Synthesis, studies and stereo chemical investigations on nitrogen heterocycles such as piperidinones, pyrazoles, bispidines, diazaadamantanes, quinolines, isoquinolines, coumarins, through NMR, X-ray diffraction studies.
228
Scopus Publications
3096
Scholar Citations
26
Scholar h-index
86
Scholar i10-index
Scopus Publications
Synthesis, crystal, electronic studies, in silico modelling, and ADMET profiling of (E)-5-(diethylamino)-2-(((1,3-diphenyl-1H-pyrazol-5-yl)imino)methyl)phenol (DDPMP): a promising anti-cancer agent U. Mithra, Rebecca Susan Philip, S. Sarveswari, V. Vijayakumar Results in Chemistry, 2026 A pyrazole-based imine compound, DDPMP , has been designed using an efficient and simple method. The synthesised compound has been crystallised, and its structure has been confirmed using several techniques, including FTIR, 1 H and 13 C NMR, DEPT-135, H-H COSY, HSQC, and HMBC. The mass of the compound was verified through high-resolution mass spectrometry (HRMS), and both absorption and emission spectra were recorded. Solvatochromism studies reveal that DDPMP exhibits a bathochromic shift. Geometrical optimisation and an analysis of the electronic properties, along with electrostatic potential mapping, were performed using Density Functional Theory (DFT) and Time-Dependent DFT (TD-DFT). Furthermore, DDPMP demonstrates excellent anticancer activity, as confirmed through in-silico studies that compared it with three PDB structures: 1SA0, 5XIW, and 4O2B. Consequently, DDPMP serves as a promising tubulin inhibitor. • Synthesis and spectroscopic confirmation of (E)-5-(diethylamino)-2-(((1,3-diphenyl-1H-pyrazol-5-yl)imino)methyl)phenol (DDPMP), via a conventional method. • The structural verification of DDPMP was conducted using various NMR techniques along with the single-crystal XRD. • DFT calculations were performed to analyse spectral properties, energy differences between the excited states, and electron density. • In-silico tests with PDB structures: 1SA0, 5XIW, and 4O2B assessed the binding affinity of the DDPMP as a promising tubulin inhibitor. • In silico studies reveal DDPMP can serve as an excellent anticancer agent.
Synthesis, crystal structure analysis, Hirshfeld surface study, and DFT investigation of amino-substituted bis(cyclohexanone) derivatives Vijayabharathi Sundharaj, Nagesh Dhanaji Chavan, Sundaramoorthy Sarveswari, Arup Sinha, Vijayaparthasarathi Vijayakumar Results in Chemistry, 2026 Two amino-substituted bis(cyclohexenone) derivatives were synthesized using dimedone and substituted aldehydes. The crystal structure analysis confirmed the molecular geometry and revealed the presence of intermolecular interactions responsible for the stability of the compounds in the solid state. Theoretical studies showed that the N -methyl derivative has a HOMO–LUMO energy gap of 3.51 eV, indicating good stability and moderate reactivity. Molecular electrostatic potential analysis identified the reactive sites within the molecules. Hirshfeld surface analysis indicated that H···H and O···H interactions play a major role in crystal packing. Molecular docking studies against the target protein (PDB ID: 6O0K ) showed that both compounds exhibit good binding interactions, with the N -phenyl derivative showing the highest binding affinity of −11.03 kcal/mol. These results provide useful insights into the structural, electronic, and biological properties of the synthesized compounds. • Synthesis of 2,2′-((4-(dialkyl/arylamino)phenyl) methylene)bis(3-hydroxy-5,5-dimethylcyclohex-2-en-1-ones). • X-ray crystallographic investigations, MEP, FMO and Hirshfeld surface analysis performed.
Synthesis, DFT study, and molecular docking of novel quinoline-4-carboxamide derivatives as potential oxireductase inhibitors Sachin Krishna Meghe, Vijayaparthasarathi Vijayakumar Results in Chemistry, 2026 A series of novel quinoline-4-carboxamide derivatives was designed, synthesised, and assessed for their potential to inhibit key oxidoreductase proteins implicated in advancement of cancer progression. To understand the electronic properties and reactivity of the synthesised molecules, density functional theory (DFT) calculations were performed at the B3LYP/631G(d,p) level. Key global reactivity descriptors, including the energy of the highest occupied molecular orbital (HOMO), the energy of the lowest unoccupied molecular orbital (LUMO), energy gap(ΔE), ionisation potential (I), electronic affinity (A), electronegativity (χ), chemical potential (μ), hardness (H), softness (S), electrophilicity (ω) were calculated. Subsequently, molecular docking studies were conducted to determine the binding affinities and interaction modes of the synthesised quinoline-4-carboxamides within the active sites of target oxidoreductase proteins, namely dihydroorotate dehydrogenase (PDB ID. 3U2O ), cyclooxygenase-2 (PDB ID. 5IKT ), and peroxiredoxin-2 (PDB ID. 5IJT ). The combined DFT and docking data provide a strong rationale for further biological evaluation and optimization of these compound as potential anticancer agents. • A series of novel quinoline-4-carboxamides was synthesised, explored their potential as anticancer agents. • DFT studies to evaluate FMO, MEP, and global reactivity descriptors. • Molecular docking conducted against key targets: peroxiredoxin-2 (5IJT), cyclooxygenase-2 (5IKT), and Dihydroorotate Dehydrogenase (3U2O). • Studies revealed strong hydrogen bonding and hydrophobic interactions, particularly for derivatives bearing electron-withdrawing substituents, indicating enhanced target specificity. • The combined DFT and docking analyses revealed that quinoline-4-carboxamide scaffolds possess promising pharmacological profiles.
A review on biologically important benzimidazole derivatives Vijayabharathi Sundharaj, V. Vijayakumar, S. Sarveswari Results in Chemistry, 2026 Chemists have long been interested in the synthesis of benzimidazole derivatives, resulting in numerous studies on this heterocyclic compound. Its exceptional therapeutic efficacy in treating diseases has attracted further attention. The wide-range use of pharmaceuticals to address biological processes and diseases underscores the need for more potent treatments. Benzimidazole compounds exhibit diverse properties with different substitutions and modifications in the side chain, including anticancer, antiviral, antimalarial, and anti-inflammatory effects. This article provides an overview of recent research on benzimidazole derivatives and their biological activities.
Synthesis of a highly selective indazole-based chemosensor for detecting the lethal CN− and its real-time applications in water samples M.S. Sunitha, V. Vijayakumar, K. Parthasarathy, S. Sarveswari Results in Chemistry, 2026 An indazole derivative, VS, was synthesized from benzo[ d ]thiazol-2-amine and 1 H -indazole-3-carboxylic acid and was found to detect the cyanide (CN − ) ion selectively. The sensor characteristics of VS were studied using UV-absorption studies in a DMSO medium. The probe VS was discovered to display a colorimetric response, from colourless to yellow colour when it reacts with the CN − ion. 1 H NMR studies were utilized to ascertain the recognition mechanism, which revealed the CN − ion-assisted deprotonation of two-N-H protons of VS. The developed probe VS was found to be sensitive towards CN − ion with a detection limit of 8.9 × 10 −6 M, and B–H plot revealed a binding constant of 9.3 × 10 −7 M. The CN − ion observed to bind with the probe VS in a 1:2 stoichiometry was confirmed by using Job's plot, and the treatment with trifluoroacetic acid makes probe VS recyclable, and also discovered that VS is capable of sensing the CN − ion in cashew fruit and drinking water samples. The probe VS was demonstrated as a colorimetric test kit using cotton swabs.
Synthesis and in silico studies of quinoline appended acridine via conventional and green methods: photophysical analysis of novel fluorophore for picric acid detection using a ‘turn-off' fluorescence approach Rebecca Susan Philip, V. Vijayakumar BMC Chemistry, 2025 Abstract A series of novel 4-(9-phenyl-1,2,3,4-tetrahydroacridin-2-yl)cyclohexan-1-ones and their dimers were synthesized using an efficient one-pot method with Deep Eutectic Solvents (DESs), alongside microwave-assisted and conventional techniques. Using less toxic and inexpensive DESs enhance sustainability in producing desired products. Green metrics calculations indicate a high level of greenness in the synthesis process. FT-IR, NMR, and HRMS characterized the compounds. In-silico tests involving Bovine Serum Albumin (BSA) assessed the binding affinity of the compounds toward various drugs. Furthermore, DFT studies explored theoretical spectral calculations, energy differences, and electron cloud density. Notably, among the derivatives, the fluorophore 4-(7-amino-9-phenyl-1,2,3,4-tetrahydroacridin-2-yl)cyclohexan-1-one ( 3e ) can specifically detect 2,4,6-trinitrophenol (Picric acid, PA), a fatal nitro explosive. Photophysical studies confirmed 3e 's ability as a “turn-off” fluorescence chemosensor for PA with a detection limit of 1.766 × 10 –9 M and a binding stoichiometric ratio of 1:1 between the probe and analyte. Structural confirmation of the probe was achieved through single-crystal XRD.
Synthesis of novel sulphonamide derivatives from tunable quinolines with computational studies Nagesh Dhanaji Chavan, S. Sarveswari, V. Vijayakumar Scientific Reports, 2025 The synthesis of new quinoline-sulphonamide derivatives was accomplished through a meticulous five-step molecular assembly utilizing Suzuki, acid–amine cross-coupling reactions and N-alkylation. The integrity of each derivative was thoroughly confirmed via comprehensive spectroscopic analyses, including 1H and 13C NMR, DEPT-135, 1H-1H COSY, HSQC NMR and HRMS techniques. Subsequently, the absorbance and emission spectra of the newly synthesized derivatives were thoroughly investigated. Absorbance spectra were determined to be restricted within the range of 337 nm to 341.73 nm, with compound 10j exhibiting the maximum wavelength of 341.73 nm; conversely, emission spectra were uniformly detected within the range of 411.70 nm to 429.90 nm upon excitation at 340 nm, with compound 10f demonstrating the highest wavelength of 429.90 nm. Notably, these fluorophores displayed impressive characteristics, with high intensity and significant molar extinction coefficients; quantum yield ranging from 0.015 to 0.558 along with the highest stokes shifts in 10h compound (0.6237 × 10–4) in acetonitrile solvent. Additionally, compound 10p showed strong binding affinity and favorable pharmacokinetic properties through molecular docking studies and ADMET calculations. The electronic structure of the molecules was elucidated using techniques such as density functional theory (DFT) and molecular electrostatic potential (MEP) mapping. Additionally, the calculated global reactivity parameters provided valuable insights. Compound 10p exhibited a distinctly low energy gap compared to other compounds, demonstrating its exceptional properties. The comparison between experimental and theoretical UV–vis spectra with major contribution transition in percentage also showcased the remarkable consistency and quality of the synthesized derivatives, highlighting the significant potential of this work in the field of fluorophore and biological application.
A benzylidene-amine scaffold as a colourimetric sensor for picric acid: computational studies and real-time applications using matchstick head powder Viswanathan Hemalatha, Sundaramoorthy Sarveswari, Vijayaparthasarathi Vijayakumar BMC Chemistry, 2025 A series of simple and cost-effective benzylidene-amine appended probes (E)-4-((4-(allyloxy) benzylidene)amino)-N-phenyl aniline ( L-1 ), (E)-N-phenyl-4-((2,3,4-trimethoxybenzylidene) amino)aniline ( L-2 ), and (E)-4-((2-nitrobenzylidene)amino)-N-phenyl aniline ( L-3 ) have been developed for the rapid detection of picric acid (PA) and explored for the same. Notably, L-3 showed no changes in its UV spectrum or colour upon interaction with PA. In contrast, when PA was added to L-1 and L-2 , there were significant changes in absorption, resulting in distinct colour changes. Mole fraction analysis indicated a 1:1 ratio between the probes and PA. The detection limits for PA were impressively low, measuring 4.37 × 10 − 7 M for L-1 and 4.56 × 10 − 6 M for L-2 . This demonstrates the effectiveness of these probes in detecting PA, even at very low concentrations. Importantly, this work marks the first application of benzylidene-amine probes for the detection of PA. The sensing studies were supported by theoretical analyses and calculations, which confirmed the selective detection of PA using matchstick head powder (MSPS) and a test kit based on paper strips. Additionally, smartphone-assisted detection using an RGB tool was successfully demonstrated. Graphical abstract
Novel benzimidazole-1, 3, 4-thiadiazole derivatives as casein kinase-2 inhibitors: synthesis, in vitro and in silico investigations N. Senthilkumar, S. Sarveswari, Prafulla Choudhari, Somdatta Chaudhari, Imadul Islam, Yasinalli Tamboli, V. Vijayakumar BMC Chemistry, 2025 A new set of benzimidazole-thiadiazole derivatives has been designed and synthesized using 2-(chloromethyl)-1H-benzo[d]imidazole (1). Compounds 4a-m were achieved by amide bond formation using acid chlorides and pyridine in 1, 2-dichloroethane. The newly synthesized compounds were characterized and subjected to cytotoxicity studies against HeLa cells. Compounds 4c, 4 d, and 4e exhibited good inhibitory activity with IC50 values of 15, 25, and 25 µM, respectively. Molecular docking studies were performed to elucidate the binding interactions of compounds 4c and 4e with human Casein kinase-2 (CK2). Compound 4c exhibited maximum cytotoxicity against HeLa cells with the lowest binding energy values of -8.61 kcal/mol towards CK2. Compound 4c underwent molecular dynamics (MD) simulations to assess their stability and interactions within the active site. Density functional theory (DFT) calculations also provided insights into the synthesised compounds' electronic structure, reactivity, and charge distribution. Graphical Abstract
Production of Biodiesel from Soybean Oil in Less Time and at Low Temperature Rajan Choudhary, Anuj Kumar, Vijay Nag Ellapani, Baruah Trinayan, Muruganandam Loganathan, Lakshmi Ravy, Vijayakumar Vijayaparthasarathi, Amit Mahindrakar Baburao, Subramaniam Shanthakumar, Deepalekshmi Ponnamma, Kishor Kumar Sadasivuni, Sasikumar Swamiappan Asian Journal of Chemistry, 2022
Highly efficient multi component synthesis of xanthenes catalyzed by hydroxyapatite Journal of the Indian Chemical Society, 2015
Phytochemical and antimicrobial studies of green leafy vegetables and its enhanced bioactive properties upon fortification with probiotic Lactobacilli acidophilus Journal of the Indian Chemical Society, 2015
Synthesis and antibacterial screening of 3-(4,5-dihydro-5-aryl-lH-pyrazol-3-yl)-4-hydroxyquinolin-2(1H)-ones International Journal of Chemtech Research, 2015
3-Ethyl-4-methyl-1H-pyrazol-2-ium-5-olate R. S. Rathore, T. Narasimhamurthy, R. Venkat Ragavan, V. Vijayakumar, S. Sarveswari Acta Crystallographica Section E Structure Reports Online, 2011
1,3-Dimethyl-4-phenylsulfanyl-1H-pyrazol-5-ol Tara Shahani, Hoong-Kun Fun, R. Venkat Ragavan, V. Vijayakumar, S. Sarveswari Acta Crystallographica Section E Structure Reports Online, 2011
(E)-4-(1,3-Benzodioxol-5-yl)but-3-en-2-one S. Sarveswari, V. Vijayakumar, Priya Susan Mathew, Rafael Mendoza-Meroño, Santiago García-Granda Acta Crystallographica Section E Structure Reports Online, 2011
5-Ethyl-4-phenyl-1H-pyrazol-3(2H)-one Wan-Sin Loh, Hoong-Kun Fun, R. Venkat Ragavan, V. Vijayakumar, M. Venkatesh Acta Crystallographica Section E Structure Reports Online, 2011
3-Isobutyl-4-phenylsulfanyl-1H-pyrazol-5-ol Tara Shahani, Hoong-Kun Fun, R. Venkat Ragavan, V. Vijayakumar, S. Sarveswari Acta Crystallographica Section E Structure Reports Online, 2011
Etidronic acid catalyzed synthesis of 1,4-dihydropyridines Indian Journal of Heterocyclic Chemistry, 2011
4-methyl-5-phenyl-1H-pyrazol-3(2H)-one Wan-Sin Loh, Hoong-Kun Fun, R. Venkat Ragavan, V. Vijayakumar, S. Sarveswari Acta Crystallographica Section E Structure Reports Online, 2011
4-Methyl-5-phenyl-1H-pyrazol-3-ol Tara Shahani, Hoong-Kun Fun, R. Venkat Ragavan, V. Vijayakumar, S. Sarveswari Acta Crystallographica Section E Structure Reports Online, 2010
5-Ethyl-4-methyl-1H-pyrazol-3(2H)-one Tara Shahani, Hoong-Kun Fun, R. Venkat Ragavan, V. Vijayakumar, S. Sarveswari Acta Crystallographica Section E Structure Reports Online, 2010
5-Pentyl-4-phenylsulfonyl-1H-pyrazol-3-ol Tara Shahani, Hoong-Kun Fun, R. Venkat Ragavan, V. Vijayakumar, S. Sarveswari Acta Crystallographica Section E Structure Reports Online, 2010
N,N′-Bis(4-fluorophenyl)urea Wan-Sin Loh, Hoong-Kun Fun, S. Sarveswari, V. Vijayakumar, R. Venkat Ragavan Acta Crystallographica Section E Structure Reports Online, 2010
(E)-N-Benzylidene-4H-1,2,4-triazol-4-amine M. Thenmozhi, T. Kavitha, B. Palakshi Reddy, V. Vijayakumar, M. N. Ponnuswamy Acta Crystallographica Section E Structure Reports Online, 2010
(E)-1,1,4,4-Tetraphenylbut-2-yne-1,4-diol J. Kalyana Sundar, K. Mohan Kumar, V. Vijayakumar, J. Suresh, S. Natarajan, P. L. Nilantha Lakshman Acta Crystallographica Section E Structure Reports Online, 2010
Ethyl 2-acetyl-3-(4-bromoanilino)butanoate D. Ravi Kishore Reddy, V.Vijayakumar, J. Suresh, T. Narasimhamurthy, P. L. Nilantha Lakshman Acta Crystallographica Section E Structure Reports Online, 2010
3-Acetyl-6-chloro-4-phenylquinolin-2(1H)-one J. Kalyana Sundar, S. Natarajan, S. Sarveswari, V. Vijayakumar, P. L. Nilantha Lakshman Acta Crystallographica Section E Structure Reports Online, 2010
1,1′-(p-Phenylenedimethylene)dipiperidin-4-one V. Vijayakumar, K. Rajesh, J. Suresh, T. Narasimhamurthy, P. L. Nilantha Lakshman Acta Crystallographica Section E Structure Reports Online, 2010
5-Methoxymethyl-4-phenoxy-1Hpyrazol-3-ol Tara Shahani, Hoong-Kun Fun, R. Venkat Ragavan, V. Vijayakumar, S. Sarveswari Acta Crystallographica Section E Structure Reports Online, 2009
Ethyl 2-acetyl-3-(4-chloroanilino)- butanoate K. Rajesh, V. Vijayakumar, T. Narasimhamurthy, J. Suresh, P. L. Nilantha Lakshman Acta Crystallographica Section E Structure Reports Online, 2009
4-Azido-2-chloro-6-methyl-quinoline S. Natarajan, K. Rajesh, V. Vijayakumar, J. Suresh, P. L. Nilantha Lakshman Acta Crystallographica Section E Structure Reports Online, 2009
Synthesis and spectral studies of 1-phenyl-4-aryl/alkylaminopyrazolo 3,4-d pyrimidines Indian Journal of Heterocyclic Chemistry, 2009
Screening of antimicrobial activity of 2,4,6,8-tetraaryl-3,7-diazabicyclo [3.3.1] nonan-9-one and its derivatives Indian Journal of Heterocyclic Chemistry, 2007
Ethyl 2-acetyl-3-anilinobutanoate S. Priya, S. Sinha, V. Vijayakumar, T. Narasimhamurthy, T. Vijay, R. S. Rathore Acta Crystallographica Section E Structure Reports Online, 2006
Acridinone-Sulfonamide Hybrids: Synthesis, photophysical properties, DFT Analysis, and Antiviral Docking Against Adenovirus S Balamurugan, V Vijayakumar 2026
A review on biologically important benzimidazole derivatives V Sundharaj, V Vijayakumar, S Sarveswari Results in Chemistry, 103042 , 2026 2026 Citations: 4
Catalyst-Assisted Synthesis of Benzimidazole Derivatives: Recent Advances and Mechanistic Insights V Sundharaj, S Mohanraj, S Sarveswari, V Vijayakumar Topics in Current Chemistry 384 (1), 5 , 2026 2026 Citations: 3
A green multicomponent approach for the synthesis of 4-quinoline carboxylic acid via modified Doebner hydrogen transfer reaction SK Meghe, V Vijayakumar Green Chemistry Letters and Reviews 18 (1), 2525112 , 2025 2025 Citations: 1
Synthesis of a highly selective indazole-based chemosensor for detecting the lethal CN− and its real-time applications in water samples MS Sunitha, V Vijayakumar, K Parthasarathy, S Sarveswari Results in Chemistry, 102927 , 2025 2025 Citations: 1
A benzylidene-amine scaffold as a colourimetric sensor for picric acid: computational studies and real-time applications using matchstick head powder V Hemalatha, S Sarveswari, V Vijayakumar BMC chemistry 19 (1), 310 , 2025 2025 Citations: 1
Organic chemosensors: A comprehensive review of lead, cadmium, and arsenic ion detection strategies AA Ahmed, N Mohan, V Vijayakumar, S Sarveswari Results in Chemistry, 102823 , 2025 2025 Citations: 1
A Captivating Review on Organic Chemosensors with Imidazole Core for Cation and Anion Detection KM Gayathri, R Joseph, V Vijayakumar, S Sarveswari ChemistrySelect 10 (37), e05014 , 2025 2025 Citations: 3
A Quinoline Appended Isonicotino Hydrazide‐Based Colorimetric Chemosensor for Selective Detection of Cyanide Ion in Real Samples MS Sunitha, V Vijayakumar, N Lohitha, S Sarveswari ChemistrySelect 10 (33), e02833 , 2025 2025
Microwave‐Assisted Rapid and Efficient Synthesis of Novel Indazole‐Based 1, 3, 4‐Oxadiazole Derivatives with Molecular Docking, ADME, and DFT Studies B Gopi, V Vijayakumar Asian Journal of Organic Chemistry 14 (8), e00111 , 2025 2025
Novel benzimidazole-1, 3, 4-thiadiazole derivatives as casein kinase-2 inhibitors: synthesis, in vitro and in silico investigations N Senthilkumar, S Sarveswari, P Choudhari, S Chaudhari, I Islam, ... BMC chemistry 19 (1), 161 , 2025 2025 Citations: 4
Synthesis of Quinoline-Dihydropyrimidines: A Synergistic Green Approach Using Magnetically Recoverable Catalysts in Aqueous Medium A Sharma, QY Tamboli, ND Chavan, L Jyothish Kumar, S Sarveswari, ... Catalysis Letters 155 (6), 195 , 2025 2025
Synthesis and in silico studies of quinoline appended acridine via conventional and green methods: photophysical analysis of novel fluorophore for picric acid detection using a … RS Philip, V Vijayakumar BMC chemistry 19 (1), 93 , 2025 2025 Citations: 2
Synthesis of novel sulphonamide derivatives from tunable quinolines with computational studies ND Chavan, S Sarveswari, V Vijayakumar Scientific Reports 15 (1), 10972 , 2025 2025 Citations: 6
A Comprehensive Investigation of Diverse Synthetic Methodologies for Constructing Quinoline Frameworks: A Critical Overview ND Chavan, B Shanmugavel, Y Tamboli, V Vijayakumar ChemistrySelect 10 (10), e202500851 , 2025 2025 Citations: 6
Marine Actinobacteria mediated titanium dioxide nanoparticle synthesis and its application towards synthesis of Quinolines L Karthik, G Kumar, BP Reddy, A Vishnukirthi, J Venkatesan, SK Kim, ... Indian Journal of Microbiology 65 (1), 529-537 , 2025 2025 Citations: 1
Palladium catalyzed carbon-carbon bond formation on tunable quinolines with DFT study ND Chavan, V Vijayakumar Journal of Molecular Structure 1321, 139739 , 2025 2025 Citations: 8
Quinoline derivatives' biological interest for anti-malarial and anti-cancer activities: an overview ND Chavan, S Sarveswari, V Vijayakumar RSC advances 15 (37), 30576-30604 , 2025 2025 Citations: 26
A highly selective and sensitive quinoline-based fluorescent turn-off chemosensor for the detection of picric acid S Sudharsan, V Hemalatha, S Sarveswari, V Vijayakumar Journal of Molecular Structure 1317, 139087 , 2024 2024 Citations: 10
Indole-imidazole hybrid Schiff base for the selective detection of the explosive picric acid via fluorescence “turn-off” process: Experimental and theoretical DFT-D3 study V Hemalatha, V Vijayakumar Journal of Molecular Structure 1311, 138322 , 2024 2024 Citations: 11
MOST CITED SCHOLAR PUBLICATIONS
Synthesis and antimicrobial activities of novel 1, 5-diaryl pyrazoles RV Ragavan, V Vijayakumar, NS Kumari European Journal of Medicinal Chemistry 45 (3), 1173-1180 , 2010 2010 Citations: 226
Flavonoid from Carica papaya inhibits NS2B-NS3 protease and prevents Dengue 2 viral assembly P Senthilvel, P Lavanya, KM Kumar, R Swetha, P Anitha, S Bag, ... Bioinformation 9 (18), 889 , 2013 2013 Citations: 193
Synthesis and antimicrobial activity of new Schiff bases containing coumarin moiety and their spectral characterization VSV Satyanarayana, P Sreevani, A Sivakumar, V Vijayakumar Arkivoc 17, 221-233 , 2008 2008 Citations: 152
Synthesis of some novel bioactive 4-oxy/thio substituted-1H-pyrazol-5 (4H)-ones via efficient cross-Claisen condensation RV Ragavan, V Vijayakumar, NS Kumari European Journal of Medicinal Chemistry 44 (10), 3852-3857 , 2009 2009 Citations: 123
Investigations on Antibacterial Activity of Leaf Extracts of Azadirachta indica A. Juss (Meliaceae): A Traditional Medicinal Plant of India C Rajasekaran, E Meignanam, V Vijayakumar, T Kalaivani, S Ramya, ... Ethnobotanical Leaflets 12, 1213-1217. , 2008 2008 Citations: 92
New bio-sensitive and biologically active single crystal of pyrimidine scaffold ligand and its gold and platinum complexes: DFT, antimicrobial, antioxidant, DNA interaction … M Sankarganesh, JD Raja, K Sakthikumar, RV Solomon, J Rajesh, ... Bioorganic Chemistry 81, 144-156 , 2018 2018 Citations: 63
Eco-friendly synthesis of silver nanoparticles from the whole plant of Cleome viscosa and evaluation of their characterization, antibacterial, antioxidant and antidiabetic … S Yarrappagaari, R Gutha, L Narayanaswamy, L Thopireddy, L Benne, ... Saudi Journal of Biological Sciences 27 (12), 3601-3614 , 2020 2020 Citations: 58
Molecular characterization of bixin—an important industrial product R Siva, FP Doss, K Kundu, VSV Satyanarayana, V Kumar Industrial Crops and products 32 (1), 48-53 , 2010 2010 Citations: 56
Synthesis of 4-Hydroxy-2 (1H)-Quinolone Derived Chalcones, Pyrazolines and Their Antimicrobial, In Silico Antimalarial Evaluations S Sarveswari, V Vijayakumar, R Siva, R Priya Applied biochemistry and biotechnology 175 (1), 43-64 , 2015 2015 Citations: 55
Structural analysis, antimicrobial and cytotoxic studies on new metal (II) complexes containing N2O2 donor Schiff base ligand IB Amali, MP Kesavan, V Vijayakumar, NI Gandhi, J Rajesh, G Rajagopal Journal of Molecular Structure 1183, 342-350 , 2019 2019 Citations: 51
Rationally designed imidazole derivative as colorimetric and fluorometric sensor for selective, qualitative and quantitative cyanide ion detection in real time samples R Bhaskar, V Vijayakumar, V Srinivasadesikan, SL Lee, S Sarveswari Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 234, 118212 , 2020 2020 Citations: 47
Design, synthesis and biological evaluation of novel azaspiro analogs of linezolid as antibacterial and antitubercular agents PK Gadekar, A Roychowdhury, PS Kharkar, VM Khedkar, M Arkile, ... European Journal of Medicinal Chemistry 122, 475-487 , 2016 2016 Citations: 45
In silico analysis reveals the anti-malarial potential of quinolinyl chalcone derivatives M Thillainayagam, L Pandian, KK Murugan, V Vijayaparthasarathi, ... Journal of Biomolecular Structure and Dynamics 33 (5), 961-977 , 2015 2015 Citations: 41
Nickel oxide nanoparticles catalyzed synthesis of poly-substituted quinolines via Friedlander hetero-annulation reaction B Palakshi, P Iniyavan, S Sarveswari, V Vijayakumar Chinese Chemical Letters, 1595-1600 , 2014 2014 Citations: 39
Characterisation of novel pH indicator of natural dye Oldenlandia umbellata L. S Ramamoorthy, G Mudgal, D Rajesh, F Nawaz Khan, V Vijayakumar, ... Natural Product Research 23 (13), 1210-1217 , 2009 2009 Citations: 38
Magnetic iron oxide nanoparticles (MION s) cross‐linked natural polymer‐based hybrid gel beads: controlled nano anti‐TB drug delivery application MP Kesavan, S Ayyanaar, V Vijayakumar, J Dhaveethu Raja, J Annaraj, ... Journal of Biomedical Materials Research Part A 106 (4), 1039-1050 , 2018 2018 Citations: 37
CuO nanoparticles: synthesis and application as an efficient reusable catalyst for the preparation of xanthene substituted 1, 2, 3-triazoles via click chemistry P Iniyavan, GL Balaji, S Sarveswari, V Vijayakumar Tetrahedron Letters 56 (35), 5002-5009 , 2015 2015 Citations: 37
Microwave-assisted clean synthesis of xanthenes and chromenes in [bmim][PF6] and their antioxidant studies P Iniyavan, S Sarveswari, V Vijayakumar Research on Chemical Intermediates, DOI: 10.1007/s11164-014-1821-4. , 2014 2014 Citations: 34
In Vitro Evaluation of Antibacterial Activity of Phytochemical Extracts from Leaves of Aegle marmelos (L.) Corr. (Rutaceae) C Rajasekaran, N Premkumar, T Kalaivani, R Siva, V Vijayakumar, ... Ethnobotanical Leaflets 12, 1124-1128. , 2008 2008 Citations: 33
Novel sulfamide-containing compounds as selective carbonic anhydrase I inhibitors E Berrino, S Bua, M Mori, M Botta, VS Murthy, V Vijayakumar, Y Tamboli, ... Molecules 22 (7), 1049 , 2017 2017 Citations: 32