Meenalshi kanwar chauhan

Scopus Publications

Molecular Nutrition in Wound Healing
Anuj Mittal, Saurabh Choudhary, Anshul, Ashwani, Dalapathi Gugulothu, et al.
Therapeutics and Molecular Nutrition, 2026
Biomimetic 3D-Printed Adaptive Hydrogel Bioadhesives Featuring Superior Infection Resistance for Challenging Tissue Adhesion, Hemostasis, and Healthcare
Qi Wu, Meenakshi Chauhan, Bassma Khamaisi, Eid Nassar‐Marjiya, Shady Farah
Advanced Materials, 2025
Conventional suturing and stapling cause additional trauma, pain, and cost for patients. As alternatives, existing bioadhesives suffer from imprecise fabrication, limited wet tissue adhesion, and insufficient biological functionalities for effective wound management. This work proposes biomimetic hydrogel bioadhesives composed of modified natural tannic acid (TA), hyperbranched polylysine (HPL), and acrylic acid (AA), abbreviated PTLAs, to offer solutions for tissue adhesion under challenging environments (underwater, body fluids, cold, pressure), and for enhanced healthcare. These PTLAs are fabricated via 3D printing, enabling the precise and controlled production of bioadhesives that are customized in a personalized manner with great reproducibility. Inspired by molluscs, developed PTLAs exhibit robust wet and underwater tissue adhesion, outperforming commercial and many recently reported bioadhesives. Ex vivo lamb and in vivo rat models demonstrate ultrafast (5 s) and efficient sealing and hemostasis. Exceptional freeze resistance and pressure resistance further expand their applicability to extreme environments. Meanwhile, coupled with superior infection resistance, PTLAs ensure enhanced wound healthcare while sealing and hemostasis. Further, their self‐gelling feature supports dry powder adhesion/sealing applications, practical packaging, and long‐term storage. Overall, adaptive tissue‐like PTLAs present transformative potential as bio‐tapes, bio‐bandages, bio‐sealants, bio‐carriers, etc., paving the way for next‐generation bioadhesives design and enhanced healthcare solutions.
New Physical Methods for Characterization of Freeze-Dried Goods
Monika Targhotra, Nidhi Bhatt, Meenakshi Kanwar Chauhan
Freeze Drying Technology in Pharmaceutical and Biomedical Product Development Impact Progress and Challenges of Lyophilization, 2025
Liquid and Polydisperse Systems: Emulsions
K. Shubham, B. Behera, Meenakshi K. Chauhan
Advances in Pharmaceutical Product Development, 2025
Advancements in CAR-T Therapy: A Comprehensive Review
Aastha Tanwar, Monika Targhotra, Meenakshi Kanwar Chauhan
Current Cancer Therapy Reviews, 2025
Chimeric Antigen Receptor T-cell (CAR-T) therapy has emerged as a ground-breaking approach in cancer treatment, offering new hope to patients with refractory or relapsed malignancies. By genetically modifying T lymphocytes, this potent method allows for the targeted eradication of infectious cells. The efficient production of CAR-T cells is essential for the effective use of these treatments to treat malignancies, as it affects not just the product's efficacy as well as safety but also its general availability to patients who require it. This article's primary goal is to provide a comprehensive overview of CAR-T therapy, encompassing its historical evolution, mechanistic insights, clinical applications, challenges, and future directions. By synthesizing existing literature and realworld evidence, this review seeks to elucidate the significance of CAR-T therapy in the landscape of cancer treatment and its potential to redefine the standard of care for patients with refractory or relapsed malignancies. The methodology involved a comprehensive literature search conducted using various databases, including PubMed, Google Scholar, and clinical trial registries such as Clinical- Trials.gov. The search strategy incorporated a combination of relevant keywords and Medical Subject Headings (MeSH) terms, including but not limited to "CAR-T therapy," "chimeric antigen receptor T-cell therapy," "cancer immunotherapy," "clinical trials," "pharmaceutical companies," "regulatory approvals," "pipeline molecules," and "cancer types." Boolean operators (AND, OR) were utilized to refine the search and capture relevant articles and studies. In addition to database searches, manual screening of reference lists from relevant review articles and primary studies was performed to identify additional relevant publications. The inclusion criteria encompassed original research articles, clinical trials, systematic reviews, meta-analyses, and regulatory documents related to CAR-T cell therapy and its applications in cancer treatment and the review included studies published in English between January 2010 and March 2024. Exclusion criteria comprised studies not relevant to the scope of the review, such as those focusing on non-CAR-T cell therapies or non-cancer-related topics. This review underscores the transformative potential of CAR-T therapy in cancer treatment, highlighting its efficacy, safety, and clinical relevance across various malignancies. By synthesizing findings from preclinical studies, clinical trials, and real-world data from patients, CAR-T therapy has consistently exhibited remarkable therapeutic outcomes. These include high response rates, durable remissions, and significant improvements in survival outcomes among patients with refractory or relapsed cancers. Additionally, the inclusion of practical research with big data from real patients further supports the robustness and applicability of CAR-T therapy in clinical practice. In conclusion, CAR-T therapy represents a paradigm shift in cancer treatment, offering new avenues for personalized and precisiondriven oncology. By addressing current gaps, optimizing treatment protocols, and exploring novel strategies, CAR-T therapy holds immense promise in reshaping the landscape of oncology and providing hope to patients with advanced malignancies.
Injectable, in-situ forming, tunable, biocompatible gelatin hydrogels for biomedical applications
Meenakshi Chauhan, Purandhi Roopmani, Jayakumar Rajendran, Kumar Pranav Narayan, Jyotsnendu Giri
International Journal of Biological Macromolecules, 2025
Physicochemical stability of lipid based nanocarriers in aerosol formulation
Pankaj Kumar Sharma, Monika Targhotra, Akanksha Sharma, Nidhi Bhatt, Meenakshi Kanwar Chauhan, et al.
Lipids in Pulmonary Drug Delivery, 2025
Tricompartmental Microcarriers with Controlled Release for Efficient Management of Parkinson’s Disease
Nidhi Gupta, Pankaj Kumar Sharma, Shreyash Santosh Yadav, Meenakshi Chauhan, Ashok Kumar Datusalia, et al.
ACS Biomaterials Science and Engineering, 2024
Parkinson's is a progressive neurodegenerative disease of the nervous system. It has no cure, but its symptoms can be managed by supplying dopamine artificially to the brain.This work aims to engineer tricompartmental polymeric microcarriers by electrohydrodynamic cojetting technique to encapsulate three PD (Parkinson's disease) drugs incorporated with high encapsulation efficiency (∼100%) in a single carrier at a fixed drug ratio of 4:1:8 (Levodopa (LD): Carbidopa(CD): Entacapone (ENT)). Upon oral administration, the drug ratio needs to be maintained during subsequent release from microparticles to enhance the bioavailability of primary drug LD. This presents a notable challenge, as the three drugs vary in their aqueous solubility (LD > CD > ENT). The equilibrium of therapeutic release was achieved using a combination of FDA-approved polymers (PLA, PLGA, PCL, and PEG) and the disc shape of particles. In vitro studies demonstrated the simultaneous release of all the three therapeutics in a sustained and controlled manner. Additionally, pharmacodynamics and pharmacokinetics studies in Parkinson's disease rats induced by rotenone showed a remarkable improvement in PD conditions for the microparticles-fed rats, thereby showing a great promise toward efficient management of PD.
Preparation and In vitro release of Isoniazid and Rifampicin loaded nanoparticles
Nanomedicine Journal, 2024
Overcoming multidrug resistance by reversan and exterminating glioblastoma and glioblastoma stem cells by delivering drug-loaded nanostructure hybrid lipid capsules (nHLCs)
Uzma Hasan, Meenakshi Chauhan, Suparna Mercy Basu, Jayakumar R., Jyotsnendu Giri
Drug Delivery and Translational Research, 2024
Role of Amphotericin B in the Treatment of Mucormycosis
Alisha Sachdeva, Monika Targhotra, Meenakshi Kanwar Chauhan, Monica Chopra
Current Pharmaceutical Design, 2024
Exploring the Efficacy of Traditional Herbs in Combating COVID-19: A Comprehensive Review
Anil Sao, Tulsidas Nimbekar, Garla Venkateswarlu, Mohit Mishra, Aditya Kate, et al.
Coronaviruses, 2024
pH-Responsive Polypropylene Sulfide Magnetic Nanocarrier-Mediated Chemo-Hyperthermia Kills Breast Cancer Stem Cells by Long-Term Reversal of Multidrug Resistance and Chemotherapy Resensitization
Suparna Mercy Basu, Meenakshi Chauhan, Jyotsnendu Giri
ACS Applied Materials and Interfaces, 2023
Effect of Propranolol Prophylaxis on Headache Frequency in Children with Migraine Without Aura: A Randomized, Double-Blind, Placebo-Controlled Trial
D. Keerthana, Devendra Mishra, Meenakshi Kanwar Chauhan, Monica Juneja
Indian Journal of Pediatrics, 2023
Swift and Precise Determination of Rifampicin by RP-HPLC Technology Development in Pharmaceuticals
Mohd. Aqil, Mamta Bishnoi, Meenakshi Kanwar Chauhan
Iranian Journal of Science, 2023
Biomaterial-based platforms for modulating immune components against cancer and cancer stem cells
Nimeet Desai, Uzma Hasan, Jeyashree K, Rajesh Mani, Meenakshi Chauhan, et al.
Acta Biomaterialia, 2023
Design and synthesis of photostable triphenylamine based neutral AIE nano luminogens: specific and long-term tracking of mitochondria in cells
Kathirvelan Devarajan, Mayakrishnan Sivakalai, Suparna Mercy Basu, Chinmoy Biswas, Meenakshi Chauhan, et al.
Biomaterials Science, 2023
Artificial Intelligence for Computer-Aided Drug Discovery
Aditya Kate, Ekkita Seth, Ananya Singh, Chandrashekhar Mahadeo Chakole, Meenakshi Kanwar Chauhan, et al.
Drug Research, 2023
Ultrashort Peptide-Based Hydrogel for the Healing of Critical Bone Defects in Rabbits (ACS Appl. Mater. Interfaces (2022) 14:48 (54111−54126) DOI: 10.1021/acsami.2c18733)
Nitin Yadav, Utkarsh Kumar, Purandhi Roopmani, Uma Maheswari Krishnan, Swaminathan Sethuraman, et al.
ACS Applied Materials and Interfaces, 2023
Fabrication, characterization and efficacy evaluation of natural gum-based bioactive haemostatic gauzes with antibacterial properties
Himanshu Kushwah, Nidhi Sandal, Meenakshi Chauhan, Gaurav Mittal
Journal of Biomaterials Applications, 2023
Polypropylene sulphide coating on magnetic nanoparticles as a novel platform for excellent biocompatible, stimuli-responsive smart magnetic nanocarriers for cancer therapeutics
Meenakshi Chauhan, Suparna Mercy Basu, Mohd Qasim, Jyotsnendu Giri
Nanoscale, 2023
Multifunctional nanocomposites for blood cancer
Monika Targhotra, Meenakshi Kanwar Chauhan
Multifunctional Nanocomposites for Targeted Drug Delivery in Cancer Therapy, 2023
Ultrashort Peptide-Based Hydrogel for the Healing of Critical Bone Defects in Rabbits
Nitin Yadav, Utkarsh Kumar, Purandhi Roopmani, Uma Maheswari Krishnan, Swaminathan Sethuraman, et al.
ACS Applied Materials and Interfaces, 2022
Quantitative evaluation of Chlorella vulgaris for removal of toxic metals from body
Mahendra Yadav, Vivek Kumar, Nidhi Sandal, Meenakshi Kanwar Chauhan
Journal of Applied Phycology, 2022
An approach towards safe and sustainable use of the green alga Chlorella for removal of radionuclides and heavy metal ions
Mahendra Yadav, Komal Rani, Nidhi Sandal, Meenakshi Kanwar Chauhan
Journal of Applied Phycology, 2022

RECENT SCHOLAR PUBLICATIONS

Molecular Nutrition in Wound Healing
A Mittal, S Choudhary, Anshul, Ashwani, D Gugulothu, MK Chauhan
Therapeutics and Molecular Nutrition, 211-246 , 2026
2026
Advancements in CAR-T Therapy: A Comprehensive Review
A Tanwar, M Targhotra, MK Chauhan
Current Cancer Therapy Reviews 21 (4), 433-442 , 2025
2025
New Physical Methods for Characterization of Freeze-Dried Goods
M Targhotra, N Bhatt, MK Chauhan
Freeze-drying Technology in Pharmaceutical and Biomedical Product … , 2025
2025
Liquid and Polydisperse Systems: Emulsions
K Shubham, B Behera, MK Chauhan
Advances in Pharmaceutical Product Development, 219-243 , 2025
2025
Citations: 1
Physicochemical stability of lipid based nanocarriers in aerosol formulation
PK Sharma, M Targhotra, A Sharma, N Bhatt, MK Chauhan, Y Sultana
Lipids in Pulmonary Drug Delivery, 353-369 , 2025
2025
Preparation and In vitro release of Isoniazid and Rifampicin loaded nanoparticles.
M Targhotra, MK Chauhan
Nanomedicine Journal 11 (3) , 2024
2024
Citations: 2
Exploring the Efficacy of Traditional Herbs in Combating COVID-19: A Comprehensive Review
A Sao, T Nimbekar, G Venkateswarlu, M Mishra, A Kate, MK Chauhan, ...
Coronaviruses 5 (2), 8-21 , 2024
2024
Citations: 3
Tricompartmental Microcarriers with Controlled Release for Efficient Management of Parkinson’s Disease
N Gupta, P Sharma, SS Yadav, MK Chauhan, AK Datusalia, S Saha
ACS Biomaterials Science and Engineering 10 (8), 5039-5056 , 2024
2024
Citations: 7
Role of Amphotericin B in the Treatment of Mucormycosis
A Sachdeva, M Targhotra, MK Chauhan*, M Chopra
Current Pharmaceutical Design , 2024
2024
Citations: 2
Multifunctional nanocomposites for blood cancer
M Targhotra, MK Chauhan
Multifunctional Nanocomposites for Targeted Drug Delivery in Cancer Therapy … , 2024
2024
Citations: 2
Artificial Intelligence for Computer-Aided Drug Discovery
A Kate, E Seth, A Singh, CM Chakole, MK Chauhan, RK Singh, ...
Drug research 73 (07), 369-377 , 2023
2023
Citations: 16
Effect of propranolol prophylaxis on headache frequency in children with migraine without aura: A randomized, double-blind, placebo-controlled trial
D Keerthana, D Mishra, MK Chauhan, M Juneja
Indian Journal of Pediatrics 90 (9), 880-885 , 2023
2023
Citations: 8
Swift and Precise Determination of Rifampicin by RP-HPLC Technology Development in Pharmaceuticals
M Aqil, M Bishnoi, MK Chauhan
Iranian Journal of Science 47 (4), 1137-1144 , 2023
2023
Citations: 6
Manufacturing Process of Nanoparticles
MK Chauhan, A Sachdeva, L Ansari, D Gugulothu
Pharmaceutical Process Engineering and Scale-up Principles, 151-172 , 2023
2023
Citations: 5
Correction: Artificial Intelligence for Computer-Aided Drug Discovery
A Kate, E Seth, A Singh, CM Chakole, MK Chauhan, RK Singh, ...
Drug Research 73 (07), e2-e2 , 2023
2023
Photothermal Therapy for Cancer Treatment
S Sharma, S Batra, MK Chauhan, V Kumar
Targeted Cancer Therapy in Biomedical Engineering, 755-780 , 2023
2023
Citations: 12
Theranostic Approaches for Diagnosis and Treatment of Cancer: An Update
R Ali, F Ahmed, MK Chauhan
Targeted Cancer Therapy in Biomedical Engineering, 631-662 , 2023
2023
Citations: 1
Biomaterial-Based Delivery Systems for Chemotherapeutics
D Gugulothu, D Dhawan, A Sachdeva, Deepali, MK Chauhan
Targeted cancer therapy in biomedical engineering, 105-178 , 2023
2023
Citations: 7
Nanotechnology-Tailored Drops of Brinzolamide and Curcumin for Glaucoma: Combined Attribution of Neuroprotection and Improved Oculo-Antihypertensive Effect.
CM Chakole, MK Chauhan
Current Trends in Biotechnology & Pharmacy 17 , 2023
2023
Fabrication, characterization and efficacy evaluation of natural gum-based bioactive haemostatic gauzes with antibacterial properties
H Kushwah, N Sandal, M Chauhan, G Mittal
Journal of Biomaterials Applications 37 (8), 1409-1422 , 2023
2023
Citations: 8

MOST CITED SCHOLAR PUBLICATIONS

Natural gums and modified natural gums as sustained-release carriers
TR Bhardwaj, M Kanwar, R Lal, A Gupta
Drug development and industrial pharmacy 26 (10), 1025-1038 , 2000
2000
Citations: 641
Ocular preparations: the formulation approach
I Pal Kaur, M Kanwar
Drug development and industrial pharmacy 28 (5), 473-493 , 2002
2002
Citations: 444
Formulation and evaluation of ophthalmic preparations of acetazolamide
IP Kaur, M Singh, M Kanwar
International journal of pharmaceutics 199 (2), 119-127 , 2000
2000
Citations: 187
Novel carbopol-based transfersomal gel of 5-fluorouracil for skin cancer treatment: in vitro characterization and in vivo study
MA Khan, J Pandit, Y Sultana, S Sultana, A Ali, M Aqil, M Chauhan
Drug delivery 22 (6), 795-802 , 2015
2015
Citations: 168
Short to ultrashort peptide-based hydrogels as platform for biomedical application
N Yadav, MK Chauhan, VS Chauhan
Biomaterials Science 8 (5), 84-100 , 2019
2019
Citations: 139
Treatment and management strategies of onychomycosis
R Aggarwal, M Targhotra, B Kumar, PK Sahoo, MK Chauhan
Journal de Mycologie Médicale, 100949 , 2020
2020
Citations: 121
Diabetes and cardiovascular disease: inter-relation of risk factors and treatment
A Sharma, S Mittal, R Aggarwal, MK Chauhan
Future Journal of Pharmaceutical Sciences 6, 1-19 , 2020
2020
Citations: 120
Intra-articular delivery of genipin cross-linked chitosan microspheres of flurbiprofen: preparation, characterization, in vitro and in vivo studies
J Kawadkar, MK Chauhan
European journal of Pharmaceutics and Biopharmaceutics 81 (3), 563-572 , 2012
2012
Citations: 94
Optimization and characterization of rivastigmine nanolipid carrier loaded transdermal patches for the treatment of dementia
MK Chauhan, PK Sharma
Chemistry and physics of lipids 224, 104794 , 2019
2019
Citations: 92
Niosomes as vesicular carriers for delivery of proteins and biologicals
S Shilpa, BP Srinivasan, M Chauhan
International Journal of Drug Delivery 3 (1) , 2011
2011
Citations: 82
Formulation, characterization and in vitro–in vivo evaluation of flurbiprofen-loaded nanostructured lipid carriers for transdermal delivery
J Kawadkar, A Pathak, R Kishore, MK Chauhan
Drug development and industrial pharmacy 39 (4), 569-578 , 2013
2013
Citations: 70
Ethosomes as vesicular carrier for enhanced transdermal delivery of Ketoconazole-Formulation and Evaluation
A Sheer, M Chauhan
IJPI’s Journal of Pharmaceutics and Cosmetology 1 (3), 1-14 , 2011
2011
Citations: 57
Span-60 niosomal oral suspension of fluconazole: formulation and in vitro evaluation
S Sandeep, K, M Chauhan, K, A Kumar
Asian Journal of Pharmaceutical Research and Health Care 1 (2), 142-56 , 2009
2009
Citations: 55
Bilosome: A bile salt based novel carrier system gaining interest in pharmaceutical research
T Rajput, MK Chauhan
Journal of Drug Delivery and Therapeutics 7 (5), 4-16 , 2017
2017
Citations: 53
Onychomycosis: Novel strategies for treatment
R Aggarwal, M Targhotra, PK Sahoo, MK Chauhan
Journal of Drug Delivery Science and Technology 57, 101774 , 2020
2020
Citations: 50
Gel containing ethosomal vesicles for transdermal delivery of aceclofenac
AK Garg, LM Negi, M Chauhan
International Journal of Pharmacy and Pharmaceutical Sciences 2 (2), 102-108 , 2010
2010
Citations: 48
Bioavailability Enhancement of Polymyxin B with novel drug delivery: Development and Optimization using Quality-by-Design Approach
MK Chauhan, N Bhatt
Journal of Pharmaceutical Sciences 108 (4), 1521-28 , 2019
2019
Citations: 40
Extended levobunolol release from Eudragit nanoparticle-laden contact lenses for glaucoma therapy
N Kumar, R Aggarwal, MK Chauhan
Future Journal of Pharmaceutical Sciences 6, 1-14 , 2020
2020
Citations: 38
Nanobiotechnology: application of nanotechnology in diagnosis, drug discovery and drug development
J Kawadkar, MK Chauhan, M Maharana
Asian J Pharm Clin Res 4, 23-25 , 2011
2011
Citations: 35
Formulation and evaluation of flurbiprofen-loaded genipin cross-linked gelatin microspheres for intra-articular delivery
J Kawadkar, R Jain, R Kishore, A Pathak, MK Chauhan
Journal of drug targeting 21 (2), 200-210 , 2013
2013
Citations: 34

Meenalshi kanwar chauhan

RESEARCH INTERESTS

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

MOST CITED SCHOLAR PUBLICATIONS