Prachitee Borkar

@smcw.edu.in

Assistant Professor, Pharmacology
Symbiosis Medical College For Women

Prachitee Borkar


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https://researchid.co/prachitee.borkar

EDUCATION

M.Sc. (Medical Pharmacology)

RESEARCH INTERESTS

Pharmacoeconomics, Cancer Pharmacology/therapeutics

FUTURE PROJECTS

AI assisted segregation of biomedical waste


Applications Invited
2

Scopus Publications

34

Scholar Citations

3

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • Cisplatin Resistance in Ovarian Cancer: Classical Outlook and Newer Perspectives
    Prachitee Borkar, Prasan Bhandari, Shraddha Yadav, Ashwini Prabhu
    Biomedical and Pharmacology Journal, 2021
    Ovarian cancer is one of the most common gynecological cancers. Recently, there is increase in incidence of ovarian cancer not only India but also worldwide. Ovarian cancer patients exhibit nonspecific symptoms during early course of disease. As a consequence, 70% of these patients are diagnosed in advanced stages. Ovarian cancer treatment includes cytoreductive surgery followed by platinum-based chemotherapy. However, these patients develop fatal recurrence due to development of platinum resistance. Cisplatin, (platinum analog) resistance is multifactorial and complex. Earlier, resistance was mainly attributed to conventional molecular mechanisms like decreased intracellular accumulation of cisplatin, enhanced DNA repair and increased cisplatin detoxification. Nevertheless, emergence of knowledge of tumor biology have lead to discovery of other contributing mechanisms. These tumor microenvironment related factors include physical blockade, hypoxia, cancer stem cells, cancer associated fibroblasts and many others. Understanding these mechanisms of cisplatin resistance is crucial for development of novel strategy to combat the same. Hence, this review summarizes all the mechanisms of resistance of cisplatin in ovarian cancer.
  • Development of a teaching module for parenteral drug administration and objective structured practical examination stations in pharmacology
    Vasudha Devi, Prachitee Upadhye, Pradhum Ram, RiteshG Menezes
    Indian Journal of Pharmacology, 2013
    Objectives: Safe parenteral drug administration includes preparation of safe medication for administration. Training medical students is crucial to minimize medication administration errors. The study aims to develop a module to teach drug preparation skills and to develop objective structured practical examination (OSPE) stations to assess these skills. Students’ perceptions regarding the module were also assessed. Materials and Methods: A module was developed to teach following skills to 2nd year medical students: Aspiration of a drug from the ampule, aspiration of the drug from the vial, aspiration of the drug in powdered form from vial (reconstitution), and setting up an intravenous (IV) infusion. A randomized case control study design was used to establish the validity of OSPE stations. Student volunteers were grouped into case (n = 20) and control groups (n = 20) by simple randomization. The test group watched videos of skills and received demonstration of skills and a practice session before OSPE, whereas the control group watched videos before the OSPE and received demonstration and a practice session only after the OSPE. Each student was assessed by two faculty members during OSPE using a validated checklist. Mean OSPE scores of control and test groups were compared using independent samples t-test. Interrater reliability and concurrent validity of stations were analyzed using interclass correlation coefficient (ICC) and Pearson correlation, respectively. Students’ responses were expressed as median and interquartile range. Results: The response rate in the questionnaire was 100%. Significant difference between mean scores (P < 0.05) of test and control groups revealed fulfillment of construct validity of OSPE stations. Interrater reliability (ICC > 0.7) and concurrent validity (r value > 7) of all the stations was high. Perceptions revealed acceptability of module and OSPE stations by students (median 4, scale 1-5). Conclusions: A module to teach drug preparation skills was developed and along with valid and reliable OSPE stations that were acceptable to students. The study demonstrated that students acquire better skills through teaching than merely watching these skills in videos.

RECENT SCHOLAR PUBLICATIONS

  • Awareness Of Health Benefits of Yoga Among Medical Undergraduates: Knowledge, Attitude & Practice Based Study
    PB Viraj Ashok Shinde1 , Kantilal Chandaliya2 , Neha Kakirde3 , Latesh B ...
    Afr. J. Biomed. Res 27 (December 2024), 2250-2255 , 2024
    2024.0
    Citations: 3
  • Variation of Cost Among Oral Hypoglycaemic Drugs Available in Indian Market in 2020-21.
    RJ Patil, P Borkar, PR Bhandari, VA Shinde
    Indian Journal of Pharmaceutical Sciences 85 (6) , 2023
    2023.0
  • A pharmacoeconomic outlook of the biological drugs marketed in India: a cost variance analysis
    VA Shinde, R Patil, P Bhandari, P Borkar, S Yadav
    Cureus 15 (1) , 2023
    2023.0
    Citations: 4
  • Impact of National List of Essential Medicines (NLEM) on Cost variation of Immunosuppressants available in Indian Market
    P Borkar, V Shinde, B Prasan, P Ramanand
    Journal of Young Pharmacists 14 (3), 310-313 , 2022
    2022.0
  • Cisplatin resistance in ovarian cancer: Classical outlook and newer perspectives
    P Borkar, P Bhandari, S Yadav, A Prabhu
    Biomedical and Pharmacology Journal 14 (4), 1993-2005 , 2021
    2021.0
    Citations: 13
  • Development of a teaching module for parenteral drug administration and objective structured practical examination stations in pharmacology
    V Devi, P Upadhye, P Ram, RG Menezes
    Indian journal of pharmacology 45 (6), 587-592 , 2013
    2013.0
    Citations: 13
  • Formulation and standardization of calendula officinalis for wound healing
    SM Lande, KJ Metkari, KD Lavate, IR Raut, JI Shaikh
    Citations: 1

MOST CITED SCHOLAR PUBLICATIONS

  • Cisplatin resistance in ovarian cancer: Classical outlook and newer perspectives
    P Borkar, P Bhandari, S Yadav, A Prabhu
    Biomedical and Pharmacology Journal 14 (4), 1993-2005 , 2021
    2021.0
    Citations: 13
  • Development of a teaching module for parenteral drug administration and objective structured practical examination stations in pharmacology
    V Devi, P Upadhye, P Ram, RG Menezes
    Indian journal of pharmacology 45 (6), 587-592 , 2013
    2013.0
    Citations: 13
  • A pharmacoeconomic outlook of the biological drugs marketed in India: a cost variance analysis
    VA Shinde, R Patil, P Bhandari, P Borkar, S Yadav
    Cureus 15 (1) , 2023
    2023.0
    Citations: 4
  • Awareness Of Health Benefits of Yoga Among Medical Undergraduates: Knowledge, Attitude & Practice Based Study
    PB Viraj Ashok Shinde1 , Kantilal Chandaliya2 , Neha Kakirde3 , Latesh B ...
    Afr. J. Biomed. Res 27 (December 2024), 2250-2255 , 2024
    2024.0
    Citations: 3
  • Formulation and standardization of calendula officinalis for wound healing
    SM Lande, KJ Metkari, KD Lavate, IR Raut, JI Shaikh
    Citations: 1
  • Variation of Cost Among Oral Hypoglycaemic Drugs Available in Indian Market in 2020-21.
    RJ Patil, P Borkar, PR Bhandari, VA Shinde
    Indian Journal of Pharmaceutical Sciences 85 (6) , 2023
    2023.0
  • Impact of National List of Essential Medicines (NLEM) on Cost variation of Immunosuppressants available in Indian Market
    P Borkar, V Shinde, B Prasan, P Ramanand
    Journal of Young Pharmacists 14 (3), 310-313 , 2022
    2022.0