Vegetable Oils of Plants from the Ecuadorian Amazon for the Design of a Cosmetic Cream MONICA PAULINA ECHEVERRIA GUEVARA, Luis Ramón Bravo Sánchez, Jannys Lizeth Rivera Barreto, Verónica Cecibel Granda Escobar, Brayan Jasmany Agila Guanoluisa Revista Politecnica, 2025 En la actualidad, la implementación de aceites vegetales en distintas industrias ha crecido de manera exponencial y tiene gran repercusión sobre el área cosmética. El diseño de una crema podría brindar mejoría en la piel y atraer nuevos mercados. La piel con el tiempo pierde nutrientes, oligoelementos, colágeno y ácido hialurónico ocasionando problemas de deshidratación. Los aceites de las tres plantas nativas amazónicas Oenocarpus bataua Mart, Mauritia flexuosa L.f. y Fevillea cordifolia L. poseen principios activos con propiedades antioxidantes que pueden beneficiar la piel en aspectos de rejuvenecimiento, luminosidad y extensibilidad. El objetivo de este estudio fue desarrollar una crema cosmética hidratante y nutritiva a base de aceites vegetales esenciales y fijos de Oenocarpus bataua, Mauritia flexuosa y Fevillea cordifolia, mediante un proceso de optimización de formulación que garantice la ausencia de compuestos sintéticos y cumpla con los estándares de calidad cosmética. Se elaboraron 14 formulaciones con el uso del software Design Expert. Se diseñó la crema mediante un diseño de mezclas Simplex Lattice Desing. Se aplicó la escala hedónica para los análisis sensoriales. El modelo matemático cuadrático de mezcla fue óptimo con una diferencia menor de 0.2 entre el R2-ajustado y el predicho teniendo una adecuada precisión. La mejor formulación fue la número 7 (15 g manteca de cacao, 7.5 g aceite de M. flexuosa y 7.5 g O. bataua, 0.3 g aceite esencial, 65.3 g agua, 3.4 g de montanov 202 y 1 g de montanov 68) con un pH de 6.53 y como variables de respuestas la viscosidad de 4275 mPa.s, y la extensibilidad de 7 cm2, la cual tuvo mayor aceptación por los participantes. Esta crema cosmética puede generar un nuevo mercado en productos agroindustriales que beneficien a las comunidades productoras de la Región Amazónica Ecuatoriana.
Conceptual Design of the Process for Making Cosmetic Emulsion Using Amazonian Oils Estela Guardado Yordi, Irma Sofia Guambuguete Guaman, Mayra Elizabeth Freire Fuentes, Matteo Radice, Laura Scalvenzi, Reinier Abreu-Naranjo, Luis Ramón Bravo Sánchez, Amaury Pérez Martínez Processes, 2025 In recent years, there has been a growing interest in natural and sustainable cosmetic ingredients, particularly those derived from Amazonian plant oils. The present research focuses on the creation of a prototype cosmetic emulsion from two Amazonian oils, morete oil (Mauritia flexuosa L.f.) and ungurahua oil (Oenocarpus bataua Mart). The aim of the study was to develop a conceptual design of the process for making cosmetic emulsion using Amazonian oils. The methodology consisted of observational data collection, definition of unit operations and equipment, and process simulation. The design was simulated using SuperPro Designer V10.0. Experimental data, unit operations, equipment, and operation time confirmed the feasibility of a conceptual process design for scaling up. In the conceptual design, an operation time of 4.25 h was estimated, which would allow the production of two or more batches per day, depending on the demand, and the initial investment was expected to be recovered within 6.24 years. This study highlights the potential application of Amazonian oils in the cosmetic industry, promoting financially viable, natural, and ecologic products. Future research should analyze extraction yields, alternative strategies for efficient scale-up, and the long-term stability of emulsions under different storage conditions.
The Design of an Intensified Process and Production Plant for Cosmetic Emulsions Using Amazonian Oils Laura Scalvenzi, Estela Guardado Yordi, Edgar Wilfrido Santamaría Caño, Ibeth Nina Avilez Tolagasi, Matteo Radice, Reinier Abreu-Naranjo, Lianne León Guardado, Luis Ramón Bravo Sánchez, Amaury Pérez Martínez Processes, 2025 The cosmetic industry in the Ecuadorian Amazon region faces the challenge of competitively integrating locally sourced plant-based raw materials into efficient and sustainable production processes. This study proposes the design of a pilot plant for the production of a cosmetic emulsion (CE), using oils extracted from Morete (Mauritia flexuosa) and Ungurahua (Oenocarpus bataua), with a focus on process intensification to reduce both capital investment and resource consumption. Process design methodologies and computational simulation (SuperPro Designer V10) were applied, along with Systematic Layout Planning (SLP) principles to optimize spatial configuration. The intensified scheme enabled the integration of extraction lines, reducing the number of major equipment units from 12 to 9 and lowering the investment from USD 1,016,000 to USD 719,000. Energy and environmental indicators showed consumption levels of 5.86 kWh and 48.4 kg of water per kg of cream, which are lower than those reported for other natural cosmetics plants. The intensified design achieved a Net Present Value (NPV) of USD 577,000 and a payback period of 3.93 years. Furthermore, solid by-products were valorized through circular economy principles. This approach offers a feasible, viable, and sustainable solution for the utilization of these Amazonian oils in the cosmetic industry.
Optimization of total extractible from Maytenus macrocarpa bark assisted by ultrasound by using the response surface methodology Afinidad, 2020
Evaluation of the synergistic effects of antioxidant activity on mixtures of the essential oil from Apium graveolens L., Thymus vulgaris L. and Coriandrum sativum L. using simplex-lattice design Yasiel Arteaga Crespo, Luis Ramón Bravo Sánchez, Yudel García Quintana, Andrea Silvana Tapuy Cabrera, Abdel Bermúdez del Sol, Dorys Magaly Guzmán Mayancha Heliyon, 2019 Essential oils (EOs) are known for their antioxidant properties, and are widely employed in the food industry as preservatives. They can be used as condiments or as preservatives to achieve certain organoleptic effects for consumers. The aim of this research was to evaluate antioxidant activity in mixtures of three EOs: Apium graveolens L., Thymus vulgaris L. and Coriandrum sativum L., using the Simplex Lattice Mixture Design. Ultimately, a linear model was used, as it best adjusted to the experimental behavior, and it allowed the prediction of EOs mixtures antioxidant activity, determined by FRAP and ABTS techniques. The mixture of the three EOs that showed the best antioxidant activity and also had the highest synergistic effect, was composed of 66.7% of T. vulgaris, 16.7% of C. sativum and 16.7% of A. graveolens. The greatest contribution to the potentiation of antioxidant activity was shown by T. vulgaris followed by A. graveolens and then C. sativum.
Traditional use of medicinal plants by the population of the municipality of Santa Clara, Cuba Journal of Pharmacy and Pharmacognosy Research, 2018
Physical-chemical and phytotoxic evaluation of treated/reclaimed wastewater intended for agricultural irrigation Revista De Toxicologia, 2015
Chemical and pharmacological evaluation of medicinal plants for use as herbal active pharmaceutical ingredients in local production laboratories Anales De La Academia De Ciencias De Cuba, 2015
