Professor Kamla Pathak, graduate and post graduate (Pharmaceutics) from University Institute of Pharmaceutical sciences, Panjab University, Chandigarh, India; earned her Doctorate in Pharmacy in the year 1991, from the same institute. With a teaching and research experience of more than 31 years, is currently working as Dean and Professor, Faculty of Pharmacy, Uttar Pradesh University of Medical Sciences, Etawah, India. India. She is a member of various professional bodies. Actively engaged in research on oral controlled /modulated/targeted and topical drug delivery systems has over 270 publications in journals of international and national repute. Three patents, 4 books, 21 book chapters (in international books) and more than 180 abstracts of the papers presented in various scientific forums are to her credit. Credited as reviewer of national and international journals of repute in the field of Pharmaceutics, has a h-index of 40 (Scopus) and 51 (Google scholar).
EDUCATION
PhD ( Pharmacy), M. Pharm, (Pharmaceutics),
RESEARCH, TEACHING, or OTHER INTERESTS
Pharmaceutical Science, General Pharmacology, Toxicology and Pharmaceutics
Integration of Synchronizing In Silico, In Vitro, and In Vivo Strategies for the Development of Antipsoriatic Apremilast-loaded Nanostructured Lipid Carrier Embedded in Hydrogel Nikita Patel, Aneri Desai, Bhavin Vyas, Pranav Shah, Mangrulkar Shubhada, Umekar Milind, Kamla Pathak, Mahavir Bhupal Chougule AAPS Pharmscitech, 2025 One of the major challenges in the psoriasis therapies is the systemic side effects. This research investigation intended to design, formulate, and characterize topical Apremilast (APR) nanostructured lipid carriers (NLCs) embedded hydrogel. APR-loaded NLCs were prepared using the hot melt ultrasonication technique using glyceryl monostearate (GMS) and Capmul® MCM, followed by high-speed homogenization. The entrapment and size were 85.5 ± 2.1% and 242.5 ± 3.1 nm, respectively. Using molecular docking, the interactions between APR-GMS and APR-Capmul® MCM were investigated. 32 factorial designs were used to optimize APR-loaded NLCs, employing a quality-by-design approach. The spherical shape of the nanocarriers was depicted in the SEM images of NLCs dispersion. With a regression value of 0.9745, the in vitro drug release of APR-NLCs dispersion matched the Higuchi model and demonstrated extended-release up to 28 hrs (99.0 ± 1.7%). An in vitro cellular toxicity depicted that formulation excipients had minimal effect, as cell viability was still > 80% at concentrations of up to 30 µg/mL. APR-NLC hydrogel exhibited extended release up to 36 hrs (97.1 ± 0.8%), with diffusion as a release mechanism. Since there was no significant difference observed in viscosity (cp) or % CDR throughout 24 hrs at 5°, indicate APR-NLCs hydrogel was stable in a refrigerated condition. Compared to the positive control, APR liquid, and pure drug, APR-NLCs hydrogel showed a substantial decrease in PASI score. Topical APR-loaded NLCs embedded in Hydrogel enhanced efficacy in the imiquimod-induced psoriasis in the murine model found to be non-irritating with minimal systemic side effects. The findings imply that APR-loaded NLCs embedded in Hydrogel can be used topically to treat psoriasis by focusing on the skin's outer layers.
NANOMEDICINE FOR NEURODEGENERATIVE DISORDERS: Selective Treatment Strategies Nanomedicine for Neurodegenerative Disorders Selective Treatment Strategies, 2025
Solid Oral Drug Delivery System Advances in Pharmaceutical Technology for Drug Delivery Systems Ptdds Volume 1 Recent Progress in Modern Drug Targeting Strategies, 2025
Nano Approaches Toward CNS Drug Delivery Nanomedicine for Neurodegenerative Disorders Selective Treatment Strategies, 2025
Nanotechnology in Pulmonary Drug Delivery Systems Prachi Saini, Kanika, Girish Kumar, Tarun Virmani, Kamla Pathak Advanced Drug Delivery Systems in Management of Chronic Obstructive Pulmonary Disease, 2025
Transforming cancer treatment: The potential of nanonutraceuticals Girish Kumar, Tarun Virmani, Vaishnavi Chhabra, Reshu Virmani, Kamla Pathak, Md Sayeed Akhtar, Mulazim Hussain Asim, Shumaila Arshad, Farzana Siddique, Pedro Fonte International Journal of Pharmaceutics, 2024
Bioavailability and bioequivalence Ravi Shankar, Monika Joshi, Sonal Mehrotra, Vijay Sharma, Kamla Pathak Physico Chemical Aspects of Dosage Forms and Biopharmaceutics Recent and Future Trends in Pharmaceutics Volume 2, 2024
Synbiotics in Oral Drug Delivery Girish Kumar, Tarun Virmani, Ashwani Sharma, Reshu Virmani, Kamla Pathak Synbiotics in Human Health Biology to Drug Delivery, 2024
Impact of nonconventional solvents on environment Tarun Virmani, Vaishnavi Chhabra, Girish Kumar, Ashwani Sharma, Kamla Pathak Organic Synthesis Natural Products Isolation Drug Design Industry and the Environment, 2023
Development and Characterization of Pullulan-Based Orodispersible Films of Iron Maram Suresh Gupta, Tegginamath Pramod Kumar, Dinesh Reddy, Kamla Pathak, Devegowda Vishakante Gowda, A. V. Naresh Babu, Alhussain H. Aodah, El-Sayed Khafagy, Hadil Faris Alotaibi, Amr Selim Abu Lila, Afrasim Moin, Talib Hussin Pharmaceutics, 2023
Legislation on active and intelligent packaging Shashi Kiran Misra, Kamla Pathak Green Sustainable Process for Chemical and Environmental Engineering and Science Methods for Producing Smart Packaging, 2023
Enhancement of permeability and dissolution profile of poorly permeable drug by using controlled crystallization bottom up technique Latin American Journal of Pharmacy, 2020
Development of ziprasidone nanocrystals prepared by wet media milling technique: IVIVC Latin American Journal of Pharmacy, 2020
Biopolymer from cicer arietinum, a novel bioexcipient: Its isolation, characterization and utilization in delivery of nanosized lamotrigine Latin American Journal of Pharmacy, 2020
Enhancement of dissolution of felodipine; A thermostable compound by hot-melt extrusion solid dispersion approach International Journal of Pharmaceutical Sciences Review and Research, 2016
Norfloxacin loaded pH triggered nanoparticulate in-situ gel for extraocular bacterial infections: Optimization, ocular irritancy and corneal toxicity Iranian Journal of Pharmaceutical Research, 2016
Formulation, optimization and characterization of ziprasidone nanocrystals prepared by media milling technique International Journal of Pharmacy and Pharmaceutical Sciences, 2015
Solid dispersion adsorbates - A novel method for enhancement of dissolution rates of Felodipine International Journal of Pharmaceutical Sciences Review and Research, 2013
Kyron T-114 as an effective precursor for development of fixed dose combination orodispersible formulation using taste masked resinate International Journal of Drug Development and Research, 2013
Formulation and evaluation of taste masked rapid release tablets of sumatriptan succinate International Journal of Pharmacy and Pharmaceutical Sciences, 2012
Development and statistical optimization of buccoadhesive films of amiloride hydrochloride: In-vitro and ex-vivo evaluation Indian Journal of Pharmaceutical Education and Research, 2012
Enhancement of solubility and dissolution rate of a poorly water soluble drug using single and double hydrophilization approach International Journal of Pharmacy and Pharmaceutical Sciences, 2012
Preparation, characterization and pharmacodynamic evaluation of fused dispersions of Simvastatin using PEO-PPO block copolymer Iranian Journal of Pharmaceutical Research, 2012
Development and validation of a novel spectrophotometric analytical method for the determination of olmesartan medoxomil in pharmaceutical formulations International Journal of Pharmacy and Pharmaceutical Sciences, 2011
Evaluation of the kinetics and mechanism of drug release from econazole nitrate nanosponge loaded carbapol hydrogel Indian Journal of Pharmaceutical Education and Research, 2011
Poly (HEMA) and poly (EGMA) gels of meloxicam: An assessment of polymerization techniques on the pharmacotechnical properties of the gels Indian Journal of Pharmaceutical Education and Research, 2010
Effect of milling on correlation between interquartile coefficient of skewness and coefficient of kurtosis in pharmaceutical powders - II Indian Journal of Pharmaceutical Education and Research, 2009
Passage-delaying microbeads for controlled delivery of loratadine PDA Journal of Pharmaceutical Science and Technology, 2008
Correlation between interquartile coefficient of skewness and coefficient of kurtosis in pharmaceutical powders Indian Journal of Pharmaceutical Education and Research, 2008
Preformulative assessment of preformed complexes of gemfibrozil, with cyclodextrins PDA Journal of Pharmaceutical Science and Technology, 2008
Correlation between interquartile coefficient of skewness and coefficient of kurtosis in pharmaceutical powders Indian Journal of Pharmaceutical Education and Research, 2008
Use of asymmetric capsular system for osmotic dosage form: A review Pharma Times, 2007
In situ-formed asymmetric membrane capsule for osmotic release of poorly water-soluble drug PDA Journal of Pharmaceutical Science and Technology, 2007
Physicochemical characterization and dissolution enhancement of aceclofenac-hydroxypropyl β-cyclodextrin binary systems PDA Journal of Pharmaceutical Science and Technology, 2006
A28-06 Sex Differences in Acute Pulmonary Embolism Outcomes Among African American Patients With Sickle Cell Disease: A National Estimate N Singh, A Ramesh, K Pathak, D Pathak, K Savani, KS Dhaliwal, ... American Journal of Respiratory and Critical Care Medicine 212 (Supplement_1 … , 2026 2026
C54-21 Demographic and Mortality Differences Between Intensive Care and Non-intensive Care Admissions for Pseudomonas Sepsis in Chronic Lymphocytic Leukemia Patients A Ramesh, N Singh, K Savani, D Pathak, K Pathak, KS Dhaliwal, ... American Journal of Respiratory and Critical Care Medicine 212 (Supplement_1 … , 2026 2026
C27-12 Pneumocystis Jirovecii Pneumonia Among Cancer Patients: Comparing Outcomes Between Solid Tumors and Hematologic Malignancies N Singh, A Ramesh, K Savani, K Pathak, D Pathak, KS Dhaliwal, ... American Journal of Respiratory and Critical Care Medicine 212 (Supplement_1 … , 2026 2026
B80-4-40 Myth or Reality: The July Effect on Robotic-assisted Thoracoscopic Lung Resection in Malignant Lung Neoplasms at Urban Teaching Centers A Ramesh, N Singh, K Savani, K Pathak, D Pathak, KS Dhaliwal, ... American Journal of Respiratory and Critical Care Medicine 212 (Supplement_1 … , 2026 2026
A67-11 Catheter-Directed Thrombolysis in Recurrent Versus First-Time Pulmonary Embolism: Comparing Complications, Mortality, and Readmissions N Singh, B Dhillon, K Pathak, D Pathak, K Savani, KS Dhaliwal, ... American Journal of Respiratory and Critical Care Medicine 212 (Supplement_1 … , 2026 2026
B42-23 Clinical Profile and Healthcare Burden of Isolated Pulmonary Sarcoidosis Versus Combined Pulmonary-Cardiac Sarcoidosis: A Nationwide Analysis N Singh, K Pathak, K Savani, D Pathak, KS Dhaliwal, K Ramphul American Journal of Respiratory and Critical Care Medicine 212 (Supplement_1 … , 2026 2026
Advantages of targeted nanomedicine in cancer treatment SK Misra, K Pathak Two Sides of Nanovaccines and Nanomedicines in Cancer Treatments, 95-113 , 2026 2026
Green nanotechnology for the management of chronic obstructive pulmonary disease: Concept, principle, prospectives and challenges N Sharma, PC Gupta, K Pathak Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease … , 2026 2026
Exosomes and Other Extracellular Vesicles in Gene Therapy and Personalized Care G Mahalawat, T Virmani, G Kumar, A Sharma, P Saini, K Mangla, ... Clinical Potential of Exosomes, 603-644 , 2026 2026
Lipid Based Nanocarriers for Drug Delivery G Kumar, T Virmani, R Virmani, K Pathak Nanotechnologies for Drug Delivery and Biopharmaceutical Development, 79-109 , 2025 2025 Citations: 1
Nanoencapsulation of Bioactive Compounds M Kumar, T Virmani, K Pathak Nanotechnologies for Drug Delivery and Biopharmaceutical Development, 363-387 , 2025 2025
Retraction Note: Nanosilver-functionalized polysaccharides as a platform for wound dressing S Mohan, P Wal, K Pathak, M Khandai, T Behl, HA Alhazmi, G Khuwaja, ... Environmental Science and Pollution Research 32 (44), 25434-25434 , 2025 2025
Nanotechnology in Pulmonary Drug Delivery Systems P Saini, G Kumar, T Virmani, K Pathak Advanced Drug Delivery Systems in Management of Chronic Obstructive … , 2025 2025
Solid Oral Drug Delivery System V Chhabra, T Virmani, G Kumar, K Pathak Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), 1-25 , 2025 2025
Nano Approaches Toward CNS Drug Delivery A Sharma, A Sharma, G Kumar, T Virmani, K Pathak Nanomedicine for Neurodegenerative Disorders, 187-231 , 2025 2025 Citations: 1
Integration of Synchronizing In Silico , In Vitro, and In Vivo Strategies for the Development of Antipsoriatic Apremilast-loaded Nanostructured Lipid Carrier … N Patel, A Desai, B Vyas, P Shah, M Shubhada, U Milind, K Pathak, ... AAPS PharmSciTech 26 (5), 115 , 2025 2025 Citations: 5
Application of carbohydrates as renewable feedstocks for the synthesis of bioactive compounds SK Misra, A Kumar, S Singh, K Pathak Carbohydrates in Chemistry and Biology: Decorated Compounds, Bioconjugates … , 2025 2025
Transforming cancer treatment: The potential of nanonutraceuticals G Kumar, T Virmani, V Chhabra, R Virmani, K Pathak, MS Akhtar, ... International Journal of Pharmaceutics 667, 124919 , 2024 2024 Citations: 14
Nanovaccines for Mucosal Immunity SK Misra, A Kapoor, K Pathak Nanocarrier Vaccines: Biopharmaceutics‐Based Fast Track Development, 367-404 , 2024 2024
Exploration of chitosan and its modified derivatives as vaccine adjuvant: A review G Kumar, T Virmani, SK Misra, A Sharma, K Pathak Carbohydrate Polymer Technologies and Applications 8, 100537 , 2024 2024 Citations: 27
MOST CITED SCHOLAR PUBLICATIONS
Fast dissolving oral films: an innovative drug delivery system and dosage form A Arya, A Chandra, V Sharma, K Pathak Int J ChemTech Res 2 (1), 576-83 , 2010 2010 Citations: 627
Intranasal nanoemulsion based brain targeting drug delivery system of risperidone M Kumar, A Misra, AK Babbar, AK Mishra, P Mishra, K Pathak International Journal of Pharmaceutics 358 (1-2), 285-291 , 2008 2008 Citations: 601
Therapeutic and cosmeceutical potential of ethosomes: An overview P Verma, K Pathak Journal of Advanced Pharmaceutical Technology & Research 1 (3), 274-282 , 2010 2010 Citations: 506
Comprehensive review on current developments of quinoline-based anticancer agents S Jain, V Chandra, PK Jain, K Pathak, D Pathak, A Vaidya Arabian Journal of Chemistry 12 (8), 4920-4946 , 2019 2019 Citations: 436
Flavonoids as medicinal agents-recent advances. D Pathak, K Pathak, AK Singla Fitoterapia 62 (5), 371-389 , 1991 1991 Citations: 357
Nanostructured lipid carrier versus solid lipid nanoparticles of simvastatin: comparative analysis of characteristics, pharmacokinetics and tissue uptake R Tiwari, K Pathak International Journal of Pharmaceutics 415 (1-2), 232-243 , 2011 2011 Citations: 325
Porous carriers for controlled/modulated drug delivery G Ahuja, K Pathak Indian Journal of Pharmaceutical Sciences 71 (6), 599 , 2009 2009 Citations: 295
Nanosized ethanolic vesicles loaded with econazole nitrate for the treatment of deep fungal infections through topical gel formulation P Verma, K Pathak Nanomedicine: Nanotechnology, Biology and Medicine 8 (4), 489-496 , 2012 2012 Citations: 288
Development and Statistical Optimization of Solid Lipid Nanoparticles of Simvastatin by Using 2 3 Full-Factorial Design M Shah, K Pathak AAPS pharmscitech 11 (2), 489-496 , 2010 2010 Citations: 272
A review on mucoadhesive polymer used in nasal drug delivery system M Chaturvedi, M Kumar, K Pathak Journal of Advanced Pharmaceutical Technology & Research 2 (4), 215-222 , 2011 2011 Citations: 264
Mucoadhesive nanoemulsion-based intranasal drug delivery system of olanzapine for brain targeting M Kumar, A Misra, AK Mishra, P Mishra, K Pathak Journal of Drug Targeting 16 (10), 806-814 , 2008 2008 Citations: 246
Oral bioavailability: issues and solutions via nanoformulations K Pathak, S Raghuvanshi Clinical Pharmacokinetics 54 (4), 325-357 , 2015 2015 Citations: 240
Evaluation of the kinetics and mechanism of drug release from econazole nitrate nanosponge loaded carbapol hydrogel R Sharma, RB Walker, K Pathak Indian Journal of Pharmaceutical Education and Research 45 (1), 25-31 , 2011 2011 Citations: 205
Polymeric nanosponges as an alternative carrier for improved retention of econazole nitrate onto the skin through topical hydrogel formulation R Sharma, K Pathak Pharmaceutical Development and Technology 16 (4), 367-376 , 2011 2011 Citations: 190
Physicochemical and physiological considerations for efficient nose-to-brain targeting S Bahadur, K Pathak Expert opinion on drug delivery 9 (1), 19-31 , 2012 2012 Citations: 187
Intranasal nanoemulsions for direct nose-to-brain delivery of actives for CNS disorders S Bahadur, DM Pardhi, J Rautio, JM Rosenholm, K Pathak Pharmaceutics 12 (12), 1230 , 2020 2020 Citations: 185
Artificial intelligence‐based data‐driven strategy to accelerate research, development, and clinical trials of COVID vaccine A Sharma, T Virmani, V Pathak, A Sharma, K Pathak, G Kumar, D Pathak BioMed research international 2022 (1), 7205241 , 2022 2022 Citations: 175
Formulation and characterization of nanoemulsion-based drug delivery system of risperidone M Kumar, K Pathak, A Misra Drug development and industrial pharmacy 35 (4), 387-395 , 2009 2009 Citations: 171
Phytoconstituents of Euphorbia species. AK Singla, KP Kamla Pathak Fitoterapia 41 (6), 483-516 , 1990 1990 Citations: 161
Biomedical applications of quaternized chitosan K Pathak, SK Misra, A Sehgal, S Singh, S Bungau, A Najda, R Gruszecki, ... Polymers 13 (15), 2514 , 2021 2021 Citations: 153