Dr Anup Naha

@manipal.edu

Associate Professor, Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences
Manipal Academy of Higher Education

RESEARCH INTERESTS

Nanotechnology, Novel Drug Delivery System, Sports Pharmacy
58

Scopus Publications

830

Scholar Citations

13

Scholar h-index

19

Scholar i10-index

Scopus Publications

  • Exploiting the role of milk extracellular vesicles: a comprehensive analysis on isolation methods, characterization, surface modifications, and their therapeutic applications
    Mahananda R. Prabhu, Dinesh Upadhya, Harishkumar Madhyastha, Anup Naha, Haribalan Perumalsamy, Sneha Sunderraj, Akhilesh Dubey, Shadi Rahimi, Sri Renukadevi Balusamy, Srinivas Hebbar
    Journal of Nanobiotechnology, 2026
    Milk EVs (MEVs) are a class of extracellular vesicles (EVs) that have attracted significant attention for their potential as natural nanocarriers in drug delivery. These nanosized vesicles (30 - 150 nm) are composed of a lipid bilayer that encapsulates proteins, nucleic acids, and lipids. The biogenesis of EVs involves a tightly regulated “endocytosis-fusion-secretion” pathway, and they are secreted by diverse cells into physiological fluids (blood, urine, and saliva). The isolation and characterization methods of MEVs are essential to achieve high purity, structural integrity, size distribution, and biomolecular composition. Efficient drug loading strategies such as passive diffusion, electroporation, and sonication enable the incorporation of therapeutic molecules. Surface modifications such as PEGylation, ligand conjugation, and genetic engineering further enhance the targeting efficiency, circulation stability, and therapeutic efficacy. Given their biocompatibility, low immunogenicity, and natural ability to traverse biological barriers, MEVs offer a scalable, and non-toxic platform for targeted drug delivery such as span cancer therapy, neurodegenerative disease treatment, and immune modulation. However, further research is needed to optimize MEV-based therapeutics, ensuring their efficacy and safety through rigorous clinical trials. This review explores the biogenesis, composition, isolation, characterization, drug-loading strategies, surface modifications, and therapeutic applications of MEVs, highlighting their emerging role in nanomedicine. Graphical abstract
  • A Study on Quality Assurance and Utilization of Equipment in the Radiology Department of a Tertiary Care Teaching Hospital
    P. Arathi, Anup Naha, Siva Kumar, Usha Rani
    Hospital Topics, 2026
    Utilizing resources to reduce costs and increase income while ensuring patient safety necessitates rigorous planning. The study aims to assess ergonomics, equipment utilization, outpatient satisfaction, and quality assurance in the Radiology Department. Four hundred outpatients, 39 radiographers, and 40 postgraduate students participated in a cross-sectional mixed-methods study that included surveys and interviews. The results were obtained using descriptive statistics, a utilization rate, and a Chi-square test with a 95% confidence interval. Three hundred eighty-two patients, or 95.5%, were satisfied with the overall service quality. Quality and explanation of the process by a radiographer 76.8%, patient knowledge of procedures 76.8%, privacy level 79%, and affordability of treatment 91.8% leading to 95.5% patient satisfaction and 87% were willing to recommend the facility to family and friends. Although there was a high percentage correlation with clinical diagnosis (81%), re-doing 43 (1%), reporting a mistake 30 (23.4%), or both might affect patient safety standards. Quality control, patient safety, and equipment utilization are all inextricably linked. Even minor changes in quality can influence utilization rates and patient safety.
  • Thermotropic liquid crystals for precision drug delivery and diagnostics: Molecular design, characterization, and clinical translation
    Anjana A. Kailas, K.A. Abutwaibe, Poornima Bhagavath, Debanjan Bhattacharjee, Annamalai Rama, Induja Govindan, Thamizharasan Annadurai, Anup Naha
    Journal of Applied Pharmaceutical Science, 2026
    Thermoresponsive drug delivery systems offer precise, on-demand, and site-specific release of therapeutic agents in response to temperature changes, thereby enhancing drug stability, minimizing side effects, and improving patient compliance. Among these, thermotropic liquid crystals (TLCs) represent a unique class of temperature-dependent mesophases with tunable properties, extended-release profiles, and targeted delivery capabilities. This review provides an in-depth examination of thermoresponsive mesophases, with a particular focus on TLCs, exploring their fundamental chemistry, structural characteristics, and adaptability in pharmaceutical sciences. A comprehensive literature survey was conducted using Scopus, PubMed, and Web of Science to analyze recent advancements in TLC-based drug delivery, biomedical applications, and associated challenges. The review discusses the mechanisms by which TLC mesophases enable thermoresponsive and sustained drug administration, as well as their integration into biosensors and diagnostic platforms, highlighting their broader biomedical potential. Key formulation strategies are outlined, alongside major obstacles such as toxicity, formulation complexity, stability, scalability, and regulatory considerations that must be addressed for clinical translation. The article also showcases recent developments and future directions in this rapidly evolving field, emphasizing the need for biocompatible and scalable TLC systems. By addressing a significant gap in the application of thermotropic mesophases specifically for drug delivery, this review underscores the promise of TLCs as intelligent drug carriers and multifunctional biomedical materials, while also identifying critical areas for future research and development.
  • Targeted Delivery of Quercetin to the Brain via a Modified Polymeric Nanocarrier
    Priyanshu Bhadane, Aniket Khairnar, Kalpana Pandya, Anup Naha, Dileep Kumar, K. A. Abutwaibe, Jiya Desai, Nilesh Bombatkar, Prabha Rajput, Devendra Kumar
    Macromolecular Bioscience, 2026
    Quercetin (Qt) exhibits significant neuroprotective potential in Alzheimer's disease; however, its clinical translation is limited by poor solubility, low permeability, and inadequate brain bioavailability. In this study, a modified polymeric nanocarrier was developed to enhance Qt delivery to the brain. Polyethyleneimine (PEI) was conjugated with polyethylene glycol (PEG) and further functionalized with phenylalanine to reduce PEI‐associated toxicity and improve brain‐targeting efficiency. Successful polymer synthesis was confirmed by FT–IR spectroscopy, showing characteristic S─S bond formation at 790 cm − 1 , mass spectrometry (m/z 1087.3), and differential scanning calorimetry. Nanoparticles were optimized using a Quality by Design approach, yielding an experimental particle size of 161.4 ± 1.10 nm, zeta potential of 15.9 ± 2.5 mV, and high entrapment efficiencies of 84.21 % and 86.74 % for Qt‐PEI‐Np and Qt‐PEI‐PEG‐S‐S‐AA‐Np, respectively. SEM analysis revealed spherical nanoparticles with nanoscale surface roughness and good stability. In vitro release studies demonstrated sustained Qt release (98 % over 48 h). MTT assays and cytokine analysis (TNF‐α, IL‐1β, IL‐6) confirmed biocompatibility. Enhanced intestinal permeability, absence of hippocampal toxicity, and effective BBB transport further support the potential of this nanocarrier for targeted neurotherapeutic delivery.
  • Structured engineering of self-emulsifying drug delivery systems (SEDDS) via 3D printing: Comprehensive review
    Induja Govindan, Anjana A. Kailas, K.A. Abutwaibe, Thamizharasan Annadurai, Ujwala Achar, Anup Naha, Srinivas Hebbar
    International Journal of Pharmaceutics X, 2025
    The combination of self-emulsifying drug delivery systems (SEDDS) with three-dimensional printing (3DP) technologies represents an innovative and promising strategy for developing personalised dosage forms. Through precise control over dosage form architecture, controlled drug release kinetics, and individualised therapeutic customisation, 3DP offers distinct and transformative advantages over conventional pharmaceutical formulation approaches. This review focuses on the application of modern 3DP techniques, specifically fused deposition modelling (FDM), semi-solid extrusion (SSE), and drop-on-demand (DoD), in the formulation and production of SEDDS. Each technique is critically evaluated in terms of formulation compatibility, operational mechanisms, and its potential to address the current manufacturing challenges associated with SEDDS. 3DP technologies offer several benefits, including enhanced flexibility in production, the ability to fabricate on demand, and the potential to accommodate complex and personalised therapeutic regimens. However, these methods also face notable limitations, such as material constraints, variability in print quality, mechanical and safety issues, and a lack of clear regulatory guidance. Despite their potential, the use of 3DP in SEDDS development remains relatively unexplored. This review aims to provide a comprehensive overview of the current research landscape, identify existing technological and regulatory barriers, and discuss future prospects for integrating 3DP into next-generation SEDDS formulations.
  • Density functional theory analysis of two fluorinated liquid crystalline materials: a comprehensive study
    Kritika Garg, Jakub Herman, Anup Naha, Debanjan Bhattacharjee
    Discover Applied Sciences, 2025
    The article analyses two fluorinated liquid crystal molecules, A and B, through density functional theory simulations. Their structures were optimized using the B3LYP functional and the 6-31+G (d, p) basis set. The research assessed the impact of fluorine substitution and alkyl chains on the energies of the highest occupied molecular orbital and the lowest vacant molecular orbital. A comparison analysis was performed on electrostatic potential energies, atomic polar tensors, and Mulliken charges to elucidate the dynamic behaviour and charge distribution of these compounds. Furthermore, polarisability and hyperpolarizability were analysed concerning nonlinear optical properties. Additional physical features, including dipole moment, reactivity parameters, and thermodynamic characteristics, were examined to further understanding of phase transitions and dynamics in fluorinated liquid crystals A and B. The electron localisation function and localised orbital locator investigations provide insights into electron localisation and delocalisation inside the compounds. This comparative analysis of fluorine substitution in compounds A and B uncovers novel prospects for advanced optoelectronic devices and molecular dynamics.
  • HPLC-BASED BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF POSACONAZOLE IN SPIKED RAT PLASMA
    INDUJA GOVINDAN, ANJANA A. KAILAS, ABUTWAIBE KA, THAMIZHARASAN ANNADURAI, ANUP NAHA
    International Journal of Applied Pharmaceutics, 2025
    Objective: Posaconazole (PSC), a highly effective broad-spectrum triazole antifungal, is widely used to treat invasive fungal infections. Accurate and consistent quantification of PSC in biological matrices, such as plasma, is vital for supporting pharmacokinetic and therapeutic drug monitoring studies. To develop and validate a sensitive, robust, and sustainable bioanalytical HPLC method for the quantification of posaconazole in plasma. Methods: The method utilises a simple protein precipitation technique for sample preparation, avoiding more hazardous or solvent-intensive procedures. Chromatographic separation was achieved using an isocratic elution with a mobile phase composed of acetonitrile and water acidified with 0.5% acetic acid (44:56), delivered at a flow rate of 0.7 ml/min. Unlike most reported methods that use phosphate buffers, this method employs water acidified with 0.5% v/v of acetic acid, enhances environmental compatibility and avoids buffer salt disposal and system fouling issues. Detection was performed at 262 nm using a Shimadzu LC-2010CHT system with a dual-wavelength UV detector and a photodiode array (SPD-M20A, Prominence series). Results: The method exhibited excellent linearity over the 0.25–32 µg/ml range (r² = 0.9999). Intra and inter-day precision and accuracy complied with ICH M10 bioanalytical validation guidelines, with %RSD values below 2% and recoveries ranging from 97.7±0.07 to 101.12±0.03%. Stability under all relevant conditions was confirmed. Environmental sustainability was evaluated using AGREE and GAPI tools, an approach not previously applied to posaconazole bioanalysis, highlighting its novelty and sustainable design for routine use. Conclusion: A validated bioanalytical HPLC method for posaconazole quantification in plasma was successfully developed, is suitable for routine pharmacokinetic and therapeutic drug monitoring applications.
  • LIPID-POLYMER HYBRID NANOPARTICLES AND SILICA-BASED HYBRID NANOPARTICLES FOR CANCER TREATMENT
    ANJANA A. KAILAS, ANNAMALAI RAMA, BHAUTIK LADANI, INDUJA GOVINDAN, K. A. ABUTWAIBE, ANUP NAHA
    International Journal of Applied Pharmaceutics, 2025
    The development of complex nanoparticles with enhanced tumor therapy selectivity and effectiveness is now achievable thanks to nanotechnology. Despite the vast number of nanostructures, such as liposomes, solid-lipid nanoparticles, Lipid-Polymer Hybrid Nanoparticles (LPHNPs), and Silica-based Hybrid Nanoparticles (SHNPs), have been developed as carriers for drug delivery for different pathologies with remarkably promising results. In the present study, we have discussed simple and efficient preparation methods for lipid-polymer and silica-based nanoparticles. These methods reduce the potential for toxicity as the drug molecules can be delivered to the pharmacological sites of action at an optimal controlled rate. With adequate preparation methods, lipid hybrid and silica-based nanoparticles can be developed to reduce adverse effects. Significant improvement has been made in preparing and functionalizing the hybrid nanoparticle for advancing cancer treatment. Studies prove that LPHNPs have exhibited drug-loading efficiency of around 60-70%, which is more than liposomal systems. The ability of these nanoparticles to circulate through the Reticulo-Endothelial System (RES) also results in a significant increase in circulation time, with a half-life of up to 12 h. These hybrid nanoparticles with high drug loading efficiency and specific targeting efficiency can help precisely target the tumor cells.
  • Impact of fluorine substitution on benzene ring in two fluorinated liquid crystal compounds: a comprehensive analysis using TG-DTA, FT-IR, UV, and PED techniques
    Kritika Garg, Adrish Chakraborty, Marta Żak, Jakub Herman, Anup Naha, Debanjan Bhattacharjee
    Discover Applied Sciences, 2025
    The main objective in this article is to examine the impact of the fluorine atom on the benzene ring in two liquid crystal compounds that have undergone fluorination. Given that fluorine is a highly electronegative element, it improves the physical properties of liquid crystal compounds. The characteristics of the mentioned compounds have been investigated using FT-IR, UV–Vis, thermogravimetry differential thermal analysis (TG-DTA), and the potential energy distribution function of IR spectra. The ambient comparative theoretical and experimental analysis of the two substances, two different basis sets is carried out using DFT. With the basis sets 6-311 + G (d, p) and 6-31 + G (d, p), the TD-DFT/B3LYP approach was used for describing the theoretical UV–Vis spectra of these compounds. Based on experimental and theoretical investigation, both molecules show high compatibility with both the basis sets. The PED (potential energy distribution) function exhibits good agreement when detailed vibrational allocations are made using VEDA (Vibrational energy distribution analysis) software. This enhances comprehension of the diverse dynamical properties and more research into the numerous optical and electrical applications of liquid crystals. The FT-IR and UV–Vis spectra of both compounds are helpful in evaluating various vibrational modes and spectral properties.
  • Mesogenic Architectures for Advanced Drug Delivery: Interrogating Lyotropic and Thermotropic Liquid Crystals
    Induja Govindan, Angeeta Paul, Annamalai Rama, Anjana A. Kailas, K. A. Abutwaibe, Thamizharasan Annadurai, Anup Naha
    AAPS Pharmscitech, 2025
    The possibility of precisely regulating and targeting drug release with mesophase or Liquid crystal drug delivery systems has drawn much attention recently. This review offers a thorough investigation of liquid crystal drug delivery systems with an emphasis on their mesogenic architecture. It describes the various liquid crystal forms such as thermotropic and lyotropic liquid crystals and their applicability in advanced drug delivery. Liquid crystals are used as excellent carriers due to their distinctive characteristics, such as stimuli-responsive drug delivery and sustained release patterns. Comprehending the materials that form mesophase provides insight into their distinct physiochemical characteristics and their use in drug delivery. This review highlights the important role lyotropic and thermotropic liquid crystals play in drug delivery, underscoring their considerable potential. The transition of thermotropic liquid crystals from their conventional technological applications to drug delivery has been studied. Nonetheless, a few challenges still need to be addressed, including formulation strategy refinement, regulating release rates, maximising the loading of hydrophilic drugs, and storage stability. In the pharmaceutical field, addressing these issues will open the door to a revolutionary paradigm that will revolutionise therapeutic outcomes and improve patient care. Graphical Abstract
  • Microbial-Based Nanoparticle for Cancer Therapy: Opportunities and Challenges
    Kishor Dherange, Annamalai Rama, Hrithik Jadhav, Sweedal D’souza, Induja Govindan, Anjana A Kailas, Thamizharasan Annadurai, K.A. Abutwaibe, Anup Naha
    Drug Delivery Letters, 2025
  • Transformative solidification techniques for self-emulsifying drug delivery and its foresight in modern-day drug delivery
    Induja Govindan, Annamalai Rama, Anjana A. Kailas, Srinivas Hebbar, Anup Naha
    Journal of Applied Pharmaceutical Science, 2024
  • Drug delivery to the lymphatic system: The road less travelled
    Annamalai Rama, Induja Govindan, Anjana A. Kailas, Thamizharasan Annadurai, Shaila Angela Lewis, Sreedhara Ranganath Pai, A. Naha
    Journal of Applied Pharmaceutical Science, 2024
  • Design and assessment of in silico screened diosmin incorporated ultra-flexible topical lipid gel system for the treatment of varicose vein
    Akhilesh Dubey, Amitha Shetty, Chaithra R. Shetty, Namdev Dhas, Anup Naha, Pratika Bhandary, Srinivas Hebbar
    Journal of Applied Pharmaceutical Science, 2024
  • Development and evaluation of prevention bundle for neonatal healthcare-associated infections: an interventional study
    Usha Rani, Leslie E Lewis, Kiran Chawla, Anup Naha, Praveen Kumar
    F1000research, 2024
  • Enhancing radiation safety and efficiency in nuclear medicine through automated drug dispensing systems: A feasibility study with staff acceptance analysis
    Sanoop Chandran, Annamalai Rama, Induja Govindan, Anjana A. Kailas, Srinivas Hebbar, Anup Naha, Usha Rani
    Journal of Applied Pharmaceutical Science, 2024
  • Delivery of Nutraceutical Products in Sports
    Hrithik Dadasaheb Jadhav, Anjana A Kailas, Annamalai Rama, Induja Govindan, Thamizharasan Annadurai, Abutwaibe KA, Kishore Dherange, Sweedal D’Souza, Anup Naha
    Research Journal of Pharmacy and Technology, 2024
  • Job skill assessment of pharmacy students in South Karnataka: A cross-sectional study
    Shanthi Lysetty, Anup Naha, Usha Yogendra Nayak, Virendra S. Ligade, Bhavana B. Bhat, Usha Ran
    Journal of Applied Pharmaceutical Science, 2023
  • Advancing posaconazole quantification analysis with a new reverse-phase HPLC method in its bulk and marketed dosage form
    Annamalai Rama, Induja Govindan, Srinivas Hebbar, Abhishek Chaturvedi, Usha Rani, Anup Naha
    F1000research, 2023
  • The purview of doped nanoparticles: Insights into their biomedical applications
    Raghavendra Udaya Kumar Shenoy, Annamalai Rama, Induja Govindan, Anup Naha
    Opennano, 2022
  • Factorial design-based fabrication of biopolymer-functionalized Asiatic acid-embedded liposomes: in-vitro characterization and evaluation
    Namdev Dhas, Hosadurga Shantharam Preetha, Akhilesh Dubey, Gundawar Ravi, Induja Govindan, Annamalai Rama, Anup Naha, Srinivas Hebbar
    Journal of Applied Pharmaceutical Science, 2022
  • Evaluation of knowledge, attitude, and practice of medical and dental postgraduates toward reporting of adverse drug reactions in a teaching hospital, South India
    Gottipati Naga , Haritha, Anup Naha, Usha Rani, Annamalai Rama
    Journal of Applied Pharmaceutical Science, 2022
  • Nanosponges: Advancement in Nanotherapeutics
    Natasha Verma, Annamalai Rama, Adrija Jha, Bhautik Ladani, Induja Govindan, Sivakumar Kannan, Srinivas Hebbar, Anup Naha
    Research Journal of Pharmacy and Technology, 2022
  • BIOCONVERSION OF RECALCITRANT KERATIN RICH WASTES: A PRAGMATIC APPROACH TOWARDS SUSTAINABLE DEVELOPMENT
    Vidi Mehra, Swarnabh Chatterjee, Aravinda Pai, K. S. Chandrashekar, Anup Naha, Venkatesh Kamath B.
    Rasayan Journal of Chemistry, 2022
  • Design of Skill Enhancement Module for Pharmacy Students-Need of the Hour
    Shanthi Lysetty, Siva Kumar Kannan, Anup Naha, Usha Yogendra Nayak, Virendra Ligade
    Indian Journal of Pharmaceutical Education and Research, 2022
  • Virus-Like particles as a Novel Targeted Drug Delivery Platform for Biomedical Applications
    Annamalai Rama, Anuja Pai, Divya Rosa Barreto, Siva Kumar Kannan, Anup Naha
    Research Journal of Pharmacy and Technology, 2022
  • Preventable contributors to the neonatal healthcare-associated infections: A uni-center analytical study from South India.
    Usha Rani, Leslie E. Lewis, Kiran Chawla, Anup Naha
    F1000research, 2022
  • In-silico screening and molecular docking studies of active constituents of Withania somnifera to investigate its kinase inhibitory activities
    Journal of Pharmaceutical Negative Results, 2022
  • Cationic biopolymer decorated Asiatic Acid and Centella asiatica extract incorporated liposomes for treating early-stage Alzheimer's disease: An In-vitro and In-vivo investigation
    Akhilesh Dubey, Namdev Dhas, Anup Naha, Usha Rani, Ravi GS, Amitha Shetty, Chaithra R Shetty, Srinivas Hebbar
    F1000research, 2022
  • Temperature and pH-responsive nanogels as intelligent drug delivery systems: A comprehensive review
    Adrija Jha, Annamalai Rama, Bhautik Ladani, Natasha Verma, Sivakumar Kannan, Anup Naha
    Journal of Applied Pharmaceutical Science, 2021
  • A Descriptive Cross-sectional Study of Knowledge of Doping at Grassroot Level in India
    Sivakumar Kannan, Anup Naha, Robindra Ramnarine Singh, Punit Bansal, Vinod C Nayak, Sandeep Goud, Usha Rani
    Research Journal of Pharmacy and Technology, 2021
  • Lymphatic drug transport and associated drug delivery technologies: A comprehensive review
    Manjot S. Punjabi, Anup Naha, Disha Shetty, Usha Y. Nayak
    Current Pharmaceutical Design, 2021
  • Formulation and Evaluation of Self Emulsifying Drug Delivery System (SEDDS) of a Novel Pharmacokinetic Enhancer Cobicistat
    Latin American Journal of Pharmacy, 2021
  • EMERGING ROLES OF SPORTS PHARMACIST IN THE HEALTH MANAGEMENT OF ATHLETES
    Pharma Times, 2021
  • Role of dietary supplements in sports performance
    Sivakumar Kannan, Anup Naha, Robindra Ramnarine Singh, Punit Bansal, Vinod C. Nayak, Sandeep Goud, Usha Rani
    Research Journal of Pharmacy and Technology, 2020
  • Electrospun nanofibres and their biomedical applications
    Poornima D Adpekar, Annamalai Rama, U. Rani, A. Naha
    Research Journal of Pharmacy and Technology, 2020
  • Development, evaluation and optimization of solid self emulsifying drug delivery system (S-sedds) of lercanidipine hydrochloride
    Panyam Bhargavi, Anup Naha, Sivakumar Kannan, Annamalai Rama
    Research Journal of Pharmacy and Technology, 2020
  • Sports pharmacists: A noble evolving professional in Indian pharmaceutical arena
    Sivakumar Kannan, Anup Naha, Robindra Ramnarine Singh, Punit Bansal, Vinod C Nayak, Sandeep Goud
    Research Journal of Pharmacy and Technology, 2020
  • A Review on Novel Biochemical Mediator Triggered on Demand Drug Delivery System
    Journal of Global Pharma Technology, 2020
  • Development of solid self-emulsifying formulation for improving the solubility of albendazole
    Latin American Journal of Pharmacy, 2020
  • Formulation of polymeric nanoparticles of lercanidipine by two bottom down techniques optimized by design of experiment
    Alicia Menezes, Shanthi Lysetty, Anup Naha
    Materiale Plastice, 2020
  • Design of Experiments in Pharmaceutical Development
    Abhishek S. Dhoot, Gasper J. Fernandes, Anup Naha, Mahalaxmi Rathnanand, Lalit Kumar
    Pharmaceutical Chemistry Journal, 2019
  • A review on dietary supplements: Delivery systems, applications and regulations
    Akshay R Rao, Anup Naha, Sivakumar Kannan, Suhas B. S, Shubham Asagoankar
    Research Journal of Pharmacy and Technology, 2019
  • Oral bioavailability enhancement of glibenclamide by self-emulsifying drug delivery systems (SEDDS)
    Latin American Journal of Pharmacy, 2019
  • Compritol® 888 LIPID matrix via twin screw extruder
    Abishek Wadhwa, Vashish Mathura, Mahalaxmi Rathnanand, Anup Naha, Shaila Angela Lewis
    International Journal of Applied Pharmaceutics, 2019
  • Full factorial experimental design for development and validation of a RP-HPLC method for estimation of letrozole in nanoformulations
    Aswathi R. Hegde, Renuka S. Managuli, Anup Naha, Kunnatur B. Koteshwara, Meka Sreenivasa Reddy, Srinivas Mutalik
    Current Pharmaceutical Analysis, 2018
  • Cost analysis and utilization of mechanical ventilators in intensive care units of south India
    Pakistan Journal of Medical and Health Sciences, 2018
  • Nanocrystals: A newer technological advancement in drug delivery
    Neha Xalxo, Anup Naha, Abhishek Dhoot, Juhi Priya
    Research Journal of Pharmacy and Technology, 2018
  • Phase diagrams for three component mixtures in pharmaceuticals and its applications
    Abhishek Sunil Dhoot, Anup Naha, JuhiPriya JuhiPriya J, NehaXalxo NehaXalxo N
    Journal of Young Pharmacists, 2018
  • A review on polymeric nanoparticles: A promising novel drug delivery system
    Journal of Global Pharma Technology, 2018
  • Development of ritonavir solid lipid nanoparticles by Box Behnken design for intestinal lymphatic targeting
    Swapnil Kumar, Reema Narayan, Vasif Ahammed, Yogendra Nayak, Anup Naha, Usha Y. Nayak
    Journal of Drug Delivery Science and Technology, 2018
  • Formulation and evaluation of irbesartan nanosuspension for dissolution enhancement
    Mistry Khushboo, Kavya Naik, Vasanthi, Alicia Menezes, Anup Naha, K.B. Koteshwara, K. Girish Pai
    Research Journal of Pharmacy and Technology, 2017
  • Effect of adjunctive use of green tea dentifrice in periodontitis patients – A Randomized Controlled Pilot Study
    TS Hrishi, PP Kundapur, A Naha, BS Thomas, S Kamath, GS Bhat
    International Journal of Dental Hygiene, 2016
  • Novel economical technique for the formulation of fast dissolving tablet
    Research Journal of Pharmacy and Technology, 2012
  • Implementation of task based learning for overall development of pharmacy students
    Research Journal of Pharmacy and Technology, 2012
  • Design and development of multiparticulate drug delivery of metronidazole for targeted delivery to colon
    International Journal of Pharmacy and Technology, 2011
  • Preparation and physicochemical and preclinical evaluations of recrystallized celecoxib
    PDA Journal of Pharmaceutical Science and Technology, 2007
  • Preparation, in vitro, preclinical and clinical evaluations of once daily sustained release tablets of aceclofenac
    S. Mutalik, A. Naha, A. N. Usha, A. K. Ranjith, P. Musmade, K. Manoj, P. Anju, S. Prasanna
    Archives of Pharmacal Research, 2007

RECENT SCHOLAR PUBLICATIONS

  • Exploiting the role of milk extracellular vesicles: a comprehensive analysis on isolation methods, characterization, surface modifications, and their therapeutic applications
    MR Prabhu, D Upadhya, H Madhyastha, A Naha, H Perumalsamy, ...
    Journal of nanobiotechnology , 2026
    2026
  • A Study on Quality Assurance and Utilization of Equipment in the Radiology Department of a Tertiary Care Teaching Hospital
    P Arathi, A Naha, S Kumar, U Rani
    Hospital Topics 104 (1), 1-13 , 2026
    2026
  • A Green RP-HPLC Method for Quantification of Posaconazole in Bulk Drug and SNEDDS: Development, Validation, and Stability Assessment
    I Govindan, A Rama, AA Kailas, KA Abutwaibe, T Annadurai, U Rani, ...
    Journal of Applied Pharmaceutical Science, 22313354261427901 , 2026
    2026
  • Targeted Delivery of Quercetin to the Brain via a Modified Polymeric Nanocarrier
    P Bhadane, A Khairnar, K Pandya, A Naha, D Kumar, KA Abutwaibe, ...
    Macromolecular Bioscience 26 (1), e00503 , 2026
    2026
  • Thermotropic liquid crystals for precision drug delivery and diagnostics: Molecular design, characterization, and clinical translation
    AA Kailas, KA Abutwaibe, P Bhagavath, D Bhattacharjee, A Rama, ...
    Journal of Applied Pharmaceutical Science 16 (1), 029-045 , 2025
    2025
  • Density functional theory analysis of two fluorinated liquid crystalline materials: a comprehensive study
    K Garg, J Herman, A Naha, D Bhattacharjee
    Discover Applied Sciences 7 (11), 1315 , 2025
    2025
    Citations: 1
  • Structured engineering of self-emulsifying drug delivery systems (SEDDS) via 3D printing: Comprehensive review
    I Govindan, AA Kailas, KA Abutwaibe, T Annadurai, U Achar, A Naha, ...
    International Journal of Pharmaceutics: X, 100416 , 2025
    2025
    Citations: 3
  • High‐resolution simulation of the Bay of Bengal rain plume
    N Anup, PN Vinayachandran, DN Subramani
    Journal of Geophysical Research: Oceans 130 (8), e2025JC022676 , 2025
    2025
    Citations: 1
  • Subtidal variability of near-surface salinity in the Cochin estuary, southwest coast of India: Insights from year-long continuous observation
    IP Safin, V Vijith, R Sajeev, N Anup, S Vasudevan, NMI Shehsin, PK Saji, ...
    Journal of Marine Systems 250, 104086 , 2025
    2025
    Citations: 1
  • Impact of fluorine substitution on benzene ring in two fluorinated liquid crystal compounds: a comprehensive analysis using TG-DTA, FT-IR, UV, and PED techniques
    K Garg, A Chakraborty, M Żak, J Herman, A Naha, D Bhattacharjee
    Discover Applied Sciences 7 (5), 471 , 2025
    2025
    Citations: 7
  • Microbial-based nanoparticle for cancer therapy: opportunities and challenges
    K Dherange, A Rama, H Jadhav, S D’souza, I Govindan, AA Kailas, ...
    Drug Delivery Letters , 2025
    2025
    Citations: 1
  • Mesogenic architectures for advanced drug delivery: interrogating lyotropic and thermotropic liquid crystals
    I Govindan, A Paul, A Rama, AA Kailas, KA Abutwaibe, T Annadurai, ...
    AAPS PharmSciTech 26 (1), 6 , 2024
    2024
    Citations: 18
  • Enhancing radiation safety and efficiency in nuclear medicine through automated drug dispensing systems: A feasibility study with staff acceptance analysis
    S Chandran, A Rama, I Govindan, AA Kailas, S Hebbar, A Naha, U Rani
    Journal of Applied Pharmaceutical Science 14 (8), 061-069 , 2024
    2024
    Citations: 2
  • Transformative solidification techniques for self-emulsifying drug delivery and its foresight in modern-day drug delivery
    I Govindan, A Rama, AA Kailas, S Hebbar, A Naha
    Journal of Applied Pharmaceutical Science 14 (7), 001-013 , 2024
    2024
    Citations: 10
  • Drug delivery to the lymphatic system: The road less travelled
    A Rama, I Govindan, AA Kailas, T Annadurai, SA Lewis, SR Pai, A Naha
    Journal of Applied Pharmaceutical Science 14 (6), 001-010 , 2024
    2024
    Citations: 10
  • Development and evaluation of prevention bundle fo r neonatal healthcare-associated infections: an interventiona l study [version 2; peer review: 1 approved, 1 approved with
    U Rani, LE Lewis, K Chawla, A Naha, P Kumar
    2024
  • Development and evaluation of prevention bundle for neonatal healthcare-associated infections: an interventional study
    U Rani, LE Lewis, K Chawla, A Naha, P Kumar
    F1000Research 12, 687 , 2024
    2024
    Citations: 3
  • Design and assessment of in silico screened diosmin incorporated ultra-flexible topical lipid gel system for the treatment of varicose vein
    A Dubey, A Shetty, CR Shetty, N Dhas, A Naha, P Bhandary, S Hebbar
    Journal of Applied Pharmaceutical Science 14 (4), 143-154 , 2024
    2024
    Citations: 2
  • Observation of Nonseismic Sea level Oscillations at TsunamiTimescales (T< 2 hours) along the Indian Subcontinent
    B Rohith, S Sidharth, N Anup
    EGU24 , 2024
    2024
  • Volcanic eruption triggers a rare meteotsunami in the Indian Ocean
    N Anup, B Rohith, V Vijith, L Rose, P Sreeraj, A Sabu, KS Krishnamohan, ...
    Geophysical Research Letters 51 (2), e2023GL108036 , 2024
    2024
    Citations: 7

MOST CITED SCHOLAR PUBLICATIONS

  • Preparation, In vitro , preclinical and clinical evaluations of once daily sustained release tablets of aceclofenac
    S Mutalik, A Naha, AN Usha, AK Ranjith, P Musmade, K Manoj, P Anju, ...
    Archives of pharmacal research 30 (2), 222-234 , 2007
    2007
    Citations: 140
  • Effect of adjunctive use of green tea dentifrice in periodontitis patients–A Randomized Controlled Pilot Study
    TS Hrishi, PP Kundapur, A Naha, BS Thomas, S Kamath, GS Bhat
    International journal of dental hygiene 14 (3), 178-183 , 2016
    2016
    Citations: 102
  • Design of experiments in pharmaceutical development
    AS Dhoot, GJ Fernandes, A Naha, M Rathnanand, L Kumar
    Pharmaceutical Chemistry Journal 53 (8), 730-735 , 2019
    2019
    Citations: 64
  • The purview of doped nanoparticles: Insights into their biomedical applications
    RUK Shenoy, A Rama, I Govindan, A Naha
    OpenNano 8, 100070 , 2022
    2022
    Citations: 62
  • Development of ritonavir solid lipid nanoparticles by Box Behnken design for intestinal lymphatic targeting
    S Kumar, R Narayan, V Ahammed, Y Nayak, A Naha, UY Nayak
    Journal of Drug Delivery Science and Technology 44, 181-189 , 2018
    2018
    Citations: 60
  • Nanosuspensions: a novel drug delivery approach
    KB Koteshwara, MS Reddy, A Naha, M Nampoothiri
    IJRAP 2 (1), 162-165 , 2011
    2011
    Citations: 38
  • Colon targeted drug delivery system: A review
    KB Koteshwara, A Naha, M Nampoothiri
    International Journal of Research in Ayurveda & Pharmacy 2 (1), 60-65 , 2011
    2011
    Citations: 38
  • Temperature and pH-responsive nanogels as intelligent drug delivery systems: A comprehensive review
    A Jha, A Rama, B Ladani, N Verma, S Kannan, A Naha
    Journal of Applied Pharmaceutical Science 11 (12), 001-016 , 2021
    2021
    Citations: 36
  • Phase diagrams for three component mixtures in pharmaceuticals and its applications
    AS Dhoot, A Naha, J Priya, N Xalxo
    Journal of Young Pharmacists 10 (2), 132 , 2018
    2018
    Citations: 31
  • Mesogenic architectures for advanced drug delivery: interrogating lyotropic and thermotropic liquid crystals
    I Govindan, A Paul, A Rama, AA Kailas, KA Abutwaibe, T Annadurai, ...
    AAPS PharmSciTech 26 (1), 6 , 2024
    2024
    Citations: 18
  • Lymphatic drug transport and associated drug delivery technologies: a comprehensive review
    MS Punjabi, A Naha, D Shetty, UY Nayak
    Current Pharmaceutical Design 27 (17), 1992-1998 , 2021
    2021
    Citations: 17
  • A review on polymeric nanoparticles: a promising novel drug delivery system
    A Naha, J Priya, A Dhoot, N Xalxo
    J Glob Pharm Technol 10, 10-7 , 2018
    2018
    Citations: 16
  • Full factorial experimental design for development and validation of a RP-HPLC method for estimation of letrozole in nanoformulations
    AR Hegde, RS Managuli, A Naha, KB Koteshwara, MS Reddy, S Mutalik
    Current Pharmaceutical Analysis 14 (3), 320-330 , 2018
    2018
    Citations: 15
  • Cationic biopolymer decorated Asiatic Acid and Centella asiatica extract incorporated liposomes for treating early-stage Alzheimer’s disease: An In-vitro and In-vivo investigation
    A Dubey, N Dhas, A Naha, U Rani, R Gs, A Shetty, CR Shetty, S Hebbar
    F1000Research 11, 1535 , 2022
    2022
    Citations: 13
  • Formulation and evaluation of irbesartan nanosuspension for dissolution enhancement
    M Khushboo, K Naik, A Menezes, A Naha, KB Koteshwara, KG Pai
    Research Journal of Pharmacy and Technology 10 (9), 3043-3048 , 2017
    2017
    Citations: 13
  • Transformative solidification techniques for self-emulsifying drug delivery and its foresight in modern-day drug delivery
    I Govindan, A Rama, AA Kailas, S Hebbar, A Naha
    Journal of Applied Pharmaceutical Science 14 (7), 001-013 , 2024
    2024
    Citations: 10
  • Drug delivery to the lymphatic system: The road less travelled
    A Rama, I Govindan, AA Kailas, T Annadurai, SA Lewis, SR Pai, A Naha
    Journal of Applied Pharmaceutical Science 14 (6), 001-010 , 2024
    2024
    Citations: 10
  • Advancing posaconazole quantification analysis with a new reverse-phase HPLC method in its bulk and marketed dosage form
    A Rama, I Govindan, S Hebbar, A Chaturvedi, U Rani, A Naha
    F1000Research 12, 468 , 2023
    2023
    Citations: 10
  • Role of dietary supplements in sports performance
    S Kannan, A Naha, RR Singh, P Bansal, VC Nayak, S Goud, U Rani
    Research Journal of Pharmacy and Technology 13 (12), 6259-6265 , 2020
    2020
    Citations: 10
  • Quasi-biweekly oscillation in sea level along the western Bay of Bengal
    N Anup, V Vijith, AK Jithin, B Rohith, P Amol, PA Francis
    Continental Shelf Research 231, 104594 , 2021
    2021
    Citations: 9