luchinochessa

@unica.it

Department of Medical Sciences and Public Health, University of Cagliari
Unit Liver, University Hospital of Cagliari

luchinochessa


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https://researchid.co/luchessa
98

Scopus Publications

2661

Scholar Citations

23

Scholar h-index

51

Scholar i10-index

Scopus Publications

  • Risk of Developing Low-Level Viral Rebound Among People With HIV Receiving 2- or 3-Drug Regimens: A Case-Control Study Nested in the ICONA Cohort
    Alessandra Vergori, Adriana Cervo, Ashley Roen, Roberta Gagliardini, Tommaso Clemente, Valentina Mazzotta, Eugenia Quiros-Roldan, Franco Maggiolo, Sergio Lo Caputo, Cristina Mussini, Andrea Antinori, Alessandro Cozzi-Lepri, ICONA Foundation Study, A d'Arminio Monforte, A Antinori, S Antinori, A Castagna, M Cernuschi, L Cosmaro, A Di Biagio, E Dibrino, E Girardi, S Lo Caputo, G C Marchetti, C Mussini, E Quiros-Roldan, L Sarmati, B Suligoi, C Torti, A d’Arminio Monforte, A Antinori, A Castagna, F Ceccherini-Silberstein, A Cingolani, A Cozzi-Lepri, A Di Biagio, R Gagliardini, A Giacomelli, E Girardi, A Gori, S Lo Caputo, G Marchetti, F Maggiolo, C Mussini, M Puoti, C F Perno, A Tavelli, A Antinori, A Bandera, S Bonora, A Calcagno, A Castagna, F Ceccherini-Silberstein, A Cervo, A Cingolani, P Cinque, A Cozzi-Lepri, A d’Arminio Monforte, A De Vito, A Di Biagio, A Fortunato, R Gagliardini, A M Geretti, A Giacomelli, E Girardi, N Gianotti, A Gori, G Guaraldi, S Lanini, G Lapadula, M Lichtner, A Lai, S Lo Caputo, G Madeddu, F Maggiolo, V Malagnino, I Mastrorosa, G Marchetti, A Mondi, V Mazzotta, C Muccini, C Mussini, S Nozza, C F Perno, S Piconi, C Pinnetti, M C Poliseno, M Puoti, E Quiros Roldan, R Rossotti, S Rusconi, M M Santoro, A Saracino, L Sarmati, V Spagnuolo, N Squillace, V Svicher, L Taramasso, C Tincati, C Torti, A Vergori, A Cozzi-Lepri, S De Benedittis, I Fanti, M Giotta, S Lanini, N Lentini, M Muccio, R Pastorino, A Rodano’, A Roen, A Tavelli, S Bazzichetto, M Cernuschi, L Cosmaro, A Perziano, V Calvino, D Russo, M Farinella, N Policek, V L Del Negro, S Carrara, S Graziano, G Prota, H Sadeghi, V Sala, S Truffa, D Vincenti, R Rovito, A Giacometti, A Costantini, V Barocci, A Saracino, C Santoro, E Milano, L Comi, D Valenti, P Viale, A Zupparoli, S Cretella, E M Erne, A Pieri, E Quiros Roldan, E Focà, S Minniti, B Menzaghi, C Abeli, L Chessa, F Pes, C Sagnelli, L Alessio, G Nunnari, B M Celesia, J Vecchiet, K Falasca, A Pan, S Dal Zoppo, D Segala, A Bartoloni, B Borchi, C Costa, A Castellaccio, S Lo Caputo, A Narducci, M Bassetti, E Pontali, S Blanchi, N Bobbio, C Del Borgo, R Marocco, G Mancarella, S Piconi, C Molteni, S Rusconi, G Canavesi, P Colletti, G Pellicanò, Y Russotto, G Marchetti, S Antinori, A Gori, M Puoti, A Castagna, A Bandera, G Bozzi, M V Cossu, V Iannone, R Lolatto, M C Moioli, G Carrozzo, N Capra, M Augello, D Moschese, C Mussini, M Menozzi, P Bonfanti, G Lapadula, I Gentile, V Esposito, R Viglietti, N Coppola, F M Fusco, G Di Filippo, V Rizzo, N Sangiovanni, S Martini, A M Cattelan, B Bragato, A Cascio, C Iaria, M Trizzino, R Gulminetti, G De Socio, E Schiaroli, G Parruti, F Sozio, D Messeri, S I Bonelli, C Lazzaretti, R Corsini, A Antinori, C Torti, G D’Ettorre, L Sarmati, A Latini, A Cingolani, G Micheli, S Lamonica, M Capozzi, M Camici, I Mezzaroma, M Rivano Capparuccia, G Iaiani, C Stingone, L Gianserra, J Paulicelli, M M Plazzi, L Bortolani, M Fusto, G Madeddu, G Moi, M Fabbiani, F Montagnani, A Franco, R Fontana Del Vecchio, C Ucciferri, C Di Giuli, G C Orofino, G Calleri, G Di Perri, S Bonora, D Meloni, C Tascini, M Cotrufo, G Battagin, S Nicolè, G Starnini, S Dell’Isola
    Open Forum Infectious Diseases, 2026
    Background The risk of developing low-level viral rebound (LLVR) after achieving human immunodeficiency virus HIV-1 (HIV) RNA suppression with 2-drug regimens (2DR) compared to 3-drug regimens (3DR) remains uncertain. Methods We conducted a matched 1:3 case-control study nested within the ICONA cohort including persons with HIV (PWH) who achieved virological suppression (≥2 consecutive HIV-RNA ≤50 copies/mL over 6 months) after 11 November 2014 (baseline [BL]). Cases were defined as PWH experiencing a single HIV-RNA of 51–199 copies/mL after BL (index date); controls were defined as those who maintained HIV-RNA ≤50 copies/mL up to the index date and were matched for history of care gaps and number of drugs failed. The cumulative incidence of LLVR after virological suppression was estimated using Kaplan–Meier methods, and conditional logistic regression models were used to evaluate the association between the current antiretroviral therapy regimen (2DR [dolutegravir/lamivudine, dolutegravir/rilpivirine, dolutegravir/doravirine, or cabotegravir/rilpivirine] vs 3DR [dolutegravir, bictegravir, rilpivirine, doravirine, boosted darunavir, or boosted atazanavir–based with a backbone of tenofovir and lamivudine or emtricitabine]) and LLVR risk. In sensitivity analyses cases were defined as PWH experiencing 2 consecutive HIV-RNA of 51–199 copies/mL. Results Among 1033 PWH (261 cases, 772 matched controls), 21% were female, median age was 43 (interquartile range [IQR], 34–51) years, and BL CD4 count was 601 (IQR, 379–826) cells/μL; 2DR use was 25% in cases versus 29% in controls (P = .23). Two years after viral suppression, cumulative LLVR incidence was 2.7% (95% CI, 2.3%–3.1%) when considering single LLVR events and 1.8% (95% CI, 1.4%–2.1%) when limited to 2 consecutive values. After adjusting for confounding, evidence for an association with current regimen was inconclusive (adjusted odds ratio, 0.86 [95% CI, .57–1.29]). Conclusions Despite the wide range of plausibility, we can exclude a risk of LLVR higher than 29% when using 2DR versus 3DR regimens.
  • Did the COVID-19 pandemic shift the landscape of late HIV diagnosis?
    Giulia Micheli, Annalisa Mondi, Ashley Roen, Lucia Taramasso, Ilenia Luchetti, Valentina Mazzotta, Giulia Marchetti, Loredana Sarmati, Andrea Gori, Giuseppe Lapadula, Cristina Mussini, Antonella D'Arminio Monforte Monforte, Enrico Girardi, Alessandro Cozzi-Lepri, Andrea Antinori, A d’Arminio Monforte, A Antinori, S Antinori, A Castagna, R Cauda, G Di Perri, E Girardi, R Iardino, A Lazzarin, GC Marchetti, C Mussini, E Quiros-Roldan, L Sarmati, B Suligoi, F von Schloesser, P Viale, F Ceccherini-Silberstein, A Cingolani, A Cozzi-Lepri, A Di Biagio, A Gori, S Lo Caputo, G Marchetti, F Maggiolo, M Puoti, CF Perno, C Torti, A Bandera, S Bonora, A Calcagno, D Canetti, A Cervo, P Cinque, R Gagliardini, A Giacomelli, N Gianotti, G Guaraldi, S Lanini, G Lapadula, M Lichtner, A Lai, G Madeddu, V Malagnino, A Mondi, V Mazzotta, S Nozza, S Piconi, C Pinnetti, E Quiros Roldan, R Rossotti, S Rusconi, MM Santoro, A Saracino, V Spagnuolo, N Squillace, V Svicher, L Taramasso, A Vergori, S De Benedittis, I Fanti, M Giotta, N Lentini, C Marelli, R Pastorino, A Rodano’, A Tavelli, S Bazzichetto, M Cernuschi, L Cosmaro, A Perziano, V Calvino, D Russo, M Farinella, N Policek, VL Del Negro, M Augello, S Carrara, S Graziano, G Prota, S Truffa, D Vincenti, R Rovito, A Giacometti, A Costantini, V Barocci, C Santoro, E Milano, L Comi, C Suardi, L Badia, S Cretella, EM Erne, A Pieri, E Focà, B Menzaghi, C Abeli, L Chessa, F Pes, P Maggi, L Alessio, G Nunnari, BM Celesia, J Vecchiet, K Falasca, A Pan, S Dal Zoppo, D Segala, F Bartalesi, A Bartoloni, B Borchi, C Costa, S Ferrara, M Bassetti, E Pontali, S Blanchi, N Bobbio, C. Del Borgo, R. Marocco, G. Mancarella, C Molteni, G Canavesi, G Pellicanò, Y Russotto, V Bono, MV Cossu, R Lolatto, MC Moioli, L Pezzati, S Diotallevi, C Tincati, M Menozzi, P Bonfanti, V Sangiovanni, I Gentile, V Esposito, N Coppola, FM Fusco, G Di Filippo, V Rizzo, N Sangiovanni, S Martini, AM Cattelan, D Leoni, A Cascio, M Trizzino, D Francisci, E Schiaroli, G Parruti, F Sozio, D Messeri, SI Bonelli, C Lazzaretti, R Corsini, C Mastroianni, A Latini, I Mastrorosa, S Lamonica, M Capozzi, M Camici, I Mezzaroma, M Rivano Capparuccia, G Iaiani, C Stingone, L Gianserra, J Paulicelli, MM Plazzi, G d’Ettore, M Fusto, I Coledan, A De Vito, M Fabbiani, F Montagnani, A Franco, R Fontana Del Vecchio, D Francisci, C Di Giuli, GC Orofino, G Calleri, G Accardo, C Tascini, A Londero, G Battagin, S Nicolè, G Starnini, S Dell’Isola
    International Journal of Infectious Diseases, 2026
    BACKGROUND: The COVID-19 pandemic profoundly disrupted healthcare services. This study assessed the impact of the pandemic on the incidence, characteristics, and outcomes of late HIV diagnosis (LD) in Italy. METHODS: All people with HIV (PWH) enrolled in Italian Cohort Naïve Antiretrovirals during 2016-2019 (prepandemic) and 2021-2024 (postpandemic), and diagnosed with HIV within 3 months before enrolment, were included. LD was defined as CD4 < 350 cells/mm³ or an AIDS-defining event (ADE) within 3 months of HIV diagnosis; AIDS presentation (AIDS-P) was considered an ADE at diagnosis. Annual incidence, socio-demographic determinants, and survival outcomes were compared between periods using Poisson regression, Cox proportional hazards models, and Fine-Gray competing risk models. RESULTS: Among 5724 newly diagnosed PWH, 56% were enrolled in prepandemic and 44% postpandemic. Overall, 58% presented late and 13% as AIDS-P, with proportions stable across periods. Risk factors for LD-female sex, older age, foreign nationality, heterosexual transmission, lower education, and unemployment-remained consistent, with no significant interaction by time (P = 0.39). During follow-up, 151 deaths occurred. LD and especially AIDS-P were associated with substantially increased all-cause mortality compared with non-LD, particularly within the first-year postdiagnosis. Adjusted hazard ratios were 2.96 for LD and 6.51 for AIDS-P prepandemic, and 8.64 and 17.99 postpandemic. No excess risk was observed for non-AIDS-related mortality. CONCLUSION: The prevalence and determinants of LD and AIDS-P in Italy remained stable before and after the COVID-19 pandemic. However, late presentation continues to carry a heavy mortality burden, underscoring the urgent need to strengthen early testing and prompt linkage to care.
  • Implementing the National Vaccination Plan in people with HIV in Italy: A survey among ICONA centres
    Antonio Russo, Andrea Giacomelli, Andrea De Vito, Maria Mazzitelli, Manuela Ceccarelli, Sara De Benedittis, Alessandro Tavelli, Massimo Cernuschi, Lucia Taramasso, Miriam Lichtner, Valentina Mazzotta, Enrico Girardi, Cristina Mussini, Sergio Lo Caputo, Antonella d'Arminio Monforte, and
    HIV Medicine, 2026
    The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.
  • Proportion of newly diagnosed persons with HIV with HIV-RNA greater than/equal to 500 000 copies/mL in 2018–2023 in Italy: data from the ICONA Foundation Cohort Study
    Antonella d'Arminio Monforte, Nicolò Lentini, Alessandro Tavelli, Stefano Rusconi, Federica Sozio, Alessandra Guida, Emanuela Zappulo, Gabriele Loi, Annalisa Mondi, Roberta Gagliardini, Giulia Marchetti, Francesca Ceccherini-Silbrstein, Valentina Mazzotta, Enrico Girardi, Roberta Pastorino, Andrea Giacomelli, Carlo F. Perno, Board of directors, A d'Arminio Monforte, A. Antinori, S. Antinori, A. Castagna, M. Cernuschi, L. Cosmaro, A. Di Biagio, E. Dibrino, E. Girardi, S. Lo Caputo, G.C. Marchetti, C. Mussini, E. Quiros-Roldan, L. Sarmati, B. Suligoi, C. Torti, Scientific secretariat, A d’Arminio Monforte, A. Antinori, A. Castagna, F. Ceccherini-Silberstein, A. Cingolani, A. Cozzi-Lepri, A. Di Biagio, R. Gagliardini, A. Giacomelli, E. Girardi, A. Gori, S. Lo Caputo, G. Marchetti, F. Maggiolo, C. Mussini, M. Puoti, C.F. Perno, A. Tavelli, Steering committee, A Antinori, A. Bandera, S. Bonora, A. Calcagno, A. Castagna, F. Ceccherini-Silberstein, A. Cervo, A. Cingolani, P. Cinque, A. Cozzi-Lepri, A.d’Arminio Monforte, A. De Vito, A. Di Biagio, A. Fortunato, R. Gagliardini, A.M. Geretti, A. Giacomelli, E. Girardi, N. Gianotti, A. Gori, G. Guaraldi, S. Lanini, G. Lapadula, M. Lichtner, A. Lai, S. Lo Caputo, G. Madeddu, F. Maggiolo, V. Malagnino, I. Mastrorosa, G. Marchetti, A. Mondi, V. Mazzotta, C. Muccini, C. Mussini, S. Nozza, C.F. Perno, S. Piconi, C. Pinnetti, M.C. Poliseno, M. Puoti, E Quiros Roldan, R. Rossotti, S. Rusconi, M.M. Santoro, A. Saracino, L. Sarmati, V. Spagnuolo, N. Squillace, V. Svicher, L. Taramasso, C. Tincati, C. Torti, A. Vergori, Statistical, monitoring team, A. Cozzi-Lepri, S. De Benedittis, I. Fanti, M. Giotta, S. Lanini, N. Lentini, M. Muccio, R. Pastorino, A. Rodano’, A. Roen, A. Tavelli, Community advisory board, S. Bazzichetto, M. Cernuschi, L. Cosmaro, A. Perziano, V. Calvino, D. Russo, M. Farinella, N. Policek, V.L. Del Negro, Biological Bank INMI, San Paolo, S. Carrara, S. Graziano, G. Prota, H. Sadeghi, V. Sala, S. Truffa, D. Vincenti, R. Rovito, Participating physicians, centers, Italy A. Giacometti, A. Costantini, V. Barocci, A. Saracino, C. Santoro, E. Milano, L. Comi, C. Suardi, P. Viale, L. Badia, S. Cretella, E.M. Erne, A. Pieri, E Quiros Roldan, E. Focà, S. Minniti, B. Menzaghi, C. Abeli, L. Chessa, F. Pes, P. Maggi, L. Alessio, G. Nunnari, B.M. Celesia, J. Vecchiet, K. Falasca, A. Pan, S Dal Zoppo, D. Segala, A. Bartoloni, B. Borchi, C. Costa, A. Castellaccio, S. Lo Caputo, A. Narducci, M. Bassetti, E. Pontali, S. Blanchi, N. Bobbio, C. Del Borgo, R. Marocco, G. Mancarella, S. Piconi, C. Molteni, S. Rusconi, G. Canavesi, P. Colletti, G. Pellicanò, Y. Russotto, G. Marchetti, S. Antinori, A. Gori, M. Puoti, A. Castagna, A. Bandera, V. Bono, G. Bozzi, M.V. Cossu, V. Iannone, R. Lolatto, M.C. Moioli, G. Carrozzo, N. Capra, M. Augello, D. Moschese, C. Mussini, M. Menozzi, P. Bonfanti, G. Lapadula, V. Sangiovanni, I. Gentile, V. Esposito, N. Coppola, F.M. Fusco, G. Di Filippo, V. Rizzo, N. Sangiovanni, S. Martini, A.M. Cattelan, D. Leoni, A. Cascio, C. Iaria, M. Trizzino, R. Gulminetti, D. Francisci, E. Schiaroli, G. Parruti, F. Sozio, D. Messeri, S.I. Bonelli, C. Lazzaretti, R. Corsini, A. Antinori, C. Torti, G. D'Ettorre, L. Sarmati, A. Latini, A. Cingolani, G. Micheli, S. Lamonica, M. Capozzi, M. Camici, I. Mezzaroma, M Rivano Capparuccia, G. Iaiani, C. Stingone, L. Gianserra, J. Paulicelli, M.M. Plazzi, L. Bortolani, M. Fusto, I. Coledan, G. Madeddu, G. Moi, M. Fabbiani, F. Montagnani, A. Franco, R Fontana Del Vecchio, D. Francisci, C. Di Giuli, G.C. Orofino, G. Calleri, G. Di Perri, S. Bonora, D. Meloni, C. Tascini, A. Londero, G. Battagin, S. Nicolè, G. Starnini, S. Dell’Isola
    Clinical Microbiology and Infection, 2026
  • Human leukocyte antigen-G in hepatocellular carcinoma driven by chronic viral hepatitis or steatotic liver disease
    Stefano Mocci, Andrea Perra, Roberto Littera, Francesco Pes, Maurizio Melis, Celeste Sanna, Alessia Mascia, Michela Murgia, Caterina Mereu, Michela Lorrai, Irena Duś-Ilnicka, Giorgia Zedda, Sara Lai, Erika Giuressi, Federico Guarino, Gianfranco Serra, Michela Miglianti, Roberta Stradoni, Monica Vacca, Teresa Zolfino, Luchino Chessa, Sabrina Giglio
    Scientific Reports, 2025
    Hepatocellular carcinoma (HCC) is the sixth most common cancer globally and the third leading cause of cancer-related mortality, primarily driven by viral infections (HCV, HBV) and steatotic liver diseases (SLD). Despite advances in treatment, early detection and accurate prognosis remain challenging. The Human leukocyte antigen G (HLA-G) molecule is dysregulated in various conditions, including cancers and viral infections. This study aimed to investigate HLA-G's role in viral-related and SLD-driven HCC. We analyzed a cohort of 116 HCC patients and 140 healthy controls to assess HLA-G genetic variants and soluble levels. Results showed significantly higher levels of soluble HLA-G in HCC patients compared to controls (Pc = 0.003). Moreover, overall survival (OS) was significantly lower in patients with the extended HLA-G*01:01:01/UTR-1 haplotype (Log-rank test, p = 0.002), a trend consistent in both HCV and/or HBV-related HCC (p = 0.025) and SLD-related HCC (p = 0.018). Elevated sHLA-G levels were associated with shorter OS across both subgroups (p = 0.034 (HBV/HCV) and p = 0.010 (SLD), respectively). The findings suggest that elevated levels of soluble HLA-G and specific genetic variants are associated with poor prognosis in HCC patients, highlighting the potential of HLA-G as a prognostic biomarker in both viral-related and steatotic liver disease-related HCC.
  • Effectiveness of first-line lamivudine/dolutegravir antiretroviral therapy in persons with HIV: Real-life data from the ICONA Foundation cohort
    Alessandra Vergori, Alessandro Cozzi-Lepri, Sergio Lo Caputo, Alessandro Tavelli, Valentina Mazzotta, Elisabetta Schiaroli, Giancarlo Orofino, Cristina Mussini, Silvia Nozza, Antonella Cingolani, Andrea Antinori, Antonella d’Arminio Monforte, , A d’Arminio Monforte, A Antinori, S Antinori, A Castagna, R Cauda, G Di Perri, E Girardi, R Iardino, A Lazzarin, G C Marchetti, C Mussini, E Quiros-Roldan, L Sarmati, B Suligoi, F von Schloesser, P Viale, A d’Arminio Monforte, A Antinori, A Castagna, F Ceccherini-Silberstein, A Cingolani, A Cozzi-Lepri, A Di Biagio, E Girardi, A Gori, S Lo Caputo, G Marchetti, F Maggiolo, C Mussini, M Puoti, C F Perno, C Torti, A Antinori, A Bandera, S Bonora, A Calcagno, D Canetti, A Castagna, F Ceccherini-Silberstein, A Cervo, A Cingolani, P Cinque, A Cozzi-Lepri, A d’Arminio Monforte, A Di Biagio, R Gagliardini, A Giacomelli, E Girardi, N Gianotti, A Gori, G Guaraldi, S Lanini, G Lapadula, M Lichtner, A Lai, S Lo Caputo, G Madeddu, F Maggiolo, V Malagnino, G Marchetti, A Mondi, V Mazzotta, C Mussini, S Nozza, C F Perno, S Piconi, C Pinnetti, M Puoti, E Quiros Roldan, R Rossotti, S Rusconi, M M Santoro, A Saracino, L Sarmati, V Spagnuolo, N Squillace, V Svicher, L Taramasso, C Torti, A Vergori, A Cozzi-Lepri, S De Benedittis, I Fanti, N Lentini, M Giotta, R Pastorino, A Rodanò, A Roen, A Tavelli, S Bazzichetto, M Cernuschi, L Cosmaro, A Perziano, V Calvino, D Russo, M Farinella, N Policek, V L Del Negro, M Augello, S Carrara, S Graziano, G Prota, S Truffa, D Vincenti, R Rovito, A Giacometti, A Costantini, V Barocci, A Saracino, C Santoro, E Milano, L Comi, C Suardi, P Viale, L Badia, S Cretella, E M Erne, A Pieri, E Quiros Roldan, E Focà, B Menzaghi, C Abeli, L Chessa, F Pes, P Maggi, L Alessio, G Nunnari, B M Celesia, J Vecchiet, K Falasca, A Pan, S Dal Zoppo, D Segala, F Bartalesi, A Bartoloni, B Borchi, C Costa, S Lo Caputo, A Narducci, M Bassetti, E Pontali, S Blanchi, N Bobbio, C Del Borgo, R Marocco, G Mancarella, S Piconi, C Molteni, S Rusconi, G Canavesi, G Pellicanò, Y Russotto, G Marchetti, S Antinori, A Gori, M Puoti, A Castagna, A Bandera, V Bono, M V Cossu, A Giacomelli, R Lolatto, M C Moioli, L Pezzati, S Diotallevi, C Tincati, C Mussini, M Menozzi, P Bonfanti, G Lapadula, V Sangiovanni, I Gentile, V Esposito, N Coppola, F M Fusco, G Di Filippo, V Rizzo, N Sangiovanni, S Martini, A M Cattelan, D Leoni, A Cascio, M Trizzino, D Francisci, E Schiaroli, G Parruti, F Sozio, D Messeri, S I Bonelli, C Lazzaretti, R Corsini, A Antinori, R Cauda, C Mastroianni, L Sarmati, A Latini, A Cingolani, I Mastrorosa, S Lamonica, M Capozzi, M Camici, I Mezzaroma, M Rivano Capparuccia, G Iaiani, C Stingone, L Gianserra, J Paulicelli, M M Plazzi, G d’Ettore, M Fusto, I Coledan, G Madeddu, A De Vito, M Fabbiani, F Montagnani, A Franco, R Fontana Del Vecchio, D Francisci, C Di Giuli, G C Orofino, G Calleri, G Di Perri, S Bonora, G Accardo, C Tascini, A Londero, G Battagin, S Nicolè, G Starnini, S Dell’Isola
    Journal of Antimicrobial Chemotherapy, 2025
    Objectives This analysis aimed to evaluate the rate of failure of first-line lamivudine/dolutegravir in a real-world setting and assess the effectiveness among people with HIV (PWH) at higher risk of suboptimal response. Methods The study included PWH from the ICONA cohort who started first-line lamivudine/dolutegravir between 2016 and 2024. The primary endpoint was time to treatment failure (TF), defined as virological failure (VF, two consecutive HIV-RNA of &amp;gt;50 copies/mL &amp;gt;6 months after treatment initiation) or discontinuation due to toxicity/lack virological control/non-adherence or death for any cause. Secondary endpoints were time to treatment discontinuation for any reason (TD) and pure VF. Main exposures of interest were baseline CD4 and HIV-RNA, age, sex at birth and nation of birth. Standard survival analysis and Cox regression models were used. Results Among 446 participants, after a median follow-up of 22 months, 4.3% (n = 19) experienced TF, the 3 year cumulative probability was 5.8% (95% CI: 2.9%–8.7%). Baseline CD4 count was associated with a 3-fold higher risk of TF, which decreased after adjustments. Higher viral loads (&amp;gt;100 000 copies/mL), age &amp;gt;50 years and foreign-born status were also associated with an increased risk of TF. No differences in TF according to sex at birth were found. By 3 years the probabilities of TD and VF were 13.4% (95% CI: 9.1%–17.6%) and 2.3% (95% CI: 0.19%–4.4%), respectively. Conclusions In our real-world setting, the TF probability for first-line lamivudine/dolutegravir was below 6% at 3 years, lower than in randomized trials. Our data suggest that, as shown with other regimens, PWH starting lamivudine/dolutegravir with CD4 count of ≤200 cells/mm3, HIV-RNA of &amp;gt;100 000 copies/mL, older age or foreign-born status may be at higher risk of TF, though larger studies are needed to qualify the magnitude of the effect.
  • Diagnosed Patients With Chronic Hepatitis B and Delta Virus in Italy in 2024: An Estimation From a National Real-World Database
    Alessandro Loglio, Ivan Gardini, Massimiliano Conforti, Marco Bartoli, Francesco Silvia, Carmine Coppola, Luchino Chessa, Gianluca Svegliati‐Baroni, Laura Schiadà, Ivan Gentile, Biagio Pinchera, Maurizia Rossana Brunetto, Piero Colombatto, Alessio Aghemo, Stella De Nicola, Pierluigi Toniutto, Edoardo Giovanni Giannini, Antonio Colecchia, Dante Romagnoli, Loredana Sarmati, Francesca Romana Ponziani, Filomena Morisco, Calogero Cammà, Giuseppe Cabibbo, Pietro Lampertico, Elisabetta Degasperi, Pietro Invernizzi, Antonio Ciaccio, Francesco Paolo Russo, Antonio Massimo Ippolito, Grazia Anna Niro, Natalia Terreni, Gerardo Nardone, Alba Rocco, Maria D'Antò, David Sacerdoti, Donatella Ieluzzi, Alessia Ciancio, Adriano Pellicelli, Alessandro Federico, Loredana Simone, Vincenzo Messina, Ernesto Claar, Valerio Rosato, Gianpiero D'Offizi, Paolo Caraceni, Paolo Muratori, Cinzia Giaccherini, Stefano Fagiuoli, Mauro Viganò
    Liver International, 2025
    Background and AimsHepatitis B (HBV) and Hepatitis Delta virus (HDV) infection have undergone significant changes in Italy over the past few decades, but reliable and updated prevalence of chronic hepatitis B (CHB) and Delta (CHD) data are lacking. The aim of the study was to describe the epidemiology of CHB and CHD in Italy in 2024, based on real‐world data.MethodsThe number of patients with a healthcare expenditure exemption for CHB (016.070.32) and CHD (016.070.33) was obtained from 21 Regional Health Authorities. To understand how many CHB or CHD patients did not have these specific exemptions, a survey was conducted in 30 Gastroenterology, Hepatology and Infectious Diseases Units across the country.ResultsHealth Authorities data reported 67 514 and 5216 subjects with an exemption for CHB and for CHD, respectively. However, among 6775 CHB and 504 CHD patients, only 60.3% and 55.7% of them had the specific exemption, respectively. Based on these results, we estimated 111 960 (95% CI: 109 780–114 240) CHB and 9360 (95% CI: 8690–10 150) CHD patients, with a prevalence of 0.22% and 0.019% of the adult overall population. Moreover, anti‐HDV prevalence was 7.7% from this cohort.ConclusionOur study provides a plausible estimate of the current number of adult patients diagnosed with CHB and CHD in Italy and may be considered the basis for decision‐making health policies.
  • Comparison of diagnostic performances of HDV-RNA quantification assays used in clinical practice: Results from a national quality control multicenter study
    Romina Salpini, Lorenzo Piermatteo, Gian Paolo Caviglia, Ada Bertoli, Maurizia Rossana Brunetto, Bianca Bruzzone, Annapaola Callegaro, Cinzia Caudai, Daniela Cavallone, Luchino Chessa, Fernando Coghe, Nicola Coppola, Nunzia Cuomo, Stefano D'Anna, Mariantonietta Di Stefano, Floriana Facchetti, Claudio Farina, Donatella Ferraro, Elisa Franchin, Daniela Francisci, Silvia Galli, Anna Rosa Garbuglia, William Gennari, Valeria Ghisetti, Pietro Lampertico, Sergio Lo Caputo, Nadia Marascio, Stefano Menzo, Valeria Micheli, Grazia Anna Niro, Antonella Olivero, Pierpaolo Paba, Concetta Ilenia Palermo, Orazio Palmieri, Stefania Paolucci, Mariantonietta Pisaturo, Teresa Pollicino, Giuseppina Raffa, Teresa Santantonio, Giulia Torre, Ombretta Turriziani, Sergio Uzzau, Sara Colonia Uceda Renteria, Marialinda Vatteroni, Maurizio Zazzi, Antonio Craxì, Francesca Ceccherini-Silberstein, Valentina Svicher, Marco Arosio, Sabrina Bastianelli, Annamaria Gentile, Federica A.M. Giardina, Anna Gidari, Rosalba Govoni, Gabriele Ibba, Alessandro Loglio, Alessandra Lombardi, Chiara Mascarella, Fabrizio Maggi, Giovanni Matera, Chiara Mazzei, Maria Grazia Milia, Angela Quirino, Adriana Raddi, Rosetta Scioscia, Sara Tagliazucchi, Michele Totaro, Rea Valaperta
    Journal of Clinical Virology, 2025
    Introduction A reliable quantification of hepatitis-D virus (HDV) RNA is of paramount importance for monitoring patients under antiviral therapy. This quality-control study compares the diagnostic performances of quantitative HDV-RNA assays used in clinical-practice. Methods Two HDV-RNA sample panels were quantified in 30 centers by RoboGene (N=9 laboratories), EurobioPlex (N=7), RealStar (N=4), AltoStar (N=1), Bosphore (N=3), Bosphore-on-InGenius (N=1), Dia.Pro (N=2), Nuclear-Laser-Medicine (N=1) and 3 in-house assays. Panel-A and -B comprised 8 serial-dilutions of WHO/HDV standard (range:0.5-5.0log10IU/ml) and 20 clinical samples (range:0.5-6.0log10IU/ml), respectively. The following parameters were determined: sensitivity by 95%LOD (limit of detection), precision by intra- and inter-run CV (coefficient of variation), accuracy by the differences between expected-observed HDV-RNA, linearity by linear-regression analysis. Results 95%LOD varied across assays and centers underlining heterogeneous sensitivities: AltoStar had the lowest 95%LOD (3IU/ml) followed by RealStar (10[minmax: 3-316]IU/ml), Bosphore-on-InGenius (10IU/ml), RoboGene (31[3-316]IU/ml), Nuclear-Laser-Medicine (31IU/ml) and EuroBioplex (100[100-316]IU/ml). Moreover, 6 assays (RoboGene,EurobioPlex,RealStar,AltoStar,Nuclear-Laser-Medicine and Inhouse) showed <0.5log10IU/ml differences between expected and observed HDV-RNA for all dilutions while other assays had >1log10IU/ml underestimations. RealStar, Bosphore-on-InGenius and EurobioPlex had the highest precision (mean intra-run CV<20%). Inter-run CV was higher for all assays, with CVs <25% for RealStar, AltoStar, Nuclear-Laser-Medicine and EurobioPlex. Seven assays (RoboGene/AltoStar/RealStar/EurobioPlex/Nuclear-Laser-Medicine/In-house) showed a good linearity (R2>0.90), but for HDV-RNA<1000IU/ml only Bosphore-on-InGenius, AltoStar, RealStar and Robogene showed a R2>0.85. Conclusions This study underlines heterogeneous sensitivities (inter- and intraassays), that could hamper proper HDV-RNA quantification, particularly at low viralloads. This raises the need to improve the diagnostic performance of most assays for properly identifying virological response to anti-HDV drugs.
  • Cancer incidence in people with HIV in Italy: Comparison of the ICONA COHORT with general population data
    Pierluca Piselli, Alessandro Tavelli, Claudia Cimaglia, Camilla Muccini, Alessandra Bandera, Giulia C. Marchetti, Carlo Torti, Valentina Mazzotta, Luca Pipitò, Alessandro Caioli, Enrico Girardi, Andrea Antinori, Diego Serraino, Antonella d'Arminio Monforte, Antonella Cingolani, and
    International Journal of Cancer, 2025
    The cancer risk of people with HIV (PWH) enrolled in the Italian COhort of Naives to Antiretrovirals (ICONA) with HIV diagnosis occurred between 01/1997 and 12/2023 has been compared to that of the corresponding general population of Italy. Incident cancers were grouped according to their association with viral infections. Standardized incidence ratios (SIRs) were estimated as the ratio between the observed number of cancers among PWH and the expected ones among the general population. Competing risks cumulative incidence curves and Gray's test were used to compare incidence between groups (gender and CD4+ T‐cells values at diagnosis) with death as a competing risk. Overall, 17,298 PWH (79.1% males) contributing to 133,851 person‐years of follow‐up were included; 763 (4.4%) developed &gt; = 1 incident cancers, the most frequent cancers being KS (N = 204), NHL (N = 127) and lung‐trachea‐bronchus (N = 66). PWH were at 1.6‐times higher risk for all cancers compared to the general population (SIR = 1.6, 95% CI: 1.5–1.8), with significantly increased SIR for almost all virus‐related cancers, including KS (SIR = 145), NHL (SIR = 5.8), ICC (SIR = 6.0), anal cancer (SIR = 21.0) and Hodgkin lymphoma (SIR = 10.0). Apart from lung cancer risk (SIR = 1.3), none of the non‐virus‐related cancers turned out to be more frequent among PWH. PWH with CD4 + &lt;200 cells/mm3 at cART initiation showed the highest cancer incidence, 5% after 5 years, versus 3% for CD4+ 200–349 and 2% for CD4+ &gt;350 (p &lt; .001). These findings underscore the need to continue prevention efforts in PWH, including behavioral risk reduction, early cART initiation, screening, and vaccination.
  • Long-term effectiveness, safety, and liver stiffness dynamics of PBC treatment with obeticholic acid in real-world
    Francesca Terracciani, Antonio De Vincentis, Daphne D’Amato, Laura Cristoferi, Alessio Gerussi, Pietro Invernizzi, Miki Scaravaglio, Ester Vanni, Daniela Campion, Anna Morgando, Vincenzo Valiani, Vincenzo Boccaccio, Filomena Morisco, Lorenzo Surace, Ilaria Cavalli, Guido Delle Monache, Federico Salomone, Donatella Ieluzzi, Debora Angrisani, Raffaella Tortora, Biagio Cuffari, Alessandra Moretti, Gerardo Nardone, Stefano Fagiuoli, Mauro Viganò, Giovanni Vettori, Federica Cerini, Giancarlo Gimignani, Alberto Mattalia, Fabrizio Pizzolante, Nicoletta De Matthaeis, Cristina Rigamonti, Giulia Francesca Manfredi, Valentina Boano, Paola Begini, Ana Lleo, Francesca Colapietro, Riccardo Plebani, Domenico Alvaro, Rosanna Venere, Elisabetta Degasperi, Marta Borghi, Pietro Lampertico, Edoardo Giovanni Giannini, Sara Labanca, Raffaella Viganò, Federico D'Amico, Antonino Castellaneta, Francesco Squeo, Luca Cadamuro, Luigi Capodicasa, Marco Marzioni, Valerio Buzzanca, Guido Poggi, Alessandro Mussetto, Raffaele Cozzolongo, Francesco Losito, Gaetano Bertino, Maurizio Russello, Mariarita Cannavò, Paolo Scivetti, Maurizio Pompili, Annalisa Tortora, Anna Grazia Niro, Rosa Cotugno, Pietro Pozzoni, Alessia Riva, Luchino Chessa, Michela Miglianti, Giuseppe Cuccorese, Valeria Pace Palitti, Ludovico Abenavoli, Natalia Terreni, Teresa Zolfino, Olivia Morelli, Carlo Saitta, Silvia Casella, Adriano Pellicelli, Maurizia Brunetto, Barbara Coco, Andrea Galli, Fabio Marra, Armando Curto, Annarosa Floreani, Nora Cazzagon, Paolo Rollo, Emanuela Bonaiuto, Loredana Simone, Luigi Muratori, Floriano Rosina, Marco Distefano, Elisa Capello, Valentina Bellia, Rodolfo Sacco, Giuliano Alagna, Leonardo Baiocchi, Lory Saveria Crocé, Chiara Ricci, Paolo Poisa, Antonio Izzi, Sara Boninsegna, Vincenza Calvaruso, Marco Carbone, Umberto Vespasiani-Gentilucci, Giulia Di Pasquale, Paolo Gallo, Cossiga Valentina, Falbo Elisabetta, Tatonetti Riccardo, Musumeci Martina, Christou Chrysanthi, Paolo Villa, Eugenia Pesatori, Alessandro Loglio, Alessandro Conforti, Valentina Feletti, Alessandra Garriba, Evelise Frazzetto, Sara Alecci, Annalisa Ardiri, Martina Costanzo, Francesca Romana Ponziani, Francesca Fianchi, Niccolò Bina, Francesca Zani, Barbara Omazzi, Olga Falco, Jessica Piroddu, Anna Rocca, Paola Carnì, Giuseppe Grassi, Francesco Pezzato, Erica D'Ovidio, Matteo Peviani, Alessandro Bellia, Maria Cristina Sapere, Massimiliano Loreno, Masutti Flora, Fusaro Lisa, Riccardo Perbellini, Roberta Soffredini, Concetta Pitrone, Roberto Filomia, Alba Rocco, Pasquale De Crescenzo, Pasquale Piscitelli, Francesca Toffolon, Fabiana Marchetti, Alessandro Inno, Marco Guarracino, Giovan Giuseppe Di Costanzo, Nicola Alessi, Maria Cristina Neglia, Scudu Chiara
    Jhep Reports, 2025
    <h2>Abstract</h2><h3>Background and Aims</h3> A number of studies have assessed short-term effectiveness and safety of obeticholic acid (OCA) in the real-world setting. We aimed to extend the knowledge on real-world OCA treatment effectiveness and safety by expanding sample size and follow-up, and by exploring liver stiffness measurement (LSM) changes over time. <h3>Methods</h3> The RECAPITULATE project involves centres belonging to the "Italian-PBC-registry" and/or the "Club-Epatologi-Ospedalieri" (CLEO) PBC working group. Effectiveness was evaluated as biochemical response according to PBC-OCA-International-Study-of-Efficacy (POISE) and normal range (NR) criteria (normal ALP/ALT/bilirubin). Safety was assessed as incidence of <i>de novo</i>/worsening pruritus and discontinuation rate/causes. Available LSMs were also captured. <h3>Results</h3> We included 747 patients from 66 Italian centres [58 years; F/M 88%/14%, median follow-up 24 months (IQR 12-42), 28% with cirrhosis, and 14% with autoimmune hepatitis (AIH)/PBC overlap]. Probabilities of POISE and NR response increased from baseline up to 57% and 20% at the 42nd month, respectively. They were lower in cirrhosis (<i>p</i>=0.02 and <i>p</i>=0.004 for POISE and NR), while not different between AIH/PBC overlap and PBC (<i>p</i>=0.8). Overall, 130 patients (17%) discontinued treatment, mainly due to pruritus (36.9%), while 28.5% did so after developing hepatic events. Discontinuation rate was higher in cirrhosis (<i>p</i><0.001). LSM was available in 573 patients (∼77%), of whom 255 had multiple measurements. LSM variation over time differed based on the attainment of POISE biochemical response ([expected mean annual variation -0.48 (-0.78, -0.19)] in responders, +0.33 (-0.07, 0.73) in non-responders, respectively, p<0.001]). <h3>Conclusions</h3> These findings from a comprehensive real-world cohort of PBC patients treated with OCA confirm the drug's effectiveness and safety profiles in the medium/long term and demonstrate that biochemical response impacts the trend of LSM over time. <h3>Impact and Implications</h3> After the conditional approval of OCA for the treatment of PBC, the main confirmatory study failed to demonstrate OCA's ability to reduce liver-related events, leading EMA to revoke the drug's marketing authorization. The ensuing scientific debate highlights an urgent need for further evidence from real-world practice. In the largest real-world series of patients treated with OCA to date, we confirm that the drug's effectiveness and safety profiles are maintained over a medium-to-long follow-up period. Valuable data for the management of the drug in relevant subgroups of patients, such as those with cirrhosis and autoimmune hepatitis/PBC overlap, are also provided. Our original results on liver stiffness measurement trend over time suggest a favourable impact of OCA on fibrosis progression, particularly in patients achieving a biochemical response to the drug. Overall, these data provide important insights for clinicians managing patients with PBC, and are also highly valuable for the ongoing scientific debate about the effectiveness/safety profile of this drug.
  • Brief Report: New HIV Diagnoses in PrEP-Experienced and PrEP-Naive Persons in the ICONA Cohort
    Lucia Taramasso, Roberto Rossotti, Alessandro Tavelli, Maria M. Santoro, Valentina Mazzotta, Alessandra Bandera, Gabriella D'Ettorre, Eugenio Milano, Giovanni Francesco Pellicano, Chiara Baiguera, Elena Bruzzesi, Antonella D'Arminio Monforte, Andrea Antinori, Silvia Nozza, and
    Journal of Acquired Immune Deficiency Syndromes 1999, 2025
  • Impact of the Human Leukocyte Antigen Complex on Idiopathic Pulmonary Fibrosis Development and Progression in the Sardinian Population
    Marina Serra, Stefano Mocci, Silvia Deidda, Maurizio Melis, Luchino Chessa, Sara Lai, Erika Giuressi, Caterina Mereu, Celeste Sanna, Michela Lorrai, Michela Murgia, Federica Cannas, Alessia Mascia, Andrea Perra, Roberto Littera, Sabrina Giglio
    International Journal of Molecular Sciences, 2025
  • The role of HLA-G in primary biliary cholangitis and response to therapy
    Michela Miglianti, Stefano Mocci, Roberto Littera, Giancarlo Serra, Cinzia Balestieri, Maria Conti, Francesco Pes, Silvia Deidda, Michela Lorrai, Caterina Mereu, Michela Murgia, Celeste Sanna, Alessia Mascia, Francesca Sedda, Irena Duś-Ilnicka, Selene Cipri, Mauro Giovanni Carta, Sara Lai, Erika Giuressi, Maurizio Melis, Teresa Zolfino, Sabrina Giglio, Andrea Perra, Luchino Chessa
    Frontiers in Immunology, 2025
  • Humoral responses to wild type and ancient BA.1 SARS-CoV-2 variant after heterologous priming vaccination with ChAdOx1 nCoV-19 and BNT162b2 booster dose
    Giuseppina Sanna, Alessandra Marongiu, Davide Firinu, Cristina Piras, Vanessa Palmas, Massimiliano Galdiero, Luigi Atzori, Paola Caria, Marcello Campagna, Andrea Perra, Giulia Costanzo, Ferdinando Coghe, Roberto Littera, Luchino Chessa, Aldo Manzin
    Clinical and Experimental Medicine, 2024
  • Development and Validation of a Scoring System to Predict Response to Obeticholic Acid in Primary Biliary Cholangitis
    Antonio De Vincentis, Javier Ampuero, Francesca Terracciani, Daphne D’Amato, Alessio Gerussi, Laura Cristoferi, Nora Cazzagon, Emanuela Bonaiuto, Annarosa Floreani, Vincenza Calvaruso, Luca Cadamuro, Elisabetta Degasperi, Anna Morgando, Ester Vanni, Ana Lleo, Francesca Colapietro, Domenico Alvaro, Antonino Castellaneta, Sara Labanca, Mauro Viganò, Marco Distefano, Valeria Pace Palitti, Chiara Ricci, Nicoletta De Matthaeis, Marco Marzioni, Elena Gómez-Dominguez, Jose-Luis Montero, Esther Molina, Luisa Garcia-Buey, Marta Casado, Marina Berenguer, Isabel Conde, Miguel-Angel Simon, Javier Fuentes, Pedro Costa-Moreira, Guilherme Macedo, Francisco Jorquera, Rosa-Maria Morillas, Jose Presa, Jose-Manuel Sousa, Dario Gomes, Luis Santos, Antonio Olveira, Manuel Hernandez-Guerra, Leire Aburruza, Arsenio Santos, Armando Carvalho, Juan Uriz, Maria-Luisa Gutierrez, Elia Perez, Luchino Chessa, Adriano Pellicelli, Massimo Marignani, Luigi Muratori, Grazia Anna Niro, Maurizia Brunetto, Francesca Romana Ponziani, Maurizio Pompili, Fabio Marra, Andrea Galli, Alessandro Mussetto, Giuliano Alagna, Loredana Simone, Gaetano Bertino, Floriano Rosina, Raffaele Cozzolongo, Maurizio Russello, Leonardo Baiocchi, Carlo Saitta, Natalia Terreni, Teresa Zolfino, Cristina Rigamonti, Raffaella Vigano, Giuseppe Cuccorese, Pietro Pozzoni, Claudio Pedone, Simone Grasso, Antonio Picardi, Pietro Invernizzi, Rodolfo Sacco, Antonio Izzi, Conrado Fernandez-Rodriguez, Umberto Vespasiani-Gentilucci, Marco Carbone, Miki Scaravaglio, Eugenia Nofit, Paolo Gallo, Giovanni Galati, Francesco Pezzato, Paolo Rollo, Erica D’Ovidio, Barbara Coco, Annalisa Tortora, Cecilia Fiorini, Rosanna Venere, Gaetano Scifo, Mariarita Cannavò, Valentina Feletti, Fabrizio Pizzolante, Edoardo Giovanni Giannini, Rosa Cotugno, Silvia Fanella, Francesco Losito, Giuseppe Grassi, Giulia Francesca Manfredi, Valerio Buzzanca, Barbara Omazzi, Silvia Casella, Francesca Zani, Chiara Ricci, Valentina Bellia, Ludovico Abenavoli, Olivia Morelli, Lory Saveria Crocè, Paolo Scivetti, Antonio Panero, Valentina Boano, Guido Poggi, Giancarlo Gimignani, Alessandro Conforti, Evelise Frazzetto, Laura Rapisarda, Shrin Demma
    Clinical Gastroenterology and Hepatology, 2024
  • A holistic evaluation of patients with chronic Hepatitis D virus (HDV) infection enrolled in the Italian PITER-B and delta cohort
    Loreta A. Kondili, Giuseppina Brancaccio, Maria Elena Tosti, Barbara Coco, Maria Giovanna Quaranta, Vincenzo Messina, Alessia Ciancio, Filomena Morisco, Valentina Cossiga, Ernesto Claar, Valerio Rosato, Marianna Ciarallo, Irene Cacciola, Francesca Romana Ponziani, Lucia Cerrito, Roberta Coppola, Francesco Longobardi, Elisa Biliotti, Alessia Rianda, Francesco Barbaro, Nicola Coppola, Maria Stanzione, Francesco Barchiesi, Stefano Fagiuoli, Mauro Viganò, Marco Massari, Francesco Paolo Russo, Alberto Ferrarese, Diletta Laccabue, Vito Di Marco, Pierluigi Blanc, Aldo Marrone, Giulia Morsica, Alessandro Federico, Donatella Ieluzzi, Alba Rocco, Francesco Giuseppe Foschi, Alessandro Soria, Ivana Maida, Luchino Chessa, Michele Milella, Elena Rosselli Del Turco, Salvatore Madonia, Liliana Chemello, Ivan Gentile, Pierluigi Toniutto, Matteo Bassetti, Lorenzo Surace, Leonardo Baiocchi, Adriano Pellicelli, Adriano De Santis, Massimo Puoti, Elisabetta Degasperi, Grazia Anna Niro, Anna Linda Zignego, Antonio Craxi, Giovanni Raimondo, Teresa Antonia Santantonio, Maurizia Rossana Brunetto, Giovanni Battista Gaeta, Alessio Aghemo, Chiara Baiguera, Pier Maria Battezzati, Sara Battistella, Maria Grazia Bavetta, Costanza Bertoni, Carolina Boni, Paola Brambilla, Antonella Bray, Federica Briano, Enrico Carmenini, Francesco Castelli, Luisa Cavalletto, Federica Cerini, Luciana Chidichimo, Elisa Colella, Giuliana Cologni, Silvia Como, Romina Corsini, Chiara Costa, Rosa Cotugno, Silvia Cretella, Fernando De Angelis, Pasqualina De Leo, Giovanni Di Perri, Elisabetta Falbo, Luigina Ferrigno, Ezio Fornasiere, Daniela Francisci, Pietro Gatti, Pietro Lampertico, Ilaria Lenci, Anna Licata, Ivana Maida, Alfredo Marzano, Antonio Mastroianni, Cesare Mazzaro, Monica Monti, Gerardo Nardone, Laura Ambra Nicolini, Nicola Passigato, Maria Bruna Pasticci, Piera Pierotti, Biagio Pinchera, Teresa Pollicino, Carmen Porcu, Giulia Quartini, Gabriele Rancatore, Mario Romeo, Maria Grazia Rumi, Annalisa Saracino, Ornella Schioppa, Ilaria Serio, Roberta Soffredini, Xhimi Tata, Marco Tizzani, Matteo Tonnini, Carlo Torti, Daniela Valenti, Serena Zaltron, Alessia Zoncada
    International Journal of Infectious Diseases, 2024
  • Prevalence of Apical Periodontitis in Patients with Autoimmune Liver Diseases on Immune Suppressants and Immune Modulators: A Cross-sectional Study
    Francesca Ideo, Sadia Niazi, Luchino Chessa, Michela Miglianti, Giulia Bardini, Francesco Mannocci, Elisabetta Cotti
    Journal of Endodontics, 2024
  • The Effect of Exposure to SARS-CoV-2 Vaccination and Infection on Humoral and Cellular Immunity in a Cohort of Patients with Immune-Mediated Diseases: A Pilot Study
    Giulia Anna Maria Luigia Costanzo, Giuseppina Sanna, Francesco Pes, Carla Maria Deiana, Andrea Giovanni Ledda, Andrea Perra, Vanessa Palmas, Valeria Manca, Michela Miglianti, Ferdinando Coghe, Aldo Manzin, Stefano Del Giacco, Luchino Chessa, Davide Firinu
    Pathogens, 2024
  • The Stability of Social and Behavioral Rhythms and Unexpected Low Rate of Relevant Depressive Symptoms in Old Adults during the COVID-19 Pandemic
    Federica Sancassiani, Giulia Cossu, Elisa Cantone, Ferdinando Romano, Alessandra Perra, Antonio Urban, Samantha Pinna, Stefano Del Giacco, Roberto Littera, Davide Firinu, Luchino Chessa, Enzo Tramontano, Antonio Egidio Nardi, Mauro Giovanni Carta
    Journal of Clinical Medicine, 2024
  • Further decompensation in cirrhosis: Results of a large multicenter cohort study supporting Baveno VII statements
    Gennaro D’Amico, Alexander Zipprich, Càndid Villanueva, Juan Antonio Sordà, Rosa Maria Morillas, Matteo Garcovich, Montserrat García Retortillo, Javier Martinez, Paul Calès, Mario D’Amico, Matthias Dollinger, Marta García-Guix, Esteban Gonzalez Ballerga, Emmanuel Tsochatzis, Isabel Cirera, Agustìn Albillos, Guillaume Roquin, Linda Pasta, Alan Colomo, Jorge Daruich, Nuria Canete, Jérôme Boursier, Marcello Dallio, Antonio Gasbarrini, Angelo Iacobellis, Giulia Gobbo, Manuela Merli, Alessandro Federico, Gianluca Svegliati Baroni, Pietro Pozzoni, Luigi Addario, Luchino Chessa, Lorenzo Ridola, Guadalupe Garcia-Tsao
    Hepatology, 2024
  • Predicting de-novo portal vein thrombosis after HCV eradication: A long-term competing risk analysis in the ongoing PITER cohort
    Loreta A. Kondili, Alberto Zanetto, Maria Giovanna Quaranta, Luigina Ferrigno, Valentina Panetta, Vincenza Calvaruso, Anna Linda Zignego, Maurizia R. Brunetto, Giovanni Raimondo, Elisa Biliotti, Donatella Ieluzzi, Andrea Iannone, Salvatore Madonia, Liliana Chemello, Luisa Cavalletto, Carmine Coppola, Filomena Morisco, Francesco Barbaro, Anna Licata, Alessandro Federico, Federica Cerini, Marcello Persico, Maurizio Pompili, Alessia Ciancio, Fabio Piscaglia, Luchino Chessa, Andrea Giacometti, Pietro Invernizzi, Giuseppina Brancaccio, Antonio Benedetti, Leonardo Baiocchi, Ivan Gentile, Nicola Coppola, Gerardo Nardone, Antonio Craxì, Francesco Paolo Russo, and
    United European Gastroenterology Journal, 2024
  • Impact of Exposure to Vaccination and Infection on Cellular and Antibody Response to SARS-CoV-2 in CVID Patients Through COVID-19 Pandemic
    Giulia Anna Maria Luigia Costanzo, Carla Maria Deiana, Giuseppina Sanna, Andrea Perra, Marcello Campagna, Andrea Giovanni Ledda, Ferdinando Coghe, Vanessa Palmas, Riccardo Cappai, Aldo Manzin, Luchino Chessa, Stefano Del Giacco, Davide Firinu
    Journal of Clinical Immunology, 2024
  • Virtual reality cognitive remediation tool for individuals with mild cognitive impairment: study protocol for a feasibility randomized clinical trial
    Alessandra Perra, Diego Primavera, Valerio Leonetti, Roberta Montisci, Daniele Carta, Giulia Lorrai, Aurora Locci, Luchino Chessa, Angelo Scuteri, Giulia Cossu, Antonio Egidio Nardi, Lucia Valmaggia, Alessia Galetti, Valerio De Lorenzo, Federica Sancassiani, Mauro Giovanni Carta
    Frontiers in Public Health, 2024
  • MICA and NKG2D gene polymorphisms influence graft survival, and response to therapy in kidney transplantation
    Roberto Littera, Stefano Mocci, Davide Argiolas, Letizia Littarru, Sara Lai, Maurizio Melis, Celeste Sanna, Caterina Mereu, Michela Lorrai, Alessia Mascia, Andrea Angioi, Giacomo Mascia, Valeria Matta, Nicola Lepori, Matteo Floris, Cristina Manieli, Paola Bianco, Daniela Onnis, Stefania Rassu, Silvia Deidda, Mauro Giovanni Carta, Erika Giuressi, Andrea Perra, Luchino Chessa, Sabrina Giglio, Antonello Pani
    Frontiers in Immunology, 2024
  • Combined Salivary Proteome Profiling and Machine Learning Analysis Provides Insight into Molecular Signature for Autoimmune Liver Diseases Classification
    Giulia Guadalupi, Cristina Contini, Federica Iavarone, Massimo Castagnola, Irene Messana, Gavino Faa, Simona Onali, Luchino Chessa, Rui Vitorino, Francisco Amado, Giacomo Diaz, Barbara Manconi, Tiziana Cabras, Alessandra Olianas
    International Journal of Molecular Sciences, 2023
  • Profiling the risk of hepatocellular carcinoma after long-term HCV eradication in patients with liver cirrhosis in the PITER cohort
    Loreta A. Kondili, Maria Giovanna Quaranta, Luisa Cavalletto, Vincenza Calvaruso, Luigina Ferrigno, Roberta D'Ambrosio, Ilaria Simonelli, Giuseppina Brancaccio, Giovanni Raimondo, Maurizia R. Brunetto, Anna Linda Zignego, Carmine Coppola, Andrea Iannone, Elisa Biliotti, Gabriella Verucchi, Marco Massari, Anna Licata, Francesco Barbaro, Marcello Persico, Francesco Paolo Russo, Filomena Morisco, Maurizio Pompili, Mauro Viganò, Massimo Puoti, Teresa Santantonio, Erica Villa, Antonio Craxì, Liliana Chemello, Valentina Panetta, Giovanni Battista Gaeta, Roberto Filomia, Barbara Coco, Monica Monti, Daniela Caterina Amoruso, Salvatore Madonia, Donatella Ieluzzi, Gloria Taliani, Lorenzo Badia, Guglielmo Marco Migliorino, Alessia Giorgini, Mario Masarone, Pierluigi Blanc, Valentina Cossiga, Martina De Siena, Xhimi Tata, Maria Grazia Rumi, Luchino Chessa, Pietro Lampertico, Carlo Ferrari, Ivan Gentile, Giustino Parruti, Leonardo Baiocchi, Alessia Ciancio, Pietro Invernizzi, Alessandro Federico, Carlo Torti, Giulia Morsica, Pietro Andreone, Alessio Aghemo, Patrizia Popoli, Stefano Vella
    Digestive and Liver Disease, 2023
  • Trends in chronic hepatitis B virus infection in Italy over a 10-year period: Clues from the nationwide PITER and MASTER cohorts toward elimination
    Giuseppina Brancaccio, Barbara Coco, Alessandra Nardi, Maria Giovanna Quaranta, Maria Elena Tosti, Luigina Ferrigno, Irene Cacciola, Vincenzo Messina, Luchino Chessa, Filomena Morisco, Michele Milella, Francesco Barbaro, Alessia Ciancio, Francesco Paolo Russo, Nicola Coppola, Pierluigi Blanc, Ernesto Claar, Gabriella Verucchi, Massimo Puoti, Anna Linda Zignego, Liliana Chemello, Salvatore Madonia, Stefano Fagiuoli, Alfredo Marzano, Carlo Ferrari, Pietro Lampertico, Vito Di Marco, Antonio Craxì, Teresa Antonia Santantonio, Giovanni Raimondo, Maurizia R. Brunetto, Giovanni Battista Gaeta, Loreta A. Kondili, Luisa Pasulo, Carmine Coppola, Federica Pisano, Mariarosaria Romano, Carmen Porcu, Irene Francesca Bottalico, Valentina Cossiga, Xhimi Tata, Caterina Sagnelli, Piera Pierotti, Elisabetta Degasperi, Valerio Rosato, Lorenzo Badia, Dontella Ieluzzi, Monica Monti, Maria Grazia Bavetta, Luisa Cavalletto, Pierluigi Toniutto, Ezio Fornasiere, Antonio Colecchia, Alberto Ferrarese, Gerardo Nardone, Alba Rocco, Mauro Viganò, Francesco Giuseppe Foschi, Fabio Conti, Giulia Morsica, Stefania Salpietro, Carlo Torti, Chiara Costa, Alessandro Federico, Marcello Dallio, Alessia Giorgini, Marco Anselmo, Pasqualina De Leo, Serena Zaltron, Anna Cambianica, Fabio Piscaglia, Ilaria Serio, Simona Schivazappa, Antonio Mastroianni, Luciana Chidichimo, Marco Massari, Cesare Mazzaro, Aldo Marrone, Francesca Maria D'Amore, Gianpiero D'Offizi, Anna Licata, Grazia Anna Niro, Teresa Pollicino, Alessio Aghemo
    International Journal of Infectious Diseases, 2023
  • COVID-19 Vaccine Hesitancy among Italian Healthcare Workers: Latent Profiles and Their Relationships to Predictors and Outcome
    Igor Portoghese, Melinda Siddi, Luchino Chessa, Giulia Costanzo, Vanessa Garcia-Larsen, Andrea Perra, Roberto Littera, Giada Sambugaro, Stefano Del Giacco, Marcello Campagna, Davide Firinu
    Vaccines, 2023
  • Direct-acting antivirals used in HCV-related liver disease do not affect thyroid function and autoimmunity
    R. Rodia, P. E. Meloni, C. Mascia, C. Balestrieri, V. Ruggiero, G. Serra, M. Conti, M. Loi, F. Pes, S. Onali, A. Perra, R. Littera, F. Velluzzi, S. Mariotti, L. Chessa, F. Boi
    Journal of Endocrinological Investigation, 2023
  • Decision trees for early prediction of inadequate immune response to coronavirus infections: a pilot study on COVID-19
    Fabio Pisano, Barbara Cannas, Alessandra Fanni, Manuela Pasella, Beatrice Canetto, Sabrina Rita Giglio, Stefano Mocci, Luchino Chessa, Andrea Perra, Roberto Littera
    Frontiers in Medicine, 2023
  • Comparing the responses of countries and National Health Systems to the COVID-19 pandemic: a critical analysis with a case-report series
    M. G. Carta, G. Orrù, R. Littera, D. Firinu, L. Chessa, G. Cossu, D. Primavera, S. Del Giacco, E. Tramontano, N. Manocchio, C. Buonomo, A. Scano
    European Review for Medical and Pharmacological Sciences, 2023
  • Top-Down Proteomics Detection of Potential Salivary Biomarkers for Autoimmune Liver Diseases Classification
    Alessandra Olianas, Giulia Guadalupi, Tiziana Cabras, Cristina Contini, Simone Serrao, Federica Iavarone, Massimo Castagnola, Irene Messana, Simona Onali, Luchino Chessa, Giacomo Diaz, Barbara Manconi
    International Journal of Molecular Sciences, 2023
  • A review of the main genetic factors influencing the course of COVID-19 in Sardinia: the role of human leukocyte antigen-G
    Stefano Mocci, Roberto Littera, Luchino Chessa, Marcello Campagna, Maurizio Melis, Carla Maria Ottelio, Ignazio S. Piras, Sara Lai, Davide Firinu, Stefania Tranquilli, Alessia Mascia, Monica Vacca, Daniele Schirru, Luigi Isaia Lecca, Stefania Rassu, Federica Cannas, Celeste Sanna, Mauro Giovanni Carta, Francesca Sedda, Erika Giuressi, Selene Cipri, Michela Miglianti, Andrea Perra, Sabrina Giglio
    Frontiers in Immunology, 2023
  • What do young people know about HIV? Results of a cross sectional study on 18-24-year-old students
    A. Mereu, A. Liori, Luca Fadda, Massimiliano Puddu, L. Chessa, P. Contu, C. Sardu
    Journal of Preventive Medicine and Hygiene, 2022
  • Predictors of serious adverse events and non-response in cirrhotic patients with primary biliary cholangitis treated with obeticholic acid
    Antonio De Vincentis, Daphne D'Amato, Laura Cristoferi, Alessio Gerussi, Federica Malinverno, Ana Lleo, Francesca Colapietro, Fabio Marra, Andrea Galli, Cecilia Fiorini, Barbara Coco, Maurizia Brunetto, Grazia Anna Niro, Rosa Cotugno, Carlo Saitta, Raffaele Cozzolongo, Francesco Losito, Edoardo Giovanni Giannini, Sara Labanca, Marco Marzioni, Giulia Marconi, Anna Morgando, Rinaldo Pellicano, Ester Vanni, Nora Cazzagon, Annarosa Floreani, Luchino Chessa, Olivia Morelli, Luigi Muratori, Adriano Pellicelli, Maurizio Pompili, Francesca Ponziani, Annalisa Tortora, Floriano Rosina, Maurizio Russello, Mariarita Cannavò, Loredana Simone, Silvia Storato, Mauro Viganò, Ludovico Abenavoli, Maria D'Antò, Elisabetta De Gasperi, Marco Distefano, Gaetano Scifo, Teresa Zolfino, Vincenza Calvaruso, Giuseppe Cuccorese, Valeria Pace Palitti, Rodolfo Sacco, Gaetano Bertino, Evelise Frazzetto, Domenico Alvaro, Giacomo Mulinacci, Andrea Palermo, Miki Scaravaglio, Francesca Terracciani, Giovanni Galati, Vincenzo Ronca, Massimo Zuin, Ernesto Claar, Antonio Izzi, Antonio Picardi, Pietro Invernizzi, Umberto Vespasiani‐Gentilucci, Marco Carbone, Valentina Feletti, Alessandro Mussetto, Rosanna Venere, Giulia Bernaccioni, Marie Graciella Pigozzi, Stefano Fagiuoli, Natalia Terreni, Pietro Pozzoni, Leonardo Baiocchi, Giuseppe Grassi, Maria Vinci, Valentina Bellia, Roberto Boldizzoni, Silvia Casella, Barbara Omazzi, Guido Poggi, and
    Liver International, 2022
  • The double-sided of human leukocyte antigen-G molecules in type 1 autoimmune hepatitis
    Roberto Littera, Andrea Perra, Michela Miglianti, Ignazio S. Piras, Stefano Mocci, Sara Lai, Maurizio Melis, Teresa Zolfino, Cinzia Balestrieri, Maria Conti, Giancarlo Serra, Francesco Figorilli, Davide Firinu, Simona Onali, Laura Matta, Carmen Porcu, Francesco Pes, Daniela Fanni, Cristina Manieli, Monica Vacca, Roberto Cusano, Marcello Trucas, Selene Cipri, Stefania Tranquilli, Stefania Rassu, Federica Cannas, Mauro Giovanni Carta, Marta Anna Kowalik, Erika Giuressi, Gavino Faa, Luchino Chessa, Sabrina Giglio
    Frontiers in Immunology, 2022
  • Evaluation of antibody response to BNT162b2 mRNA COVID-19 vaccine in patients affected by immune-mediated inflammatory diseases up to 5 months after vaccination
    Davide Firinu, Andrea Perra, Marcello Campagna, Roberto Littera, Giuseppe Fenu, Federico Meloni, Selene Cipri, Francesca Sedda, Maria Conti, Michela Miglianti, Giulia Costanzo, Marta Secci, Gianmario Usai, Mauro Giovanni Carta, Riccardo Cappai, Germano Orrù, Stefano Del Giacco, Ferdinando Coghe, Luchino Chessa
    Clinical and Experimental Medicine, 2022
  • Evaluation of humoral and cellular response to third dose of BNT162b2 mRNA COVID-19 vaccine in patients treated with B-cell depleting therapy
    Davide Firinu, Giuseppe Fenu, Giuseppina Sanna, Giulia A. Costanzo, Andrea Perra, Marcello Campagna, Roberto Littera, Carlotta Locci, Alessandra Marongiu, Riccardo Cappai, Maurizio Melis, Germano Orrù, Stefano Del Giacco, Ferdinando Coghe, Aldo Manzin, Luchino Chessa
    Journal of Autoimmunity, 2022
  • Differences in lethality and diffusion of Covid-19 in countries using different kinds of vaccines
    Mauro Giovanni Carta, Germano Orrù, Ambra Peracchia, Giulia Cossu, Fernanda Velluzzi, Laura Atzori, Caterina Ferreli, Cesar Ivan Aviles Gonzalez, Ferdinando Romano, Roberto Littera, Roberto Puxeddu, Luchino Chessa, Davide Firinu, Stefano Del Giacco, Angelo Restivo, Simona Deidda, Alessandra Scano, Ferdinando Coghe, Luigi Minerba, Maria Manconi, Luca Saba
    Journal of Public Health Research, 2022
  • A prospective study of direct-acting antiviral effectiveness and relapse risk in HCV cryoglobulinemic vasculitis by the Italian PITER cohort
    Loreta A. Kondili, Monica Monti, Maria Giovanna Quaranta, Laura Gragnani, Valentina Panetta, Giuseppina Brancaccio, Cesare Mazzaro, Marcello Persico, Mario Masarone, Ivan Gentile, Pietro Andreone, Salvatore Madonia, Elisa Biliotti, Roberto Filomia, Massimo Puoti, Anna Ludovica Fracanzani, Diletta Laccabue, Donatella Ieluzzi, Carmine Coppola, Maria Grazia Rumi, Antonio Benedetti, Gabriella Verucchi, Barbara Coco, Liliana Chemello, Andrea Iannone, Alessia Ciancio, Francesco Paolo Russo, Francesco Barbaro, Filomena Morisco, Luchino Chessa, Marco Massari, Pierluigi Blanc, Anna Linda Zignego
    Hepatology, 2022
  • A Protective HLA Extended Haplotype Outweighs the Major COVID-19 Risk Factor Inherited From Neanderthals in the Sardinian Population
    Stefano Mocci, Roberto Littera, Stefania Tranquilli, Aldesia Provenzano, Alessia Mascia, Federica Cannas, Sara Lai, Erika Giuressi, Luchino Chessa, Goffredo Angioni, Marcello Campagna, Davide Firinu, Maria Del Zompo, Giorgio La Nasa, Andrea Perra, Sabrina Giglio
    Frontiers in Immunology, 2022
  • Neutralizing Antibodies Responses against SARS-CoV-2 in a Sardinian Cohort Group Up to 9 Months after BNT162b2 Vaccination
    Giuseppina Sanna, Alessandra Marongiu, Davide Firinu, Cristina Piras, Gianluigi Franci, Massimiliano Galdiero, Giuseppe Pala, Vanessa Palmas, Fabrizio Angius, Roberto Littera, Andrea Perra, Germano Orrù, Marcello Campagna, Giulia Costanzo, Federico Meloni, Ferdinando Coghe, Luchino Chessa, Aldo Manzin
    Vaccines, 2022
  • Covid-19 vaccines work but other factors play a relevant role: A data analysis on spread and mortality in 24 countries
    Mauro Giovanni Carta, Germano Orrù, Giulia Cossu, Fernanda Velluzzi, Laura Atzori, Cesar Ivan Aviles Gonzalez, Ferdinando Romano, Roberto Littera, Luchino Chessa, Davide Firinu, Stefano Del Giacco, Angelo Restivo, Simona Deidda, Alessandra Scano, Simona Onali, Goce Kalcev, Ferinando Coghe, Luigi Minerba
    Journal of Public Health Research, 2022
  • Previous functional social and behavioral rhythms affect resilience to COVID-19-related stress among old adults
    Mauro Giovanni Carta, Michele Fornaro, Luigi Minerba, Massimiliano Pau, Fernanda Velluzzi, Laura Atzori, Cesar Ivan Aviles Gonzalez, Ferdinando Romano, Roberto Littera, Luchino Chessa, Davide Firinu, Stefano Del Giacco, Angelo Restivo, Simona Deidda, Germano Orrù, Alessandra Scano, Simona Onali, Ferdinando Coghe, Goce Kalcev, Giulia Cossu
    Journal of Public Health Research, 2022
  • Verifying the Theory of Climate Affecting Lethality of COVID-19 by an Analysis in Two Climatic Zones of Chile
    Cesar Ivan Aviles-Gonzalez, Alessandra Scano, Giulia Cossu, Roberto Littera, Marcello Campagna, Simona Deidda, Ferdinando Romano, Goce Kalcev, Davide Firinu, Federico Meloni, Mauro Giovanni Carta, Stefano Del Giacco, Angelo Restivo, Luigi Zorcolo, Luigi Marongiu, Giorgio Tamburini, Alberto Maleci, Germano Orrù, Luchino Chessa, María Verónica Brasesco
    Open Public Health Journal, 2022
  • HCV treatment in Sardinian HIV-HCV coinfected patients: a real-life perspective study on safety, efficacy, and immune reconstitution
    Francesco Pes, Simona Onali, Cinzia Balestrieri, Goffredo Angioni, Francesco Ortu, Paola Piano, Barca Lucia, Rosetta Scioscia, Elija Princic, Anna Chiara Bolliri, Michele Casale, Alessandra Cola, Maria Conti, Lorenza Peddis, Giancarlo Serra, Stefano Vacca, Martina Loi, Enrico Urru, Claudia Murru, Laura Matta, Stefano Del Giacco, Sergio Babudieri, Ivana Maida, Luchino Chessa
    Expert Review of Anti Infective Therapy, 2022
  • Evaluation of antibody response to heterologous prime–boost vaccination with chadox1 ncov-19 and bnt162b2: An observational study
    Davide Firinu, Andrea Perra, Marcello Campagna, Roberto Littera, Federico Meloni, Francesca Sedda, Maria Conti, Giulia Costanzo, Monica Erbi, Gianmario Usai, Carlotta Locci, Mauro Giovanni Carta, Riccardo Cappai, Germano Orrù, Stefano Del Giacco, Ferdinando Coghe, Luchino Chessa
    Vaccines, 2021
  • Performance of the model for end-stage liver disease score for mortality prediction and the potential role of etiology
    Gennaro D’Amico, Luigi Maruzzelli, Aldo Airoldi, Ioannis Petridis, Giulia Tosetti, Antonio Rampoldi, Mario D’Amico, Roberto Miraglia, Stella De Nicola, Vincenzo La Mura, Marco Solcia, Riccardo Volpes, Giovanni Perricone, Cristiano Sgrazzutti, Angelo Vanzulli, Massimo Primignani, Angelo Luca, Giuseppe Malizia, Alessandro Federico, Marcello Dallio, Angelo Andriulli, Angelo Iacobellis, Luigi Addario, Matteo Garcovich, Antonio Gasbarrini, Luchino Chessa, Francesco Salerno, Giulia Gobbo, Manuela Merli, Lorenzo Ridola, Gianluca Svegliati Baroni, Giuseppe Tarantino, Nicola Caporaso, Filomena Morisco, Pietro Pozzoni, Agostino Colli, Luca Saverio Belli
    Journal of Hepatology, 2021
  • Clinical features and comorbidity pattern of HCV infected migrants compared to native patients in care in Italy: A real-life evaluation of the PITER cohort
    Maria Giovanna Quaranta, Luigina Ferrigno, Xhimi Tata, Franca D'Angelo, Marco Massari, Carmine Coppola, Elisa Biliotti, Alessia Giorgini, Diletta Laccabue, Alessia Ciancio, Pier Luigi Blanc, Marzia Margotti, Donatella Ieluzzi, Maurizia Rossana Brunetto, Francesco Barbaro, Francesco Paolo Russo, Ilaria Beretta, Giulia Morsica, Gabriella Verucchi, Annalisa Saracino, Massimo Galli, Loeta A. Kondili, Cesare Mazzaro, Manuela Bertola, Ornella Schioppa, Antonio Benedetti, Laura Schiadà, Monica Cucco, Andrea Giacometti, Laura Brescini, Sefora Castelletti, Alessandro Fiorentini, Gioacchino Angarano, Michele Milella, Alfredo Di Leo, Maria Rendina, Fulvio Salvatore D'abramo, Chiara Lillo, Andrea Iannone, Mariano Piazzolla, Gabriella Verucchi, Lorenzo Badia, Fabio Piscaglia, Francesca Benevento, Ilaria Serio, Francesco Castelli, Serena Zaltron, Angiola Spinetti, Silvia Odolini, Raffaele Bruno, Mario Mondelli, Luchino Chessa, Martina Loi, Carlo Torti, Chiara Costa, Maria Mazzitelli, Vincenzo Pisani, Vincenzo Scaglione, Enrico Maria Trecarichi, Anna Linda Zignego, Monica Monti, Francesco Madia, Pier Luigi Blanc, Letizia Attala, Piera Pierotti, Elena Salomoni, Elisa Mariabelli, Teresa Antonia Santantonio, Serena Rita Bruno, Ester Marina Cela, Matteo Bassetti, Giovanni Mazzarello, Anna Ida Alessandrini, Antonio Di Biagio, Laura Ambra Nicolini, Giovanni Raimondo, Roberto Filomia, Alessio Aghemo, Rossella Meli, Adriano Lazzarin, Giulia Morsica, Stefania Salpietro, Massimo Galli, Anna Ludovica Fracanzani, Erika Fatta, Rosa Lombardi, Pietro Lampertico, Marta Borghi, Roberta D'ambrosio, Elisabetta Degasperi, Massimo Puoti, Chiara Baiguera, Federico D'amico, Maria Vinci, Maria Grazia Rumi, Massimo Zuin, Alessia Giorgini, Paola Zermiani, Pietro Andreone, Paolo Caraceni, Marzia Margotti, Valeria Guarneri, Erica Villa, Veronica Bernabucci, Laura Bristot, Maria Luisa Paradiso, Guglielmo Migliorino, Ilaria Beretta, Alessandra Gambaro, Giuseppe Lapadula, Anna Spolti, Alessandro Soria, Pietro Invernizzi, Antonio Ciaccio, Martina LucÀ, Federica Malinverno, Laura Ratti, Carmine Coppola, Daniela Caterina Amoruso, Federica Pisano, Ferdinando Scarano, Laura Staiano, Filomena Morisco, Valentina Cossiga, Ivan Gentile, Antonio Riccardo Buonomo, Maria Foggia, Emanuela Zappulo, Alessandro Federico, Marcello Dallio, Nicola Coppola, Caterina Sagnelli, Salvatore Martini, Caterina Monari, Gerardo Nardone, Costantino Sgamato, Liliana Chemello, Luisa Cavalletto, Daniela Sterrantino, Francesco Paolo Russo, Alberto Zanetto, Paola Zanaga, Francesco Barbaro, Giuseppina Brancaccio, Antonio Craxì, Salvatore Petta, Vincenza Calvaruso, Luciano Crapanzano, Salvatore Madonia, Marco Cannizzaro, Erica Maria Bruno, Anna Licata, Simona Amodeo, Adele Rosaria Capitano, Carlo Ferrari, Diletta Laccabue, Elisa Negri, Alessandra Orlandini, Marco Pesci, Roberto Gulminetti, Layla Pagnucco, Giustino Parruti, Paola Di Stefano, Maurizia Rossana Brunetto, Barbara Coco, Marco Massari, Romina Corsini, Elisa Garlassi, Massimo Andreoni, Elisabetta Teti, Carlotta Cerva, Lorenzo Baiocchi, Xhimi Tata, Giuseppe Grassi, Antonio Gasbarrini, Maurizio Pompili, Martina De Siena, Gloria Taliani, Elisa Biliotti, Martina Spaziante, Marcello Persico, Mario Masarone, Andrea Aglitti, Gemma Calvanese, Marco Anselmo, Pasqualina De Leo, Monica Marturano, Giorgio Maria Saracco, Alessia Ciancio, Donatella Ieluzzi
    Digestive and Liver Disease, 2021
  • The COVID-19 incidence in Italian regions correlates with low temperature, mobility and PM10 pollution but lethality only with low temperature
    Mauro Giovanni Carta, Luigi Minerba, Roberto Demontis, Germano Orrù, Ferdinando Romano, Alessandra Scano, Angelo Restivo, Stefano Del Giacco, Simona Deidda, Davide Firinu, Marcello Campagna, Federico Meloni, Giulia Cossu, Federica Sancassiani, Luchino Chessa, Goce Kalcev, Roberto Littera, Luigi Zorcolo, Cesar Ivan Aviles-Gonzales, Paolo Usai
    Journal of Public Health Research, 2021
  • Natural killer-cell immunoglobulin-like receptors trigger differences in immune response to SARS-CoV-2 infection
    Roberto Littera, Luchino Chessa, Silvia Deidda, Goffredo Angioni, Marcello Campagna, Sara Lai, Maurizio Melis, Selene Cipri, Davide Firinu, Simonetta Santus, Alberto Lai, Rita Porcella, Stefania Rassu, Federico Meloni, Daniele Schirru, William Cordeddu, Marta Anna Kowalik, Paola Ragatzu, Monica Vacca, Federica Cannas, Francesco Alba, Mauro Giovanni Carta, Stefano Del Giacco, Angelo Restivo, Simona Deidda, Antonella Palimodde, Paola Congera, Roberto Perra, Germano Orrù, Francesco Pes, Martina Loi, Claudia Murru, Enrico Urru, Simona Onali, Ferdinando Coghe, Sabrina Giglio, Andrea Perra
    Plos One, 2021
  • COVID-19: Considerations about immune suppression and biologicals at the time of SARS-CoV-2 pandemic
    Giulia Costanzo, William Cordeddu, Luchino Chessa, Stefano Del Giacco, Davide Firinu
    World Journal of Clinical Cases, 2021
  • Review article: Safety of new biologic agents for inflammatory bowel disease in the liver
    Salvatore Magrì, Luchino Chessa, Mauro Demurtas, Francesco Cabras, Giammarco Mocci
    European Journal of Gastroenterology and Hepatology, 2021
  • Effectiveness and safety of glecaprevir/pibrentasvir in chronic hepatitis C patients: Results of the Italian cohort of a post-marketing observational study
    Alessio Aghemo, Alfredo Alberti, Pietro Andreone, Mario Angelico, Maurizia Rossana Brunetto, Luchino Chessa, Alessia Ciancio, Antonio Craxì, Giovanni Battista Gaeta, Massimo Galli, Antonio Gasbarrini, Alessia Giorgini, Elisabetta Grilli, Pietro Lampertico, Miriam Lichtner, Michele Milella, Filomena Morisco, Marcello Persico, Mario Pirisi, Massimo Puoti, Giovanni Raimondo, Antonietta Romano, Maurizio Russello, Vincenzo Sangiovanni, Monica Schiavini, Gaetano Serviddio, Erica Villa, Maria Vinci, Antonella De Michina, Valentina Gallinaro, Giuliana Gualberti, Antonio Saverio Roscini, Anna Linda Zignego
    Digestive and Liver Disease, 2021
  • The impact of DAA-mediated HCV eradication on CD4+ and CD8+ T lymphocyte trajectories in HIV/HCV coinfected patients: Data from the ICONA Foundation Cohort
    Alessandra Bandera, Patrizia Lorenzini, Lucia Taramasso, Alessandro Cozzi‐Lepri, Giuseppe Lapadula, Cristina Mussini, Annalisa Saracino, Francesca Ceccherini‐Silberstein, Massimo Puoti, Eugenia Quiros‐Roldan, Francesca Montagnani, Andrea Antinori, A. d’Arminio Monforte, Andrea Gori, M Andreoni, A Castagna, F Castelli, R Cauda, G Di Perri, M Galli, R Iardino, G Ippolito, A Lazzarin, GC Marchetti, G Rezza, F von Shloesser, P Viale, A Castagna, E Girardi, S Lo Caputo, F Maggiolo, CF Perno, F Bai, S Bonora, M Borderi, A Calcagno, MR Capobianchi, A Castagna, S Cicalini, A Cingolani, P Cinque, A Di Biagio, R Gagliardini, E Girardi, N Gianotti, G Guaraldi, M Lichtner, A Lai, G Madeddu, F Maggiolo, G Marchetti, E Merlini, S Nozza, CF Perno, S Piconi, C Pinnetti, R Rossotti, S Rusconi, MM Santoro, L Sarmati, V Spagnuolo, V Svicher, I Fanti, L Galli, A Rodano’, M Macchia, A Tavelli, A Bove, A Camposeragna, M Errico, M Manfredini, A Perziano, V Calvino, F Carletti, S Carrara, A Di Caro, S Graziano, F Petroni, G Prota, S Truffa, A Giacometti, A Costantini, V Barocci, G Angarano, L Monno, E Milano, F Maggiolo, C Suardi, P Viale, V Donati, G Verucchi, F Castelnuovo, C Minardi, B Menzaghi, C Abeli, L Chessa, F Pes, B Cacopardo, B Celesia, J Vecchiet, K Falasca, A Pan, S Lorenzotti, L Sighinolfi, D Segala, P Blanc, F Vichi, G Cassola, M Bassetti, A Alessandrini, N Bobbio, G Mazzarello, M Lichtner, L Fondaco, P Bonfanti, C Molteni, A Chiodera, P Milini, G Nunnari, G Pellicanò, M Galli, A Lazzarin, G Rizzardini, A Castagna, ES Cannizzo, MC Moioli, R Piolini, D Bernacchia, A Poli, C Tincati, C Puzzolante, C Migliorino, V Sangiovanni, G Borgia, V Esposito, G Di Flumeri, I Gentile, V Rizzo, AM Cattelan, S Marinello, A Cascio, M Trizzino, D Francisci, E Schiaroli, G Parruti, F Sozio, C Lazzaretti, R Corsini, M Andreoni, R Cauda, A Cristaudo, V Vullo, R Acinapura, S Lamonica, M Capozzi, A Mondi, A Cingolani, M Rivano Capparuccia, G Iaiani, A Latini, G Onnelli, MM Plazzi, G De Girolamo, A Vergori, M Cecchetto, F Viviani, G Madeddu, A De Vito, B Rossetti, A Franco, R Fontana Del Vecchio, C Di Giuli, P Caramello, G Di Perri, S Bonora, GC Orofino, M Sciandra, A Londero, V Manfrin, G Battagin, G Starnini, A Ialungo, and
    Journal of Viral Hepatitis, 2021
  • Real-world experience with obeticholic acid in patients with primary biliary cholangitis
    Daphne D’Amato, Antonio De Vincentis, Federica Malinverno, Mauro Viganò, Domenico Alvaro, Maurizio Pompili, Antonino Picciotto, Valeria Pace Palitti, Maurizio Russello, Silvia Storato, Marie Graciella Pigozzi, Vincenza Calvaruso, Elisabetta De Gasperi, Ana Lleo, Antonino Castellaneta, Adriano Pellicelli, Nora Cazzagon, Annarosa Floreani, Luigi Muratori, Stefano Fagiuoli, Grazia Anna Niro, Valentina Feletti, Raffaele Cozzolongo, Natalia Terreni, Marco Marzioni, Rinaldo Pellicano, Pietro Pozzoni, Leonardo Baiocchi, Luchino Chessa, Floriano Rosina, Gaetano Bertino, Maria Vinci, Anna Morgando, Ester Vanni, Gaetano Scifo, Rodolfo Sacco, Maria D’Antò, Valentina Bellia, Roberto Boldizzoni, Silvia Casella, Barbara Omazzi, Guido Poggi, Laura Cristoferi, Alessio Gerussi, Vincenzo Ronca, Rosanna Venere, Francesca Ponziani, Maria Cannavò, Alessandro Mussetto, Rosanna Fontana, Francesco Losito, Evelise Frazzetto, Marco Distefano, Francesca Colapietro, Sara Labanca, Giulia Marconi, Giuseppe Grassi, Giovanni Galati, Sarah Elizabeth O’Donnell, Clara Mancuso, Giacomo Mulinacci, Andrea Palermo, Ernesto Claar, Antonio Izzi, Antonio Picardi, Pietro Invernizzi, Marco Carbone, Umberto Vespasiani-Gentilucci
    Jhep Reports, 2021
  • Gastrointestinal coronavirus disease 2019: epidemiology, clinical features, pathogenesis, prevention, and management
    Simona Deidda, Lorena Tora, Davide Firinu, Stefano Del Giacco, Marcello Campagna, Federico Meloni, Germano Orrù, Luchino Chessa, Mauro Giovanni Carta, Alessandra Melis, Gaya Spolverato, Roberto Littera, Andrea Perra, Simona Onali, Luigi Zorcolo, Angelo Restivo
    Expert Review of Gastroenterology and Hepatology, 2021
  • Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience
    Roberto Littera, Marcello Campagna, Silvia Deidda, Goffredo Angioni, Selene Cipri, Maurizio Melis, Davide Firinu, Simonetta Santus, Alberto Lai, Rita Porcella, Sara Lai, Stefania Rassu, Rosetta Scioscia, Federico Meloni, Daniele Schirru, William Cordeddu, Marta Anna Kowalik, Maria Serra, Paola Ragatzu, Mauro Giovanni Carta, Stefano Del Giacco, Angelo Restivo, Simona Deidda, Sandro Orrù, Antonella Palimodde, Roberto Perra, Germano Orrù, Maria Conti, Cinzia Balestrieri, Giancarlo Serra, Simona Onali, Francesco Marongiu, Andrea Perra, Luchino Chessa
    Frontiers in Immunology, 2020
  • Evaluation of HIV transmission clusters among natives and foreigners living in Italy
    Lavinia Fabeni, Maria Mercedes Santoro, Patrizia Lorenzini, Stefano Rusconi, Nicola Gianotti, Andrea Costantini, Loredana Sarmati, Andrea Antinori, Francesca Ceccherini-Silberstein, Antonella d’Arminio Monforte, Annalisa Saracino, Enrico Girardi, and
    Viruses, 2020
  • Advanced liver disease outcomes after hepatitis C eradication by human immunodeficiency virus infection in PITER cohort
    Maria Giovanna Quaranta, , Luigina Ferrigno, Monica Monti, Roberto Filomia, Elisa Biliotti, Andrea Iannone, Guglielmo Migliorino, Barbara Coco, Filomena Morisco, Maria Vinci, Roberta D’Ambrosio, Liliana Chemello, Marco Massari, Donatella Ieluzzi, Francesco Paolo Russo, Pierluigi Blanc, Gabriella Verucchi, Massimo Puoti, Maria Grazia Rumi, Francesco Barbaro, Teresa Antonia Santantonio, Alessandro Federico, Luchino Chessa, Ivan Gentile, Massimo Zuin, Giustino Parruti, Giulia Morsica, Loreta A. Kondili
    Hepatology International, 2020
  • The climate in the european union and the enlarged european region is a determinant of the covid-19 case fatality ratio
    G. Orrù, F. Romano, A. Scano, A. Restivo, S. Giacco, S. Deidda, D. Firinu, M. Campagna, G. Cossu, L. Chessa, G. Kalcev, M. Carta
    Biointerface Research in Applied Chemistry, 2020
  • Is the inversion in the trend of the lethality of the covid-19 in the two hemispheres due to the difference in seasons and weather?
    M. Carta, G. Kalcev, A. Scano, F. Romano, G. Cossu, R. Littera, A. Perra, S. Deidda, D. Firinu, S. Giacco, M. Campagna, L. Chessa, L. Zorcolo, A. Restivo, G. Orrù
    Biointerface Research in Applied Chemistry, 2020
  • Entropy of human leukocyte antigen and killer-cell immunoglobulin-like receptor systems in immune-mediated disorders: A pilot study on multiple sclerosis
    Maurizio Melis, Roberto Littera, Eleonora Cocco, Jessica Frau, Sara Lai, Elena Congeddu, Paola Ragatzu, Maria Serra, Valentina Loi, Roberta Maddi, Roberta Pitzalis, Sandro Orrù, Luchino Chessa, Andrea Perra, Carlo Carcassi
    Plos One, 2019
  • Rate of non-response to ursodeoxycholic acid in a large real-world cohort of primary biliary cholangitis patients in Italy
    Umberto Vespasiani-Gentilucci, Floriano Rosina, Valeria Pace-Palitti, Rodolfo Sacco, Adriano Pellicelli, Luchino Chessa, Antonio De Vincentis, Michela Barlattani, Angelo Barlattani, Valentina Feletti, Alessandro Mussetto, Teresa Zolfino, Maurizio Russello, Raffaele Cozzolongo, Giovanni Garrucciu, Grazia Niro, Donato Bacca, Gaetano Bertino, Ernesto Claar, Antonio Ascione, Giuseppe D’Adamo, Luigi Elio Adinolfi, Gaetano Scifo, Antonio Izzi, for the CLEO-AIGO PBC study group
    Scandinavian Journal of Gastroenterology, 2019
  • HepaDisk – A new quality of life questionnaire for HCV patients
    Stefano Fagiuoli, Nicola Caporaso, Filomena Morisco, Fabio Buelli, Giuliana Gualberti, Valeria Saragaglia, Luchino Chessa, Giampaolo Corti, Ivana Maida, Claudio M. Mastroianni, Mario Pirisi, Francesco P. Russo, Francesca Farina, Lydia Giannitrapani, Pierluigi Toniutto, Pierluigi Tarquini, Paolo Tundo, Jacopo Vecchiet, Maria Vinci, Gloria Taliani
    Digestive and Liver Disease, 2019
  • Economic Consequences of Investing in Anti-HCV Antiviral Treatment from the Italian NHS Perspective: A Real-World-Based Analysis of PITER Data
    PITER Collaborating group available at www.progettopiter.it, Andrea Marcellusi, Raffaella Viti, Loreta A. Kondili, Stefano Rosato, Stefano Vella, Francesco Saverio Mennini
    Pharmacoeconomics, 2019
  • Impact of direct-acting antiviral drugs for chronic hepatitis C on mood: Preliminary results from a longitudinal study
    Gioia Mura, Luchino Chessa, Annaraffaela Manca, Antonio Preti, Cinzia Balestrieri, Simona Onali, Mauro Giovanni Carta
    General Hospital Psychiatry, 2019
  • Add-on peginterferon alfa-2a to nucleos(t)ide analogue therapy for Caucasian patients with hepatitis B ‘e’ antigen-negative chronic hepatitis B genotype D
    Pietro Lampertico, Maurizia R. Brunetto, Antonio Craxì, Giovanni B. Gaeta, Mario Rizzetto, Antonella Rozzi, Massimo Colombo, on behalf of The HERMES Study Group
    Journal of Viral Hepatitis, 2019
  • Forecasting Hepatitis C liver disease burden on real-life data. Does the hidden iceberg matter to reach the elimination goals?
    Loreta A. Kondili, Sarah Robbins, Sarah Blach, Ivane Gamkrelidze, Anna L. Zignego, Maurizia R. Brunetto, Giovanni Raimondo, Gloria Taliani, Andrea Iannone, Francesco P. Russo, Teresa A. Santantonio, Massimo Zuin, Luchino Chessa, Pierluigi Blanc, Massimo Puoti, Maria Vinci, Elke M. Erne, Mario Strazzabosco, Marco Massari, Pietro Lampertico, Maria G. Rumi, Alessandro Federico, Alessandra Orlandini, Alessia Ciancio, Guglielmo Borgia, Pietro Andreone, Nicola Caporaso, Marcello Persico, Donatella Ieluzzi, Salvatore Madonia, Andrea Gori, Antonio Gasbarrini, Carmine Coppola, Giuseppina Brancaccio, Angelo Andriulli, Maria G. Quaranta, Simona Montilla, Homie Razavi, Mario Melazzini, Stefano Vella, Antonio Craxì, PITER Collaborating Group
    Liver International, 2018
  • Safety and efficacy of ombitasvir/paritaprevir/ritonavir/dasabuvir plus ribavirin in patients over 65 years with HCV genotype 1 cirrhosis
    Antonio Ascione, Massimo De Luca, Mario Melazzini, Simona Montilla, Maria Paola Trotta, Salvatore Petta, Massimo Puoti, Vincenzo Sangiovanni, Vincenzo Messina, Savino Bruno, Antonio Izzi, Erica Villa, Alessio Aghemo, Anna Linda Zignego, Alessandra Orlandini, Luca Fontanella, Antonio Gasbarrini, Marco Marzioni, Edoardo G. Giannini, Antonio Craxì, For the ABACUS Study Group, Giuseppe Abbati, Alfredo Alberti, Pietro Andreone, Massimo Andreoni, Paolo Angeli, Mario Angelico, Gioacchino Angarano, Debora Angrisani, Andrea Antinori, Cinzia Antonini, Ivo Avancini, Michele Barone, Raffaele Bruno, Antonio Benedetti, Veronica Bernabucci, Pier Blanc, Chiara Boarini, Nicola Boffa, Lucio Boglione, Vanni Borghi, Guglielmo Borgia, Giuseppina Brancaccio, Maurizia Brunetto, Irene Cacciola, Paolo Calabrese, Vincenza Calvaruso, Davide Campagnolo, Benedetta Canovari, Nicola Caporaso, Franco Capra, Giada Carolo, Giovanni Cassola, Francesco Castelli, Roberto Cauda, Francesca Ceccherini Silberstein, Roberto Cecere, Luchino Chessa, Alessandro Chiodera, Antonio Chirianni, Alessia Ciancio, Serena Cima, Barbara Coco, Massimo Colombo, Nicola Coppola, Giampaolo Corti, Lucio Cosco, Silvia Corradori, Raffaele Cozzolongo, Antonio Cristaudo, Elena Danieli, Antonella D’Arminio Monforte, Marco delle Monache, Paolo Del Poggio, Andrea de Luca, Chiara Dentone, Antonio Di Biagio, Alfredo Di Leo, Giovanni Di Perri, Marco Di Stefano, Giampiero D’Offizi, Francesca Donato, Emanuele Durante, Elke Erne, Stefano Fagiuoli, Katia Falasca, Alessandro Federico, Martina Felder, Carlo Ferrari, Giovanni Battista Gaeta, Roberto Ganga, Pietro Gatti, Vania Giacomet, Andrea Giacometti, Alice Gianstefani, Maria Giordani, Alessia Giorgini, Antonio Grieco, Michele Guerra, Roberto Gulminetti, Donatella Ieluzzi, Michele Imparato, Valentina Iodice, Silvia La Monica, Adriano Lazzarin, Marco Lenzi, Massimo Levrero, Myriam Lichtner, Raffaella Lionetti, Carmela Lo Guercio, Salvatore Madonna, Silvia Magnani, Ivana Maida, Massimo Marignani, Aldo Marrone, Fabio Marsetti, Silvia Martini, Mario Masarone, Renato Maserati, Claudio Maria Mastroianni, Massimo Memoli, Barbara Menzaghi, Manuela Merli, Luca Miele, Michele Milella, Mario Mondelli, Marzia Montalbano, Monica Monti, Olivia Morelli, Filomena Morisco, Gaetano Nardone, Sergio Novara, Giovanna Onnelli, Mirella Onofrio, Simona Paganin, Luca Pani, Maria Rita Parisi, Giustino Parruti, Caterina Pasquazzi, Luisa Pasulo, Carlo Federico Perno, Marcello Persico, Guido Piai, Antonino Picciotto, Grazielle Marie Pigozzi, Sara Piovesan, Maria Chiara Piras, Massimo Pirisi, Anna Maria Piscaglia, Laura Ponti, Domenico Potenza, Cecilia Pravadelli, Mariano Quartini, Tiziana Quirino, Giovanni Raimondo, Gian Ludovico Rapaccini, Maria Rendina, Giuliano Rizzardini, Mario Rizzetto, Salvatore Rizzo, Dante Romagnoli, Antonietta Romano, Cristina Rossi, Maria Grazia Rumi, Maurizio Russello, Francesca Paolo Russo, Maria Luisa Russo, Domenico Ettore Sansonno, Teresa Antonia Santantonio, Giorgio Saracco, Anna Maria Schimizzi, Gaetano Serviddio, Filomena Simeone, Attilio Solinas, Alessandro Soria, Marco Tabone, Gloria Taliani, Giuseppe Tarantino, Pierluigi Tarquini, Marcello Tavio, Antonio Termite, Elisabetta Teti, Pierluigi Toniutto, Carlo Torti, Paolo Tundi, Giacomo Vecchiet, Gabriella Verucchi, Umberto Vespasiani Gentilucci, Maria Vinci, Vincenzo Vullo, Teresa Zolfino, Massimo Zuin
    Infection, 2018
  • Corrigendum to “Premature ovarian senescence and a high miscarriage rate impair fertility in women with HCV” [J Hepatol 68 (2018) 33–41](S0168827817322596)(10.1016/j.jhep.2017.08.019)
    Aimilia Karampatou, Xue Han, Loreta A. Kondili, Gloria Taliani, Alessia Ciancio, Filomena Morisco, Rosina Maria Critelli, Enrica Baraldi, Veronica Bernabucci, Giulia Troshina, Maria Guarino, Simonetta Tagliavini, Federica D'Ambrosio, Laura Bristot, Laura Turco, Stefano Rosato, Stefano Vella, Tommaso Trenti, Isabella Neri, Antonio La Marca, Shivaji Manthena, Andrea S. Goldstein, Savino Bruno, Yanjun Bao, Yuri Sanchez Gonzalez, Erica Villa
    Journal of Hepatology, 2018
  • Safety and efficacy of direct-acting antivirals in transfusion-dependent thalassemic patients with chronic hepatitis C
    Simona Onali, Ivana Maida, Cinzia Balestrieri, Francesco Arcadu, Enrico Urru, Davide Porcu, Giancarlo Serra, Giacomo Flore, Elena Dore, Caterina Satta, Pier Paolo Bitti, Maria Grazia Sanna, Loredana Serusi, Michele Casale, Maria Conti, Martina Loi, Francesco Figorilli, Maria Cristina Pasetto, Sergio Babudieri, Luchino Chessa
    Hepatitis Monthly, 2018
  • Bone mass preservation with high-dose cholecalciferol and dietary calcium in HIV patients following antiretroviral therapy. Is it possible?
    Quirico Mela, Valeria Ruggiero, Lorenza Montaldo, Umberto Pisano, Laura Matta, Cristina Maria Pasetto, Simona Onali, Enrico Cacace, Mauro Giovanni Carta, Lucia Barca, Luchino Chessa
    HIV Clinical Trials, 2018
  • Multicenter prospective study of angiogenesis polymorphism validation in HCC patients treated with sorafenib. An INNOVATE study protocol
    Andrea Casadei Gardini, Luca Faloppi, Giuseppe Aprile, Oronzo Brunetti, Chiara Caparello, Jody Corbelli, Luchino Chessa, Daniele Bruno, Giorgio Ercolani, Alessandro Leonetti, Giorgio de Stefano, Nunzia Farella, Francesco Giuseppe Foschi, Arianna Lanzi, Vincenzo Dadduzio, Giorgia Marisi, Gianluca Masi, Francesca V. Negri, Flavia Pagan, Daniele Santini, Emanuela Scarpi, Marianna Silletta, Nicola Silvestris, Emiliano Tamburini, Davide Tassinari, Caterina Vivaldi, Umberto Vespasiani Gentilucci, Vittorina Zagonel, Lorenzo Calvetti, Stefano Cascinu, Giovanni Luca Frassineti, Mario Scartozzi
    Tumori, 2018
  • Premature ovarian senescence and a high miscarriage rate impair fertility in women with HCV
    Aimilia Karampatou, Xue Han, Loreta A. Kondili, Gloria Taliani, Alessia Ciancio, Filomena Morisco, Rosina Maria Critelli, Enrica Baraldi, Veronica Bernabucci, Giulia Troshina, Maria Guarino, Simonetta Tagliavini, Federica D'Ambrosio, Laura Bristot, Laura Turco, Stefano Rosato, Stefano Vella, Tommaso Trenti, Isabella Neri, Antonio La Marca, Shivaji Manthena, Andrea S. Goldstein, Savino Bruno, Yanjun Bao, Yuri Sanchez Gonzalez, Erica Villa, A. Craxì, S. Petta, V. Calvaruso, M. Brunetto, B. Coco, L. Chessa, M.C. Pasetto, E. Bigliotti, F. Tamburrini, G. Montalto, A.R. Capitano, D. Ieluzzi, G. Fattovich, A.L. Zignego, M. Monti, L. Gragnani, M. Zuin, E. Finati, A. Giorgini, G. Angarano, M. Milella, F. Alessandro, M. Dallio, G. Mazzella, G. Lazzarini, M. Di Fine, F.P. Russo, A. Zanetto, F. Castelli, S. Zaltron, G. Raimondo, R. Filomia, M. Puoti, E. Danieli, M. Strazzabosco, M. Gemma, M. Angelico, F. De Leonardis, A. Gori, E. Cappelletti, R. Bruno, S. Cima, C. Coppola, D.C. Amoruso, P. Andreone, G. Simonetti, G.B. Gaeta, G. Brancaccio, P. Toniutto, D. Dissegna, M. Mondelli, S. Ludovisi, M. Persico, M. Masarone, C. Torti, A. Strazzulla, F. Rosina, L. Framarin, L.E. Weimer, M.G. Quaranta, L. Falzano, A. Mallano
    Journal of Hepatology, 2018
  • Modeling cost-effectiveness and health gains of a “universal” versus “prioritized” hepatitis C virus treatment policy in a real-life cohort
    Loreta A. Kondili, Federica Romano, Francesca Romana Rolli, Matteo Ruggeri, Stefano Rosato, Maurizia Rossana Brunetto, Anna Linda Zignego, Alessia Ciancio, Alfredo Di Leo, Giovanni Raimondo, Carlo Ferrari, Gloria Taliani, Guglielmo Borgia, Teresa Antonia Santantonio, Pierluigi Blanc, Giovanni Battista Gaeta, Antonio Gasbarrini, Luchino Chessa, Elke Maria Erne, Erica Villa, Donatella Ieluzzi, Francesco Paolo Russo, Pietro Andreone, Maria Vinci, Carmine Coppola, Liliana Chemello, Salvatore Madonia, Gabriella Verucchi, Marcello Persico, Massimo Zuin, Massimo Puoti, Alfredo Alberti, Gerardo Nardone, Marco Massari, Giuseppe Montalto, Giuseppe Foti, Maria Grazia Rumi, Maria Giovanna Quaranta, Americo Cicchetti, Antonio Craxì, Stefano Vella, on behalf of the PITER Collaborating Group
    Hepatology, 2017
  • Awareness, discussion and non-prescribed use of HIV pre-exposure prophylaxis among persons living with HIV/AIDS in Italy: A Nationwide, cross-sectional study among patients on antiretrovirals and their treating HIV physicians
    the PrEPventHIV Italy Study Group, Antonio Palummieri, Gabriella De Carli, Éric Rosenthal, Patrice Cacoub, Cristina Mussini, Vincenzo Puro
    BMC Infectious Diseases, 2017
  • Incidence of DAA failure and the clinical impact of retreatment in real-life patients treated in the advanced stage of liver disease: Interim evaluations from the PITER network
    Loreta A. Kondili, Giovanni Battista Gaeta, Maurizia Rossana Brunetto, Alfredo Di Leo, Andrea Iannone, Teresa Antonia Santantonio, Adele Giammario, Giovanni Raimondo, Roberto Filomia, Carmine Coppola, Daniela Caterina Amoruso, Pierluigi Blanc, Barbara Del Pin, Liliana Chemello, Luisa Cavalletto, Filomena Morisco, Laura Donnarumma, Maria Grazia Rumi, Antonio Gasbarrini, Massimo Siciliano, Marco Massari, Romina Corsini, Barbara Coco, Salvatore Madonia, Marco Cannizzaro, Anna Linda Zignego, Monica Monti, Francesco Paolo Russo, Alberto Zanetto, Marcello Persico, Mario Masarone, Erica Villa, Veronica Bernabucci, Gloria Taliani, Elisa Biliotti, Luchino Chessa, Maria Cristina Pasetto, Pietro Andreone, Marzia Margotti, Giuseppina Brancaccio, Donatella Ieluzzi, Guglielmo Borgia, Emanuela Zappulo, Vincenza Calvaruso, Salvatore Petta, Loredana Falzano, Maria Giovanna Quaranta, Liliana Elena Weimer, Stefano Rosato, Stefano Vella, Edoardo Giovanni Giannini
    Plos One, 2017
  • Distribution of IL28B Polymorphism in a Cohort of Italians and Immigrants with HCV Infection: Association with Viraemia, Stage of Fibrosis and Response to Treatment
    L. Nosotti, A. Petrelli, D. Genovese, S. Catone, C. Argentini, S. Vella, A. Rossi, G. Costanzo, A. Fortino, L. Chessa, L. Miglioresi, C. Mirisola
    Journal of Immigrant and Minority Health, 2017
  • Ombitasvir, paritaprevir, and ritonavir, with or without dasabuvir, plus ribavirin for patients with hepatitis C virus genotype 1 or 4 infection with cirrhosis (ABACUS): a prospective observational study
    Salvatore Petta, Marco Marzioni, Pierluigi Russo, Alessio Aghemo, Alfredo Alberti, Antonio Ascione, Andrea Antinori, Raffaele Bruno, Savino Bruno, Antonio Chirianni, Giovanni Battista Gaeta, Edoardo G Giannini, Manuela Merli, Vincenzo Messina, Simona Montilla, Carlo Federico Perno, Massimo Puoti, Giovanni Raimondo, Maria Rendina, Francesca Ceccherini Silberstein, Erica Villa, Anna Linda Zignego, Luca Pani, Antonio Craxì, Marco Tabone, Massimo Andreoni, Elisabetta Teti, Mario Angelico, Marcello Persico, Mario Masarone, Aledssandro Chiodera, Attilio Solinas, Marco delle Monache, Roberto Cecere, Anna Maria Schimizzi, Sara Piovesan, Davide Campagnolo, Maria Chiara Piras, Teresa Zolfino, Francesca Paolo Russo, Olivia Morelli, Vincenzo Sangiovanni, Mirella Onofrio, Valentina Iodice, Antonio Izzi, Massimo Pirisi, Elena Danieli, Maria Vinci, Giuliano Rizzardini, Stefano Fagiuoli, Luisa Pasulo, Antonella D'Arminio Monforte, Massimo Zuin, Alessia Giorgini, Filomena Simeone, Guido Piali, Carmela Lo Guercio, Alessandro Federico, Giuseppina Brancaccio, Aldo Marrone, Giuseppe Abbati, Chiara Boarini, Vanni Borghi, Veronica Bernabucci, Giampaolo Corti, Monica Monti, Mario Rizzetto, Silvia Martini, Pietro Andreone, Alice Gianstefani, Marco Lenzi, Gabriella Verucchi, Pierluigi Toniutto, Guglielmo Borgia, Nicola Caporaso, Filomena Morisco, Gaetano Nardone, Debora Angrisani, Andrea Giacometti, Antonio Benedetti, Giuseppe Tarantino, Fabio Marsetti, Marcello Tavio, Sergio Novara, Teresa Antonia Santantonio, Gaetano Serviddio, Maurizia Brunetto, Barbara Coco, Gioacchino Angarano, Michele Milella, Michele Barone, Alfredo Di Leo, Domenico Ettore Sansonno, Irene Cacciola, Nicola Boffa, Giorgio Saracco, Antonio Di Biagio, Antonino Picciotto, Andrea de Luca, Vincenza Calvaruso, Silvia Corradori, Carlo Ferrari, Alessandra Orlandini, Ivana Maida, Carlo Torti, Luchino Chessa, Martina Felder, Umberto Vespasiani Gentilucci, Paolo Angeli, Antonietta Romano, Gian Ludovico Rapaccini, Luca Miele, Serena Cima, Maria Luisa Russo, Raffaele Cozzolongo, Giovanna Onnelli, Giampiero D'Offizi, Raffaella Lionetti, Marzia Montalbano, Michele Guerra, Giovanni Di Perri, Lucio Boglione, Franco Capra, Giada Carolo, Donatella Ieluzzi, Cinzia Antonini, Antonio Termite, Salvatore Madonia, Pierluigi Tarquini, Giustino Parruti, Giacomo Vecchiet, Katia Falasca, Barbara Menzaghi, Tiziana Quirino, Chiara Dentone, Anna Maria Piscaglia, Cristina Rossi, Maria Giordani, Luca Fontanella, Giovanni Cassola, Maurizio Russello, Antonio Cristaudo, Vania Giacomet, Massimo Colombo, Francesca Donato, Emanuele Durante, Lucio Cosco, Massimo Marignani, Mariano Quartini, Massimo Memoli, Roberto Ganga, Laura Ponti, Alessandro Soria, Maria Grazia Rumi, Roberto Gulminetti, Renato Maserati, Mario Mondelli, Adriano Lazzarin, Maria Rita Parisi, Benedetta Canovari, Ivo Avancini, Cecilia Pravadelli, Pier Blanc, Caterina Pasquazzi, Claudio Maria Mastroianni, Myriam Lichtner, Marco Distefano, Silvia Magnani, Simona Paganin, Elke Erne, Pietro Gatti, Paolo Tundi, Paolo Calabrese, Antonio Gasbarrini, Antonio Grieco, Nicola Coppola, Paolo Del Poggio, Massimo Levrero, Gloria Talliani, Vincenzo Vullo, Roberto Cauda, Silvia La Monica, Domenico Potenza, Salvatore Rizzo, Francesco Castelli, Grazielle Marie Pigozzi, Alessia Ciancio, Dante Romagnoli, Federica Barchetti, Jelena Ivanovic, Olimpia Longo, Sandra Petraglia, Maria Paola Trotta
    Lancet Gastroenterology and Hepatology, 2017
  • The prevalence of bright liver echo pattern in patients with chronic hepatitis C: correlation with steatosis and fibrosis
    Maurizio Loy, Giancarlo Serra, Luchino Chessa
    Journal of Ultrasound, 2016
  • Exploring the role of killer cell immunoglobulin-like receptors and their HLA class I ligands in autoimmune hepatitis
    Roberto Littera, Luchino Chessa, Simona Onali, Francesco Figorilli, Sara Lai, Luca Secci, Giorgio La Nasa, Giovanni Caocci, Marcella Arras, Maurizio Melis, Sara Cappellini, Cinzia Balestrieri, Giancarlo Serra, Maria Conti, Teresa Zolfino, Michele Casale, Stefania Casu, Maria Cristina Pasetto, Lucia Barca, Claudia Salustro, Laura Matta, Rosetta Scioscia, Fausto Zamboni, Gavino Faa, Sandro Orrù, Carlo Carcassi
    Plos One, 2016
  • Can antiretroviral therapy modify the clinical course of HDV infection in HIV-positive patients?
    Simona Onali, Francesco Figorilli, Cinzia Balestrieri, Giancarlo Serra, Maria Conti, Rosetta Scioscia, Lucia Barca, Maria E Lai, Luchino Chessa
    Antiviral Therapy, 2015
  • Absence of activating killer immunoglobulin-like receptor genes combined with hepatitis C viral genotype is predictive of hepatocellular carcinoma
    Roberto Littera, Fausto Zamboni, Vincenzo Tondolo, Giovanni Fantola, Luchino Chessa, Nicola Orrù, Marco Sanna, Donatella Valentini, Luisella Cappai, Marina Mulargia, Giovanni Caocci, Marcella Arras, Andrea Floris, Sandro Orrù, Giorgio La Nasa, Carlo Carcassi
    Human Immunology, 2013
  • Randomised study comparing 48 and 96 weeks peginterferon α-2a therapy in genotype D HBeAg-negative chronic hepatitis B
    Pietro Lampertico, Mauro Viganò, Giovan Giuseppe Di Costanzo, Evangelista Sagnelli, Massimo Fasano, Vito Di Marco, Sara Boninsegna, Patrizia Farci, Silvia Fargion, Tiziana Giuberti, Claudio Iannacone, Loredana Regep, Benedetta Massetto, Floriana Facchetti, Massimo Colombo, on behalf of the PegBeLiver Study Group
    Gut, 2013
  • Association of chronic hepatitis C with recurrent brief depression
    Mauro G. Carta, Jules Angst, Maria Francesca Moro, Gioia Mura, Maria Carolina Hardoy, Cinzia Balestrieri, Luchino Chessa, Giancarlo Serra, Maria Eliana Lai, Patrizia Farci
    Journal of Affective Disorders, 2012
  • Hepatitis C in the elderly: A multicentre cross-sectional study by the Italian Association for the Study of the Liver
    Annagiulia Gramenzi, Fabio Conti, Calogero Cammà, Antonio Grieco, Antonino Picciotto, Caterina Furlan, Domenico Romagno, Paolo Costa, Maria Rendina, Fausto Ancarani, Maria Chiaramonte, Gabriella Verucchi, Antonio Craxì, Mauro Bernardi, Pietro Andreone
    Digestive and Liver Disease, 2012
  • Treatment of chronic hepatitis B: Recommendations from an Italian workshop
    G. Carosi, M. Rizzetto
    Digestive and Liver Disease, 2008
  • Treatment of chronic hepatitis D
    P. Farci, L. Chessa, C. Balestrieri, G. Serra, M. E. Lai
    Journal of Viral Hepatitis, 2007
  • Association of chronic hepatitis C with major depressive disorders: Irrespective of interferon-alpha therapy
    Mauro G Carta, Maria Hardoy, Alessandra Garofalo, Enrica Pisano, Valentina Nonnoi, Gesuina Intilla, Giancarlo Serra, Cinzia Balestrieri, Luchino Chessa, Cristiana Cauli, Maria Lai, Patrizia Farci
    Clinical Practice and Epidemiology in Mental Health, 2007
  • Treatment of chronic hepatitis C in patients with glucose-6-phosphate dehydrogenase deficiency: Is ribavirin harmful? [3]
    Cinzia Balestrieri, Giancarlo Serra, Cristiana Cauli, Luchino Chessa, Angelo Balestrieri, Patrizia Farci
    Blood, 2006
  • Severe autoimmune hemolytic anemia in a patient with chronic hepatitis C during treatment with peginterferon alfa-2a and ribavirin.
    Haematologica, 2006
  • Hepatitis and psychiatric symptoms
    Italian Journal of Psychopathology, 2005
  • Interferon-alpha-induced psychiatric side effects in patients with chronic viral hepatitis: A prospective, observational, controlled study
    M. Germana Orrù, Antonella Baita, Rossella Sitzia, Alessandra Costa, Elisabetta Muntoni, Sabine Landau, Luchino Chessa, M. Giulia Farci, Bernardo Carpiniello, Carmine M. Pariante
    Epidemiologia E Psichiatria Sociale, 2005
  • Long-term benefit of interferon α therapy of chronic hepatitis D: Regression of advanced hepatic fibrosis
    Patrizia Farci, Tania Roskams, Luchino Chessa, Giovanna Peddis, Anna Paola Mazzoleni, Rosetta Scioscia, Giancarlo Serra, Maria Eliana Lai, Maurizio Loy, Luciano Caruso
    Gastroenterology, 2004
  • Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome
    Patrizia Farci, Rita Strazzera, Harvey J. Alter, Stefania Farci, Daniela Degioannis, Alessandra Coiana, Giovanna Peddis, Francesco Usai, Giancarlo Serra, Luchino Chessa, Giacomo Diaz, Angelo Balestrieri, Robert H. Purcell
    Proceedings of the National Academy of Sciences of the United States of America, 2002
  • The quasispecies nature of hepatitis C virus: Biological and clinical implications
    Argomenti Di Gastroenterologia Clinica, 1998
  • Urinary neopterine: a new tool in the progression from ARC to AIDS
    EOS Rivista Di Immunologia Ed Immunofarmacologia, 1990

RECENT SCHOLAR PUBLICATIONS

  • Risk of developing low-level viral rebound (LLVR) among people with HIV (PWH) receiving two or three drug regimens: a case control study nested in the ICONA cohort
    A Vergori, A Cervo, A Roen, R Gagliardini, T Clemente, V Mazzotta, ...
    Open Forum Infectious Diseases, ofag250 , 2026
    2026
  • Proportion of newly diagnosed persons with HIV with HIV-RNA greater than/equal to 500 000 copies/mL in 2018–2023 in Italy: data from the ICONA Foundation Cohort Study
    AA Monforte, N Lentini, A Tavelli, S Rusconi, F Sozio, A Guida, E Zappulo, ...
    Clinical Microbiology and Infection 32 (5), 866-869 , 2026
    2026
  • Real-world experience of fibrates as second-line therapies in patients with primary biliary cholangitis: data from the Italian PBC Registry
    L Cristoferi, E Nofit, A Nardi, N Cazzagon, E Bonaiuto, P Lampertico, ...
    Digestive and Liver Disease 58, S20-S21 , 2026
    2026
  • The Italian PBC Registry: Insights from a Nationwide Cohort Study
    E Nofit, L Cristoferi, A Gerussi, D D'amato, MMG Festa, E Bonaiuto, ...
    Digestive and Liver Disease 58, S99-S101 , 2026
    2026
  • The Burden of Extrahepatic Comorbidities in Primary Biliary Cholangitis: Insights from the Italian National PBC Registry
    N Cazzagon, A De Vincentis, M Benatti, E Nofit, F Terracciani, ...
    Digestive and Liver Disease 58, S14-S15 , 2026
    2026
  • HIV infection among adolescents and young adults in Italy: Epidemiology, viro-immunological and treatment outcomes
    FM Fusco, I Mastrorosa, F Vichi, A Cervo, A Saracino, L Calza, ...
    International Journal of Infectious Diseases, 108200 , 2025
    2025
  • Diagnosed Patients With Chronic Hepatitis B and Delta Virus in Italy in 2024: An Estimation From a National Real‐World Database
    A Loglio, I Gardini, M Conforti, M Bartoli, F Silvia, C Coppola, L Chessa, ...
    Liver International 45 (10), e70336 , 2025
    2025
    Citations: 2
  • Cancer incidence in people with HIV in Italy: Comparison of the ICONA COHORT with general population data
    P Piselli, A Tavelli, C Cimaglia, C Muccini, A Bandera, GC Marchetti, ...
    International Journal of Cancer 157 (6), 1142-1153 , 2025
    2025
    Citations: 4
  • Comparison of diagnostic performances of HDV RNA quantification assays used in clinical practice: results from a national quality control multicenter study
    R Salpini, L Piermatteo, GP Caviglia, A Bertoli, MR Brunetto, B Bruzzone, ...
    Journal of Clinical Virology, 105850 , 2025
    2025
    Citations: 7
  • Risk of clinical events in virologically suppressed people with HIV switching to a two-drug regimen vs. remaining on a three-drug regimen: a target trial emulation
    C Mussini, A Giacomelli, E Quiros-Roldan, V Mazzotta, A Di Biagio, ...
    EClinicalMedicine 86 , 2025
    2025
    Citations: 2
  • Long-term effectiveness, safety, and liver stiffness dynamics of PBC treatment with obeticholic acid in real-world
    F Terracciani, A De Vincentis, D D’Amato, L Cristoferi, A Gerussi, ...
    JHEP Reports 7 (8), 101448 , 2025
    2025
    Citations: 4
  • The role of HLA-G in primary biliary cholangitis and response to therapy
    M Miglianti, S Mocci, R Littera, G Serra, C Balestieri, M Conti, F Pes, ...
    Frontiers in Immunology 16, 1585535 , 2025
    2025
    Citations: 2
  • Safety and effectiveness of switch to bictegravir/emtricitabine/tenofovir alafenamide following dual regimen therapy in people with HIV: Insights from the Icona cohort
    A De Vito, A Tavelli, A Cozzi‐Lepri, A Giacomelli, R Rossotti, G Ponta, ...
    HIV medicine 26 (6), 970-977 , 2025
    2025
    Citations: 3
  • Effectiveness of dolutegravir-based vs boosted darunavir-based first-line 3-drug regimens in people with HIV with advanced disease: A trial emulation
    R Gagliardini, A Giacomelli, C Mussini, SR Cole, JK Edwards, C Pinnetti, ...
    International Journal of Infectious Diseases 155, 107883 , 2025
    2025
    Citations: 2
  • THU-272 Appraising improvement in prediction of clinical outcomes based on different response criteria and liver stiffness measurements in patients with primary biliary …
    A De Vincentis, F Terracciani, D D’Amato, L Cristoferi, A Gerussi, ...
    Journal of Hepatology 82, S307-S308 , 2025
    2025
    Citations: 1
  • Human leukocyte antigen-G in hepatocellular carcinoma driven by chronic viral hepatitis or steatotic liver disease
    S Mocci, A Perra, R Littera, F Pes, M Melis, C Sanna, A Mascia, M Murgia, ...
    Scientific Reports 15 (1), 13331 , 2025
    2025
    Citations: 3
  • Impact of the Human Leukocyte Antigen Complex on Idiopathic Pulmonary Fibrosis Development and Progression in the Sardinian Population
    M Serra, S Mocci, S Deidda, M Melis, L Chessa, S Lai, E Giuressi, ...
    International Journal of Molecular Sciences 26 (6), 2760 , 2025
    2025
  • Comparison of diagnostic performances of HDV RNA quantification assays used in clinical practice in Italy: data from the first national quality control multicenter study
    L Piermatteo, R Salpini, GP Caviglia, A Bertoli, MR Brunetto, B Bruzzone, ...
    Digestive and Liver Disease 57, S53-S54 , 2025
    2025
    Citations: 1
  • Virtual reality cognitive remediation tool for individuals with mild cognitive impairment: study protocol for a feasibility randomized clinical trial
    A Perra, D Primavera, V Leonetti, R Montisci, D Carta, G Lorrai, A Locci, ...
    Frontiers in Public Health 12, 1477279 , 2024
    2024
    Citations: 1
  • MICA and NKG2D gene polymorphisms influence graft survival, and response to therapy in kidney transplantation
    R Littera, S Mocci, D Argiolas, L Littarru, S Lai, M Melis, C Sanna, ...
    Frontiers in Immunology 15, 1440887 , 2024
    2024
    Citations: 5

MOST CITED SCHOLAR PUBLICATIONS

  • Long-term benefit of interferon α therapy of chronic hepatitis D: regression of advanced hepatic fibrosis
    P Farci, T Roskams, L Chessa, G Peddis, AP Mazzoleni, R Scioscia, ...
    Gastroenterology 126 (7), 1740-1749 , 2004
    2004
    Citations: 389
  • Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome
    P Farci, R Strazzera, HJ Alter, S Farci, D Degioannis, A Coiana, G Peddis, ...
    Proceedings of the National Academy of Sciences 99 (5), 3081-3086 , 2002
    2002
    Citations: 274
  • Randomised study comparing 48 and 96 weeks peginterferon α-2a therapy in genotype D HBeAg-negative chronic hepatitis B
    P Lampertico, M Viganò, GG Di Costanzo, E Sagnelli, M Fasano, ...
    Gut 62 (2), 290-298 , 2013
    2013
    Citations: 165
  • Human leukocyte antigen complex and other immunogenetic and clinical factors influence susceptibility or protection to SARS-CoV-2 infection and severity of the disease course …
    R Littera, M Campagna, S Deidda, G Angioni, S Cipri, M Melis, D Firinu, ...
    Frontiers in immunology 11, 605688 , 2020
    2020
    Citations: 145
  • Association of chronic hepatitis C with major depressive disorders: irrespective of interferon-alpha therapy
    MG Carta, MC Hardoy, A Garofalo, E Pisano, V Nonnoi, G Intilla, G Serra, ...
    Clinical Practice and Epidemiology in Mental Health 3 (1), 22 , 2007
    2007
    Citations: 138
  • Real-world experience with obeticholic acid in patients with primary biliary cholangitis
    D D’Amato, A De Vincentis, F Malinverno, M Viganò, D Alvaro, M Pompili, ...
    JHEP Reports 3 (2), 100248 , 2021
    2021
    Citations: 103
  • Further decompensation in cirrhosis: results of a large multicenter cohort study supporting Baveno VII statements
    G D’Amico, A Zipprich, C Villanueva, JA Sordà, RM Morillas, M Garcovich, ...
    Hepatology 79 (4), 869-881 , 2024
    2024
    Citations: 70
  • Association of chronic hepatitis C with recurrent brief depression
    MG Carta, J Angst, MF Moro, G Mura, MC Hardoy, C Balestrieri, L Chessa, ...
    Journal of affective disorders 141 (2-3), 361-366 , 2012
    2012
    Citations: 61
  • Treatment of chronic hepatitis D
    P Farci, L Chessa, C Balestrieri, G Serra, ME Lai
    Journal of viral hepatitis 14, 58-63 , 2007
    2007
    Citations: 61
  • Natural killer-cell immunoglobulin-like receptors trigger differences in immune response to SARS-CoV-2 infection
    R Littera, L Chessa, S Deidda, G Angioni, M Campagna, S Lai, M Melis, ...
    PLoS One 16 (8), e0255608 , 2021
    2021
    Citations: 56
  • Forecasting Hepatitis C liver disease burden on real‐life data. Does the hidden iceberg matter to reach the elimination goals?
    LA Kondili, S Robbins, S Blach, I Gamkrelidze, AL Zignego, MR Brunetto, ...
    Liver International 38 (12), 2190-2198 , 2018
    2018
    Citations: 53
  • Premature ovarian senescence and a high miscarriage rate impair fertility in women with HCV
    A Karampatou, X Han, LA Kondili, G Taliani, A Ciancio, F Morisco, ...
    Journal of Hepatology 68 (1), 33-41 , 2018
    2018
    Citations: 53
  • Modeling cost‐effectiveness and health gains of a “universal” versus “prioritized” hepatitis C virus treatment policy in a real‐life cohort
    LA Kondili, F Romano, FR Rolli, M Ruggeri, S Rosato, MR Brunetto, ...
    Hepatology 66 (6), 1814-1825 , 2017
    2017
    Citations: 52
  • Incidence of DAA failure and the clinical impact of retreatment in real-life patients treated in the advanced stage of liver disease: Interim evaluations from the PITER network
    LA Kondili, GB Gaeta, MR Brunetto, A Di Leo, A Iannone, TA Santantonio, ...
    PloS one 12 (10), e0185728 , 2017
    2017
    Citations: 52
  • Performance of the model for end-stage liver disease score for mortality prediction and the potential role of etiology
    G D’Amico, L Maruzzelli, A Airoldi, I Petridis, G Tosetti, A Rampoldi, ...
    Journal of hepatology 75 (6), 1355-1366 , 2021
    2021
    Citations: 40
  • Gastrointestinal coronavirus disease 2019: epidemiology, clinical features, pathogenesis, prevention, and management
    S Deidda, L Tora, D Firinu, S Del Giacco, M Campagna, F Meloni, G Orru, ...
    Expert Review of Gastroenterology & Hepatology 15 (1), 41-50 , 2021
    2021
    Citations: 38
  • Exploring the role of killer cell immunoglobulin-like receptors and their HLA class I ligands in autoimmune hepatitis
    R Littera, L Chessa, S Onali, F Figorilli, S Lai, L Secci, G La Nasa, ...
    PLoS One 11 (1), e0146086 , 2016
    2016
    Citations: 36
  • A prospective study of direct‐acting antiviral effectiveness and relapse risk in HCV cryoglobulinemic vasculitis by the Italian PITER cohort
    LA Kondili, M Monti, MG Quaranta, L Gragnani, V Panetta, G Brancaccio, ...
    Hepatology 76 (1), 220-232 , 2022
    2022
    Citations: 34
  • Add‐on peginterferon alfa‐2a to nucleos (t) ide analogue therapy for Caucasian patients with hepatitis B ‘e’antigen‐negative chronic hepatitis B genotype D
    P Lampertico, MR Brunetto, A Craxì, GB Gaeta, M Rizzetto, A Rozzi, ...
    Journal of Viral Hepatitis 26 (1), 118-125 , 2019
    2019
    Citations: 34
  • Predictors of serious adverse events and non‐response in cirrhotic patients with primary biliary cholangitis treated with obeticholic acid
    A De Vincentis, D D'Amato, L Cristoferi, A Gerussi, F Malinverno, A Lleo, ...
    Liver International 42 (11), 2453-2465 , 2022
    2022
    Citations: 32