2017-2020 BSC CHEMISTRY - GOVT. ARTS COLLEGE, COIMBATORE.
2020-2022 MSC CHEMISTRY - VELLORE INSTITUTE OF TECHNOLOGY, VELLORE
2022 - CURRENT - PH.D. - VELLORE INSTITUTE OF TECHNOLOGY, VELLORE
RESEARCH, TEACHING, or OTHER INTERESTS
Chemistry, Electrochemistry, Materials Chemistry, Waste Management and Disposal
Enhanced Electrochemical Nitrofurantoin Detection Using Bimetallic (Al, Mn) MOFs-Coated Glassy Carbon Electrode Chettipalayam Arunasalam Dhayanithi, Saravanan Srinidhi, Santhakumar Subhashini Devi, Natarajan Raman, Sundaram Ganesh Babu Applied Organometallic Chemistry, 2025 Preserving our environment is essential for sustaining life, yet contaminants like nitrofurantoin—a widely used antibacterial drug—pose significant risks to both ecological and human health. In the quest for a pollution‐free environment, the detection of such contaminants is critical. This study focuses on the development of monometallic and bimetallic MOFs, renowned for their properties, like high surface area and tunable characteristics, which make them ideal for electrochemical sensing applications. The preparation involves the hydrothermal synthesis of monometallic and bimetallic organic frameworks with aluminium (Al) and manganese (Mn) metals using 3,5‐pyridine dicarboxylic acid (PDC), with successful formation confirmed by XRD, FT‐IR, SEM, and XPS. The electrochemical sensing properties of these MOFs are studied by using CV and DPV. Various optimization studies are carried out to detect the optimal MOF, and it is found that AlMn‐PDC MOF/GCE shows high electrochemical performance, with the synergistic effect between Al and Mn enhancing the overall activity. Furthermore, real sample analysis confirmed the effectiveness of the sensor by achieving recoveries of 98.3% and 99.5% in milk and tap water, respectively. These findings highlight the potential of the AlMn‐PDC MOF/GCE as a highly sensitive and selective tool for nitrofurantoin detection, emphasizing the role of bimetallic MOFs in environmental monitoring applications.
Comparative evaluation of antimicrobial activity of spinel structured transition metal ferrites supported on reduced graphene oxide against pathogenic strains of bacteria and fungi Rajendran Lakshmi Priya, Chettipalayam Arunasalam Dhayanithi, Boopathi Shagunthala Hariprasad, Radhakrishnan Vidya, Sundaram Ganesh Babu Nanotechnology, 2024 One of the global challenges for living things is to provide pollution and harmful microbes-free environment. In this study, magnetically retrievable spinel-structured manganese zinc ferrite (Mn0.5Zn0.5Fe2O4) (MZF) was synthesized by a facile solvothermal method. Further, the MZF with different weight percentages (10 wt%, 50 wt%, and 80 wt%) were supported on reduced graphene oxide (rGO). The phase purity and morphology of MZF and MZF/rGO nanocomposite were confirmed by x-ray diffraction technique and scanning electron microscopy, respectively. The Fourier transform infrared spectroscopy, Raman, UV–visible spectroscopy, and thermogravimetric analyses of the as-synthesized nanocomposites were examined for the detection of various chemical groups, band gap, and thermal properties, respectively. The MZF/rGO nanocomposite exhibited significant antibacterial and antifungal activity against Eggerthella lenta, Enterococcus faecalis, Klebsiella pneumonia, Pseudomonas aeruginosa, and Candida albicans compared to bare MZF and rGO. The high surface area of rGO plays a crucible role in antimicrobial analysis. Additionally, the antibacterial and antifungal activity is compared by synthesizing various metal ferrites such as MnFe2O4, ZnFe2O4, and Fe3O4. The 50 wt% MZF/rGO nanocomposite exhibits significantly high antibacterial activity. However, 10 wt% MZF/rGO nanocomposite shows good antifungal activity than Fe3O4, MnFe2O4, ZnFe2O4, MnZnFe2O4, 50 wt%, and 80 wt% MZF/rGO nanocomposites. These findings suggest that the prepared ferrite nanocomposites hold promise for microbial inhibition.
