Zângaro, Egberto Munin, Hélio Plapler
Progress in Biomedical Optics and Imaging Proceedings of SPIE, 2007
Analysis of colon tumors in rats by near-infrared Raman spectroscopy
Janaína Duarte, Raduan Hage, Landulfo Silveira, Jr., Fabricio Silveira, Marcos Tadeu T. Pacheco, et al.
Progress in Biomedical Optics and Imaging Proceedings of SPIE, 2007
Analysis of the photo-dynamic therapy by using chloroaluminum phthalocyanine incorporated into and fractionation energy in colon tumors of rats
Janaina Duarte, Raduan Hage, Antonio C. Tedesco, Marcelo Pazos, Airton A. Martin, et al.
Progress in Biomedical Optics and Imaging Proceedings of SPIE, 2006
Hemorrhoids: An experimental model in monkeys
Hélio Plapler
Acta Cirurgica Brasileira, 2006
Web-based learning in undergraduate medical education: Development and assessment of an online course on experimental surgery
Viviane Bernardo, Monica Parente Ramos, Helio Plapler, Luiz Francisco Poli de Figueiredo, Helena B. Nader, et al.
International Journal of Medical Informatics, 2004
350 Ambulatory hemorrhoidectomies using a scanner coupled to a CO2 laser
HÉLIO PLAPLER, ALBERTO JORGE DE FARIA NETTO, MARCELO DA SILVA PEDRO
Journal of Clinical Laser Medicine and Surgery, 2000
Evaluation of the longitudinal musculature of segments of the distal colon interposed following extended jejunum-ileum resection
Murched Omar Taha, Marcelo A.F. Ribeiro, Paulo de Oliveira Gomes, Edna Montero Frasson, H�lio Plapler, et al.
Microsurgery, 1999
Effects of ethanol on energy balance of rats and the inappropriateness of intraperitoneal injection
J. Luz, M.A. Griggio, H. Plapler, M. De-Meo-Bancher, J.V. Carvalho-Kosmiskas
Alcohol, 1996
Graft-infiltrating cells in rats receiving orthotopic semiallogeneic small intestine transplantation with portal or systemic venous drainage
B. Sullivan, Z. Cohen, X-M. Fu, G. Levy, H. Plapler, et al.
Transplantation, 1996
Phenotypic and functional assessment of intraepithelial lymphocytes (IEL) isolated from rat colon and small bowel
Reginald M. Gorczynski, Zhiqi Chen, Zane Cohen, Helio Plapler, David Wojcik
Immunology Letters, 1996
Phenotypic and functional assessment of intraepithelial lymphocytes (IEL) isolated from rat colon and small bowel
Regional Immunology, 1994
Graft-infiltrating cells in small intestinal transplants of rats with portal or inferior vena cava drainage
Transplantation Proceedings, 1994
Hepatic regulation of lymphocyte-endothelial cell interaction
Transplantation Proceedings, 1994
Hepatic regulation of lymphocyte adhesion to, and activation on, syngeneic endothelial monolayers
Immunology, 1994
Colonic fermentation and nutritional recovery in rats with massive small bowel resection
Elaheh Aghdassi, Helio Plapler, Regina Kurian, Nilima Raina, Dawna Royall, et al.
Gastroenterology, 1994
Colon transplantation: A new microvascular technique
Hélio Plapler, Zane Cohen
Microsurgery, 1993
Altered cell trafficking of mesenteric lymphocytes after heterotopic small bowel transplantation using systemic venous drainage
Transplantation Proceedings, 1993
Functional activity in host and graft lymphoid tissue of rats receiving syngeneic heterotopic small bowel transplants with portal or systemic drainage
R.M. Gorczynski, Z. Cohen, H. Plapler, G. Levy, D. Wojcik, et al.
Immunology Letters, 1993
Migration patterns of lymphocytes following syngeneic heterotopic small bowel transplantation in rodents
I. Koh, Z. Cohen, G. Levy, H. Plapler, D. Wojcik, et al.
Immunology Letters, 1993
Effects of ofloxacin over the experimental inflammation in rats
Arquivos Brasileiros De Medicina, 1992
Glucose absorption by the interposed colon segment after intestinal resection.
Revista Espanola De Fisiologia, 1992
Small bowel and colon glucose absorption study in rats by an adaptation of Sols and Ponz method.
Revista Espanola De Fisiologia, 1991
Transcolonoscopic extraperitoneal cecostomy. A new therapeutic and technical proposal
A. J. Ganc, A. J. Faria Netto, A. C. Morrell, H. Plapler, J. C. Ardengh
Endoscopy, 1988

MOST CITED SCHOLAR PUBLICATIONS

A new method for hemorrhoid surgery: intrahemorrhoidal diode laser, does it work?
H Plapler, R Hage, J Duarte, N Lopes, I Masson, C Cazarini, T Fukuda
Photomedicine and laser surgery 27 (5), 819-823 , 2009
2009
Citations: 139
Cyclooxygenase-2 and vascular endothelial growth factor expression in 5-fluorouracil-induced oral mucositis in hamsters: evaluation of two low-intensity laser protocols
NNF Lopes, H Plapler, MC Chavantes, RV Lalla, EM Yoshimura, ...
Supportive care in cancer 17 (11), 1409-1415 , 2009
2009
Citations: 134
Web-based learning in undergraduate medical education: development and assessment of an online course on experimental surgery
V Bernardo, MP Ramos, H Plapler, LFP De Figueiredo, HB Nader, ...
International journal of medical informatics 73 (9-10), 731-742 , 2004
2004
Citations: 130
Effect of low-level laser therapy on bone repair: a randomized controlled experimental study
VRG Sella, FRC do Bomfim, PCD Machado, MJM da Silva Morsoleto, ...
Lasers in medical science 30 (3), 1061-1068 , 2015
2015
Citations: 113
Effects of low‐level laser therapy on collagen expression and neutrophil infiltrate in 5‐fluorouracil‐induced oral mucositis in hamsters
NNF Lopes, H Plapler, RV Lalla, MC Chavantes, EM Yoshimura, ...
Lasers in surgery and medicine 42 (6), 546-552 , 2010
2010
Citations: 108
Infrared low-level diode laser on inflammatory process modulation in mice: pro-and anti-inflammatory cytokines
TY Fukuda, MM Tanji, SR Silva, MN Sato, H Plapler
Lasers in Medical Science 28 (5), 1305-1313 , 2013
2013
Citations: 93
A new method for hemorrhoid surgery: experimental model of diode laser application in monkeys
H Plapler
Photomedicine and Laser Surgery 26 (2), 143-146 , 2008
2008
Citations: 54
Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon
JF de Jesus, DD Spadacci-Morena, ND dos Anjos Rabelo, CE Pinfildi, ...
Lasers in medical science 30 (1), 153-158 , 2015
2015
Citations: 47
Low level laser therapy (AlGaInP) applied at 5J/cm 2 reduces the proliferation of Staphylococcus aureus MRSA in infected wounds and intact skin of rats
DCGG Silva, H Plapler, MM Costa, SRG Silva, MCA Sá, BSL Silva
Anais brasileiros de dermatologia 88, 50-55 , 2013
2013
Citations: 33
Low-level laser irradiation, cyclooxygenase-2 (COX-2) expression and necrosis of random skin flaps in rats
I Esteves Junior, IB Masson, CTF Oshima, APR Paiotti, RE Liebano, ...
Lasers in medical science 27 (3), 655-660 , 2012
2012
Citations: 33
350 Ambulatory Hemorrhoidectomies Using a Scanner Coupled to a CO 2 Laser
H Plapler, AJ de Faria Netto, M da Silva Pedro
Journal of clinical laser medicine & surgery 18 (5), 259-262 , 2000
2000
Citations: 33
Colonic fermentation and nutritional recovery in rats with massive small bowel resection
E Aghdassi, H Plapler, R Kurian, N Raina, D Royall, KN Jeejeebhoy, ...
Gastroenterology 107 (3), 637-642 , 1994
1994
Citations: 33
Single session to infrared low level diode laser on TNF‐α and IL‐6 cytokines release by mononuclear spleen cells in mice: A pilot study
TY Fukuda, MM Tanji, JF Jesus, MN Sato, AJS Duarte, H Plapler
Lasers in Surgery and Medicine 42 (6), 584-588 , 2010
2010
Citations: 29
Low-level laser therapy on tissue repair of partially injured achilles tendon in rats
JF de Jesus, DD Spadacci-Morena, NDA Rabelo, CE Pinfildi, TY Fukuda, ...
Photomedicine and laser surgery 32 (6), 345-350 , 2014
2014
Citations: 28
Localização de lesões tumorais induzidas pela 1, 2-dimetilhidrazina e seu grau de atipia no cólon de ratos
LLS Larangeira, MO Taha, A Ferme, R Lemos, H Plapler
Acta Cirúrgica Brasileira 13 (3), 177-182 , 1998
1998
Citations: 26
Transcolonoscopic extraperitoneal cecostomy
AJ Ganc, AJF Netto, AC Morrell, H Plapler, JC Ardengh
Endoscopy 20 (06), 309-312 , 1988
1988
Citations: 23
Effect of low power laser in biomodulation of cultured osteoblastic cells of Wistar rats
MJMS Morsoleto, V Sella, P Machado, F Bomfim, MH Fernandes, ...
Acta cirurgica brasileira 34 (02), e201900210 , 2019
2019
Citations: 20
A study of actinic cheilitis treatment by two low-morbidity CO 2 laser vaporization one-pass protocols
FF de Godoy Peres, A Aigotti Haberbeck Brandão, Y Rodarte Carvalho, ...
Lasers in medical science 24 (3), 375-385 , 2009
2009
Citations: 20
Evaluation of different laser wavelengths on ablation lesion and residual thermal injury in intervertebral discs of the lumbar spine
H Plapler, MW Mancini, VRG Sella, FRC Bomfim
Lasers in medical science 31 (3), 421-428 , 2016
2016
Citations: 18
Photobiomodulation of matrix metalloproteinases in rat calcaneal tendons
J Fernandes de Jesus, DD Spadacci-Morena, NDA Rabelo, CE Pinfildi, ...
Photobiomodulation, photomedicine, and laser surgery 37 (7), 421-427 , 2019
2019
Citations: 17

Hélio Plapler

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

MOST CITED SCHOLAR PUBLICATIONS