MicroRNA-32 Suppression: Its Effects on Prostate Cancer Cells' Capability to Proliferate and Migrate Farah A. Al-Marzook, Duha Maithem Hassan, Maha Waleed Alghazal, Rana Abd Alameer Kadheem, Abduladheem Turki Jalil, et al. Drug Research, 2023 Introduction This paper sought to scrutinize the role of microRNA-32 (miR-32) on the growth and migration as well as on the expression of metastatic genes in PC3 cells of prostate cancer in vitro. Methods Subsequent transfection of cells with miR-32 mimics, miR-32 inhibitor, negative control (NC), cell proliferation using MTT, and apoptosis by ELISA were performed. Furthermore, qRT-PCR was directed to measure the expression levels of matrix metalloproteinase 2 (MMP2) and vascular endothelial growth factors (VEGF) as metastatic and angiogenesis genes in the progression of PC3. Results miR-32 was overexpressed in PC3 cells compared to normal cells (P<0.001). Down-regulation of miR-32 obstructs in vitro proliferation and migration while intensifying the apoptosis rate in PC3 cells. Also, we found that miR-32 negatively modulates the expression of VEGF and MMP2 in PC3 cells. Conclusion These results indicate that the suppression of miR-32 might offer an auxiliary treatment procedure for addressing the invasion, progression, and metastasis in PCa patients by improving cell apoptosis.
A Systematic Review of case Reports of Neoplastic Changes in Epithelial lining of Dentigerous Cysts AH Murad, MS Merza, MW Alghazali Future Dental Research 3 (2), 49-56 , 2025 2025
Evaluation of Gingegel Gel for the Treatment of Gingivitis: A randomized clinical trial AH Alwan, MW Alghazali, AA Hussain Journal of Emergency Medicine, Trauma & Acute Care 2023 (3), 9 , 2023 2023 Citations: 2
Efficacy of Diode Laser 940 nm in Dentine Hypersensitivity reduction: a clinical trial MW Alghazali, FARM Al-Bazaz, MFJ Al-azzawi, SA Saadun Journal of Emergency Medicine, Trauma & Acute Care 2023 (3), 6 , 2023 2023 Citations: 3
Dental environment stress among Iraqi students: A qualitative study BF Alanbari, MJAL Juboori, MW Alghazali Journal of Emergency Medicine, Trauma & Acute Care 2023 (3), 3 , 2023 2023 Citations: 3
The role of Ferroptosis in the Pathogenesis of Osteoarthritis HRAK Al-Hetty, SJ Abdulameer, MW Alghazali, FS Sheri, MM Saleh, ... The Journal of Membrane Biology 256 (3), 223-228 , 2023 2023 Citations: 43
Nanomaterials for combination cancer photothermal therapy HRAK Al-Hetty, AT Jalil, MW Alghazali, H fadel, OS Ahmed, M Abosaooda, ... Emergent Materials 6 (2), 425-438 , 2023 2023 Citations: 11
MicroRNA-32 Suppression: Its Effects on Prostate Cancer Cells' Capability to Proliferate and Migrate MM Al-Marzook, F.A. , Hassan, D.M. , Alghazal, M.W. , ... Jalil, A.T. , Saleh Drug Research 73, 170–174 , 2023 2023 Citations: 7
Covid-19 Vaccin Hesitancy among Iraqi Dentists AHA Madiha Fouad Jameel Al-azzawi, Maha Waleed Alghazali, Marwah M. Hareeja ... Journal of Medicinal and Chemical Sciences 6 (2), 424-432 , 2023 2023 Citations: 3
Archive of SID. ir AH Alwan, BF Alanbari, MW Alghazali, AA Hussain, FARM Al_Bazaz 2023
Effect of CO2 laser and selected nanoparticles on the microhardness of human dental enamel in vitro study F Al Bazaz, N Radhi, KA Hubeatir, MW Alghazali J Med Chem Sci 6 (7), 1487-1497 , 2023 2023 Citations: 13
Evaluation of the Effect of Patient Related Factors on Periodontal Condition in a Sample of Iraqi Population: A Retrospective Study FAR Alwan, A.H., Alanbari, B.F., Alghazali, M.W., Hussain, A.A., Mahmood Al ... Journal of Medicinal and Chemical Sciences 6 (5), 1010–1031 , 2023 2023 Citations: 2
Non-coding RNAs, another side of immune regulation during triple-negative breast cancer MW Alghazali, HRAK Al-Hetty, ZMM Ali, MM Saleh, AAJ Suleiman, ... Pathology-Research and Practice 239, 154132 , 2022 2022 Citations: 11
Solubility Enhancement of Meloxicam by Binary and Ternary Solid Dispersion MW Hareeja, M.M. , Abbas, I.K. , Madiha, F. , Alghazali Journal of Pharmaceutical Negative Resultsthis link is disabled 13 (4), 116–124 , 2022 2022
Contributions and therapeutic potential of tumor-derived microRNAs containing exosomes to cancer progression ATJ Hussein Riyadh Abdul Kareem Al-Hetty, Sada Jasim Abdulameer, Maha Waleed ... Gene Reports 29, 101672 , 2022 2022 Citations: 2
Comparative study of oral soft tissue operations using a laser vs. a scalpel AAH Maha Waleed Alghazali, Rasha Abduljaleel Althabit, Abdulkareem Hussain ... NeuroQuantology 20 (5), 488-491 , 2022 2022 Citations: 2
Changes in oral health attitude and behavior of undergraduate Iraqi dental students AHA Madiha Fouad Jameel Al-azzawi, Maha Waleed Alghazali, Rasha Abduljaleel ... Bulletin of National Institute of Health Sciences 140 (1), 1407-1419 , 2022 2022
Solubility enhancement of meloxicam by binary and ternary solid dispersion MM Hareeja, IK Abbas, F Madiha, MW Alghazali Journal of Pharmaceutical Negative Results¦ Volume 13 (4), 116 , 2022 2022 Citations: 2
Gingivectomy by Diode Laser and Conventional Method ( A Comparative Study) MWA Abdulkareem Hussain Alwan, Rasha Abduljaleel Althabit IOSR Journal of Dental and Medical Sciences 20 (7), 56-61 , 2021 2021 Citations: 4
Abstracts from the 4 th Congress of the World Federation for Laser DentistryEuropean DivisionJuly 11–12, 2013Brussels, Belgium VGA Suter, HJ Altermatt, T Dietrich, PA Reichart, MM Bornstein, U Myron, ... Photomedicine and Laser Surgery 31 (12), 630-645 , 2013 2013
Comparative Histological Study of Dentinopulpal Responses in Class I Cavity Treated by Er: YAG Laser and Conventional Cavity Preparations: An in Vivo Trial MW Al-Gazali, AS Mahmood, LM Al-Azzawi, RK Jarjess Iraqi Journal of Laser 9 (B), 33-41 , 2010 2010 Citations: 2
MOST CITED SCHOLAR PUBLICATIONS
The role of Ferroptosis in the Pathogenesis of Osteoarthritis HRAK Al-Hetty, SJ Abdulameer, MW Alghazali, FS Sheri, MM Saleh, ... The Journal of Membrane Biology 256 (3), 223-228 , 2023 2023 Citations: 43
Effect of CO2 laser and selected nanoparticles on the microhardness of human dental enamel in vitro study F Al Bazaz, N Radhi, KA Hubeatir, MW Alghazali J Med Chem Sci 6 (7), 1487-1497 , 2023 2023 Citations: 13
Nanomaterials for combination cancer photothermal therapy HRAK Al-Hetty, AT Jalil, MW Alghazali, H fadel, OS Ahmed, M Abosaooda, ... Emergent Materials 6 (2), 425-438 , 2023 2023 Citations: 11
Non-coding RNAs, another side of immune regulation during triple-negative breast cancer MW Alghazali, HRAK Al-Hetty, ZMM Ali, MM Saleh, AAJ Suleiman, ... Pathology-Research and Practice 239, 154132 , 2022 2022 Citations: 11
MicroRNA-32 Suppression: Its Effects on Prostate Cancer Cells' Capability to Proliferate and Migrate MM Al-Marzook, F.A. , Hassan, D.M. , Alghazal, M.W. , ... Jalil, A.T. , Saleh Drug Research 73, 170–174 , 2023 2023 Citations: 7
Gingivectomy by Diode Laser and Conventional Method ( A Comparative Study) MWA Abdulkareem Hussain Alwan, Rasha Abduljaleel Althabit IOSR Journal of Dental and Medical Sciences 20 (7), 56-61 , 2021 2021 Citations: 4
Efficacy of Diode Laser 940 nm in Dentine Hypersensitivity reduction: a clinical trial MW Alghazali, FARM Al-Bazaz, MFJ Al-azzawi, SA Saadun Journal of Emergency Medicine, Trauma & Acute Care 2023 (3), 6 , 2023 2023 Citations: 3
Dental environment stress among Iraqi students: A qualitative study BF Alanbari, MJAL Juboori, MW Alghazali Journal of Emergency Medicine, Trauma & Acute Care 2023 (3), 3 , 2023 2023 Citations: 3
Covid-19 Vaccin Hesitancy among Iraqi Dentists AHA Madiha Fouad Jameel Al-azzawi, Maha Waleed Alghazali, Marwah M. Hareeja ... Journal of Medicinal and Chemical Sciences 6 (2), 424-432 , 2023 2023 Citations: 3
Evaluation of Gingegel Gel for the Treatment of Gingivitis: A randomized clinical trial AH Alwan, MW Alghazali, AA Hussain Journal of Emergency Medicine, Trauma & Acute Care 2023 (3), 9 , 2023 2023 Citations: 2
Evaluation of the Effect of Patient Related Factors on Periodontal Condition in a Sample of Iraqi Population: A Retrospective Study FAR Alwan, A.H., Alanbari, B.F., Alghazali, M.W., Hussain, A.A., Mahmood Al ... Journal of Medicinal and Chemical Sciences 6 (5), 1010–1031 , 2023 2023 Citations: 2
Contributions and therapeutic potential of tumor-derived microRNAs containing exosomes to cancer progression ATJ Hussein Riyadh Abdul Kareem Al-Hetty, Sada Jasim Abdulameer, Maha Waleed ... Gene Reports 29, 101672 , 2022 2022 Citations: 2
Comparative study of oral soft tissue operations using a laser vs. a scalpel AAH Maha Waleed Alghazali, Rasha Abduljaleel Althabit, Abdulkareem Hussain ... NeuroQuantology 20 (5), 488-491 , 2022 2022 Citations: 2
Solubility enhancement of meloxicam by binary and ternary solid dispersion MM Hareeja, IK Abbas, F Madiha, MW Alghazali Journal of Pharmaceutical Negative Results¦ Volume 13 (4), 116 , 2022 2022 Citations: 2
Comparative Histological Study of Dentinopulpal Responses in Class I Cavity Treated by Er: YAG Laser and Conventional Cavity Preparations: An in Vivo Trial MW Al-Gazali, AS Mahmood, LM Al-Azzawi, RK Jarjess Iraqi Journal of Laser 9 (B), 33-41 , 2010 2010 Citations: 2
A Systematic Review of case Reports of Neoplastic Changes in Epithelial lining of Dentigerous Cysts AH Murad, MS Merza, MW Alghazali Future Dental Research 3 (2), 49-56 , 2025 2025
Archive of SID. ir AH Alwan, BF Alanbari, MW Alghazali, AA Hussain, FARM Al_Bazaz 2023
Solubility Enhancement of Meloxicam by Binary and Ternary Solid Dispersion MW Hareeja, M.M. , Abbas, I.K. , Madiha, F. , Alghazali Journal of Pharmaceutical Negative Resultsthis link is disabled 13 (4), 116–124 , 2022 2022
Changes in oral health attitude and behavior of undergraduate Iraqi dental students AHA Madiha Fouad Jameel Al-azzawi, Maha Waleed Alghazali, Rasha Abduljaleel ... Bulletin of National Institute of Health Sciences 140 (1), 1407-1419 , 2022 2022
Abstracts from the 4 th Congress of the World Federation for Laser DentistryEuropean DivisionJuly 11–12, 2013Brussels, Belgium VGA Suter, HJ Altermatt, T Dietrich, PA Reichart, MM Bornstein, U Myron, ... Photomedicine and Laser Surgery 31 (12), 630-645 , 2013 2013
