Karen de Jesus Nicácio has graduation at Química from Universidade Estadual de Santa Cruz (2006-2010), master's at Chemistry from Universidade de São Paulo (2010-2012) and doctorate at Chemistry from Universidade de São Paulo (2013-2017) focused on Marine Natural Products Chemistry. The master's and doctorate were carried out with funding from a CAPES scholarship, under the guidance of Prof. Dr. Roberto Gomes de Souza Berlinck. After her doctorate, she worked on the Cristália Produtos Químicos e Farmacêuticos group in partnership with the University of São Paulo and worked as a substitute professor at the Federal Institute of São Paulo. Worked as a substitute professor and post-doc researcher at Unifal-MG, under the supervision of Professor Daniela Aparecida Chagas Paula. Currently, she acts as a professor at the Federal University of Mato Grosso - UFMT, Cuiabá campus
The Metabolome of the Ocotea spp.: From Biosynthetic Aspects to Bioactive Chemical Scaffolds by Integrating the Genus Chemical Database ( Ocotea DB) A Katchborian-Neto, K de Jesus Nicácio, PCP Bueno, MS Ferreira, ... Journal of Natural Products , 2026 2026
Phytotoxic Metabolites from Hyptis Species: Chemical Profiling and Bioherbicide Activity Against Amaranthus MA Silva, LPF da Silva, KJ Nicácio, BS Bellete, LCC Vieira, OM Sampaio ACS omega 10 (42), 50359-50370 , 2025 2025
NMR Analysis and Assignment of a Biosynthesis Gene Cluster for Trichokonins VI and VIII, Antiplasmodial Large Peptaibols Produced by a Trichoderma sp. Fungus AF Bertonha, DE Williams, KJ Nicacio, MR Amorim, SM Schoellhorn, ... ACS omega 10 (41), 48293-48307 , 2025 2025
Metabolomics of Trichoderma spirale by Mass Spectrometry Data Dereplication M de Arruda Silva, LPF da Silva, ACR dos Santos, ACM Rocha, ... Chemistry of Natural Compounds, 1-7 , 2025 2025
Metabolomics and dereplication strategies for the study of bioactive metabolites derived from plants and fungi PCP Bueno, K de Jesus Nicácio, DA Chagas-Paula Fitoterapia, 106375 , 2025 2025
Identification and biosynthesis of peptaibols Trichokonins VI and VIII with antiplasmodial activity M Gotha, AF Bertonha, DE Williams, KJ Nicácio, MR Amorim, ... Book of Abstracts , 2025 2025
Bioguided isolation of anti-inflammatory and anti-urolithiatic active compounds from the decoction of Cissus gongylodes leaves PPO Salem, DO Silva, PRS Silva, LPDM Costa, KJ Nicácio, M Murgu, ... Journal of Ethnopharmacology, 118950 , 2024 2024 Citations: 4
Novel Synthesized Benzophenone Thiazole Hybrids Exhibited Ex Vivo and In Silico Anti-Inflammatory Activity LPM de Oliveira Leão, AK Neto, K de Jesus Nicácio, SN Lavorato, ... Chemical biology & drug design 104 (4), e14634 , 2024 2024
Biological and metabolomics-guided isolation of tetrahydrofurofuran lignan from Croton spp. with antiproliferative activity against human melanoma cell line DA Garcia, CG Pressete, R Miranda, PPO Salem, KJ Nicácio, ... Fitoterapia, 106070 , 2024 2024 Citations: 1
Untargeted Metabolomic to Access Chemical Differences Induced by Dual Endophyte Cultures Isolated from Euphorbia umbellata AS Gusmão, JCS Conceição, SM de Queiros Santos, CLS Pereira, ... Chemistry & Biodiversity, e202400395 , 2024 2024 Citations: 3
Integrative open workflow for confident annotation and molecular networking of metabolomics MS E /DIA data A Katchborian-Neto, MF Alves, PCP Bueno, K de Jesus Nicácio, ... Briefings in Bioinformatics 25 (2), bbae013 , 2024 2024 Citations: 14
Phytochemical investigation of Nigrospora zimmermanii isolated from Poincianella pluviosa (Sibipiruna): metabolites characterisation and screening for anti … MS Ferreira, A Katchborian-Neto, KJ Nicácio, MFC Santos, DF Dias, ... Natural Product Research, 1-7 , 2024 2024 Citations: 4
Potential anti-inflammatory biomarkers from Myrtaceae essential oils revealed by untargeted metabolomics TCS Maiolini, KJ Nicácio, W Rosa, DO Miranda, MFC Santos, PCP Bueno, ... Natural Product Research, 1-8 , 2023 2023 Citations: 12
Polyketide- and Terpenoid-Derived Metabolites Produced by a Marine-Derived Fungus, Peroneutypa sp. MR de Amorim, CS Barbosa, TA Paz, LP Ióca, KJ Nicácio, LFP de Oliveira, ... Journal of Natural Products , 2023 2023 Citations: 12
Evaluation of the anti-inflammatory activity of Acacia polyphylla and identification of a new apigenin-3- C - glycosylated type flavonoid D de Oliveira Silva, MF Conceição Santos, K de Jesus Nicácio, AK Neto, ... Natural Product Research, 1-6 , 2023 2023 Citations: 5
Water-Soluble Metabolites Isolated from Cultures of an Unidentified Marine-Derived Fungal Strain GC Junqueira, RG de Souza Berlinck, MR de Amorim, L Ioca, ... Galoá , 2023 2023
DETERMINAÇÃO DE COMPOSTOS FENÓLICOS EM FRUTAS NATIVAS DO CERRADO BRASILEIRO BAO MOTTA, LC COSTA, KJ NICÁCIO, GA LEMES, MCL MENDONCA, ... Galoá , 2023 2023
Development of Ex-Vivo Anti-inflammatory Assay for screening of activity through PGE2 and LTB4 release inhibition G Viana, A Katchborian-Neto, K de Jesus Nicácio, PCP Bueno, DF Dias, ... Galoá , 2023 2023
Advancements in QSAR modelling: Decision trees and rotation forest for prediction of Aspergillus anti-inflammatory metabolites MS Ferreira, AK Neto, VVM Paixão, K de Jesus Nicácio, MFC Santos, ... Galoá , 2023 2023
Metabolomic Guided Isolation of Epi-yangambin from Croton ssp. with Antiproliferative Activity in Melanoma Cell Line D Garcia, C Pressete, R Miranda, PP de Oliveira Salem, ... Galoá , 2023 2023
MOST CITED SCHOLAR PUBLICATIONS
Isolation, synthesis and bioactivity studies of phomactin terpenoids Y Kuroda, KJ Nicacio, IA da Silva-Jr, PR Leger, S Chang, JR Gubiani, ... Nature chemistry 10 (9), 938-945 , 2018 2018.0 Citations: 100
Cultures of the Marine Bacterium Pseudovibrio denitrificans Ab134 Produce Bromotyrosine-Derived Alkaloids Previously Only Isolated from Marine Sponges KJ Nicacio, LP Ióca, AM Fróes, L Leomil, LR Appolinario, CC Thompson, ... Journal of Natural Products 80 (2), 235-240 , 2017 2017.0 Citations: 88
Neuroprotective potential of Ayahuasca and untargeted metabolomics analyses: applicability to Parkinson's disease A Katchborian-Neto, WT Santos, KJ Nicácio, JOA Corrêa, M Murgu, ... Journal of Ethnopharmacology 255, 112743 , 2020 2020.0 Citations: 86
Condensation of Macrocyclic Polyketides Produced by Penicillium sp. DRF2 with Mercaptopyruvate Represents a New Fungal Detoxification Pathway MV de Castro, LP Ióca, DE Williams, BZ Costa, CM Mizuno, MFC Santos, ... Journal of natural products 79 (6), 1668-1678 , 2016 2016.0 Citations: 53
A STRATEGY FOR THE RAPID IDENTIFICATION OF FUNGAL METABOLITES AND THE DISCOVERY OF THE ANTIVIRAL ACTIVITY OF PYRENOCINE A AND HARZIANOPYRIDONE LP Ióca, S Romminger, MFC Santos, KF Bandeira, FT Rodrigues, ... Química Nova 39 (6), 720-731 , 2016 2016.0 Citations: 27
Anti‐Inflammatory Markers of Hops Cultivars ( Humulus lupulus L.) Evaluated by Untargeted Metabolomics Strategy KJ Nicacio, MS Ferreira, A Katchborian‐Neto, ML Costa, M Murgu, ... Chemistry & Biodiversity 19 (4), e202100966 , 2022 2022.0 Citations: 25
Natural Products from Marine Invertebrates and Microorganisms in Brazil between 2004 and 2017: Still the Challenges, More Rewards LP Ióca, KJ Nicacio, RGS Berlinck Citations: 23
Metabolomics Reveals Minor Tambjamines in a Marine Invertebrate Food Chain M Takaki, VF Freire, KJ Nicacio, AF Bertonha, N Nagashima, R Sarpong, ... Journal of Natural Products 84 (3), 790-796 , 2020 2020.0 Citations: 21
Anti-urolithiatic and anti-inflammatory activities through a different mechanism of actions of Cissus gongylodes corroborated its ethnopharmacological historic PPO Salem, NB Vieira, DA Garcia, KJ Nicácio, DF Dias, ACC de Paula, ... Journal of Ethnopharmacology 253, 112655 , 2020 2020.0 Citations: 18
Integrative open workflow for confident annotation and molecular networking of metabolomics MS E /DIA data A Katchborian-Neto, MF Alves, PCP Bueno, K de Jesus Nicácio, ... Briefings in Bioinformatics 25 (2), bbae013 , 2024 2024.0 Citations: 14
Potential anti-inflammatory biomarkers from Myrtaceae essential oils revealed by untargeted metabolomics TCS Maiolini, KJ Nicácio, W Rosa, DO Miranda, MFC Santos, PCP Bueno, ... Natural Product Research, 1-8 , 2023 2023.0 Citations: 12
Polyketide- and Terpenoid-Derived Metabolites Produced by a Marine-Derived Fungus, Peroneutypa sp. MR de Amorim, CS Barbosa, TA Paz, LP Ióca, KJ Nicácio, LFP de Oliveira, ... Journal of Natural Products , 2023 2023.0 Citations: 12
Bioprospecting-Based Untargeted Metabolomics Identifies Alkaloids as Potential Anti-Inflammatory Bioactive Markers of Ocotea Species (Lauraceae) A Katchborian-Neto, K de Jesus Nicácio, JC Cruz, M Murgu, DF Dias, ... Available at SSRN 4488850 , 0 Citations: 12
Chemistry of leaves, bark, and essential oils from Ocotea diospyrifolia and anti-inflammatory activity–Dual inhibition of edema and neutrophil recruitment AF Silva, MFC Santos, TSC Maiolini, PPO Salem, M Murgu, ACC Paula, ... Phytochemistry Letters 42, 52-60 , 2021 2021.0 Citations: 10
Fluorescence spectroscopy and confocal microscopy of the mycotoxin citrinin in condensed phase and hydrogel films MH Lauer, MH Gehlen, K de Jesus, RGS Berlinck Journal of fluorescence 24 (3), 745-750 , 2014 2014.0 Citations: 8
Fast and Efficient Method to Obtain Tagitinin F by Photocyclization of Tagitinin C VHC Fernandes, NB Viera, LBL Zanini, AF Silva, PPO Salem, MG Soares, ... Photochemistry and Photobiology 96 (1), 14-20 , 2020 2020.0 Citations: 6
Evaluation of the anti-inflammatory activity of Acacia polyphylla and identification of a new apigenin-3- C - glycosylated type flavonoid D de Oliveira Silva, MF Conceição Santos, K de Jesus Nicácio, AK Neto, ... Natural Product Research, 1-6 , 2023 2023.0 Citations: 5
Bioguided isolation of anti-inflammatory and anti-urolithiatic active compounds from the decoction of Cissus gongylodes leaves PPO Salem, DO Silva, PRS Silva, LPDM Costa, KJ Nicácio, M Murgu, ... Journal of Ethnopharmacology, 118950 , 2024 2024.0 Citations: 4
Phytochemical investigation of Nigrospora zimmermanii isolated from Poincianella pluviosa (Sibipiruna): metabolites characterisation and screening for anti … MS Ferreira, A Katchborian-Neto, KJ Nicácio, MFC Santos, DF Dias, ... Natural Product Research, 1-7 , 2024 2024.0 Citations: 4
Untargeted Metabolomic to Access Chemical Differences Induced by Dual Endophyte Cultures Isolated from Euphorbia umbellata AS Gusmão, JCS Conceição, SM de Queiros Santos, CLS Pereira, ... Chemistry & Biodiversity, e202400395 , 2024 2024.0 Citations: 3
