Lymphocyte subpopulations among pregnant women in Agbor, Delta State, Nigeria Ophori Endurance Anthony, Isibor Ndudi Clement Asian Pacific Journal of Tropical Disease, 2012 To determine the peripheral blood CD3 and CD8 T-lymphocytes subpopulation in healthy pregnant women in our environment. Pregnant women attending the antenatal care clinic (ANC) of the Central Hospital, Agbor, Nigeria, who gave informed consent were recruited for the study. Blood samples (10 mL) was collected by venipuncture from 121 healthy pregnant women (aged 17-47 years; mean 28.5±0.43). Tweenty four non-pregnant healthy women (aged 18-30years; mean 21.12±0.64) were enrolled as control. CD3+ and CD8+ counts were determined with the Partec flow cytometer. The mean CD3+ count for pregnant women was 1311.10±71.50 μ/L when compared to the controls which was 9.67±0.99 μ/L. This was statistically significant(P<0.005). The mean CD8+ count for pregnant women was 340.91±18.53 μ/L as against the 583.58± 47.30 μ/L (P>0.005). Primigravidas had a higher CD3+ mean count than multiparas while mean CD8+ count was higher in multiparas than in primigravidas. Similarly, the mean CD3+ count was significantly different between all the trimesters with the highest count of 1, 353.23±43.90 μ/L in the first trimester as compared to the 9.67±0.99 μ/L in the control. Mean CD3+ was highly significant in pregnant women with history of previous abortions while the CD8+ cells were not. The results suggest the need for routine determination of T lymphocyte subsets apart from CD4 in pregnant women attending ANC clinic to prevent any possible immunological /pregnancy disorder during the period of pregnancy.
Immunological response to Helicobacter pylori among healthy volunteers in Agbor, Nigeria E. Ophori, C. Isibor, S. Onemu, E. Johnny Asian Pacific Journal of Tropical Disease, 2011 Abstract Objective To determine Helicobacter pylori ( H. pylori) immunologically. Method The seroprevalence of H. pylori infection was determined by ELISA technique in 380 individuals who gave informed consent, comprising 180 males (47.4%) and 200 females (52.6%) in Agbor, Nigeria. 124 (27.4%) of the subjects lived in the rural communities while 276 (72.6%) lived in the urban areas of Agbor. They were aged 1 to over 70 yr [(mean age±SD)=(39±9. 42) yr]. Five milliliter of clotted blood was obtained from each subject for specific HP-IgG antibodies. Results Antibodies to H. pylori were detected in serum of 159 males (88.3%) and 182 females (91.0%). This was not statistically significant ( P > 0.05). A total of 341 (89.7±21.4%) subjects presented anti- H. pylori antibodies. The prevalence of H. pylori increased with age from 14.8% in age group 1–9 yr to 100% in age group 30-39 yr and 60–69 yr. At above 70 yr, the seroprevalence decreased to 93.3%. Conclusions The prevalence of H. pylori in Agbor is very high among adults while comparatively low among children. Since a lot of factors have been attributed to affect the rate of infection, increased standard of living and improved public health measures are encouraged and studies on the development and administration of an effective vaccine is recommended.
RECENT SCHOLAR PUBLICATIONS
Assessment of Bacterial Contamination of Mobile Phones Used by Students in University of Delta, Agbor, Nigeria C Isibor, AJ Grandy, E Efordili, IA Patience West African Journal of Allied Health Sciences 2 (1) , 2026 2026
Public Health Implications of Bacterial Contamination of Mobile Phones Among Students at the University of Delta, Agbor, Nigeria CN Isibor, EI Efordili, GA Jaboro, PI Abbah West African Journal of Allied Health Sciences 2 (1), 80 - 87 , 2026 2026
Antibiogram and Plasmid Profiles of Some Bacteria Isolates From Agbo (Locally Prepared Herbal Drinks) Sold within Agbor Metropolis, Delta State GA Jaboro, JC Igborgbor, PC Chijindu, IM Oyem, CN Isibor, TE Konyeme, ... Journal of Computing, Science &Technology 4, 45-50 , 2026 2026
Pattern of Haematological Indices Among Pregnant Women at Booking in a Specialist Hospital in South-South Nigeria RN Maduka, CN Isibor Ibom Medical Journal 19 (1), 276 -284 , 2026 2026
Selected physico-chemical and polycyclic aromatic hydrocarbon (PAH) profiles of raw surface water samples and liquid herbal preparations (agbo) obtained from Agbor, mid-western … JA Grandy, IN Clement, OO Nosa, CP Chidiebere, OU James, KI Efe 2026
Unmasking Renal Cell Carcinoma: A Comprehensive Review of Histological Signatures and Subtypes AO Naiho, AC Nnamudi, CN Isibor, N Asiwe, EO Ezendiokwere, D Odah, ... Asian Oncology Research Journal 9 (1), 1-18 , 2026 2026
Bacteriological Quality and Proximate Analysis of Garri Sold in Ika Locality, Delta State Nigeria CN Isibor, E Evidence, GA Jaboro International Journal of Research 12 (8), 336 - 338 , 2025 2025
Malaria: Immune System Modulation in Asymptomatic Parasitaemia the Perpetuation of an Old Enemy – A Narrative Review. SO Onemu, CN Isibor, P Dele-Ochie Lifeline Immunology 3 (1), 1 -8 , 2025 2025
Burden of Cryptococcal Antigenemia Among Symptomatic HIV Patients In Agbor, Nigeria CN Isibor, PI Abbah, A Oguchi, E Ezie GVU Journal of Science, Health and Technology 10 (1), 114 - 117 , 2025 2025
Antibacterial Activity of Lemon Juice Extract Against Pseudomonas aeruginosa and Escherichia coli DJ Jemikalajah, CN Isibor, Q Onoharigho International Research Journal of Pharmacy and Medical Sciences 8 (1), 1-3 , 2024 2024
Bacteriological Assessment of Restaurants Environment in Abraka, South-South, Nigeria CN Isibor, DJ Jemikalajah, F Ikunbor, JC Iliaya, J. Z , Isibor, CE Nwafulugo FUPRE Journal of Scientific and Industrial Research 8 (4), 268-278 , 2024 2024
Isolation and Sensitivity Patterns of Pseudomonas aeruginosa from Nonclinical Samples CN Isibor, DJ Jemikalajah, JA Emegha, E Ezie African Journal of Biomedical Research 27 (2), 421-424 , 2024 2024
Identification of phytochemicals with inhibitory potential against beta-lactamase enzymes via computer-aided approach GC Nwokebu, AB Adesina, CN Isibor, SA Aigbepue, CC Egbo, ... Bioorganic Chemistry 145, 107238 , 2024 2024 Citations: 12
An assessment of the immune status of some stone quarry workers in Ondo state, Nigeria SO Onemu, EI Obeagu, AA Popoola, MA Osuntuyi, CN Isibor Medicine 103 (2), e36969 , 2024 2024 Citations: 7
Determination of Minimum Inhibitory Concentration of Clinical Isolates From a Hospital in South -South Nigeria C Isibor, JD Jemikalajah Journal of Computing Science & Technology 1 (1), 59 - 63 , 2024 2024
Experimental Evaluation of the Effects of Ciprofloxacin and Levofloxacin on Semen Parameters of Male Rats SO Onemu, JT Kolawole, CN Isibor, FG Ademulegun Elite Journal of Laboratory Medicine 2 (8), 23-32 , 2024 2024
Bacterial Associated with Swimming Pool Water in Benin City Nigeria AI Okoruwa, CN Isibor, AO Ukpene African Journal of Health, Safety and Environment 4 (1), 1 - 9 , 2023 2023 Citations: 1
Seasonal Responses of Flowering and Pod Setting In Cowpea (Vigna Unguiculata L. Walp) AO Ukpene, CN Isibor FUDMA JOURNAL OF SCIENCES 6 (3), 56-61 , 2022 2022 Citations: 4
Plasma Fibrinogen: A Cardiovascular Risk Biomarker in Type 2 Diabetes Mellitus Subjects M ADU, C Isibor FUDMA JOURNAL OF SCIENCES 6 (3), 100-104 , 2022 2022
Haematological Evaluation Mycobacterium tuberculosis Subjects at Central Hospital Agbor, Nigeria CN Isibor, ME Adu SJMLS 7 (1) , 2022 2022 Citations: 5
MOST CITED SCHOLAR PUBLICATIONS
Immunological response to Helicobacter pylori among healthy volunteers in Agbor, Nigeria EA Ophori, C Isibor, SO Onemu, EJ Johnny Asian Pacific Journal of Tropical Disease 1 (1), 38-40 , 2011 2011 Citations: 25
Prevalence of haemoglobin variants among the Ika ethnic nationality of Delta state C Isibor International Journal of Medicine and Biomedical Research , 2014 2014 Citations: 14
Identification of phytochemicals with inhibitory potential against beta-lactamase enzymes via computer-aided approach GC Nwokebu, AB Adesina, CN Isibor, SA Aigbepue, CC Egbo, ... Bioorganic Chemistry 145, 107238 , 2024 2024 Citations: 12
An assessment of the immune status of some stone quarry workers in Ondo state, Nigeria SO Onemu, EI Obeagu, AA Popoola, MA Osuntuyi, CN Isibor Medicine 103 (2), e36969 , 2024 2024 Citations: 7
Lymphocyte subpopulations among pregnant women in Agbor, Delta State, Nigeria OE Anthony, IN Clement Asian Pacific Journal of Tropical Disease 2 (4), 293-296 , 2012 2012 Citations: 7
Haematological Evaluation Mycobacterium tuberculosis Subjects at Central Hospital Agbor, Nigeria CN Isibor, ME Adu SJMLS 7 (1) , 2022 2022 Citations: 5
Seasonal Responses of Flowering and Pod Setting In Cowpea (Vigna Unguiculata L. Walp) AO Ukpene, CN Isibor FUDMA JOURNAL OF SCIENCES 6 (3), 56-61 , 2022 2022 Citations: 4
Prevalence of Malaria Parasitaemia and Anaemia Among Pregnant women in Warri, Nigeria CN Isibor, EU Omokaro, I Ahonkha, JA Isibor Journal of Medical Laboratory Science 12 (1), 53-58 , 2003 2003 Citations: 4
Prevalence of Mycobacterium tuberculosis in Human Immunodeficiency Virus Patients at ART Centre Agbor, Nigeria ME Adu, E Ezie, CN Isibor, DJ Jemikalajah African Journal of Cellular Pathology 4 (5), 62-65 , 2015 2015 Citations: 3
Aetiologial Spectrum of Post Operative Wound Infections in Delta State, Nigeria CN Isibor, I Ahonkhai, J Akrele Nigerian Journal of microbiology 14, 29-31 , 2000 2000 Citations: 2
Bacterial Associated with Swimming Pool Water in Benin City Nigeria AI Okoruwa, CN Isibor, AO Ukpene African Journal of Health, Safety and Environment 4 (1), 1 - 9 , 2023 2023 Citations: 1
Comparative In-Vitro Activity of Fluoroquinolones Against Clinical Bacterial Pathogens Isolated From Central Hospital Warri CN ISIBOR, I AHONKAHI Nigerian Journal of Scientific Research 21 (1), 1 - 10 , 2022 2022 Citations: 1
Evaluation of CD4+ and CD8+ lymphocyte counts in patients with tuberculosis infection. CN Isibor, SE Omoingho, EA Ophori, R Okojie, ME Adu 2021 Citations: 1
Assessment of Bacterial Contamination of Mobile Phones Used by Students in University of Delta, Agbor, Nigeria C Isibor, AJ Grandy, E Efordili, IA Patience West African Journal of Allied Health Sciences 2 (1) , 2026 2026
Public Health Implications of Bacterial Contamination of Mobile Phones Among Students at the University of Delta, Agbor, Nigeria CN Isibor, EI Efordili, GA Jaboro, PI Abbah West African Journal of Allied Health Sciences 2 (1), 80 - 87 , 2026 2026
Antibiogram and Plasmid Profiles of Some Bacteria Isolates From Agbo (Locally Prepared Herbal Drinks) Sold within Agbor Metropolis, Delta State GA Jaboro, JC Igborgbor, PC Chijindu, IM Oyem, CN Isibor, TE Konyeme, ... Journal of Computing, Science &Technology 4, 45-50 , 2026 2026
Pattern of Haematological Indices Among Pregnant Women at Booking in a Specialist Hospital in South-South Nigeria RN Maduka, CN Isibor Ibom Medical Journal 19 (1), 276 -284 , 2026 2026
Selected physico-chemical and polycyclic aromatic hydrocarbon (PAH) profiles of raw surface water samples and liquid herbal preparations (agbo) obtained from Agbor, mid-western … JA Grandy, IN Clement, OO Nosa, CP Chidiebere, OU James, KI Efe 2026
Unmasking Renal Cell Carcinoma: A Comprehensive Review of Histological Signatures and Subtypes AO Naiho, AC Nnamudi, CN Isibor, N Asiwe, EO Ezendiokwere, D Odah, ... Asian Oncology Research Journal 9 (1), 1-18 , 2026 2026
Bacteriological Quality and Proximate Analysis of Garri Sold in Ika Locality, Delta State Nigeria CN Isibor, E Evidence, GA Jaboro International Journal of Research 12 (8), 336 - 338 , 2025 2025