Gaurav Bhargava

Scopus Publications

Recent Advances in Catalytic [5 + 3] Cycloadditions
Smile, Vipan Kumar, Rupesh Kumar, Dinesh Mahajan, Gaurav Bhargava
Advanced Synthesis and Catalysis, 2026
Higher‐order cycloadditions (HOCs) offer a robust and convergent strategy for the rapid assembly of complex molecular architectures. These transformations enable direct access to ring systems that are otherwise challenging to construct. Among them, the [5 + 3] cycloaddition has emerged as a versatile platform for the synthesis of eight‐membered carbo‐ and heterocycles, which are widely represented in bioactive natural products, pharmaceuticals, and functional materials. This review provides a comprehensive overview of developments in catalytic [5 + 3] cycloadditions from 2003 to the present, encompassing both transition metals and organocatalytic systems. Emphasis is placed on catalyst class, ligand design, activation mode, and substrate scope, as well as their influence on chemo‐, regio‐, and stereoselectivity, together with comparative performance data. Representative mechanistic proposals reported in the literature are discussed where relevant. Although most catalytic [5 + 3] processes proceed through stepwise pathways and are therefore best described as formal [5 + 3] cycloadditions, true pericyclic [5 π + 3 π ] cycloadditions are comparatively rare. Where applicable, this mechanistic distinction is clearly indicated in the corresponding sections.
Concentrated solar light-driven rapid and neat synthesis of quinazolines: a greener, sustainable, and an efficient approach
Gobind Kumar, Sarthak Sharma, Archna, Garima Sharma, Gaurav Bhargava, Jaspreet Kaur Rajput, Baljinder Singh, Rupesh Kumar
Research on Chemical Intermediates, 2026
Generation of a 3-Allyl/Propanylthiomethyl Ketene and their [4+2] Cycloadditions With 1,3-Diazabuta-1,3-dienes: Synthesis of 5-Allyl/propargyl-thio methyl Pyrimidinones
Rayees Ahmad Naikoo, Rupesh Kumar, Gaurav Bhargava
Chemistry and Biodiversity, 2026
The manuscript describes the explorations on [4+2] cycloaddition of newly in situ generated 3‐(allyl/propargyl‐thio)propanone as 2π‐components with functionalized 1,3‐diazabuta‐1,3‐dienes as 4π‐components for the synthesis of 5‐allyl/propargyl‐thio methyl pyrimidinones. The synthetic methodology is simple to operate, mild, and successful with a wide range of functionalized 1,3‐diazabuta‐1,3‐dienes in the development of functionalized pyrimidinones. The synthesis of these functionalized pyrimidinones is significant as functionalized pyrimidinones have diverse pharmacological relevance and are useful synthons for the synthesis of condensed heterocycles.
Recent Advances in [5 + 4] Cycloaddition Reactions: Catalysis, Mechanism, and Reaction Optimization
Gobind Kumar, Archna, Safiyah Ghumran, Neha Manhas, Parvesh Singh, Rupesh Kumar, Gaurav Bhargava
European Journal of Organic Chemistry, 2026
Medium‐sized rings, especially nine‐membered scaffolds, represent the core framework of several promising biologically active compounds. Among the various synthetic strategies reported, cycloaddition reactions, particularly [5 + 4] cycloaddition reactions, represent a unique and relatively underexplored class of pericyclic reactions that form the nine‐membered ring systems. However, the construction of a nine‐membered ring remains a significant challenge due to thermodynamic barriers, involving unfavorable enthalpic and entropic factors, as well as transannular interactions. Numerous catalytic systems have been developed to overcome these challenges. In this review article, we examined literature from 2000 to 2025 on [5 + 4] cycloaddition reaction, highlighting the role of various catalytic strategies such as metal catalysts, organocatalysts, and photocatalysts.
Visible-light mediated synthesis of bisthioglycolic acid derivatives via C-S bond formation complemented with DFT analysis
Gobind Kumar, Sarthak Sharma, Garima Sharma, Parvesh Singh, Gaurav Bhargava, Jaspreet Kaur Rajput, Rupesh Kumar
Phosphorus Sulfur and Silicon and the Related Elements, 2026
An innovative methodology has been developed to facilitate C-S bond formation, pioneering the synthesis of bisthioglycolic acid derivatives. This C-S bond formation is pivotal in synthesizing sulfur-containing bioactive scaffolds. Harnessing visible light as a plentiful, cost-effective, and eco-friendly catalyst and sustainable energy source holds immense potential for driving environmentally sensible innovations and advancing green technologies. The present protocols represent the first example of visible light-induced synthesis of bisthioglycolic acid derivatives. The methodology offered remarkable advantages such as solvent- and catalyst-free, cost-effectiveness, operational simplicity, environmentally benign reaction conditions, and excellent yields. Additionally, the DFT studies explored the global chemical reactivity properties of the synthesized compounds.
Design, Synthesis, and Anti-Inflammatory Activity of Functionalized 1,2,4,5-Tetrasubstituted-Pyrimidinone
Rayees Ahmad Naikoo, Diljeet Kumar, Nusrit Iqbal Andrabi, Yassir Arfath, Hemender Singh, Rupesh Kumar, Zabeer Ahmed, Gaurav Bhargava
Chemistry and Biodiversity, 2026
A highly efficient aza‐Michael addition reaction of 5‐amino pyrimidinones with α, β‐unsaturated olefins under optimized reaction conditions is reported. The resulting functionalized amino‐pyrimidinone‐based aza‐Michael mono‐adducts were obtained in good to excellent yields. These synthesized compounds were screened for their anti‐inflammatory potential in RAW264.7 macrophages. Among the synthesized compounds, we identified two derivatives, 3d and 3f , as potent anti‐inflammatory compounds. Our findings demonstrated that 3d and 3f maintained normal cell viability at the bioactive concentrations (1, 5, and 10 µM), effectively reduced the production of proinflammatory mediators such as nitric oxide and proinflammatory cytokines including interleukin‐6 and tumor necrosis factor‐α. In addition, immunoblotting results revealed that 3d and 3f downregulate the protein expression of i‐NOS and COX‐2 in LPS‐activated RAW264.7 macrophages. Furthermore, molecular docking was performed to elucidate the binding mechanism of these compounds and to establish a correlation between the in vitro results and the in silico data. Collectively, our results suggest that 3d and 3f attenuated the LPS‐induced inflammatory response in macrophages and can be a structural lead for the development of novel anti‐inflammatory agents.
Antidiabetic Evaluation of New Pyrimidine-Thiazoline Hybrids Endorsed With Enzyme Kinetic Studies and Computational Analysis
Gobind Kumar, Pule Seboletswe, Neha Manhas, Safiyah Ghumran, Nontobeko Gcabashe, Gaurav Bhargava, Almahi Idris, Md. Shahidul Islam, Parvesh Singh
Chemical Biology and Drug Design, 2025
The prevalence of diabetes mellitus (DM) poses a serious global health concern, given its substantial contribution to mortality rates. Millions of people worldwide are affected by this disease, which is associated with severe complications. Among the different strategies used to regulate diabetes, inhibition of carbohydrate‐hydrolyzing enzymes (α‐glucosidase and α‐amylase) has emerged as a promising therapeutic alternative. Accordingly, the present study explored the concept of molecular hybridization for synthesizing new pyrimidine‐thiazole molecular hybrids as potential α‐glucosidase and α‐amylase inhibitors and antioxidant agents. Among the tested hybrids, compound 8j emerged as the most potent inhibitor with 3‐fold (IC 50 = 36.23 ± 2.41 μM) more potency than standard drug acarbose (IC 50 = 103.25 ± 1.45 μM) against α‐glucosidase and 2‐fold (IC 50 = 38.42 ± 1.63 μM) greater potency than acarbose (IC 50 = 85.00 ± 0.85 μM) against α‐amylase. Compounds 8a (IC 50 = 37.84 μM) and 8j (IC 50 = 85.67 μM) displayed the strongest DPPH and NO scavenging activity, respectively, compared to ascorbic acid (IC 50 = 88.40 μM and 102.89 μM, respectively). In addition, kinetic studies revealed that compounds 4b , 8g , and 8j were noncompetitive inhibitors. Molecular docking studies were subsequently carried out to explore the protein‐ligand interactions of these compounds. The DFT studies further explored their reactivity characteristics while the ADME/T parameters revealed them to have more drug‐likeness properties than acarbose.
DES-Promoted Synthesis of 3,4-Dihydropyrimidinones and Their Antidiabetic and Antioxidant Evaluation Supported With Computational Studies
Gobind Kumar, Sahil Mishra, Pule Seboletswe, Nontobeko Gcabashe, Lalitha Gummidi, Neha Manhas, Talent Makhanya, Gaurav Bhargava, Almahi Idris, Md. Shahidul Islam, Parvesh Singh
Chemistry and Biodiversity, 2025
A series of 3,4‐dihydropyrimidinone (DHPM) derivatives was synthesized using a green deep eutectic solvent (DES) system composed of ZnCl2 and urea, which acted simultaneously as solvent, catalyst, and in situ substrate (urea). The synthesized compounds were evaluated for their antidiabetic potential via α‐glucosidase and α‐amylase inhibition assays, as well as for antioxidant activity using 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP), and nitric oxide (NO) scavenging assays. Among the series, compound 3f exhibited superior inhibitory activity against α‐glucosidase (IC50 = 35.25 µM) and α‐amylase (IC50 = 38.61 µM), being ∼2.3‐ and ∼2.6‐fold more potent, respectively, than the standard drug acarbose. In antioxidant evaluations, compound 3i (IC50 = 35.60 µM) demonstrated ∼2.9‐fold higher activity than gallic acid in the DPPH assay, whereas 3d (IC50 = 30.70 µM) and 3a (IC50 = 44.52 µM) showed ∼3.8‐ and ∼1.5‐fold higher activity in FRAP and NO scavenging assays, respectively. Molecular docking studies revealed key hydrogen bonding interactions of 3f with the active site residues of both enzymes, supported by favorable docking scores. Furthermore, density functional theory (DFT) studies revealed favorable electronic and reactivity profiles, whereas ADME/T predictions indicated good drug‐likeness. Overall, compound 3f shows strong potential as a lead antidiabetic agent for managing postprandial hyperglycemia.
Coconut waste–derived sulfonated magnetic biochar: an efficient catalyst for the synthesis of 2,3-dihydroquinazolinone
Sarthak Sharma, Gobind Kumar, Navneet Kaur, Gaurav Bhargava, Rupesh Kumar
Research on Chemical Intermediates, 2025
Recent Advances in Catalyst-Mediated [6 + 4] Cycloaddition Reactions: A Concise Review
Gobind Kumar, Archna Archna, Sahil Mishra, Safiyah Ghumran, Neha Manhas, Rupesh Kumar, Parvesh Singh, Gaurav Bhargava
European Journal of Organic Chemistry, 2025
Higher‐order cycloaddition reactions (CRs) are significant in providing quick access to different polycyclic and complex molecules. In particular, [6 + 4] CRs have been widely applied in the construction of 10‐membered rings, bridged molecules, and natural compounds. However, these reactions encounter several challenges, including achieving regio‐ and stereoselectivity, overcoming high activation energy barriers, and managing multiple reaction pathways. Over the past decade, numerous catalysts have been developed to address these challenges. The present review summarizes the reported research (2000–2024) on [6 + 4] CRs, highlighting various catalysts, including metal, Lewis acid, organocatalysts, and enzyme‐based catalysts.
High-temperature synergistic enhancement of structural, dielectric, and electrochemical properties in BiMnO3 and Ti-substituted Bi0.50Nd0.50Mn1-xTixO3 (x = 0.00, 0.05, and 0.10) ceramics
Aman Sen, Surinder Paul, Diksha, Malavika, Ritesh Kumar, Almas Munaf Mujawar, Vimal Sharma, Gaurav Bhargava
Ceramics International, 2025
Isoniazid-rhodanine molecular hybrids: design, synthesis, antimycobacterial activity and computational validation
Gobind Kumar, Sahil Mishra, Pule Seboletswe, Neha Manhas, Safiyah Ghumran, Françoise Roquet-Banères, Laurent Kremer, Gaurav Bhargava, Parvesh Singh
Rsc Advances, 2025
Recent Developments in [8 + 2] Types Cycloadditions
Gaurav Bhargava, Simranpreet K. Wahan, Pooja A. Chawla, Rupesh Kumar
Chemistryselect, 2025
Density Functional Study on Highly Energetic Nitro Compounds with Empirical Formula Cm(NO2)4 (m = 1–7)
Tnu Mahajan, Hitesh Sharma, Gaurav Bhargava
Chemistryselect, 2025
Theoretical Exploration on Polynitrobenzo/Heteroaryl Pyrazines as Useful High-Energy-Density Materials
Tnu Mahajan, Gaurav Bhargava, Hitesh Sharma
Chemistryselect, 2025
Isoniazid-Dihydropyrimidinone Molecular Hybrids: Design, Synthesis, Antitubercular Activity, and Cytotoxicity Investigations with Computational Validation
Gobind Kumar, Pule Seboletswe, Sahil Mishra, Neha Manhas, Safiyah Ghumran, Nagaraju Kerru, Françoise Roquet‐Banères, Maëlle Foubert, Laurent Kremer, Gaurav Bhargava, Parvesh Singh
Chemmedchem, 2025
Exploring the Multifunctional Properties of Ni1–xZnxFe2O4 (x = 0, 0.1, 0.2, and 0.3) Ferrites Synthesized by Sol–Gel Citrate Approach
A. Sen, S. Paul, S. Rialach, K. Shaheen, S. Prerna, Manokamna, P. Sharma, G. Bhargava
Physics of the Solid State, 2025
Organic Dye-Based Powder for the Visualization of the Latent Fingerprints and Cyanide Detection
Vishakha Thakur, Sanjeev Kumar, Sheikh Showkat Ahmad, Rashmi Sharma, Satwinderjeet Kaur, Gaurav Bhargava, Prabhpreet Singh
Chemistryselect, 2025
Theoretical Investigations on [3,3] Sigma tropic Rearrangements in 1-Formyl-2-Vinyl Cyclobutane/Lactam
Tnu Mahajan, Hitesh Sharma, Gaurav Bhargava
Chemistryselect, 2025
Rapid and Environmentally-Friendly Synthesis of Thiazolidinone Analogues in Deep Eutectic Solvent Complemented with Computational Studies
Gobind Kumar, Pule Seboletswe, Nontobeko Gcabashe, Sanjeev Dhawan, Neha Manhas, Gaurav Bhargava, Rupesh Kumar, Parvesh Singh
Chemistryopen, 2025
Recent developments in the mechanochemical mediated innovative approaches for cycloaddition reactions
Simranpreet K. Wahan, Pooja A. Chawla, Smile, Rajveer Kaur, Gaurav Bhargava
Synthetic Communications, 2025
A facile and one-pot synthesis of pyrimidinone thiazolidin-4-one bifunctional hybrids
Rayees Ahmad Naikoo, Aliya Tabassum, Rupesh Kumar, Nitin Tandon, Gaurav Bhargava
Journal of Sulfur Chemistry, 2025
Unlocking InhA: Novel approaches to inhibit Mycobacterium tuberculosis
Simranpreet K. Wahan, Gaurav Bhargava, Viney Chawla, Pooja A. Chawla
Bioorganic Chemistry, 2024
Butadienyl Ketene: An Unexplored Intermediate in Organic Synthesis
Maninderjeet K. Mann, Simranpreet K. Wahan, Gaurav Bhargava, Nitin Tandon
Synopen, 2024
Advancements in visible-light-induced oxidation of aromatic alcohols: Insights into photo-redox transformative pathways
Gobind Kumar, Gaurav Bhargava, Sanjay Kumar, Jaspreet Kaur Rajput, Baljinder Singh, Parvesh Singh, Rupesh Kumar
Inorganica Chimica Acta, 2024
Harnessing click chemistry for the discovery of fluorescent materials
Simranpreet K. Wahan, Gaurav Bhargava, Pooja A. Chawla
Dyes and Pigments, 2024
Density functional study on highly energetic organic azides with empirical formula Cn(N3)m
Tnu Mahajan, Gaurav Bhargava, Hitesh Sharma
International Journal of Quantum Chemistry, 2024
An eco-friendly, sustainable, and greener approach to the synthesis of Dihydroquinazolin-4(1H)-ones using a deep eutectic solvent
Gobind Kumar, Pule Seboletswe, Neha Manhas, Parvesh Singh, Gaurav Bhargava, Jaspreet Kaur Rajput, Rupesh Kumar
Journal of Heterocyclic Chemistry, 2024
A Computational Study on the Structural Prediction of InhA Inhibitors as Antimycobacterial Agents
Simranpreet K. Wahan, Shelly Pathania, Pooja A. Chawla, Gaurav Bhargava
Polycyclic Aromatic Compounds, 2024
Diastereo- and π-Facially Selective Hetero-Diels Alder Cycloaddition Reactions of 3-Butadienyl-2-Azetidinones with Diazo-Dienophiles
Maninderjeet Kaur Mann, Rashmi Sharma, Pooja Chawla, Rupesh Kumar, Gaurav Bhargava
Polycyclic Aromatic Compounds, 2024
A facile, regio and diastereoselective synthesis of functionalized azetidin-2-ones: Cu(I) mediated Kinugasa reaction of functionalized nitrones with acetylenic alcohols
Priyanka Sharma, Dinesh Mahajan, Vipan Kumar, Rupesh Kumar, Gaurav Bhargava
Synthetic Communications, 2024
Ultrasound assisted solvent-free approach for the synthesis of 4-thiazolidinone derivatives
Simranpreet K. Wahan, Pooja A. Chawla, Rupesh Kumar, Nitin Tandon, Gaurav Bhargava
Journal of Sulfur Chemistry, 2024
Synthesis of nitrogen-containing heterocyclic rings using grinding approach
Simranpreet K. Wahan, Gaurav Bhargava, Pooja A. Chawla
Solvent Free Synthesis Bioactive Heterocycles, 2023
A Facile, Mechanochemical, Solvent-, and Catalyst-Free Synthesis of Functionalized 4-Thiazolidinones
Simranpreet K Wahan, Pooja A Chawla, Parvesh Singh, Rupesh Kumar, Gaurav Bhargava
Synopen, 2023
Highly regioselective 6-exo-dig iodo/bromo cyclizations of functionalized 5-amino propargyl pyrimidinones: an efficient synthesis of functionalized pteridines
Rayees Ahmad Naikoo, Rupesh Kumar, Rashmi Sharma, Dinesh Mahajan, Gaurav Bhargava
Rsc Advances, 2023
Chlorophyll: A Greener Catalyst in Synthetic Transformations
Pooja A. Chawla, Simranpreet K. Wahan, Gaurav Bhargava
Synopen, 2023
Role of crown ethers as mediator in various chemical reactions
Simranpreet K. Wahan, Gaurav Bhargava, Pooja A. Chawla
Non Conventional Solvents, 2023
A new entrant in ketene family: Generation of 2-(3-Oxo-allyl)-isoindole-1,3-dione and their [4+2] Cycloadditions with 1,3-Diazabuta-1,3-dienes
Rayees Ahmad Naikoo, Rashmi Sharma, Rupesh Kumar, Gaurav Bhargava
Asian Journal of Organic Chemistry, 2023
Trio Role of Deep Eutectic Solvents in the Green Synthesis of 1,4-Dihydropyridine Synthesis via Hantzsch Reaction
Gobind Kumar, Gaurav Bhargava, Rupesh Kumar
Polycyclic Aromatic Compounds, 2023
Ultrasound-assisted Synthesis of Nitrogen and Oxygen Containing Heterocycles
Simranpreet K. Wahan, Gaurav Bhargava, Pooja A. Chawla
Current Organic Chemistry, 2023
Recent Developments in the Transformation of 3-amino-2-azetidinones
Priyanka Sharma, Rashmi Sharma, Vipan Kumar, Parvesh Singh, Gaurav Bhargava
Current Organic Chemistry, 2023
Deep eutectic solvents with ultrasonic energy as an environmentally benign and green approach for the synthesis of bisthioglycolic acid derivatives
Gobind Kumar, Parvesh Singh, Gaurav Bhargava, Baljinder Singh Gill, Jaspreet Kaur Rajput, Rupesh Kumar
Journal of Sulfur Chemistry, 2023
Serendipitous synthesis of 2,3-dihydroquinazolin-4(1H)-ones in ZnCl2/urea deep eutectic solvent
Gobind Kumar, Lungisani Khubone, Pule Seboletswe, Neha Manhas, Talent Makhanya, Gaurav Bhargava, Parvesh Singh
Arkivoc, 2023
Editorial: Protozoal infections: Treatment and challenges
Vipan Kumar, Gaurav Bhargava
Frontiers in Cellular and Infection Microbiology, 2022
Oxa-Michael Addition Reactions of 3-hydroxy-2-azetidinones: Synthesis of 1, 3, 4-Trisubstituted-2-Azetidinones
Priyanka Sharma, Maninderjeet Kaur Mann, Gaurav Bhargava
Letters in Organic Chemistry, 2022
Eosin Y photocatalyzed access to Biginelli reaction using primary alcohols via domino multicomponent cascade: an approach towards sustainable synthesis of 3,4-dihydropyrimidin-2(1H)-ones
GOBIND KUMAR, GAURAV BHARGAVA, YOGESH KUMAR, RUPESH KUMAR
Journal of Chemical Sciences, 2022
Recent Developments in the Synthesis of Bicyclic Condensed Pyrimidinones
Rayees Ahmad Naikoo, Rupesh Kumar, Vipan Kumar, Gaurav Bhargava
Current Organic Chemistry, 2022
Solvent-free mechanochemical synthesis of bisthioglycolic acid derivatives: an efficient and versatile strategy for carbon–sulfur bond formation
Rayees Ahmad Naikoo, Parvesh Singh, Rupesh Kumar, Gaurav Bhargava
Journal of Sulfur Chemistry, 2022
Influence of Ba2+ substitution on Structural, Dielectric, Thermal and Electrical behavior of La1-xBaxCo0.50Fe0.50O3 {0.10≤ x≤ 0.40} Cathode for SOFC
Research Journal of Chemistry and Environment, 2021
Structural, thermal and electrical properties of La0.80Sr0.20MnO3cathode of SOFCs
Manokamna, Surinder Paul, Arun Kumar, D. K. Sharma, K. L. Singh, G. Bhargava, A. P. Singh
Aip Conference Proceedings, 2021
Effect of sr2+doping on the structural, thermal, dielectric and electrical properties of la1-xsrxco0.50fe0.50 o3 {0.1≤ x≤ 0.4}cathode for sofcs
Manokamna, Surinder Paul, A. Singh, K. L. Singh, G. Bhargava, A. P. Singh
Rasayan Journal of Chemistry, 2021
7-Endo-trig Pictet–Spengler type cyclization of 5-alkylidene/arylidene-amino-3H-pyrimidin-4-ones: An efficient and diastereoselective synthesis of pyrimido[4,5-b] [1,4]benzodiazepines
Rayees Ahmad Naikoo, Rupesh Kumar, Parvesh Singh, Gaurav Bhargava
Synthetic Communications, 2021
Recent developments in the synthesis of tricyclic condensed pyrimidinones
Rayees Ahmad Naikoo, Rupesh Kumar, Vipan Kumar, Gaurav Bhargava
Synthetic Communications, 2021
3-Butadienyl-β-lactams: A useful synthon for functionalized heterocycles
Gaurav Bhargava, Maninderjeet K. Mann, Rayees Ahmad Naikoo
Synthetic Communications, 2020
Recent development in the synthesis of pyrrolin-4-ones/pyrrolin-3-ones
Priyanka Sharma, Rupesh Kumar, Gaurav Bhargava
Journal of Heterocyclic Chemistry, 2020
Rhodium-catalysed chemo- and regio-selective [3 + 2+2] cycloadditions of bis(methylenecyclopropanes) and alkynes: Synthesis of spirocyclic 5–7 condensed cycloheptenes
Bilash Kuila, Priyanka Sharma, Dinesh Mahajan, Prabhpreet Singh, Gaurav Bhargava
Synthetic Communications, 2020
A multifunctional perylenediimide-based dual-analyte chemodosimeter for specific and rapid detection of H2S and Pd0 in water, biofluids, live cells and solid state
Kapil Kumar, Sandeep Kaur, Satwinderjeet Kaur, Gaurav Bhargava, Subodh Kumar, Prabhpreet Singh
Journal of Photochemistry and Photobiology A Chemistry, 2020
Near-IR discriminative detection of H2S and Cysteine with 7-nitro-2,1,3-benzoxadiazole-perylenediimide conjugate in water, live cells and solid state: Mimicking IMP, INH and NOR/OR complimentary logic
Poonam Sharma, Kapil Kumar, Sandeep Kaur, Satwinderjeet Kaur, Gaurav Bhargava, Subodh Kumar, Prabhpreet Singh
Journal of Photochemistry and Photobiology A Chemistry, 2020
Nickel(0)-Catalyzed [3+2]-Cycloadditions of Bis(alkylidenecyclopropanes) with Diazenes: A Facile Synthesis of Functionalized Pyrazolidine-1,2-dicarboxylates
Bilash Kuila, Rayees Naikoo, Dinesh Mahajan, Prabhpreet Singh, Gaurav Bhargava
Synlett, 2019
Direct conversion of carboxylic acids to various nitrogen-containing compounds in the one-pot exploiting curtius rearrangement
Arun Kumar, Naveen Kumar, Ritika Sharma, Gaurav Bhargava, Dinesh Mahajan
Journal of Organic Chemistry, 2019
Coronene diimide-based self-assembled (fibre-to-disc) fluorescent aggregates for visualization of latent fingerprints
Kapil Kumar, Harminder Singh, Vanita Vanita, Ramesh Singh, Khashti Ballabh Joshi, Gaurav Bhargava, Subodh Kumar, Prabhpreet Singh
Sensors and Actuators B Chemical, 2019
Transition metal catalyzed [6 + 2] cycloadditions
Amit Anand, Prabhpreet Singh, Vipan Kumar, Gaurav Bhargava
Rsc Advances, 2019
Perylene diimide-Cu2+ based fluorescent nanoparticles for the detection of spermine in clinical and food samples: A step toward the development of a diagnostic kit as a POCT tool for spermine
Kapil Kumar, Sandeep Kaur, Satwinderjeet Kaur, Gaurav Bhargava, Subodh Kumar, Prabhpreet Singh
Journal of Materials Chemistry B, 2019
Self-Assembled nanofibers of perylene diimide for the detection of hypochlorite in water, bio-fluids and solid-state: Exogenous and endogenous bioimaging of hypochlorite in cells
Kapil Kumar, Sandeep Kaur, Satwinderjeet Kaur, Gaurav Bhargava, Subodh Kumar, Prabhpreet Singh
Journal of Materials Chemistry B, 2019
Microstructural (self-assembly) and optical based discrimination of Hg2+, CN− and Hg(CN)2 ion-pair; Hg2+ promoted-ESIPT assisted guanylation of thiourea
Harminder Singh, Gaurav Bhargava, Subodh Kumar, Prabhpreet Singh
Sensors and Actuators B Chemical, 2018
[2+2] Cycloadditions of Sorbyl Tosylate with Imines/1-Azadienes: A One-Pot Domino Approach for α-Alkylidene-β-lactams and Their Computational Studies and Antimicrobial Evaluation
Yogesh Kumar, Preet Mohinder Singh Bedi, Prabhpreet Singh, Adebayo A. Adeniyi, Ashona Singh-Pillay, Parvesh Singh, Gaurav Bhargava
Chemistryselect, 2018
ESIPT-Based Dual Chemosensor for Sequential Detection of Cd2+/Zn2+ and Nucleoside Triphosphates in Water: Application in Logic Gates
Harminder Singh, Rashmi Sharma, Gaurav Bhargava, Subodh Kumar, Prabhpreet Singh
Chemistryselect, 2018
Dissymmetric Bay -Functionalized Perylenediimides
Prabhpreet Singh, Kapil Kumar, Gaurav Bhargava, Subodh Kumar
Synlett, 2018
Quadruple-signaling (PET, ICT, ESIPT, –C[dbnd]N– rotation) mechanism-based dual chemosensor for detection of Cu2+ and Zn2+ ions: TRANSFER, INH and complimentary OR/NOR logic circuits
Harminder Singh, Gaurav Bhargava, Subodh Kumar, Prabhpreet Singh
Journal of Photochemistry and Photobiology A Chemistry, 2018
Acetylenic Ester Promoted Tandem Ring Opening of Dienyl Thiazolidin-4-ones and Cyclizations: A Facile and Chemoselective Synthesis of Functionalized Pyridine-2-carboxylates
Gaurav Bhargava, Bilash Kuila, Kapil Kumar, Dinesh Mahajan, Prabhpreet Singh
Synlett, 2018
Transition-Metal-Catalyzed [3+2+2] Cycloaddition Reactions
Bilash Kuila, Maninderjeet Kaur, Prabhpreet Singh, Gaurav Bhargava
European Journal of Organic Chemistry, 2018
Fluorometric differential detection of Zn2+ and Cu2+ by picolylamine appended pyrimidinone-based receptor: Application in mimicking TRANSFER and INH logic gate
Prabhpreet Singh, Harminder Singh, Rashmi Sharma, Sanjeev Dhawan, Parvesh Singh, Gaurav Bhargava, Subodh Kumar
Journal of Photochemistry and Photobiology A Chemistry, 2018
Self-assembled small molecule based fluorescent detection of serum albumin proteins: Clinical detection and cell imaging
Prabhpreet Singh, Lalit Singh Mittal, Sandeep Kaur, Satwinderjit Kaur, Gaurav Bhargava, Subodh Kumar
Sensors and Actuators B Chemical, 2018
Controllable supramolecular self-assemblies (rods-wires-spheres) and ICT/PET based perylene probes for palladium detection in solution and the solid state
Kapil Kumar, Gaurav Bhargava, Subodh Kumar, Prabhpreet Singh
New Journal of Chemistry, 2018
AIE + ESIPT based red fluorescent aggregates for visualization of latent fingerprints
Harminder Singh, Rashmi Sharma, Gaurav Bhargava, Subodh Kumar, Prabhpreet Singh
New Journal of Chemistry, 2018
Multifunctional metallo-supramolecular interlocked hexagonal microstructures for the detection of lead and thiols in water
Prabhpreet Singh, Lalit Singh Mittal, Kapil Kumar, Poonam Sharma, Gaurav Bhargava, Subodh Kumar
Chemical Communications, 2018
Copper(I)-Catalyzed Regioselective C-H Amination of N-Pyridyl Imines Using Azidotrimethylsilane and TBHP: A One-Pot, Domino Approach to Substituted Imidazo[4, 5-b]pyridines
Nisha, Gaurav Bhargava, Yogesh Kumar
Chemistryselect, 2017
Ionic Self-Assembled Platform of Perylenediimide–Sodium Dodecylsulfate for Detection of Spermine in Clinical Samples
Prabhpreet Singh, Lalit Singh Mittal, Gaurav Bhargava, Subodh Kumar
Chemistry an Asian Journal, 2017
‘To kill many birds with one stone’: Addressing half-adder, half-subtractor, demultiplexer, 2-to-4 decoder, comparator, keypad lock with unimolecular system
Prabhpreet Singh, Harminder Singh, Gaurav Bhargava, Subodh Kumar
Sensors and Actuators B Chemical, 2017
Perylene diimide-based organic π-motif for differentiating CN- and F- ions by electron-transfer and desilylation mechanisms: Applications to complex logic circuits
Prabhpreet Singh, Lalit Singh Mittal, Harminder Singh, Gaurav Bhargava, Subodh Kumar
New Journal of Chemistry, 2017
Nanomolar Cu2+Detection in Water Based on Disassembly of AIEgen: Applications in Blood Serum, Cell Imaging and Complex Logic Circuits
Prabhpreet Singh, Harminder Singh, Vanita Vanita, Rashmi Sharma, Gaurav Bhargava, Subodh Kumar
Chemistryselect, 2016
Highly chemo-and diastereo-selective synthesis of 2,6-diazabicyclo[3.2.0]heptan-7-ones, pyrrolidines and perhydroazirino[2,3-c]pyrroles
Arkivoc, 2016
[2 + 2] Cycloaddition Reactions of Butadienyl Ketene with 1,4-Diazabuta-1,3-dienes: Synthesis of Functionalized Butadienyl-4-iminomethyl-azetidin-2-ones and Butenylidene-butadienyl-[2,2′-biazetidine]-4,4′-diones
Deepak Bains, Yogesh Kumar, Prabhpreet Singh, Gaurav Bhargava
Journal of Heterocyclic Chemistry, 2016
Tandem Aza-Michael and Intramolecular Amidic Ring-Opening Reactions of β-Lactams: A Facile Synthesis of 4-Oxo-4,5-dihydro-1 H -pyrroles from β-Lactam Synthons
Gaurav Bhargava, Priyanka Sharma, Maninder Mann, Bilash Kuila, Prabhpreet Singh
Synlett, 2016
Recent developments in the synthesis of condensed β-lactams
Yogesh Kumar, Prabhpreet Singh, Gaurav Bhargava
Rsc Advances, 2016
Cu(i) mediated Kinugasa reactions of α,β-unsaturated nitrones: A facile, diastereoselective route to 3-(hydroxy/bromo)methyl-1-aryl-4-(-styryl)azetidin-2-ones
Yogesh Kumar, Prabhpreet Singh, Gaurav Bhargava
New Journal of Chemistry, 2016
Self-assembled nanorods of bay functionalized perylenediimide: Cu2+ based 'turn-on' response for INH, complementary NOR/OR and TRANSFER logic functions and fluorosolvatochromism
Prabhpreet Singh, Kapil Kumar, Gaurav Bhargava, Subodh Kumar
Journal of Materials Chemistry C, 2016
Highly chemo- and diastereo-selective synthesis of 2,6-diazabicyclo[3.2.0]heptan-7-ones, pyrrolidines and perhydroazirino[2,3-c]pyrroles
Yogesh Kumar, Bilash Kulia, Prabhpreet Singh, Gaurav Bhargava
Arkivoc, 2016
A facile and highly chemoselective synthesis of 1-thia-3: A,6-diaza-benzo [e] azulen-3-ones by 7- exo-dig / trig halocyclizations
Bilash Kuila, Dinesh Mahajan, Prabhpreet Singh, Gaurav Bhargava
Rsc Advances, 2016
Diphenylpyrimidinone-salicylideneamine-new ESIPT based AIEgens with applications in latent fingerprinting
Prabhpreet Singh, Harminder Singh, Rashmi Sharma, Gaurav Bhargava, Subodh Kumar
Journal of Materials Chemistry C, 2016
A facile and chemoselective synthesis of 1,4-benzodiazepin-2-ones and dienyl thiazolidin-4-ones
Bilash Kuila, Yogesh Kumar, Dinesh Mahajan, Kapil Kumar, Prabhpreet Singh, Gaurav Bhargava
Rsc Advances, 2016
Self-assembled vesicle and rod-like aggregates of functionalized perylene diimide: Reaction-based near-IR intracellular fluorescent probe for selective detection of palladium
Prabhpreet Singh, Lalit Singh Mittal, Vanita Vanita, Kapil Kumar, Amandeep Walia, Gaurav Bhargava, Subodh Kumar
Journal of Materials Chemistry B, 2016
Triple-signaling mechanisms-based three-in-one multi-channel chemosensor for discriminating Cu2+, acetate and ion pair mimicking AND, NOR, INH and IMP logic functions
Prabhpreet Singh, Harminder Singh, Gaurav Bhargava, Subodh Kumar
Journal of Materials Chemistry C, 2015
Nickel catalyzed [3+2] cycloaddition reaction of bis(methylenecyclopropane) with cyclic and acyclic dienophiles
Bilash Kuila, Dinesh Mahajan, Prabhpreet Singh, Gaurav Bhargava
Tetrahedron Letters, 2015
Diastereo- and facially selective imino-diels-alder cycloaddition of 2-azeditinone-tethered 1-azadiene: Synthesis of functionalized (2-oxo-4-styrylazetidin-3-yl)-pyridine hybrids
Gaurav Bhargava, Yogesh Kumar, Prabhpreet Singh
Synlett, 2015
Bay functionalized perylenediimide as a deaggregation based intracellular fluorescent probe for perchlorate
Prabhpreet Singh, Lalit Singh Mittal, Vanita Vanita, Rahul Kumar, Gaurav Bhargava, Amandeep Walia, Subodh Kumar
Chemical Communications, 2014
Rhodium-catalyzed intramolecular [3+2+2] cycloadditions between alkylidenecyclopropanes, alkynes, and alkenes
Marisel Araya, Moisés Gulías, Israel Fernández, Gaurav Bhargava, Luis Castedo, José Luis Mascareñas, Fernando López
Chemistry A European Journal, 2014
Metal-free diastereoselective synthesis of diaza-bicyclo[3.2.0]heptan-7-one and its transformation to functionalized proline esters
Yogesh Kumar, Bilash Kuila, Dinesh Mahajan, Prabhpreet Singh, Balaram Mohapatra, Gaurav Bhargava
Tetrahedron Letters, 2014
N-Propargylated isatin-Mannich mono- and bis-adducts: Synthesis and preliminary analysis of in vitro activity against Tritrichomonas foetus
Nisha, Kewal Kumar, Gaurav Bhargava, Kirkwood M. Land, Kai-Hsiang Chang, Reena Arora, Somdutta Sen, Vipan Kumar
European Journal of Medicinal Chemistry, 2014
Perylene diimide appended with 8-hydroxyquinoline for ratiometric detection of Cu2+ ions and metal displacement driven "turn on" cyanide sensing
Prabhpreet Singh, Lalit Singh Mittal, Sandeep Kumar, Gaurav Bhargava, Subodh Kumar
Journal of Fluorescence, 2014
β-Lactam synthon-interceded diastereoselective synthesis of functionalized octahydroindole-based molecular scaffolds and their in vitro cytotoxic evaluation
Pardeep Singh, Raghu Raj, Gaurav Bhargava, Denver T. Hendricks, Sachin Handa, LeGrande M. Slaughter, Vipan Kumar
European Journal of Medicinal Chemistry, 2012
Regio- and diastereoselective nitroso Diels-Alder cycloaddition reactions of 3-dienyl-2-azetidinones with nitrosoarenes
Amit Anand, Gaurav Bhargava, Pardeep Singh, Saloni Mehra, Vipan Kumar, Mohinder P. Mahajan, Parvesh Singh, Krishna Bisetty
Letters in Organic Chemistry, 2012
β-lactam-synthon-interceded, facile, one-pot, diastereoselective synthesis of functionalized tetra/Octahydroisoquinolone derivatives
Raghu Raj, Vishu Mehra, Pardeep Singh, Vipan Kumar, Gaurav Bhargava, Mohinder P. Mahajan, Sachin Handa, LeGrande M. Slaughter
European Journal of Organic Chemistry, 2011
Nickel-catalyzed [3+2+2] cycloadditions between alkynylidenecyclopropanes and activated alkenes
Lucía Saya, Gaurav Bhargava, Miguel A. Navarro, Moises Gulías, Fernando López, Israel Fernández, Luis Castedo, José L. Mascareñas
Angewandte Chemie International Edition, 2010
Diastereoselective approach to novel octahydroisoquinolones and an extension to its one-pot synthesis
Pardeep Singh, Gaurav Bhargava, Vipan Kumar, Mohinder P. Mahajan
Tetrahedron Letters, 2010
Antibacterial activity of some novel tetrasubstituted pyrimidinones derivatives
International Journal of Pharmacy and Pharmaceutical Sciences, 2010
A regio and diastereoselective transformation of 3-dienyl-2-azetidinones to novel pyrroloxazine
Amit Anand, Gaurav Bhargava, Vipan Kumar, Mohinder P. Mahajan
Tetrahedron Letters, 2010
Chemo- and regioselective imino Diels-Alder reactions: synthesis of functionalized novel quinolin-3-one and quinoline derivatives
Mohinder P. Mahajan, Chander Mohan, Gaurav Bhargava
Heterocycles, 2010
Palladium-catalyzed [3C + 2C + 2C] cycloaddition of enynylidenecyclopropanes: Efficient construction of fused 5-7-5 tricyclic systems
Gaurav Bhargava, Beatriz Trillo, Marisel Araya, Fernando López, Luis Castedo, José L. Mascareñas
Chemical Communications, 2010
1,3,4-Trisubstituted-2-azetidinone derivatives as novel receptors for bismuth(III) ion-selective electrodes: Application in pharmaceutical and glass samples
Rakesh Kumar Mahajan, Rajiv Kumar Puri, Gaurav Bhargava, Mohinder Pal Mahajan
Analytical Letters, 2009
Regioselective nitroso diels-alder cycloaddition reactions of 50-dienyl pyrimidinones and transformation to novel 4-amino-alcohol tethered pyrimidinones
Mohinder P. Mahajan, Amit Ȧnand, Gaurav Bhargava, Pardeep Singh
Heterocycles, 2009
Bicyclic 6-6 systems with one bridgehead (ring junction) nitrogen atom: Three extra heteroatoms 2:1
Comprehensive Heterocyclic Chemistry III, 2008
PASS-assisted exploration of antidepressant activity of 1,3,4-trisubstituted-β-lactam derivatives
Munish Mittal, Rajesh K Goel, Gaurav Bhargava, Mohinder P Mahajan
Bioorganic and Medicinal Chemistry Letters, 2008
Regio- and π-facial selective Lewis acid interceded Diels-Alder reactions of α-dienyl-β-lactams: an indepth analysis
Gaurav Bhargava, Amit Anand, Mohinder P. Mahajan, Takao Saito, Ken Sakai, Chitrani Medhi
Tetrahedron, 2008
Regio- and chemoselective unprecedented imino-Diels-Alder reactions of 1-substituted unactivated dienes with N-aryl imines - Part II
Mohinder Mahajan, Gaurav Bhargava, Takao Saito
Synlett, 2008
Lewis acid promoted imino Diels-Alder reactions of 5-dienyl pyrimidinones with N-aryl/naphthyl imines: synthesis of novel quinoline/benzoquinoline derivatives
Gaurav Bhargava, Chander Mohan, Mohinder P. Mahajan
Tetrahedron, 2008
A Facile Sodium Alkoxide Mediated Ring Opening of Unactivated α-dienyl-βlactams: Synthesis of Unnatural Multicomponent β-aminodienoic Esters
Mohinder P. Mahajan, Amit Anand, Gaurav Bhargava, Maninder Singh Hundal
Heterocycles, 2007
Lewis acid promoted aza Diels-Alder reactions of acyclic unactivated 5-dienyl pyrimidinones with N-arylimines: synthesis of novel quinoline derivatives
Gaurav Bhargava, Vipan Kumar, Mohinder P. Mahajan
Tetrahedron Letters, 2007
An unprecedented methylene oxidation accompanying the aza Diels-Alder reactions of acyclic unactivated alkenes: synthesis of novel quinolin-3-one substituted pyrimidinone derivatives
Chander Mohan, Gaurav Bhargava, A.P.S. Pannu, Mohinder P. Mahajan
Tetrahedron Letters, 2007
Tandem [2+2] cycloaddition and Cope rearrangement in reactions of cross-conjugated azatrienes with conjugated ketenes: a facile single step synthesis of novel azocinone derivatives
Parvesh Singh, Gaurav Bhargava, Mohinder P. Mahajan
Tetrahedron, 2006
A convenient route to biologically important quinazolines using N-arylamino-1,3-diazabuta-1,3-dienes
M. P. Mahajan, Vipan Kumar, Gaurav Bhargava, Promita D. Dey
Synthesis, 2005
Highly diasteroselective and remarkably π-facially selective lewis acid-catalysed diels-alder cycloaddition reactions: Access to novel 1,3,4-trisubstituted 2-azetidinones
Gaurav Bhargava, Mohinder P. Mahajan, Takao Saito, Takashi Otani, Mai Kurashima, Ken Sakai
European Journal of Organic Chemistry, 2005
Thiosemicarbazonates of silver(I): Synthesis, spectroscopy and reactivity towards triphenylphosphine
Indian Journal of Chemistry Section A Inorganic Physical Theoretical and Analytical Chemistry, 2003

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